Environmental Science: Nano最新文献

{"title":"Tailoring Nanomaterials towards Global One Health: A Promising Nano-strategy against Antibiotic Resistance","authors":"Feiran Chen, Shuhan Zhang, Xi Wang, Zhenyu Wang","doi":"10.1039/d4en00854e","DOIUrl":"https://doi.org/10.1039/d4en00854e","url":null,"abstract":"The management of antibiotic resistance gene (ARG) contamination in the soil-plant system is a critical area of research with significant implications for public health and environmental sustainability. Recently, engineered nanomaterials (ENMs) have been developed to enhance plant growth and address the global food crisis. Studies on the effects of nanomaterials mostly indicate an increase in the spread of antibiotic resistance, while emerging findings reveal the potential of ENMs in mitigating ARG pollution. Unlike existing mechanisms such as adsorption, DNA damage, and microbial disinfection involved in ARG removal, ENMs are specifically modified (e.g., with particular chemical compositions or surface charge adjustment) to inhibit the transfer of ARGs and migration of antibiotic-resistant bacteria. The integration of ENMs with advanced technologies (e.g., CRISPR gene editing) holds great promise for remediating antibiotic resistance in soil-plant systems. Here, we provide an overview of ENM-ARG interactions and propose applications of tailored ENMs to inhibit ARG dissemination during the development of nano-enabled agriculture, addressing major challenges and directions for optimizing efficacy and safety of ENMs-based strategies for mitigating ARG contamination in agriculture.","PeriodicalId":73,"journal":{"name":"Environmental Science: Nano","volume":"35 1","pages":""},"PeriodicalIF":8.131,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143031249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phenotypic profiling reveals polystyrene nanoplastics elicit sublethal and lethal effects on cellular morphology in rainbow trout gill epithelial cells","authors":"Lissett Guadalupe Diaz, Rebecca Klaper","doi":"10.1039/d4en01149j","DOIUrl":"https://doi.org/10.1039/d4en01149j","url":null,"abstract":"Extensive knowledge is available on the impacts of both engineered nanomaterials (ENMs) and microplastics, yet there remains a critical gap in understanding the impacts of nanoplastics at the cellular and subcellular effects at sublethal concentrations. This study investigates the impacts of PS NPs on Oncorhynchus mykiss (rainbow trout) gill epithelial cells, emphasizing the crucial role of surface charge in nano-bio interactions. The current study employs both traditional and non-traditional toxicological techniques presenting an image-based study to examine PS NP-cellular interactions at sublethal doses. Our findings demonstrated that relative to the uncharged and negatively charged PS NPs, the positively charged PS NPs significantly decreased cell viability at 4 μg mL<small>^-1</small> (EC50: 4.31 μg mL<small>^-1</small>). However, at the sublethal concentration of 2 μg mL<small>^-1,</small> phenotypic profiling analysis indicates that positively charged PS NPs elicit a significant change to cellular morphology and suggests key interactions with subcellular components. As the impacts measured are novel, further research into the underlying mechanisms will contribute to our understanding of nanoparticle toxicity in vertebrate species guiding both the policy and sustainable design of nanoparticles.","PeriodicalId":73,"journal":{"name":"Environmental Science: Nano","volume":"113 1","pages":""},"PeriodicalIF":8.131,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143031250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Facet-dependent growth and dissolution of hematite resulting from autocatalytic interactions with Fe(II) and oxalic acid","authors":"Sandra Taylor, John Cliff, Thomas W Wiestma, Kevin Rosso","doi":"10.1039/d4en01004c","DOIUrl":"https://doi.org/10.1039/d4en01004c","url":null,"abstract":"The ability to simultaneously monitor the flux of iron atoms within the solution and solid phases can provide considerable insight into mechanisms of iron oxide mineral transformations. The autocatalytic interaction between hematite and Fe(II)-oxalate has long been of interest for its environmental and industrial relevance. In this study we take advantage of