ACS Applied Nano Materials最新文献

{"title":"Correction to “Praziquantel Nanoparticle Formulation for the Treatment of Schistosomiasis”","authors":"Ana C. Mengarda, Bruno Iles, Vinícius C. Rodrigues, Ana L. L. do Nascimento, Victoria P. Machado, Walberson S. Reatgui, Patrícia S. Bento, Marina A. Radichi, Taís C. Silva, Fernanda S. Teixeira, Maria C. Salvadori, Marina M. Simões, Karen L. R. Paiva, Cesar K. Grisolia, Maria L. Fascinelli, Sebastião W. Silva, Marcílio S. S. Cunha-Filho, Sônia N. Bao, João P. F. Longo* and Josué de Moraes*, ","doi":"10.1021/acsanm.5c0247610.1021/acsanm.5c02476","DOIUrl":"https://doi.org/10.1021/acsanm.5c02476https://doi.org/10.1021/acsanm.5c02476","url":null,"abstract":"","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 22","pages":"11730 11730"},"PeriodicalIF":5.3,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsanm.5c02476","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144220508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to \"Praziquantel Nanoparticle Formulation for the Treatment of Schistosomiasis\".","authors":"Ana C Mengarda, Bruno Iles, Vinícius C Rodrigues, Ana L L do Nascimento, Victoria P Machado, Walberson S Reatgui, Patrícia S Bento, Marina A Radichi, Taís C Silva, Fernanda S Teixeira, Maria C Salvadori, Marina M Simões, Karen L R Paiva, Cesar K Grisolia, Maria L Fascinelli, Sebastião W Silva, Marcílio S S Cunha-Filho, Sônia N Bao, João P F Longo, Josué de Moraes","doi":"10.1021/acsanm.5c02476","DOIUrl":"https://doi.org/10.1021/acsanm.5c02476","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1021/acsanm.4c06757.].</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 22","pages":"11730"},"PeriodicalIF":5.3,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12150259/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144273647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Carbon Quantum Dots: Dimethylglyoxime Thin Film-Based Chemosensors for the Specific Detection of Nickel Ions in Water Resources","authors":"Tanmay Vyas,&nbsp;Mohd Abubakar Sadique,&nbsp;Jyoti Lodhi,&nbsp;Abhijeet Joshi* and Raju Khan*,&nbsp;","doi":"10.1021/acsanm.5c0087210.1021/acsanm.5c00872","DOIUrl":"https://doi.org/10.1021/acsanm.5c00872https://doi.org/10.1021/acsanm.5c00872","url":null,"abstract":"<p >This study presents the development of carbon quantum dot (CQDs)–dimethylglyoxime (DMG) thin film-based chemosensors for the sensitive and selective detection of nickel ions (Ni²⁺) in water resources. These sensors leveraged a dual sensing strategy that combined optical and electrochemical techniques for enhanced accuracy and reliability. The CQDs-DMG thin film was characterized using various techniques, including ultraviolet–visible (UV-vis) spectroscopy, differential pulse voltammetry (DPV), cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), and transmission electron microscopy (TEM). The sensors demonstrated high sensitivity and selectivity toward Ni²⁺ with low detection limits of 0.36 ppm (optical) and 0.29 ppm (electrochemical), achieving a rapid response within 1 min. Spike and recovery studies were conducted using real water samples from the Kshipra and Narmada Rivers, as well as tap water, demonstrating the sensor’s applicability in real-world scenarios. The sensor’s performance was validated by comparison with standard microwave plasma-mediated atomic emission spectroscopy (MP-AES) analysis, exhibiting over 95% accuracy. This innovative dual sensing platform offers a promising solution for the rapid, on-site, and point-of-care detection of Ni²⁺ in water resources, contributing to improved environmental monitoring and management.