Trends in Analytical Chemistry最新文献

Determination and assessment of contamination of toxic chemical elements in soils – Review 土壤中有毒化学元素污染的测定与评估 - 综述

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2024-11-15 DOI: 10.1016/j.trac.2024.118055

Sergio L.C. Ferreira , Leonardo S.G. Teixeira , William Q. Ferreira , Saulo V.A. Dantas , Adriana S. Lima , Maria G.A. Korn , Francisco A.S. Cunha , Victor Cerda , Walter N.L. dos Santos , Jucelino B. da Silva Junior , Olivia M.C. Oliveira

{"title":"Determination and assessment of contamination of toxic chemical elements in soils – Review","authors":"Sergio L.C. Ferreira , Leonardo S.G. Teixeira , William Q. Ferreira , Saulo V.A. Dantas , Adriana S. Lima , Maria G.A. Korn , Francisco A.S. Cunha , Victor Cerda , Walter N.L. dos Santos , Jucelino B. da Silva Junior , Olivia M.C. Oliveira","doi":"10.1016/j.trac.2024.118055","DOIUrl":"10.1016/j.trac.2024.118055","url":null,"abstract":"<div><div>This work reviews the main topics in determining and evaluating the contamination of the toxic chemical elements antimony, arsenic, cadmium, lead, and mercury in soils. Initially, the sampling and storage steps are discussed. Next, the advantages and limitations of drying methods using oven heating, freeze-drying, air drying, and infrared radiation are presented. Subsequently, the importance of particle size in soil analysis is addressed. In addition, sample preparation procedures involving microwave-assisted radiation and the acids and their mixtures used for digestion of soil matrices are commented. Subsequently, the spectrometric analytical methods used to quantify chemical elements, such as inductively coupled plasma optical emission spectrometry (ICP OES), inductively coupled plasma mass spectrometry (ICP-MS), atomic fluorescence spectrometry (AFS), atomic absorption spectrometry with electrothermal atomization (ET AAS) and the direct mercury analyzer (DMA) are compared. Finally, the single and integrated indices used to evaluate the contamination of soils with toxic chemical elements in are briefly reported.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"181 ","pages":"Article 118055"},"PeriodicalIF":11.8,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142658101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Recent advances in X-ray grating-based dark-field imaging 基于 X 射线光栅的暗场成像技术的最新进展

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2024-11-13 DOI: 10.1016/j.trac.2024.118052

Zhili Wang

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Integrated breath analysis technologies: Current advances and future prospects 综合呼气分析技术：当前进展与未来展望

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2024-11-12 DOI: 10.1016/j.trac.2024.118048

Oluwatoyin Emmanuel Aina, Nadia Zine, Guy Raffin, Nicole Jaffrezic-Renault, Abdelhamid Elaissari, Abdelhamid Errachid

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Advancements in CRISPR-diagnostic techniques for rapid on-site monitoring of environmental virus 用于现场快速监测环境病毒的 CRISPR 诊断技术取得进展

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2024-11-08 DOI: 10.1016/j.trac.2024.118046

Zhaojia Deng , Wenjing Liao , Liangyun Bu , Jinhua Li , Juan Li , Lingfeng Wang , Aijiao Yuan , Wenjing Xie , Yawei Wang , Hanyong Peng

{"title":"Advancements in CRISPR-diagnostic techniques for rapid on-site monitoring of environmental virus","authors":"Zhaojia Deng , Wenjing Liao , Liangyun Bu , Jinhua Li , Juan Li , Lingfeng Wang , Aijiao Yuan , Wenjing Xie , Yawei Wang , Hanyong Peng","doi":"10.1016/j.trac.2024.118046","DOIUrl":"10.1016/j.trac.2024.118046","url":null,"abstract":"<div><div>Highly sensitive and rapid environmental surveillance is crucial due to the significant role of various environmental media in transmitting multiple viruses. Specifically, when examining the case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), such surveillance not only provides early warning information for epidemic prevention and control but also enhances our understanding of transmission pathways from an environmental perspective. To achieve effective surveillance, rapid screening techniques are essential to detect and prevent the spread of SARS-CoV-2 in the environment. The integration of isothermal amplification with the CRISPR-Cas system, coupled with advancements in amplification-free technologies, has revolutionized the direct visual detection of environmental viruses at testing sites. However, currently, this emerging technology is mainly utilized in clinical diagnosis due to interdisciplinary barriers and the complexities associated with environmental samples. This review aims to bridge the gap by introducing CRISPR-based molecular diagnosis techniques into practical environmental screening demands. It provides a comprehensive analysis of the environmental surveillance process and explores the development of timely detection technology. Furthermore, the review emphasizes the importance of portable devices, data interpretation, and sharing for real-time and on-site surveillance of environmental viruses, thereby improving preparedness for future potential pandemics.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"181 ","pages":"Article 118046"},"PeriodicalIF":11.8,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142657613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Recent advancements in polyaniline-based biosensors for diagnosis of cancers: A comprehensive review 用于诊断癌症的聚苯胺基生物传感器的最新进展：综述

