Lab on a Chip最新文献

Correction: A piezoelectric ultrasound-assisted microjetting platform for high-throughput intracellular delivery

IF 6.1 2区工程技术

Lab on a Chip Pub Date : 2026-10-21 DOI: 10.1039/d6lc90094a

Jianfeng Chen,Ke Li,Yichuan Di,Feifan Hu,Yaqi Nie,Xiaoshan Jin,Xiaoxiao Chen,Mengxian Zhang,Meirong Yi

引用次数: 0

Data-Efficient Inverse Design of Inlet Boundary Conditions in Hexagonal Microfluidic Arrays for Concentration Generation

IF 6.1 2区工程技术

Lab on a Chip Pub Date : 2026-10-21 DOI: 10.1039/d6lc00590j

Xingwang An,Longfei Yu,Guoqing Hu

{"title":"Data-Efficient Inverse Design of Inlet Boundary Conditions in Hexagonal Microfluidic Arrays for Concentration Generation","authors":"Xingwang An,Longfei Yu,Guoqing Hu","doi":"10.1039/d6lc00590j","DOIUrl":"https://doi.org/10.1039/d6lc00590j","url":null,"abstract":"Complex concentration fields in microfluidic arrays are often designed through repeated forward simulation or experiment, which becomes inefficient when a prescribed target field is given in advance. Here, we present a Bayesian optimization framework for the inverse design of inlet boundary conditions in close-packed hexagonal microfluidic arrays. The framework combines Gaussian process regression with a Matérn 2.5 kernel and a log-scale loss function to mitigate the vanishing sensitivity in low-error regimes. To address user-defined target fields that may not be fully physically attainable due to diffusion-limited transport, we introduce an adaptive constraint optimization strategy that progressively shifts the search toward physically feasible regions of the design space. For larger arrays, we further incorporate a sparse sampling strategy motivated by the low-dimensional structure of the concentration field with respect to the 12 inlet boundary-condition variables. The framework was evaluated on hexagonal arrays containing 60 and 468 chambers. In the 60-chamber self-consistency test, the inverse solver recovered target fields with high accuracy. Across nine additional physically generated targets, the 60-chamber model achieved a median R2 of 0.9572. For empirically prescribed targets, the adaptive constraint strategy improved convergence toward physically realizable solutions. In the 468-chamber array, optimizing 54 representative chambers (corresponding to ≈ 11.5% of the total) recovered the dominant spatial structure of the full concentration field, yielding an R2 of 0.8457 when evaluated against all 468 chambers. These results show that Bayesian inverse design can provide a practical and data-efficient route for concentration-field programming in large microfluidic networks and support the automated generation of complex chemical microenvironments.","PeriodicalId":85,"journal":{"name":"Lab on a Chip","volume":"14 1","pages":""},"PeriodicalIF":6.1,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149225835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microdroplet hemagglutination assay for virus-like particle (VLP) quantification

IF 6.1 2区工程技术

Lab on a Chip Pub Date : 2026-10-20 DOI: 10.1039/d6lc00499g

Merve Marcali,Caglar Elbuken,Eduardo Ramirez,Madhuja Chakraborty,Marc G. Aucoin,Carolyn L. Ren

{"title":"Microdroplet hemagglutination assay for virus-like particle (VLP) quantification","authors":"Merve Marcali,Caglar Elbuken,Eduardo Ramirez,Madhuja Chakraborty,Marc G. Aucoin,Carolyn L. Ren","doi":"10.1039/d6lc00499g","DOIUrl":"https://doi.org/10.1039/d6lc00499g","url":null,"abstract":"Rapid and sensitive assessment of viral hemagglutinating activity is important for vaccine development and viral analysis, while conventional hemagglutination (HA) assays are limited by long processing times, high reagent consumption, and subjective endpoint interpretation. Here we present a droplet microfluidic platform that miniaturizes and automates hemagglutination-based analysis of influenza virus-like particles (VLPs). The system integrates a standard T-junction droplet generator and serpentine mixing channels to enable controlled encapsulation and rapid in-droplet mixing of VLPs and red blood cells (RBCs). Compared with the conventional static HA assay, the microfluidic platform provides an operational aggregate-size endpoint within approximately 60 s under the conditions tested, while substantially reducing sample consumption. System performance was systematically evaluated across varying RBC concentrations, RBC/VLP ratios, droplet sizes, and RBC sample freshness. The platform detected hemagglutinating activity at an eightfold greater sample dilution than the conventional well-plate assay under the conditions tested. This improved sensitivity enables assessment of hemagglutinating activity in low-activity downstream fractions that may fall below the detection limit of conventional HA assays, potentially supporting the monitoring of HA-active material and its recovery during VLP-based vaccine production. These results establish a basis for a rapid, low-volume, and scalable microfluidic platform for assessing VLP hemagglutinating activity and vaccine bioprocess monitoring.","PeriodicalId":85,"journal":{"name":"Lab on a Chip","volume":"63 1","pages":""},"PeriodicalIF":6.1,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149225832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel 3D-printed microfluidic chip for automated real-time multi-route in-vivo nanoplastics toxicity testing

