Jéssica Rocha Camargo , Luiz Otávio Orzari , Jéssica de Souza Rodrigues , Lucas Felipe de Lima , Thiago Regis Longo Cesar Paixão , Leonardo Fernandes Fraceto , Bruno Campos Janegitz
{"title":"Advancements in disposable electrochemical systems for sustainable agriculture monitoring: Trends, gaps, and applied examples","authors":"Jéssica Rocha Camargo , Luiz Otávio Orzari , Jéssica de Souza Rodrigues , Lucas Felipe de Lima , Thiago Regis Longo Cesar Paixão , Leonardo Fernandes Fraceto , Bruno Campos Janegitz","doi":"10.1016/j.trac.2024.117968","DOIUrl":"10.1016/j.trac.2024.117968","url":null,"abstract":"<div><p>The potential use of disposable electrochemical systems in sustainable agriculture has revolutionized monitoring and management practices. Portable and compact electrochemical sensors have facilitated widespread application in all agricultural sectors, enabling real-time monitoring and data collection. These sensors provide a cost-effective solution for continuous monitoring, reducing the cost of farm management and improving accessibility, especially for small farmers. Integration with Internet of Things (IoT) platforms and smart devices enables automated data collection, remote monitoring, and precise control of agricultural activities. Advances in sensor materials and manufacturing techniques have improved the sensitivity and specificity of sensors, enabling accurate detection of a wide range of analytes. However, the development of sensors that can withstand extreme temperatures and humidity remains a hurdle. Effective data management systems and user-friendly interfaces are crucial for handling large amounts of data and providing actionable insights for farmers. The research into sustainable and biodegradable sensor materials is essential to minimize environmental impact and promote environmentally friendly farming practices. In this way, advances in disposable electrochemical systems are transforming sustainable agriculture by providing innovative solutions for monitoring and management. Addressing current challenges through ongoing research and development will further improve the effectiveness and acceptance of these technologies in agriculture. This review highlights recent advances in sustainable agriculture monitoring and emphasizes their central role in agricultural sustainability and productivity as well as the trends for this subject over the next few years.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"180 ","pages":"Article 117968"},"PeriodicalIF":11.8,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142230424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Magdalena Matczuk , Lena Ruzik , Andrei R. Timerbaev
{"title":"Recent development of CE-ICP-MS in biospeciation research and analysis: From anticancer drugs to nanoparticles and beyond","authors":"Magdalena Matczuk , Lena Ruzik , Andrei R. Timerbaev","doi":"10.1016/j.trac.2024.117967","DOIUrl":"10.1016/j.trac.2024.117967","url":null,"abstract":"<div><p>Capillary electrophoresis (CE) coupled to ICP-MS occupies its rightful place in mainstream biospeciation analysis, where this coupling is certainly much more than a complementary tool to the other separation-based techniques. This brief review critically discusses the current and emerging capabilities of CE-ICP-MS in the simultaneous detection of chemical species of a given element occurring in samples of biological origin, with a particular focus placed on the areas of metal-based drug and nanoparticle research. The most advantageous separation and detection strategies and the method's analytical performance are illustrated with a selection of real-world applications from recent literature. Among the methodological trends, using tandem and single-particle ICP-MS technology steadily moves to the frontline. Further progress in the field would keep step with more reliable, versatile, and robust CE-ICP-MS assays suitable for routine use.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"180 ","pages":"Article 117967"},"PeriodicalIF":11.8,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0165993624004503/pdfft?md5=09454d84d4f60bfb79b82c94f3bf86c5&pid=1-s2.0-S0165993624004503-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142241355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tingting Han , Chen Cui , Yujun Xing , Jianrong Shi , Jianhong Xu , Jun-Jie Zhu
