{"title":"Advances in computer vision-based structural health monitoring techniques for wind turbine blades","authors":"Shohreh Sheiati, Xiao Chen","doi":"10.1016/j.rser.2025.116078","DOIUrl":"10.1016/j.rser.2025.116078","url":null,"abstract":"<div><div>With the rapid growth of wind energy, larger wind turbines with longer blades have been developed to maximize energy production. However, the increased blade size has also led to higher repair and maintenance costs, which demands efficient and reliable structural health monitoring techniques for wind turbine blades. Computer vision techniques have emerged as promising tools to address the key topics in blade structural health monitoring, including damage detection, damage localization, damage classification, and damage quantification. Despite recent advancements in both traditional computer vision methods and advanced approaches like deep learning, a comprehensive evaluation of the most effective computer vision techniques for structural health monitoring of wind turbine blades remains absent. This includes consideration of task-specific conditions such as environmental variability, computational requirements, and characteristics of different blade damages. This paper analyzes the strengths and limitations of state-of-the-art computer vision techniques for structural health monitoring of wind turbine blades, as well as the imaging modalities applicable to capturing different blade damages. This study also identifies the existing research gaps and future research for advancing computer vision-based structural health monitoring of wind turbine blades.</div></div>","PeriodicalId":418,"journal":{"name":"Renewable and Sustainable Energy Reviews","volume":"224 ","pages":"Article 116078"},"PeriodicalIF":16.3,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144703289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Norrish-Yang Cyclization of Imidazolidinone Derivatives in the Presence and Absence of Tetraalkylammonium Salts.","authors":"Shinji Yamada,Kahoko Miyashita,Hanako Nakajima,Maho Iwata","doi":"10.1021/acs.joc.5c00981","DOIUrl":"https://doi.org/10.1021/acs.joc.5c00981","url":null,"abstract":"Norrish-Yang cyclization reactions have attracted much attention in synthetic organic chemistry due to their ability to activate and functionalize inactive CH positions. In this study, we report that the diastereoselective course of the Norrish-Yang reaction of imidazolidinone derivatives is reversed by the addition of tetrabutylammonium salts (TBAX). 1H NMR experiments suggested that cation-π interactions between TBA+ and the substrate control the reactive conformation of this latter species. In the course of this study, we found that unexpected compounds with 6/7/5- and 6/6/5-fused tricyclic systems containing an aromatic ring were also formed in the presence and absence of TBAX, respectively. Furthermore, we report the formation of an unexpected fused tetracyclic compound, the framework structure of which resembles that of a tetraquinane, when a substrate with 2-benzoylethyl side chains on both nitrogen atoms of the imidazolidinones is used.","PeriodicalId":57,"journal":{"name":"Journal of Organic Chemistry","volume":"77 1","pages":""},"PeriodicalIF":4.354,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144701161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Huayuan Tang,Yunxiang Sun,Lei Wang,Pu Chun Ke,Feng Ding
{"title":"Emergence of Compact Oligomers inside the Small-World Network of TDP-43 Condensates.","authors":"Huayuan Tang,Yunxiang Sun,Lei Wang,Pu Chun Ke,Feng Ding","doi":"10.1021/acs.jpclett.5c01627","DOIUrl":"https://doi.org/10.1021/acs.jpclett.5c01627","url":null,"abstract":"Liquid-liquid phase separation (LLPS) of TDP-43 mediates the formation of pathological inclusions in various neurodegenerative diseases, with the condensate structures and related amyloid aggregation remaining elusive. Here, by developing a data-driven bottom-up coarse-grained model using discrete molecular dynamics simulations, we found proteins in the condensates of TDP-43 forming a dynamic network of fluctuating sizes. While dominated by peptides engaged with a small number of peptides connected by a low number of interpeptide contacts, the condensates also contained peptides with large numbers of connections, serving as hubs of a small-world network. Importantly, peptides in these high-contact states were intertwined to form oligomers that were stable for relatively long periods inside the weakly connected network. These oligomers were likely the aggregation