Trends in Analytical Chemistry最新文献

Technological innovations and applications of human olfaction analysis

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2024-11-26 DOI: 10.1016/j.trac.2024.118065

Yingjie Fu , Hui Xi , Dingzhong Wang , Baojiang He , Mengke Zheng , Ying Zhou , Ke Qin , Peng Li , Shihao Sun , Chao Lu

{"title":"Technological innovations and applications of human olfaction analysis","authors":"Yingjie Fu , Hui Xi , Dingzhong Wang , Baojiang He , Mengke Zheng , Ying Zhou , Ke Qin , Peng Li , Shihao Sun , Chao Lu","doi":"10.1016/j.trac.2024.118065","DOIUrl":"10.1016/j.trac.2024.118065","url":null,"abstract":"<div><div>Olfaction appeared much early than other senses for avoiding danger, seeking food and communication. Olfactory analysis is the key point in some industrial production processes and unique technological fields. Human olfaction plays an important role in real-time detection, olfactory assessment, threshold determination <em>etc</em>. Although, the demands for multiple objective analytical methods and precise quantitative analysis could boost the development of sensor-based instrumental olfaction, the research of human olfactory detection is the source and foundation of the artificial olfaction and electronic nose. This review summarizes the analytical applications of human olfaction and also presents the promising techniques for olfactory analysis. In addition, the combination of olfaction and analytical instruments is systemically discussed. Finally, the bionic sensors based on human olfaction are also reviewed in this work. With better understanding of analytical techniques of human olfaction, new methods of olfactory analysis could be discovered, enlightening the methodology of sensory analysis and the development of artificial olfaction.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"182 ","pages":"Article 118065"},"PeriodicalIF":11.8,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142746956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent trends in biosensors for leukemia diagnosis: A critical overview of electrochemical and optical approaches for clinical applicability 白血病诊断生物传感器的最新发展趋势：临床应用的电化学和光学方法综述

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2024-11-23 DOI: 10.1016/j.trac.2024.118063

Léony S. Oliveira , Cesar A.S. Andrade , Maria D.L. Oliveira , Nadia Zine , Abdelhamid Elaissari , Abdelhamid Errachid

{"title":"Recent trends in biosensors for leukemia diagnosis: A critical overview of electrochemical and optical approaches for clinical applicability","authors":"Léony S. Oliveira , Cesar A.S. Andrade , Maria D.L. Oliveira , Nadia Zine , Abdelhamid Elaissari , Abdelhamid Errachid","doi":"10.1016/j.trac.2024.118063","DOIUrl":"10.1016/j.trac.2024.118063","url":null,"abstract":"<div><div>Leukemia is a hematopoietic cancer with heterogeneous manifestations. For the initial diagnosis and risk stratification of patients, it is necessary to perform several tests together to delineate the prognosis and appropriate therapy. Initial tests involve the evaluation and detection of leukemic cells with complete blood count and flow cytometry with immunophenotyping. However, for decisive therapy classification, tests such as karyotyping, fluorescent <em>in situ</em> hybridization, and RT-PCR (transcriptase reaction combined with polymerase chain reaction) are indispensable. In view of this, various biosensors have been developed with the aim of addressing some of these limitations. This is because these devices are designed for low-cost, simple, and quickly interpretable detection with accuracy. Thus, this review discusses different strategies, techniques, and tools used in leukemia biosensors as well as the main challenges for the real applicability of bio-devices in diagnostic routines. In this regard, biosensors applied to leukemia have been subdivided into the detection of cells and oncogenes. He electrochemical and optical techniques used as transduction methods are discussed, along with nanostructuring, biomarkers, challenges, and perspectives of these tools. Additionally, general biomarkers of interest and innovative strategies involving the combination of different biomolecules are also discussed. Some challenges encountered include the application of biosensors in miniaturized systems compatible with lab-on-chip technologies, as well as devices capable of addressing the complexity of markers in relation to the molecular heterogeneity present in leukemia cases.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"182 ","pages":"Article 118063"},"PeriodicalIF":11.8,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142706217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mind your Ps and Qs – Caveats in metabolomics data analysis

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2024-11-23 DOI: 10.1016/j.trac.2024.118064

Yun Xu, Royston Goodacre

引用次数: 0

CRISPR diagnostics for WHO high-priority sexually transmitted infections 针对世卫组织高度优先性传播感染的 CRISPR 诊断技术

