发布求助
文献互助 智能选刊 最新文献

Trends in Analytical Chemistry最新文献

筛选
英文 中文
Biosensor technologies: DNA-based approaches for foodborne pathogen detection 生物传感器技术：基于 DNA 的食源性病原体检测方法
IF 11.8 1区 化学
Trends in Analytical Chemistry Pub Date : 2024-08-22 DOI: 10.1016/j.trac.2024.117925
{"title":"Biosensor technologies: DNA-based approaches for foodborne pathogen detection","authors":"","doi":"10.1016/j.trac.2024.117925","DOIUrl":"10.1016/j.trac.2024.117925","url":null,"abstract":"<div><p>Foodborne diseases are a global concern due to their high impact on morbidity, and mortality worldwide. The traditional method of bacterial detection is both time-consuming and labor-intensive. Alternative methods, such as immunoassays and polymerase chain reactions, have limited applicability due to the need for an enrichment process and expensive equipment. DNA-based biosensors have gained interest in the field of detection, due to their high rapidity, high sensitivity, and high specificity, which provides a promising technology for bacterial detection. To fabricate DNA-based biosensors, the immobilization of DNA probes on electrodes is a crucial process. This review delves into the three techniques of DNA probe immobilization, discussing their respective advantages and disadvantages. Furthermore, recent advancements in DNA-based biosensors are explored. The integration of advanced molecular techniques such as DNA nanostructures, DNA walkers, and the CRISPR-Cas system with DNA-based biosensors for foodborne pathogens is also discussed in this work.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":null,"pages":null},"PeriodicalIF":11.8,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142136279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
“New sorbents for sample pretreatment: Development and applications” "用于样品预处理的新型吸附剂：开发与应用"
IF 11.8 1区 化学
Trends in Analytical Chemistry Pub Date : 2024-08-22 DOI: 10.1016/j.trac.2024.117924
{"title":"“New sorbents for sample pretreatment: Development and applications”","authors":"","doi":"10.1016/j.trac.2024.117924","DOIUrl":"10.1016/j.trac.2024.117924","url":null,"abstract":"<div><p>Sample preparation prior to instrumental analysis is a key step to achieve high quality qualitative/quantitative analytes determinations present in complex samples. Development of pretreatment methods, with the aim of preconcentrate analyte(s) of interest or isolating them from their matrices which may contain possible interferents, has been a continuous task over the years. Multiple goals are pursued to obtain improved pretreatment methods, such as low sample consumption, specificity or selectivity, high throughput, simplicity, robustness, as well as reducing economic costs. In recent years, sample pretreatment has also focused on reducing environmental pollution and enabling miniaturization and automation. Therefore, classic methods of liquid-liquid extraction and liquid-solid extraction are being replaced at a significant rate by miniaturized techniques such as single-drop microextraction, dispersive liquid-liquid microextraction, solid-phase microextraction, dispersive solid phase microextraction, microextraction with packed sorbents, among others, using a wide variety of sorbents, including monolithic polymers, metal-organic frameworks, carbon-based and magnetic nanomaterials. This review summarizes the most relevant progress achieved in the last five years on advanced sorbent materials for sample preparation. In addition, most employed miniaturized solid phase extraction techniques and their applications to extraction of organic compounds in complex matrices were considered. Advantages and disadvantages, analytical performance, as well as their underlying principles and environmental benefits are discussed. Several applications of these modern materials in sample preparation methods are shown and future trends in the development of new sorbents used are proposed.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":null,"pages":null},"PeriodicalIF":11.8,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142049142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Near infrared quantum dots for biosensing and bioimaging 用于生物传感和生物成像的近红外量子点
IF 11.8 1区 化学
Trends in Analytical Chemistry Pub Date : 2024-08-20 DOI: 10.1016/j.trac.2024.117922
{"title":"Near infrared quantum dots for biosensing and bioimaging","authors":"","doi":"10.1016/j.trac.2024.117922","DOIUrl":"10.1016/j.trac.2024.117922","url":null,"abstract":"<div><p>Quantum dots (QDs) possess unique optoelectronic properties, which make them very attractive to be used as optical probes in biosensing and bioimaging applications. The strong absorbance and light scattering of biological compounds like tissue and blood in the visible range pose a problem. However, if optical probes emitting in the near-infrared (NIR) range are used, scattering, absorption, and autofluorescence of biological components are strongly reduced. This allows for an increased light penetration depth and higher spatial and temporal resolution for the investigation of biological processes. The synthesis and application of NIR emitting QDs is a fast-growing research field and the benefits of using QDs were demonstrated for a variety of applications, such as photoelectrochemical biosensor, <em>in vivo</em> vascular imaging, and fluorescence-guided surgery. This article reviews the state-of-the-art developments in the preparation of NIR/IR QDs and highlights the latest research about their utilization in biosensing and bioimaging applications.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":null,"pages":null},"PeriodicalIF":11.8,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0165993624004059/pdfft?md5=caf184609ab90de016cf36ab9afb8d27&pid=1-s2.0-S0165993624004059-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142058215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advances in monitoring pharmaceuticals in an aquatic environment: Greenness assessment of analytical procedures 监测水生环境中药物的进展：分析程序的绿色评估
