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Corrigendum to "A CRISPR-Cas12a-mediated dual-mode luminescence and colorimetric nucleic acid biosensing platform based on upconversion nanozyme" [Biosens. Bioelectron. 270 (2025) 116963]. “基于上转换纳米酶的crispr - cas12a介导的双模式发光和比色核酸生物传感平台”的勘误表[Biosens]。生物电子学学报,2015(5):391 - 391。
IF 10.7 1区 生物学
Biosensors and Bioelectronics Pub Date : 2025-11-01 Epub Date: 2025-07-05 DOI: 10.1016/j.bios.2025.117738
Jiaxiang Yan, Bohan Yin, Qin Zhang, Chuanqi Li, Jiareng Chen, Yingying Huang, Jianhua Hao, Changqing Yi, Yu Zhang, Siu Hong Dexter Wong, Mo Yang
{"title":"Corrigendum to \"A CRISPR-Cas12a-mediated dual-mode luminescence and colorimetric nucleic acid biosensing platform based on upconversion nanozyme\" [Biosens. Bioelectron. 270 (2025) 116963].","authors":"Jiaxiang Yan, Bohan Yin, Qin Zhang, Chuanqi Li, Jiareng Chen, Yingying Huang, Jianhua Hao, Changqing Yi, Yu Zhang, Siu Hong Dexter Wong, Mo Yang","doi":"10.1016/j.bios.2025.117738","DOIUrl":"10.1016/j.bios.2025.117738","url":null,"abstract":"","PeriodicalId":259,"journal":{"name":"Biosensors and Bioelectronics","volume":" ","pages":"117738"},"PeriodicalIF":10.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144566883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum to "Development of a universal one-pot CRISPR assay based on multifunctional tagged primer eliminating unstable crRNA input and PAM dependency for point-of-care detection of bacterial infections" [Biosens. Bioelectron. 287 (2025) 117718]. “基于多功能标记引物消除不稳定的crRNA输入和PAM依赖,用于即时检测细菌感染的通用一罐CRISPR测定的开发”的勘误表[Biosens]。生物电子学学报,2004,12(2):357 - 357。
IF 10.7 1区 生物学
Biosensors and Bioelectronics Pub Date : 2025-11-01 Epub Date: 2025-07-04 DOI: 10.1016/j.bios.2025.117742
Xiaofan Zhu, Jingran Jiao, Qun Ni, Li Yao, Yule Zhang, Kaiyong Liu, Lin Huang, Qingli Bo, Panzhu Qin
{"title":"Corrigendum to \"Development of a universal one-pot CRISPR assay based on multifunctional tagged primer eliminating unstable crRNA input and PAM dependency for point-of-care detection of bacterial infections\" [Biosens. Bioelectron. 287 (2025) 117718].","authors":"Xiaofan Zhu, Jingran Jiao, Qun Ni, Li Yao, Yule Zhang, Kaiyong Liu, Lin Huang, Qingli Bo, Panzhu Qin","doi":"10.1016/j.bios.2025.117742","DOIUrl":"10.1016/j.bios.2025.117742","url":null,"abstract":"","PeriodicalId":259,"journal":{"name":"Biosensors and Bioelectronics","volume":" ","pages":"117742"},"PeriodicalIF":10.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144564200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ferrocene derivatives constructed Prussian blue analogs for colorimetric detection of hydrogen peroxide and glucose. 二茂铁衍生物构建的普鲁士蓝类似物用于过氧化氢和葡萄糖的比色检测。
IF 10.7 1区 生物学
Biosensors and Bioelectronics Pub Date : 2025-11-01 Epub Date: 2025-06-25 DOI: 10.1016/j.bios.2025.117714
Yue Tong, Qian Liu, Dan Yang, Chunze Zhang, Yi Xiao, Mengying Shi, Meng Meng, Huixia Di, Hongmei Gao, Rimo Xi, Yongmei Yin
{"title":"Ferrocene derivatives constructed Prussian blue analogs for colorimetric detection of hydrogen peroxide and glucose.","authors":"Yue Tong, Qian Liu, Dan Yang, Chunze Zhang, Yi Xiao, Mengying Shi, Meng Meng, Huixia Di, Hongmei Gao, Rimo Xi, Yongmei Yin","doi":"10.1016/j.bios.2025.117714","DOIUrl":"10.1016/j.bios.2025.117714","url":null,"abstract":"<p><p>This study reports the rational design of ferrocene-derived Prussian blue analogs (PBAs) as a new class of nanozymes with enhanced catalytic properties. Capitalizing on its high peroxidase-like activity, we developed a colorimetric assay for detecting hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) and glucose, which exhibited high stability, sensitivity, and accuracy in biological samples such as serum. Furthermore, by leveraging the reversible structural dynamics of Fc(COOH)<sub>2</sub>-PBA, we engineered a dual-mode colorimetric assay for visual quantitation of H<sub>2</sub>O<sub>2</sub> and glucose in complex samples, including cells, tissues, and cerebrospinal fluid. The distinct colorimetric response of this system demonstrates promising potential for point-of-care testing applications. Our findings provide mechanistic insights into the structure-activity relationships of nanozymes and will facilitate the development of application-targeted nanozymes for disease diagnostics.</p>","PeriodicalId":259,"journal":{"name":"Biosensors and Bioelectronics","volume":" ","pages":"117714"},"PeriodicalIF":10.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144493209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IF 3.3 2区 化学
