Lunzhao Yi , Wenfu Wang , Yuhua Diao , Sanli Yi , Ying Shang , Dabing Ren , Kun Ge , Ying Gu
{"title":"Recent advances of artificial intelligence in quantitative analysis of food quality and safety indicators: A review","authors":"Lunzhao Yi , Wenfu Wang , Yuhua Diao , Sanli Yi , Ying Shang , Dabing Ren , Kun Ge , Ying Gu","doi":"10.1016/j.trac.2024.117944","DOIUrl":"10.1016/j.trac.2024.117944","url":null,"abstract":"<div><p>Food quality and safety (FQS) are crucial aspects of everyone's life and health. With the rapidly advancing field of analytical sciences, there is a growing demand for intuitive, accurate, and swift control of FQS. In recent years, artificial intelligence (AI) has emerged as a great opportunity, offering unparalleled opportunities for extracting information and making decisions from complex or large datasets in areas like chromatography, mass spectrometry, and spectroscopy for the identification of FQS indicators. This review provides a comprehensive overview of AI-based technology's general algorithms for FQS indicator analysis. Additionally, it surveys AI-based methods that are at the forefront of analytical techniques and hold significant potential for enhancing the smart control of FQS indicators. Finally, we highlight key challenges and offer recommendations to accelerate progress towards intelligent FQS control.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"180 ","pages":"Article 117944"},"PeriodicalIF":11.8,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142096090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advancing breast cancer diagnosis in 3D: The transformative power of X-ray phase-contrast microtomography for virtual histology","authors":"S. Donato , D. Bonazza","doi":"10.1016/j.trac.2024.117943","DOIUrl":"10.1016/j.trac.2024.117943","url":null,"abstract":"<div><p>Breast cancer, a prevalent global malignancy in women, demands accurate tissue alteration detection for effective diagnosis and treatment. Histology, pivotal in diagnosis, faces challenges like time, limited tissue, and lacking comprehensive three-dimensional views. This review explores X-ray microtomography virtual histology as a complementary tool to address histology's limitations. Particularly, phase-contrast techniques offer non-destructive, high-resolution 3D imaging, surpassing traditional histology constraints. Phase-contrast microtomography provides valuable insights into breast tissue alterations, aiding early cancer detection and enhancing diagnostic precision. The role of synchrotron facilities and alternative validation approaches for clinical settings are discussed. Another significant aspect covered in this review is the global shortage of pathologists, which poses a major challenge in the timely and accurate diagnosis of breast cancer. Phase-contrast microtomography can support pathologists by offering digital imaging capabilities, which enable remote consultation and reduce the dependency on physical tissue sections.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"180 ","pages":"Article 117943"},"PeriodicalIF":11.8,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142122815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Challenges and possibilities for the qualitative and quantitative analysis of phosphate metabolites","authors":"Pei Zhang , Meiyu Gao , Zunjian Zhang , Fengguo Xu","doi":"10.1016/j.trac.2024.117934","DOIUrl":"10.1016/j.trac.2024.117934","url":null,"abstract":"<div><p>Phosphate metabolites (PMs) are endogenous substances that contain phosphate groups, constituting over half of the small molecules in the body. They play crucial roles in various biological processes. However, the qualitative and quantitative analysis of PMs in biological matrices remains challenging. To elucidate the current status of detection methodologies, this review summarizes existing studies on the extraction and analysis of PMs. Emphasis is placed on the chemical derivatization-based mass spectrometry (CD-MS) strategy, with a detailed examination of the types of CD reagents and the reactive groups in PMs. Additionally, emerging methods potentially applicable to PM analysis are reviewed. Finally, we discuss the challenges and future perspectives in this field. This comprehensive review aims to enhance the understanding of PM analysis, thereby facilitating their exploration in health and disease contexts.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"180 ","pages":"Article 117934"},"PeriodicalIF":11.8,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142087611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploring the potential of carbon quantum dots (CQDs) as an advanced nanomaterial for effective sensing and extraction of toxic pollutants","authors":"Hassan Elzain Hassan Ahmed , Mustafa Soylak","doi":"10.1016/j.trac.2024.117939","DOIUrl":"10.1016/j.trac.2024.117939","url":null,"abstract":"<div><p>Both organic and inorganic pollutants seriously impact the environment, human health, and ecosystems. Carbon quantum dots (CQDs) and their composites have emerged as promising materials for addressing these environmental issues due to their adaptability, efficiency, and environmentally friendly nature. This study aims to discuss the most recent developments in CQDs-based nanomaterials, focusing on their distinctive structures, synthesis methodologies, characterizations, and applications in environmental science as pollutants extractors and sensors. It studies the potential of nanomaterials based on CQDs for identifying and absorbing contaminants, focusing on their effectiveness in detecting and absorbing hazardous organic chemicals and heavy metals from different environments. The key results include the recognition of distinctive surface characteristics of CQDs-based nanomaterials, which facilitate effective interactions with various pollutants. This enhances their effectiveness in sensor applications and as constituents of extraction materials. This review emphasizes the potential of CQDs-based nanomaterials to transform pollution detection and extraction practices by providing an extensive overview of their utility in environmental science.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"180 ","pages":"Article 117939"},"PeriodicalIF":11.8,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142136282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Antonietta Carrera , Amadeo R. Fernández-Alba , María Dolores Hernando
