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{"title":"Control of Mask Erosion and Correction of Structure Profile in an Adapted Process of Deep Reactive Ion Etching of Silicon","authors":"O. V. Morozov","doi":"10.1134/S102745102470126X","DOIUrl":"10.1134/S102745102470126X","url":null,"abstract":"<p>The paper presents a new approach to optimizing the cyclic procedure of deep reactive ion etching (DRIE) of silicon. The etching parameters were adjusted based on direct measurements of the rates of deposition and etching processes in a cycle on the surface of oxidized silicon using a laser interferometer. A high-quality etching profile with minimal erosion of the SiO₂ mask (maximum process selectivity) was achieved by adapting the three-stage DRIE process according to the measured duration of polymer removal at the bottom of the grooves in silicon. It has been shown that the profile shape can be corrected by changing the DRIE parameters during the etching process. As a result of optimization, a recipe was obtained for etching grooves 30 µm wide to a depth of 350 µm with a wall angle of 0.36° at a process rate and selectivity of 3.4 µm/min and ~400, respectively. The adapted recipe was successfully applied in the manufacturing technology of the sensitive element of a micromechanical gyroscope.</p>","PeriodicalId":671,"journal":{"name":"Journal of Surface Investigation: X-ray, Synchrotron and Neutron Techniques","volume":"18 6","pages":"1364 - 1373"},"PeriodicalIF":0.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143527696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of Ion Treatment of Cr-Coated Zirconium Alloy (E110) on Resistance to High-Temperature Oxidation","authors":"D. V. Sidelev,&nbsp;K. A. Zinkovskii,&nbsp;D. A. Ashikhmin","doi":"10.1134/S1027451024701398","DOIUrl":"10.1134/S1027451024701398","url":null,"abstract":"<p>Two series of Cr coatings were deposited on E110 zirconium alloy by magnetron sputtering using different modes of ion surface treatment. The crystal structure and microstructure of the Cr coating and its adhesion and corrosion resistance during high-temperature oxidation in air at a temperature of 1100°C with isothermal exposure for 20 and 60 min were studied. The short-term Ar⁺ irradiation of the Zr alloy with a current density of less than 1.6 mA/cm² caused a preferential growth of Cr crystallites in (200) plane, an increase in the size of columns in the “coating-alloy” zone, and a high uniformity of the columnar microstructure over the thickness. Without ion treatment, the Cr coating was less resistant to cracking and more vulnerable to high-temperature oxidation. Due to the high permeability of the Cr coating to oxygen and nitrogen, the oxidation of Zr alloy occurred with the formation of (ZrO₂ + ZrN) layer underneath the coating. The Cr coating with (200) texture was more resistant to cracking during scratch testing. Because of a lower permeability of oxygen and nitrogen through the Cr (200) coating, the extended dendritic structures α-Zr(O,N) were formed in the Zr alloy up to a depth of 250–270 μm during prolonged air oxidation.</p>","PeriodicalId":671,"journal":{"name":"Journal of Surface Investigation: X-ray, Synchrotron and Neutron Techniques","volume":"18 6","pages":"1451 - 1459"},"PeriodicalIF":0.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143527648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pumice Adsorption of Radionuclides from Liquids: Optimization and Modeling","authors":"M. A. Gatea","doi":"10.1007/s11270-025-07833-2","DOIUrl":"10.1007/s11270-025-07833-2","url":null,"abstract":"<div><p>Nuclear operations generate significant amounts of radioactive liquids (RLs), posing a severe threat to the environment. Effective decontamination of RLs remains a challenge. This study introduces pumice as a novel, sustainable, and economical adsorbent for radionuclides removal. The characteristics of pure pumice were verified through X-ray diffraction, a scanning electron microscopy (SEM), a Fourier-transform infrared spectroscopy (FTIR), and X-ray fluorescence