{"title":"Advances of signal amplification strategies and sensing formats in electrochemiluminescence sensors for mycotoxins","authors":"Tingting Han , Chen Cui , Yujun Xing , Jianrong Shi , Jianhong Xu , Jun-Jie Zhu","doi":"10.1016/j.trac.2024.117961","DOIUrl":"10.1016/j.trac.2024.117961","url":null,"abstract":"<div><p>Mycotoxins are toxic secondary metabolites produced by fungus, which has carcinogenicity, teratogenicity, mutagenicity, and immunotoxicity, posing a serious hazard to food safety and public health. Therefore, it is of great importance to exploit rapid, sensitive, and universal analytical methods for mycotoxins detection to safeguard food safety and public health. Electrochemiluminescence (ECL) has been regarded as a promising analytical technology for monitoring mycotoxins in foods due to zero background and high sensitivity. Signal amplification strategies take vital roles in developing advanced ECL biosensors with high sensitiveness. Besides, deep insights into sensing formats and patterns will favour in designing innovative ECL sensors. In this review, the latest developments in various ECL sensors for mycotoxins assays are summarized, with emphasis on signal enhancement strategies and sensing formats in their applications. The opportunities and challenges are also discussed in the development and application of advanced ECL sensors for mycotoxins analysis.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"180 ","pages":"Article 117961"},"PeriodicalIF":11.8,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142162875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Skin-contact wearable electrochemical biosensing tools: A perspective for the wellbeing of neurological patients","authors":"Ilaria Antonia Vitale , Neri Fuochi , Daniele Martella , Camilla Parmeggiani , Giovanna Marrazza , Ilaria Palchetti","doi":"10.1016/j.trac.2024.117965","DOIUrl":"10.1016/j.trac.2024.117965","url":null,"abstract":"<div><p>Neurological Disorders (NDs) have become more prevalent with the increase of life expectancy. Wearable devices are particularly appealing for NDs since they would strongly facilitate the continuous health status monitoring in people that are not capable of communicating their needs or discomfort. This review summarizes the studies over the past five years reported in the literature regarding sampling and biosensing solutions for the development of wearable electroanalytical platforms. Our survey is mainly focused on skin-contact wearable biosensors, with a special emphasis on sweat sampling and analysis using biocompatible materials. Examples of devices for monitoring chemical parameters involved in the wellbeing of ND patients are discussed.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"180 ","pages":"Article 117965"},"PeriodicalIF":11.8,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0165993624004485/pdfft?md5=b1b6166529a9c59e520c3db3a865f5d0&pid=1-s2.0-S0165993624004485-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142241358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Linjie Wang , Yang Ji , Yixin Chen, Shujun Zheng, Fei Wang, Caolong Li
{"title":"Recent research progress of fluorescence biosensors based on carbon dots in early diagnosis of diseases","authors":"Linjie Wang , Yang Ji , Yixin Chen, Shujun Zheng, Fei Wang, Caolong Li","doi":"10.1016/j.trac.2024.117962","DOIUrl":"10.1016/j.trac.2024.117962","url":null,"abstract":"<div><p>Recently, numerous exceptional optical nanomaterials have attracted increasing attention due to their superiority in improving assay performance of fluorescent biosensors for early disease diagnosis. Among them, carbon dots (CDs) stand out due to their unique optical properties, non-toxicity, cheap synthesis costs, and good biocompatibility. As extremely advantageous fluorescent probes, the CDs-based fluorescent biosensors are expected to become great attractive candidates for early clinical disease diagnosis. This review has carefully summarized the research progress of CDs-based fluorescence biosensors for early disease diagnosis. Firstly, the common synthesis methods, luminescent mechanisms, and sensing mechanisms of CDs were briefly introduced and discussed. Subsequently, the various applications of CDs in fluorescence biosensing and biological imaging were emphasized, which were reasonably classified based on recognition modes, including direct identification, identification through medium, enzyme, antibody, aptamer, and molecularly imprinted polymer (MIP). Eventually, the future opportunities, challenges, and development trends of CDs-based fluorescent biosensors in early disease diagnosis were also carefully discussed.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"180 ","pages":"Article 117962"},"PeriodicalIF":11.8,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142163556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xing-Hai Wang , Ya-Hui Wen , Pei-Yi Li , Yuan-Xin Li , Hai-Yang Qin , Jin-Xue Zhao , Xue-Jing Zhai , Wen-Chao Yang , Li-Dong Wu
