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Decompression sickness type II and patent foramen ovale: when a common congenital anomaly becomes a life-threatening risk. 减压病II型和卵圆孔未闭：当一个常见的先天性异常成为危及生命的风险。
IF 2.9
Medical Gas Research Pub Date : 2026-06-01 Epub Date: 2025-08-18 DOI: 10.4103/mgr.MEDGASRES-D-25-00065
Alejandro Fernandez-Cisneros
{"title":"Decompression sickness type II and patent foramen ovale: when a common congenital anomaly becomes a life-threatening risk.","authors":"Alejandro Fernandez-Cisneros","doi":"10.4103/mgr.MEDGASRES-D-25-00065","DOIUrl":"10.4103/mgr.MEDGASRES-D-25-00065","url":null,"abstract":"","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"16 2","pages":"184-185"},"PeriodicalIF":2.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144874050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Old theory, new evidence: inhalational anesthetics disrupt a collective quantum state of intraneuronal microtubules to cause unconsciousness. 旧理论，新证据：吸入麻醉剂破坏了神经元内微管的集体量子态，从而导致无意识。
IF 2.9
Medical Gas Research Pub Date : 2026-06-01 Epub Date: 2025-08-18 DOI: 10.4103/mgr.MEDGASRES-D-25-00111
Michael C Wiest
{"title":"Old theory, new evidence: inhalational anesthetics disrupt a collective quantum state of intraneuronal microtubules to cause unconsciousness.","authors":"Michael C Wiest","doi":"10.4103/mgr.MEDGASRES-D-25-00111","DOIUrl":"10.4103/mgr.MEDGASRES-D-25-00111","url":null,"abstract":"","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"16 2","pages":"182-183"},"PeriodicalIF":2.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144874076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oxygen therapy in ischemic colitis. 缺血性结肠炎的氧疗。
IF 2.9
Medical Gas Research Pub Date : 2026-06-01 Epub Date: 2025-08-18 DOI: 10.4103/mgr.MEDGASRES-D-25-00093
Jamil Nasrallah, Ali Dheyaa Marsool, Alaa Mohammed Oudah, Abdulrahman Abbas Al-Husseini, Jobran Toami, Hiba Hamdar
{"title":"Oxygen therapy in ischemic colitis.","authors":"Jamil Nasrallah, Ali Dheyaa Marsool, Alaa Mohammed Oudah, Abdulrahman Abbas Al-Husseini, Jobran Toami, Hiba Hamdar","doi":"10.4103/mgr.MEDGASRES-D-25-00093","DOIUrl":"10.4103/mgr.MEDGASRES-D-25-00093","url":null,"abstract":"","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"16 2","pages":"178-179"},"PeriodicalIF":2.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144874077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mitochondrial protection role of oxidoreductase-like domain containing 1 in myocardial cells under hypoxia. 含1氧化还原酶样结构域对缺氧心肌细胞线粒体的保护作用。
IF 2.9
Medical Gas Research Pub Date : 2026-06-01 Epub Date: 2025-08-18 DOI: 10.4103/mgr.MEDGASRES-D-24-00117
Yan Yan, Min Dong, Liuyang Tian, Chao Zhu, Xiaojing Zhao
{"title":"Mitochondrial protection role of oxidoreductase-like domain containing 1 in myocardial cells under hypoxia.","authors":"Yan Yan, Min Dong, Liuyang Tian, Chao Zhu, Xiaojing Zhao","doi":"10.4103/mgr.MEDGASRES-D-24-00117","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00117","url":null,"abstract":"<p><p>JOURNAL/mgres/04.03/01612956-202606000-00006/figure1/v/2025-08-18T154854Z/r/image-tiff Although mitochondria and related proteins are essential for mitochondrial preservation, the functions of some of these proteins remain unknown. The novel protein oxidoreductase-like domain containing 1 (OXLD1/C17orf90, UniProtKB Q5BKU9) have attracted our attention because of its correlation with mitochondria. This study revealed a decrease in OXLD1 levels in cardiomyocytes cultured in 1% oxygen for 24 hours. Suppressing OXLD1 increases mitochondrial injury under both normoxic and hypoxic conditions. This is evidenced by decreased mitochondrial membrane potential and increased reactive oxygen species production. Meanwhile, suppressing OXLD1 decreased mitochondrial oxidative phosphorylation. Overexpression of OXLD1 decreased mitochondrial