{"title":"Unveiling bee pollen's contamination with pesticides and mycotoxins: Current analytical procedures, results and regulation","authors":"Maria Antonietta Carrera , Amadeo R. Fernández-Alba , María Dolores Hernando","doi":"10.1016/j.trac.2024.117935","DOIUrl":"10.1016/j.trac.2024.117935","url":null,"abstract":"<div><p>Bee pollen is a food supplement that is receiving increasing attention for its nutraceutical and therapeutic properties. However, several uncertainties on the safety of this beekeeping product still exist. The present work addressed this issue through the critical evaluation of 61 studies, published over the 2014–2024 period, and focused on the analysis of pesticides and mycotoxins in bee pollen. A comprehensive examination of the analytical procedures employed for the analysis of these contaminants was performed. Overall, 358 pesticides and 7 mycotoxins were found in bee pollen, with certain compounds being globally distributed and frequently encountered. An overview of the existing European regulations concerning pesticide and mycotoxin levels in food was presented, emphasizing the exclusion of bee pollen from the list of monitored commodities. The findings of the reviewed studies revealed the necessity of gathering more data on bee pollen's contamination and consumption, in order to finally perform reliable risk assessments.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"180 ","pages":"Article 117935"},"PeriodicalIF":11.8,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142087610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gabriela Flores Rangel , Lorena Diaz de León Martínez , Lisa Sophie Walter , Boris Mizaikoff
{"title":"Recent advances and trends in mid-infrared chem/bio sensors","authors":"Gabriela Flores Rangel , Lorena Diaz de León Martínez , Lisa Sophie Walter , Boris Mizaikoff","doi":"10.1016/j.trac.2024.117916","DOIUrl":"10.1016/j.trac.2024.117916","url":null,"abstract":"<div><p>The Mid-Infrared (MIR) spectral regime has gained interest in biosensor research due to the unique excitation of specific molecular vibrational, rovibrational, and rotational modes of biomarkers and biological molecules, offering inherent selectivity for biomarker detection, which is a key asset for biomedical applications. This review focuses on the role of mid-infrared sensing technologies in biomedicine, emphasizing the crucial requirement for accurate detection and real-time monitoring of biological processes in early disease diagnosis and monitoring of disease progression. Highlighted examples provide insight into the effectiveness of MIR optical biosensors for addressing key biomarkers, underscoring their potential impact in areas including but not limited to personalized medicine and clinical research. Furthermore, we discuss how recently designed and implemented microstructures enhance the sensitivity within these application scenarios. These advancements will be complemented by technical challenges inherent to this evolving field, addressing further sensitivity enhancement, device miniaturization, and system integration, along with advanced data analysis. Future strategies discussed in this review contextualize the convergence of MIR sensing, biomedicine, and the integration of artificial intelligence for comprehensive data analysis and interpretation.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"180 ","pages":"Article 117916"},"PeriodicalIF":11.8,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0165993624003996/pdfft?md5=d4498153dcc5ed9a59330389f80819a0&pid=1-s2.0-S0165993624003996-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142148644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cheng Lei , Yuta Nakagawa , Yuzuki Nagasaka , Tianben Ding , Hiroshi Kanno , Chihana Toyokawa , Kuniyasu Niizuma , Kengo Suzuki , Ming Li , Anwar Sunna , Vladimir Hampl , Keisuke Goda
{"title":"High-throughput optical imaging technology for large-scale single-cell analysis of live Euglena gracilis","authors":"Cheng Lei , Yuta Nakagawa , Yuzuki Nagasaka , Tianben Ding , Hiroshi Kanno , Chihana Toyokawa , Kuniyasu Niizuma , Kengo Suzuki , Ming Li , Anwar Sunna , Vladimir Hampl , Keisuke Goda","doi":"10.1016/j.trac.2024.117938","DOIUrl":"10.1016/j.trac.2024.117938","url":null,"abstract":"<div><p><em>Euglena gracilis</em>, a flagellated, single-celled organism shaped like a spindle, belongs to the Euglenozoa phylum. This protist is predominantly found in freshwater bodies such as lakes and ponds. Unique in its ability to perform photosynthesis and heterotrophic feeding, <em>E. gracilis</em> can produce organic materials on its own or absorb them from the environment. This intriguing blend of plant and animal traits, coupled with promising biotechnological applications, have made it a subject of extensive research. Notably, <em>E. gracilis</em> has been used for biofuel production and synthesis of various compounds such as amino acids and vitamins. For these applications, rapid assessment of single <em>E. gracilis</em> cells within populations is essential. This paper introduces recent advancements in high-throughput optical imaging technology that enables large-scale, single-cell analysis of <em>E. gracilis</em>. We review the benefits and limitations of various methods within this technology, along with discussing its future potential.