New Journal of Chemistry最新文献

Facile synthesis of a nickel-quinizarin metal coordination compound as a binder-free electrode for efficient alkaline oxygen evolution reaction. 镍-喹啉金属配位化合物的简单合成及其作为高效碱析氧反应的无粘结剂电极。

IF 2.6 3区化学

New Journal of Chemistry Pub Date : 2026-07-29 eCollection Date: 2026-09-14 DOI: 10.1039/d6nj01583b

Rafia Nimal, Stuart M Clarke, Anna J Warren, Afzal Shah, Muhammad Siddiq, Shaoliang Guan

{"title":"Facile synthesis of a nickel-quinizarin metal coordination compound as a binder-free electrode for efficient alkaline oxygen evolution reaction.","authors":"Rafia Nimal, Stuart M Clarke, Anna J Warren, Afzal Shah, Muhammad Siddiq, Shaoliang Guan","doi":"10.1039/d6nj01583b","DOIUrl":"10.1039/d6nj01583b","url":null,"abstract":"In this work, we present the first systematic study of a metal coordination compound (MCC) based on nickel and 1,4-dihydroxyanthraquinone (quinizarin) as an OER catalyst. The nickel-quinizarin complex referred to as NiQ was synthesized using a facile solvothermal route and a crystalline product was obtained that exhibited excellent structural integrity. Structural data of the as-prepared crystals were obtained by synchrotron microcrystal X-ray diffraction. In the solid state, the Ni(ii) metal centre existed in a distorted octahedral geometry. The complex is further stabilized in the solid state by π-π-stacking interactions between the anthraquinone rings. The redox features of the complex were analysed through cyclic voltammetry (CV), suggesting the involvement of Ni(ii) metal centres in undergoing an oxidation reaction on the application of an anodic sweep. The electrocatalytic performance of NiQ was evaluated by drop casting NiQ slurry on FTO coated glass plates (NiQ@FTO) directly without needing additional binders or conducting particles and running in 1.0 KOH using a three-electrode system. NiQ@FTO achieved an overpotential as low as 300 mV at 10 mA cm-2, surpassing those of many previously reported coordination complex-based OER catalysts. Furthermore, it demonstrated excellent stability over prolonged electrolysis with no significant degradation. The present work not only reports a new class of 1,4-dihydoxyanthraquinone based MCCs as highly active and durable OER catalysts but also offers useful insights into the structure activity relationship, which could be beneficial in future electrocatalysis.","PeriodicalId":95,"journal":{"name":"New Journal of Chemistry","volume":"50 35","pages":"14675-14687"},"PeriodicalIF":2.6,"publicationDate":"2026-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13573823/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148965846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Crystalline coordination polymers of flavonoids with zinc: preparation, solid state structure, and functional properties 黄酮类化合物与锌的结晶配位聚合物：制备、固体结构及功能性质

IF 2.6 3区化学

New Journal of Chemistry Pub Date : 2026-06-12 DOI: 10.1039/D6NJ00840B

Qiuyu Zhang, Hongling Zheng, Siyu Chen and Dejian Huang

引用次数: 0

Serum-stabilized Pickering emulsions as reproducible liquid SERS analyzer for direct metabolic fingerprinting 血清稳定皮克林乳剂作为可重复液体SERS分析仪用于直接代谢指纹图谱

