IF 2 3区农林科学

Animal Biotechnology Pub Date : 2027-12-01 Epub Date: 2026-10-22 DOI: 10.1080/10495398.2026.2743468

Xiaonan Zhou, Zhiyan Zhao, Lei Zhao, Qiyu Diao, Lifeng Dong, Xiaolong Kang

{"title":"Effects of xylooligosaccharide supplementation on methane emissions, rumen microbiome, and serum metabolome in lactating Jersey cows.","authors":"Xiaonan Zhou, Zhiyan Zhao, Lei Zhao, Qiyu Diao, Lifeng Dong, Xiaolong Kang","doi":"10.1080/10495398.2026.2743468","DOIUrl":"10.1080/10495398.2026.2743468","url":null,"abstract":"Xylooligosaccharides (XOS) are recognized as effective prebiotics that can mitigate methane (CH4) emissions. However, the specific relationship between the effects of XOS on CH4 emissions and alterations in the ruminal microbiota and their metabolites remains unclear. To investigate the relationship between XOS and CH4 emissions, 48 Jersey cows were randomly divided into two groups: the XOS group (group T) and the control group (group C). Group T received 25 g/d of XOS, while group C received 0 g/d of XOS added to the basal diet. Three randomly selected cows from each group, exhibiting consistent milk production and lactation stage, were analyzed for CH4 emissions detection, 16S rRNA sequencing, and untargeted metabolomics analysis. The addition of XOS significantly reduced CH4 emissions and increased both the number of observed species and the abundance-based coverage estimator (ACE) index of ruminal microbiota compared to group C. Sixteen differential metabolites were identified between the two groups; these differential metabolites were correlated with microbiota, including Chloroflexi, Acidobacteriota, and Succiniclasticum. The study suggests that XOS may regulate ruminant CH4 emissions by influencing the microbiota, thereby providing a rationale for CH4 control.","PeriodicalId":7836,"journal":{"name":"Animal Biotechnology","volume":"38 1","pages":"2743468"},"PeriodicalIF":2.0,"publicationDate":"2027-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13715329/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149236637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Isolation and characterization of rabbit intramuscular preadipocytes: Establishing a foundation for studies of intramuscular fat metabolism. 兔肌内前脂肪细胞的分离与表征：为肌内脂肪代谢研究奠定基础。

IF 2 3区农林科学

Animal Biotechnology Pub Date : 2027-12-01 Epub Date: 2026-10-21 DOI: 10.1080/10495398.2026.2740386

Ifeanyi S Ahamba, Guohua Song, Lionel Kinkpe, Qianting Duan, Naqash Goswami, Zhuoya Jin, Jie Wu, Xianggui Dong, Zhanjun Ren

{"title":"Isolation and characterization of rabbit intramuscular preadipocytes: Establishing a foundation for studies of intramuscular fat metabolism.","authors":"Ifeanyi S Ahamba, Guohua Song, Lionel Kinkpe, Qianting Duan, Naqash Goswami, Zhuoya Jin, Jie Wu, Xianggui Dong, Zhanjun Ren","doi":"10.1080/10495398.2026.2740386","DOIUrl":"10.1080/10495398.2026.2740386","url":null,"abstract":"Intramuscular fat (IMF) significantly influences meat quality, affecting flavor, tenderness, and juiciness. Despite extensive research on livestock such as cattle and pigs, the regulation of IMF in rabbits remains poorly understood. This study establishes a standardized in vitro method for isolating and characterizing intramuscular preadipocytes from the longissimus dorsi muscle of 3-day-old Hycole rabbits using enzymatic digestion and differential centrifugation. Three-day-old neonates were selected for initial protocol development due to their higher progenitor cell abundance and tissue accessibility, which facilitates method optimization and ensures consistent cell yields. Isolated cells displayed typical preadipocyte morphology and expressed key markers, including PREF-1, PPARγ, and Leptin, confirmed by RT-qPCR and immunofluorescence. Upon adipogenic induction, cells exhibited progressive lipid accumulation, as indicated by Oil Red O staining, and showed upregulated expression of PPARG, C/EBPa, and FABP4, confirming their differentiation potential. This study establishes a comprehensive protocol for isolating rabbit intramuscular preadipocytes, providing a foundational tool for investigating the molecular mechanisms of adipogenesis in lagomorphs. The model supports future studies on genetic and nutritional strategies to enhance rabbit meat quality while preserving its lean characteristics.","PeriodicalId":7836,"journal":{"name":"Animal Biotechnology","volume":"38 1","pages":"2740386"},"PeriodicalIF":2.0,"publicationDate":"2027-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13700512/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149236613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