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"180 ","pages":"Article 117938"},"PeriodicalIF":11.8,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0165993624004217/pdfft?md5=4b9c14af1f882940aeb473eda8677459&pid=1-s2.0-S0165993624004217-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142130152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Corrigendum to “Offline preparative separation methods based on electromigration: An overview and current trends” [Trac. Trends Anal. Chem. 170 (2023) 117428]","authors":"Helena Hrušková , Roman Řemínek , František Foret","doi":"10.1016/j.trac.2024.117933","DOIUrl":"10.1016/j.trac.2024.117933","url":null,"abstract":"","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"180 ","pages":"Article 117933"},"PeriodicalIF":11.8,"publicationDate":"2024-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0165993624004163/pdfft?md5=8b5368af8f51dd6f4741e8d5398034bd&pid=1-s2.0-S0165993624004163-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142049290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Biosensor technologies: DNA-based approaches for foodborne pathogen detection","authors":"Mongkol Techakasikornpanich , Kulachart Jangpatarapongsa , Duangporn Polpanich , Nadia Zine , Abdelhamid Errachid , Abdelhamid Elaissari","doi":"10.1016/j.trac.2024.117925","DOIUrl":"10.1016/j.trac.2024.117925","url":null,"abstract":"<div><p>Foodborne diseases are a global concern due to their high impact on morbidity, and mortality worldwide. The traditional method of bacterial detection is both time-consuming and labor-intensive. Alternative methods, such as immunoassays and polymerase chain reactions, have limited applicability due to the need for an enrichment process and expensive equipment. DNA-based biosensors have gained interest in the field of detection, due to their high rapidity, high sensitivity, and high specificity, which provides a promising technology for bacterial detection. To fabricate DNA-based biosensors, the immobilization of DNA probes on electrodes is a crucial process. This review delves into the three techniques of DNA probe immobilization, discussing their respective advantages and disadvantages. Furthermore, recent advancements in DNA-based biosensors are explored. The integration of advanced molecular techniques such as DNA nanostructures, DNA walkers, and the CRISPR-Cas system with DNA-based biosensors for foodborne pathogens is also discussed in this work.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"180 ","pages":"Article 117925"},"PeriodicalIF":11.8,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142136279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Federico N. Castañeda, Daiana L. Prince, Sofía R. Peirano, Sol Giovannoni, Romina N. Echevarría, Sonia Keunchkarian, Mario Reta
{"title":"“New sorbents for sample pretreatment: Development and applications”","authors":"Federico N. Castañeda, Daiana L. Prince, Sofía R. Peirano, Sol Giovannoni, Romina N. Echevarría, Sonia Keunchkarian, Mario Reta","doi":"10.1016/j.trac.2024.117924","DOIUrl":"10.1016/j.trac.2024.117924","url":null,"abstract":"<div><p>Sample preparation prior to instrumental analysis is a key step to achieve high quality qualitative/quantitative analytes determinations present in complex samples. Development of pretreatment methods, with the aim of preconcentrate analyte(s) of interest or isolating them from their matrices which may contain possible interferents, has been a continuous task over the years. Multiple goals are pursued to obtain improved pretreatment methods, such as low sample consumption, specificity or selectivity, high throughput, simplicity, robustness, as well as reducing economic costs. In recent years, sample pretreatment has also focused on reducing environmental pollution and enabling miniaturization and automation. Therefore, classic methods of liquid-liquid extraction and liquid-solid extraction are being replaced at a significant rate by miniaturized techniques such as single-drop microextraction, dispersive liquid-liquid microextraction, solid-phase microextraction, dispersive solid phase microextraction, microextraction with packed sorbents, among others, using a wide variety of sorbents, including monolithic polymers, metal-organic frameworks, carbon-based and magnetic nanomaterials. This review summarizes the most relevant progress achieved in the last five years on advanced sorbent materials for sample preparation. In addition, most employed miniaturized solid phase extraction techniques and their applications to extraction of organic compounds in complex matrices were considered. Advantages and disadvantages, analytical performance, as well as their underlying principles and environmental benefits are discussed. Several applications of these modern materials in sample preparation methods are shown and future trends in the development of new sorbents used are proposed.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"180 ","pages":"Article 117924"},"PeriodicalIF":11.8,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142049142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}