intermediates toward nucleation of amyloid fibrils. Therefore, this transferable coarse-grained model may serve as a powerful tool for unraveling the inner workings of LLPS and amyloid aggregation.","PeriodicalId":62,"journal":{"name":"The Journal of Physical Chemistry Letters","volume":"9 1","pages":"7797-7806"},"PeriodicalIF":6.475,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144701178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Benzotriazoles and Benzothiazoles, Maternal and Neonatal Thyroid Hormones, and Childhood Growth: A Longitudinal Cohort Study.","authors":"Ruixin Chen,Yanqiu Zhou,Yin Wang,Rongrong Cheng,Pei Li,Yuyan Wang,Yangqian Jiang,Jingyu Wang,Yuehao Fu,Baiwen Ni,Chenhui Yang,Wei Xia,Zongwei Cai,Hongxiu Liu,Shunqing Xu,Yuanyuan Li","doi":"10.1021/acs.est.5c03841","DOIUrl":"https://doi.org/10.1021/acs.est.5c03841","url":null,"abstract":"Prenatal exposure to benzotriazoles and benzothiazoles (BTs) has been associated with pregnancy complications, but their effects on childhood development remain unclear. We investigated these associations and examined the mediating role of maternal and neonatal thyroid hormones in a Chinese birth cohort consisting of 501 mother-child pairs. We found that exposure to 2-hydroxy-benzothiazole (2-OH-BTH) in early pregnancy was inversely associated with childhood body mass index (BMI) (β = -0.041, 95% CI: -0.077, -0.005). Both tolyl-triazole (TTR) (β = -1.35%, 95% CI: -2.45%, -0.24%) and 2-OH-BTH (β = -1.15%, 95% CI: -1.79%, -0.50%) were inversely associated with maternal free thyroxine (FT4) in early pregnancy, which mediated 23.53% of the inverse associations between 2-OH-BTH exposure and childhood BMI. Additionally, third-trimester exposure to 1-hydroxy-benzotriazole, xylyl-triazole, TTR, and 2-OH-BTH was positively linked to neonatal thyroid-stimulating hormone levels. These findings suggest that prenatal exposure to BTs, particularly 2-OH-BTH, may impair early childhood growth by disrupting thyroid hormone homeostasis. Our results add new epidemiological evidence to the growing concern about BTs and underscore the importance of considering thyroid disruption as a mechanistic link between environmental exposures and developmental outcomes. This highlights the need for greater public health attention and regulatory measures targeting these emerging contaminants.","PeriodicalId":36,"journal":{"name":"环境科学与技术","volume":"16 1","pages":""},"PeriodicalIF":9.028,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144701189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hydrogel microneedle based transdermal fluorescent patch for the on-site and non-invasive diagnosis of Alzheimer's disease","authors":"Yingchun Zuo , Shiyu He , Wenmeng Zhang , Yanqing Wu , Huijun Qiao , Xinguang Zhou , Yanyan Yu","doi":"10.1016/j.bios.2025.117823","DOIUrl":"10.1016/j.bios.2025.117823","url":null,"abstract":"<div><div>Detection of biomarkers in interstitial fluid (ISF) by microneedles (MNs) has received extensive attentions as a non-invasive biosensing strategy. However, fewer work has focused on the long non-coding RNAs (lncRNAs) sensing, which are most likely present in ISF and engage in the occurrence and development of Alzheimer's disease (AD). In this work, taking adenocarcinoma transcript 1 (MALAT1) as the representative of lncRNAs, which is abnormally down-regulated in AD patients, a robust hydrogel MN array - based fluorescent patch was developed for MALAT1 by integrating a methacrylated gelatin (GelMA) hydrogel MN as the extraction tool with a strand displacement reaction (SDR) mediated fluorescent probe. Specifically, the MNs were prepared by the simple and feasible photo-crosslinking of GelMA, which displayed satisfactory swelling capability for extracting ISF and mechanical strength to penetrate the skin's cuticle layer. Subsequently, a triplex SDR amplification probe was constructed for MALAT1 sensing. By mixing with the prepolymer solution, the MNs patch loaded with the fluorescent probe was fabricated, which demonstrated excellent sensing performances in both PBS and agarose simulated skin, with lower limits of quantification (LLOQ) of 7.62 and 13.24 nM, respectively. The developed MN patch was proved highly suitable for distinguishing the down-regulated MALAT1 expressions in ISF of AD mice. This work represented the first example to correlate the changes in the levels of MALAT1 in ISF with AD pathology, providing a practical tool for the early non - invasive diagnosis of AD.</div></div>","PeriodicalId":259,"journal":{"name":"Biosensors and Bioelectronics","volume":"288 ","pages":"Article 117823"},"PeriodicalIF":10.7,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144702248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Radhakrishnam R. Ruddarraju, Yuya Komatani, Yasuaki Tokodai and Satoshi Ichikawa*,
