Lab on a Chip最新文献_第10页

Semi-permeable membrane stabilized microfluidic plasma chip for continuous, tunable synthesis of sub-10 nm nanoparticles† 半透膜稳定微流控等离子体芯片，用于连续、可调合成10纳米以下的纳米颗粒。

IF 6.1 2区工程技术

Lab on a Chip Pub Date : 2025-05-23 DOI: 10.1039/D4LC00960F

Yu Liu, Xiaoyi Zeng, Hongjun Liu, Zhen Liu, Jiayan Zhuang, Chunhui Wu, Zijun Chen, Ji Tae Kim, Xin Tang and Xing Cheng

{"title":"Semi-permeable membrane stabilized microfluidic plasma chip for continuous, tunable synthesis of sub-10 nm nanoparticles†","authors":"Yu Liu, Xiaoyi Zeng, Hongjun Liu, Zhen Liu, Jiayan Zhuang, Chunhui Wu, Zijun Chen, Ji Tae Kim, Xin Tang and Xing Cheng","doi":"10.1039/D4LC00960F","DOIUrl":"10.1039/D4LC00960F","url":null,"abstract":"Atmospheric-pressure microplasma, characterized by its gaseous electrode containing tunable electrons and reactive species, can initiate reactions at the plasma/liquid interface. Integrating microplasma into a microfluidic chip can confine reactions to the microscale, enhancing uniformity and controllability. However, maintaining a stable gas/liquid interface in microchannels is inherently challenging due to Rayleigh–Plateau instability and perturbing pressure gradients. In this study, we designed a microfluidic plasma chip stabilized by a semi-permeable membrane for dielectric barrier discharge microplasma-assisted reactions. This hydrophobic porous membrane blocks liquid while allowing plasma to pass through, enabling independent biphasic control. Using gold nanoparticle synthesis as a model, we achieved a size ranging from 7.31 to 11.32 nm and a standard deviation of 1.8 nm, by detailed parameter study. The planar microplasma facilitates uniform, precise, and tunable reactions with short-lived and highly localized reactive species, making this approach suitable for challenging applications such as selective synthesis, pollutant degradation, and biomedical diagnostics.","PeriodicalId":85,"journal":{"name":"Lab on a Chip","volume":" 12","pages":" 2807-2815"},"PeriodicalIF":6.1,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144122342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Halochromism of rosolic acid: a pH-sensitive colorimetric dye combined with a smartphone technique for quantification of DNA in molecular diagnostics† 红果酸的变色：一种ph敏感比色染料结合智能手机技术用于分子诊断中的DNA定量。

IF 6.1 2区工程技术

Lab on a Chip Pub Date : 2025-05-22 DOI: 10.1039/D5LC00036J

Rajamanickam Sivakumar, Seo Yeon Park, Seung Kyun Park and Nae Yoon Lee

{"title":"Halochromism of rosolic acid: a pH-sensitive colorimetric dye combined with a smartphone technique for quantification of DNA in molecular diagnostics†","authors":"Rajamanickam Sivakumar, Seo Yeon Park, Seung Kyun Park and Nae Yoon Lee","doi":"10.1039/D5LC00036J","DOIUrl":"10.1039/D5LC00036J","url":null,"abstract":"Infectious foodborne pathogens are responsible for serious illnesses and socioeconomic losses worldwide, making early detection crucial to control excessive damage. Colorimetric loop-mediated isothermal amplification (LAMP) assays are a promising molecular detection technique that produces visually discernible color changes. However, factors such as color blindness, age, and sex can cause individuals to perceive colors differently, limiting the effectiveness of colorimetric assays. To address this, quantitative chromatic analysis was employed to reliably distinguish colors and analyze their digital images. We developed a red-green-blue (RGB) channel-based method using a smartphone application (color picker) to quantify colorimetric LAMP amplicons. Two genes, hlyA of Listeria monocytogenes (L. monocytogenes) and esp of Enterococcus faecium (E. faecium), were investigated using LAMP, the most widely used isothermal amplification technique. In this study, the pH indicator “rosolic acid (RA)” was introduced to identify weakly buffered LAMP amplicons based on the colorimetric shift from red to yellow, and the color was quantified using the R/(R + G + B) computation. The limit of quantification was as low as 10 fg μL−1 for L. monocytogenes and 1 fg μL−1 for E. faecium. Furthermore, the sensitivity of the proposed method was comparable to that of the traditional LAMP assay, which uses phenol red as a pH indicator. The practical application of the RA-based colorimetric LAMP assay was demonstrated by detecting the blaOXA-23-like carbapenemase gene of A. baumannii in saliva. Thus, the RA-mediated colorimetric LAMP assay, combined with the RGB-based quantitative approach using a smartphone APP, holds significant potential in molecular diagnostics for detecting foodborne pathogens.","PeriodicalId":85,"journal":{"name":"Lab on a Chip","volume":" 13","pages":" 3132-3140"},"PeriodicalIF":6.1,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144214403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mechanical regulation of nerve stem cells' multiple behaviors via GHz acoustic streaming† GHz声流对神经干细胞多种行为的机械调控。

