RSC AdvancesPub Date : 2025-09-05DOI: 10.1039/D5RA03280F
Koffi Koffi Kra Sylvestre, Dan Li, Essy Kouadio Fodjo, Aka Alla Martin, Pomi Bi Boussou Narcisse and Irié Bi Irié Williams
{"title":"Fast detection of melamine using silver nanoparticles capped with l-cysteine functionalized carbon dots","authors":"Koffi Koffi Kra Sylvestre, Dan Li, Essy Kouadio Fodjo, Aka Alla Martin, Pomi Bi Boussou Narcisse and Irié Bi Irié Williams","doi":"10.1039/D5RA03280F","DOIUrl":"https://doi.org/10.1039/D5RA03280F","url":null,"abstract":"<p >Melamine is an additive used fraudulently to enrich foods with nitrogen, particularly in the dairy industry. It is also known as the main metabolite or degradation phytosanitary product of cyromazine. However, the numerous incidents involving living beings in aquatic environments, children and pets fed with products made from melamine in China and certain African countries have led to distrust of melamine in food. In order to ensure strong food safety and security, and good quality of the ecosystem free of melamine, it is important to design a fast, simple, reliable and efficient method for the detection of melamine. For this purpose, silver nanoparticles capped with <small>L</small>-cysteine functionalized carbon dots (cCDs/AgNPs) were designed for the detection of melamine. The results showed that a yellow solution of cCDs/AgNPs turns pink and gradually blue within two minutes of heating at 90 °C in the presence of melamine even at a concentration of 0.1 μg mL<small><sup>−1</sup></small>. This color change reflects the sensitivity of cCDs/AgNPs towards melamine. The investigation of cCDs/AgNPs-based on ultraviolet-visible spectroscopy exhibits good linearity in the range from 0.5 μg mL<small><sup>−1</sup></small> to 4.5 μg mL<small><sup>−1</sup></small> for melamine detection, with a detection limit of 0.03 μg mL<small><sup>−1</sup></small>. This method was successfully applied to determine melamine in a milk matrix, suggesting that this method can be applied for food monitoring with the aim of obtaining melamine-free food in dairy products.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 39","pages":" 32031-32040"},"PeriodicalIF":4.6,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ra/d5ra03280f?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144990369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RSC AdvancesPub Date : 2025-09-05DOI: 10.1039/D5RA04233J
Nadia Anter, Ahlam Chennani, Mohamed-Yassine Guida, Fatima ezzahra Atmani, Amine Moubarik, El Mostapha Rakib, Abdelouahid Medaghri-Alaoui and Abdellah Hannioui
{"title":"Dual-functionalized lignin as a sustainable modifier for high-performance phenol-formaldehyde adhesives in plywood production","authors":"Nadia Anter, Ahlam Chennani, Mohamed-Yassine Guida, Fatima ezzahra Atmani, Amine Moubarik, El Mostapha Rakib, Abdelouahid Medaghri-Alaoui and Abdellah Hannioui","doi":"10.1039/D5RA04233J","DOIUrl":"https://doi.org/10.1039/D5RA04233J","url":null,"abstract":"<p >Biopolymers derived from natural sources are sustainable, non-toxic, and biodegradable, making them attractive alternatives to fossil-based polymers. Among these, lignin has garnered significant attention due to its potential in adhesive applications. In this study, lignin was extracted from redwood (<em>Pinus sylvestris</em> L.) sawdust using an alkaline delignification process and subsequently modified through propargylation and silanization. Comprehensive characterization using FTIR, solubility tests, TGA/DTG, <small><sup>1</sup></small>H NMR, SEM-EDX, and contact angle measurements confirmed significant improvements in physicochemical properties. Notably, silylated lignins exhibited enhanced solubility in low-polarity solvents and a marked increase in hydrophobicity, with water contact angles reaching 127.7°. Phenol-formaldehyde (PF) adhesives incorporating raw and modified lignins (5–15 wt%) were formulated and applied in plywood production. Mechanical testing revealed that plywood bonded with 10 wt% Prop-lignin-DH achieved a bond strength of 5.44 MPa and 100% wood failure, outperforming conventional lignin-based adhesives. Furthermore, compared to the control PF resin, the modulus of rupture (MOR) and modulus of elasticity (MOE) increased by 38% and 27.3%, respectively. Shear strength also improved significantly, with gains of 56.1% under dry conditions, 17.6% in cold water, and 74.1% after boiling. In addition, formaldehyde emissions were reduced by 20% compared to standard PF resins, highlighting the potential of silylated lignin as a sustainable adhesive modifier for wood-based composites.