iron isotopic labelling and mass-sensitive imaging at the single particle scale to determine how changes in solution composition correlate with the morphologic evolution of faceted, micrometer-sized hematite platelets. Net dissolution is confirmed through analyses of aqueous iron chemistry, as well as by quantitative atomic force microscopy. Isotopic mapping techniques show that Fe(II) readily adsorbs to (001) and (012) surfaces in the absence of oxalate, but when oxalate is present selective dissolution of the (001) surface prevails and 57Fe deposition via recrystallization is not observed. Comparison between particle microtopographies following reaction with Fe(II), oxalate, and Fe(II)-oxalate show substantially different behavior, consistent with distinct mechanisms of interaction with hematite surfaces. The extensive characterization conducted on the coupled solution/solid dynamics in this system provides new insight for distinguishing crystal growth, dissolution, and recrystallization processes.","PeriodicalId":73,"journal":{"name":"Environmental Science: Nano","volume":"18 1","pages":""},"PeriodicalIF":8.131,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143026770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection and quantification of nanoparticles in runoff from a highly trafficked urban motorway","authors":"Malak DIA, Pierre-Emmanuel Peyneau, Denis Courtier-Murias, Béatrice Béchet","doi":"10.1039/d4en00552j","DOIUrl":"https://doi.org/10.1039/d4en00552j","url":null,"abstract":"Urban rainfall and runoff are major transport vectors for pollutants into the aquatic environment. In this context, road traffic is a significant factor in the contamination of the urban environment in general, and runoff in particular. Some metals, such as Cu, Zn, Fe, and Ti, have been found in dissolved fraction (&lt; 0.45 μm) in such water. The present study focuses on characterizing the number concentration and mass distribution of nanoparticles (NPs) containing Ti, Fe, Zn, and Cu in runoff from a heavily trafficked urban motorway (≈ 100,000 vehicles/day) in Nantes, western France. Seven runoff samples were taken between July 2023 and March 2024. A rainfall sample was also taken in the same proximity for comparative purposes, providing knowledge of atmospheric wet deposition levels. Using two sample preparation methods, filtration, and ultra-filtration, single particle ICP-MS (sp-ICP-MS) analysis confirmed the existence of the targeted elements in nanoparticulate fraction. Ti was found to be the most abundant element, followed by Fe, while Zn and Cu were less prevalent, with average number concentrations of 4.83 x 10^8, 1.68 x 10^8, 7.78 x 10^7 and 9.04 x 10^7 particles/L, respectively. Except for Fe, runoff samples exhibited higher concentrations of Ti, Zn, and Cu nanoparticles compared to the rainfall sample, with a larger average equivalent diameter indicating a likely anthropogenic origin. Comparisons between sample preparation methods demonstrates that the effectiveness of ultrafiltration is element dependent.","PeriodicalId":73,"journal":{"name":"Environmental Science: Nano","volume":"45 1","pages":""},"PeriodicalIF":8.131,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143020407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a Novel MOFs-Based Nanofiber for Highly Selective Removal of Cobalt from Aqueous Solutions","authors":"Yinyin Peng, Yang Luo, Shuyuan Liu, Cong Yin, Derong Liu, Bowen Hu, Xiaoqin Pu, Guoyuan Yuan, Wei Xiong","doi":"10.1039/d4en01058b","DOIUrl":"https://doi.org/10.1039/d4en01058b","url":null,"abstract":"The challenge of cobalt ion separation was addressed by developing a novel MOFs nanofiber, Co(II)-PIIMs. Initially, Co(II)-SIM-IIP were synthesized using zinc-based MOFs (SIM-1) as a matrix and tetraethylpentadiamine (TEPA) as a functional monomer through ion imprinting technique (IIT). Subsequently, Co(II)-PIIMs-x nanofibers were fabricated via electrospinning. Co(II)-SIM-IIP were incorporated as fillers, while PAN was used as the substrate, aiming at selectively separating cobalt ions. Optimal performance was achieved with a 10% doping level of Co(II)-SIM-IIP, resulting in adsorptive capacity peaking at 112.74 mg/g, along with membrane flux of 1095 L/m² h, and a retention rate of 43.49%. The material exhibited excellent