injury under normoxia and hypoxia, as indicated by an increase in the mitochondrial membrane potential and a decrease in reactive oxygen species production. Moreover, overexpression of OXLD1 enhanced mitochondrial oxidative phosphorylation. Additionally, we found that OXLD1 regulates mitochondrial oxidative phosphorylation by affecting mitochondrial complexes I and V. OXLD1 plays a crucial role in protecting cardiomyocytes by improving mitochondrial function under low-oxygen conditions. OXLD1 achieves this protection through interactions with mitochondrial complexes I and V. Therefore, OXLD1 may serve as a new and important regulator of mitochondrial function.</p>","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"16 2","pages":"116-124"},"PeriodicalIF":2.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144874074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plant-derived phenolics as regulators of nitric oxide production in microglia: mechanisms and therapeutic potential. 植物源性酚类物质作为小胶质细胞一氧化氮产生的调节剂：机制和治疗潜力。
IF 2.9
Medical Gas Research Pub Date : 2026-06-01 Epub Date: 2025-08-18 DOI: 10.4103/mgr.MEDGASRES-D-25-00058
Naira Sahakyan
{"title":"Plant-derived phenolics as regulators of nitric oxide production in microglia: mechanisms and therapeutic potential.","authors":"Naira Sahakyan","doi":"10.4103/mgr.MEDGASRES-D-25-00058","DOIUrl":"10.4103/mgr.MEDGASRES-D-25-00058","url":null,"abstract":"<p><p>Neuroinflammation plays a critical role in the pathogenesis of neurodegenerative diseases with microglial activation and excessive nitric oxide production contributing significantly to disease progression. Plant-derived phenolic compounds have emerged as promising neuroprotective agents due to their ability to modulate the key signaling pathways, including nuclear factor-κB, mitogen-activated protein kinases, nuclear factor erythroid 2-related factor 2, and phosphoinositide 3-kinase/protein kinase B. These bioactive molecules effectively suppress inducible nitric oxide synthase expression, reduce oxidative and nitrosative stress, and restore immune homeostasis. Additionally, these natural phenolic compounds are able to regulate mitochondrial function and autophagy, further supporting their therapeutic potential in central nervous system disorders. The presented review aimed to explain the key known mechanisms of action of plant-origin phenolics, in order to evaluate their potential in developing treatments and preventing central nervous system diseases.</p>","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"16 2","pages":"169-175"},"PeriodicalIF":2.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144874078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Density Functional Theory calculations employed to describe the transport of medical gases. 密度泛函理论计算用于描述医用气体的传输。
IF 2.9
Medical Gas Research Pub Date : 2026-06-01 Epub Date: 2025-08-18 DOI: 10.4103/mgr.MEDGASRES-D-25-00110
Handriela Hoff de Oliveira Sobrinho, Renato Eising, Ernesto Osvaldo Wrasse
{"title":"Density Functional Theory calculations employed to describe the transport of medical gases.","authors":"Handriela Hoff de Oliveira Sobrinho, Renato Eising, Ernesto Osvaldo Wrasse","doi":"10.4103/mgr.MEDGASRES-D-25-00110","DOIUrl":"10.4103/mgr.MEDGASRES-D-25-00110","url":null,"abstract":"","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"16 2","pages":"180-181"},"PeriodicalIF":2.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144874051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gas-induced spinal cord compression: mechanisms, diagnosis, and treatment of intraspinous pneumorrhachis. 气体引起的脊髓压迫：机制、诊断和治疗棘内气痛。
IF 2.9
Medical Gas Research Pub Date : 2026-06-01 Epub Date: 2025-08-18 DOI: 10.4103/mgr.MEDGASRES-D-25-00004
Xidan Zheng, Shan Wang, Shubei Zhu, Yan Zhang, Debo Yun, Yujiao Yang