IF 2.6 3区化学

New Journal of Chemistry Pub Date : 2026-06-11 DOI: 10.1039/D6NJ00975A

Ziyu Shao, Yaguang Yin, Kang Xu, Honglin Liu and HongYan Wang

{"title":"Serum-stabilized Pickering emulsions as reproducible liquid SERS analyzer for direct metabolic fingerprinting","authors":"Ziyu Shao, Yaguang Yin, Kang Xu, Honglin Liu and HongYan Wang","doi":"10.1039/D6NJ00975A","DOIUrl":"https://doi.org/10.1039/D6NJ00975A","url":null,"abstract":"Reliable surface-enhanced Raman spectroscopy (SERS) analysis of serum remains challenging due to strong matrix interference and the poor stability and reproducibility of conventional solid substrates. Herein, we report a reproducible, liquid-phase, label-free SERS analyzer based on serum-stabilized Pickering emulsions. In this system, intrinsic serum components regulate interfacial assembly and nanoparticle distribution, enabling direct detection of molecular fingerprints in complex serum matrices. By directly using human serum as the aqueous phase and optimizing emulsification conditions with a n-hexadecane–ethanol mixed oil phase, a robust oil-in-water emulsion substrate was rapidly constructed, exhibiting excellent signal uniformity with relative standard deviations below 7%. The Pickering emulsion effectively enriches serum metabolites while minimizing macromolecular background interference, enabling label-free spectral acquisition. Our analysis reveals significant variations in amino acids, glucose, and purine-related metabolites, underscoring the analyzer's sensitivity for metabolic profiling. Multivariate techniques, including principal component analysis and a feedforward neural network, enhance spectral feature extraction and metabolic state classification. This liquid SERS strategy combines high reproducibility, minimal sample pretreatment, and compatibility with data-driven analysis, establishing a versatile tool for serum metabolite fingerprinting and metabolic studies in complex biofluids.","PeriodicalId":95,"journal":{"name":"New Journal of Chemistry","volume":" 25","pages":" 10387-10391"},"PeriodicalIF":2.6,"publicationDate":"2026-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148336677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A programmable multifunctional DNA hydrogel enabling integrated detection and inactivation of Staphylococcus aureus 一种可编程的多功能DNA水凝胶，能够集成检测和灭活金黄色葡萄球菌

IF 2.6 3区化学

New Journal of Chemistry Pub Date : 2026-06-10 DOI: 10.1039/D6NJ01268J

Wentong Yu, Ziyan Zhao, Chunyuan Huo, Zhiqiang Guo, Xinru Ren, Su Liu, Yu Wang and Jiadong Huang

{"title":"A programmable multifunctional DNA hydrogel enabling integrated detection and inactivation of Staphylococcus aureus","authors":"Wentong Yu, Ziyan Zhao, Chunyuan Huo, Zhiqiang Guo, Xinru Ren, Su Liu, Yu Wang and Jiadong Huang","doi":"10.1039/D6NJ01268J","DOIUrl":"10.1039/D6NJ01268J","url":null,"abstract":"Herein, we report a multifunctional DNA hydrogel (TBDH) platform that integrates the specific detection and efficient inactivation of S. aureus within a single programmable architecture. The platform consists of three core components: an aptamer (Apt) for target recognition, two DNA signaling strands (SA and SB) for fluorescence transduction, and self-assembled antibacterial nanoparticles (TBNPs). Through rational structural integration, these elements are incorporated into a tunable polymeric network, enabling a unified “recognition–reporting–inactivation” function. In the presence of S. aureus, Apt binding triggers hydrogel dissociation, restoring the quenched Cy3 fluorescence and generating a dose-dependent signal with a detection limit of 11 CFU mL−1. Simultaneously, hydrogel collapse induces on-demand release of TBNPs, which exhibit potent antibacterial and anti-biofilm efficacy (>99.9% inactivation) by disrupting bacterial membrane integrity. The TBDH platform demonstrates high specificity, rapid response (90 min), and reliable performance in complex matrices. This work provides an integrated, stimuli-responsive strategy for simultaneous pathogen detection and eradication, offering promising potential for applications in food safety and clinical infection control.","PeriodicalId":95,"journal":{"name":"New Journal of Chemistry","volume":" 25","pages":" 10504-10515"},"PeriodicalIF":2.6,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148305692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A smartphone-integrated colorimetric sensing platform for the detection of tannic acid in beverages using folic acid-functionalized copper nanoclusters nanozyme 基于叶酸功能化铜纳米团簇纳米酶的智能手机集成比色传感平台检测饮料中的单宁酸

