Case Reports in Gastroenterology最新文献_第5页

Aseptic Abscess Syndrome: A Case Report of a Rare Extraintestinal Manifestation of Inflammatory Bowel Disease. 无菌性脓肿综合征：一例罕见的炎症性肠病肠外表现。

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-02-27 eCollection Date: 2025-01-01 DOI: 10.1159/000543761

Clive Jude Miranda, Nariman Hossein-Javaheri, Gina Marie Sparacino, Yousef Soofi, Farhan Azad, Nikki Duong

引用次数: 0

Effectiveness of Triamcinolone Injections in Preventing Scar Deformity following Endoscopic Submucosal Dissection for Pharyngeal Cancer. 曲安奈德注射预防咽癌内镜下粘膜下剥离术后瘢痕畸形的疗效。

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-02-25 eCollection Date: 2025-01-01 DOI: 10.1159/000543878

Yugo Suzuki, Shinji Ito, Tsuyoshi Ishii, Minoru Oda, Shu Hoteya

{"title":"Effectiveness of Triamcinolone Injections in Preventing Scar Deformity following Endoscopic Submucosal Dissection for Pharyngeal Cancer.","authors":"Yugo Suzuki, Shinji Ito, Tsuyoshi Ishii, Minoru Oda, Shu Hoteya","doi":"10.1159/000543878","DOIUrl":"https://doi.org/10.1159/000543878","url":null,"abstract":"Introduction: Endoscopic submucosal dissection (ESD) is an effective treatment for superficial pharyngeal cancer. However, pharyngeal deformity caused by postoperative ulcer contraction is a major concern and can result in a poor quality of life. While local steroid injections have been shown to prevent strictures after ESD for esophageal cancer, their effectiveness in preventing deformities following ESD for pharyngeal cancer remains unclear.Case presentation: A 60-year-old woman with superficial pharyngeal cancer in the left pyriform sinus underwent ESD. After ESD, 80 mg of triamcinolone acetonide was injected into the ulcer bed to prevent scar contracture. The patient experienced mild pharyngeal pain, which resolved within a few days. Histopathological examination confirmed the lesion was well-differentiated SCC, with negative resection margins and no lymphovascular invasion. Follow-up endoscopy at 6 weeks showed granulation tissue in the surgical wound, which completely healed without pharyngeal deformity by 14 weeks post-ESD.Conclusion: This case demonstrated that the injection of triamcinolone in an ulcer that developed after ESD may be an effective method of preventing pharyngeal deformity caused by scar contracture.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"19 1","pages":"113-119"},"PeriodicalIF":0.5,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11857159/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143977333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Intra-Abdominal Desmoid Tumor with Edematous Loose Collagen Fibers. 腹内硬纤维瘤伴疏松胶原纤维水肿。

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-02-25 eCollection Date: 2025-01-01 DOI: 10.1159/000543498

Mao Iino, Shoji Oura

{"title":"An Intra-Abdominal Desmoid Tumor with Edematous Loose Collagen Fibers.","authors":"Mao Iino, Shoji Oura","doi":"10.1159/000543498","DOIUrl":"10.1159/000543498","url":null,"abstract":"Introduction: Diagnostic physicians tend to judge a low-dense area on computed tomography (CT) as central necrosis when it has no contrast enhancement and locates in the center of large tumors.Case presentation: An 80-year-old woman was referred to our hospital due to the detection of an abdominal mass on ultrasound (US). CT showed a well-demarcated oval mass, 11 cm in size, with a central low-density area. US showed high internal echoes and enhanced posterior echoes. Magnetic resonance imaging (MRI) showed the low-density area on CT to be hypo-intense on T1-weighted images and hyper-intense on T2-weighted images. MRI further showed the central part of the tumor to be hyper-intense both on diffusion-weighted images and apparent diffusion coefficient images. Under the tentative diagnosis of a gastrointestinal stromal tumor with central necrosis, the patient underwent tumor resection, revealing the tumor to be a jejunal submucosal tumor. Pathological study showed collagen fibers with heterogeneous density and sparse proliferation of spindle cells. The center of the tumor had marked edema in addition to sparse collagen fibers. Immunostaining showed that the atypical cells were diffusely positive for β catenin and negative for S100 protein, desmin, and DOG1, leading to the diagnosis of desmoid tumor (DT).Conclusions: Physicians should note that intra-abdominal DT can have edematous loose collagen fibers and may show central necrosis-like findings on CT.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"19 1","pages":"107-112"},"PeriodicalIF":0.5,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11857155/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143499369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Drug-Induced Liver Injury Associated with Turmeric and Piperine: A Case and Review. 姜黄和胡椒碱相关的药物性肝损伤：一个病例和回顾。