{"title":"Flexible sensors for precision agriculture: A mini review","authors":"Xing-Hai Wang , Ya-Hui Wen , Pei-Yi Li , Yuan-Xin Li , Hai-Yang Qin , Jin-Xue Zhao , Xue-Jing Zhai , Wen-Chao Yang , Li-Dong Wu","doi":"10.1016/j.trac.2024.117946","DOIUrl":"10.1016/j.trac.2024.117946","url":null,"abstract":"<div><p>In recent years, there has been extensive research into flexible sensors within the field of precision agriculture. This interest stems from their ability to integrate a diverse array of functional materials, including SERS-active substrates, noble metal nanoparticles, graphene, MXenes, and flexible transparent polymer films. In comparison to conventional sensors, flexible sensors present enhanced sensitivity, broader versatility, and superior stability. This review systematically illustrates the preparation methods and potential applications of flexible sensors in agricultural field. Furthermore, the article underscores the promising research prospects in agricultural detection enabled by these advancements.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"180 ","pages":"Article 117946"},"PeriodicalIF":11.8,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142172540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Recent progress and challenges in biosensing of carcinoembryonic antigen","authors":"Mojtaba Afshari Babazad , Amin Foroozandeh , Majid Abdouss , Hossein SalarAmoli , Reyhaneh Afshari Babazad , Mohammad Hasanzadeh","doi":"10.1016/j.trac.2024.117964","DOIUrl":"10.1016/j.trac.2024.117964","url":null,"abstract":"<div><p>Carcinoembryonic antigen (CEA) is a multifunctional glycoprotein that belongs to the immunoglobulin superfamily and plays dual regulatory roles in cancer and fetal development. Due to its crucial biological functions in cancer regulation, CEA levels elevate abnormally in colorectal, breast, lung, gastric, medullary thyroid, and pancreatic cancers. Furthermore, conditions unrelated to neoplasms, such as ulcerative pancreatitis, chronic obstructive pulmonary disease (COPD), cirrhosis, colitis, hypothyroidism, Crohn's disease, and smoking are associated with increased CEA levels. Therefore, developing precise and sensitive strategies for monitoring CEA holds significant importance. This study emphasizes the successful creating of detection methods through surface modification, bio-functionalization, and nano-fabrication to enable effective detection of CEA at trace levels (with a threshold of 20 ng mL<sup>−1</sup>). It explores various optical and electrochemical (EC) sensors, including electrochemiluminescence (ECL), fluorometric, surface-enhanced Raman scattering (SERS), photoelectrochemical (PEC), and colorimetric methods. The study highlights the integrating of innovative nanomaterials with a range of bioreceptor elements, including peptides, aptamers (Apt), DNA, enzymes, and antibodies (Abs), to enhance the effectiveness of CEA tracking and quantification, which are essential for analytical methods. Additionally, the research identifies gaps, challenges, and areas for improvement in CEA biosensing methods, research, and technology. This review represents an unprecedented assessment of CEA tracking through the application of biosensor technology.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"180 ","pages":"Article 117964"},"PeriodicalIF":11.8,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0165993624004473/pdfft?md5=5efc7be29603bad230fbeb65324203d3&pid=1-s2.0-S0165993624004473-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142163554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Huimin Yuan , Wen-jing Liu , Juan Hu, Chun-yang Zhang