IF 2.6 3区化学

New Journal of Chemistry Pub Date : 2026-06-10 DOI: 10.1039/D6NJ00702C

Savarimuthu Monisha and Malaichamy Ilanchelian

{"title":"A smartphone-integrated colorimetric sensing platform for the detection of tannic acid in beverages using folic acid-functionalized copper nanoclusters nanozyme","authors":"Savarimuthu Monisha and Malaichamy Ilanchelian","doi":"10.1039/D6NJ00702C","DOIUrl":"https://doi.org/10.1039/D6NJ00702C","url":null,"abstract":"In the present work, we describe a straightforward method for the synthesis of highly luminescent folic acid-functionalized copper nanoclusters (FA–CuNCs) using folic acid as a stabilizing agent and hydrazine hydrate as a reducing agent. In the presence of hydrogen peroxide (H2O2), the FA–CuNCs drive the oxidation of 3,3′,5,5′-tetramethyl benzidine (TMB) to its blue oxidized state (oxTMB), demonstrating good peroxidase-like activity. Adding tannic acid (TA) dramatically inhibits its catalytic activity making it possible to create a rapid, colorimetric sensing platform for TA. The proposed sensor exhibited notable sensitivity, achieving a low detection limit of 88.5 nM and a wide linear range from 2.00 × 10−7 to 4.00 × 10−6 mol dm−3, showing good selectivity against common interfering ions and biomolecules. This method was made considerably simpler and more portable by combining the colorimetric visibility with RGB color variation analysis based on a smartphone. Furthermore, the successful detection of TA in actual tea and coffee samples validated the method for practical applications. This portable, straightforward, cost effective and selective approach has a lot of potential for practical uses in environmental monitoring and food safety.","PeriodicalId":95,"journal":{"name":"New Journal of Chemistry","volume":" 25","pages":" 10473-10484"},"PeriodicalIF":2.6,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148336686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Polymetallic sulfide assembly of Cu2S/Ni3S2 grown in situ on Ni foam as a self-supported electrode and electrocatalyst for high-efficiency non-enzymatic glucose sensing 在泡沫镍上原位生长的Cu2S/Ni3S2多金属硫化物组装作为高效非酶葡萄糖传感的自支撑电极和电催化剂

IF 2.6 3区化学

New Journal of Chemistry Pub Date : 2026-06-10 DOI: 10.1039/D6NJ01201A

Jiahao Huang, Zichang Yang, Wu Li, Zhiyong Wang and Chunxiang Zhu

{"title":"Polymetallic sulfide assembly of Cu2S/Ni3S2 grown in situ on Ni foam as a self-supported electrode and electrocatalyst for high-efficiency non-enzymatic glucose sensing","authors":"Jiahao Huang, Zichang Yang, Wu Li, Zhiyong Wang and Chunxiang Zhu","doi":"10.1039/D6NJ01201A","DOIUrl":"https://doi.org/10.1039/D6NJ01201A","url":null,"abstract":"A polymetallic sulfide of Cu2S/Ni3S2 is assembled in situ on nickel foam (NF), serving as a self-supported electrode and electrocatalyst for non-enzymatic glucose sensing. Benefiting from interfacial synergistic effects, the Cu2S/Ni3S2/NF composite exhibits outstanding electrocatalytic capability toward glucose oxidation, with a high sensitivity of 22 750 µA mM−1 cm−2, a low limit of detection (LOD) of 0.51 µM, a broad linear detection range of 1 µM–1 mM, and good selectivity against interfering species. Density functional theory (DFT) calculations of the Cu2S/Ni3S2 heterojunction are performed to reveal the density of states (DOS) and charge density difference. Effective interfacial electron transfer between Cu2S and Ni3S2 modulates the electronic structure, thereby enhancing electrocatalytic activity. The optimal d-band centers (dbc) of Cu and Ni in Cu2S/Ni3S2 are beneficial for the promotion of glucose sensing sensitivity. This work provides an efficient strategy for fabricating polymetallic sulfides for application in next-generation non-enzymatic glucose sensing.","PeriodicalId":95,"journal":{"name":"New Journal of Chemistry","volume":" 25","pages":" 10588-10599"},"PeriodicalIF":2.6,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148336703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis, crystal structures, optical properties and quantum chemical studies of novel organic–inorganic materials based on polyoxodecavanadate 聚十氰酸氧基新型有机-无机材料的合成、晶体结构、光学性质及量子化学研究

IF 2.6 3区化学

New Journal of Chemistry Pub Date : 2026-06-10 DOI: 10.1039/D6NJ01321J

Jawher Makhlouf, Kandasamy Saravanan, Muhammad Ashfaq, Laurent Jouffret, Youness El Bakri, Werner Kaminsky, Sabir Ali Siddique, Aseel Smerat, Adem Kilani and Rashad Al-Salahi