spectrometry. Batch experiments were conducted to evaluate the effectiveness of pumice in removing radionuclides from RLs. The gross alpha, beta, and gamma technique was used to concurrently radiologically characterize the RLs before and after decontamination. The operating conditions for the process included a 5-min stirring time, stirring speed at 100 rpm, mass of pumice 3 g/L, and a pH of 5. Initial gross beta and gamma activities were 29,766 and 4623 Bq/L, respectively, while the experiments were conducted at room temperature. The batch experiments demonstrated that pumice effectively removed 65.77% of gross beta and 61.73% of gross gamma radioactivity. The Freundlich isotherm model and the pseudo-second-order kinetic model accurately represented the adsorption process, suggesting a heterogeneity of surfaces and a chemical reaction between radionuclides and active pumice sites. System energy was endothermic and resulted in a decrease in energy dissipation and an increase in system order.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":808,"journal":{"name":"Water, Air, & Soil Pollution","volume":"236 3","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143527642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysing Soret, Dufour, and activation energy effects on heat and mass transfer thin film flow of an MHD Williamson ternary hybrid nanofluid over a non-Darcy porous stretching surface","authors":"Vishalkumar J. Prajapati,&nbsp;Ramakanta Meher","doi":"10.1140/epjp/s13360-025-06103-8","DOIUrl":"10.1140/epjp/s13360-025-06103-8","url":null,"abstract":"<div><p>This study investigates the heat and mass transfer characteristics in the thin film flow of a radiative MHD Williamson ternary hybrid nanofluid (THNF) over an unsteady permeable stretching surface. This study examines the combined effects of Soret and Dufour diffusion, activation energy, and non-uniform heat absorption or generation on fluid dynamics within a non-Darcy porous medium at the surface. The THNF consists of <i>Cu</i>, <span>(Al_2O_3)</span>, and <span>(TiO_2)</span> nanoparticles suspended in an ethylene glycol–water base fluid, chosen for its superior thermal conductivity, and enhanced heat transfer characteristics. The problem’s governing equations (PDEs) are transformed into a system of nonlinear ODEs using similarity transformations and solved using the homotopy analysis method (HAM). The impacts of essential physical parameters on fluid velocity and temperature, nanoparticle concentration, skin friction coefficient, and heat and mass transfer rates are illustrated graphically and numerically. The heat transfer rate decreases with higher Dufour number values and increases with lower Soret number values. Conversely, the opposite behaviour is observed for mass transfer. Furthermore, a comparison investigation indicates that the THNF demonstrates markedly superior heat and mass transfer rates compared to binary hybrid and mono nanofluids.</p></div>","PeriodicalId":792,"journal":{"name":"The European Physical Journal Plus","volume":"140 2","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143521599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Environmental Variability and its Impact on Phytoplankton Communities in Taiwan's Aogu Wetland","authors":"Hong-Thih Lai,&nbsp;Yi-Ming Kuo","doi":"10.1007/s11270-025-07831-4","DOIUrl":"10.1007/s11270-025-07831-4","url":null,"abstract":"<div><p>The Aogu Wetland Forest Park in Taiwan, a vital ecological hotspot within the East Asian-Australasian Flyway, faces significant threats from anthropogenic activities, agricultural runoff, and climate variability. This study integrated multiple analytical approaches, including Hierarchical Cluster Analysis (HCA), Canonical Correspondence Analysis (CCA), and Generalized Additive Mixed Models (GAMMs), to investigate the spatial and temporal variability of phytoplankton communities across six sites over an eight-year monitoring period (2015–2023). Phytoplankton diversity, assessed using Shannon–Wiener and Margalef indices, revealed distinct