{"title":"Gas-induced spinal cord compression: mechanisms, diagnosis, and treatment of intraspinous pneumorrhachis.","authors":"Xidan Zheng, Shan Wang, Shubei Zhu, Yan Zhang, Debo Yun, Yujiao Yang","doi":"10.4103/mgr.MEDGASRES-D-25-00004","DOIUrl":"10.4103/mgr.MEDGASRES-D-25-00004","url":null,"abstract":"<p><p>Gas-induced spinal cord compression, also known as intraspinous pneumorrhachis, is a rare condition in which the presence of gas in the spinal canal generally does not result in any symptoms. However, in certain cases, gas can compress the spinal cord, leading to severe neurological dysfunction. This underscores the importance of early recognition and intervention. Herein, we conduct a comprehensive analysis of the literature on pneumorrhachis by searching databases such as PubMed, ClinicalKey, Web of Science, and CNKI. We discuss the etiology, pathophysiology, clinical manifestations, imaging features, differential diagnosis, treatment strategies, and prognosis of these patients. Our findings indicate that the occurrence of intraspinous pneumorrhachis is associated with various factors, including medical conditions, trauma, and infection. While most cases are limited in extent and resolve spontaneously, a subset of cases may signal a serious underlying condition.</p>","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"16 2","pages":"140-147"},"PeriodicalIF":2.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144874070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison between paravertebral injections of ozone and epidural injections of corticosteroids used in the treatment of lumbosacral pain: scoping review. 椎旁注射臭氧与硬膜外注射皮质类固醇治疗腰骶痛的比较：范围回顾。
IF 2.9
Medical Gas Research Pub Date : 2026-06-01 Epub Date: 2025-08-18 DOI: 10.4103/mgr.MEDGASRES-D-25-00091
Pedro Iván Arias-Vázquez, Rosa Giannina Castillo-Avila, Ricardo Quezada-González, Karen Hernández-Gil, Blanca Gabriela Legorreta-Ramírez, María Antonieta Ramírez-Wakamatzu
{"title":"Comparison between paravertebral injections of ozone and epidural injections of corticosteroids used in the treatment of lumbosacral pain: scoping review.","authors":"Pedro Iván Arias-Vázquez, Rosa Giannina Castillo-Avila, Ricardo Quezada-González, Karen Hernández-Gil, Blanca Gabriela Legorreta-Ramírez, María Antonieta Ramírez-Wakamatzu","doi":"10.4103/mgr.MEDGASRES-D-25-00091","DOIUrl":"10.4103/mgr.MEDGASRES-D-25-00091","url":null,"abstract":"<p><p>Paravertebral ozone injections have been used in the treatment of lumbosacral pain with or without radicular irradiation and have been reported to be effective in reducing pain when compared with placebo, physiotherapy programs or drug treatments; nevertheless, their effectiveness in comparison with minimally invasive procedures using corticosteroids is unknown. The main objective of this review was to explore the role of paravertebral ozone injections in the treatment of lumbosacral pain with radicular irradiation in comparison with minimally invasive procedures using corticosteroids. A systematic search was performed in electronic databases including PubMed, EMBASE, Central Cochrane and Web of Science, from January 2000 to December 2024; for clinical studies that compared paravertebral ozone injections with minimally invasive procedures using corticosteroids in the treatment of lumbosacral pain with radicular irradiation and were performed using the methodology of a scoping review. Four clinical trials met the inclusion criteria and were included in this review, gathering a total of 501 individuals. In the within-group comparison of every study, statistically significant reduction in pain was observed in both interventions. No side effects or serious adverse reactions were reported in the treated patients. Paravertebral ozone injections appear to have a favorable therapeutic effect in reducing pain in the short and medium terms, in individuals with lumbosacral pain with radicular irradiation, and this effect appears to be similar to that of epidural corticosteroid injections. No definitive recommendations are possible, for more clinical trials are needed to conduct meta-analytic reviews that clarify the results of this comparison.</p>","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"16 2","pages":"133-139"},"PeriodicalIF":2.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144874048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum: Gas mixture in noninvasive ventilation. 勘误：无创通气中的气体混合物。
