BioethicsPub Date : 2025-02-01Epub Date: 2024-11-04DOI: 10.1111/bioe.13375
Christopher Bobier
{"title":"Ethical xenotransplant research on human brain-dead decedents.","authors":"Christopher Bobier","doi":"10.1111/bioe.13375","DOIUrl":"10.1111/bioe.13375","url":null,"abstract":"<p><p>Can it be ethical to conduct xenotransplant research on a human brain-dead decedent (HB-DD) whose organs could otherwise be given to persons in need? The ethical consensus is that it is better to save existing persons via organ donation than to devote a HB-DD to research that will not directly benefit anyone. I argue otherwise. Given how rapidly xenotransplant research is progressing, and its clinical promise in the next couple of years or decades, I argue that it can be ethical to conduct xenotransplant research on a HB-DD whose organs could otherwise be given to individuals in need.</p>","PeriodicalId":55379,"journal":{"name":"Bioethics","volume":" ","pages":"178-186"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142577194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioethicsPub Date : 2025-02-01Epub Date: 2024-10-03DOI: 10.1111/bioe.13356
Bridget Pratt
{"title":"Addressing the COVID-induced healthcare backlog: How can we balance the interests of people and nature?","authors":"Bridget Pratt","doi":"10.1111/bioe.13356","DOIUrl":"10.1111/bioe.13356","url":null,"abstract":"<p><p>The COVID-19 pandemic created healthcare backlogs of routine primary and preventive care, elective procedures, dental care, and mental healthcare appointments across the world. So far, governments are responding by enacting pandemic recovery policies that expand their healthcare sector activity, without much, if any, consideration of its effects on the environmental crisis that is (among other things) worsening human health and health equity. This paper argues that, as a matter of health and social justice, governments have an ethical responsibility to equitably reduce the backlog with minimal environmental damage. To do so, a first key action is to give priority to policy options that minimise negative human impacts on the environment. Yet these policies alone will not be sufficient to address the backlog, particularly in relation to elective procedures. The paper therefore contends that a second key action for governments is to enact the policy options that are best able to equitably reduce the remainder of the backlog, while accelerating the transition to sustainable health care in ways that are best able to reduce the specific environmental costs of those policy options. It concludes by considering whether limits apply to governments' ethical responsibilities that ultimately mean accelerating the transition to sustainable health care is not required when addressing the backlog.</p>","PeriodicalId":55379,"journal":{"name":"Bioethics","volume":" ","pages":"195-204"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioethicsPub Date : 2025-02-01Epub Date: 2024-10-30DOI: 10.1111/bioe.13365
Stephen R Milford
{"title":"Accuracy is inaccurate: Why a focus on diagnostic accuracy for medical chatbot AIs will not lead to improved health outcomes.","authors":"Stephen R Milford","doi":"10.1111/bioe.13365","DOIUrl":"10.1111/bioe.13365","url":null,"abstract":"<p><p>Since its launch in November 2022, ChatGPT has become a global phenomenon, sparking widespread public interest in chatbot artificial intelligences (AIs) generally. While not approved for medical use, it is capable of passing all three United States medical licensing exams and offers diagnostic accuracy comparable to a human doctor. It seems inevitable that it, and tools like it, are and will be used by the general public to provide medical diagnostic information or treatment plans. Before we are taken in by the promise of a golden age for chatbot medical AIs, it would be wise to consider the implications of using these tools as either supplements to, or substitutes for, human doctors. With the rise of publicly available chatbot AIs, there has been a keen focus on research into the diagnostic accuracy of these tools. This, however, has left a notable gap in our understanding of the implications for health outcomes of these tools. Diagnosis accuracy is only part of good health care. For example, crucial to positive health outcomes is the doctor-patient relationship. This paper challenges the recent focus on diagnostic accuracy by drawing attention to the causal relationship between doctor-patient relationships and health outcomes arguing that chatbot AIs may even hinder outcomes in numerous ways including subtracting the elements of perception and observation that are crucial to clinical consultations. The paper offers brief suggestions to improve chatbot medical AIs so as to positively impact health outcomes.</p>","PeriodicalId":55379,"journal":{"name":"Bioethics","volume":" ","pages":"163-169"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142549084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction.","authors":"","doi":"10.1080/08989621.2024.2334736","DOIUrl":"10.1080/08989621.2024.2334736","url":null,"abstract":"","PeriodicalId":50927,"journal":{"name":"Accountability in Research-Policies and Quality Assurance","volume":" ","pages":"i"},"PeriodicalIF":2.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140872704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Incorporating implicit bias into research integrity education: Response to 'Why and how to incorporate issues of race/ethnicity and gender in research integrity education'.","authors":"Shivatej Dubbaka","doi":"10.1080/08989621.2023.2247974","DOIUrl":"10.1080/08989621.2023.2247974","url":null,"abstract":"<p><p>This letter focuses on the importance of incorporating implicit bias into research integrity education, and the significant impact it can have on creating an equitable research environment.</p>","PeriodicalId":50927,"journal":{"name":"Accountability in Research-Policies and Quality Assurance","volume":" ","pages":"193-194"},"PeriodicalIF":2.