IF 6.1 2区工程技术

Lab on a Chip Pub Date : 2026-10-20 DOI: 10.1039/d5lc01057h

Preyojon Dey,Terence M. Bradley,Alicia Boymelgreen

{"title":"Novel 3D-printed microfluidic chip for automated real-time multi-route in-vivo nanoplastics toxicity testing","authors":"Preyojon Dey,Terence M. Bradley,Alicia Boymelgreen","doi":"10.1039/d5lc01057h","DOIUrl":"https://doi.org/10.1039/d5lc01057h","url":null,"abstract":"Plastics are one of the most pervasive pollutants in marine environments, with smaller-sized plastics, such as nanoplastics (NPLs), posing significant but understudied threats to marine organisms. Traditional bulk and end-point testing methods are limited in their ability to provide real-time, in-situ assessments of nanotoxicity, hindering a comprehensive mechanistic understanding of their impacts. In this study, we present a fully 3D-printed, automated microfluidic chip designed for multi-route in vivo nanotoxicity testing, which addresses the limitations of conventional methods by offering automated and dynamic exposure conditions alongside real-time monitoring through photography and oxygen sensing. Additionally, this platform simplifies the fabrication process, avoiding the time-consuming soft-lithography typically used for microfluidic chips. As a proof of concept, the chip was used to assess nanotoxicity in model marine organisms across different trophic levels: Artemia franciscana (instar II and III stages) and a mixture of five microalgae. Polystyrene nanoplastics, one of the most prevalent plastics in marine environments, were used as the model NPLs and tested in two exposure routes: waterborne and foodborne. The results revealed distinct uptake dynamics; bioaccumulation decreased over time in waterborne exposure but increased in foodborne exposure. Oxygen consumption was elevated in both species during waterborne exposure, compared to the control, while no significant differences were observed in the foodborne group, likely due to delayed interaction with NPLs during algae digestion and the inactivity or mortality of nauplii at the end of the experimental period.","PeriodicalId":85,"journal":{"name":"Lab on a Chip","volume":"62 1","pages":""},"PeriodicalIF":6.1,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149225816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Engineering a 3D Microfluidic Platform to Model Neuroimmune Interactions in Periodontal Inflammation 设计一个三维微流控平台来模拟牙周炎症中的神经免疫相互作用