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 39","pages":" 32118-32130"},"PeriodicalIF":4.6,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ra/d5ra04233j?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144998385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Liquid-phase microextraction method for the separation of hexavalent and total chromium in environmental water samples with spectrophotometric detection.","authors":"Zekeriyya Bahadır, Demet Tasmacıoğlu","doi":"10.1039/d5ay01075f","DOIUrl":"https://doi.org/10.1039/d5ay01075f","url":null,"abstract":"<p><p>Metal pollution, particularly chromium, in water and food samples is a critical issue due to its transfer to the human body through the food chain and its threat to human health. Among the chromium species that can be found in water samples, chromates are classified as toxic by scientific authorities. Spectroscopic instruments have limitations in metal speciation analysis, and there is a need for suitable methods that allow chromium speciation. In this work, a simple microextraction method was presented to extract Cr(VI) into an extraction solvent after it was complexed with a cationic reagent named benzyldimethyltetradecylammonium chloride, followed by measurement using ultraviolet-visible spectrometry. Total chromium was obtained after the oxidation of Cr(III) to Cr(VI) using a sulfuric acid/potassium permanganate/potassium oxalate combination. The method allows for a calibration curve (0.015-0.35 mg L<sup>-1</sup>) and a low detection limit (1.8 μg L<sup>-1</sup>) for the quantification of Cr(VI) and total Cr in seawater and wastewater samples. The accuracy of the proposed method was evaluated by the spiking-recovery method, with recoveries in the range of 91-103% for real water samples, and a certified reference material (LGC6026) was analyzed using the method for the determination of chromium content. In this work, benzyldimethyltetradecylammonium chloride (also known as the zephiramine ion, a disinfectant and antimicrobial agent commonly used in medical treatments) is used for the first time in a microextraction method for complexing with Cr(VI). The combination of microextraction with ultraviolet-visible spectrometry also makes this method low-cost and easy to apply in general chemistry laboratories. In addition, the presented method provides a more convenient oxidation procedure from Cr(III) to Cr(VI) in acidic media, using potassium oxalate instead of sodium azide to remove excess potassium permanganate.</p>","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144999224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Robust dehydrofluorination of HFC-245fa to HFO-1234ze <i>via in situ</i> VOFx formation over a non-oxalic acid assisted V<sub>2</sub>O<sub>5</sub>/γ-Al<sub>2</sub>O<sub>3</sub> catalyst.","authors":"Fizzah Fatima, Mudadla Umamaheswara Rao, Guo-Ping Chang-Chien, Srinivaas Masimukku, Giridhar Madras, Gedu Satyanarayana, Subrahmanyam Challapalli","doi":"10.1039/d5nh00366k","DOIUrl":"https://doi.org/10.1039/d5nh00366k","url":null,"abstract":"<p><p>The demand for trans-1,3,3,3-tetrafluoropropene [HFO-1234ze(E)] as a next-generation, low-global-warming-potential (GWP) refrigerant is rising due to international restrictions on high-GWP refrigerants like chlorofluorocarbons (CFCs), hydrochlorofluorocarbons (HCFCs) and hydrofluorocarbons (HFCs). Catalytic dehydrofluorination of HFC-245fa offers a viable synthesis route for the production of HFO-1234ze(E), but the catalyst degradation under harsh acidic conditions remains a major challenge. In this study, a highly stable γ-Al<sub>2</sub>O<sub>3</sub> supported catalyst was developed for efficient dehydrofluorination with vanadium species exhibiting the highest activity among the screened metal ions Ni<sup>2+</sup>, V<sup>5+</sup>, Zn<sup>2+</sup>, La<sup>3+</sup>, Fe<sup>3+</sup>, Mn<sup>2+</sup> and Cu<sup>2+</sup>. The optimized 15 wt% V<sub>2</sub>O<sub>5</sub>/γ-Al<sub>2</sub>O<sub>3</sub> catalyst, prepared without oxalic acid assistance, exhibited strong metal-support interactions and demonstrated superior catalytic performance achieving ∼95% HFC-245fa conversion. The catalyst activity increased from 1.3 to 2.1 μmol s<sup>-1</sup> g<sub>cat</sub><sup>-1</sup> due to the formation of <i>in situ</i> VOFx species generated through the interaction between V<sub>2</sub>O<sub>5</sub> and HF, as confirmed from NH<sub>3</sub>-TPD and XPS analysis. The catalyst also exhibited ∼81% selectivity towards HFO-1234ze(E) at 350 °C. It is noteworthy that the catalyst maintained a stable performance up to 74 h, without significant deactivation. Overall, these results highlight the importance of rational metal selection, loading optimization, and interface engineering in developing robust catalysts for industrial hydrofluoroolefin production.