patterns driven by environmental gradients, with diversity indices ranging from 0.06 (DS2, May) to 2.21 (CS, July). HCA grouped sites into distinct clusters based on nutrient dynamics and salinity, indicating the influence of site-specific conditions. CCA identified ammonia (NH₄-N), nitrate (NO₃-N), temperature, and salinity as the most significant environmental drivers affecting genera-level distributions. GAMM analyses further quantified nonlinear interactions between phytoplankton abundance and key parameters, such as total dissolved solids (TDS), total phosphorus (TP), NH₄-N, and NO₃-N, providing detailed insights into how these factors vary across seasons and sites. The dominance of Cyanobacteria during colder months, with an average winter temperature of 27.8 °C, indicates the heightened risk of harmful algal blooms associated with nutrient enrichment. Seasonal dynamics showed that warmer summer months intensified the effects of nitrate and total phosphorus, driving site-specific phytoplankton proliferation. Adaptive wetland management strategies, including enhanced hydrological connectivity, nutrient runoff reduction, and targeted restoration, are essential to mitigate eutrophication and sustain ecological resilience. This approach provided practical insights for balancing conservation goals with ecosystem services in one of Taiwan’s key wetlands.</p></div>","PeriodicalId":808,"journal":{"name":"Water, Air, & Soil Pollution","volume":"236 3","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143521588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficient acousto-optically Q-switched Tm: LuAG laser end-pumped by a laser diode at 1.7 μm","authors":"Wensheng Zhang,&nbsp;Linjun Li,&nbsp;Hong Liang","doi":"10.1007/s00340-025-08432-z","DOIUrl":"10.1007/s00340-025-08432-z","url":null,"abstract":"<div><p>We reported an efficient continuous-wave (CW) and acousto-optically (AO) Q-switched Tm: LuAG laser at 2 μm in-band pumped by a 1.7-µm laser diode for the first time. A maximum CW output power of 7.26 W at 2013 nm was achieved with an incident pump power of 28.2 W, corresponding to a slope efficiency of 38.5% and optical efficiency of 25.6%. With a repetition rate of 1 kHz, a maximum pulse energy of 5.63 mJ and a minimum pulse width of 77 ns were achieved under AO Q-switching regime, corresponding to a calculating peak power of 73.1 kW. Moreover, the M²-factors in x- and y-directions were measured to be about 1.9 and 1.7 at maximum output power, respectively.</p></div>","PeriodicalId":474,"journal":{"name":"Applied Physics B","volume":"131 3","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143521630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Amentoflavone Induces Ferroptosis to Alleviate Proliferation, Migration, Invasion and Inflammation in Rheumatoid Arthritis Fibroblast-like Synoviocytes by Inhibiting PIN1.","authors":"Yan Ma, Hongjun Lin, Yunman Li, Zhuoling An","doi":"10.1007/s12013-024-01563-8","DOIUrl":"10.1007/s12013-024-01563-8","url":null,"abstract":"<p><p>Rheumatoid arthritis (RA) is a systemic autoimmune disease that is prevalent worldwide and seriously threatens human health. RA-fibroblast-like synoviocytes (FLS) play important roles in almost all aspects of RA progression. This study aimed to study the effect of Amentoflavone (AMF), a polyphenol compound derived from extracts of Selaginella tamariscina, on the abnormal biological behaviors of RA-FLS. The immortalized human RA-FLS cell line (MH7A) was treated with AMF or transfected with small interfering RNAs (siRNAs) targeting peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1). Then, cell viability was detected by CCK-8 assay. EDU staining, wound healing and transwell assays were employed to measure the capacities of MH7A cell proliferation, migration and invasion. The levels of inflammatory factors were assessed using ELISA kits. Additionally, ferroptosis was analyzed by detecting Fe²⁺ content, lipid reactive oxygen species (ROS) level and expression of ferroptosis-related proteins. Pull-down assay was employed to verify