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 23","pages":"11811–11822 11811–11822"},"PeriodicalIF":5.3,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144269479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced Room-Temperature NH3-Sensing Performance of Ti3C2Tx MXene Decorated with CeO2 Nanoparticles","authors":"Lizhai Zhang*,&nbsp;Jiayuan Xu,&nbsp;Dingyuan Wang,&nbsp;Xinyu Lei,&nbsp;Henghui Sun,&nbsp;Yuhong Huang,&nbsp;Fei Ma,&nbsp;Taotao Ai* and Paul K. Chu*,&nbsp;","doi":"10.1021/acsanm.5c0172110.1021/acsanm.5c01721","DOIUrl":"https://doi.org/10.1021/acsanm.5c01721https://doi.org/10.1021/acsanm.5c01721","url":null,"abstract":"<p >2D MXenes have garnered enormous interest in the field of gas sensing. Unfortunately, the low stability, long recovery time, poor selectivity, and vulnerability to oxidation have hampered further development. Herein, Ti₃C₂T_<i>x</i> MXene is incorporated with CeO₂ nanoparticles to improve the detection of NH₃. Compared with Ti₃C₂T_<i>x</i> and CeO₂, the response of composite to 10 ppm of NH₃ is enhanced by 180% and 714% at room temperature, respectively, in addition to the excellent selectivity, fast response, and recovery rate. Based on the first-principles calculation, the CeO₂ nanoparticles form a multifunctional passivation layer to shield the MXene from oxidative degradation and also provide ample active sites to adsorb NH₃ gas to enhance the sensing ability. The results reveal an effective means of designing and developing high-performance room-temperature ammonia sensors.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 23","pages":"12090–12099 12090–12099"},"PeriodicalIF":5.3,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144269492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comprehensive Comparison among Capacitive, Thermodynamic, and Drift–Diffusion Models for Steady-State Responses of Nanostructured Organic Electrochemical Transistors","authors":"Andres Unigarro,&nbsp; and ,&nbsp;Florian Günther*,&nbsp;","doi":"10.1021/acsanm.5c0210110.1021/acsanm.5c02101","DOIUrl":"https://doi.org/10.1021/acsanm.5c02101https://doi.org/10.1021/acsanm.5c02101","url":null,"abstract":"<p >Organic electrochemical transistors (OECTs) have garnered significant interest in organic electronics due to their fast response, high transconductance, low operating voltage, and versatile fabrication processes. Despite their successful application in various devices, the theoretical understanding of OECTs remains incomplete, particularly regarding the nanoscale interaction between ionic and electronic transport within the organic mixed ionic–electronic conductors (OMIECs) used in these devices. This work introduces a drift–diffusion model that addresses the limitations of existing theoretical frameworks. An analytical expression for the steady-state current in the OECTs is derived, which accounts for both electrical parameters (e.g., gate and drain voltages) and material properties (e.g., salt concentration in the electrolyte). The applicability of our model is validated through comparison with experimental data, revealing new insights into the interplay of various factors affecting the OECT performance. Additionally, we revisit and extend the well-established Bernards–Malliaras (BM) model to cover a broader range of operating conditions, as well as a thermodynamic model. We show that correct usage of the theoretical formulas yields agreement with experimental curves for all presented models, rendering the match itself an insufficient proof of the underlying theory. We set up interconversion formulas between the parameters of the different model approaches and analyze what this implies for their meaning, especially because all show good agreement with the experiment, although based on quite different fundamentals. This comparative analysis provides a deeper understanding of how different components contribute to device operation, offering guidance for the targeted optimization of OECT materials and design with a focus on the exploiting nanoscale phenomena.