Archives of Insect Biochemistry and Physiology最新文献

A South African Scenario: Structure and Function of Peptides of the Adipokinetic Hormone Family of the Brown Locust, Locustana pardalina, and the Putative Role of These Peptides in Plague Management 南非情景：褐蝗脂肪动力激素家族多肽的结构和功能，以及这些多肽在鼠疫管理中的假定作用。

IF 1.9 4区农林科学

Archives of Insect Biochemistry and Physiology Pub Date : 2025-10-03 DOI: 10.1002/arch.70103

Gerd Gäde, Heather G. Marco

{"title":"A South African Scenario: Structure and Function of Peptides of the Adipokinetic Hormone Family of the Brown Locust, Locustana pardalina, and the Putative Role of These Peptides in Plague Management","authors":"Gerd Gäde, Heather G. Marco","doi":"10.1002/arch.70103","DOIUrl":"10.1002/arch.70103","url":null,"abstract":"The brown locust, Locustana pardalina, is a major agricultural pest in southern Africa during swarm formation. Like other locust species, L. pardalina has much higher carbohydrate concentrations in circulation than lipid; carbohydrates are predominantly used in the first minutes of flight and with sustained flight, the metabolic fuel switches to lipids mobilised from fat body stores. We isolated three peptides from the corpora cardiaca of the brown locust; through sequence elucidation by Edman degradation, mass spectrometry and chromatographic confirmation, we show that the brown locust has the same compliment of chemically isolated adipokinetic hormones (AKHs) as in Locusta migratoria: a decapeptide and two octapeptides; all increase the circulating lipid levels in locusts but not the carbohydrate concentration. During a rest period following flight, the carbohydrate levels in the haemolymph remained lower than before flight, whereas the lipid levels remained elevated. We show that the glycogen concentration in the fat body is significantly lowered after 1 h rest postflight and it is significantly increased in the flight muscles in this time. Thus, glycogen is mobilised from the fat body during the rest phase and transported as trehalose to the flight muscles and there, converted to glycogen, presumably to supply energy for a subsequent flight action. Finally, we discuss the molecular evolution of AKHs in Orthoptera and how two of the brown locust AKHs could serve as leads for developing peptidomimetics for combatting swarm outbreaks and reducing the need for harmful, indiscriminate chemical pesticides.","PeriodicalId":8281,"journal":{"name":"Archives of Insect Biochemistry and Physiology","volume":"120 2","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/arch.70103","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145211496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protease Dynamics: The Diversity and Plasticity in the Proteases of Insect Pest Chilo partellus in Response to Sorghum bicolor Genotypes 蛋白酶动态研究：高粱双色基因型对残叶螟蛋白酶多样性和可塑性的影响。

IF 1.9 4区农林科学

Archives of Insect Biochemistry and Physiology Pub Date : 2025-10-03 DOI: 10.1002/arch.70096

Surhud S. Sant, Javed A. Mulla, Vaijayanti A. Tamhane

{"title":"Protease Dynamics: The Diversity and Plasticity in the Proteases of Insect Pest Chilo partellus in Response to Sorghum bicolor Genotypes","authors":"Surhud S. Sant, Javed A. Mulla, Vaijayanti A. Tamhane","doi":"10.1002/arch.70096","DOIUrl":"10.1002/arch.70096","url":null,"abstract":"<div>\u0000 \u0000 The insect pest Chilo partellus (C. Swinhoe 1885), commonly known as the spotted stem borer, poses a significant threat to Sorghum bicolor (L. Moench 1794), a major cereal crop. This study investigates the complex interaction between C. partellus and different sorghum genotypes, with a focus on the contrasting effects on larval mass and mortality when reared on resistant versus susceptible sorghum varieties. Notably, larvae fed on susceptible sorghum exhibited enhanced growth performance. Our analysis revealed qualitative and quantitative differences in digestive protease expression in response to host plant genotype, with the highest overall protease activity observed in larvae fed on resistant sorghum. Furthermore, protease isoforms demonstrated distinct responses to synthetic non-host proteinaceous protease inhibitors, indicating variable inhibitor sensitivities. Transcriptomic analysis revealed a diverse array of hydrolase and protease genes expressed in C. partellus larvae reared on natural sorghum. The expression profiles of the newly identified chymotrypsins (CpaChy1-4) varied according to the resistance status of the host sorghum genotype. Phylogenetic analysis positioned these novel CpaChys within a clade closely related to chymotrypsins identified in Ostrinia nubilalis. In silico binding studies suggested that CpaChy1 and CpaChy2 are less likely to interact with sorghum-derived serine protease inhibitors compared to the other identified chymotrypsins. Unraveling the molecular mechanisms underlying these diet-specific protease adaptations in C. partellus is critical for advancing our understanding of the insect's ability to adapt to different host plant defenses.</div>","PeriodicalId":8281,"journal":{"name":"Archives of Insect Biochemistry and Physiology","volume":"120 2","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145211559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Histone Deacetylases Are Required for Female Reproduction and Embryonic Development in the Red Flour Beetle Tribolium castaneum. 红粉甲虫雌性生殖和胚胎发育需要组蛋白去乙酰化酶。

