The Royal Society of Chemistry最新文献

{"title":"One-step construction of carbon nanoparticle/graphene oxide nanofiltration membranes with uniform sandwich structure for enhanced water purification†","authors":"Xue Zhang, Ziyi Sang, Leiyang Xue and Lianwen Zhu","doi":"10.1039/D5RA00454C","DOIUrl":"https://doi.org/10.1039/D5RA00454C","url":null,"abstract":"<p >Graphene-based membranes have great potential for water purification. However, it is still a challenge to achieve high solute rejection at high water flow by controlling the water permeation channel. Herein, carbon nanoparticles (CNPs) were uniformly sandwiched between graphene oxide (GO) sheets by one-step vacuum-assisted filtration of CNPs and GO mixed solution, resulting in the formation of CNPs/GO composite nanofiltration membranes with uniform sandwich structure. The addition of CNPs in the composite membrane could help to form a continuous transverse channel of water permeation and greatly increase the water flow. The results showed that the CNPs/GO composite membrane with a mass ratio of 20% exhibited the best performance. The pure water flow rate was 49.9 L m<small>⁻²</small> h<small>⁻¹</small>, which was 21 times higher than that of the pure GO membrane. The rejection rate for four different organic dyes exceeded 97%. The rejection rate for methylene blue (MB) was still 94.7% after 8 recycling cycles. In addition, the membranes allow the penetration of salts, which makes them promising for dye wastewater desalination. This study provides a simple and effective strategy to tune the channel microstructure of the composite membranes and increases the understanding of the important role of the sandwich particles in achieving a better performance of the membranes.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 13","pages":" 9618-9626"},"PeriodicalIF":3.9,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ra/d5ra00454c?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143726604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A stepwise dearomatization/nitration/enantioselective homoenolate reaction of quinolines to construct C₃-nitro-substituted tetrahydroquinolines.","authors":"Aniruddh Pratap, Biswajit Maji","doi":"10.1039/d5ob00247h","DOIUrl":"https://doi.org/10.1039/d5ob00247h","url":null,"abstract":"<p><p>Herein, we describe a stepwise 1,2-reductive dearomatization/selective C₃-nitration of quinoline and a subsequent catalytic enantioselective homoenolate addition reaction using a NHC catalyst strategy to construct <i>N</i>-acetyl 3,4-disubstituted tetrahydroquinoline in good yields with remarkably high diastereo- and enantioselectivities (dr >99 : 1, ee up to >99%). An efficient metal- and base-free method for 3-nitroquinoline synthesis from readily accessible quinoline has also been realized.</p>","PeriodicalId":96,"journal":{"name":"Organic & Biomolecular Chemistry","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional assessment of migration and adhesion to quantify cancer cell aggression.","authors":"Lauren E Mehanna, James D Boyd, Chloe G Walker, Adrianna R Osborne, Martha E Grady, Brad J Berron","doi":"10.1039/d4sm01351d","DOIUrl":"https://doi.org/10.1039/d4sm01351d","url":null,"abstract":"<p><p>During epithelial-to-mesenchymal transition (EMT), cancer cells lose their cell-cell adhesion junctions as they become more metastatic, altering cell motility and focal adhesion disassembly associated with increased detachment from the primary tumor and a migratory response into nearby tissue and vasculature. Current <i>in vitro</i> strategies characterizing a cell's metastatic potential heavily favor quantifying the presence of cell adhesion biomarkers through biochemical analysis; however, mechanical cues such as adhesion and motility directly relate to cell metastatic potential without needing to first identify a cell specific biomarker for a particular type of cancer. This paper presents a comprehensive comparison of two functional metrics of cancer aggression, wound closure migration velocity and cell detachment from a culture surface, for three pairs of epithelial cancer cell lines (breast, endometrium, tongue tissue origins). It was found that one functional metric alone was not sufficient to categorize the cancer cell lines; instead, both metrics were necessary to identify functional trends and accurately place cells on the spectrum of metastasis. On average, cell lines with low metastatic potential (MCF-7, Ishikawa, and Cal-27) were more aggressive through wound closure migration compared to loss of cell adhesion. On the other hand, cell lines with high metastatic potential (MDA-MB-231, KLE, and SCC-25) were on average more aggressive through loss of cell adhesion compared to wound closure migration. This trend was true independent of the tissue type where the cells originated, indicating that there is a relationship between metastatic potential and the predominate type of cancer aggression. Our work presents one of the first combined studies relating cell metastatic potential to functional migration and adhesion metrics across cancer cell lines from selected tissue origins, without needing to identify tissue-specific biomarkers to achieve success. Using functional metrics provides powerful clinical relevancy for future predictive tools of cancer metastasis.