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2024-11-08 DOI: 10.1016/j.trac.2024.118040

Mojtaba Hosseine , Ali Bakhshi , Seyed Morteza Naghib , Navid Rabiee

{"title":"Recent advancements in polyaniline-based biosensors for diagnosis of cancers: A comprehensive review","authors":"Mojtaba Hosseine , Ali Bakhshi , Seyed Morteza Naghib , Navid Rabiee","doi":"10.1016/j.trac.2024.118040","DOIUrl":"10.1016/j.trac.2024.118040","url":null,"abstract":"<div><div>Recent advances in biosensor and bioelectronics technologies have revolutionized cancer diagnosis, providing more accessible, sensitive, and specific methods for early detection. This review focuses on polyaniline (PANI)-based biosensors, which demonstrate significant potential in detecting cancer biomarkers due to their tunable properties, cost-effectiveness, and ease of synthesis. Various PANI synthesis techniques, including chemical, electrochemical, enzyme-catalyzed, vapor-phase, and template-assisted polymerization, are examined, along with the development of multidimensional PANI nanostructures to enhance biosensor performance. Advanced 3D printing techniques have enabled the precise fabrication of PANI-based devices, such as flexible sensors, high-performance supercapacitors, and electroactive scaffolds, showcasing PANI's versatility and potential in biomedical and biosensor applications. The application of PANI-based biosensors in detecting lung, liver, breast, and prostate cancers is discussed, highlighting the detection principles, limits, and specificity for each cancer type. Furthermore, the role of PANI in signal amplification through nanocomposite (NC) integration, which improves diagnostic accuracy, is explored. This comprehensive review also addresses the current challenges and future opportunities for advancements in PANI-based biosensor technology, emphasizing its critical importance in the next generation of cancer diagnostics. By overcoming the limitations of conventional diagnostic methods, these biosensors are positioned to play a pivotal role in improving early cancer detection and patient outcomes.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"181 ","pages":"Article 118040"},"PeriodicalIF":11.8,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142658104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Evaluating excitation-emission matrix for characterization of dissolved organic matter in natural and engineered water systems: Unlocking submerged secrets 评估自然和工程水系统中溶解有机物特征的激发-发射矩阵：揭开水下的秘密

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2024-11-08 DOI: 10.1016/j.trac.2024.118045

Bo Gong , Wei Chen , Chen Qian , Han-Qing Yu

{"title":"Evaluating excitation-emission matrix for characterization of dissolved organic matter in natural and engineered water systems: Unlocking submerged secrets","authors":"Bo Gong , Wei Chen , Chen Qian , Han-Qing Yu","doi":"10.1016/j.trac.2024.118045","DOIUrl":"10.1016/j.trac.2024.118045","url":null,"abstract":"<div><div>Dissolved organic matter (DOM) is ubiquitous in waters and plays a fundamental role. The examination of DOM properties and their environmental effects, including intrinsic biogeochemical processes and the impact of DOM on the transformation and fate of other contaminants, is of paramount significance. Among the techniques available for DOM characterization, the fluorescent excitation-emission matrix (EEM) stands out as one of the most powerful methods, due to its speed, high sensitivity, and wealth of molecular information provided. This review encapsulates the principles of EEM-based methodologies for DOM interpretation, then critically summarizes DOM characterization in natural waters, and wastewater, as well as the water and wastewater treatment processes. Various scientific issues related to DOM, such as its physicochemical and biochemical properties, spatial and temporal distribution, transformation, removal, and environmental implications, can be discerned using EEM. Finally, the limitations and challenges, as well as the potential advancements and perspectives on EEM collection and analytical tools are discussed, broadening the application scope and utilizing theoretical simulation for mechanism investigation. This review serves as a beneficial guide to selecting suitable EEM-related strategies, facilitating an in-depth understanding and forecasting of the environmental behaviors of DOM in both natural and engineered water systems.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"181 ","pages":"Article 118045"},"PeriodicalIF":11.8,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142657614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Compound-specific isotope analysis of amino acids for aquatic systems – Problems, challenges, solutions: A review 水生系统氨基酸的特定化合物同位素分析--问题、挑战和解决方案：综述

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2024-11-07 DOI: 10.1016/j.trac.2024.118038

Shaista Khaliq , Maik A. Jochmann , Tobias Hesse , Milen Nachev , Bernd Sures , Philip M. Riekenberg , Marcel T.J. van der Meer , Torsten C. Schmidt