IF 1.9 4区农林科学

Archives of Insect Biochemistry and Physiology Pub Date : 2025-10-01 DOI: 10.1002/arch.70105

Karthi Sengodan, Subba Reddy Palli

引用次数: 0

Effects of Pesticides on Apis cerana From Passion Fruit in Hainan Island. 农药对海南岛百香果中华蜜蜂的影响。

IF 1.9 4区农林科学

Archives of Insect Biochemistry and Physiology Pub Date : 2025-10-01 DOI: 10.1002/arch.70097

Yuquan Wang, Zhiye Yao, Wenbo Dong, Wensu Han, Tianbin Wang, Chaozheng Wang, Fen Li, Shaoying Wu

{"title":"Effects of Pesticides on Apis cerana From Passion Fruit in Hainan Island.","authors":"Yuquan Wang, Zhiye Yao, Wenbo Dong, Wensu Han, Tianbin Wang, Chaozheng Wang, Fen Li, Shaoying Wu","doi":"10.1002/arch.70097","DOIUrl":"https://doi.org/10.1002/arch.70097","url":null,"abstract":"The tropical fruit passion fruit, which depends on insect pollinators such as the Apis cerana, is susceptible to risks associated with excessive pesticide application. These risks include detrimental effects on pollinating insects and the issue of pesticide residues. To quantify these impacts, a multidimensional experimental design was implemented: (1) Sampling entailed the collection of diverse samples (fruit, leaves, flowers, soil, honey, pollen, bees) from eight orchards spanning Hainan Island at four key time points, from preflowering to postpollination. (2) Residues of 12 targeted chemical substances, comprising neonicotinoids, organophosphorus, pyrethroid, and fungicides, were analyzed through liquid chromatography-mass spectrometry. (3) The acute contact toxicity of four neonicotinoid insecticides to Chinese honeybee workers was determined using the drop method, calculating the 48-h median lethal dose (LD50). (4) Dietary intake risks for passion fruit and honey were evaluated via the target hazard quotient (THQ) and risk quotient (RQ) models, whereas ecological risks to bees were assessed through the hazard quotient (HQ) and spray exposure risk quotient (RQsp). The results revealed pesticide detection rates ranging from 1.41% to 70.59%, with the highest total detection rate in the Baoting region. Thiamethoxam was the most prevalent residue, particularly during the initial phase of pollination. No residues were detected in honey, and flupyradifurone was absent across all samples. The dietary risk was deemed acceptable; however, pesticide use had a discernible impact on bee colonies, particularly in the Wuzhishan region. All four neonicotinoid insecticides exhibited high toxicity to Chinese honeybees, with thiamethoxam being the most potent. The study advises judicious pesticide usage during the flowering period to preserve bee pollination.","PeriodicalId":8281,"journal":{"name":"Archives of Insect Biochemistry and Physiology","volume":"120 2","pages":"e70097"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CYP450 Gene Cloning and Expression Patterns Induced by Two Neonicotinoid Insecticides in Megalurothrips usitatus. 两种新烟碱类杀虫剂诱导巨尿蓟马CYP450基因的克隆及表达模式

IF 1.9 4区农林科学

Archives of Insect Biochemistry and Physiology Pub Date : 2025-10-01 DOI: 10.1002/arch.70102

Tianbao Huang, Wenbo Dong, Jianwen Chen, Haifeng Jin, Wenjin Liu, Fen Li, Shaoying Wu