</p>","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microneedle arrays coated with Middle East respiratory syndrome coronavirus DNA vaccine <i>via</i> electrospray deposition.","authors":"Sarah H Park, Isha R Shah, Nandita C Jhumur, Yaxin Mo, Shalaka Tendolkar, Emran O Lallow, Jerry W Shan, Jeffrey D Zahn, Joel N Maslow, Assimina A Pelegri, Hao Lin, David I Shreiber, Jonathan P Singer","doi":"10.1039/d4sm01322k","DOIUrl":"https://doi.org/10.1039/d4sm01322k","url":null,"abstract":"<p><p>Microneedle arrays have been shown to be a minimally invasive method of transdermal drug delivery. However, methods to coat these arrays often require a reservoir of the active ingredient, leading to unused and wasted material. Electrospray deposition is a targeted coating method that offers a competitive alternative for coating microneedles. By architecting the charge landscape of the setup, this technology can achieve coating deposition efficiencies nearing 100%, with little to no material wasted during the coating process. A Middle East respiratory syndrome coronavirus DNA vaccine was used as the model material to assess deposition efficiency as well as the efficacy of fragile biological materials subjected to electrospray deposition. Trehalose and polystyrene-<i>block</i>-polyacrylic acid were used as excipients to encourage coating dispersion. These coatings were inserted into Sprague Dawley rats where the antigen was subsequently detected and located using immunohistochemistry. Both coatings, with and without excipients, showed that protein expression is achieved after the vaccine is subjected to electrospray, however, the presence of excipients qualitatively leads to a more disperse diffusion profile. Further, this work demonstrates the capability of electrospray deposition as a highly efficient method to coat microneedles for transdermal drug delivery.</p>","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Review of MXene synthesis and applications in electromagnetic shielding","authors":"Yao Gan and Yuzhu Xiong","doi":"10.1039/D4RA08030K","DOIUrl":"https://doi.org/10.1039/D4RA08030K","url":null,"abstract":"<p >With the ongoing advancements in wireless communication and electronic technology, the issue of electromagnetic radiation (EMR) pollution has become increasingly significant. Consequently, developing materials to mitigate EMR pollution is essential. The utility of 2D MXene (Ti<small>₃</small>C<small>₂</small>T<small>_<em>x</em></small>) for electromagnetic interference (EMI) shielding was initially reported in 2016. Since then, MXenes have garnered substantial interest from the scientific community owing to their excellent metallic conductivity, low density, expansive specific surface area, and tunable interlayer spacing. In recent years, MXenes have demonstrated considerable promise in EMI shielding applications. This paper aims to examine the structural and chemical properties of MXenes, the methodologies for their synthesis, and summarize the advancements in MXene-based EMI shielding composites, highlighting their performance benefits. Additionally, this review will discuss the prospective developments in MXene-based materials for EMI shielding.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 12","pages":" 9555-9568"},"PeriodicalIF":3.9,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ra/d4ra08030k?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143716611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the mechanical and chemical properties of bitumen fractionation via time efficient chromatography techniques","authors":"Brittany Hallmark-Haack, Joshua Middleton, Ana Luiza Rodrigues, Michael Forrester, R. Christopher Williams and Eric Cochran","doi":"10.1039/D4RA09045D","DOIUrl":"https://doi.org/10.1039/D4RA09045D","url":null,"abstract":"<p >Bitumen, a crucial component of asphalt pavements, exhibits complex chemical properties that influence its performance. Traditional methods for separating bitumen into saturate, aromatic, resin, and asphaltene (SARA) fractions often suffer from limitations such as low efficiency and insufficient sample recovery. Here, we present a novel approach using flash chromatography to address these challenges. Our automated technique offers rapid and efficient separation of bitumen into fractions, enabling comprehensive characterization. To identify the most suitable column for bitumen characterization, we tested four different commercial columns packed with various stationary phases. By analyzing the separated fractions using analytical chemistry techniques and rheology testing, we demonstrated that each column type exhibits unique separation capabilities. Among the tested columns, the C18 column proved to be particularly valuable for obtaining comprehensive insights into the overall molecular structure and properties of bitumen. This research contributes to a deeper understanding of bitumen's molecular structure and its potential for developing higher-performing and longer-lasting asphalt pavements.