the targeted binding of AMF to PIN1. Further, PIN1 overexpression or ferroptosis inhibitor Ferrostatin-1 (Fer-1) addition was conducted to elucidate the regulatory mechanism of AMF on PIN1 and ferroptosis. Results revealed that AMF intervention or PIN1 knockdown inhibited the proliferation, migration, invasion and inflammation in MH7A cells. AMF facilitated lipid peroxidation and ferroptosis in MH7A cells. Moreover, AMF targeted inhibition of PIN1 expression, and PIN1 overexpression restored the promoting effect of AMF on lipid peroxidation and ferroptosis in MH7A cells. Besides, Fer-1 reversed the impacts of AMF on the abnormal biological behaviors of MH7A cells. In summary, AMF induced ferroptosis to inhibit the proliferation, migration, invasion and inflammation in RA-FLS by inhibiting PIN1, providing a promising candidate for RA treatment.</p>","PeriodicalId":510,"journal":{"name":"Cell Biochemistry and Biophysics","volume":" ","pages":"1299-1312"},"PeriodicalIF":1.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142360885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Anti-proliferative Effect, Apoptotic Induction, and Cell Cycle Arrest of Tetra Halo Ruthenate Nanocomposites in Different Human Cancer Cell Lines.","authors":"Mariam Fathy, Salwa M El-Hallouty, Ahmed S Mansour, Mohamed Fahmy, Nourhan Hassan, Emad M ElZayat","doi":"10.1007/s12013-024-01519-y","DOIUrl":"10.1007/s12013-024-01519-y","url":null,"abstract":"<p><p>Chemotherapy is the most common cancer treatment, and metallic anticancer compounds have generated increasing amounts of interest since the discovery of cisplatin. More recently, scientists have focused on ruthenium-based compounds as alternatives for platinum compounds, which seem like ideal therapeutic anticancer alternatives to platinum derivatives. The present study aims to assess whether one or more of three Ruthenium-based nanocomposites, namely Ru+Lysine+CTAB (RCTL), Ru+CTAB (RCT), and Ru+Lysine (RL) exhibit pronounced anti-proliferative properties against different cancer cells. Three Ruthenium nanocomposites have been synthesized by standard chemical methods and characterized by Dynamic light scattering (DLS) and Transmission electron microscopy (TEM). The cytotoxic effect of the three composites has been evaluated by MTT in-vitro assay for different human cancer cell lines, namely MCF7, HepG2, A549, and PC3 versus normal human skin cell line (BJ1). The molecular underlying mechanisms of cytotoxicity have been assessed via qRT-PCR for pro-apoptotic makers P53 and Casp-3, and anti-apoptotic marker Bcl-2 as well as flow cytometric analysis of the cell cycle. Among the 3 nanocomposites, RCTL gave the best sensitivity and cytotoxicity especially on HepG2 with IC₅₀ 0.55 µg/ml but was still toxic on normal cell line with dose <12.5 µg/ml. RCTL and RCT nanocomposites have demonstrated a significant increase in the expression of P53 and Casp-3 markers versus untreated controls, but a significant reduction in the expression of Bcl-2. There was a direct correlation between the cytotoxic effect and the degree of apoptosis in the different cancer cell lines. The present study has also proved cell cycle arrest at G2-M and pre-G1 phases under the effect of IC₅₀ of RCTL and RCT nanocomposites in different cancer lines with the best effect being achieved in HepG2 cells. Ruthenium nanocomposites seem to open a new avenue in cancer therapy.</p>","PeriodicalId":510,"journal":{"name":"Cell Biochemistry and Biophysics","volume":" ","pages":"865-877"},"PeriodicalIF":1.