IF 11.8 1区 化学
Trends in Analytical Chemistry Pub Date : 2024-08-20 DOI: 10.1016/j.trac.2024.117921
{"title":"Advances in monitoring pharmaceuticals in an aquatic environment: Greenness assessment of analytical procedures","authors":"","doi":"10.1016/j.trac.2024.117921","DOIUrl":"10.1016/j.trac.2024.117921","url":null,"abstract":"<div><p>Pharmaceutical residues in the aquatic environment are of particular interest because, despite their presence in low concentrations, their adverse impact on both human health and entire ecosystems has been proven. Classic methods used in water monitoring require large amounts of organic solvents and generate large amounts of waste. Most of them are volatile and harmful to the environment. With the increase in public awareness, more and more attention is being paid to the development of green analytical procedures with less impact on the environment and workers. Moreover, metric tools have been developed for the evaluation of the greenness of proposed methods. This review presents and describes the advances of greening analytical procedures used in pharmaceuticals monitoring in an aquatic environment. The latest developments in eco-friendly sampling and sample processing strategies as well as green instrumental techniques for the determination of medicines in water were discussed.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":null,"pages":null},"PeriodicalIF":11.8,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142039640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bridging the gap: Advanced biosensor technologies for early-stage oral cancer diagnosis based on biomarker detection 缩小差距：基于生物标记检测的早期口腔癌诊断先进生物传感器技术
IF 11.8 1区 化学
Trends in Analytical Chemistry Pub Date : 2024-08-20 DOI: 10.1016/j.trac.2024.117923
{"title":"Bridging the gap: Advanced biosensor technologies for early-stage oral cancer diagnosis based on biomarker detection","authors":"","doi":"10.1016/j.trac.2024.117923","DOIUrl":"10.1016/j.trac.2024.117923","url":null,"abstract":"<div><p>This paper examines the recent strides in biosensor technologies aimed at revolutionizing the early detection of oral cancer. Early diagnosis is pivotal in enhancing treatment efficacy and patient survival rates. This review provides an in-depth analysis of diverse biosensing methodologies, encompassing electrochemical, optical, and mass-based approaches. Incorporating nanomaterials and biomarkers are explored for heightened sensitivity and specificity in oral cancer detection. The discussion critically evaluates the challenges in current diagnostic methods for oral cancer and underscores the potential of advanced biosensors in overcoming these limitations. Emphasis is placed on the amalgamation of artificial intelligence and machine learning algorithms for robust data analysis, further refining diagnostic accuracy. This review highlights the transformative impact of advanced biosensor technologies on early-stage oral cancer diagnosis. Integrating innovative sensing strategies addresses current diagnostic challenges and holds the potential to minimize invasiveness and facilitate timely interventions, significantly improving patient outcomes in the realm of oral cancer.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":null,"pages":null},"PeriodicalIF":11.8,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142044571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A reproducibility crisis for clinical metabolomics studies 临床代谢组学研究的再现性危机
IF 11.8 1区 化学
Trends in Analytical Chemistry Pub Date : 2024-08-19 DOI: 10.1016/j.trac.2024.117918
{"title":"A reproducibility crisis for clinical metabolomics studies","authors":"","doi":"10.1016/j.trac.2024.117918","DOIUrl":"10.1016/j.trac.2024.117918","url":null,"abstract":"<div><p>Cancer is a leading cause of world-wide death and a major subject of clinical studies focused on the identification of new diagnostic tools. An in-depth meta-analysis of 244 clinical metabolomics studies of human serum samples highlights a reproducibility crisis. A total of 2,206 unique metabolites were reported as statistically significant across the 244 studies, but 72% (1,582) of these metabolites were identified by only one study. Further analysis shows a random disparate disagreement in reported directions of metabolite concentration changes when detected by multiple studies. Statistical models revealed that 1,867 of the 2,206 metabolites (85%) are simply statistical noise. Only 3–12% of these metabolites reach the threshold of statistical significance for a specific cancer type. Our findings demonstrate the absence of a detectable metabolic response to cancer and provide evidence of a serious need by the metabolomics community to establish widely accepted best practices to improve future outcomes.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":null,"pages":null},"PeriodicalIF":11.8,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142136281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recent advances in liquid crystal droplet-based biosensors 液晶液滴生物传感器的最新进展
IF 11.8 1区 化学
Trends in Analytical Chemistry Pub Date : 2024-08-18 DOI: 10.1016/j.trac.2024.117920