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-02-24 eCollection Date: 2025-01-01 DOI: 10.1159/000543679

Atul Shrestha, Sarah Elliott, Joshua Haron Abasszade, Kyle Wu, Thomas Worland, Ian Simpson, Anouk Dev

{"title":"Drug-Induced Liver Injury Associated with Turmeric and Piperine: A Case and Review.","authors":"Atul Shrestha, Sarah Elliott, Joshua Haron Abasszade, Kyle Wu, Thomas Worland, Ian Simpson, Anouk Dev","doi":"10.1159/000543679","DOIUrl":"10.1159/000543679","url":null,"abstract":"Introduction: Turmeric is a common spice used in traditional Chinese and Ayurvedic medicine for a variety of purported health benefits. Recent concerns have arisen regarding turmeric-induced liver injury linked to formulations with enhanced bioavailability, often including piperine found in black pepper.Case presentation: We explore a case of a 40-year-old female with increasing fatigue, pruritus, and dark urine following consumption of turmeric and black pepper \"wellness shots\" leading to a significant drug-induced liver injury.Conclusion: This case underscores the critical need to recognise herbal remedies, such as turmeric, as potential sources of hepatotoxicity. Despite a reputation of safety, limited regulation and testing of turmeric may mean potential adverse effects are under-recognised. Understanding the mechanisms behind turmeric and black pepper's hepatotoxicity, including the role of potential genetic predispositions, requires further investigation for its safe use.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"19 1","pages":"96-106"},"PeriodicalIF":0.5,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11850025/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143490900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inflammatory Bowel Disease in a Patient Returning from Colombia: Association with Dipeptidyl Peptidase 4 Inhibitor? 从哥伦比亚回来的炎症性肠病患者：与二肽基肽酶4抑制剂有关？

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-02-21 eCollection Date: 2025-01-01 DOI: 10.1159/000543680

Ahmed B Bayoumy, Gwen M C Masclee, Nanne K H de Boer, Andra Neefjes-Borst, Dirk Jan Stenvers

{"title":"Inflammatory Bowel Disease in a Patient Returning from Colombia: Association with Dipeptidyl Peptidase 4 Inhibitor?","authors":"Ahmed B Bayoumy, Gwen M C Masclee, Nanne K H de Boer, Andra Neefjes-Borst, Dirk Jan Stenvers","doi":"10.1159/000543680","DOIUrl":"10.1159/000543680","url":null,"abstract":"Introduction: Recent-onset colitis poses a diagnostic challenge, necessitating a thorough evaluation to identify potential infectious and non-infectious etiologies. We considered inflammatory bowel disease (IBD) secondary to dipeptidyl peptidase 4 (DPP-4) inhibitor-induced colitis.Case presentation: This case report details the presentation and management of a patient with persistent dysentery, refractory to conventional treatments, ultimately attributed to IBD possibly secondary to long-term DPP-4 inhibitor use. Following an episode of suspected amebiasis, the patient experienced prolonged bloody diarrhea with an endoscopic image compatible with ulcerative colitis. Extensive infectious diagnostics were negative. Ultimately, the cessation of sitagliptin therapy resulted in rapid symptom resolution and normalization of eosinophilia, as well as endoscopic improvement. However, after a few weeks, the patient was readmitted with diarrhea after continued cessation of sitagliptin.Conclusion: This case underscores the importance of considering IBD secondary to DPP-4 inhibitor use in the evaluation of patients with recent-onset IBD. Further research is needed to elucidate the pathophysiological mechanisms underlying the relationship between DPP-4 inhibitors and IBD.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"19 1","pages":"89-95"},"PeriodicalIF":0.5,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11845166/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Severe Acute Pancreatitis Complicated by Multiple Intra-Abdominal Hemorrhages. 重症急性胰腺炎并发多发性腹腔出血。