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 23","pages":"12329–12341 12329–12341"},"PeriodicalIF":5.3,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsanm.5c02101","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144269491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecularly Imprinted Electrochemical Sensor Based on Magnetic Mesoporous Nanocarriers for Sensitive Detection of Tetrabromobisphenol A","authors":"Yanming Shao*,&nbsp;Mengyi Kang,&nbsp;Huanran Feng,&nbsp;Caifeng Hao,&nbsp;Xuan Rong,&nbsp;Huanhuan Zhao,&nbsp;Wenli Ma,&nbsp;Wenli Peng and Yunhe Li*,&nbsp;","doi":"10.1021/acsanm.5c0021510.1021/acsanm.5c00215","DOIUrl":"https://doi.org/10.1021/acsanm.5c00215https://doi.org/10.1021/acsanm.5c00215","url":null,"abstract":"<p >Tetrabromobisphenol A (TBBPA) residues are commonly found in sediments, soil, and sewage, necessitating the development of sensitive methods for its detection in environmental samples due to its potential cytotoxicity and hepatotoxicity. A molecularly imprinted electrochemical sensor, incorporating a magnetic surface molecularly imprinted polymer (SMIP) and an MXene/Au nanocomposite, has been designed for the selective detection of TBBPA. The synergistic effect between MXene and Au nanoparticles significantly enhances the electrochemical signal, thereby resulting in superior sensitivity of the sensor. SMIP was prepared by surface-initiated reversible addition–fragmentation chain transfer polymerization with magnetic mesoporous nanosilica (Fe₃O₄@mSiO₂) as the carrier. Magnetic mesoporous SiO₂ nanoparticles, which combine the advantages of magnetic responsiveness and high specific surface area, not only facilitate the efficient separation of imprinted polymers from liquid mediums under the influence of an external magnetic field but also provide more imprinting sites for SMIP, significantly improving the recognition efficiency. The glassy carbon electrode was sequentially modified with Fe₃O₄@mSiO₂@SMIP and the MXene/Au nanocomposite to achieve specific recognition sites and increased response in electrochemical signals. Density functional theory was employed to optimize the functional monomer and the molar ratio between the template molecule and functional monomer. In addition, variables like pH and incubation time were also optimized to achieve the best detection performance. The current response was linear with TBBPA concentration ranging from 1–4500 nM. The detection limit of the sensor is 0.83 nM. The prepared sensor was successfully used to detect TBBPA in water samples with the recovery ranging from 96.0% to 104.0%. The results indicate that the sensor has wide prospects in the detection of TBBPA in tap water and river water.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 23","pages":"11786–11799 11786–11799"},"PeriodicalIF":5.3,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144269952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pd Supported on CeO2 Nanostructures Prepared by Planetary Ball Milling under a Modified Atmosphere for Catalytic Oxidation of CO","authors":"Enrique Marín,&nbsp;Xavier Vendrell and Jordi Llorca*,&nbsp;","doi":"10.1021/acsanm.5c0176910.1021/acsanm.5c01769","DOIUrl":"https://doi.org/10.1021/acsanm.5c01769https://doi.org/10.1021/acsanm.5c01769","url":null,"abstract":"<p >Pd catalysts supported on CeO₂ (1 wt % Pd) were synthesized using dry mechanochemical and incipient wetness impregnation methods. The mechanochemical synthesis was conducted in a planetary ball mill for 10 min with YSZ milling jar and balls at velocities ranging from 100 to 1000 rpm under various atmospheres (air, N₂, O₂, and 5% H₂/N₂). Catalysts were evaluated for their performance in the CO oxidation reaction and characterized at the nanoscale using Raman spectroscopy, XPS, XRD, H₂-TPR, XRF, nitrogen adsorption/desorption, and HAADF-STEM-EDX. Increased catalytic activity was observed in samples milled at lower velocities (100–250 rpm) in air, outperforming that of the conventional sample prepared by impregnation. This improvement appears to be attributed to changes in the surface nanostructure related to the metal–support interaction rather than the presence of oxygen vacancies. XPS revealed a higher concentration of PdO_<i>x</i>-Ce species in the most active milled