IF 2.9
Medical Gas Research Pub Date : 2026-06-01 Epub Date: 2025-08-18 DOI: 10.4103/mgr.MEDGASRES-D-25-00218
{"title":"Corrigendum: Gas mixture in noninvasive ventilation.","authors":"","doi":"10.4103/mgr.MEDGASRES-D-25-00218","DOIUrl":"10.4103/mgr.MEDGASRES-D-25-00218","url":null,"abstract":"","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"16 2","pages":"102"},"PeriodicalIF":2.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144874049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of hydrogen-oxygen inhalation on sleep disorders and abnormal mood: a single-blind, randomized controlled trial. 氢氧吸入对睡眠障碍和异常情绪的影响：一项单盲、随机对照试验。
IF 2.9
Medical Gas Research Pub Date : 2026-06-01 Epub Date: 2025-08-18 DOI: 10.4103/mgr.MEDGASRES-D-25-00020
Yu Hong Gao, Jun Chen, Hua Zhong, Qiang Zhao
{"title":"Effect of hydrogen-oxygen inhalation on sleep disorders and abnormal mood: a single-blind, randomized controlled trial.","authors":"Yu Hong Gao, Jun Chen, Hua Zhong, Qiang Zhao","doi":"10.4103/mgr.MEDGASRES-D-25-00020","DOIUrl":"10.4103/mgr.MEDGASRES-D-25-00020","url":null,"abstract":"<p><p>JOURNAL/mgres/04.03/01612956-202606000-00002/figure1/v/2025-08-18T154854Z/r/image-tiff Sleep disorders are associated with various chronic diseases. While hydrogen has anti-inflammatory, antioxidant, and antifibrotic effects and has potential applications in disease management, its impact on sleep disorders remains unclear. This single-blind, randomized controlled clinical trial from September 2022 to July 2023 at the Second Medical Center of the PLA General Hospital and the Affiliated Hospital of Chengde Medical College examined the effect of hydrogen-oxygen on sleep disorders. Sixty-six participants with sleep disorders were randomly divided into a control group and a hydrogen-oxygen group that received nasal gas inhalation for seven days. Sleep quality and mood were assessed using the Pittsburgh Sleep Quality Index, Self-Rating Depression Scale, and Self-Rating Anxiety Scale. An Actiwatch helped evaluate the effects of two kinds of gas inhalation on total sleep time, sleep efficiency, and the wake time of patients with sleep disorders. The control group showed no significant changes in sleep parameters during treatment, whereas the hydrogen-oxygen group showed significant improvements in total sleep time and sleep efficiency on days 3, 5, and 7 and significant reductions in wake time on days 3 and 7. Compared with those in the control group, the total sleep time was greater and the wake time was lower in the hydrogen-oxygen group. After 7 days, the scores of the Pittsburgh Sleep Quality Index and Self-Rating Depression Scale in the hydrogen-oxygen group were lower than those in the control group, whereas the Self-Rating Anxiety Scale scores did not differ significantly. Hydrogen-oxygen therapy effectively improved sleep disorders by reducing wake time, relieving psychological stress, and enhancing sleep quality. The study was registered in the Chinese Clinical Trial Registry (registration No. ChiCTR2400084103).</p>","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"16 2","pages":"98-102"},"PeriodicalIF":2.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144874052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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