Trends in Analytical Chemistry最新文献

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Hybrid enzymatic and nanozymatic biofuel cells for wearable and implantable biosensors
IF 11.8 1区 化学
Trends in Analytical Chemistry Pub Date : 2025-01-28 DOI: 10.1016/j.trac.2025.118169
Xin Luo , Shentian Li , Yu Wu , Feilong Tan , Cao Li , Wenling Gu , Juewen Liu , Chengzhou Zhu
{"title":"Hybrid enzymatic and nanozymatic biofuel cells for wearable and implantable biosensors","authors":"Xin Luo ,&nbsp;Shentian Li ,&nbsp;Yu Wu ,&nbsp;Feilong Tan ,&nbsp;Cao Li ,&nbsp;Wenling Gu ,&nbsp;Juewen Liu ,&nbsp;Chengzhou Zhu","doi":"10.1016/j.trac.2025.118169","DOIUrl":"10.1016/j.trac.2025.118169","url":null,"abstract":"<div><div>The increasing demand for wearable and implantable devices presents unprecedented opportunities for advancing self-powered systems (SPSs). Enzymatic biofuel cells (BFCs), which harvest energy through biochemical reactions, hold great potential in SPSs. However, their practical applications are constrained by challenges, including low power output and limited long-term stability. Integrating the advantages of enzymes with nanomaterials, hybrid enzymatic BFCs achieve improved electron transfer efficiency, operational stability, and mechanical flexibility. Nanozymes, as nanomaterial-based artificial enzymes, provide promising approaches to these limitations with their lost cost, high stability, and tunable properties. This review highlights recent research advances in hybrid enzymatic and nanozymatic BFCs for wearable and implantable biosensors, including applications in detecting small molecules, biomacromolecules, cells, and systems integrating diagnosis and treatment. Specifically, the advantage of nanomaterials in signal amplification strategies for SPSs is emphasized. Finally, a personal perspective on challenges and future opportunities for advancing BFCs in wearable and implantable biosensors is discussed.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"185 ","pages":"Article 118169"},"PeriodicalIF":11.8,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143164711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recent advances in molecularly imprinted polymers for glycosylated molecule analysis
IF 11.8 1区 化学
Trends in Analytical Chemistry Pub Date : 2025-01-28 DOI: 10.1016/j.trac.2025.118168
Muhammad Mujahid Ali , Xingguo Liu , Farrukh Raza Amin , Juntao Zhou , Lianghai Hu
{"title":"Recent advances in molecularly imprinted polymers for glycosylated molecule analysis","authors":"Muhammad Mujahid Ali ,&nbsp;Xingguo Liu ,&nbsp;Farrukh Raza Amin ,&nbsp;Juntao Zhou ,&nbsp;Lianghai Hu","doi":"10.1016/j.trac.2025.118168","DOIUrl":"10.1016/j.trac.2025.118168","url":null,"abstract":"<div><div>Glycosylated molecules play pivotal roles in numerous biological processes and are implicated in various diseases, making their selective detection and isolation essential for biomedical research and clinical applications. In recent years, molecularly imprinted polymers (MIPs) have emerged as promising materials for the specific recognition and capture of glycosylated molecules. This review provides an overview of the recent advances in the development of MIPs tailored for glycosylated molecules. Furthermore, this review addresses the challenges associated with the development of these polymer-based systems, such as their stability and biocompatibility, and proposes innovative solutions derived from recent research findings. Finally, the review concludes with a perspective on future directions and challenges in the field, highlighting the need for continued research to address issues such as scalability, efficiency and real-world applicability.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"185 ","pages":"Article 118168"},"PeriodicalIF":11.8,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143198116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recent advances of magnetic microporous organic networks in magnetic solid phase extraction
IF 11.8 1区 化学
Trends in Analytical Chemistry Pub Date : 2025-01-28 DOI: 10.1016/j.trac.2025.118171
Chun-Ying Xu, Yuan-Yuan Cui, Cheng-Xiong Yang