{"title":"Recent advances in liquid crystal droplet-based biosensors","authors":"","doi":"10.1016/j.trac.2024.117920","DOIUrl":"10.1016/j.trac.2024.117920","url":null,"abstract":"<div><p>Liquid crystals (LCs), as stimuli-responsive soft materials with optical anisotropy, have shown great potential in the development of LC-based photonic devices. In recent years, the intriguing optical properties of LCs have aroused enormous interest in biosensing fields. LC droplets have received particular attention recently due to their large surface area-to-volume ratio and rich topographic information. Herein, the recent advances of LC droplet-based biosensors, including nematic LC, cholesteric LC and whispering gallery mode-based LC droplets, are introduced. The optical properties, detection principles, as well as fabrication methods of the three types of LC droplets are summarized. Representative examples of LC droplet-biosensors, with an emphasis on the design strategies of the biosensing interfaces for various biological analytes, are then discussed in detail. Finally, perspectives on future challenges and opportunities of LC droplet-based biosensors are discussed.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":null,"pages":null},"PeriodicalIF":11.8,"publicationDate":"2024-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142039639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Selective detection enabled by terahertz spectroscopy and plasmonics: Principles and implementations 利用太赫兹光谱学和等离子体学实现选择性检测：原理与实施
IF 11.8 1区 化学
Trends in Analytical Chemistry Pub Date : 2024-08-17 DOI: 10.1016/j.trac.2024.117917
{"title":"Selective detection enabled by terahertz spectroscopy and plasmonics: Principles and implementations","authors":"","doi":"10.1016/j.trac.2024.117917","DOIUrl":"10.1016/j.trac.2024.117917","url":null,"abstract":"<div><p>Speedy and selective detection of sensing targets is of great interest to researchers from diverse fields. Dominated by excitations of intramolecular and intermolecular vibrations, the emerging terahertz (THz) spectroscopy offers both molecular fingerprint information and biosensing abilities, which is excellent for speedy and selective sensing applications. In this review, we focus on THz selective sensing principles and introduce three frequently utilized methods enabled by THz fingerprints, the interaction between THz absorption of molecules and plasmonic resonances, and THz metamaterial biosensors. The recent progress of THz selective sensing implementations including detections of gas molecules, solid molecules, protein, nucleic acid, cells, and viruses are also summarized. We note that current THz sensing research is multidisciplinary and has led cross-disciplinary collaborations between physics and bioscience. The acceleration of THz selective sensing will realize plenty practical THz applications and achieve outstanding improvements.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":null,"pages":null},"PeriodicalIF":11.8,"publicationDate":"2024-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142039606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fluorescent metal nanoclusters for explosive detection: A review 用于爆炸物检测的荧光金属纳米团簇：综述
IF 11.8 1区 化学
Trends in Analytical Chemistry Pub Date : 2024-08-17 DOI: 10.1016/j.trac.2024.117919
{"title":"Fluorescent metal nanoclusters for explosive detection: A review","authors":"","doi":"10.1016/j.trac.2024.117919","DOIUrl":"10.1016/j.trac.2024.117919","url":null,"abstract":"<div><p>Explosives pose significant threats to global safety and cause widespread environmental concerns, thus the development of rapid and reliable detection methods for explosives is highly important. In recent years, metal nanoclusters (MNCs) have garnered considerable attention due to their ultrasmall size, well-defined structure, distinct fluorescent properties and tailorable surface chemistry, making them promising for the design of robust fluorescent explosive sensors. This review first summarizes the sensing mechanisms based on MNCs for explosive detection, and then provides an overview of sensing strategies and detection performance utilizing three primary types of MNCs (gold, silver, and copper NCs). Finally, current challenges and future development prospects of MNC-based sensors for explosive detection are discussed.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":null,"pages":null},"PeriodicalIF":11.8,"publicationDate":"2024-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142011990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Focusing on the infrared region: A critical review of infrared-related materials and techniques for the development, imaging, and analysis of latent fingerprints 聚焦红外区域：对用于潜在指纹的开发、成像和分析的红外相关材料和技术的严格审查
IF 11.8 1区 化学
Trends in Analytical Chemistry Pub Date : 2024-08-15 DOI: 10.1016/j.trac.2024.117915
{"title":"Focusing on the infrared region: A critical review of infrared-related materials and techniques for the development, imaging, and analysis of latent fingerprints","authors":"","doi":"10.1016/j.trac.2024.117915","DOIUrl":"10.1016/j.trac.2024.117915","url":null,"abstract":"<div><p>It is a fundamental task in forensic science to utilize latent fingerprints to identify individuals who may be involved in a crime. Over the past two decades, owing to multiple benefits of using infrared-related materials and techniques in the development, imaging, and analysis of latent fingerprints, numerous studies have been performed to solve substantial challenges faced by conventional methods in this area. In this review, to appeal the communities in related research fields and to provide the wider scientific community with broad implications, comprehensive review and detailed discussion of the infrared-related materials and techniques are presented according to the imaging modes applied to capture and analyze fingerprints, namely, NIR to VIS mode, UV-VIS to NIR mode, NIR to NIR mode, and IR absorption/reflection mode. Finally, based on the overview of recent progress, three main aspects that require to be explored and improved in the research of this field are proposed.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":null,"pages":null},"PeriodicalIF":11.8,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142039638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信