selectivity with high selectivity factors for various ions such as Ca2+ (7.42), K+ (55.98), Mg2+ (72.30), and Ni2+ (1.28). Adsorption mechanism results indicated that cobalt adsorption by Co(II)-PIIMs is governed by the adsorption rate control step and the even distribution of cobalt on the surface, aligning with chemisorption properties. After five adsorption-desorption cycles, Co(II)-PIIMs demonstrated excellent regeneration capability, maintaining over 95% of their initial adsorption capacity. These impressive selectivity factors underscore the material's capability to selectively adsorb cobalt ions over other competing ions, making it a promising candidate for efficient separation and purification processes in environmental remediation applications.","PeriodicalId":73,"journal":{"name":"Environmental Science: Nano","volume":"11 1","pages":""},"PeriodicalIF":8.131,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142992327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physiological and transcriptomic responses of Chlorella vulgaris to novel antibacterial nanoparticles of ethyl cyanoacrylate polymer","authors":"Di Zhang, Keqing Liu, Chengcheng Feng, Xianmin Wang, Ayat J. S. Al-Azab, Han Lu, Haiyan Ma, Ying Tang, Li Xu, Takeshi Ohama, Fantao Kong","doi":"10.1039/d4en00861h","DOIUrl":"https://doi.org/10.1039/d4en00861h","url":null,"abstract":"The ethyl cyanoacrylate nanoparticles (ECA-NPs) have recently been reported as promising novel antibacterial NPs capable of inhibiting the growth of several Gram-positive and Gram-negative bacteria. However, the effects of ECA-NPs on microalgae, which are primary producers in aquatic ecosystems, remain unknown. In this study, we examined the effects of ECA-NPs on the microalga Chlorella vulgaris (Chlorella) at both cellular and molecular levels. A high concentration of ECA-NPs (100 μg/mL) exhibited strong growth inhibitory effects on Chlorella. In the ECA-NPs-treated cells, transmission electron microscope (TEM) observations showed the prominent internalization of ECA-NPs in the periplasmic space and vacuoles. Moreover, notable morphological changes such as a thinner cell wall, stacked thylakoid structure, and plasmolysis were observed. ECA-NPs exposed Chlorella secreted more extracellular polymeric substances (EPS) and accumulated more storage lipids (mainly triacylglycerol, TAG) compared to the control. However, the contents of total fatty acids and starch were decreased, and photosynthetic activity was reduced. In addition, the content of intracellular reactive oxygen species (ROS) and the activities of antioxidant enzymes in ECA-NPs-treated cells were significantly higher than in the control. Transcriptomic analysis revealed the downregulation of genes that are involved in drug binding/catabolic process, chemical stimulus detection, and cell wall component catabolic process (chitin catabolism), while genes involved in photosynthetic membrane and plastid thylakoid were upregulated. These results indicated that the effects of ECA-NPs exposure are not limited to specific metabolic pathways, but rather influence metabolic pathways across the entire cell. This study also provided new insights into the potential toxic effects associated with cyanoacrylate NPs in phytoplankton.","PeriodicalId":73,"journal":{"name":"Environmental Science: Nano","volume":"24 1","pages":""},"PeriodicalIF":8.131,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142992329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biologically synthesized Fe0-based nanoparticles and their application trends as catalysts in the treatment of chlorinated organic compounds: a review","authors":"Son Hong Nguyen, Ngoc Toan Vu, Hoang Van Nguyen, Binh Nguyen, Trung Thien Luong","doi":"10.1039/d4en00843j","DOIUrl":"https://doi.org/10.1039/d4en00843j","url":null,"abstract":"This review explores the advancements and trends in biologically synthesized Fe⁰-based nanoparticles (NPs) and their applications as catalysts in treating chlorinated organic compounds. The persistent nature and bioaccumulative characteristics of chlorinated organic compounds enable their accumulation in water, soil, and the food chain, leading to significant environmental and human health issues. The widespread presence of these toxic substances underscores the urgent need for effective