{"title":"Integration of NiTiO3 Films onto TiO2 Nanorods as Photoanodes for Glucose Detection with Near-Infrared Light","authors":"Yahan Wu, Jiaqi Zhang, Shun Zhao, Yueping Li, Pingru Cai, Dandan Zheng*, Guoen Cai* and Yuanxing Fang*, ","doi":"10.1021/acsanm.4c0366010.1021/acsanm.4c03660","DOIUrl":"https://doi.org/10.1021/acsanm.4c03660https://doi.org/10.1021/acsanm.4c03660","url":null,"abstract":"<p >Diabetes remains a significant chronic disease, with its prevalence projected to exceed 700 million by 2045. Monitoring glucose levels through conventional methods is crucial for mitigating the associated health risks. In this study, NiTiO<sub>3</sub> films are loaded on TiO<sub>2</sub> nanorods to create photoanodes, which are applied for glucose detection using near-infrared (NIR) light illumination. This approach achieved a detection limit of 0.01 mM with selectivity reaching up to 95%. Additionally, the long-term stability was confirmed for at least 16 weeks. This study demonstrates the potential of using NiTiO<sub>3</sub>-based nanomaterials as an NIR-driven sensor for glucose detection.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":null,"pages":null},"PeriodicalIF":5.3,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142407541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Role of Iodide in the Formation of Gold Nanotriangles","authors":"Jun Zhu, and , R. Bruce Lennox*, ","doi":"10.1021/acsanm.4c0511810.1021/acsanm.4c05118","DOIUrl":"https://doi.org/10.1021/acsanm.4c05118https://doi.org/10.1021/acsanm.4c05118","url":null,"abstract":"<p >Gold nanotriangles, one of a family of nanoprisms, have attracted a great deal of interest due to their promising applications in catalysis, electronics, imaging, diagnostics, and photothermal therapy. The crucial role of iodide in the formation of anisotropic gold nanotriangle (AuNT) has been assigned to the inhibition of Au(111) facet growth and as a digestion agent (as I<sub>3</sub><sup>–</sup>) of non-nanotriangle impurities. However, neither I<sup>–</sup> nor I<sup>3–</sup> are detectable in the reaction conditions of the growth solution. Instead, an Au(I) complex, [AuI<sub><i>y</i></sub>Cl<sub>2–<i>y</i></sub>]<sup>-</sup>, has been identified for the first time as a synthetic precursor of Au nanotriangles. This complex forms in solution on mixing AuCl<sub>4</sub><sup>–</sup>, I<sup>–</sup>, and ascorbic acid. [AuI<sub><i>y</i></sub>Cl<sub>2–<i>y</i></sub>] is readily reduced by ascorbic acid to form <i>in situ</i> AuNP seeds. Preferential adsorption of <i>in situ</i> generated I<sup>–</sup> on the Au(111) facets of the Au(0)NP seeds, relative to the Au(100) edges of a developing plate, results in the selective growth of the latter compared to the former. Control of the formation and reaction conditions of this precursor complex provides an entry point to the sought-after reproducible, one-pot synthesis of AuNT. This refinement of the role of iodide introduces approaches to control the outcomes of the metal nanoparticle synthesis.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":null,"pages":null},"PeriodicalIF":5.3,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142407549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Binghui Zhou, Xinlei Ding, Yun Chen, Hanyang Wang, Yadong Liu, Chengfei Wang, Guangmei Bai and Wenge Qiu*,
{"title":"Carbon Defects on N-Doped Carbon Promote Catalytic Activity of Pd Nanoparticles for the Selective Hydrogenation of Quinoline","authors":"Binghui Zhou, Xinlei Ding, Yun Chen, Hanyang Wang, Yadong Liu, Chengfei Wang, Guangmei Bai and Wenge Qiu*, ","doi":"10.1021/acsanm.4c0410010.1021/acsanm.4c04100","DOIUrl":"https://doi.org/10.1021/acsanm.4c04100https://doi.org/10.1021/acsanm.4c04100","url":null,"abstract":"<p >The activation process is a key step in preparing porous carbon. Herein, three kinds of green activators were separately used to successfully prepare N-doped porous carbons through a two-step strategy: hydrothermal carbonization and chemical activation using microcrystalline cellulose as the carbon source and urea as the nitrogen source. Palladium was deposited on these N-doped microcrystalline cellulose-based carbons (NMC-X, where X represents the activator) via a traditional deposition–precipitation method, and the resulting Pd nanoparticle catalysts (Pd/NMC-X) showed high activity in the selective hydrogenation of quinoline under mild conditions, particularly Pd/NMC-ZC (ZC, zinc carbonate), which achieved complete conversion of quinoline within 100 min at 40 °C and 4 atm H<sub>2</sub>. Characterization results suggest that the high activity of Pd/NMC-ZC is mainly attributed to the special electronic structure of its Pd species, particularly the distribution of valence states and reducibility of Pd and the high hydrogen spillover capacity between Pd and NMC-ZC. The chemical activation by ZC leads to the formation of multiple defect sites on the carbon skeleton, modifying the carbon surface properties to enhance hydrogen spillover. This also provides an excellent environment for Pd nanoparticle anchoring, thus increasing the Pd-support interactions and regulating the electronic structure of Pd.