sample, suggesting this as a reason for its superior catalytic performance. On the other hand, HAADF-STEM-EDX showed the presence of 2–3 nm Pd nanoparticles as well as Pd atoms/clusters anchored on crystalline ceria in the most active milled sample. Samples milled at high velocity (850–1000 rpm) showed a high degree of structural defects in the ceria crystallites and increased Ce³⁺ species, but their catalytic performance was lower than the samples milled at low velocity. This study highlights the impact of milling conditions on the nanostructure and catalytic properties of Pd/CeO₂ catalysts, with low-velocity milling emerging as a promising approach for enhancing catalytic activity.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 23","pages":"12151–12163 12151–12163"},"PeriodicalIF":5.3,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsanm.5c01769","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144269953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metal-Reduction-Triggered Red Luminescence Quenching in Eu3+-Doped Bi2MoO6 Nanophosphors for H2S Gas Detection","authors":"Taisei Hangai,&nbsp;Takuya Hasegawa*,&nbsp;Yibei Xue,&nbsp;Ayahisa Okawa,&nbsp;Tom Ichibha,&nbsp;Kenta Hongo,&nbsp;Ryo Maezono,&nbsp;Sun Woog Kim,&nbsp;Tomoyo Goto,&nbsp;Yasushi Sato and Shu Yin,&nbsp;","doi":"10.1021/acsanm.5c0175210.1021/acsanm.5c01752","DOIUrl":"https://doi.org/10.1021/acsanm.5c01752https://doi.org/10.1021/acsanm.5c01752","url":null,"abstract":"<p >Luminescence-based gas indicators, which detect gases by monitoring luminescence modulation, have attracted increasing interest due to advancement in technologies of LED and detectors. These indicators provide intuitive visual confirmation of gas presence. In this study, we focused on Eu³⁺-doped Bi₂MoO₆ (BMO:Eu) nanophosphors for the luminescent-based gas detection of hydrogen sulfide (H₂S). BMO:Eu nanophosphors were synthesized using a hydrothermal method to achieve nanoscale morphology, which enhances gas adsorption capacity through an increased surface area. The synthesized BMO:Eu exhibited characteristic red luminescence originating from Eu³⁺ ions. Upon exposure to 500 ppm of H₂S, the red luminescence intensity decreased by approximately 42%, and the extent of quenching showed clear dependence on the H₂S concentration (10–500 ppm), indicating that BMO:Eu can quantitatively detect H₂S. X-ray diffraction patterns revealed lattice expansion after exposure to H₂S, while diffuse reflectance spectra showed a reduction in reflectance in the visible range. Density functional theory calculations indicated that reduced reflectance was due primarily to the reduction of Bi³⁺ and Mo⁶⁺ in BMO:Eu, rather than oxygen substitution by sulfur. X-ray photoelectron spectroscopy confirmed the presence of Bi²⁺ and Mo⁵⁺ species, elucidating that the observed luminescence quenching was due to these reduction processes. Moreover, in situ photoluminescence lifetime measurements showed a decrease in lifetime from 0.76 (before exposure) to 0.62 ms (after exposure), demonstrating that quenching occurred via the formation of nonradiative recombination centers.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 23","pages":"12130–12139 12130–12139"},"PeriodicalIF":5.3,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsanm.5c01752","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144269869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bifunctional Porous Carbon Nanofibers as Cathode Materials and Anode Protection Layers for Zinc-Ion Hybrid Supercapacitors","authors":"Bo Cui,&nbsp;Xianhong Gong,&nbsp;Zhengguang Pan,&nbsp;Xia Wang,&nbsp;Haowen Luo,&nbsp;Xiang Ke,&nbsp;Rui Yang,&nbsp;Chunliang Yang and Guiming Xie*,&nbsp;","doi":"10.1021/acsanm.5c0150010.1021/acsanm.5c01500","DOIUrl":"https://doi.org/10.1021/acsanm.5c01500https://doi.org/10.1021/acsanm.5c01500","url":null,"abstract":"<p >Zinc-ion hybrid supercapacitors (ZISCs) have attracted much attention due to their great potential for safe, high-power, and