treatment and remediation strategies. Biologically synthesized Fe⁰-based NPs are recognized for their considerable surface area, potent reduction properties, and environmental compatibility. These attributes render them a promising approach for the remediation of chlorinated compounds. This review categorizes synthesis methods into key groups: microorganisms, plant extracts, biological waste, and industrial-agricultural by-products. Recent studies highlight the promising applications of bio-NPs in environmental remediation, emphasizing their potential for sustainable and efficient treatment solutions. This analysis thoroughly examines current trends in the application and enhancement of nanoparticle activity, delineating various challenges and future prospects comprehensively. It offers well-defined research directions with high practical relevance, aiming to contribute to advancing knowledge and guiding future research endeavors in the field.","PeriodicalId":73,"journal":{"name":"Environmental Science: Nano","volume":"57 1","pages":""},"PeriodicalIF":8.131,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142990723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expansion Microscopy Revealed Specific Impacts of Nano Zinc Oxide on Early Organ Development in Fish","authors":"Mengyu WANG, Wen-Xiong Wang","doi":"10.1039/d4en01071j","DOIUrl":"https://doi.org/10.1039/d4en01071j","url":null,"abstract":"Nanomaterials exhibit significant advantages in biomedical applications. However, their potential risks to organisms cannot be overlooked, particularly during early development. Traditional methods for assessing organ-specific toxicity are limited by their difficulty in exploring differences between materials at the nanoscale resolution. The novel expansion microscopy technique (ExM) provides an effective solution for high-resolution nanoscale imaging, allowing biological samples to be expanded approximately 4.5 times in three-dimensional space. ExM enables the visualization of proteins and nucleic acid targets in cells and tissues using conventional optical microscopy, achieving nanoscale imaging. The widespread application of nano zinc oxide (nZnO) in the biomedical field has raised concerns regarding toxicity. This study systematically assesses the toxicological changes and sources of nZnO and Zn²⁺ in the visual, skeletal muscle, and digestive systems. Our results indicated that appropriate concentrations of nZnO supported the normal early development in the visual and skeletal muscle systems, while potentially leading to excessive toxicity in the digestive system. Conversely, the concentrations of nZnO suitable for the development of the digestive system may be inadequate for the needs of the visual and skeletal muscle systems. This discrepancy may arise from differences in the solubility and bioaccessibility of nZnO in gastrointestinal fluids. Further RNA sequencing revealed differences in the sensitivity of various organs to nanomaterial exposure, highlighting the necessity of implementing comprehensive risk assessment strategies in toxicology. Overall, we visualized and quantified the subtle developmental toxicities of nZnO and Zn²⁺ across different organs for the first time. The application of expansion microscopy technique offered a novel perspective for evaluating the toxicity of nanomaterials.","PeriodicalId":73,"journal":{"name":"Environmental Science: Nano","volume":"79 1","pages":""},"PeriodicalIF":8.131,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142990726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Designing Safer Nanohybrids: Stability and Ecotoxicological Assessment of Graphene Oxide-Gold Nanoparticles Hybrids in Embryonic Zebrafish","authors":"Bashiru Ibrahim, Taiwo Hassan Akere, Pankti Dhumal, Eugenia Valsami-Jones, Swaroop Chakraborty","doi":"10.1039/d4en01173b","DOIUrl":"https://doi.org/10.1039/d4en01173b","url":null,"abstract":"Graphene oxide (GO) and graphene oxide-gold (GO-Au) nanohybrids offer promising applications in nanomedicine, biosensing, and environmental technology due to their unique properties. However, concerns regarding their environmental and biological safety remain largely unexplored. This study, using a Safe and Sustainable by Design (SSbD) approach, evaluates the cytotoxicity, oxidative stress, and