{"title":"CYP450 Gene Cloning and Expression Patterns Induced by Two Neonicotinoid Insecticides in Megalurothrips usitatus.","authors":"Tianbao Huang, Wenbo Dong, Jianwen Chen, Haifeng Jin, Wenjin Liu, Fen Li, Shaoying Wu","doi":"10.1002/arch.70102","DOIUrl":"https://doi.org/10.1002/arch.70102","url":null,"abstract":"Cytochrome P450 (P450s) play a crucial role in insecticide detoxification and metabolic resistance in insects. In this study, we identified and characterized five P450 genes from the transcriptome of Megalurothrips usitatus, a major pest of leguminous crops. Full-length cDNA sequences were cloned and subjected to comprehensive bioinformatic analyses. The encoded proteins exhibited typical hydrophobic properties, with secondary structures dominated by α-helices and random coils. Notably, phosphorylation site prediction revealed a high frequency of serine residues. Phylogenetic analysis demonstrated close evolutionary relationships between these P450s and their orthologs in Frankliniella occidentalis and Thrips palmi. Bioassays revealed that field-collected M. usitatus populations from Haikou had developed moderate resistance to both dinotefuran (LC50 = 844.248 mg/L) and sulfoxaflor (LC50 = 165.991 mg/L). Quantitative real-time PCR analysis showed that CYP6EB24 expression was dramatically upregulated by 8.9-fold (p < 0.0001) and 9.6-fold (p < 0.0001) following exposure to LC25 concentrations of dinotefuran and sulfoxaflor, respectively. Spatiotemporal expression profiling indicated highest CYP6EB24 transcript levels in female adults and thoracic tissues. Correspondingly, cytochrome P450 enzyme activity increased significantly (p < 0.05) after insecticide treatment at LC50 concentrations. These results provide robust experimental evidence that CYP6EB24 plays a pivotal role in the metabolic detoxification of dinotefuran and sulfoxaflor in M. usitatus. Our findings not only advance the understanding of P450-mediated resistance mechanisms in M. usitatus but also establish a foundation for future functional studies of detoxification genes in this economically important pest species.","PeriodicalId":8281,"journal":{"name":"Archives of Insect Biochemistry and Physiology","volume":"120 2","pages":"e70102"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Methoprene-Tolerant Orchestrates the Number of Larval Molts at the Second Instar Stage in an Herbivorous Ladybird 甲氧苯乙酯耐受性对草食性瓢虫二龄幼虫蜕皮数量的影响

IF 1.9 4区农林科学

Archives of Insect Biochemistry and Physiology Pub Date : 2025-09-30 DOI: 10.1002/arch.70099

Yi-Kuan Wu, Jia-Qing Yu, Lin Jin, Guo-Qing Li

{"title":"Methoprene-Tolerant Orchestrates the Number of Larval Molts at the Second Instar Stage in an Herbivorous Ladybird","authors":"Yi-Kuan Wu, Jia-Qing Yu, Lin Jin, Guo-Qing Li","doi":"10.1002/arch.70099","DOIUrl":"https://doi.org/10.1002/arch.70099","url":null,"abstract":"<div>\u0000 \u0000 Insect nymphal/larval instars vary widely across insect taxa and at the intraspecific level, they are orchestrated by two hormones, juvenile hormones (JH) and 20-hydroxyecdysone (20E). For insects whose nympha/larva molting events are more than 3, lack of JH signal causes premature metamorphosis and additional JH exposure induces supernumerary juvenile molts. In Drosophila melanogaster, the number of larval molts is fixed at two (dimolter) and is not affected by either JH or 20E signals. Larvae of a subset of Coleopterans are trimolters. Whether JH signal governs the number of larval molts in these Coleopteran trimolters deserves investigation. In the current study, we found that Methoprene-tolerant (Met) gene was actively transcribed from the first instar to pupal stages in an herbivorous ladybird Henosepilachna vigintioctomaculata. An injection of dsMet at the second, third and fourth (final) larval stages successfully knocked down the target gene, and disrupted the expression of both JH and 20E signaling genes. RNA interference for Met at the second instar larval stage reduced the number of larval molts from 3 to 2, and consequently caused premature metamorphosis and miniature pupae, as well as the impairment of larval-pupal transition. Contrarily, depletion of Met at the third and fourth instar larval periods arrested the larval development at the prepupal stage. Our findings suggest that JH signaling orchestrates the number of larval molts at the second instar stage in the H. vigintioctomaculata larvae.</div>","PeriodicalId":8281,"journal":{"name":"Archives of Insect Biochemistry and Physiology","volume":"120 2","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145197318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Functional Role of the PxGRHPR2 Gene in the Host Plant Adaptation of Diamondback Moth (Plutella xylostella) PxGRHPR2基因在小菜蛾寄主植物适应中的功能作用

IF 1.9 4区农林科学

Archives of Insect Biochemistry and Physiology Pub Date : 2025-09-25 DOI: 10.1002/arch.70100

Uroosa Zaheer, Faisal Munir, Qingxuan Qiao, Yussuf Mohamed Salum, Anam Noreen Abbas, Mubashir Tariq, Shihua Huang, Chanqin Zheng, Guang Yang, Weiyi He

