IF 3.8 2区化学

Analytical and Bioanalytical Chemistry Pub Date : 2025-03-01 Epub Date: 2024-12-17 DOI: 10.1007/s00216-024-05683-1

Yuxin Wei, Qingqing Bai, Xinlu Ning, Xiaofan Bai, Jie Lv, Meng Li

{"title":"Covalent organic framework derived single-atom copper nanozymes for the detection of amyloid-β peptide and study of amyloidogenesis.","authors":"Yuxin Wei, Qingqing Bai, Xinlu Ning, Xiaofan Bai, Jie Lv, Meng Li","doi":"10.1007/s00216-024-05683-1","DOIUrl":"10.1007/s00216-024-05683-1","url":null,"abstract":"Sensitive and accurate detection of the amyloid-β (Aβ) monomer is of fundamental significance for early diagnosis of Alzheimer's disease (AD). Herein, inspired by the specific Cu-Aβ monomer coordination, a cutting-edge colorimetric assay based on single-atom Cu anchored N-doped carbon nanospheres (Cu-NCNSs) was developed for Aβ monomer detection and an amyloidogenesis study. By directly pyrolyzing Cu2+-incorporated covalent organic frameworks (COFs), the resulting Cu-NCNSs with a high loading of Cu (8.04 wt %) exhibited outstanding peroxidase-like activity. The strong binding affinity of Aβ monomer to Cu-NCNSs effectively inhibited their catalytic activity, providing the basis for the colorimetric assay. The Cu-NCNSs-based sensor showed a detection limit of 1.182 nM for Aβ monomer, surpassing traditional techniques in terms of efficiency, accuracy and simplicity. Moreover, the system was successfully utilized for Aβ monomer detection in rat cerebrospinal fluid (CSF). Notably, the distinct inhibitory effects of monomeric and aggregated Aβ species on the catalytic activity of Cu-NCNSs were allowed for monitoring of the dynamic aggregation process of Aβ. Compared to thioflavin T (ThT), the most widely used amyloid dye, the detection system exhibited greater sensitivity towards toxic Aβ oligomers, which was crucial for early AD diagnosis and treatment. Our work not only sheds light on the rational design of highly active single-atom nanozymes from COFs but also expands the potential applications of nanozymes in early disease diagnosis.","PeriodicalId":462,"journal":{"name":"Analytical and Bioanalytical Chemistry","volume":" ","pages":"1081-1092"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142833591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

AuNPs/GO/Pt microneedle electrochemical sensor for in situ monitoring of hydrogen peroxide in tomato stems in response to wounding stimulation.

IF 3.8 2区化学

Analytical and Bioanalytical Chemistry Pub Date : 2025-03-01 Epub Date: 2025-01-24 DOI: 10.1007/s00216-024-05728-5

Xiaolong Yang, Doudou Huo, Yiran Tian, Xingliu Geng, Liang Xu, Daji Zhong, Rong Zhou, Songzhi Xu, Yali Zhang, Lijun Sun

{"title":"AuNPs/GO/Pt microneedle electrochemical sensor for in situ monitoring of hydrogen peroxide in tomato stems in response to wounding stimulation.","authors":"Xiaolong Yang, Doudou Huo, Yiran Tian, Xingliu Geng, Liang Xu, Daji Zhong, Rong Zhou, Songzhi Xu, Yali Zhang, Lijun Sun","doi":"10.1007/s00216-024-05728-5","DOIUrl":"10.1007/s00216-024-05728-5","url":null,"abstract":"Hydrogen peroxide (H2O2) is a critical signaling molecule with significant roles in various physiological processes in plants. Understanding its regulation through in situ monitoring could offer deeper insights into plant responses and stress mechanisms. In this study, we developed a microneedle electrochemical sensor to monitor H2O2 in situ, offering deeper insights into plant stress responses. The sensor features a platinum wire (100 µm diameter) modified with graphene oxide (GO) and gold nanoparticles (AuNPs) as the working electrode, an Ag/AgCl wire (100 µm diameter) as the reference electrode, and an untreated platinum wire (100 µm diameter) as the counter electrode. This innovative design enhances sensitivity and selectivity through the high catalytic activity of AuNPs, increased surface area from GO, and the superior conductivity of platinum. Operating at a low potential of -0.2 V to minimize interference, the sensor detects H2O2 concentrations from 10 to 1000 µM with high accuracy. In situ monitoring of H2O2 dynamics in tomato stems under the wounding stimulation reveals that H2O2 concentration increases as the sensor approaches the wound site, indicating localized production and transport of H2O2. This approach not only improves H2O2 monitoring in plant systems but also paves the way for exploring its generation, transport, and elimination mechanisms.","PeriodicalId":462,"journal":{"name":"Analytical and Bioanalytical Chemistry","volume":" ","pages":"1067-1079"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Large fluctuations in NSPT computations: a lesson from O(N) non-linear sigma models