</p>","PeriodicalId":93,"journal":{"name":"Nanoscale Horizons","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144999271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Iron-catalyzed continuous-flow synthesis of sulfoxide with hydrogen peroxide.","authors":"Yasushi Okamoto, Kazuhiro Matsumoto, Jun-Chul Choi, Yoshihiro Kon, Ken-Ichi Fujita","doi":"10.1039/d5ob01254f","DOIUrl":"https://doi.org/10.1039/d5ob01254f","url":null,"abstract":"<p><p>A continuous-flow synthesis of sulfoxides from sulfides was achieved <i>via</i> oxidation with hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) in the presence of the catalyst generated <i>in situ</i> by simply packing a reactor column with a mixture of iron(III) chloride (FeCl<sub>3</sub>) and activated carbon followed by the pre-activation step in which an H<sub>2</sub>O<sub>2</sub>-acetonitrile solution was passed into the column. This activation step appeared to convert FeCl<sub>3</sub> to iron oxide species, thereby enhancing catalytic efficiency. Sulfoxides were continuously produced in >90% yield for up to 150 h. Although over-oxidation to sulfones occurred, the selectivity for some sulfoxides (defined as sulfoxide/(sulfoxide + sulfone)) reached up to 98%, with no residual sulfides, by fine-tuning the flow rate of the reaction solution.</p>","PeriodicalId":96,"journal":{"name":"Organic & Biomolecular Chemistry","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144999288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RSC AdvancesPub Date : 2025-09-05DOI: 10.1039/D5RA05056A
Yang Lyu, ZiQian Xiang, LuoJia Chen, Zuo Sheng Li, Jiangfeng Wang, Kuo Chen, Daofa Ying, BaoHui Chen and ChuanPing Wu
{"title":"Solvent-free fabrication of TPU-reinforced PE/carbon composites for high-performance positive temperature coefficient materials in lithium-ion battery safety","authors":"Yang Lyu, ZiQian Xiang, LuoJia Chen, Zuo Sheng Li, Jiangfeng Wang, Kuo Chen, Daofa Ying, BaoHui Chen and ChuanPing Wu","doi":"10.1039/D5RA05056A","DOIUrl":"https://doi.org/10.1039/D5RA05056A","url":null,"abstract":"<p >Positive temperature coefficient (PTC) materials are pivotal for safeguarding lithium iron phosphate batteries, yet their industrial application is hindered by critical drawbacks: excessive film thickness, high internal resistance, and poor solvent sustainability. Addressing these challenges, this study innovatively develops a solvent-free thermal rolling process to fabricate an asymmetric expansion polymer film, specifically thermoplastic polyurethane (TPU) reinforced polyethylene (PE)/carbon composites, which significantly enhances the PTC effect. The core mechanism lies in the asymmetric thermal expansion of TPU and PE: this unique behavior disrupts the conductive carbon network, triggering a sharp PTC transition at around 120 °C. Further validation <em>via</em> an electrochemical-thermal coupling model confirms that the abrupt resistance increase effectively terminates battery discharge, a key safety function. The optimized composite (1% TPU-1% C@PE) exhibits exceptional performance: it features an ultrathin structure (8.5 μm) with low resistance (78 Ω) at room temperature, while reaching a high-resistance state (10 380 Ω) at 120 °C, achieving an impressive resistance ratio of 133.1. Notably, this performance is achieved without compromising the battery's cycling stability. The open circuit voltage of the 1% TPU-1% C@PE battery can quickly drop to 2.5 V within 570 s in an environment of 160 °C, due to the PTC effect. This work not only overcomes long-standing industrial bottlenecks but also provides a practical, scalable strategy, paving the way for advanced safety in lithium battery technology.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 39","pages":" 32071-32079"},"PeriodicalIF":4.6,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ra/d5ra05056a?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144990377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Meijun Wang, Yujing Sang, Xinyu Qin, Li Ji, Hao Wang, Rui Yu, Tiantian Jin, Yiqing Lu, Yue Cong, Bingyang Shi