{"title":"Functional Role of the PxGRHPR2 Gene in the Host Plant Adaptation of Diamondback Moth (Plutella xylostella)","authors":"Uroosa Zaheer, Faisal Munir, Qingxuan Qiao, Yussuf Mohamed Salum, Anam Noreen Abbas, Mubashir Tariq, Shihua Huang, Chanqin Zheng, Guang Yang, Weiyi He","doi":"10.1002/arch.70100","DOIUrl":"10.1002/arch.70100","url":null,"abstract":"<div>\u0000 \u0000 The diamondback moth (Plutella xylostella), a major lepidopteran pest with a wide host range, presents persistent challenges to sustainable agriculture due to its high adaptability to cruciferous host plants. Although glyoxylate/hydroxypyruvate reductases (GRHPRs) have been well-characterized in plants and humans, their functional role in insects, particularly in host plant adaptation, remains largely unexplored. In this study, we characterized PxGRHPR2, a member of the GRHPR gene family, using a bioinformatics analysis, expression profiling, and CRISPR/Cas9-mediated gene knockout. RT-qPCR analysis showed that PxGRHPR2 was predominantly expressed in larval stage, with the highest transcript levels observed in the second instar and larval midgut tissues. Three homozygous PxGRHPR2 knockout strains were successfully generated using CRISPR/Cas9 system. Mutation of PxGRHPR2 led to significant reductions in larval weight, survival, and eclosion rates when larvae were fed on radish seedlings, whereas no such effects were observed under artificial diet conditions. These findings suggest that PxGRHPR2 plays a critical role in detoxification and metabolic regulation, thereby facilitating host plant adaptability in P. xylostella. Overall, this study provides new insights into insect−plant interactions and identifies PxGRHPR2 as a potential molecular target for developing sustainable pest management strategies.</div>","PeriodicalId":8281,"journal":{"name":"Archives of Insect Biochemistry and Physiology","volume":"120 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145136286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Can the Supplementation Diet With Caryocar villosum (Aubl.) Pers Extracts Influence the Behavioral and Metabolic Parameters of Drosophila melanogaster? 在饲粮中添加核果绒毛（Aubl.）梨提取物对黑腹果蝇行为和代谢参数的影响？

IF 1.9 4区农林科学

Archives of Insect Biochemistry and Physiology Pub Date : 2025-09-25 DOI: 10.1002/arch.70101

Maria Eduarda Silva Soares, Andrielle Adelina Teodoro de Jesus, Douglas Lisboa Ramalho, Jonatha Flávio Souza Lemos, Diana França de Souza, Klenicy Kazumy de Lima Yamaguchi, Anderson Oliveira Souza

{"title":"Can the Supplementation Diet With Caryocar villosum (Aubl.) Pers Extracts Influence the Behavioral and Metabolic Parameters of Drosophila melanogaster?","authors":"Maria Eduarda Silva Soares, Andrielle Adelina Teodoro de Jesus, Douglas Lisboa Ramalho, Jonatha Flávio Souza Lemos, Diana França de Souza, Klenicy Kazumy de Lima Yamaguchi, Anderson Oliveira Souza","doi":"10.1002/arch.70101","DOIUrl":"https://doi.org/10.1002/arch.70101","url":null,"abstract":"Amazonian fruits, such as Caryocar villosum, are rich in phenolic compounds known to influence oxidative stress and mitochondrial function, suggesting a potential role in preventing age-related diseases. This study aimed to analyze the effect of a diet supplemented with C. villosum on behavioral and biochemical parameters in Drosophila melanogaster. D. melanogaster were fed a diet with C. villosum at different concentrations from the larval stage until the fifteenth day of adulthood. A diet supplemented with 0.075 mg/mL of C. villosum increased mortality (p < 0.01) and climbing ability (p < 0.0001) after 10 days of feeding. However, larvae fed with 0.005–0.0125 mg/mL of C. villosum showed no toxic effects. Biochemical analyses revealed that ingesting 0.01 mg/mL of C. villosum increased activities of acetylcholinesterase (p < 0.01) and citrate synthase (p < 0.001) in head tissues. Notably, lactate levels were also elevated (p < 0.01) in the heads of flies fed with 0.0125 mg/mL, suggesting metabolic modulation. These results suggest that C. villosum supplementation for 15 days enhances neural health in D. melanogaster, an alternative animal model for nutrition research, through the consumption of Amazonian fruit as C. villosum.","PeriodicalId":8281,"journal":{"name":"Archives of Insect Biochemistry and Physiology","volume":"120 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/arch.70101","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145146520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dynamic Regulation Mechanism of Calcium Ions on Muscle Fiber Contraction During Deformation Process of Honeybee Abdomen 钙离子对蜜蜂腹部变形过程中肌纤维收缩的动态调节机制

