Chemical Reviews最新文献

{"title":"Colloidal Synthesis of Plasmonic Complex Metal Nanoparticles: Sequential Execution of Multiple Chemical Toolkits Increases Morphological Complexity","authors":"Insub Jung, Sungwoo Lee, Soohyun Lee, Jeongwon Kim, Sunwoo Kwon, Hyunji Kim, Sungho Park","doi":"10.1021/acs.chemrev.4c00897","DOIUrl":"https://doi.org/10.1021/acs.chemrev.4c00897","url":null,"abstract":"In nature, complexity emerges systematically, progressing from atoms to molecules, cells, and, ultimately, complex living organisms. This natural bottom-up evolution inspired chemists to devise similarly organized processes for the creation of complex artificial matter. Similarly, the systematic design of customizable, complex nanocrystals has long been a fundamental goal. In this review, we present a comprehensive collection of chemical toolkits consisting of versatile, on-demand steps for the sequential synthesis of morphologically complex plasmonic nanoparticles (NPs). By integrating multistep synthetic routes, we introduce a list of chemical toolkits that enable combinable synthetic steps. This approach facilitates the controlled, multistep synthesis of shape-complex plasmonic NPs. We demonstrate how these designable chemical toolkits, when applied sequentially or in tailored combinations, enable the rational design of advanced plasmonic nanostructures with unprecedented complexity and structural hierarchy. This ultimately opens the door to an extensive, systematically expandable library of nanostructures with tailored functionalities. Through the advancement of this rationally designed synthetic approach, we aim to establish a “multiple stepwise synthesis” framework for fabricating shape-complex plasmonic building blocks, thus providing a roadmap for designing the next generation of plasmonic NPs.","PeriodicalId":32,"journal":{"name":"Chemical Reviews","volume":"589 1","pages":""},"PeriodicalIF":62.1,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144268962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Introduction: Soft Robotics","authors":"Ritu Raman, Xiaodong Chen, Xuanhe Zhao","doi":"10.1021/acs.chemrev.5c00356","DOIUrl":"https://doi.org/10.1021/acs.chemrev.5c00356","url":null,"abstract":"Published as part of <i>Chemical Reviews</i> special issue “Soft Robotics”. Biological systems are capable of dexterous and adaptable behaviors across length scales. Replicating these behaviors in human-made machines thus requires drawing inspiration from nature. In recent years, roboticists have identified compliance as a key design feature of biological sensors and actuators, enabling closed-loop control of complex behaviors such as locomotion, feeding, and manipulation that are central to life. Integrating compliance into the functional components of autonomous machines has inspired and accelerated the growth of “soft robotics” as a discipline. In this special issue on <i>Soft Robotics</i>, we highlight emerging frontiers in compliant sensing and actuation, novel materials and manufacturing techniques for fabricating soft bioinspired and biohybrid systems, and real-world applications of compliant machines. The featured reviews outline an exciting vision for the future of soft robotics that promises to advance the safety, reliability, and sustainability of autonomous machines. Despite rapid progress in soft materials, sensors, and actuators, achieving seamless sensorimotor integration in soft robots remains a challenge. A comprehensive review from Xiaodong Chen and colleagues explores this emerging topic by examining the foundations of sensorimotor functions. (1) The authors first outline the current state-of-the-art in soft sensing mechanisms (pressure, strain, temperature, optical, chemical, acoustic, and electromagnetic) and actuation mechanisms (fluidic, electroactive, magnetic, optical, thermal, chemical) and then highlight efforts to combine these into sensorimotor control architectures, drawing inspiration from biological systems. In particular, this review considers how artificial intelligence (AI) integrated with soft