Trends in Analytical Chemistry最新文献_第2页

Advanced deep learning algorithms in food quality and authenticity 先进的深度学习算法在食品质量和真实性

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2025-07-16 DOI: 10.1016/j.trac.2025.118374

Che Shen, Qi Jin, Ganghua Zhou, Ran Wang, Zhenwei Wang, Di Liu, Kezhou Cai, Baocai Xu

{"title":"Advanced deep learning algorithms in food quality and authenticity","authors":"Che Shen, Qi Jin, Ganghua Zhou, Ran Wang, Zhenwei Wang, Di Liu, Kezhou Cai, Baocai Xu","doi":"10.1016/j.trac.2025.118374","DOIUrl":"10.1016/j.trac.2025.118374","url":null,"abstract":"<div><div>Ensuring food quality and authenticity is critical to the food industry and consumers. With the advancements in Industry 4.0 and Artificial Intelligence (AI) technologies, deep learning (DL) offers unparalleled opportunities to extract information and make decisions on complex or large datasets. However, conventional convolutional neural networks (CNN) and recurrent neural networks (RNN) have limitations. The development of advanced DL algorithms can accommodate the growing demand for complex tasks and herald revolutionary breakthroughs in the field of food quality and authenticity identification, which will continue to be driven by the ongoing development of advanced DL. This review provides a comprehensive overview of various advanced DL algorithms for food quality identification and food authenticity analysis, including advanced variants of CNN, lightweight DL, sequential neural networks, graph neural networks (GNN), deep generative models (DGM), and target detection algorithms. It also surveys recent applications of advanced DL algorithms for Food quality inspection and authenticity analysis. This review discusses the challenges associated with advanced DL and the future trends, offering new insights into the development of advanced DL algorithms in food quality and authenticity. Challenges such as overfitting, scalability, interpretability, accessibility, data privacy, algorithmic bias, and the creation of large databases must be addressed in the application of advanced DL algorithms to drive their further iterations.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"191 ","pages":"Article 118374"},"PeriodicalIF":11.8,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144672644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

From extraction to detection: An analytical journey of plastic additives and their migrations 从提取到检测：塑料添加剂及其迁移的分析之旅

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2025-07-16 DOI: 10.1016/j.trac.2025.118373

Benjamin Caux , Clément De Saint Jores , Ramy Abou-Naccoul , Caroline West

{"title":"From extraction to detection: An analytical journey of plastic additives and their migrations","authors":"Benjamin Caux , Clément De Saint Jores , Ramy Abou-Naccoul , Caroline West","doi":"10.1016/j.trac.2025.118373","DOIUrl":"10.1016/j.trac.2025.118373","url":null,"abstract":"<div><div>Plastic materials, which are massively produced for a large variety of applications, require small organic molecules called additives to improve their physico-chemical properties. Plastic additives set health and environment issues, because they can migrate from the plastic material to contact matrices, which is a significant concern for food packaging, medical devices, toys, environmental compartments etc. Here we describe the different families of plastic additives, which come with different chemical structures and polarities, and the way they migrate from plastic material to contact matrices. Then the extraction and analysis methods to determine plastic additives in materials and contact matrices are detailed. Many examples are presented to explain the particularities of extraction and analysis methods, comprising spectroscopic, chromatographic and thermal analyses. Comparison tables are provided to guide researchers looking for extraction or analysis methods, depending on the type of matrices examined. Finally, the areas where further research is necessary are detailed.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"191 ","pages":"Article 118373"},"PeriodicalIF":11.8,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144696648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intra- and inter-individual variation of the human lipidome 人类脂质组的个体内和个体间变异

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2025-07-12 DOI: 10.1016/j.trac.2025.118368

Anh Hoang Nguyen , Habtamu B. Beyene , Gabriele Mocciaro , Lisa Hahnefeld , Santosh Lamichhane , Mikael Fabritius , Henri Avela , Yuqin Wang , Alex M. Dickens , Robert Gurke , Baoru Yang , William J. Griffiths , Tuulia Hyötyläinen , Peter J. Meikle , Matej Orešič