{"title":"","authors":"Radhakrishnam R. Ruddarraju, Yuya Komatani, Yasuaki Tokodai and Satoshi Ichikawa*, ","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":57,"journal":{"name":"Journal of Organic Chemistry","volume":"90 29","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":3.3,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acs.joc.5c01110","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144696360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hikaru Ishikura, Juan J Rojas, Callum S Begg, Chulho Choi, James A Bull
{"title":"Synthesis of <i>gem</i>-Difluorocyclobutanes: Organolanthanum Enabled Synthesis and Divergent Catalytic Functionalization of <i>gem</i>-Difluorocyclobutanols.","authors":"Hikaru Ishikura, Juan J Rojas, Callum S Begg, Chulho Choi, James A Bull","doi":"10.1021/acs.joc.5c01175","DOIUrl":"10.1021/acs.joc.5c01175","url":null,"abstract":"<p><p>Fluorinated cycloalkyl motifs continue to receive intense interest in medicinal chemistry due to their potential to modulate physicochemical properties. In recent years, this interest has extended to <i>gem</i>-difluorocyclobutanes as small, polar, yet lipophilic moieties. However, strategies to access <i>gem</i>-difluorocyclobutanes remain limited, presenting opportunities for the development of new synthetic methods. Here, we report the synthesis and divergent functionalization of <i>gem</i>-difluorocyclobutanols to generate a diverse range of 1,1-disubstituted-3,3-difluorocyclobutanes. The use of organolanthanum reagents is crucial to achieve the addition of carbon nucleophiles to commercially available difluorocyclobutanone to avoid the undesired elimination of HF by controlling nucleophile basicity. The generated difluorocyclobutanols enable functionalization through carbocation and radical intermediates, providing diverse 1,1-disubstituted difluorocyclobutanes and expediting access to new design options for medicinal or materials chemistry.</p>","PeriodicalId":57,"journal":{"name":"Journal of Organic Chemistry","volume":" ","pages":"10425-10433"},"PeriodicalIF":3.3,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144606791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yaxuan Wang , Shilong Guo , Yue Cui , Liang Deng , Lei Zhao , Junfu Li , Zhenbo Wang
{"title":"A comprehensive review of machine learning-based state of health estimation for lithium-ion batteries: data, features, algorithms, and future challenges","authors":"Yaxuan Wang , Shilong Guo , Yue Cui , Liang Deng , Lei Zhao , Junfu Li , Zhenbo Wang","doi":"10.1016/j.rser.2025.116125","DOIUrl":"10.1016/j.rser.2025.116125","url":null,"abstract":"<div><div>Lithium-ion batteries are widely used in electric vehicles and energy storage systems, where reliable state of health (SOH) estimation is critical to ensure operational safety and lifecycle management. In recent years, machine learning (ML) has emerged as a powerful data-driven tool for battery SOH estimation due to its capability in learning complex degradation patterns from data. This review systematically examines the full ML-based SOH estimation workflow, beginning with an overview of measured, public, and synthetic datasets and common preprocessing techniques. The review then emphasizes feature engineering, analyzing the extraction of health indicators from voltage, current, temperature, incremental capacity (IC) curves, and advanced sensor data, as well as feature selection methods that improve model efficiency and robustness. On this basis, various ML algorithms are evaluated in terms of accuracy, generalization, practical deployment, and other key attributes. Finally, the review discusses ongoing challenges such as data scarcity, domain transferability, and physical consistency, and highlights future directions including physics-informed learning and hybrid data–model fusion. This work offers a comprehensive reference and forward-looking insight into the development of intelligent, reliable, and interpretable battery health estimation systems.</div></div>","PeriodicalId":418,"journal":{"name":"Renewable and Sustainable Energy Reviews","volume":"224 ","pages":"Article 116125"},"PeriodicalIF":16.3,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144703291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}