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of TRAIL and SAHA Co-Treatment on Leukemia K562 Cell Line.","authors":"Amirarsalan Alaei, Saeed Solali, Masoud Mohammad Mirzapour","doi":"10.1007/s12013-024-01543-y","DOIUrl":"10.1007/s12013-024-01543-y","url":null,"abstract":"<p><p>TRAIL (Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand) is an attractive agent being considered a potential cancer treatment. It attaches to its death receptors, leading many cancer cells to apoptosis. However, some malignancies indicate substantial resistance to TRAIL, challenging anticancer scientists. Herein, combination therapy with TRAIL plus SAHA (Suberoyl Anilide Hydroxamic Acid) was conducted to evaluate the capability of SAHA to overcome TRAIL resistance in the leukemia K562 cell line. First, the IC₅₀ for SAHA was calculated (2 µM) at 12, 24, 48, and 72 h of treatment using MTT assay. Second, the K562 cells were treated with concentrations of 50 and 100 nM of TRAIL and 2 μM of SAHA separately and together for 24, 48, and 72 h and the survival of these cells was evaluated by Flowcytometry following the annexin-V and PI staining. To demonstrate the non-toxicity of the combined treatment for normal cells, the HEK-293 cell line was treated with the TRAIL 100 nM and SAHA 2 μM combined and separated at the same periods. In the end, by performing real-time PCR, the amount of candidate genes' expression implicated in TRAIL resistance, and the levels of BCR-ABL expression was measured. The drug dosages were not toxic to normal cells. SAHA plus TRAIL strongly triggered apoptosis in K562 cells after 24, 48, and 72 h of exposure. Furthermore, it was shown that DR4, DR5, and CHOP expressions were enhanced, and PI3K, Akt, ERK, STAT3, c-FLIPL, NF-κB, and BCR-ABL expressions were decreased by SAHA in K562 cells. Our study indicated that SAHA combined with TRAIL can increase the sensitivity of K562 leukemic cells to TRAIL by suppressing intracellular anti-apoptotic molecules and augmenting the expressions of DR4/DR5 and CHOP.</p>","PeriodicalId":510,"journal":{"name":"Cell Biochemistry and Biophysics","volume":" ","pages":"1087-1096"},"PeriodicalIF":1.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142399019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CKIP-1 inhibits M2 macrophage polarization to suppress the progression of gastric cancer by inactivating JAK/STAT3 signaling.","authors":"Xuefeng Xu, Zihong Xu, Yaowu Cai, Xintong Chen, Chaoqing Huang","doi":"10.1007/s12013-024-01562-9","DOIUrl":"10.1007/s12013-024-01562-9","url":null,"abstract":"<p><p>Gastric cancer (GC) is a frequently occurring malignancy with poor prognosis. Casein kinase 2 interacting protein-1 (CKIP-1) is a PH domain-containing protein implicated in regulating tumorigenesis and macrophage homeostasis. This study aimed to elucidate the role and potential mechanism of CKIP-1 in the progression of GC. CKIP-1 expression in GC tumor and para-carcinoma tissues was detected using RT-qPCR. Then, human monocyte cell line THP-1 was treated with PMA, interleukin (IL)-4 and IL-13 to induce M2-polarized macrophages. CD206, arginase-1 (Arg-1) and transforming growth factorβ1 (TGFβ1) expression in M2-polarized macrophages with or without CKIP-1 overexpression was evaluated. Moreover, GC cell lines (MKN45 and HGC27 cells) were co-cultured with CKIP-1-overexpressed M2-polarized macrophages, and the viability, migration and invasion of GC cells were measured. Additionally, immunoblotting assessed the expression of JAK/STAT3 signaling-related proteins and STAT3 agonist Colivelin was used to treat GC cells to perform the rescue experiments to analyze the changes of malignant phenotypes of GC cells. Results showed that CKIP-1 was downregulated in GC tissues and M2-polarized macrophages. CKIP-1 overexpression inhibited M2 macrophage polarization and decreased TGFβ1 secretion. Besides, elevated CKIP-1 expression in M2-polarized macrophages inhibited the viability, migration and invasion of GC cells. Furthermore, CKIP-1 overexpression inactivated JAK2/STAT3 signaling in GC cells by inhibiting TGFβ1 level. Specifically, Colivelin treatment abrogated the influences of CKIP-1 upregulation on the malignant phenotypes of GC cells. Collectively, CKIP-1 inhibits M2 macrophage polarization to suppress the progression of GC by inactivating JAK/STAT3 signaling pathway.</p>","PeriodicalId":510,"journal":{"name":"Cell Biochemistry and Biophysics","volume":" ","pages":"1289-1298"},"PeriodicalIF":1.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142542751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}