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2024-11-21 DOI: 10.1016/j.trac.2024.118054

Ijaz Gul , Muhammad Akmal Raheem , Md. Reyad-ul-Ferdous , Lijin Lian , Asad Mustafa Karim , Md Belal Bin Heyat , Dongmei Yu

{"title":"CRISPR diagnostics for WHO high-priority sexually transmitted infections","authors":"Ijaz Gul , Muhammad Akmal Raheem , Md. Reyad-ul-Ferdous , Lijin Lian , Asad Mustafa Karim , Md Belal Bin Heyat , Dongmei Yu","doi":"10.1016/j.trac.2024.118054","DOIUrl":"10.1016/j.trac.2024.118054","url":null,"abstract":"<div><div>Sexually transmitted infections (STIs) pose a global health threat. Most of these infections are curable if detected in a timely and accurate manner. In 2022, the World Health Organization (WHO) initiated a programme aimed at identifying key research areas and addressing the needs for controlling the unabated STIs. Among the 40 priority research needs identified, the development of detection methods that meet WHO's ASSURED criteria (accurate, sensitive, specific, user-friendly, rapid, equipment-free, and deliverable to end user) remained one of the top priorities, particularly for syphilis, chlamydia, and gonorrhea. The existing detection methods for these STIs do not fully meet the ASSURED criteria. CRISPR technology has garnered substantial research attention as a promising diagnostic tool for both infectious and non-infectious diseases. Given its importance in diagnostics, this review discusses the applications of CRISPR/Cas systems for detecting WHO high-priority STIs. We provide an account of CRISPR-based diagnostics for syphilis, chlamydia, and gonorrhea, highlight existing research gaps, and propose solutions that can contribute to WHO's 2030 Sustainable Development Goals (SDGs) for the healthcare sector.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"182 ","pages":"Article 118054"},"PeriodicalIF":11.8,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142706210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Toxicity mechanisms and alleviation strategies of micro/nanoplastics to animals: A review 微/纳米塑料对动物的毒性机制和缓解策略：综述

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2024-11-20 DOI: 10.1016/j.trac.2024.118061

Hongping Liao , Jun Liu , Dandan Gao , Guanglong Chen , Chunmiao Kong , Xiaohong Huang , Jun Wang

引用次数: 0

Sampling, extraction, and analysis of micro- and nano-plastics in environmental and biological compartments: A review

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2024-11-20 DOI: 10.1016/j.trac.2024.118056

Yiping Luo , Ruiqi Hu , Ye Zheng , Ling Ding , Xinran Qiu , Jiansheng Yang , Xujun Liang , Xuetao Guo

引用次数: 0

CRISPR-Cas-based colorimetric strategies for nucleic acids detection 基于 CRISPR-Cas 的核酸比色检测策略

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2024-11-20 DOI: 10.1016/j.trac.2024.118058

Yujin Yang , Xingyu Li , Xiaobo Wang, Zongji Wang, Shaohua Gong

{"title":"CRISPR-Cas-based colorimetric strategies for nucleic acids detection","authors":"Yujin Yang , Xingyu Li , Xiaobo Wang, Zongji Wang, Shaohua Gong","doi":"10.1016/j.trac.2024.118058","DOIUrl":"10.1016/j.trac.2024.118058","url":null,"abstract":"<div><div>Accurate and facile detection of nucleic acids is significant for diagnosis and prognosis of diseases. Compared with traditional methods, CRISPR-based diagnosis shows high sensitivity and specificity, hopefully becoming the next-generation molecular diagnosis approach. Various signal output modes have been integrated with CRISPR-Cas to achieve ultrasensitive detection of nucleic acid biomarkers. Among these signal modes, colorimetric signal attracts great attention due to its simplicity, which will contribute to the point-of-care testing of nucleic acid biomarkers. Therefore, different CRISPR-based colorimetric strategies have been designed, aiming to realize facile and ultrasensitive nucleic acid biomarkers detection. In this review, the working mechanism of four CRISPR-Cas systems is first introduced, followed by summarizing the research progress of CRISPR-Cas-based colorimetric strategies, including UV/blue light-based colorimetry, lateral flow strip-based colorimetry, AuNPs-based colorimetry in solution and enzyme-based colorimetry. Furthermore, the challenges and perspectives in this field are discussed to promote the development of CRISPR-Cas-based colorimetry in practical application.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"182 ","pages":"Article 118058"},"PeriodicalIF":11.8,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142706212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of tire wear-derived toxic organic substances and associated toxicological implications by mass spectrometry: Recent advances 利用质谱法分析轮胎磨损产生的有毒有机物质及其相关毒理学影响：最新进展