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-02-19 eCollection Date: 2025-01-01 DOI: 10.1159/000543626

Cong-Yu Wang, Yin Gu, Rui-Peng Yan, Xin Li, Fei He, Xiang-Lan Feng, Gen Zhang, Yun-Feng Cui

{"title":"Severe Acute Pancreatitis Complicated by Multiple Intra-Abdominal Hemorrhages.","authors":"Cong-Yu Wang, Yin Gu, Rui-Peng Yan, Xin Li, Fei He, Xiang-Lan Feng, Gen Zhang, Yun-Feng Cui","doi":"10.1159/000543626","DOIUrl":"10.1159/000543626","url":null,"abstract":"Introduction: Intra-abdominal hemorrhage is a rare yet life-threatening complication of acute pancreatitis (AP), with a higher prevalence in cases of severe acute pancreatitis (SAP). This condition is primarily caused by vessel wall erosion and rupture of pseudoaneurysms (PSAs). However, SAP cases involving multiple sequential arterial hemorrhages are extremely rare. This condition is primarily brought on by the process of vessel wall degeneration and the development of PSAs. Nonetheless, SAP necessitating multiple episodes of arterial bleeding is very uncommon.Case presentation: Here is the case history of a 31-year-old man already being treated for SAP. His condition was then complicated by massive, frequent intra-abdominal bleeding. The patient initially presented to the hospital with SAP. He was transferred to the intensive care unit for proper management. Massive intra-abdominal bleeds occurred on the 31st, 45th, and 60th days during hospitalization. The maximum blood loss was 1,500 mL. In each of the instances, digital subtraction angiography (DSA) embolization was carried out after the bleeding source had been verified. In order to manage SAP, continuous percutaneous drainage and staged pancreatic necrosectomy were undertaken for 6 months. No recurrence of intra-abdominal hemorrhage was detected. Infection of the abdominal cavity was properly controlled. The patient left the hospital in good condition.Conclusion: Spontaneous bleeding in the abdominal cavity is a severe and life-threatening complication of SAP. This is often caused by vessel wall erosion. In such cases, DSA plays a crucial role in diagnosis and management. Besides precisely locating the bleeding source, one can perform a much-needed embolization immediately. Consequently, the disease is under total control, and the patient is much more likely to survive.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"19 1","pages":"79-88"},"PeriodicalIF":0.5,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11839214/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143457018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hybrid Endoscopic/Fluoroscopic Gastrostomy Tube Placement: Case Report of a Novel Technique. 内镜/透视混合胃造口管置入：一种新技术的病例报告。

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-02-18 eCollection Date: 2025-01-01 DOI: 10.1159/000542809

Nicholas Girardi, Benjamin Wharton, Kenneth Cicuto, Alysia Wiley, Lacey LaGrone

引用次数: 0

Management of Refractory Esophageal Variceal Bleeding when TIPSS Is Not Possible: Review of a Challenging Case. 当TIPSS不可能时难治性食管静脉曲张出血的处理：回顾一个具有挑战性的病例。

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-02-13 eCollection Date: 2025-01-01 DOI: 10.1159/000543537

Abdulrahman Qatomah, Ali Bessissow, Yen-I Chen, Talat Bessissow, Amine Benmassaoud