IF 6.1 2区工程技术

Lab on a Chip Pub Date : 2026-10-19 DOI: 10.1039/d6lc00687f

Nandita Menon,Aiman Ali,Annie Shrestha,Anil Kishen

{"title":"Engineering a 3D Microfluidic Platform to Model Neuroimmune Interactions in Periodontal Inflammation","authors":"Nandita Menon,Aiman Ali,Annie Shrestha,Anil Kishen","doi":"10.1039/d6lc00687f","DOIUrl":"https://doi.org/10.1039/d6lc00687f","url":null,"abstract":"Neuroimmune interactions play a critical role in the progression of periodontal inflammatory diseases such as Apical Periodontitis (AP), highlighting the need for in vitro systems capable of capturing their multicellular complexity within physiologically relevant microenvironments. Here, we present a novel 3D tri-culture microfluidic platform (3TMP) that integrates human periodontal ligament cells (PDLCs) and macrophages (MQs) in collagen 1 matrix, and neuron-like cells (NLCs) in Matrigel to investigate coupled immune, stromal, and neuronal signaling. Lipopolysaccharide (LPS) stimulation induced temporally distinct inflammatory responses within the device. These responses were notably shaped by the presence of NLCs, underscoring the contribution of bidirectional neuroimmune crosstalk. At 3h, NLCs were associated with reduced CD80/CD206, STAT1/STAT3, TNF-α, IL-1β, IL-8, and Substance P (SP), alongside elevated prostaglandin E2 (PGE2) and Calcitonin Gene-Related Peptide (CGRP), indicating an early attenuated inflammatory profile. By 24h, this shifted towards increased STAT1/STAT6, TNF-α, IL-6, and IL-8, with further elevations in PGE2 accompanied by increased CGRP, IL-10, and TGF-β1, consistent with sustained inflammatory signaling alongside emerging counter-regulatory responses. At the neuronal level, TRP channel dynamics revealed reduced TRPV1 expression despite elevated PGE2, consistent with receptor desensitization, alongside increased TRPA1 expression in the context of inflammatory cytokine signaling. Validation using a mouse model of AP confirmed that cytokine profiles, neuropeptide expression, and TRP channel patterns observed in the 3TMP reproduce key features of in vivo disease. This 3TMP platform provides a human cell-based, physiologically relevant platform for investigating neuroimmune mechanisms and evaluating therapeutic responses in periodontal inflammation.","PeriodicalId":85,"journal":{"name":"Lab on a Chip","volume":"42 1","pages":""},"PeriodicalIF":6.1,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149218144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Low-order lateral transducer modes enabling millimeter-scale acoustofluidics. 低阶横向换能器模式实现毫米级声流体。

IF 6.3 2区工程技术

Lab on a Chip Pub Date : 2026-10-19 DOI: 10.1039/d6lc00493h

Andreas Fuchsluger, Thomas Voglhuber-Brunnmaier, Nikolai Andrianov, Bernhard Jakoby

{"title":"Low-order lateral transducer modes enabling millimeter-scale acoustofluidics.","authors":"Andreas Fuchsluger, Thomas Voglhuber-Brunnmaier, Nikolai Andrianov, Bernhard Jakoby","doi":"10.1039/d6lc00493h","DOIUrl":"https://doi.org/10.1039/d6lc00493h","url":null,"abstract":"Bulk acoustic wave devices commonly use thickness modes of piezoelectric plates to generate standing waves in microfluidic cavities, typically at 2 MHz and above, with corresponding wavelengths well below the millimeter scale. However, handling larger mesoscopic objects-such as organoids and small model organisms, including nematodes-requires millimeter-scale fluidic structures. Single-node alignment in such cavities demands half-wavelength fields and thus sub-megahertz actuation. Conventional sub-megahertz operation requires thicker piezoelectric plates, resulting in bulky designs or requiring plate thicknesses that are not readily available commercially. Here, we demonstrate a practical yet elegant alternative based on a low-order lateral extensional mode of the transducer plate. Compared with thickness-mode devices of identical footprint, the approach lowers the operating frequency approximately fourfold and increases the channel cross section sixteenfold. Unlike typical Lamb-wave devices based on multiwavelength propagation at several megahertz and above, the present approach uses a low-order standing S0 Lamb mode. The numerically optimized devices operate at approximately 540 kHz and achieve rapid particle focusing in millimeter-wide channels, while vibrometry confirms the predicted vibration patterns and admittance measurements show that the lateral resonance is well preserved upon chip loading, with only a small, predictable shift in resonance frequency. The present study focuses on modal characterization and particle-focusing validation. Practical limitations include heating at high actuation voltages and the finite lifetime of the liquid acoustic coupling layer.","PeriodicalId":85,"journal":{"name":"Lab on a Chip","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149219701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Three-dimensional imaging flow cytometry: current trends and future perspectives. 三维成像流式细胞术：当前趋势和未来展望。

IF 6.3 2区工程技术

Lab on a Chip Pub Date : 2026-10-16 DOI: 10.1039/d6lc00580b

Xuanwen Hua, Biagio Mandracchia, Zhi Ling, Kidan Tadesse, Hajun Yoo, Jin Yan, Ho Wai Howard Lee, Shu Jia