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2024-11-18 DOI: 10.1016/j.trac.2024.118059

Congcong Pei , Shijiao Hou , Zifang Peng , Xu Zhang , Dan Yin , Wenfen Zhang , Yanhao Zhang , Zongwei Cai , Shusheng Zhang

{"title":"Analysis of tire wear-derived toxic organic substances and associated toxicological implications by mass spectrometry: Recent advances","authors":"Congcong Pei , Shijiao Hou , Zifang Peng , Xu Zhang , Dan Yin , Wenfen Zhang , Yanhao Zhang , Zongwei Cai , Shusheng Zhang","doi":"10.1016/j.trac.2024.118059","DOIUrl":"10.1016/j.trac.2024.118059","url":null,"abstract":"<div><div>Tire wear-derived toxic organic substances (TWTOSs), as broadly distributed and poisonous contaminants, have threatened the safety of the environment, food, and organisms. Accurate, sensitive, and rapid detection of TWTOSs is essential for understanding their occurrence, environmental fate, and biotoxicities. Mass spectrometry (MS) has been increasingly employed for identification, quantification, and toxicity tracking of emerging pollutants in terms of high sensitivity/throughput and easy operation. Herein, we reviewed the recent advances of MS technology for detecting TWTOSs (e.g., cyclic amines and benzotriazoles/benzothiazoles) in the ecosystem and food/biological samples, and assessing the toxicological implications of TWTOSs on the organism. A comprehensive update on the MS-based detection of TWTOSs and the exposure risks’ evaluation will be provided in this review, highlighting the necessity of innovation of analytical technology for environmental and public health safety.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"182 ","pages":"Article 118059"},"PeriodicalIF":11.8,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142706214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spatial distribution and stability of Gd0.6Eu0.4VO4 nanoparticles injected in mouse ear pinnae 注入小鼠耳廓的 Gd0.6Eu0.4VO4 纳米粒子的空间分布和稳定性

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2024-11-16 DOI: 10.1016/j.trac.2024.118049

Eleni Proiou , Fani Pinakidou , Eleni C. Paloura , Nicolas Pétri , Thierry Gacoin , Corinne Laplace-Builhé , Götz Schuck , Antigoni Alexandrou , Maria Katsikini

{"title":"Spatial distribution and stability of Gd0.6Eu0.4VO4 nanoparticles injected in mouse ear pinnae","authors":"Eleni Proiou , Fani Pinakidou , Eleni C. Paloura , Nicolas Pétri , Thierry Gacoin , Corinne Laplace-Builhé , Götz Schuck , Antigoni Alexandrou , Maria Katsikini","doi":"10.1016/j.trac.2024.118049","DOIUrl":"10.1016/j.trac.2024.118049","url":null,"abstract":"<div><div>X-Ray Fluorescence (XRF) mapping is employed for the study of the spatial distribution of GdVO<sub>4</sub>:Eu nanoparticles (NPs) after their injection into mouse ear pinnae. The injected NP colloids were detectable in a concentration range from 5 to 30 mM in vanadate ions (90–530 nM in NP concentrations). The distribution maps were recorded separately for Gd, Eu, and V and reveal that the three elements are collocalized, indicating the NP stability after the injection. The distribution pattern of the NPs is not homogeneous; they follow bifurcated paths of easy flow demonstrating the complexity of the tissue-colloid interactions. The V–K, Gd-L<sub>3</sub> and Eu-L<sub>3</sub>-edge X-ray Absorption Fine Structure (XAFS) spectra of the NPs recorded prior to and after their injection confirm that the integrity of the nanoparticles is preserved after injection. This combined XRF/XAFS analysis paves the way for studies on the long-term fate of injected Gd-containing NPs in tissues.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"182 ","pages":"Article 118049"},"PeriodicalIF":11.8,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142720427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent developments and applications of artificial intelligence in solid/liquid extraction studies 人工智能在固/液萃取研究中的最新发展和应用

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2024-11-16 DOI: 10.1016/j.trac.2024.118057

Qamar Salamat , Zinar Pinar Gumus , Mustafa Soylak

引用次数: 0