wearable energy storage but are often limited by the uncontrolled growth of zinc anode dendrites, harmful side reactions, and lower energy density. The paper proposes that hierarchical porous nitrogen-doped carbon nanofibers (HPNCFs) with tightly entangled three-dimensional (3D) networks can be prepared by the carbonization of nanoscale zeolite imidazolium ester backbone (ZIF-67) particles embedded in polyacrylonitrile via an electrostatic spinning technique. The obtained HPNCFs were used as both cathode materials and zinc anode protection layers for ZISCs. The ZISCs based on HPNCF electrodes possessed a specific capacitance of 240 F g^–1 at 1 A g^–1 and an energy density of 80.1 Wh kg^–1 at a power density of 775.2 W kg^–1, maintaining an initial capacity of 99.58% and a Coulombic efficiency of nearly 100% after 50,000 cycles. Additionally, the 3D network hierarchical porous pore structure of HPNCFs can reduce the structural stress and inhibit the growth of Zn dendrites by spatially homogenizing the flux of Zn²⁺ to accelerate the ion transport rate. The HPNCFs provided corrosion protection for the zinc anodes and regulated the nucleation/growth of zinc, thus achieving a long-term stability of over 1200 h. This work provides a strategy for achieving flexible ZISCs with low cost and high performance.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 23","pages":"11965–11975 11965–11975"},"PeriodicalIF":5.3,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144269880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Ultrabright Lanthanide-Doped Luminescent Nanotag for a Smartphone-Based Visual and Portable Lateral Flow Immunoassay of Procalcitonin and Rapid Diagnosis of Bacterial Infection","authors":"Qingwei Song,&nbsp;Yu Lu,&nbsp;Yang Liu,&nbsp;Sihua Qian,&nbsp;Yufeng Liao,&nbsp;A.-Xiang Han,&nbsp;Yunwei Wei*,&nbsp;Kaizhe Wang*,&nbsp;Jianping Zheng* and Yuhui Wang*,&nbsp;","doi":"10.1021/acsanm.5c0156510.1021/acsanm.5c01565","DOIUrl":"https://doi.org/10.1021/acsanm.5c01565https://doi.org/10.1021/acsanm.5c01565","url":null,"abstract":"<p >The lateral flow immunoassay (LFIA), as a popular point-of-care-testing (POCT) technology, has attracted increasing attention, but its analytical performance, especially detection sensitivity, relies on the photophysical properties of the nanotags used. The exploitation of high-performance, robust tags featuring facile fabrication and excellent water solubility remains a great challenge. Herein, we reported a one-pot hydrothermal preparation of diverse polymers (e.g., PAA, PEI, and PVA)-modified YVO₄:Eu nanoparticles (NPs). The polymer-coated YVO₄:Eu NPs revealed abundant surface functional groups (e.g., carboxyl, amino, and hydroxyl), good water solubility, excellent colloidal stability, and strong red emission (absolute quantum yield over 50%). To demonstrate their potential in biolabeling, a routine sandwich LFIA was designed for quick detection of procalcitonin (PCT) using PAA-YVO₄:Eu as the nanotags. Through the luminescence image collection and the corresponding RGB color value transformation, the LFIA test strips were applied for a smartphone-based portable and quantitative detection of PCT (0.2–50 ng/mL) with a limit of detection of 0.06 ng/mL in buffer. Especially, the same quantitative fitting was obtained in human serum with a slightly higher detection limit (0.16 ng/mL), demonstrating high robustness of the test strips in a complex biological matrix. For a clinical validation, in comparison with the chemiluminescent immunoassay, the proposed test strips revealed a good analytical performance (sensitivity: 88.9%, specificity: 95.2%, κ value: 0.83). This work also provides an opportunity to build versatile LFIA platforms for other targets using the developed YVO₄:Eu probes.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 23","pages":"12011–12020 12011–12020"},"PeriodicalIF":5.3,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144269475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}