AI-assisted post-mortem classification of vehicle trauma in free-roaming cats using transformer-based large language models. 使用基于变压器的大型语言模型对自由漫游猫的车辆创伤进行人工智能辅助死后分类。

IF 3.9 2区农林科学

Veterinary Quarterly Pub Date : 2026-12-31 Epub Date: 2026-08-03 DOI: 10.1080/01652176.2026.2705200

Hyunji Jo, Ji-Su Baek, Donghee Lee, Ah-Young Kim, Kyunghyun Lee, Bok-Kyung Ku, Adam W Stern, Jong Hyuk Kim

{"title":"AI-assisted post-mortem classification of vehicle trauma in free-roaming cats using transformer-based large language models.","authors":"Hyunji Jo, Ji-Su Baek, Donghee Lee, Ah-Young Kim, Kyunghyun Lee, Bok-Kyung Ku, Adam W Stern, Jong Hyuk Kim","doi":"10.1080/01652176.2026.2705200","DOIUrl":"10.1080/01652176.2026.2705200","url":null,"abstract":"Veterinary forensic science is a specialized discipline that investigates non-natural animal deaths and injuries. Determining the cause of death in free-roaming cats often presents challenges due to underdeveloped pattern recognition methods and the intricate interplay of events and contributing factors. The integration of natural language processing into forensic investigations may offer potential for the computerized automation of document analysis, with the goal of supporting investigational decision-making. The objective of this study was to develop an AI framework leveraging a transformer-based large language model (LLM) to classify veterinary forensic autopsy reports derived from 271 feline autopsies and to identify the causes of death. We first identified discriminative lexical patterns between vehicular trauma (VT; n = 111) and non-VT cases (n = 160) using Term Frequency-Inverse Document Frequency analysis. The best-performing model, based on Clinical-Longformer, achieved an accuracy of 0.945, precision of 0.885, recall of 1.000, F1 score of 0.939, and AUC-ROC of 0.950. Model interpretability using Integrated Gradients revealed that VT cases were characterized by terms associated with traumatic physical injuries, whereas non-VT cases exhibited a broader range of diagnostic descriptions. These findings demonstrate the feasibility of applying LLMs to veterinary forensic pathological texts and underscore the importance of domain-specific token interpretation for model explainability.","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"46 1","pages":"2705200"},"PeriodicalIF":3.9,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13435293/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148664953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Canine brain imaging with a new low-field portable (0.05 T) MRI scanner: a pilot in vivo comparison to conventional 1.5 T. 犬脑成像与新型低场便携式（0.05 T） MRI扫描仪：与常规1.5 T的试验对比。

IF 3.9 2区农林科学

Veterinary Quarterly Pub Date : 2026-12-31 Epub Date: 2026-07-14 DOI: 10.1080/01652176.2026.2696026

Elisabeth Maria Burgers, Samantha Miles, Ruben van den Broek, Chloé Najac, Beatrice Lena, Thomas O'Reilly, Andrew Webb, Stefanie Veraa

{"title":"Canine brain imaging with a new low-field portable (0.05 T) MRI scanner: a pilot in vivo comparison to conventional 1.5 T.","authors":"Elisabeth Maria Burgers, Samantha Miles, Ruben van den Broek, Chloé Najac, Beatrice Lena, Thomas O'Reilly, Andrew Webb, Stefanie Veraa","doi":"10.1080/01652176.2026.2696026","DOIUrl":"10.1080/01652176.2026.2696026","url":null,"abstract":"Prohibitive costs associated with high-field MRI systems have resulted in reduced access in resource-limited areas with consequential healthcare inequities. This has renewed interest in purposefully designed low-field (LF) systems that, despite inherently lower signal-to-noise ratios, have advantages in terms of cost, portability, and accessibility. This pilot study successfully translated a previously developed LF (0.05 T) MRI canine cadaver brain protocol for in vivo application and compared the acquired images with paired 1.5 T images from 21 different canine patients. The visibility of 15 anatomic features was ordinarily scored (scale 1-3) on transverse T1-weighted post-contrast (21/21 patients) and T2-weighted (17/21 patients) sequences. Lateral ventricles were easily visualized (89.3%-100% scored 3/3) across all sequence‒system combinations, with T2-weighted sequences also providing good identification of the mesencephalic aqueduct (56.3%-100%), fourth ventricle (77.1%-100%), and thalamus (68.8%-100%). Absolute visual grading characteristics (VGC) analysis confirmed comparable performance of the LF system to the 1.5 T MRI for these features, a particularly relevant finding given the system's originally intended application for pediatric hydrocephalus neuroimaging in resource-limited areas. This study represents the first in vivo usage and evaluation of a 0.05 T MRI in a clinical veterinary context.","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"46 1","pages":"2696026"},"PeriodicalIF":3.9,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13371494/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148438286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Structural characterization of PAMK and its protective effect against thymic necroptosis in goslings. PAMK的结构特征及其对雏鹅胸腺坏死的保护作用。