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10030503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Extent of publishing in predatory journals by academics in higher education institutions in Zimbabwe: A case study of a university.","authors":"R M Jingura, J Chigwada, T Diver, D Shangwa","doi":"10.1080/08989621.2023.2256672","DOIUrl":"10.1080/08989621.2023.2256672","url":null,"abstract":"<p><p>The publish or perish concept requires academics to ensure that they take part in research and publish the research results in academic journals. The emergency of predatory publishers has led to negativity in the scholarly publishing process. Some researchers are unaware that some publishers are unethical. A study was conducted to determine the extent of predatory publishing in Zimbabwe among academics. A survey was carried out using a multi-method approach at a public university in Zimbabwe. Articles published between 2012 and 2022 were retrieved using the Harzing publish or perish software. In total, 977 articles were retrieved, and after data cleaning using Open Refine, 357 records were analyzed using the journal evaluation rubric and scoring sheet to note the extent of predatory publishing among the various schools. The articles were then classified into 3 sections i.e., predatory, not predatory, and borderline. The findings revealed that predatory publishing is prevalent in the social sciences. The authors recommend the importance of training to create awareness about the dangers of predatory publishing and how to avoid them to improve the scholarly output of the institution, which is key to university ranking.</p>","PeriodicalId":50927,"journal":{"name":"Accountability in Research-Policies and Quality Assurance","volume":" ","pages":"143-157"},"PeriodicalIF":2.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10205928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Are there accurate and legitimate ways to machine-quantify predatoriness, or an urgent need for an automated online tool?","authors":"Bor Luen Tang","doi":"10.1080/08989621.2023.2253425","DOIUrl":"10.1080/08989621.2023.2253425","url":null,"abstract":"<p><p>Yamada and Teixeira da Silva voiced valid concerns with the inadequacies of an online machine learning-based tool to detect predatory journals, and stressed on the urgent need for an automated, open, online-based semi-quantitative system that measures \"predatoriness\". We agree that the said machine learning-based tool lacks accuracy in its demarcation and identification of journals outside those already found within existing black and white lists, and that its use could have undesirable impact on the community. We note further that the key characteristic of journals being predatory, namely a lack of stringent peer review, would normally not have the visibility necessary for training and informing machine learning-based online tools. This, together with the gray zone of inadequate scholarly practice and the plurality in authors' perception of predatoriness, makes it desirable for any machine-based, quantitative assessment to be complemented or moderated by a community-based, qualitative assessment that would do more justice to both journals and authors.</p>","PeriodicalId":50927,"journal":{"name":"Accountability in Research-Policies and Quality Assurance","volume":" ","pages":"182-187"},"PeriodicalIF":2.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10474862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioethicsPub Date : 2025-02-01Epub Date: 2024-10-03DOI: 10.1111/bioe.13360
Kenneth T Moore
{"title":"Clinical research vehicles as a modality for medical research education and conduct of decentralized trials, supporting justice, equity, and diversity in research.","authors":"Kenneth T Moore","doi":"10.1111/bioe.13360","DOIUrl":"10.1111/bioe.13360","url":null,"abstract":"<p><p>Current clinical research lacks diversity in those that participate. This lack of diversity is concerning given its importance for successful drug development. The frequency and severity of many diseases, along with the pharmacological properties of therapies, can display significant differences based on patient diversity. A clinical trial population that is more reflective of these differences will help researchers better understand the therapeutic profile of the treatment and provide generalizable knowledge to the medical community. The advent of decentralized clinical trial designs is meant to help address this lack of diversity by using portable digital health technologies and virtual interactions to enhance clinical trial access and broaden participation. By leveraging these technologies, trial conduct can occur at locations other than traditional research sites. This shift in trial location may help address some of the logistical, educational, engagement, and trust barriers that have historically prevented enrollment of diverse populations. However, these types of trials still have limitations. Ethical concerns around justice, equity, and diversity will still exist with decentralized clinical trials, which could be mediated using clinical research vehicles. When utilized, this modality may enhance the scientific design and conduct of clinical trials and better follow these ethical principles. These enhancements and improved ethical direction could be accomplished through increasing community involvement, improving health literacy, supporting more diverse trial sites, creating community-based research footholds, fostering connections with researchers, limiting technical challenges, and preventing data security issues.</p>","PeriodicalId":55379,"journal":{"name":"Bioethics","volume":" ","pages":"213-220"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioethicsPub Date : 2025-02-01Epub Date: 2024-11-10DOI: 10.1111/bioe.13371
Niñoval F Pacaol, Alderf Anthonio T Cabero, Britten Izzy A Ragonot, Alysha Mae A Cajes, Princess Zuemaeyah J Sarsalejo, Ybrahim Jamil B Monge, Jacob Razel D Villaluz, Abishai Andea A Adorna
{"title":"Family-making avec emerging technologies and/or non-human animals.","authors":"Niñoval F Pacaol, Alderf Anthonio T Cabero, Britten Izzy A Ragonot, Alysha Mae A Cajes, Princess Zuemaeyah J Sarsalejo, Ybrahim Jamil B Monge, Jacob Razel D Villaluz, Abishai Andea A Adorna","doi":"10.1111/bioe.13371","DOIUrl":"10.1111/bioe.13371","url":null,"abstract":"","PeriodicalId":55379,"journal":{"name":"Bioethics","volume":" ","pages":"226-227"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}