{"title":"Recent advances in single-nucleotide variant assay: From in vitro detection to in vivo imaging","authors":"Huimin Yuan , Wen-jing Liu , Juan Hu, Chun-yang Zhang","doi":"10.1016/j.trac.2024.117963","DOIUrl":"10.1016/j.trac.2024.117963","url":null,"abstract":"<div><p>Single-nucleotide variants (SNVs) are single base changes that appear in the coding regions and non-coding regions. SNVs are closely related to multiple physiological and pathological processes, and may act as important biomarkers. Consequently, accurate and sensitive identification of SNVs is critical for medical diagnosis and disease treatment. In recent years, a series of novel SNV detection methods have been developed, but an overview of <em>in vitro</em> detection and <em>in vivo</em> imaging of SNVs is lacking. Herein, we review the emerging methods for <em>in vitro</em> and <em>in vivo</em> SNV assays in the past few years. The <em>in vitro</em> SNV detection methods are categorized into five types including fluorescent, colorimetric, electrochemical, electrochemiluminescent, and chemiluminescent methods, while the <em>in vivo</em> SNV assays mainly rely on fluorescence imaging. We summarize the characteristics, principles, performances, and applications of these methods, and discuss the existing challenges and trends in this area.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"180 ","pages":"Article 117963"},"PeriodicalIF":11.8,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142163555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yanchen Li , Zike Wang , Tianning Zhao , Hua Li , Jingkun Jiang , Jianhuai Ye
{"title":"Electronic nose for the detection and discrimination of volatile organic compounds: Application, challenges, and perspectives","authors":"Yanchen Li , Zike Wang , Tianning Zhao , Hua Li , Jingkun Jiang , Jianhuai Ye","doi":"10.1016/j.trac.2024.117958","DOIUrl":"10.1016/j.trac.2024.117958","url":null,"abstract":"<div><p>The electronic nose, commonly referred to as e-nose, has become an essential tool for the detection of volatile organic compounds (VOCs) which play critical roles in air quality, climate change, and human health. Inspired from the human olfactory system, e-noses offer key advantages in portability and cost-effectiveness, making them indispensable for identifying a series of VOCs. This review explores advancements in e-nose technology for VOC detection, detailing the operational principles of various sensors, and assessing their strengths and weaknesses. It also examines the conventional and novel algorithms for VOC pattern recognition, highlighting their role in enhancing detection accuracy and application robustness. Moreover, the review discusses the diverse applications of e-noses, ranging from environmental monitoring to critical sectors such as food processing and medical diagnostics. Finally, the review addresses current challenges in e-nose applications, such as selectivity and sensitivity, and offers insights into emerging trends and future perspectives in e-nose development.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"180 ","pages":"Article 117958"},"PeriodicalIF":11.8,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142168625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lorenzo Strani , Caterina Durante , Marina Cocchi , Federico Marini , Ingrid Måge , Alessandra Biancolillo
{"title":"Data fusion strategies for the integration of diverse non-destructive spectral sensors (NDSS) in food analysis","authors":"Lorenzo Strani , Caterina Durante , Marina Cocchi , Federico Marini , Ingrid Måge , Alessandra Biancolillo","doi":"10.1016/j.trac.2024.117957","DOIUrl":"10.1016/j.trac.2024.117957","url":null,"abstract":"<div><p>The evolving landscape of agri-food systems, driven by climate change and population growth, necessitates innovative approaches to ensure food integrity, safety, and sustainability. This review explores the role of data fusion strategies, particularly focusing on non-destructive spectroscopic sensors (NDSS) in three key application contexts: in-field monitoring, on/in-line food processing, and food quality authentication. Various data fusion scenarios, including fusing spectra from different spectroscopic platforms, integrating images and spectra, and combining non-spectroscopic sensor data with spectroscopic ones are reviewed. Focus is set on practical considerations, such as selecting the level of data fusion, defining blocks, variable selection, and validation methods, highlighting the importance of tailored approaches based on research aims and data characteristics.</p><p>While combining information from diverse sensors generally enhances information extraction and modelling performance, their implementation in routine applications is still limited and especially studies focused on data fusion models’ performance over time and their maintenance are lacking.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"180 ","pages":"Article 117957"},"PeriodicalIF":11.8,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0165993624004400/pdfft?md5=ba7b79557644151f18b5756a5babbdd0&pid=1-s2.0-S0165993624004400-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142148646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}