{"title":"Three-dimensional imaging flow cytometry: current trends and future perspectives.","authors":"Xuanwen Hua, Biagio Mandracchia, Zhi Ling, Kidan Tadesse, Hajun Yoo, Jin Yan, Ho Wai Howard Lee, Shu Jia","doi":"10.1039/d6lc00580b","DOIUrl":"10.1039/d6lc00580b","url":null,"abstract":"Imaging flow cytometry (IFC) combines microscopic techniques and flow cytometry, enabling high-throughput, population-scale single-cell analysis with rich spatial detail and high molecular specificity. To date, most established IFC platforms are fundamentally built around 2D imaging, which is inherently limited in its ability to capture the complex 3D morphology, intracellular organization, and spatially distributed molecular features of single cells under flow. Driven by the growing demand for volumetric cellular information, IFC has progressively evolved from 2D imaging toward 3D imaging flow cytometry through a variety of optical and computational strategies. Existing 3D IFC approaches typically fall into scanning-based and non-scanning modalities, depending on whether volumetric information is assembled through sequential or parallel acquisition, with each paradigm offering complementary strengths in 3D imaging performance and cytometric throughput. Here, we systematically compare the underlying principles and performance characteristics of the most representative scanning-based and non-scanning 3D IFC technologies and discuss current challenges and future opportunities to advance volumetric cytometric analysis in biomedical and translational research.","PeriodicalId":85,"journal":{"name":"Lab on a Chip","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13673952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149190219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cell-laden hydrogel microspheres as functional 3D cellular units. 作为功能三维细胞单元的载细胞水凝胶微球。

IF 6.3 2区工程技术

Lab on a Chip Pub Date : 2026-10-16 DOI: 10.1039/d6lc00603e

Wenjun Liao, Ling Lin, Yang Song, Jin-Ming Lin

{"title":"Cell-laden hydrogel microspheres as functional 3D cellular units.","authors":"Wenjun Liao, Ling Lin, Yang Song, Jin-Ming Lin","doi":"10.1039/d6lc00603e","DOIUrl":"https://doi.org/10.1039/d6lc00603e","url":null,"abstract":"Engineering three-dimensional cellular systems with controlled size, matrix composition and cellular organization is central to disease modelling, drug evaluation and regenerative medicine. In this context, cell-laden hydrogel microspheres have emerged as a platform for constructing microscale living units. Their structure facilitates local cell-matrix interactions and cell-cell communication, while the hydrogel phase provides a tunable microenvironment for cell culture and function. Droplet microfluidics offers a powerful route to produce these microspheres with defined size, composition, architecture and cellular input, allowing fabrication parameters to be linked directly with biological outcomes. In this review, we focus on how droplet microfluidics, hydrogel matrix design and cellular organization converge to transform cell encapsulation into the construction of functional 3D cellular units. We outline the principles of microsphere fabrication, including droplet generation, gelation and post-generation recovery, and discuss how hydrogel matrices regulate processability, bioactivity and reproducibility. We then examine how cell loading, spatial architecture and organoid-centered organization determine microsphere function. Finally, we discuss applications in bioanalysis, drug testing, therapeutic delivery and tissue assembly, and highlight key challenges in cytocompatible processing, recovery, reproducibility, standardization and functional validation. This review aims to provide design principles for transforming cell encapsulation into interpretable and deployable microscale living systems.","PeriodicalId":85,"journal":{"name":"Lab on a Chip","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149190274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A rapid point-of-care detection system for OVA-specific IgG and IgE utilizing a rotational SlipChip 一种利用旋转滑片快速检测ova特异性IgG和IgE的即时检测系统

IF 6.1 2区工程技术

Lab on a Chip Pub Date : 2026-10-14 DOI: 10.1039/d6lc00822d

Honglin Lu,Yifan Jia,Jianxia Wang,Zixuan Song,Di Wu,Bei Wang,Wenxin Zhang,Fang Yang