引用次数: 0

Anaphylaxis to a Vedolizumab Infusion following Drug Holiday in a Patient with Ulcerative Colitis: A Case Report. 溃疡性结肠炎患者在药物假期后对Vedolizumab输注的过敏反应：1例报告。

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-02-12 eCollection Date: 2025-01-01 DOI: 10.1159/000543387

Jadon Karp, Henry Shen, Thomas Goodwin, Miles P Sparrow

{"title":"Anaphylaxis to a Vedolizumab Infusion following Drug Holiday in a Patient with Ulcerative Colitis: A Case Report.","authors":"Jadon Karp, Henry Shen, Thomas Goodwin, Miles P Sparrow","doi":"10.1159/000543387","DOIUrl":"10.1159/000543387","url":null,"abstract":"Introduction: Vedolizumab is a commonly prescribed biologic agent due to its safety profile and clinical efficacy. Severe infusion-related reactions are exceedingly rare, with no previously documented cases of anaphylaxis to vedolizumab infusion following a drug holiday.Case presentation: We report the case of a 65-year-old male with ulcerative colitis who had a severe anaphylactic reaction to the first re-induction infusion of vedolizumab following a 30-month drug holiday. No pre-infusion prophylactic medication was administered. Upon commencement of the infusion, the patient developed anaphylactic symptoms including airway compromise that required intensive care unit admission and treatment with an adrenaline infusion.Conclusion: Anaphylactic reactions to vedolizumab after a drug holiday can occur. As is done for infliximab, we recommend administration of an antipyretic, antihistamine, and corticosteroid prior to vedolizumab re-induction infusions when it is given after a drug holiday.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"19 1","pages":"62-66"},"PeriodicalIF":0.5,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11820661/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful Pregnancy in a Patient with Crohn's Disease and Short Bowel Syndrome: Off Total Parenteral Nutrition and On Teduglutide, a Glucagon-Like Peptide-2 Analog - A Case Report. 克罗恩病和短肠综合征患者成功怀孕：脱离全肠外营养并服用胰高血糖素样肽-2类似物泰度鲁肽--病例报告。

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-02-04 eCollection Date: 2025-01-01 DOI: 10.1159/000543291

Maria M Dahar, MacKenzie Both, Linda M Lord, Carly Densmore, Lawrence J Saubermann

{"title":"Successful Pregnancy in a Patient with Crohn's Disease and Short Bowel Syndrome: Off Total Parenteral Nutrition and On Teduglutide, a Glucagon-Like Peptide-2 Analog - A Case Report.","authors":"Maria M Dahar, MacKenzie Both, Linda M Lord, Carly Densmore, Lawrence J Saubermann","doi":"10.1159/000543291","DOIUrl":"10.1159/000543291","url":null,"abstract":"Introduction: Patients with short bowel syndrome (SBS) on conventional oral diets often face nutritional deficiencies and dehydration, a challenge further compounded during pregnancy. This case report describes the use of a glucagon-like peptide-2 (GLP-2) analog in the nutritional management of an SBS patient dependent on total parenteral nutrition (TPN).Case presentation: A 29-year-old woman with a significant medical history of Crohn's disease leading to SBS was traditionally dependent on TPN for sustenance. During her pregnancy, she was successfully managed with a GLP-2 analog, which enabled her to wean off TPN. This successful management underscores the therapeutic potential of GLP-2 analogs in effectively altering the nutritional landscape for SBS patients, including during the physiologically demanding period of pregnancy.Conclusion: GLP-2 analogs helped with the nutritional management of patients with SBS during pregnancy and helped them wean off TPN. There is a need for further research and exploration into GLP-2 analogs as viable alternatives to conventional treatments such as TPN in the care and management of SBS patients during pregnancy.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"19 1","pages":"57-61"},"PeriodicalIF":0.5,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11793910/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143188412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0