IF 6.1 2区工程技术

Lab on a Chip Pub Date : 2025-05-22 DOI: 10.1039/D4LC00867G

Wenjun Li, Shenghui Kang, Wei Wei, Kai Yang, Xiaoyu Wu, Shan He, Zefang Wang, Wenlan Guo, Chen Sun, Wei Pang, Xuexin Duan and Yanyan Wang

{"title":"Mechanical regulation of nerve stem cells' multiple behaviors via GHz acoustic streaming†","authors":"Wenjun Li, Shenghui Kang, Wei Wei, Kai Yang, Xiaoyu Wu, Shan He, Zefang Wang, Wenlan Guo, Chen Sun, Wei Pang, Xuexin Duan and Yanyan Wang","doi":"10.1039/D4LC00867G","DOIUrl":"10.1039/D4LC00867G","url":null,"abstract":"Mechanical regulation of neural stem cell behavior is crucial for cellular transplantation and neural regenerative medicine. However, how neural stem cells perceive and respond to mechanical signals remains to be fully understood. In this study, a GHz bulk acoustic wave (BAW) resonator-based acoustic streaming (AS) regulatory system was designed, aiming to generate tunable shear forces on the cells for the controlled regulation of neuroectodermal (NE-4C) stem cell behavior. Results demonstrated that the gradient shear force produced by AS exhibited controlled regulation of cell movement, which could promote the transformation of the movement mode of cells from pseudopodia into bleb-driven movement rapidly. Then, AS was found to enhance cell motility by approximately 9.8 times compared to the unstimulated group. It was further proved that short-term AS stimulation could stably and efficiently promote both the parallel and vertical migration of cells. The number of vertically migrated cells in the 20 min AS-stimulated group was 10.9 times higher than that of the unstimulated group. Finally, the data showed that the proliferation multiple of cells could be controlled by changing the AS stimulation time and the input power of the device. In addition, AS stimulation could significantly accelerate the formation of neurite processes, ultimately leading to the production of neurons. To sum up, the AS shear force regulation system opened up the possibility of channel-less microfluidic systems, which could easily manipulate the cellular morphological changes. It provided a flexible tool for controllably regulating the migration, proliferation, and differentiation of neural stem cells, demonstrating its great potential in the fields of neural tissue engineering and regenerative medicine.","PeriodicalId":85,"journal":{"name":"Lab on a Chip","volume":" 13","pages":" 3156-3167"},"PeriodicalIF":6.1,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144214405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

3D-printed micro-pore evaporator for increasing concentration of analytes in aqueous solutions† 3d打印微孔蒸发器，用于增加水溶液中分析物的浓度。