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 13","pages":" 9594-9604"},"PeriodicalIF":3.9,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ra/d4ra09045d?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143726602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heterointerface engineering of vanadium oxide/cobalt nitride as efficient electrocatalysts for alkaline overall water splitting.","authors":"Tengfei Xu, Zhaohui Lu, Lan Yu, Wen Xin, Jie Sun, Haoze Zhou, Yanqing Jiao, Xiuwen Wang, Chunmei Lv","doi":"10.1039/d5cc01549a","DOIUrl":"https://doi.org/10.1039/d5cc01549a","url":null,"abstract":"<p><p>A triangular plate-shaped vanadium oxide/cobalt nitride (VO/CoN) heterostructure was constructed and used as an effective bifunctional electrocatalyst for alkaline water electrolysis. The VO/CoN-based electrolyzer exhibits a low cell voltage of 1.587 V at 10 mA cm^-2 and presents remarkable stability over 100 h of operation.</p>","PeriodicalId":67,"journal":{"name":"Chemical Communications","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unraveling the role of superoxide radicals in CdS quantum dot instability.","authors":"Miaoli Gu, Xianglin Xiang, Bei Cheng, Jiaguo Yu, Liuyang Zhang","doi":"10.1039/d5cc00433k","DOIUrl":"https://doi.org/10.1039/d5cc00433k","url":null,"abstract":"<p><p>Photocorrosion hinders CdS development, this study shows that after 2 hours of irradiation in oxygen, H₂O₂ yield of CdS reached 1.4 mmol g^-1, while it was nearly undetectable under nitrogen. Capture experiments and electron paramagnetic resonance confirm that O₂ acts as an electron acceptor, forming radicals that oxidize and deactivate CdS.</p>","PeriodicalId":67,"journal":{"name":"Chemical Communications","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis, photochromic properties, and bioactivity of spiropyrans with electron-donating/withdrawing substituents on indoline and [2<i>H</i>]-chromene rings.","authors":"Abir Kayal, Navjot Kaur, Mrinmoy De","doi":"10.1039/d5ob00033e","DOIUrl":"https://doi.org/10.1039/d5ob00033e","url":null,"abstract":"<p><p>Photochromic molecules from the spiropyran family are renowned for their ability to undergo light-induced interconversion between a colorless spiro form and a colored merocyanine form. The photoswitching behavior of various spiropyrans has been explored earlier but the influence of electron-donating and electron-withdrawing groups on the indoline and [2<i>H</i>]-chromene rings remains unexplored. In this work, we synthesized four distinct photochromic spiropyran molecules featuring all possible combinations of electronic effects. Their photoswitching activity and switching kinetics were systematically analyzed using spectroscopic and kinetic techniques. Furthermore, the antibacterial properties of these spiropyran derivatives were evaluated to uncover potential structure-activity relationships. This study provides important insights into the design of spiropyrans with customized photochromic properties and associated bioactivity.</p>","PeriodicalId":96,"journal":{"name":"Organic & Biomolecular Chemistry","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Highly selective electrocatalytic reduction of nitrate to ammonia over a copper–cobalt bimetallic catalyst†","authors":"Daopeng Li, Shengbo Zhang, Zhixian Mao, Min Liu, Kui Hu, Dongnan Zhao, Zhengguo Qv, Li Zhou and Tongfei Shi","doi":"10.1039/D5RA00860C","DOIUrl":"https://doi.org/10.1039/D5RA00860C","url":null,"abstract":"<p >The electrocatalytic nitrate reduction reaction (NitRR) is a promising alternative to the traditional Haber–Bosch process. However, the competitive hydrogen evolution reaction results in poor NH<small>₃</small> selectivity (<em>S</em><small>_NH3</small>). Here, a Cu–Co bimetallic catalyst supported on biomass-derived porous carbon (Cu–Co/BPC) is designed and synthesized. Interestingly, the catalyst presents a high NH<small>₃</small> yield rate of 9114.1 ± 244.8 μg h<small>⁻¹</small> cm<small>⁻²</small> at −1.4 V (<em>vs.</em> RHE) and a high faradaic efficiency (FE) of 84.5 ± 1.6% at −1.0 V (<em>vs.</em> RHE). Notably, the <em>S</em><small>_{NH<small>₃</small>}</small> of Cu–Co/BPC catalyst is kept above 94.2% under a broad range from −1.0 to −1.4 V (<em>vs.</em> RHE), indicating the high NitRR-to-NH<small>₃</small> selectivity of Cu–Co/BPC. The combination of <em>in situ</em> characterization and experimental results indicates that the electron transfer occurs between Cu and Co, and many active sites are generated for adsorption and activation of N<img>O double bonds, and hydrogenation reactions occur with adjacent H protons to improve the selectivity of NH<small>₃</small>.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 12","pages":" 9461-9466"},"PeriodicalIF":3.9,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ra/d5ra00860c?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143716605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}