IF 1.9 4区农林科学

Archives of Insect Biochemistry and Physiology Pub Date : 2025-09-25 DOI: 10.1002/arch.70093

Yuling Zhang, Yifei Wang, Xu Pang, Jieliang Zhao, Yunqiang Yang, Shaoze Yan

{"title":"Dynamic Regulation Mechanism of Calcium Ions on Muscle Fiber Contraction During Deformation Process of Honeybee Abdomen","authors":"Yuling Zhang, Yifei Wang, Xu Pang, Jieliang Zhao, Yunqiang Yang, Shaoze Yan","doi":"10.1002/arch.70093","DOIUrl":"https://doi.org/10.1002/arch.70093","url":null,"abstract":"<div>\u0000 \u0000 Various physiological activities of the honeybee abdomen depend on muscle contraction, mainly regulated by calcium ions. Thus, the dynamic changes of calcium ions are crucial for unraveling the molecular mechanism of muscle contraction but remain unclear. Considering that calcium ions bind to troponin on thin filaments to induce the formation of actomyosin cross-bridges, fluorescence labeling technology can be employed to investigate the dynamic regulatory effect of calcium ions on muscle fibers. Here we show that the calcium ion concentration first increased and then gradually decayed under the simulation of L-glutamic acid, leading to a gradual decay of the changes in the length of muscle fibers until they were almost unchanged, at which point the maximum contraction was reached. The contraction rate of the muscle fibers was fastest at the beginning and then decreased as the calcium ion concentration decreased. The maximum extent of muscle fiber shortening sizes was about 20 μm, with the initial size of about 225 μm. A model of half sarcomere contraction stimulated by calcium ions was established to further verify the effects of calcium ions on muscle fiber contraction, and the consistent tendency with the experiment demonstrated good agreement on the regulatory effect of calcium ions on muscle fiber contraction. This finding provides a deeper understanding of the dynamic process of muscle contraction in insects and an important reference for the design of integrated soft-body actuators, especially ion-regulated actuators.</div>","PeriodicalId":8281,"journal":{"name":"Archives of Insect Biochemistry and Physiology","volume":"120 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145146519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bioactivity of Linalool Against Culex quinquefasciatus: Repellent and Larvicidal Evaluations 芳樟醇对致倦库蚊的生物活性：驱避和杀幼虫评价

IF 1.9 4区农林科学

Archives of Insect Biochemistry and Physiology Pub Date : 2025-09-22 DOI: 10.1002/arch.70098

Rajesh Kumar, Payal Mittal, Monika Airi

{"title":"Bioactivity of Linalool Against Culex quinquefasciatus: Repellent and Larvicidal Evaluations","authors":"Rajesh Kumar, Payal Mittal, Monika Airi","doi":"10.1002/arch.70098","DOIUrl":"https://doi.org/10.1002/arch.70098","url":null,"abstract":"<div>\u0000 \u0000 Mosquitoes spread a range of life-threatening illnesses such as malaria, dengue, zika virus, chikungunya, yellow fever, and many others, and cause up to 1 million deaths and 1 billion infections across the world every year. There has been growing interest in plant-based repellents that display bioactive compounds with insecticidal and repellent activities. In this review, the focus is on a natural monoterpene that has gained therapeutic properties, including antifungal, antibacterial, antioxidant, anticancer, and neuropharmacological activity, including anti-anxiety and sedative activity. The efficacy of linalool was assayed against mosquitoes in larvicidal and repellent bioassays. Larvicidal assays exhibited dose-dependent mortality: 82% at 1%, 87.4% at 2%, and 90.8% at 4% concentration after 24 h. Repellency cage assays exhibited good initial efficacy, with 1% linalool repelling 82.2% of mosquitoes, 2% repelling 81.8%, and 4% repelling 90.8%, very close to DEET's (N,N-diethyl-meta-toluamide) 93.4%. After 210 min, the 4% concentration had 82.2% repellency, while DEET had 89.6%. Tunnel tests revealed 4% linalool provided 90.2% repellency at 1 h and 84% at 3 h. The findings show that linalool, especially at high levels, is extremely effective as a repellent and larvicide. Its activity is as effective as that of DEET, the present synthetic repellent, and hence linalool can be utilized as an effective natural substitute for long-lasting mosquito control.</div>","PeriodicalId":8281,"journal":{"name":"Archives of Insect Biochemistry and Physiology","volume":"120 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0