IF 4.2 2区物理与天体物理

The European Physical Journal C Pub Date : 2025-03-01 DOI: 10.1140/epjc/s10052-025-13887-7

Paolo Baglioni, Francesco Di Renzo

{"title":"Large fluctuations in NSPT computations: a lesson from O(N) non-linear sigma models","authors":"Paolo Baglioni, Francesco Di Renzo","doi":"10.1140/epjc/s10052-025-13887-7","DOIUrl":"10.1140/epjc/s10052-025-13887-7","url":null,"abstract":"<div>In the last three decades, numerical stochastic perturbation theory (NSPT) has proven to be an excellent tool for calculating perturbative expansions in theories such as Lattice QCD, for which standard, diagrammatic perturbation theory is known to be cumbersome. Despite the significant success of this stochastic method and the improvements made in recent years, NSPT apparently cannot be successfully implemented in low-dimensional models due to the emergence of huge statistical fluctuations: as the perturbative order gets higher, the signal to noise ratio is simply not good enough. This does not come as a surprise, but on very general grounds, one would expect that the larger the number of degrees of freedom, the less severe the fluctuations will be. By simulating 2D O(N) non-linear sigma models for different values of N, we show that indeed the fluctuations are tamed in the large N limit, meeting our expectations: for a large number of internal degrees of freedom (i.e. for large enough N), NSPT perturbative computation can be pushed to large perturbative orders n. By re-expressing our perturbative expansions as power series in the gN (’t Hooft) coupling, we show some evidence that at any given order n there is a tendency to gaussianity for the stochastic process distributions at large N. By summing our series, we can verify leading order results for the energy and its (field theoretic) variance in the large N limit. We finally establish general relationships between the various perturbative orders in the expansion of the (field theoretic) variance of a given observable and combinations of variances and covariances of given orders NSPT stochastic processes. Having established all this, we conclude discussing interesting applications of NSPT computations in the context of theories similar to O(N) (i.e. (CP(N-1)) models).</div>","PeriodicalId":788,"journal":{"name":"The European Physical Journal C","volume":"85 2","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1140/epjc/s10052-025-13887-7.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143527662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterization and in vitro cellular activity assessment of photodynamic composite nanocarriers for gliomas treatment

IF 2.1 4区材料科学

Journal of Nanoparticle Research Pub Date : 2025-03-01 DOI: 10.1007/s11051-025-06268-4

Yongxu Yang, Wenxiu Li, Junhong Zhou, Yang Yu, Shujie Liu, Qing Xu

引用次数: 0

Towards Next-Generation Membrane Bioreactors: Innovations, Challenges, and Future Directions