robotics can enable adaptive and responsive control in dynamic environments, enabling high-level functional behaviors such as decision making and autonomous learning. Adaptive and responsive control requires improvements in stretchable electronics, motivating a review by Michael Dickey and colleagues on methods to manufacture flexible conductors via sintering of liquid metal particles. (2) The review surveys the benefits and limitations of ten sintering methods (mechanical, thermal, laser, sonication, electrochemical, Ag flake bridges, chemical, evaporation-induced, field-based alignment, and freezing-activated) for forming soft, stretchable, and conductive materials for functional use in soft robotics. The authors also highlight key technical challenges, including the development of practical manufacturing and processing methods, that need to be addressed to enable scalable fabrication of high-performance soft electronics for real-world applications. Real-world applications of soft robots are broad and include exploratory machines, augmented reality systems, and healthcare. Given the particularly significant and growing ","PeriodicalId":32,"journal":{"name":"Chemical Reviews","volume":"29 2 1","pages":""},"PeriodicalIF":62.1,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144260689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Introduction: Soft Robotics","authors":"Ritu Raman*, Xiaodong Chen and Xuanhe Zhao, ","doi":"10.1021/acs.chemrev.5c0035610.1021/acs.chemrev.5c00356","DOIUrl":"https://doi.org/10.1021/acs.chemrev.5c00356https://doi.org/10.1021/acs.chemrev.5c00356","url":null,"abstract":"","PeriodicalId":32,"journal":{"name":"Chemical Reviews","volume":"125 11","pages":"5055–5056 5055–5056"},"PeriodicalIF":51.4,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144253016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to Role of Bis(phosphinimino)methanides as Universal Ligands in the Coordination Sphere of Metals across the Periodic Table","authors":"Archana Jain, Himadri Karmakar, Peter W. Roesky, Tarun K. Panda","doi":"10.1021/acs.chemrev.5c00313","DOIUrl":"https://doi.org/10.1021/acs.chemrev.5c00313","url":null,"abstract":"<b>Page 13326, Section 2. Synthesis of Bis(phosphinimino)methanide Ligands─the last paragraph in this section should be revised as follows:</b> Symmetrically <i>p</i>-tolyl substituted bis(phosphinimino)methane [CH<sub>2</sub>(Ph<sub>2</sub>PN<i>p</i>Tol)<sub>2</sub>] (<b>1Tol</b>) was also prepared by using the most common strategy as shown in Scheme 1a from the reaction of bis(diphenylphosphino)methane (dppm) with 2 equiv of the <i>p</i>-tolylazide (Scheme 1a). (1) New unsymmetrically substituted bis(phosphinimino)methanes [(Ph<sub>2</sub>PNC<sub>6</sub>H<sub>4</sub>Me)CH<sub>2</sub>(Ph<sub>2</sub>PNC<sub>6</sub>H<sub>4</sub>ImR)] (Im = imidazole; R = Me, Bn, <sup><i>i</i></sup>Pr) with imidazole functions were also prepared from the reaction of bis(diphenylphosphino)methane (dppm) with 1 equiv of the corresponding azide and then subsequent addition of 1 equiv of <i>p</i>-tolylazide in CH<sub>2</sub>Cl<sub>2</sub> as shown in Scheme 2a. (2) <b>Page 13327, Section 3.1. Alkali Metal Complexes─the fifth paragraph in this section should be revised as follows</b> Bis(iminophosphoryl) substituted lithium chloride carbenoids, [Cl{C(Ph<sub>2</sub>PNR)<sub>2</sub>}Li]<sub>2</sub> (R = Ad (<b>iv</b>) and <i>p</i>-Tol (<b>v</b>)) were prepared either by metal/halide exchange reaction of dilithiomethandiides [{C(Ph<sub>2</sub>PNR)<sub>2</sub>}Li<sub>2</sub>]<sub>2</sub> (R = Ad (<b>i</b>) and <i>p</i>-Tol (<b>ii</b>)) or by direct metalation of a protonated precursor [Cl{CH(Ph<sub>2</sub>PNAd)<sub>2</sub>}]<sub>2</sub> (<b>iii</b>) (Scheme 3a). The precursor compounds [{C(Ph<sub>2</sub>PNR)<sub>2</sub>}Li<sub>2</sub>]<sub>2</sub> (R = Ad (<b>i</b>) and <i>p</i>-Tol (<b>ii</b>)) were obtained from the double deprotonation of <b>1Ad</b>/<b>1Tol</b> with 2 equiv of <sup><i>n</i></sup>BuLi/MeLi, whereas compound [Cl{CH(Ph<sub>2</sub>PNAd)<sub>2</sub>}]<sub>2</sub> (<b>iii</b>) was prepared