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":null,"pages":null},"PeriodicalIF":5.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142407724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bruno Zappone*, Marco Giuseppe Geloso, Tiziana Ritacco, Maria Penelope De Santo, Atilla Eren Mamuk and Michele Giocondo,
{"title":"Surface Alignment of Liquid Crystal Films on Nanometer-Thick 3D-Printed Line Patterns with Arbitrary Topologies: Implications for Polarization Gratings, Q-Plates, and Beam Steerers","authors":"Bruno Zappone*, Marco Giuseppe Geloso, Tiziana Ritacco, Maria Penelope De Santo, Atilla Eren Mamuk and Michele Giocondo, ","doi":"10.1021/acsanm.4c0219710.1021/acsanm.4c02197","DOIUrl":"https://doi.org/10.1021/acsanm.4c02197https://doi.org/10.1021/acsanm.4c02197","url":null,"abstract":"<p >Liquid crystal films play a key role in advancing next-generation optical and photonic devices that require a precise in-plane modulation of optical anisotropy. This study employs multiphoton direct laser writing, a high-resolution three-dimensional (3D) printing method, to fabricate pseudoperiodic patterns of lines and grooves on glass surfaces for the in-plane alignment of liquid crystal films. Single layers of lines with submicron thickness and line spacing were fabricated in less than half an hour and forced the in-plane alignment of a liquid crystal film with a thickness of about 10 μm. We validate the method on patterns with singular topologies designed to induce the nucleation of disclination defects with a predetermined spatial arrangement, orientation, and topological strength. Compared to other surface patterning methods, high-resolution 3D printing provides the unique advantage of direct surface fabrication, enabling the creation of nonflat geometries such as terraces and lenses and expanding the design and functionalities of liquid crystal devices. We anticipate that this method will be used to create thin-film devices such as polarization gratings, beam steerers, and q-plates for manipulating polarized and structured light.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":null,"pages":null},"PeriodicalIF":5.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142407725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Metronomic Mild-Temperature Photothermal Therapy Modulating Tumor-Associated Macrophage Repolarization as a Neoadjuvant Immunotherapy","authors":"Hanye Yao, Yixin Xing, Yuying Yin, Jingqiang Xue, Chenlu Yin and Wei Gu*, ","doi":"10.1021/acsanm.4c0439710.1021/acsanm.4c04397","DOIUrl":"https://doi.org/10.1021/acsanm.4c04397https://doi.org/10.1021/acsanm.4c04397","url":null,"abstract":"<p >Neoadjuvant immunotherapy is superior to adjuvant immunotherapy in terms of immune suppression relief and antitumor immunity activation but inevitably suffers from immune-related toxicities. To minimize the toxic side effects, a local metronomic mild-temperature photothermal therapy (PTT) is proposed herein as a neoadjuvant immunotherapy. It was disclosed that the Prussian blue nanoparticle (PBNP)-mediated metronomic mild-temperature PTT effectively inhibited the growth of both primary and distal tumors on 4T1 xenograft tumor-bearing mice by effectively reversing the immunoimpressive TME through repolarizing M2-like TAMs to tumoricidal M1-like ones. Synergistically, the reprogrammed M1-like phenotype upregulated the percentage of cytotoxic T lymphocytes in the spleen and tumor, leading to an activated systemic immunity. This together with the demonstrated biosafety underscores the great potential of PBNP-mediated metronomic mild-temperature PTT as immunotherapy for reducing tumor burden presurgery and preventing tumor reoccurrence and metastasis postsurgery with minimized side toxic effects.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":null,"pages":null},"PeriodicalIF":5.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142407720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hui-Juan Zhang*, Bo Chen, Xiaoxiong Feng, Miaomiao Yu, Jiangyu Luo and Yuhua Xue*,