IF 6.4 2区环境科学与生态学

Current Pollution Reports Pub Date : 2025-03-01 DOI: 10.1007/s40726-025-00345-x

K. Khoiruddin, R. Boopathy, S. Kawi, I. G. Wenten

{"title":"Towards Next-Generation Membrane Bioreactors: Innovations, Challenges, and Future Directions","authors":"K. Khoiruddin, R. Boopathy, S. Kawi, I. G. Wenten","doi":"10.1007/s40726-025-00345-x","DOIUrl":"10.1007/s40726-025-00345-x","url":null,"abstract":"<div><h3>Purpose of Review</h3>This review provides a comprehensive analysis of the current state and future prospects of membrane bioreactors (MBRs), focusing on recent advancements in membrane materials, innovative design concepts, and strategies to optimize biodegradation processes. Additionally, it highlights the transformative role of artificial intelligence (AI), machine learning (ML), and hybrid configurations in advancing MBR.<h3>Recent Findings</h3> Hybrid MBR systems that incorporate advanced oxidation processes (AOPs) and other processes demonstrate enhanced micropollutant removal and treatment efficiency. MBR with nanocomposite and bio-inspired membranes exhibit improved fouling resistance, water flux, and mechanical strength. Significant innovations also include the application of AI-driven models, such as random forests and neural networks, to predict fouling behavior and optimize operational parameters in MBRs.<h3>Summary</h3>Recent progress in MBR technology, especially through new membrane materials and hybrid systems, plays an important role in improving MBR performance for contaminant removal and reducing fouling in wastewater treatment. Additionally, incorporating AI and optimizing operational parameters can further improve the efficiency, effectiveness, and reliability of these systems. </div>","PeriodicalId":528,"journal":{"name":"Current Pollution Reports","volume":"11 1","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143527638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of Crystalline Phases of Electroactive Forms of a Composite of Polyvinylidene Fluoride and Tetrafluoroethylene Copolymer with Nanographite

IF 0.5

Journal of Surface Investigation: X-ray, Synchrotron and Neutron Techniques Pub Date : 2025-03-01 DOI: 10.1134/S1027451024701234

V. I. Bachurin, N. G. Savinski, A. P. Khramov, M. A. Smirnova, R. V. Selyukov

{"title":"Analysis of Crystalline Phases of Electroactive Forms of a Composite of Polyvinylidene Fluoride and Tetrafluoroethylene Copolymer with Nanographite","authors":"V. I. Bachurin, N. G. Savinski, A. P. Khramov, M. A. Smirnova, R. V. Selyukov","doi":"10.1134/S1027451024701234","DOIUrl":"10.1134/S1027451024701234","url":null,"abstract":"The work examines the effect of crystallization conditions of vinylidene fluoride (VDF) and tetrafluoroethylene (TFE) copolymer (F-42) from aprotic solvents (dimethyl sulfoxide (DMSO) and dimethylformamide (DMF)) under isothermal conditions at temperatures of 60, 90, and 150°C on the phase composition of the films. The content of crystalline phases in F-42 films is analyzed using Fourier-transform infrared spectroscopy, Raman spectroscopy, and X-ray phase analysis. The effect of nanographite fillers on the crystalline phases of the copolymer films is also studied. Nanographite fillers alter the crystalline structure of the polymer piezoelectric films and their piezoelectric properties, forming electroactive β and γ phases with high content during crystallization from 5-wt-% solutions of aprotic solvents. Some analytical features of the crystalline allotrope phase content are identified using these methods. The total content of crystalline electroactive phases in the VDF/TFE copolymer during isothermal crystallization from DMSO and DMF is 96–98%, while the β-phase content is 75–80%.","PeriodicalId":671,"journal":{"name":"Journal of Surface Investigation: X-ray, Synchrotron and Neutron Techniques","volume":"18 6","pages":"1340 - 1348"},"PeriodicalIF":0.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143527666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

On Si/NiSi2/Si(111) Heterostructures Obtained by Solid-Phase Deposition

IF 0.5

Journal of Surface Investigation: X-ray, Synchrotron and Neutron Techniques Pub Date : 2025-03-01 DOI: 10.1134/S1027451024701337

N. M. Mustafoeva, A. K. Tashatov, B. E. Umirzakov, M. B. Mamatova

引用次数: 0

Time-of-Flight Neutron Reflectometer for the DARIA Compact Neutron Source: Monte Carlo Simulation

IF 0.5

Journal of Surface Investigation: X-ray, Synchrotron and Neutron Techniques Pub Date : 2025-03-01 DOI: 10.1134/S102745102470160X

N. A. Grigoryeva, N. A. Kovalenko, S. V. Grigoriev

引用次数: 0

Dependence of Magnetic and Magnetoimpedance Properties of Samples of Amorphous Fe-Based Alloys on Their Shape. Influence of Glass Shell Thickness in the Case of Microwires

IF 0.5

Journal of Surface Investigation: X-ray, Synchrotron and Neutron Techniques Pub Date : 2025-03-01 DOI: 10.1134/S1027451024701520