IF 6.1 2区工程技术

Lab on a Chip Pub Date : 2025-05-20 DOI: 10.1039/D5LC00329F

Yufeng Su and Tanya Hutter

{"title":"3D-printed micro-pore evaporator for increasing concentration of analytes in aqueous solutions†","authors":"Yufeng Su and Tanya Hutter","doi":"10.1039/D5LC00329F","DOIUrl":"10.1039/D5LC00329F","url":null,"abstract":"To address the detection limit challenges of analytical instruments at low concentrations, this study explores the development of a concentrator, fabricated via micro-3D printing technology, relying on solvent evaporation through micro-pores. The operating temperature can be as low as room temperature, allowing for compatibility with biomolecules that are sensitive to high temperatures. Moreover, the device is suitable for processing small sample volumes ranging from hundreds to tens of microliters. There are three designs of the hydrophilic biocompatible polymer tube, each featuring micro-pores with diameters of 30, 50 and 70 μm, spaced at distances of 150, 250 and 350 μm, respectively. All designs have the same total length of 16 mm and identical contact surface area. The tube is surrounded by an outer tube for a sweeping gas at a flow between 20 and 100 mL min−1 for evaporation rate control. Theoretical calculations and experimental data were used to quantify device's performance and capabilities. Experiments conducted with deionized water and with aqueous glucose solutions demonstrate the device's capability to achieve up to a 10-fold concentration increase. The study also addresses potential issues such as analyte loss and the influence of various parameters like sweeping gas flow rates and liquid feeding rates on the concentration process. This work demonstrates the potential of the micro-3D printed device as a reliable and efficient method for sample concentration, critical for enhancing detection sensitivities for various applications such as bioassays and biosensors.","PeriodicalId":85,"journal":{"name":"Lab on a Chip","volume":" 13","pages":" 3141-3155"},"PeriodicalIF":6.1,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/lc/d5lc00329f?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144146152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A multi-channel chip enabled synchronized reciprocating-flow of fluid for rapid, simultaneous, multiplex detection of inflammatory markers† 多通道芯片使流体同步往复流动，用于快速、同时、多重检测炎症标志物。

IF 6.1 2区工程技术

Lab on a Chip Pub Date : 2025-05-20 DOI: 10.1039/D5LC00132C

Juanhua Li, Zihan Xiao, Tianyu Wu, Yiren Liu, Wenyong Zhang, Cuiping Zhou, Yanqiong Su, Hongrui Liang, Donglin Cao and Jianhua Zhou

{"title":"A multi-channel chip enabled synchronized reciprocating-flow of fluid for rapid, simultaneous, multiplex detection of inflammatory markers†","authors":"Juanhua Li, Zihan Xiao, Tianyu Wu, Yiren Liu, Wenyong Zhang, Cuiping Zhou, Yanqiong Su, Hongrui Liang, Donglin Cao and Jianhua Zhou","doi":"10.1039/D5LC00132C","DOIUrl":"10.1039/D5LC00132C","url":null,"abstract":"Infections are common in daily life and can lead to various acute diseases with complex symptoms. Rapid and accurate detection of multiple inflammatory markers using multi-channel microfluidic chips provides important guidance for controlling the development of infections. However, current fluid control methods for multi-channel microfluidic chips typically involve controlling the liquid in each channel separately and successively, which increases the complexity of control operations and the detection time. Here, we proposed a circularly-aligned parallel channel chip (CAPC chip) with multiple channels and used this chip for the rapid, simultaneous detection of four inflammatory markers. We implemented the integrated fluid control method and achieved a synchronized reciprocating-flow of fluid and the precise control of the flow velocity of fluid in multiple channels using a single air-source pressure control device. Then, we used the CAPC chip to perform rapid, simultaneous enzyme-linked immunosorbent assay (ELISA) detection of four inflammatory markers (CRP, PCT, IL-6, SAA). The results showed that the CAPC chip can complete qualitative and quantitative detection of these four inflammatory markers within 5 min, which is the fastest ELISA detection for simultaneous detection of multiple protein biomarkers so far. Furthermore, we used the CAPC chip to detect these four inflammatory markers in simulated serum samples and provide prompt information regarding the classification and severity of infection. These findings demonstrate the potential of the CAPC chip for rapid, simultaneous, multiplex immunoassays.","PeriodicalId":85,"journal":{"name":"Lab on a Chip","volume":" 14","pages":" 3506-3515"},"PeriodicalIF":6.1,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144245374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rapid screening of CO2 capture fluids† 二氧化碳捕获液的快速筛选。

IF 6.1 2区工程技术

Lab on a Chip Pub Date : 2025-05-19 DOI: 10.1039/D4LC00772G

Yaohao Guo, Feng Li, Sepehr Saber, Mohammad Zargartalebi, Siyu Sonia Sun, Yurou Celine Xiao, Bo Bao, Zhi Xu and David Sinton