{"title":"A rapid point-of-care detection system for OVA-specific IgG and IgE utilizing a rotational SlipChip","authors":"Honglin Lu,Yifan Jia,Jianxia Wang,Zixuan Song,Di Wu,Bei Wang,Wenxin Zhang,Fang Yang","doi":"10.1039/d6lc00822d","DOIUrl":"https://doi.org/10.1039/d6lc00822d","url":null,"abstract":"Allergic diseases affect approximately 22% of the global population. Rapid and accurate identification of causative allergens is essential for enabling timely clinical intervention and preventing re-exposure. Current clinical approaches for in vivo allergen diagnosis often involve risks associated with direct allergen exposure, while many existing in vitro diagnostic methods remain labor-intensive, time-consuming, and technically demanding. For example, the basophil activation test requires sophisticated instrumentation and specialized operational expertise. Therefore, there is an urgent need for a convenient, rapid, sensitive, and easily assembled platform for reliable in vitro allergen diagnosis while reducing reliance on sample pretreatment, auxiliary instrumentation, and external control systems. In this study, a disc-shaped microfluidic device, termed the Relative Rotation SlipChip (rr-SlipChip), was developed. Unlike conventional SlipChip platforms that depend on precise microstructural alignment, the rr-SlipChip employs radial alignment and step-by-step rotation to enable convenient configuration of loading pathways for multiple immunoreagents. In addition, the reagent pathways are completely isolated from one another, thereby minimizing the risk of cross-contamination. Using a single rotary pneumatic control channel combined with a simple sliding operation, the proposed device enables immunoassays to be completed within approximately 25–37 min. The rr-SlipChip achieves favorable analytical sensitivity, with limits of detection of 0.614 ng/mL for sIgG and 0.689 ng/mL for sIgE. Therefore, the rr-SlipChip introduces a new rotational sliding microfluidic architecture distinct from conventional SlipChip designs, providing a novel platform for rapid, sensitive, continuous, and scalable in vitro allergen diagnosis with significant potential for point-of-care testing (POCT) and accessible precision allergy management.","PeriodicalId":85,"journal":{"name":"Lab on a Chip","volume":"232 1","pages":""},"PeriodicalIF":6.1,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149152792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrode-Free Three-Dimensional Droplet Manipulation on Open Superhydrophobic Surfaces via Triboelectric Charging 开放超疏水表面上无电极三维液滴的摩擦电荷操纵

IF 6.1 2区工程技术

Lab on a Chip Pub Date : 2026-10-13 DOI: 10.1039/d6lc00679e

Yu Chia Chen,Yuan Hsuen Chou,Cheng Han Yu,Kuan Ting Chen,Chin-Chi Hsu,Tsai Fu Chung,Jiann Shieh

{"title":"Electrode-Free Three-Dimensional Droplet Manipulation on Open Superhydrophobic Surfaces via Triboelectric Charging","authors":"Yu Chia Chen,Yuan Hsuen Chou,Cheng Han Yu,Kuan Ting Chen,Chin-Chi Hsu,Tsai Fu Chung,Jiann Shieh","doi":"10.1039/d6lc00679e","DOIUrl":"https://doi.org/10.1039/d6lc00679e","url":null,"abstract":"Open-surface microfluidics provides direct access to liquids and offers unique advantages for chemical and biological processing, yet most existing platforms remain limited to individual manipulation functions or planar droplet transport. Here, we present an electrode-free programmable open-surface liquid-handling platform that integrates two-dimensional droplet transport with reliable airborne inter-substrate transfer through coordinated triboelectric electrostatic control. Localized charge printing on superhydrophobic glass creates programmable docking sites, while independently charged polytetrafluoroethylene (PTFE) controllers provide the electrostatic forces required for droplet capture, lifting, transport, and release, without embedded electrodes or continuous power supplies during operation. Integrated liquid-handling workflows were demonstrated using precipitation and colorimetric reactions, in which reacted droplets were picked up, transferred between independent substrates, and repositioned without visible liquid residue. Charge characterization, force analysis, and Maxwell stress tensor simulations show that switching of the electrostatic force balance governs transitions among mobile, captured, transported, and positioned droplet states. This work provides a general framework for programmable open-surface liquid handling through coordinated triboelectric electrostatic control.","PeriodicalId":85,"journal":{"name":"Lab on a Chip","volume":"9 1","pages":""},"PeriodicalIF":6.1,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149152036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0