{"title":"Compound-specific isotope analysis of amino acids for aquatic systems – Problems, challenges, solutions: A review","authors":"Shaista Khaliq , Maik A. Jochmann , Tobias Hesse , Milen Nachev , Bernd Sures , Philip M. Riekenberg , Marcel T.J. van der Meer , Torsten C. Schmidt","doi":"10.1016/j.trac.2024.118038","DOIUrl":"10.1016/j.trac.2024.118038","url":null,"abstract":"<div><div>Compound-specific isotope analysis of individual amino acids (AAs) is a promising method for characterizing resource flow and transformation in aquatic systems, encompassing microbial domains to macroscopic consumers. This review delves into two key areas of research concerning AAs in aquatic ecosystems. Firstly, carbon isotope analysis is employed to explore carbon sources assimilated for AAs synthesis, and secondly, nitrogen isotope analysis is used to clarify ecosystem baselines and trophic dynamics of organisms. Surprisingly, literature provides limited discussions on the limitations or critical challenges faced during AAs isotope analysis over the past decade. To address this gap, this review focuses on challenges encountered in method development, sample preparation, and technical aspects, including instrumental design, and δ<sup>13</sup>C and δ<sup>15</sup>N analysis of AAs. Recommendations are provided to increase the accuracy and reliability. The review also highlights the significance of comprehensive understanding and detailed methodology to address challenges during AA isotope analysis in aquatic systems.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"181 ","pages":"Article 118038"},"PeriodicalIF":11.8,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142658103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Microextraction by packed sorbents (MEPS): Fundamental principles and nanomaterial-based adsorbents 填料吸附剂微萃取（MEPS）：基本原理和基于纳米材料的吸附剂

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2024-11-07 DOI: 10.1016/j.trac.2024.118043

Ali Firoozichahak , Danial Soleymani-ghoozhdi , Saber Alizadeh , Razzagh Rahimpoor

{"title":"Microextraction by packed sorbents (MEPS): Fundamental principles and nanomaterial-based adsorbents","authors":"Ali Firoozichahak , Danial Soleymani-ghoozhdi , Saber Alizadeh , Razzagh Rahimpoor","doi":"10.1016/j.trac.2024.118043","DOIUrl":"10.1016/j.trac.2024.118043","url":null,"abstract":"<div><div>Sample preparation is a crucial aspect of analytical methods, particularly when dealing with complex matrices and/or low concentrations of analytes. Recent advancements in analytical methods have focused on minimizing sample preparation devices, evolving towards extraction techniques that utilize solvent-free or green solvents, or minimal amounts of solvents. Microextraction by Packed Sorbent (MEPS) is a miniaturized version of the conventional Solid-phase extraction (SPE) technique. The MEPS has been recognized as a modern technique in sample preparation due to the minimal use of solid adsorbent, organic solvent, and liquid sample. This innovative technique allows for the recovery of the adsorbents and contributes to sustainability. Furthermore, MEPS can be seamlessly integrated with chromatographic systems in an automated manner to enhance both efficiency and reproducibility. This review tries to have comprehensive insight into the various MEPS technique, advancements, and emerging trends with emphasis on the wide range of employed nanomaterials as adsorbents.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"181 ","pages":"Article 118043"},"PeriodicalIF":11.8,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142657611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Metabolite Annotation through Stable Isotope Labeling 通过稳定同位素标记进行代谢物注释

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2024-11-07 DOI: 10.1016/j.trac.2024.118037

Yonghui Dong , Liron Feldberg , Asaph Aharoni , Uwe Heinig

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Recent advances in bioactivity-guided drug screening strategies for pre-clinical and clinical drug discovery 用于临床前和临床药物发现的生物活性指导药物筛选策略的最新进展

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2024-11-05 DOI: 10.1016/j.trac.2024.118042

Simin Chen , Chenxiao Shen , Wanyu Li , Yu Fan , Dong-Hua Yang , Yitao Wang , Ruibing Feng , Guodong Li , Zhangfeng Zhong

{"title":"Recent advances in bioactivity-guided drug screening strategies for pre-clinical and clinical drug discovery","authors":"Simin Chen , Chenxiao Shen , Wanyu Li , Yu Fan , Dong-Hua Yang , Yitao Wang , Ruibing Feng , Guodong Li , Zhangfeng Zhong","doi":"10.1016/j.trac.2024.118042","DOIUrl":"10.1016/j.trac.2024.118042","url":null,"abstract":"<div><div>Over the past two decades, bioactivity-guided drug screening has become a pivotal approach in drug discovery, which could identify potential drug candidates with desirable therapeutic effects against specific disease phenotypes or targets. This strategy has led to the discovery of many clinical medications such as natural products, peptides, and antibody drugs, and become a mainstream method. Herein, we first systematically summarize the principles and applications of recent bioactivity-guided drug screening strategies through technological advances in <em>in silico</em> screening, cell model systems, organoid model systems, and animal model systems. We then provide an overview on the representative active compounds, pre-clinical drugs, and marketed drugs, and discuss the present challenges and future directions of bioactivity-guided drug screening methods for clinical drug development. Based on the research advancements, it is anticipated that more disease-relevant screening models and efficient methods can be developed to identify drugs with ideal therapeutic effects and favorable pharmacological properties.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"181 ","pages":"Article 118042"},"PeriodicalIF":11.8,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142657612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0