IF 3.9 2区农林科学

Veterinary Quarterly Pub Date : 2026-12-31 Epub Date: 2026-09-01 DOI: 10.1080/01652176.2026.2695104

Wanyan Li, Baili Lu, Xiangying Zhou, Shirou Pan, Junhao Wei, Bingxin Li, Nan Cao, Yunmao Huang, Wenjun Liu, Xinliang Fu, Yunbo Tian, Danning Xu

{"title":"Structural characterization of PAMK and its protective effect against thymic necroptosis in goslings.","authors":"Wanyan Li, Baili Lu, Xiangying Zhou, Shirou Pan, Junhao Wei, Bingxin Li, Nan Cao, Yunmao Huang, Wenjun Liu, Xinliang Fu, Yunbo Tian, Danning Xu","doi":"10.1080/01652176.2026.2695104","DOIUrl":"10.1080/01652176.2026.2695104","url":null,"abstract":"PAMK are heterogeneous glycans with immunomodulatory potential, but their structural basis and mechanisms in regulating thymic injury remain unclear. Structural characterization revealed that PAMK is mainly composed of arabinose, galactose, rhamnose, galacturonic acid, and glucose, featuring a dominant backbone consisting of →4)-α-D-GalpA-(1→, →4)-β-D-Galp-(1→, →2)-α-L-Rhap-(1→, and →3,4)-α-D-GalpA-(1→ with highly branched side chains. This complex structure provides the biochemical foundation for its bioactivity. To explore its immunoprotective effects, we established a CTX-induced thymic necroptosis model in goslings. CTX markedly disrupted cytokine profiles and activated necroptosis signaling, accompanied by downregulation of novel-miR-2 and upregulation of TRADD and MLKL. Dietary PAMK supplementation significantly restored cytokine homeostasis and inhibited necroptosis pathway activation. Mechanistically, PAMK upregulated novel-miR-2, which negatively regulated TRADD and MLKL expression, thereby attenuating necroptosis signaling. Overexpression of novel-miR-2 suppressed TRADD/MLKL-mediated necroptosis, whereas its inhibition produced the opposite effect. Furthermore, PAMK mitigated oxidative stress and necroptotic cell death induced by TRADD and MLKL overexpression. Collectively, our findings demonstrate that the defined structural features of PAMK underpin its ability to protect against CTX-induced thymic necroptosis by upregulating novel-miR-2 and suppressing the TRADD/MLKL axis. This work links PAMK's composition to its immunoprotective function and highlights its potential as a safe immunoregulatory agent in poultry.","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"46 1","pages":"2695104"},"PeriodicalIF":3.9,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13537054/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148867718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rethinking dog stress behaviours: contextual and physiological insights from the attachment framework. 重新思考狗的压力行为：来自依恋框架的语境和生理见解。

IF 3.9 2区农林科学

Veterinary Quarterly Pub Date : 2026-12-31 Epub Date: 2026-08-21 DOI: 10.1080/01652176.2026.2682284

Giacomo Riggio, Carmen Borrelli, Durmus Atilgan, Giulia Russo, Silvana Diverio, Chiara Mariti