{"title":"Synthesis, crystal structures, optical properties and quantum chemical studies of novel organic–inorganic materials based on polyoxodecavanadate","authors":"Jawher Makhlouf, Kandasamy Saravanan, Muhammad Ashfaq, Laurent Jouffret, Youness El Bakri, Werner Kaminsky, Sabir Ali Siddique, Aseel Smerat, Adem Kilani and Rashad Al-Salahi","doi":"10.1039/D6NJ01321J","DOIUrl":"https://doi.org/10.1039/D6NJ01321J","url":null,"abstract":"The reaction between decavanadate clusters and organic cations has attracted intensive research interest due to the interesting properties of the resulting materials. The asymmetric unit of their structure consists of a complete dihydrogen decavanadate anion ([H2V10O28]−4), four organic 1-vinyl-1H-imidazol-3-ium cations (4[C5H7N2]+1), and four water molecules. The stability of the crystal arises from O–H⋯O, N–H⋯O and C–H⋯O bonding, with structural stabilization largely attributed to water molecules. Crystals have been grown by slow evaporation of the solution at room temperature. The compound has been chemically and spectroscopically characterized by a combination of elemental and thermal analyses, together with IR spectroscopy, and its structure was elucidated by X-ray diffraction. Density functional theory calculations combined with Hirshfeld surface, QTAIM, NCI, NBO, and frontier molecular orbital analyses reveal that the electronic structure of the hybrid system is governed by organic-to-inorganic charge transfer, with the organic moiety acting as an electron donor and the polyoxodecavanadate cluster serving as an electron acceptor. The combined experimental and theoretical results provide a coherent description of the bonding, noncovalent interactions, and electronic properties of the title compound.","PeriodicalId":95,"journal":{"name":"New Journal of Chemistry","volume":" 25","pages":" 10553-10566"},"PeriodicalIF":2.6,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148336700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Superior energy storage performance of MOF/PANI nanocomposites: toward sustainable supercapacitors MOF/PANI纳米复合材料卓越的储能性能：迈向可持续超级电容器

IF 2.6 3区化学

New Journal of Chemistry Pub Date : 2026-06-10 DOI: 10.1039/D6NJ00762G

Deepa B. Bailmare, Priti A. Mangrulkar, Shreerang Vyawahare, Santoshi Biswal and Abhay D. Deshmukh

{"title":"Superior energy storage performance of MOF/PANI nanocomposites: toward sustainable supercapacitors","authors":"Deepa B. Bailmare, Priti A. Mangrulkar, Shreerang Vyawahare, Santoshi Biswal and Abhay D. Deshmukh","doi":"10.1039/D6NJ00762G","DOIUrl":"https://doi.org/10.1039/D6NJ00762G","url":null,"abstract":"The urgent demand for sustainable energy storage has driven the development of devices that combine high energy density with excellent power delivery. Supercapacitors, regarded as hybrid energy storage systems with characteristics of both batteries and capacitors, have emerged as attractive candidates for next-generation applications. The key challenge is to design electrode materials that exhibit high capacity, energy density, and durability. In this study, we report a metal–organic framework/polyaniline (MOF/PANI) nanocomposite electrode, engineered to overcome the poor conductivity of MOFs while leveraging their high surface area and porosity. The incorporation of conductive PANI enhances charge transport and structural integrity, enabling superior electrochemical performance. The MOF/PANI electrode achieves a specific capacity of 525.68 C g−1 at 2 A g−1, with 95.3% capacity retention after 4000 cycles. An asymmetric supercapacitor device fabricated from the nanocomposite delivers a specific capacity of 401.44 C g−1 at 0.5 A g−1 current density, along with an energy density of 72.48 Wh kg−1 at a power density of 1299.99 W kg−1. Notably, the device maintains 96% capacity retention over 50k cycles, reflecting outstanding durability. These results highlight the MOF/PANI nanocomposite as a high-performance electrode material, demonstrating significant potential for sustainable supercapacitor applications that bridge the gap between batteries and supercapacitors.","PeriodicalId":95,"journal":{"name":"New Journal of Chemistry","volume":" 25","pages":" 10516-10528"},"PeriodicalIF":2.6,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148336698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bifunctional fluorescent iron-doped carbon dot-based nanozyme for highly sensitive dual-mode cascade detection of d-galactose 基于双功能荧光铁掺杂碳点纳米酶的高灵敏度双模级联检测d-半乳糖