{"title":"Intra- and inter-individual variation of the human lipidome","authors":"Anh Hoang Nguyen , Habtamu B. Beyene , Gabriele Mocciaro , Lisa Hahnefeld , Santosh Lamichhane , Mikael Fabritius , Henri Avela , Yuqin Wang , Alex M. Dickens , Robert Gurke , Baoru Yang , William J. Griffiths , Tuulia Hyötyläinen , Peter J. Meikle , Matej Orešič","doi":"10.1016/j.trac.2025.118368","DOIUrl":"10.1016/j.trac.2025.118368","url":null,"abstract":"<div><div>Lipids play essential roles in cellular functions such as membrane structure, signaling, and energy storage. Lipidomics—global study of lipids in cells and tissues—seeks to identify biomarkers and uncover underlying metabolic pathways. Human lipid concentrations in cells and biofluids can fluctuate at multiple temporal scales, reflecting normal biochemical and physiological variation, or responses to various internal and external stimuli. Understanding both intra- and inter-individual lipid variability is crucial for accurate lipidomics study design and interpretation. This knowledge also supports personalized healthcare, moving beyond static reference ranges. Here, we review key drivers of intra-individual variation, including diet, circadian rhythms, sleep, environmental exposures, and physiological states. We also examine inter-individual factors such as genetics, age, sex, microbiome composition, and medications. Finally, we discuss how these variables interact and influence lipidomics outcomes, aiming to enhance reproducibility and guide future research.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"191 ","pages":"Article 118368"},"PeriodicalIF":11.8,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144662570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Non-Destructive Spectral Systems (NDSS) for modern inspection systems in real-time: challenges and industrial perspectives 用于现代实时检测系统的无损光谱系统（NDSS）：挑战和工业前景

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2025-07-12 DOI: 10.1016/j.trac.2025.118369

Jose Blasco , Giulia Gorla , Sandra Munera , Raffaele Vitale , Jose Manuel Amigo

{"title":"Non-Destructive Spectral Systems (NDSS) for modern inspection systems in real-time: challenges and industrial perspectives","authors":"Jose Blasco , Giulia Gorla , Sandra Munera , Raffaele Vitale , Jose Manuel Amigo","doi":"10.1016/j.trac.2025.118369","DOIUrl":"10.1016/j.trac.2025.118369","url":null,"abstract":"<div><div>The demand for efficient, accurate, and non-invasive inspection methodologies has led to the emergence of Non-Destructive Spectral Systems (NDSS) as transformative tools. NDSS, in combination with chemometrics, enables rapid and precise analyses without damaging the sample, revolutionising traditional inspection approaches and offering accurate quantification and classification, process optimisation, and cost reduction capabilities. This review highlights the principles, advancements, and real-time applications of NDSS in product inspection and quality assurance. Recent technological innovations, data acquisition, computational algorithms, and their applications in the agri-food, pharmaceutical, and environmental monitoring sectors are explored. Furthermore, the challenges associated with their adoption for real-time implementations, including computational demands, calibration complexities, and environmental variability, are discussed. Case studies and emerging research directions provide a comprehensive outlook on the potential of NDSS to address evolving industrial needs. This review underscores the pivotal role of NDSS in enhancing operational efficiency, ensuring product quality, and driving future advancements in analytical instrumentation.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"191 ","pages":"Article 118369"},"PeriodicalIF":11.8,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144654466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular recognition polymer microspheres and nanoparticles for nonseparation assays: the Mosbach imprint 用于非分离分析的分子识别聚合物微球和纳米颗粒：莫斯巴赫印记

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2025-07-12 DOI: 10.1016/j.trac.2025.118370