{"title":"Recent advances of magnetic microporous organic networks in magnetic solid phase extraction","authors":"Chun-Ying Xu,&nbsp;Yuan-Yuan Cui,&nbsp;Cheng-Xiong Yang","doi":"10.1016/j.trac.2025.118171","DOIUrl":"10.1016/j.trac.2025.118171","url":null,"abstract":"<div><div>Magnetic microporous organic networks (MMONs) integrate the unique properties of MONs and magnetic nanoparticles, emerging as a novel and advanced class of magnetic adsorbents in magnetic solid-phase extraction (MSPE). These materials have recently received considerable attention in sample pretreatment. This review provides a detailed overview of the types, synthesis methods, and modification strategies of MMONs and their composites, with a focus on recent research. The application of MMONs in the MSPE of various organic pollutants, such as drugs, pesticides, endocrine disrupting chemicals, mycotoxins, food additives, and per- and polyfluoroalkyl substances, is discussed in detail. Furthermore, the extraction mechanisms between MMONs and analytes are elucidated. Finally, the challenges and prospects of MMONs are discussed. This review enhances the current understanding of MMONs-based MSPE methods for various chemical pollutants as well as provides guidance for the synthesis and application of MMONs.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"185 ","pages":"Article 118171"},"PeriodicalIF":11.8,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143164714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multidimensional single-cell analysis: Diverse strategies and emerging applications in the life sciences
IF 11.8 1区 化学
Trends in Analytical Chemistry Pub Date : 2025-01-28 DOI: 10.1016/j.trac.2025.118170
Boyang Zhang , Xinyue Lan , Siyuan Tan , Zehu Xie , Longjiao Zhu , Xiaoyun Gong , Xinhua Dai , Xiang Fang , Wentao Xu
{"title":"Multidimensional single-cell analysis: Diverse strategies and emerging applications in the life sciences","authors":"Boyang Zhang ,&nbsp;Xinyue Lan ,&nbsp;Siyuan Tan ,&nbsp;Zehu Xie ,&nbsp;Longjiao Zhu ,&nbsp;Xiaoyun Gong ,&nbsp;Xinhua Dai ,&nbsp;Xiang Fang ,&nbsp;Wentao Xu","doi":"10.1016/j.trac.2025.118170","DOIUrl":"10.1016/j.trac.2025.118170","url":null,"abstract":"<div><div>Multidimensional single-cell analysis is an outstanding tool in life sciences, enabling the study of diverse biomolecules, including nucleic acids, epigenetic factors, proteins, and metabolites. The main strategies in this field are nucleic acid amplification-based sequencing and mass spectrometry (MS)-based molecule detection. With the commercialization of high-throughput sequencing platforms and advances in MS-based molecule detection, single-cell omics analyses have rapidly developed, enabling the exploration of single-cell metabolomics and proteomics. This work provides a comprehensive summary of the diverse strategies employed in multidimensional single-cell analysis, and particularly emphasizes the application of ultra-sensitive MS techniques, which provide new tools for single-cell nucleic acid analysis. It also highlights the discovery of functional nucleic acids, which offer novel alternatives for detecting metabolites and proteins at the single-cell level using amplification techniques. Additionally, the applications of these methods in life sciences, along with the prospects for multidimensional single-cell evaluation, are thoroughly discussed. It is anticipated that the continued evolution of multidimensional single-cell analysis will significantly advance the precision and depth of various research domains within life sciences.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"185 ","pages":"Article 118170"},"PeriodicalIF":11.8,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143164710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recent advances in the synthesis of covalent organic framework-based membranes and their applications for liquid-based separation
IF 11.8 1区 化学
Trends in Analytical Chemistry Pub Date : 2025-01-28 DOI: 10.1016/j.trac.2025.118167
Shaofeng Dong, Yuandi Xue, Songtao Li, Yajing Zhang, Shuyi Wang, Zian Lin
{"title":"Recent advances in the synthesis of covalent organic framework-based membranes and their applications for liquid-based separation","authors":"Shaofeng Dong,&nbsp;Yuandi Xue,&nbsp;Songtao Li,&nbsp;Yajing Zhang,&nbsp;Shuyi Wang,&nbsp;Zian Lin","doi":"10.1016/j.trac.2025.118167","DOIUrl":"10.1016/j.trac.2025.118167","url":null,"abstract":"<div><div>Membrane technology, as an efficient and eco-friendly separation means, has demonstrated substantial superiority in liquid-based separation and plays a pivotal role in environmental conservation and resource utilization. Traditional polymer-based membranes have long dominated the market for their simple preparation and low cost. But the disordered structure and irregular aperture of conventional amorphous membranes seriously hinder their performance. Recently, the emergence of covalent organic frameworks (COFs) has brought new vigor to membrane-based separation. COFs, connected by covalent bonds, have good crystallization and regular and uniform pore structure, thereby showcasing excellent stability and separation performance, becoming an ideal membrane material. In this paper, the synthesis and modification of COF-based membranes were reviewed, their inherent properties were also introduced. Besides, their applications in liquid-based separation were elaborated. Lastly, the challenges and focal points were discussed, aiming at offering inspirations for the development of COF-based membranes.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"185 ","pages":"Article 118167"},"PeriodicalIF":11.8,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143164713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Applications and prospects of micro/nanoelectrodes in single-cell imaging and electrochemical detection