{"title":"Rethinking dog stress behaviours: contextual and physiological insights from the attachment framework.","authors":"Giacomo Riggio, Carmen Borrelli, Durmus Atilgan, Giulia Russo, Silvana Diverio, Chiara Mariti","doi":"10.1080/01652176.2026.2682284","DOIUrl":"10.1080/01652176.2026.2682284","url":null,"abstract":"While dogs' behavioural indicators of psychological stress are widely used, their function as reliable stress markers remains debated. Using the Strange Situation Procedure (SSP) as a social-stress paradigm, we evaluated contextual correlates of dog behaviours to explore their validity as stress indicators. In 64 dogs, behaviours commonly used as stress markers were video-coded and analysed via GLMMs to investigate differences across test episodes and attachment styles (secure, anxious, avoidant), while salivary cortisol, oxytocin, and rectal temperature provided a physiological framework. Episode had significant effects on shaking (p < 0.05), lip-licking (p < 0.001), paw-lifting (p < 0.001), whining (p < 0.001), head-turning (p < 0.001), sniffing the door (p < 0.001), and locomotion (p < 0.001), while attachment style significantly affected head-turning only (p = 0.004). Our findings suggest that the observed behaviours were not expressed linearly in relation to expected stress levels across the SSP episodes. This lack of linearity, combined with the divergent physiological correlates found across attachment groups-for instance, oxytocin correlated positively with lip-licking in securely attached dogs (p < 0.05), but negatively in anxious ones (p < 0.05) -, suggests that these behaviours do not function as simple stress indicators. Rather, their meaning appears to be contingent upon the individual's internal state and the socio-environmental context. We discuss our results in light of an alternative semiotic interpretative framework.","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"46 1","pages":"2682284"},"PeriodicalIF":3.9,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13501743/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148801318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Monitoring horse behaviour with deep learning models. 用深度学习模型监测马的行为。

IF 3.9 2区农林科学

Veterinary Quarterly Pub Date : 2026-12-31 Epub Date: 2026-04-28 DOI: 10.1080/01652176.2026.2665442

Claudia Giannone, Chiara Maccario, Emanuela Dalla Costa, Elie Atallah, Marco Bovo

引用次数: 0

Integrating physiological indicators and Precision Livestock Farming to support European animal welfare frameworks: a systematic review. 整合生理指标和精准畜牧业以支持欧洲动物福利框架：系统回顾。

IF 3.9 2区农林科学

Veterinary Quarterly Pub Date : 2026-12-31 Epub Date: 2026-11-04 DOI: 10.1080/01652176.2026.2739038

Giulia Pastorelli, Rita Iacono, Alda Quattrone, Giacomo Contò

{"title":"Integrating physiological indicators and Precision Livestock Farming to support European animal welfare frameworks: a systematic review.","authors":"Giulia Pastorelli, Rita Iacono, Alda Quattrone, Giacomo Contò","doi":"10.1080/01652176.2026.2739038","DOIUrl":"10.1080/01652176.2026.2739038","url":null,"abstract":"Animal welfare assessment in livestock production is increasingly supported by Precision Livestock Farming (PLF) technologies integrated with physiological monitoring. This Scopus-based systematic literature review, conducted according to PRISMA guidelines and synthesised using a narrative approach, examined physiological parameters relevant to animal welfare assessment and their integration into PLF across major livestock species, including cattle, pigs, poultry, sheep, and goats. Following the screening and eligibility assessment, 144 studies were selected from an initial dataset of 1386 records. Body surface temperature, heart rate, and respiratory rate were the most frequently investigated physiological parameters, while computer vision, wearable sensors, environmental sensing, and machine learning were the predominant technologies enabling continuous, non-invasive monitoring. The reviewed studies primarily addressed animal-based welfare indicators within European welfare assessment frameworks, whereas resource- and management-based indicators were comparatively underrepresented. No studies explicitly investigated antimicrobial use or the human-animal relationship using PLF technologies, highlighting important research gaps. Overall, the evidence indicates that physiological parameters provide complementary biological information that enhances the interpretation of animal-based welfare indicators, particularly when integrated with behavioural and environmental monitoring. Future research should prioritise multimodal approaches integrating physiological, behavioural, environmental, and management-related data to support more comprehensive and operationally feasible animal welfare assessment.","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"46 1","pages":"2739038"},"PeriodicalIF":3.9,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149335969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hormonal and metabolic adaptations in Omega-3-supplemented rabbit does during their first reproductive cycle. 补充omega -3的兔在其第一个生殖周期中的激素和代谢适应。

IF 3.9 2区农林科学

Veterinary Quarterly Pub Date : 2026-12-31 Epub Date: 2026-10-29 DOI: 10.1080/01652176.2026.2749322

Alda Quattrone, Nour Elhouda Fehri, Olimpia Barbato, Giovanni Ricci, Daniele Vigo, Luigj Turmalaj, Majlind Sulçe, Marta Castrica, Maria Laura Marongiu, Alessandro Dal Bosco, Bayrem Jemmali, Gerald Muça, Gabriele Brecchia, Giulio Curone, Laura Menchetti