by the treatment of <b>1Ad</b> with 1 equiv of MeLi followed by 1 equiv of C<sub>2</sub>Cl<sub>6</sub>, respectively, in an appropriate solvent (Scheme 3a). (1,3) The methandiides <b>iv</b> and <b>v</b> assumed dimeric and symmetric structures in the solid that were solvated differently depending on the size of substituents present on nitrogen atoms (Scheme 3a). (3) <b>Page 13327, Section 3.1. Alkali Metal Complexes─the fifth paragraph in this section should be revised as follows</b> Stasch’s research group also reported the synthesis and structural characterization of a series of dilithium methandiide complexes having the chemical compositions [{C(Ph<sub>2</sub>PNDipp)<sub>2</sub>}Li<sub>2</sub>]<sub>2</sub> (<b>vi</b>), [{C(Ph<sub>2</sub>PNDipp)<sub>2</sub>}Li<sub>2</sub>(OEt<sub>2</sub>)<sub>2</sub>] (<b>vii</b>), [{C(Ph<sub>2</sub>PNDipp)<sub>2</sub>}Li<sub>2</sub>(THF)<sub>3</sub>] (<b>viii</b>), [{C(Ph<sub>2</sub>PNDipp)<sub>2</sub>}Li<sub>2</sub>(THF)<sub>2</sub>] (<b>ix</b>), and [{C(Ph<sub>2</sub>PNDipp)<sub>2</sub>}Li<sub>2</sub>(PMDTA)] (<b>x</b>), (PMDTA = <i>N,N","PeriodicalId":32,"journal":{"name":"Chemical Reviews","volume":"23 6 1","pages":""},"PeriodicalIF":62.1,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144260690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Studying Noncovalent Interactions in Molecular Systems with Machine Learning","authors":"Serhii Tretiakov, AkshatKumar Nigam, Robert Pollice","doi":"10.1021/acs.chemrev.4c00893","DOIUrl":"https://doi.org/10.1021/acs.chemrev.4c00893","url":null,"abstract":"Noncovalent interactions (NCIs) is an umbrella term for a multitude of typically weak interactions within and between molecules. Despite the low individual energy contributions, their collective effect significantly influences molecular behavior. Accordingly, understanding these interactions is crucial across fields like catalysis, drug design, materials science, and environmental chemistry. However, predicting NCIs is challenging, requiring at least molecular mechanics-level pairwise energy contributions or efficient quantum mechanical electron correlation treatment. In this review, we investigate the application of machine learning (ML) to study NCIs in molecular systems, an emerging research field. ML excels at modeling complex nonlinear relationships, and is capable of integrating vast data sets from experimental and theoretical sources. It offers a powerful approach for analyzing interactions across scales, from small molecules to large biomolecular assemblies. Specifically, we examine data sets characterizing NCIs, compare molecular featurization techniques, assess ML models predicting NCIs explicitly, and explore inverse design approaches. ML enhances predictive accuracy, reduces computational costs, and reveals overlooked interaction patterns. By identifying current challenges and future opportunities, we highlight how ML-driven insights could revolutionize this field. Overall, we believe that recent proof-of-concept studies foreshadow exciting developments for the study of NCIs in the years to come.","PeriodicalId":32,"journal":{"name":"Chemical Reviews","volume":"3 1","pages":""},"PeriodicalIF":62.1,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144252854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioinspired Multifunctional and Dynamic Color-Tuning Photonic Devices","authors":"Abbas Ahmed, Shuai Zhou, Binhong Yu, Tiantian Li, Josh N. Bodin, Songshan Zeng, Xuesong Jiang, Luyi Sun","doi":"10.1021/acs.chemrev.4c00844","DOIUrl":"https://doi.org/10.1021/acs.chemrev.4c00844","url":null,"abstract":"Tremendous progress has been achieved in comprehending the scientific principles governing nature and translating them into practical applications. Among the areas of interest within photonic systems, bioinspired color-tuning devices originating from physical structure modulation hold significant importance. This Review provides an overview of cutting-edge advancements in bioinspired structural color-tuning photonic devices across various applications. First, we delve