{"title":"Nanoparticles of CoFeZn Supported on N-Doped Carbon as Bifunctional Catalysts for Oxygen Reduction and Oxygen Evolution","authors":"Hui-Juan Zhang*, Bo Chen, Xiaoxiong Feng, Miaomiao Yu, Jiangyu Luo and Yuhua Xue*, ","doi":"10.1021/acsanm.4c0429110.1021/acsanm.4c04291","DOIUrl":"https://doi.org/10.1021/acsanm.4c04291https://doi.org/10.1021/acsanm.4c04291","url":null,"abstract":"<p >Oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) are two important reactions in clean energy conversion devices. It is necessary to develop nonprecious metal-based bifunctional catalysts for ORR and OER. In this work, a multimetal bifunctional catalyst, nanoparticles of trimetallic CoFeZn supported on N-doped carbon (CoFeZn/NC), is prepared by one-step carbonizing the mixture of M-ZIFs (M = Fe, Co, and Zn), carbon black, and melamine. CoFeZn/NC has a more mesoporous structure and a higher specific surface area of 1029.6 m<sup>2</sup>/g compared to FeCo/NC, which is attributed to the easy volatilization of Zn at high temperatures. It also has high contents of pyridinic N (35.8%) and pyrrolic N (31.1%), abundant metal active sites, and exhibits strong synergistic effects between these nanoparticles of metals. Better than the single-metal catalysts (Co/NC, Fe/NC, and Zn/NC) and bimetallic catalysts (CoFe/NC, FeZn/NC, and CoZn/NC), CoFeZn/NC has an ORR peak potential of 0.90 V (vs. RHE) and a half-wave potential of 0.87 V (vs. RHE) in 0.1 M KOH solution, and exhibits excellent stability and methanol resistance. For OER, CoFeZn/NC has the lowest overpotential of 319.9 mV at a current density of 10 mA/cm<sup>2</sup> and a Tafel slope of 82.47 mV dec<sup>–1</sup>.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":null,"pages":null},"PeriodicalIF":5.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142407618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Junwon Jang, Seongmin Kim, Suyong Park, Soomin Kim, Sungjun Kim* and Seongjae Cho*,
{"title":"Leaky 2T Dynamic Random-Access Memory Devices Based on Nanometer-Thick Indium–Gallium−Zinc-Oxide Films for Reservoir Computing","authors":"Junwon Jang, Seongmin Kim, Suyong Park, Soomin Kim, Sungjun Kim* and Seongjae Cho*, ","doi":"10.1021/acsanm.4c0450110.1021/acsanm.4c04501","DOIUrl":"https://doi.org/10.1021/acsanm.4c04501https://doi.org/10.1021/acsanm.4c04501","url":null,"abstract":"<p >This paper explores the integration of indium–gallium–zinc oxide (IGZO)-based 2-transistor 0-capacitor dynamic random-access memory (2T0C DRAM, or shortly, 2T DRAM) into reservoir computing for advanced semiconductor artificial intelligence (AI) applications. The short-term memory characteristics of IGZO 2T DRAM enable rapid read–write speeds essential for processing time-varying input data. Experimental results confirm high on/off ratios and leaky retention behaviors. The study also examines paired-pulse facilitation (PPF) phenomena, offering insights into reinforcement mechanisms for cognitive computing. Finally, the reservoir computing approach achieves notable pattern recognition accuracy with a 4-bit pulse scheme, showcasing its effectiveness in complex data sets.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":null,"pages":null},"PeriodicalIF":5.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142407719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gold Nanocluster-Based Capture-Detection Platform for Clinical Diagnosis of Early Lung Cancer","authors":"Liping Dai, Zhi Wang, Fengqi Chen, Jiaqi Li, Hanke Ma, Wenke Sun, Songyun Ouyang and Xiuxia Wang*, ","doi":"10.1021/acsanm.4c0438110.1021/acsanm.4c04381","DOIUrl":"https://doi.org/10.1021/acsanm.4c04381https://doi.org/10.1021/acsanm.4c04381","url":null,"abstract":"<p >The detection of autoantibodies (AAbs) with low-cost and noninvasiveness advantages has emerged as a promising technique for the diagnosis of early-stage lung cancer (LC). However, the specificity and sensitivity are frequently restricted to the characteristics of the antigens and the detection systems such as an enzyme-linked immunosorbent assay. Here, a highly sensitive and specific gold nanocluster-based capture-detection platform was developed to detect anti-PDL1 AAb as the biomarker of LC, for the diagnosis of early-stage LC. The nano capture-detection platform was composed of streptavidin magnetic beads conjugated PDL1 peptide (MB-peptide), serving as the capture probe, and goat-anti-human-IgG conjugated horseradish peroxidase-coated gold nanoclusters (anti-IgG-HRP-AuNCs) as the detection nanoprobe. Notably, the nanoplatform exhibited strikingly sensitive and specific detection of anti-PDL1 AAb, owing to the integration of the MB-peptide’s precision recognition capabilities with the excellent peroxidase activity and profound affinity for IgG displayed by the anti-IgG-HRP-AuNCs. Furthermore, the innovative nanoplatform harnessing optical detection technology significantly boosted detection efficiency and dramatically reduced the analysis time from the traditional 12 h process to a mere 50 min. Additionally, this advanced system demonstrated significantly enhanced sensitivity and specificity in diagnosing early-stage LC, substantiating the tremendous potential of the AuNCs-based capture-detection platform for clinical applications in the early detection of LC in the future.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":null,"pages":null},"PeriodicalIF":5.3,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142408217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fabrication of Color-Tunable Gold Nanoclusters and Their Application for Information Encryption","authors":"Fengjie Zhou, Jing Fu, Mengqi Yang, Jinglin Shen* and Wei Qi*, ","doi":"10.1021/acsanm.4c0503410.1021/acsanm.4c05034","DOIUrl":"https://doi.org/10.1021/acsanm.4c05034https://doi.org/10.1021/acsanm.4c05034","url":null,"abstract":"<p >The unique luminescence properties of gold nanoclusters (AuNCs) have attracted intense research interest in multiple areas. However, most AuNCs exhibit only a single-color emission. Achieving color-tunable emission through single AuNCs is attractive but still challenging. Herein, a switchable fluorescence strategy was introduced by integrating an aggregation-caused quenching (ACQ)-type ligand into an aggregation-induced emission (AIE)-type nanocluster system. In the AIE/ACQ strategy, 4,6-diamino-2-pyrimidinethiol (DPT)-AuNCs with color-tunable emission were developed: in the dimethylformamide (DMF)/water system, the DPT-AuNCs were dissociated and blue fluorescence was obtained, whereas in the MeOH/water system, DPT-AuNCs aggregated and strong orange phosphorescence was obtained. The emission color from orange to blue could also be switched by adjusting the solvent composition. Based on this strategy, the color-tunable AuNCs system was further employed for dynamic information encryption.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":null,"pages":null},"PeriodicalIF":5.3,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142408348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kana Kondo, Mojtaba Karimi Habil*, Kojiro Senda, Masato Adachi, Kenta Morita, Tatsuo Maruyama, Hiroshi Sugimoto* and Minoru Fujii,
{"title":"Size- and Wavelength-Selective Optical Heating in Mie-Resonant Silicon Nanospheres for Nanothermometry and Photothermal Applications","authors":"Kana Kondo, Mojtaba Karimi Habil*, Kojiro Senda, Masato Adachi, Kenta Morita, Tatsuo Maruyama, Hiroshi Sugimoto* and Minoru Fujii, ","doi":"10.1021/acsanm.4c0438910.1021/acsanm.4c04389","DOIUrl":"https://doi.org/10.1021/acsanm.4c04389https://doi.org/10.1021/acsanm.4c04389","url":null,"abstract":"<p >The photothermal heating properties of perfectly spherical crystalline silicon nanoparticles having Mie resonances in the visible range are studied under different illumination wavelengths by using the Raman scattering peak as a nanothermometer. Analytical calculations reveal that the magnetic quadrupole (MQ) Mie mode is the most suitable mode for photothermal heating. The experimentally obtained size and illumination wavelength dependence of the temperature rise agrees quantitatively with numerical simulations, and the heating efficiency reaches up to 381 K/(mW/μm<sup>2</sup>) when the illumination wavelength of 633 nm matches the MQ resonance. Conversely, tuning the illumination wavelength to a relatively nonabsorbing mode, such as the electric dipole (ED) mode, can significantly reduce the heating effect. In this context, the ED mode functions as a practically heating-less nanoantenna, promoting the surface-enhanced fluorescence of nearby dye molecules, while high-<i>Q</i> modes, e.g., MQ and electric quadrupole (EQ) modes, serve as an optical heating platform. Furthermore, the photothermal heating and Raman thermometry of silicon nanoparticles in water and in cancer cells are demonstrated.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":null,"pages":null},"PeriodicalIF":5.3,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142408214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}