{"title":"Glycyrrhetinic acid functionalized polyamidoamine dendrimers for targeted gene delivery in liver cancer.","authors":"Meijun Wang, Yujing Sang, Xinyu Qin, Li Ji, Hao Wang, Rui Yu, Tiantian Jin, Yiqing Lu, Yue Cong, Bingyang Shi","doi":"10.1039/d5bm01037c","DOIUrl":"https://doi.org/10.1039/d5bm01037c","url":null,"abstract":"<p><p>Gene therapy holds significant promise for the treatment of liver cancer. However, the development of safe and efficient gene delivery systems remains a critical challenge. Cationic polymers are widely utilized as gene carriers due to their high transfection efficiency, yet their application is often hindered by cytotoxicity and lack of target specificity. In this study, we present a one-step strategy to conjugate glycyrrhetinic acid (GA) to cationic polymers, aiming to reduce cytotoxicity and enhance liver-specific targeting. A series of GA-modified polyamidoamine (PPI) dendrimers were synthesized by varying the degree of GA substitution and were comprehensively characterized. The resulting GA-PPI dendrimers exhibited strong plasmid DNA (pDNA) binding and protection capabilities, forming stable GA-PPI/pDNA polyplexes. Notably, GA-PPI dendrimers with 5.10% GA substitution achieved a 5.1-fold enhancement in hepatocyte transfection efficiency (22.7% <i>vs.</i> 4.45% for unmodified PPI), while maintaining high cell viability (97.8% <i>vs.</i> 76.4%). <i>In vivo</i>, GA-PPI-3/pDNA polyplexes demonstrated superior antitumor efficacy in HepG2 xenograft models. These results underscore the potential of GA-functionalized PPI dendrimers as an effective and safe platform for targeted gene therapy in hepatocellular carcinoma.</p>","PeriodicalId":65,"journal":{"name":"Biomaterials Science","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144999285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RSC AdvancesPub Date : 2025-09-05DOI: 10.1039/D5RA03970C
A. Ashok, Karthick Sekar, D. Acosta, Hind Saeed Alzahrani, Amani H. Alfaifi and Talaat A. Hameed
{"title":"Maneuvering investigation of theoretical and experimental parameters for Al-doped Cu (In, Ga) Se2 thin film solar cells with and without a back surface field layer","authors":"A. Ashok, Karthick Sekar, D. Acosta, Hind Saeed Alzahrani, Amani H. Alfaifi and Talaat A. Hameed","doi":"10.1039/D5RA03970C","DOIUrl":"https://doi.org/10.1039/D5RA03970C","url":null,"abstract":"<p >Aluminum-doped copper indium gallium selenide/sulfide (CIGAS) is a favorable absorber material for solar cell applications; however, the number of reports on CIGAS solar cells currently remains limited. In this study, we therefore employed SCAPS-1D software for the theoretical modeling of CIGAS thin film solar cells and investigated the effect of material properties and device configurations on solar cell photovoltaic (PV) parameters. Initially, key parameters such as thickness and charge carrier concentrations of each layer used in CIGAS PV devices were studied and optimized to obtain suitable conditions for high device performance. The impact of the various buffer window layers (BWL)—such as CdS, In<small><sub>2</sub></small>S<small><sub>3</sub></small>, ZnS, ZnSe, In<small><sub>2</sub></small>Se<small><sub>3</sub></small>, V<small><sub>2</sub></small>O<small><sub>5</sub></small>, ZnO, and MgZnO—as well as the back surface field (BSF) layers, including Sb<small><sub>2</sub></small>Se<small><sub>3</sub></small>, AlSb, CuGaSe<small><sub>2</sub></small>, SnS, BaSi<small><sub>2</sub></small>, MoS<small><sub>2</sub></small>, MoSe<small><sub>2</sub></small>, p-Si, CuS, and WSe<small><sub>2</sub></small>, was systematically tested to determine a CIGAS solar cell configuration with greater efficiency. After meticulous optimization, CdS and Sb<small><sub>2</sub></small>Se<small><sub>3</sub></small> materials were selected as the best BWL and BSF layers for the CIGAS device configuration, respectively, demonstrating a maximum power conversion efficiency (PCE) of 32.2% compared to other chosen materials. Finally, an experimentally obtained CIGAS absorber and CdS buffer material properties were introduced into optimized conditions with and without a BSF layer to further analyze their influence on solar cell performance. This also confirmed that the BSF layer significantly boosts device efficiency compared to the conventional CIGAS device.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 38","pages":" 31899-31916"},"PeriodicalIF":4.6,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ra/d5ra03970c?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144990366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yilei Li, Peng Song, Juan Wang, Yili Tong, Xiaojing Hao, Hongwei Shi, Pei Ma, Shusen Ji, Xiuju Yu, Yi Yan, Jiayin Lu, Xiaomao Luo, Yanjun Dong, Haidong Wang