Journal of Organic Chemistry Pub Date : 2025-07-25
Jingyu Li, Long Chen, Ziqi Dang, Wei Dong, Zixin Ye, Zhen Qin, Ming Li, Shuxia Wang, Xiulian Zhang* and Chuanzhou Tao*, 
{"title":"","authors":"Jingyu Li,&nbsp;Long Chen,&nbsp;Ziqi Dang,&nbsp;Wei Dong,&nbsp;Zixin Ye,&nbsp;Zhen Qin,&nbsp;Ming Li,&nbsp;Shuxia Wang,&nbsp;Xiulian Zhang* and Chuanzhou Tao*,&nbsp;","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":57,"journal":{"name":"Journal of Organic Chemistry","volume":"90 29","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":3.3,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acs.joc.5c00845","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144696333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IF 3.3 2区 化学
Journal of Organic Chemistry Pub Date : 2025-07-25
{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":57,"journal":{"name":"Journal of Organic Chemistry","volume":"90 29","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":3.3,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/jov090i029_1963685","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144696335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IF 3.3 2区 化学
Journal of Organic Chemistry Pub Date : 2025-07-25
Miho Yoshiki, Shiori Koyama, Hironao Kobayashi, Shotaro Mimura, Tomonari Ri, Hiromichi Nishiyama, Yusuke Sasano, Yoshiharu Iwabuchi, Junko Fujimoto, Aoi Kimishima, Masako Honsho, Hiromasa Yokoe, Kazutada Ikeuchi, Yukihiro Asami and Naoki Kanoh*, 
{"title":"","authors":"Miho Yoshiki,&nbsp;Shiori Koyama,&nbsp;Hironao Kobayashi,&nbsp;Shotaro Mimura,&nbsp;Tomonari Ri,&nbsp;Hiromichi Nishiyama,&nbsp;Yusuke Sasano,&nbsp;Yoshiharu Iwabuchi,&nbsp;Junko Fujimoto,&nbsp;Aoi Kimishima,&nbsp;Masako Honsho,&nbsp;Hiromasa Yokoe,&nbsp;Kazutada Ikeuchi,&nbsp;Yukihiro Asami and Naoki Kanoh*,&nbsp;","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":57,"journal":{"name":"Journal of Organic Chemistry","volume":"90 29","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":3.3,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acs.joc.5c00998","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144696336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IF 3.3 2区 化学
Journal of Organic Chemistry Pub Date : 2025-07-25
Lei Deng, Honghua Zuo, Hendrik F. T. Klare and Martin Oestreich*, 
{"title":"","authors":"Lei Deng,&nbsp;Honghua Zuo,&nbsp;Hendrik F. T. Klare and Martin Oestreich*,&nbsp;","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":57,"journal":{"name":"Journal of Organic Chemistry","volume":"90 29","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":3.3,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acs.joc.5c01473","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144696356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Norrish-Yang Cyclization of Imidazolidinone Derivatives in the Presence and Absence of Tetraalkylammonium Salts. 咪唑烷酮衍生物在四烷基铵盐存在和不存在条件下的Norrish-Yang环化反应。
IF 4.354 2区 化学
Journal of Organic Chemistry Pub Date : 2025-07-25 DOI: 10.1021/acs.joc.5c00981
Shinji Yamada,Kahoko Miyashita,Hanako Nakajima,Maho Iwata
{"title":"Norrish-Yang Cyclization of Imidazolidinone Derivatives in the Presence and Absence of Tetraalkylammonium Salts.","authors":"Shinji Yamada,Kahoko Miyashita,Hanako Nakajima,Maho Iwata","doi":"10.1021/acs.joc.5c00981","DOIUrl":"https://doi.org/10.1021/acs.joc.5c00981","url":null,"abstract":"Norrish-Yang cyclization reactions have attracted much attention in synthetic organic chemistry due to their ability to activate and functionalize inactive CH positions. In this study, we report that the diastereoselective course of the Norrish-Yang reaction of imidazolidinone derivatives is reversed by the addition of tetrabutylammonium salts (TBAX). 1H NMR experiments suggested that cation-π interactions between TBA+ and the substrate control the reactive conformation of this latter species. In the course of this study, we found that unexpected compounds with 6/7/5- and 6/6/5-fused tricyclic systems containing an aromatic ring were also formed in the presence and absence of TBAX, respectively. Furthermore, we report the formation of an unexpected fused tetracyclic compound, the framework structure of which resembles that of a tetraquinane, when a substrate with 2-benzoylethyl side chains on both nitrogen atoms of the imidazolidinones is used.","PeriodicalId":57,"journal":{"name":"Journal of Organic Chemistry","volume":"77 1","pages":""},"PeriodicalIF":4.354,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144701161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emergence of Compact Oligomers inside the Small-World Network of TDP-43 Condensates. TDP-43凝析油小世界网络中致密低聚物的出现