Lei Ye, Tong Zhang, Qicheng Zhang

{"title":"Molecular recognition polymer microspheres and nanoparticles for nonseparation assays: the Mosbach imprint","authors":"Lei Ye, Tong Zhang, Qicheng Zhang","doi":"10.1016/j.trac.2025.118370","DOIUrl":"10.1016/j.trac.2025.118370","url":null,"abstract":"<div><div>Synthesis of molecularly imprinted polymer microspheres using precipitation polymerization was first reported in 1999 in Lund. The synthetic approach attracted great interest for molecular imprinters worldwide due to its simplicity. Following the initial demonstration of feasibility for material synthesis, imprinted polymer microspheres were found to exhibit good colloidal stability qualifying for use as antibody substitutes in a proximity scintillation assay. In the following years, other types of nonseparation assays using imprinted polymer microspheres started to be developed. Molecular detection based on fluorescence measurements eventually became the method of choice to avoid radioactive tracers. Many of the research ideas have been inspired by the earlier contributions from Professor Klaus Mosbach. This manuscript provides a historic review on molecularly imprinted polymer microspheres and nanoparticles designed for nonseparation assays. While the main thread is the research evolvement of the authors’ laboratory till the present time, important contributions from other groups are also discussed.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"191 ","pages":"Article 118370"},"PeriodicalIF":11.8,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144614695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Engineering positive feedback in nucleic acid circuit Biosensors: Design and applications 工程正反馈的核酸电路生物传感器：设计与应用

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2025-07-10 DOI: 10.1016/j.trac.2025.118367

Shuang Zhao , Xuesong Wang , Meilin Gong , Zuowei Xie , Jingsen Cao , Ming Chen , Kai Chang

{"title":"Engineering positive feedback in nucleic acid circuit Biosensors: Design and applications","authors":"Shuang Zhao , Xuesong Wang , Meilin Gong , Zuowei Xie , Jingsen Cao , Ming Chen , Kai Chang","doi":"10.1016/j.trac.2025.118367","DOIUrl":"10.1016/j.trac.2025.118367","url":null,"abstract":"<div><div>Positive feedback refers to a process in which a system's output signal redirected to its input and superimposed in the same direction, causing progressive amplification. Integrating positive feedback loops into biosensor design has become a powerful strategy for efficient sensitivity improvement, enabling trace biomarkers detection. Recent advancements have applied cutting-edge technologies, such as DNAzymes, nucleic acid-modifying enzymes, and CRISPR/Cas systems, to engineer positive feedback loop in nucleic acid circuit biosensors with exceptional detection capability, cost-effectiveness, and robustness. This review first explained the mechanism of positive feedback-driven signal amplification and deconstructs the design principles of positive feedback nucleic acid circuit biosensors. It then systematically reviews representative studies, highlighting design innovations and comparing their performance. Finally, the current challenges and future directions were discussed. This review aims to clarify the design logic of positive feedback biosensors and inspire the development of next-generation biosensors with enhanced detection performance.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"191 ","pages":"Article 118367"},"PeriodicalIF":11.8,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144604867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Ratiometric afterglow luminescence: Emerging paradigm for reliable quantitative bio-imaging and disease monitoring 比率余辉发光：可靠定量生物成像和疾病监测的新兴范例

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2025-07-09 DOI: 10.1016/j.trac.2025.118366

Meng Yuan , Shuaiming Bao , Kejun Wu , Zixin Deng , Huanghao Yang , Jiangtao Gao

{"title":"Ratiometric afterglow luminescence: Emerging paradigm for reliable quantitative bio-imaging and disease monitoring","authors":"Meng Yuan , Shuaiming Bao , Kejun Wu , Zixin Deng , Huanghao Yang , Jiangtao Gao","doi":"10.1016/j.trac.2025.118366","DOIUrl":"10.1016/j.trac.2025.118366","url":null,"abstract":"<div><div>Ratiometric afterglow luminescence has emerged as a transformative approach for quantitative bio-imaging and disease monitoring, addressing fundamental limitations in conventional imaging techniques. This review examines recent advancements in ratiometric afterglow probes, concentrating on their design principles, energy transfer mechanisms, and applications in disease detection. The integration of dual-emission capabilities with prolonged luminescence enables reliable quantification by eliminating background interference and providing internal calibration. Recent advances have demonstrated exceptional performance in monitoring cancer immunotherapy, arthritis progression, and brain tumor development through the detection of specific biomarkers. Despite significant progress, challenges remain in material design, signal stability, and clinical translation. The review examines current engineering solutions and emerging opportunities, particularly in the integration of artificial intelligence, multiplexed sensing, and the development of point-of-care diagnostics. These advances establish ratiometric afterglow luminescence as a powerful platform for next-generation biomedical imaging and disease monitoring systems.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"191 ","pages":"Article 118366"},"PeriodicalIF":11.8,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144596637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advances in fluorescent sensors for trace detection of metal contaminants and agrochemical residues in soil: A comprehensive review 荧光传感器在土壤中痕量金属污染物和农药残留检测中的研究进展