IF 2.6 3区化学

New Journal of Chemistry Pub Date : 2026-06-09 DOI: 10.1039/D6NJ01090C

Lei Wang, Weiping Liu, Dan Qiu, Xingju Li, Yawen Lin and Yan Zhao

{"title":"Bifunctional fluorescent iron-doped carbon dot-based nanozyme for highly sensitive dual-mode cascade detection of d-galactose","authors":"Lei Wang, Weiping Liu, Dan Qiu, Xingju Li, Yawen Lin and Yan Zhao","doi":"10.1039/D6NJ01090C","DOIUrl":"https://doi.org/10.1039/D6NJ01090C","url":null,"abstract":" D-Galactose (D-Gal) is a monosaccharide crucial for various physiological processes in organisms. Abnormal variations in its levels are strongly correlated with several inherited metabolic conditions, including galactosemia. Thus, creating efficient, sensitive, and accurate detection methods for D-Gal is crucial for the early diagnosis of diseases. Herein, a novel multifunctional nanozyme derived from iron-doped carbon dots (Fe-CDs) was developed, integrating intrinsic fluorescence with robust peroxidase-like properties. Galactose oxidase catalyzes the oxidation of D-Gal to generate hydrogen peroxide (H2O2). The Fe-CD nanozyme facilitates the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) by the resulting H2O2, ultimately producing blue oxidized TMB (oxTMB) with a distinct absorption peak at 652 nm. Simultaneously, oxTMB quenches the fluorescence of Fe-CDs at 526 nm through fluorescence resonance energy transfer, enabling dual-mode fluorescence-colorimetric detection. The limits of detection were determined to be 0.25 µM (fluorescence mode) and 19 µM (colorimetric mode), with corresponding linear ranges of 0.001–120 mM and 0.1–100 mM, respectively. Additionally, the sensing platform was successfully employed for the quantitative analysis of D-Gal in human serum samples. The fluorometric method achieved average recoveries of 95.6–102.6%, while the colorimetric method gave recoveries of 97.5–102.8%, exhibiting outstanding selectivity and reliability. This study provides a novel cascade system for D-Gal detection, highlighting its potential applications in the fields of biomedicine and biosensing.","PeriodicalId":95,"journal":{"name":"New Journal of Chemistry","volume":" 25","pages":" 10438-10447"},"PeriodicalIF":2.6,"publicationDate":"2026-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148336682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tailoring diacid carbon chains of precursors to boost the peroxidase activity of carbon dot nanozymes for dual-mode glyphosate detection 裁剪前体的二酸碳链以提高碳点纳米酶的过氧化物酶活性，用于双模式草甘膦检测

IF 2.6 3区化学

New Journal of Chemistry Pub Date : 2026-06-09 DOI: 10.1039/D6NJ01352J

Xiaomei Li, Yi Feng, Xue Huang, Wencai Jiang, Guilin Zou, Shiyu Long, Zhibo Hou, Yan Zhao and Guoqi Zhang

{"title":"Tailoring diacid carbon chains of precursors to boost the peroxidase activity of carbon dot nanozymes for dual-mode glyphosate detection","authors":"Xiaomei Li, Yi Feng, Xue Huang, Wencai Jiang, Guilin Zou, Shiyu Long, Zhibo Hou, Yan Zhao and Guoqi Zhang","doi":"10.1039/D6NJ01352J","DOIUrl":"https://doi.org/10.1039/D6NJ01352J","url":null,"abstract":" Background: carbon dot nanozymes (CDszymes) hold significant promise for sensing applications due to their excellent water solubility and intrinsic fluorescence. However, conventional approaches for synthesizing CDszymes with high peroxidase-like (POD) activity remain largely empirical, relying on trial-and-error precursor screening, which limits rational design and optimization. Results: carbon dot nanoenzymes (CDszymes) demonstrate potential applications in nanoenzymatic sensing due to their excellent solubility and intrinsic fluorescence. However, conventional methods for synthesizing CDszymes with high peroxidase (POD) activity rely on empirical precursor screening. In this study, CDszymes with optimal POD activity were rationally designed by regulating the carbon chain length of dicarboxylic acids. Among the six synthesized CDszymes, ethanedioic acid-derived CDszymes-2 exhibited the highest POD activity, which catalyzes the oxidation of TMB by H2O2 to produce blue oxidized TMB (oxTMB), alongside fluorescence quenching via an inner filter effect. Utilizing glyphosate's (GLY) inhibition of acetylcholinesterase (AChE), a dual-mode colorimetric/fluorescent sensing platform was established, attaining detection limits of 13 ng mL−1 (colorimetric) and 7 ng mL−1 (fluorescent). Dual-mode sensing was successfully applied to detect GLY in fruit and vegetable samples, demonstrating potential for ultrasensitive trace-level pesticide detection in agricultural products.","PeriodicalId":95,"journal":{"name":"New Journal of Chemistry","volume":" 24","pages":" 10269-10277"},"PeriodicalIF":2.6,"publicationDate":"2026-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148285310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0