IF 6.475 2区 化学
The Journal of Physical Chemistry Letters Pub Date : 2025-07-25 DOI: 10.1021/acs.jpclett.5c01627
Huayuan Tang,Yunxiang Sun,Lei Wang,Pu Chun Ke,Feng Ding
{"title":"Emergence of Compact Oligomers inside the Small-World Network of TDP-43 Condensates.","authors":"Huayuan Tang,Yunxiang Sun,Lei Wang,Pu Chun Ke,Feng Ding","doi":"10.1021/acs.jpclett.5c01627","DOIUrl":"https://doi.org/10.1021/acs.jpclett.5c01627","url":null,"abstract":"Liquid-liquid phase separation (LLPS) of TDP-43 mediates the formation of pathological inclusions in various neurodegenerative diseases, with the condensate structures and related amyloid aggregation remaining elusive. Here, by developing a data-driven bottom-up coarse-grained model using discrete molecular dynamics simulations, we found proteins in the condensates of TDP-43 forming a dynamic network of fluctuating sizes. While dominated by peptides engaged with a small number of peptides connected by a low number of interpeptide contacts, the condensates also contained peptides with large numbers of connections, serving as hubs of a small-world network. Importantly, peptides in these high-contact states were intertwined to form oligomers that were stable for relatively long periods inside the weakly connected network. These oligomers were likely the aggregation intermediates toward nucleation of amyloid fibrils. Therefore, this transferable coarse-grained model may serve as a powerful tool for unraveling the inner workings of LLPS and amyloid aggregation.","PeriodicalId":62,"journal":{"name":"The Journal of Physical Chemistry Letters","volume":"9 1","pages":"7797-7806"},"PeriodicalIF":6.475,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144701178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Benzotriazoles and Benzothiazoles, Maternal and Neonatal Thyroid Hormones, and Childhood Growth: A Longitudinal Cohort Study. 苯并三唑和苯并噻唑,母亲和新生儿甲状腺激素和儿童生长:一项纵向队列研究。
IF 9.028 1区 环境科学与生态学
环境科学与技术 Pub Date : 2025-07-25 DOI: 10.1021/acs.est.5c03841
Ruixin Chen,Yanqiu Zhou,Yin Wang,Rongrong Cheng,Pei Li,Yuyan Wang,Yangqian Jiang,Jingyu Wang,Yuehao Fu,Baiwen Ni,Chenhui Yang,Wei Xia,Zongwei Cai,Hongxiu Liu,Shunqing Xu,Yuanyuan Li
{"title":"Benzotriazoles and Benzothiazoles, Maternal and Neonatal Thyroid Hormones, and Childhood Growth: A Longitudinal Cohort Study.","authors":"Ruixin Chen,Yanqiu Zhou,Yin Wang,Rongrong Cheng,Pei Li,Yuyan Wang,Yangqian Jiang,Jingyu Wang,Yuehao Fu,Baiwen Ni,Chenhui Yang,Wei Xia,Zongwei Cai,Hongxiu Liu,Shunqing Xu,Yuanyuan Li","doi":"10.1021/acs.est.5c03841","DOIUrl":"https://doi.org/10.1021/acs.est.5c03841","url":null,"abstract":"Prenatal exposure to benzotriazoles and benzothiazoles (BTs) has been associated with pregnancy complications, but their effects on childhood development remain unclear. We investigated these associations and examined the mediating role of maternal and neonatal thyroid hormones in a Chinese birth cohort consisting of 501 mother-child pairs. We found that exposure to 2-hydroxy-benzothiazole (2-OH-BTH) in early pregnancy was inversely associated with childhood body mass index (BMI) (β = -0.041, 95% CI: -0.077, -0.005). Both tolyl-triazole (TTR) (β = -1.35%, 95% CI: -2.45%, -0.24%) and 2-OH-BTH (β = -1.15%, 95% CI: -1.79%, -0.50%) were inversely associated with maternal free thyroxine (FT4) in early pregnancy, which mediated 23.53% of the inverse associations between 2-OH-BTH exposure and childhood BMI. Additionally, third-trimester exposure to 1-hydroxy-benzotriazole, xylyl-triazole, TTR, and 2-OH-BTH was positively linked to neonatal thyroid-stimulating hormone levels. These findings suggest that prenatal exposure to BTs, particularly 2-OH-BTH, may impair early childhood growth by disrupting thyroid hormone homeostasis. Our results add new epidemiological evidence to the growing concern about BTs and underscore the importance of considering thyroid disruption as a mechanistic link between environmental exposures and developmental outcomes. This highlights the need for greater public health attention and regulatory measures targeting these emerging contaminants.","PeriodicalId":36,"journal":{"name":"环境科学与技术","volume":"16 1","pages":""},"PeriodicalIF":9.028,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144701189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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