dispersion stability of GO and GO-Au nanohybrids in zebrafish ZF4 cells. GO was synthesised using a modified Hummer’s method and GO-Au nanohybrids were prepared by incorporating gold nanoparticles (AuNPs) into the GO matrix. Physicochemical characterisation revealed enhanced dispersion stability of GO-Au nanohybrids, retaining over 98% of their initial absorbance in ultrapure water (UPW) and over 95% in DMEM/F12 after 48 hours. In contrast, GO displayed higher levels of sedimentation. Toxicity assessments indicated a dose- and time-dependent decrease in cell viability. After 72 hours, ZF4 cell viability was reduced to 39.5% at 150 µg/mL of GO, whereas GO-Au treatment at the same concentration exhibited a less severe reduction (54.5% viability). Reactive oxygen species (ROS) generation was significantly higher in GO-treated cells compared to GO-Au, with GO generating approximately 2x more ROS at concentrations of 50 µg/mL and 100 µg/mL. Apoptosis and necrosis rates were also significantly elevated in GO-treated cells, with necrosis reaching 53.1% at 100 µg/mL, compared to 14.6% in GO-Au-treated cells. The findings demonstrate that the incorporation of AuNPs reduce cytotoxicity and oxidative stress by enhancing the colloidal stability of GO-Au nanohybrids. This study provides critical baseline data on the interaction of GO-based nanomaterials (NMs) with biological systems and highlights the importance of NMs modification for safer, more sustainable applications.","PeriodicalId":73,"journal":{"name":"Environmental Science: Nano","volume":"33 1","pages":""},"PeriodicalIF":8.131,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142992328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coating of complex metallic surfaces with passivated silver nanoparticles for long-term biofilm control","authors":"Ali Ansari, Afsana Munni, Dianne Carrillo, Matthew Pedersen, Rafiqul Islam, Francois Perreault","doi":"10.1039/d4en00797b","DOIUrl":"https://doi.org/10.1039/d4en00797b","url":null,"abstract":"Deep space missions will bring new challenges, beyond our experience so far with International Space Station, to life support systems including water supply. The complexity of these missions might leave spacecrafts and facilities uncrewed for several months. In this situation, biofilm growth can deteriorate the quality of stored water and cause water supply system failure during reinitiation, threating the mission success. Antimicrobial coatings have been used for biofilm mitigation in various conditions. A successful coating to control biofilm formation in deep space mission, among other things, must have long lifetime considering the duration of such missions. In this study, a solution was provided to the biggest drawback of silver nanoparticles as antimicrobial coating; short lifetime. Passivating with sulfide was tested to control silver ion release from silver nanoparticles, hence, prolonging antimicrobial activity. Stainless steel bellow pieces, as the most prone parts to biofilm growth, was chosen as the substrate. The pieces were coated with silver and passivated silver with different passivation degree to find the optimum condition. The substrates were exposed to Pseudomonas aeruginosa in M9 medium for 12 months for biofilm formation. The bacteria count on the bellow pieces as a representative of biofilm as well as bacteria count and silver ion concentration in M9 medium were measured at 1.5, 3, 6, and 12-month timepoints. Passivation slowed down silver ion release rate from silver nanoparticles, however, biofilm mitigation at the end of the experiment for one passivated coating was the same as silver coating, which means the passivated coating can last longer by releasing less antimicrobial agent, silver ions. Besides performance in biofilm mitigation, we demonstrated that the bellows can be coated homogeneously in a continuous reactor and passivation can enhance the stability of the coating to mechanical stress during expansion/retraction of the bellow, paving the way for application of passivated silver coating for space missions.","PeriodicalId":73,"journal":{"name":"Environmental Science: Nano","volume":"102 1","pages":""},"PeriodicalIF":8.131,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142991015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}