IF 11.8 1区 化学
Trends in Analytical Chemistry Pub Date : 2025-01-28 DOI: 10.1016/j.trac.2025.118161
Xiaoyang Zhang, Ke Huang, Xiangdong Lai, Xiaohui Liu, Hui Jiang, Xuemei Wang
{"title":"Applications and prospects of micro/nanoelectrodes in single-cell imaging and electrochemical detection","authors":"Xiaoyang Zhang,&nbsp;Ke Huang,&nbsp;Xiangdong Lai,&nbsp;Xiaohui Liu,&nbsp;Hui Jiang,&nbsp;Xuemei Wang","doi":"10.1016/j.trac.2025.118161","DOIUrl":"10.1016/j.trac.2025.118161","url":null,"abstract":"<div><div>Single-cell electrochemical detection can reveal the underlying mechanisms that control cellular behaviors in diverse organisms. Compared to conventional electrochemical techniques, micro/nanoelectrodes are characterized by high temporal and spatial resolution, allowing precise and dynamic assessment of physiological and pathological changes in single-cell. In recent years, many micro/nano electrodes with high performance have been developed for the analysis of single-cell behaviors. Therefore, we have reviewed the application of micro/nanoelectrodes in single-cell electroanalysis. Firstly, we describe the classification, fabrication and characterization of micro/nanoelectrodes based on their features. Then, we highlight research utilizing these electrodes for in situ detection of cellular metabolite release, detection and imaging of cell membrane properties, and detection of intracellular components. In summary, we predict the future of micro/nanoelectrodes by evaluating electrode preparation methods, analytical capabilities, and associated electrochemical techniques, thereby providing valuable insights into the selection and optimization of micro/nanoelectrodes and promoting their application in single-cell behavior studies.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"185 ","pages":"Article 118161"},"PeriodicalIF":11.8,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143164717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Wearable MOF biosensors: A new frontier in real-time health monitoring
IF 11.8 1区 化学
Trends in Analytical Chemistry Pub Date : 2025-01-23 DOI: 10.1016/j.trac.2025.118156
Navid Rabiee
{"title":"Wearable MOF biosensors: A new frontier in real-time health monitoring","authors":"Navid Rabiee","doi":"10.1016/j.trac.2025.118156","DOIUrl":"10.1016/j.trac.2025.118156","url":null,"abstract":"<div><div>The development of wearable biosensors has revolutionized real-time health monitoring, enabling continuous and personalized insights into physiological states. Metal-organic frameworks (MOFs), with their unique properties including high surface area, tunability, and molecular selectivity, have emerged as promising materials for enhancing the sensitivity and specificity of wearable biosensors. This review explores recent advances in MOF-based wearable biosensors, highlighting their role in detecting key biomarkers for a range of health applications. This review discusses how MOFs improve analyte binding, signal transduction, and stability in physiological conditions, as well as the integration of these sensors with artificial intelligence (AI) and machine learning (ML) algorithms to enhance data processing and predictive analysis. Despite challenges such as ensuring biocompatibility, long-term stability, and scalability, wearable MOF biosensors represent a new frontier in personalized healthcare. Their potential to monitor multiple biomarkers simultaneously and provide continuous, accurate health assessments paves the way for future innovations in telemedicine and remote patient monitoring, ultimately contributing to improved healthcare outcomes and proactive disease management.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"184 ","pages":"Article 118156"},"PeriodicalIF":11.8,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum to “The standard addition method revisited” [TrAC Trends Anal. Chem. 89 (2017), 21-33]
IF 11.8 1区 化学
Trends in Analytical Chemistry Pub Date : 2025-01-23 DOI: 10.1016/j.trac.2025.118155
Jens E.T. Andersen