{"title":"Rapid screening of CO2 capture fluids†","authors":"Yaohao Guo, Feng Li, Sepehr Saber, Mohammad Zargartalebi, Siyu Sonia Sun, Yurou Celine Xiao, Bo Bao, Zhi Xu and David Sinton","doi":"10.1039/D4LC00772G","DOIUrl":"10.1039/D4LC00772G","url":null,"abstract":"The evaluation of CO2 capture fluids is crucial for the advancement of carbon capture technologies. Recent advancements in amine-based carbon capture fluids motivate a broad search for high-performance fluids and the development of methods capable of exploring a large chemical space. Here, we present a microfluidic approach paired with automated image processing and density functional theory simulations that enables comprehensive rapid screening of capture fluids. The principle of measurement leverages the ability to monitor phase expansion and contraction in fixed-volume dead-end channels. This approach enables fast comparative assessments of reaction kinetics and thermodynamic parameters, including CO2 absorption rate (∼30 s), desorption rate (∼30 s), absorption capacity (∼20 min), and vapor pressure (∼5 min), exceeding the speed of conventional methods by two orders of magnitude. The method is broadly applicable, effective for primary, secondary, and tertiary amine types. Rapid screening of capture fluids holds promise for the accelerated discovery of improved CO2 capture processes and an opportunity for the microfluidics community to contribute to decarbonization efforts.","PeriodicalId":85,"journal":{"name":"Lab on a Chip","volume":" 12","pages":" 2918-2925"},"PeriodicalIF":6.1,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/lc/d4lc00772g?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144087765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of the potential application of kaemperide in hyperuricemia based on a kidney-on-a-chip† 基于肾芯片的坎培利在高尿酸血症中的潜在应用研究。

IF 6.1 2区工程技术

Lab on a Chip Pub Date : 2025-05-17 DOI: 10.1039/D4LC01086H

Xinyu Song, Lili Zhao, Yingying Tian, Chen Yang, Ting Cao and Jiayu Zhang

{"title":"Investigation of the potential application of kaemperide in hyperuricemia based on a kidney-on-a-chip†","authors":"Xinyu Song, Lili Zhao, Yingying Tian, Chen Yang, Ting Cao and Jiayu Zhang","doi":"10.1039/D4LC01086H","DOIUrl":"10.1039/D4LC01086H","url":null,"abstract":"Hyperuricemia (HUA), a serious metabolic disease that manifests as an elevated serum uric acid (SUA) level, is closely related to gout, hypertension, diabetes, coronary heart disease, chronic kidney disease, and other conditions. Here, we have investigated the potential of kaemperide, a natural flavonoid, in the treatment of HUA based on a kidney-on-a-chip for the first time. The result reveals that kaemperide enhances cell viability, alleviates the UA-induced inflammatory response and promotes UA excretion significantly. Through network pharmacology analysis, URAT1, an important uric acid transporter, is identified as the potential target of kaemperide. Immunofluorescence analysis and surface plasmon resonance confirm a strong, dose-dependent binding between kaemperide and URAT1. Additionally, molecular docking elucidates the specific interaction sites and binding mechanism, and immunofluorescence analysis operated in the kidney-on-a-chip verifies the binding interaction model. In summary, this study demonstrates kaemperide as a promising HUA drug candidate for the first time, and provides a good experimental platform for the nephropathy studies and corresponding drug screening.","PeriodicalId":85,"journal":{"name":"Lab on a Chip","volume":" 13","pages":" 3254-3269"},"PeriodicalIF":6.1,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144172083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Well-defined assembly of plasmonic metal nanoparticles by dielectrophoresis for highly sensitive SERS-active substrates. 等离子体金属纳米颗粒在高敏感sers活性衬底上的良好定义组装。

IF 6.1 2区工程技术

Lab on a Chip Pub Date : 2025-05-16 DOI: 10.1039/d5lc00238a

Yun Su Yeo,Jaejun Park,Sunghoon Yoo,Dong Hwan Nam,Hayoung Kim,Tae Jae Lee,Gyu Leem,Jae-Sung Kwon,Seunghyun Lee