{"title":"Hormonal and metabolic adaptations in Omega-3-supplemented rabbit does during their first reproductive cycle.","authors":"Alda Quattrone, Nour Elhouda Fehri, Olimpia Barbato, Giovanni Ricci, Daniele Vigo, Luigj Turmalaj, Majlind Sulçe, Marta Castrica, Maria Laura Marongiu, Alessandro Dal Bosco, Bayrem Jemmali, Gerald Muça, Gabriele Brecchia, Giulio Curone, Laura Menchetti","doi":"10.1080/01652176.2026.2749322","DOIUrl":"10.1080/01652176.2026.2749322","url":null,"abstract":"This study evaluated the effects of dietary n-3 polyunsaturated fatty acids (n-3 PUFA) supplementation on endocrine and metabolic profiles of forty-five nulliparous rabbit does during their first reproductive cycle. Animals were randomly assigned to one of three diets: control (CNT), 5% extruded linseed (L), and 5% extruded linseed plus 0.2% Padina pavonica extract (LPP). Blood was sampled at baseline, artificial insemination, parturition, mid-lactation, and weaning, to determine the concentrations of cortisol, insulin, leptin, thyroid hormones (T3, T4), glucose, and non-esterified fatty acids (NEFA). Reproductive stage significantly influenced endocrine and metabolic dynamics, with cortisol and NEFA peaking at parturition (p < 0.001). Supplemented groups, particularly LPP, showed higher T3 concentrations (p < 0.05) and T3/T4 ratios (p < 0.01). The L diet maintained higher insulin during lactation (p < 0.05), while LPP lowered leptin at parturition (p < 0.01) and NEFA at insemination (p < 0.01), indicating an early decrease in lipid mobilization. Multivariate analysis suggested that n-3 PUFA supplementation promoted an endocrine profile characterized by enhanced thyroid activity and reduced lipid mobilization, consistent with a potentially favorable metabolic shift. In conclusion, enriching diets with n-3 PUFA, especially linseed combined with Padina pavonica extract, represents a promising nutritional strategy to support rabbit does during the highly demanding phases of their first reproductive cycle.","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"46 1","pages":"2749322"},"PeriodicalIF":3.9,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13721818/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149301959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Photodynamic antimicrobial and antineoplastic therapy in veterinary medicine: current status, challenges, and perspectives. 兽医中的光动力抗微生物和抗肿瘤治疗：现状、挑战和前景。

IF 3.9 2区农林科学

Veterinary Quarterly Pub Date : 2026-12-31 Epub Date: 2026-08-16 DOI: 10.1080/01652176.2026.2713493

Jiaxu Lu, Shuyao Zhu, Aftab Shaukat, Shuhao Bian, Xiaoxuan Shi, Di Zhu, Jingyu Wang, Aoyun Li, Hongyu Dai, Fang Liu, Haiju Dong, Xiangqian Zhang

{"title":"Photodynamic antimicrobial and antineoplastic therapy in veterinary medicine: current status, challenges, and perspectives.","authors":"Jiaxu Lu, Shuyao Zhu, Aftab Shaukat, Shuhao Bian, Xiaoxuan Shi, Di Zhu, Jingyu Wang, Aoyun Li, Hongyu Dai, Fang Liu, Haiju Dong, Xiangqian Zhang","doi":"10.1080/01652176.2026.2713493","DOIUrl":"10.1080/01652176.2026.2713493","url":null,"abstract":"Significant causes of morbidity in veterinary medicine are tumourigenic diseases and pathogenic infections, which pose significant threats to animal health. Traditional methods for treating tumours and bacterial infections primarily involve chemotherapy and antibiotic therapy, both of which are associated with drug resistance and adverse effects. Photodynamic therapy (PDT) is gaining increasing interest in veterinary clinical practice because of its distinctive benefits such as spatiotemporal selectivity, low toxicity, fewer negative effects, and reduced risk of drug resistance. This review summarises the fundamental principles of PDT and its applications in combating tumours and microbial infections in veterinary practice involving companion animals, livestock, wildlife, and reptiles. It is worth noting that the existing clinical evidence is limited by very small sample sizes and the absence of comparator groups; however, these studies have provided a preliminary theoretical foundation and technical reference for further clinical development of PDT. Moreover, the opportunities and challenges associated with PDT in veterinary clinical practice are discussed herein.","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"46 1","pages":"2713493"},"PeriodicalIF":3.9,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13482929/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148764909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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