{"title":"Corrigendum to “The standard addition method revisited” [TrAC Trends Anal. Chem. 89 (2017), 21-33]","authors":"Jens E.T. Andersen","doi":"10.1016/j.trac.2025.118155","DOIUrl":"10.1016/j.trac.2025.118155","url":null,"abstract":"","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"184 ","pages":"Article 118155"},"PeriodicalIF":11.8,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spinel nanomaterials and their composites as extractors and sensors for heavy metals and other pollutants
IF 11.8 1区 化学
Trends in Analytical Chemistry Pub Date : 2025-01-23 DOI: 10.1016/j.trac.2025.118159
Hassan Elzain Hassan Ahmed , Mustafa Soylak
{"title":"Spinel nanomaterials and their composites as extractors and sensors for heavy metals and other pollutants","authors":"Hassan Elzain Hassan Ahmed ,&nbsp;Mustafa Soylak","doi":"10.1016/j.trac.2025.118159","DOIUrl":"10.1016/j.trac.2025.118159","url":null,"abstract":"<div><div>This extensive review deeply examined the current advancements in spinel metal oxides (SMOs) and their composites. The research studies the use of SMOs and their composites as multifunctional nanomaterials for the extraction and detection of heavy metals and other contaminants. Researchers have utilized SMOs, with their special crystal structure and unique physicochemical properties, as promising materials for sample preparation and detection applications. This study explores their synthesis, properties, sensing, adsorption, and practical applications, emphasizing their role as efficient adsorbents and sensors for heavy metals, pesticides, phenols, and organic dyes. We present a full description of the different SMO synthesis methods, including sol-gel, hydrothermal, and co-precipitation approaches, as well as a discussion of the aspects that influence their shape, stability, and other features. The study discusses the adsorption and sensing mechanisms that explain the higher efficacy of SMOs in the separation and detection of pollutants. Comparison analyses with traditional materials and techniques indicate the advantages of SMOs for sensitivity, selectivity, and reusability, providing a sustainable solution to environmental issues. This review presents schematic representations of synthesis methods and characterizations to help readers fully understand these materials. Furthermore, comparison tables and data reports give perspectives on SMO/SMO-based nanocomposites’ effectiveness across a range of sensing and extraction applications. This study also discusses the limitations and future aspects of SMOs, pointing out the need for more research to improve their performance and scalability. In general, this work serves as a valuable resource for comprehending the current applications of SMOs and their composites in the development of innovative nanomaterials as solutions for various environmental problems.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"184 ","pages":"Article 118159"},"PeriodicalIF":11.8,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Micro/nanoplastics in aquaponic systems: Sources, features and their effects on the immune system of fish
IF 11.8 1区 化学
Trends in Analytical Chemistry Pub Date : 2025-01-22 DOI: 10.1016/j.trac.2025.118158
Linyong Zhi , Zhen Li , Ruixue Li , Zeliang Su , Fang Chen , Guanglong Chen , Xiaohong Huang , Jun Wang
{"title":"Micro/nanoplastics in aquaponic systems: Sources, features and their effects on the immune system of fish","authors":"Linyong Zhi ,&nbsp;Zhen Li ,&nbsp;Ruixue Li ,&nbsp;Zeliang Su ,&nbsp;Fang Chen ,&nbsp;Guanglong Chen ,&nbsp;Xiaohong Huang ,&nbsp;Jun Wang","doi":"10.1016/j.trac.2025.118158","DOIUrl":"10.1016/j.trac.2025.118158","url":null,"abstract":"<div><div>Plastic debris in aquatic ecosystems undergoes weathering and degradation, breaking down into micro/nanoplastics (MNPs) that inflict physical damage or chemical toxicity upon ingestion by fish. The fish immune system exerts a key role in responding to and defending against pathogens and adverse environments, making it essential to assess the impact of MNPs on the fish immune system. Fish ingest MNPs through respiration, food intake, and bioaccumulation, which can impose a toxic burden on immune organs such as the gut, liver, kidneys, and spleen. MNPs exert toxic effects by destroying immune cells and altering gene expression. Notably, MNPs may synergize with environmental pollutants, including heavy metals, persistent organic pollutants, and pathogens, leading to more severe immune damage in fish. Additionally, the limitations of current research and future research directions are discussed, alongside feasible mitigation strategies for reducing plastic pollution.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"184 ","pages":"Article 118158"},"PeriodicalIF":11.8,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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