引用次数: 0

A SAW-driven modular acoustofluidic tweezer. saw驱动的模块化声流镊。

IF 6.1 2区工程技术

Lab on a Chip Pub Date : 2025-05-15 DOI: 10.1039/d4lc00924j

Dachuan Sang, Suyu Ding, Qinran Wei, Fengmeng Teng, Haixiang Zheng, Yu Zhang, Dong Zhang, Xiasheng Guo

{"title":"A SAW-driven modular acoustofluidic tweezer.","authors":"Dachuan Sang, Suyu Ding, Qinran Wei, Fengmeng Teng, Haixiang Zheng, Yu Zhang, Dong Zhang, Xiasheng Guo","doi":"10.1039/d4lc00924j","DOIUrl":"https://doi.org/10.1039/d4lc00924j","url":null,"abstract":"In surface acoustic wave (SAW)-driven acoustofluidic tweezers (AFTs), most setups are integrated on a piezoelectric substrate for a single purpose, limiting the reusability and versatility of devices fabricated using complex MEMS technologies. Meanwhile, prevalent devices exhibit anisotropy in SAW excitation and propagation, as well as optical birefringence and limited transmittance. This work presents a SAW-driven modular acoustofluidic tweezer consisting of up to four replaceable interdigital transducer (IDT) modules and a function module assembled on a common base. Since the IDT modules are separated, each can be fabricated using the piezoelectric substrate best suited to the requirements. For example, SAWs generated from different directions can simultaneously propagate along the X-axis of 128° Y-cut LiNbO3, enabling highly efficient excitations. The generated SAWs couple into the function module with excellent optical properties and convert into Lamb waves, which then leak into the microfluidic domain and act on the fluid/particles. All modules are connected via standardized interfaces, eliminating potential instabilities caused by wired connections. The reliability of the setup is demonstrated via particle/cell patterning, separation, and concentration experiments, during which the replaceability and reusability of different modules, and the other advantages of the setup, e.g., simple assembly, ease of operation, and application flexibility, are proven.","PeriodicalId":85,"journal":{"name":"Lab on a Chip","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Compartmentalized perfusion for temporal control of the chemical microenvironment of iPSC-derived cardiac cells† 分区灌注对ipsc源性心肌细胞化学微环境的时间控制。

IF 6.1 2区工程技术

Lab on a Chip Pub Date : 2025-05-15 DOI: 10.1039/D5LC00072F

Kaisa Tornberg, Wolfram Grötsch, Niina Ritari, Saara Haikka, Lassi Sukki, Katriina Aalto-Setälä, Mari Pekkanen-Mattila and Pasi Kallio

{"title":"Compartmentalized perfusion for temporal control of the chemical microenvironment of iPSC-derived cardiac cells†","authors":"Kaisa Tornberg, Wolfram Grötsch, Niina Ritari, Saara Haikka, Lassi Sukki, Katriina Aalto-Setälä, Mari Pekkanen-Mattila and Pasi Kallio","doi":"10.1039/D5LC00072F","DOIUrl":"10.1039/D5LC00072F","url":null,"abstract":"Organ-on-chip structures are predicted to have a significant influence in drug research. In these structures, perfusion can provide cells a more controllable environment to receive signaling molecules. In many current organ-on-chip applications, perfusion is used for shear stress stimulus for the cells, but it can also provide a more precise way of controlling the chemical microenvironment around the cells. In this paper, we propose an open-top organ-on-chip structure with compartment-specific perfusion to introduce stimulating molecules to cells with only minimal extra unspecific stimulus. Using numerical simulations, we show that shear stress sensed by the cells within the structure is low. We further validated the flow profile experimentally. We showed that the hiPSC-CMs accommodate to the flow environment where the shear stress is kept below 0.035 mPa. We also show that the beating rate of hiPSC-CMs increases due to the stimulation provided by chemical stimulant molecules introduced through the flow.","PeriodicalId":85,"journal":{"name":"Lab on a Chip","volume":" 12","pages":" 2961-2976"},"PeriodicalIF":6.1,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/lc/d5lc00072f?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143982519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0