N. S. Perov, V. V. Rodionova, S. V. Samchenko, V. V. Molokanov

{"title":"Dependence of Magnetic and Magnetoimpedance Properties of Samples of Amorphous Fe-Based Alloys on Their Shape. Influence of Glass Shell Thickness in the Case of Microwires","authors":"N. S. Perov, V. V. Rodionova, S. V. Samchenko, V. V. Molokanov","doi":"10.1134/S1027451024701520","DOIUrl":"10.1134/S1027451024701520","url":null,"abstract":"Amorphous magnetic metal alloys are a rather new class of materials compared to crystalline ones. They differ significantly from crystalline materials in their structure and physical and magnetic properties. The amorphous state of matter is a state in which there is no long-range order in the arrangement of atoms. The lack of long-range order often leads to changes in physical properties that are difficult or impossible to obtain in a solid with a crystalline structure. One important factor is the extremely small value of magnetocrystalline anisotropy, which leads to an increase in the contributions of magnetoelastic anisotropy and shape anisotropy. In the presented work, a comparative analysis of the magnetic properties of three types of samples prepared from amorphous Fe77.5Si12.5B10 alloy (ribbons, thick wires, and glass-shell microwires) has been carried out. It is found that the impedance characteristics of all the samples are quite small, although they depend on the type of the sample. For composite samples (glass-covered microwire), the magnetic properties strongly depend on both the thickness of the metallic core and the ratio of the total thickness of the microwire to the thickness of the metallic core. The obtained experimental results are presented in the form of graphical dependences.","PeriodicalId":671,"journal":{"name":"Journal of Surface Investigation: X-ray, Synchrotron and Neutron Techniques","volume":"18 6","pages":"1545 - 1550"},"PeriodicalIF":0.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143527671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of kinetic freeze-out properties in different relativistic heavy-ion collision systems at (sqrt{s_{NN}}=200) GeV

IF 2.8 3区物理与天体物理

The European Physical Journal Plus Pub Date : 2025-03-01 DOI: 10.1140/epjp/s13360-025-06119-0

Muhammad Waqas, Muhammad Ajaz, Jihane Ben Slimane, Murad Badshah, Haifa I. Alrebdi, Abd Al Karim Haj Ismail

{"title":"Evaluation of kinetic freeze-out properties in different relativistic heavy-ion collision systems at (sqrt{s_{NN}}=200) GeV","authors":"Muhammad Waqas, Muhammad Ajaz, Jihane Ben Slimane, Murad Badshah, Haifa I. Alrebdi, Abd Al Karim Haj Ismail","doi":"10.1140/epjp/s13360-025-06119-0","DOIUrl":"10.1140/epjp/s13360-025-06119-0","url":null,"abstract":"<div>We present our analysis of the identified hadrons ((pi ^+), (K^+), and p) kinetic freeze-out properties in relativistic collisions at (sqrt{s_{NN}} = 200) GeV. We analyze the transverse momentum spectra of these hadrons across various collision systems, such as copper–copper ((Cu-Cu)), zirconium–zirconium ((Zr-Zr)), ruthenium–ruthenium ((Ru-Ru)), uranium–uranium ((U-U)), and gold–gold ((Au-Au)) collisions, in distinct centrality intervals at the same center-of-mass energy using the modified Hagedorn model with embedded flow. The freeze-out parameters, namely the kinetic freeze-out temperature ((T_0)), transverse flow velocity ((beta _T)), and the entropy-related parameter (n), are extracted. Taking (T_0) and (beta _T) as common, it is observed that in all the above collisions, (T_0), (beta _T), and the parameter n diminish toward the periphery and are greater in central collisions. However, (T_0) in central collisions across all the systems remains unchanged, indicating a phase transition from hadronic matter to quark–gluon plasma. Furthermore, the temperature required for the phase transition across various systems is different. Large systems exhibit a shift in the potential start of the phase transition in peripheral collisions, which is intriguing. We also observe a direct relation between the extracted parameters and the system’s size.</div>","PeriodicalId":792,"journal":{"name":"The European Physical Journal Plus","volume":"140 2","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143527629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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