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2025-07-09 DOI: 10.1016/j.trac.2025.118365

Hasher Irshad, Khadija, Katrine Qvortrup

{"title":"Advances in fluorescent sensors for trace detection of metal contaminants and agrochemical residues in soil: A comprehensive review","authors":"Hasher Irshad, Khadija, Katrine Qvortrup","doi":"10.1016/j.trac.2025.118365","DOIUrl":"10.1016/j.trac.2025.118365","url":null,"abstract":"<div><h3>Background</h3><div>Soil contamination by hazardous substances, including heavy metal ions and agrochemical residues such as herbicides, insecticides and fungicides poses a significant threat to environmental safety and human health. Reliable detection methods for trace levels of these contaminants are essential to address the risks associated with their presence in soil.</div></div><div><h3>Scope and approach</h3><div>This review highlights recent advancements in the development of fluorescent sensors for the trace detection of contaminants in soil samples. The discussion encompasses the properties of various fluorescent materials, their selectivity, limit of detection, sensing strategies and mechanisms.</div></div><div><h3>Key findings and conclusions</h3><div>Fluorescent sensors have demonstrated exceptional potential for detecting soil contaminants due to their high sensitivity, specificity, and rapid response. Advances in sensor design, including the development of novel materials and portable detection systems, have significantly improved detection capabilities. Future research should focus on enhancing the reliability of fluorescent signals, developing reusable, portable and user-friendly systems, and improving the applicability of these sensors to real soil analysis.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"191 ","pages":"Article 118365"},"PeriodicalIF":11.8,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144696680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A paradigm shift in sample preparation using sustainable membrane phases: Hype or reality? 使用可持续膜相制备样品的范式转变：炒作还是现实？

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2025-07-08 DOI: 10.1016/j.trac.2025.118364

Francisco Antonio Casado-Carmona , Noemí Aranda-Merino , José Manuel Herrero-Martínez , Yolanda Moliner-Martínez , Soledad Cárdenas , Manuel Miró

{"title":"A paradigm shift in sample preparation using sustainable membrane phases: Hype or reality?","authors":"Francisco Antonio Casado-Carmona , Noemí Aranda-Merino , José Manuel Herrero-Martínez , Yolanda Moliner-Martínez , Soledad Cárdenas , Manuel Miró","doi":"10.1016/j.trac.2025.118364","DOIUrl":"10.1016/j.trac.2025.118364","url":null,"abstract":"<div><div>In the field of sample preparation, a vast amount of effort over the past decade has been geared toward the development of sustainable liquid and sorptive phases with green credentials and practicality to solve analytical challenges. Notwithstanding the main types and formats of biodegradable and renewable materials encompass bead and solid-fiber type arrangements, sustainable materials are readily amenable to membrane-based microextraction. In this manuscript, the role of biomembranes and biomembrane composites incorporating nanostructured materials, biomolecules and hydrophobic natural solvents for the isolation and preconcentration of organic and inorganic pollutants based on thin film microextraction, supported liquid-phase microextraction and electromembrane extraction is discussed in detail. Insights into the physicochemical properties that endow these biomembranes with unique features for extraction procedures in environmental, food, and biological matrices along with challenges to make them competitive in terms of analytical properties against synthetic polymer phases are highlighted. The potential of integrating planar biomembranes in automatic flow systems and performing on-site screening protocols with chromogenic polymeric membranes is also underscored.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"191 ","pages":"Article 118364"},"PeriodicalIF":11.8,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144654465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent advances in terahertz biochemical sensing technology: principles, evolution and applications 太赫兹生物化学传感技术的最新进展：原理、发展与应用

IF 11.8 1区化学

Trends in Analytical Chemistry Pub Date : 2025-07-03 DOI: 10.1016/j.trac.2025.118362

Chen Wang , Xiaonan Li , Aichen Wang , Junwen Bai , Zhiming Guo

引用次数: 0