into the origins, design principles, and fundamental physics underlying bioinspired structural color systems by showcasing diverse living species found in nature. Subsequently, we explore various photonic nano/microscale building blocks, including one-dimensional (1D), two-dimensional (2D), and three-dimensional (3D) structures, along with their fabrication techniques. Additionally, we present various biomimetic material systems and strategies for fabricating dynamic structural color devices. Furthermore, we discuss recent breakthroughs in biomimetic photonic systems across key application areas including sensing, interactive soft robotics, digital information encryption/decryption, dynamic displays, and energy. In summary, this Review provides a comprehensive analysis of bioinspired color-tuning photonic devices, shedding light on their intricate structure–function relationships, and aims to inspire the adoption and development of advanced color-tuning strategies. Finally, we address current challenges and offer insights into potential groundbreaking developments in the field of bioinspired optical materials.","PeriodicalId":32,"journal":{"name":"Chemical Reviews","volume":"21 1","pages":""},"PeriodicalIF":62.1,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144252856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent Advances in the Use of Ionic Liquids and Deep Eutectic Solvents for Lignocellulosic Biorefineries and Biobased Chemical and Material Production","authors":"Pedro Verdía Barbará, Hemant Choudhary, Pedro S. Nakasu, Amir Al-Ghatta, Yinglei Han, Cynthia Hopson, Raul I. Aravena, Dhirendra Kumar Mishra, Antonio Ovejero-Pérez, Blake A. Simmons, Jason P. Hallett","doi":"10.1021/acs.chemrev.4c00754","DOIUrl":"https://doi.org/10.1021/acs.chemrev.4c00754","url":null,"abstract":"Biorefineries, which process biomass feedstocks into valuable (bio)products, aim to replace fossil fuel-based refineries to produce energy and chemicals, reducing environmental and health hazards, including climate change, and supporting a sustainable economy. In particular, lignocellulose-based biorefineries, utilizing the most abundant renewable feedstock on Earth, have significant potential to supply sustainable energy, chemicals and materials. Ionic liquids (ILs, organic salts with low melting temperatures) and deep eutectic solvents (DESs, mixtures with eutectic points lower than the ideal mixture) are capable of dissolving some of the key lignocellulose polymers, and even the whole biomass. Furthermore, they have intrinsic advantages over molecular solvents, including safer usage profiles and high tunability, which allow tailored physicochemical properties. Such properties provide unique opportunities for the development of new processes that could unlock the full potential of future biorefineries. Here, we review the current state of lignocellulosic biomass processing with ILs and DESs, with a specific focus on the pretreatment chemistry, process flow and products from each component; followed by discussions on sustainability assessments and technological challenges. We aim to inform the research community about the opportunities, challenges and perspectives in developing truly sustainable lignocellulose-based biorefineries.","PeriodicalId":32,"journal":{"name":"Chemical Reviews","volume":"10 1","pages":""},"PeriodicalIF":62.1,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144229163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantum Machine Learning in Drug Discovery: Applications in Academia and Pharmaceutical Industries","authors":"Anthony M. Smaldone, Yu Shee, Gregory W. Kyro, Chuzhi Xu, Nam P. Vu, Rishab Dutta, Marwa H. Farag, Alexey Galda, Sandeep Kumar, Elica Kyoseva, Victor S. Batista","doi":"10.1021/acs.chemrev.4c00678","DOIUrl":"https://doi.org/10.1021/acs.chemrev.4c00678","url":null,"abstract":"The nexus of quantum computing and machine learning─quantum machine learning─offers the potential for significant advancements in chemistry. This Review specifically explores the potential of quantum neural networks