{"title":"Yolk extract-derived vitellogenin 2 ameliorates muscle atrophy in mice <i>via</i> the PI3K/AKT/mTOR pathway.","authors":"Yilei Li, Peng Song, Juan Wang, Yili Tong, Xiaojing Hao, Hongwei Shi, Pei Ma, Shusen Ji, Xiuju Yu, Yi Yan, Jiayin Lu, Xiaomao Luo, Yanjun Dong, Haidong Wang","doi":"10.1039/d4fo06188h","DOIUrl":"https://doi.org/10.1039/d4fo06188h","url":null,"abstract":"<p><p>Eggs play an important role in skeletal muscle development, but their active components are unknown. The aim of this study was to investigate the effect of yolk extract-derived vitellogenin 2 on dexamethasone (DEX)- and cancer cachexia (CC)-induced skeletal muscle atrophy. We used iTRAQ to detect the changes in protein expression between fertilized egg yolk extract (FEYE) and unfertilized egg yolk extract (UEYE). Results showed that 15 proteins were up-regulated and 1 protein was down-regulated, and the expression of VTG2 (vitellogenin 2) was the highest in both FEYE and UEYE. Further research demonstrated that VTG2 can promote the proliferation and differentiation of myoblasts <i>in vitro</i>. We later proved that VTG2 not only improved the muscle atrophy in 7-week-old male C57BL/6 mice but also inhibited the decrease in P-AKT levels induced by the muscle atrophy model. At the same time, it was proved that VTG2 can improve autophagy, inflammation and mitochondrial dysfunction caused in a myotube atrophy model. Subsequent research proved that PI3K/AKT/mTOR was considered an important pathway for VTG2 to improve muscle atrophy. Therefore, the above results proved that FEYE can improve muscle atrophy through the PI3K/AKT/mTOR pathway mediated by VTG2. This study clarified the role of VTG2 in skeletal muscle atrophy and proved that VTG2 has potential application value in the prevention of diseases related to skeletal muscle atrophy.</p>","PeriodicalId":77,"journal":{"name":"Food & Function","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144999238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aleksandr S Aglikov, Mikhail V Zhukov, Timur A Aliev, Vladislav I Maslii, Paul V Gelfenshtein, Dmitry A Kozodaev, Daria V Andreeva, Michael Nosonovsky, Ekaterina V Skorb
{"title":"Numerical and topological description of contact areas at different size scales for the contact of rough solid surfaces.","authors":"Aleksandr S Aglikov, Mikhail V Zhukov, Timur A Aliev, Vladislav I Maslii, Paul V Gelfenshtein, Dmitry A Kozodaev, Daria V Andreeva, Michael Nosonovsky, Ekaterina V Skorb","doi":"10.1039/d5mh01327e","DOIUrl":"https://doi.org/10.1039/d5mh01327e","url":null,"abstract":"<p><p>This study introduces a novel heuristic phenomenological model for analyzing the evolution of contact areas on rough surface. Contrasting with traditional methods, it employs a cut-off threshold approach to track numerical and topological metrics across different deformation stages. The model quantifies contact area distributions, nested sub-regions, and self-affine parameters, revealing universal trends across scales spanning nanometers to kilometers. Metrics for synthetically generated isotropic surfaces with Hurst exponents <i>H</i> = 2.5 and 3.5 correlate closely with those from AFM and SEM experimental datasets, respectively. In addition, the model has been tested on NASA's SRTM datasets. Cross-correlation demonstrate significant similarities in numerical and topological metrics across diverse measurement techniques, surface types, and scales, highlighting the method's robustness and calibration-free scale invariance. This approach bridges gaps in multiscale tribological analysis, offering deeper insights into frictional transitions and surface interactions. Beyond tribology and materials science, this general approach enables fundamental characterization of surface morphology as such, making it applicable to diverse fields including geomorphology, biomimetics, and nanotechnology.</p>","PeriodicalId":87,"journal":{"name":"Materials Horizons","volume":" ","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144999204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}