on gate-based quantum computers within the context of drug discovery. We discuss the theoretical foundations of quantum machine learning, including data encoding, variational quantum circuits, and hybrid quantum-classical approaches. Applications to drug discovery are highlighted, including molecular property prediction and molecular generation. We provide a balanced perspective, emphasizing both the potential benefits and the challenges that must be addressed.","PeriodicalId":32,"journal":{"name":"Chemical Reviews","volume":"16 1","pages":""},"PeriodicalIF":62.1,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144229323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metal–N-Heterocyclic Carbene Complexes in Buchwald–Hartwig Amination Reactions","authors":"Sourav Sekhar Bera, Greta Utecht-Jarzyńska, Shiyi Yang, Steven P. Nolan, Michal Szostak","doi":"10.1021/acs.chemrev.5c00088","DOIUrl":"https://doi.org/10.1021/acs.chemrev.5c00088","url":null,"abstract":"We present a comprehensive overview of the Buchwald–Hartwig amination, one of the most useful methods for C–N bond formation, mediated by NHC–transition-metal-complexes, covering the literature since 1999 (the first report on Buchwald–Hartwig amination by Nolan et al.) through December 2024. Palladium– and nickel–N-heterocyclic carbene (NHC) complexes are key contributors to Buchwald–Hartwig amination and are thoroughly discussed in this review, along with examples of cobalt and rhodium–NHC complexes. Apart from the conventional aryl/alkyl amines and aryl halides coupling, participation of versatile and challenging functional groups like pseudohalides, amides, ester, sulfoxides, unactivated aryl sulfamates, carbamates, pivalates, as well as novel electrophiles, such as aryl fluorides, methyl ethers, and silyloxyarenes, are also presented. The Reader is provided with an overview of the key role of metal–NHC complexes, their crucial role in constructing carbon–nitrogen bonds, and their importance in medicinal and materials chemistries as well as in drug discovery.","PeriodicalId":32,"journal":{"name":"Chemical Reviews","volume":"17 1","pages":""},"PeriodicalIF":62.1,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144237588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Noncovalent Aggregation for Diverse Properties in Hydrogels: A Comprehensive Review","authors":"Sidi Duan, Mutian Hua, Chuan Wei Zhang, Wen Hong, Yichen Yan, Abdullatif Jazzar, Chi Chen, Pengju Shi, Muqing Si, Dong Wu, Zishang Lin, Ping He, Yingjie Du, Ximin He","doi":"10.1021/acs.chemrev.5c00069","DOIUrl":"https://doi.org/10.1021/acs.chemrev.5c00069","url":null,"abstract":"The rapid expansion of hydrogel research over recent decades has bridged fundamental chemistry and physics with advanced materials science applications. This field necessitates comprehensive and in-depth review and discussion of the diverse and rapidly expanding body of research, thereby providing a cohesive understanding that can drive future innovations and applications. This review delves into the role of noncovalent interactions in hydrogel aggregation, a critical mechanism for creating desired microstructures that enhance material properties. Inspired by natural molecular architecture, this paper explores how synthetic hydrogels exploit hydrogen bonds, hydrophobic interactions, and other noncovalent forces to create robust, multifunctional, and water-rich networks. We further discuss methods to induce these interactions and the unique properties resulting from the formed structures. With these methods, we provide insights into the art of manipulating aggregated structures within hydrogels to develop adaptable, tunable materials for a broad range of applications, including bioengineering, robotics and soft electronics, highlighting their significant practical value across interdisciplinary fields.","PeriodicalId":32,"journal":{"name":"Chemical Reviews","volume":"249 1","pages":""},"PeriodicalIF":62.1,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144229326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}