Analytical Methods最新文献

Designing a locally produced DENV-1 nucleic acid diagnostic for low resource regions with endemic disease. 设计一种地方性疾病低资源地区本地生产的DENV-1核酸诊断方法。

IF 2.6 3区化学

Analytical Methods Pub Date : 2025-10-15 DOI: 10.1039/d5ay00889a

Adam Roberts, Dushanth Seevaratnam, Ferguie B Solis, Maria Rhona G Bergantin, Dharmatov Rahula B Albano, Fortunato B Sevilla, Elizabeth A H Hall

{"title":"Designing a locally produced DENV-1 nucleic acid diagnostic for low resource regions with endemic disease.","authors":"Adam Roberts, Dushanth Seevaratnam, Ferguie B Solis, Maria Rhona G Bergantin, Dharmatov Rahula B Albano, Fortunato B Sevilla, Elizabeth A H Hall","doi":"10.1039/d5ay00889a","DOIUrl":"https://doi.org/10.1039/d5ay00889a","url":null,"abstract":"Using recombinant techniques, to support local production and availability of active diagnostic ingedients (ADIs) in regions with endemic or neglected disease, a reverse transcriptase (RT) fusion construct is reported (Δ3R5-TGP-RT), having the same modular architecture (R5-fluorescent protein-functional enzyme) as reported previously by us. In tandem with the R5-mCherry-Bst this RT construct completes the enzyme set required for RT-LAMP mediated detection of Dengue. The introduction of the thermophilic green fluorescence protein TGP, allowed a heat purification step at 95 °C to be introduced into the workflow, simplifying purification. A 3 terminal amino acid (SSK) truncation of the naturally occurring silaffin R5 binding peptide (Δ3R5) enabled improved protein purification and loading on silica and good storage stabilisation (≥3 months). L-arginine triggered elution of enzyme from silica, immediately prior to use, enabled a soluble enzyme to be delivered directly into the RT-LAMP reactions, producing a clear solution and compatibility with turbidity detection of PPi released complexes that form insoluble Mg2P2O7. A unique primer set was designed for the detection of Dengue Serotype 1 RNA, using a primer set (CAB 3), targeting the RNA-dependent RNA polymerase (RdRp), part of the NS5 region. This was chosen to minimise primer dimer formation, thereby reducing false positives. Amplification was achieved with high sensitivity (10 copies), with turbidity analysis able to distinguish positive and negative reactions. The approach developed has the potential to widen the application of LAMP diagnostics for neglected diseases such as Dengue by removing the availability of biological reagents as a limiting factor.","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145290349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Carvedilol microemulsion-loaded oleogel: development and validation via an HPLC method, identification of three degradation products, and toxicity prediction. 卡维地洛微乳负载油凝胶：高效液相色谱法的开发和验证，三种降解产物的鉴定和毒性预测。

IF 2.6 3区化学

Analytical Methods Pub Date : 2025-10-15 DOI: 10.1039/d5ay01393c

Ibtihal Abuhamdeh, Rania Hamed, Rima Hajjo, Nancy Sowan, Kamal Sweidan

{"title":"Carvedilol microemulsion-loaded oleogel: development and validation via an HPLC method, identification of three degradation products, and toxicity prediction.","authors":"Ibtihal Abuhamdeh, Rania Hamed, Rima Hajjo, Nancy Sowan, Kamal Sweidan","doi":"10.1039/d5ay01393c","DOIUrl":"https://doi.org/10.1039/d5ay01393c","url":null,"abstract":"In this work, carvedilol (CARV) was formulated as a microemulsion-loaded oleogel (CARV-MEOG) to enhance its solubility. An HPLC analytical method was developed and validated for assay, content uniformity, and dissolution tests. The mobile phase was composed of a 55 : 45 (v/v) mixture of 0.015 M phosphate buffer, adjusted to pH 2.7 ± 0.05, and acetonitrile, with its flow rate set at 1.2 mL min-1. The separation was conducted using Luna C18 (250 × 4.6) mm, 5 μm column at 35 °C and a wavelength of 240 nm. The injection volumes were 10 μL for the assay and content uniformity study and 100 μL for the dissolution studies. Validation was carried out in accordance with the ICH Q2(R1) guidelines. The method proved to be precise, rugged, accurate, selective, specific, and linear in the concentration range of 13.0-30.0 μg mL-1 for assay and content uniformity and 0.21-34.0 μg mL-1 for dissolution studies. In the assay, the forced degradation of CARV, CARV-MEOG, and excipients under stress conditions revealed three major degradants with well-resolved peaks, with RRT of 1.4, 3.7, and 4.2, respectively. The molecular masses of the observed degradants were determined using LC/MS, and their chemical structures were proposed. ADMET analysis showed that degradant 1 exhibits altered permeability and genotoxicity (AMES toxic), while degradants 2 and 3 retain similar pharmacokinetics to CARV.","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145290373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Leveraging R for advanced interpretation of LDI-TOF mass spectra: a computational approach. 利用R进行LDI-TOF质谱的高级解释：一种计算方法。

IF 2.6 3区化学

Analytical Methods Pub Date : 2025-10-15 DOI: 10.1039/d5ay01246e

Lubomír Prokeš, Lukáš Pečinka

引用次数: 0

A synergistic polyimide-silver nanowire interface enables simultaneous electrochemical detection of nitrophenol isomers. 协同聚酰亚胺-银纳米线界面可以同时进行硝基苯酚异构体的电化学检测。

IF 2.6 3区化学

Analytical Methods Pub Date : 2025-10-15 DOI: 10.1039/d5ay01293g

Zuhang Ding, Jianzheng Wang, Jing Jin, Minjie Guo, Qinran Li, Zhi Fan, Jin Zhao

{"title":"A synergistic polyimide-silver nanowire interface enables simultaneous electrochemical detection of nitrophenol isomers.","authors":"Zuhang Ding, Jianzheng Wang, Jing Jin, Minjie Guo, Qinran Li, Zhi Fan, Jin Zhao","doi":"10.1039/d5ay01293g","DOIUrl":"https://doi.org/10.1039/d5ay01293g","url":null,"abstract":"This research describes a novel electrochemical sensor based on a polyimide-silver nanowire (PI-AgNW) composite that is used to modify a glassy carbon electrode (GCE) for the simultaneous detection of multiple nitrophenol isomers (NPs) with high performance. The synergistic effect of polyimide (PI) doped silver nanowires (AgNWs) improved the selectivity and sensitivity of the fabricated sensor. First, the AgNWs were prepared by the polyol process, and then composited with PI to obtain the target composite. Subsequently, the composite was characterized in detail and was used to modify a GCE for the NP detection. Afterwards, electrochemical measurements were performed for simultaneous detection of three NPs. Under optimal conditions, the results showed that the linear detection ranges were 1-400 μM for 4-nitrophenol (4-NP) and 1-350 μM for both 2-nitrophenol (2-NP) and 3-nitrophenol (3-NP) and the limits of detection (LODs) were 0.081 μM for 2-NP, 0.107 μM for 3-NP, and 0.063 μM for 4-NP, respectively. In addition, the fabricated electrode exhibited excellent reproducibility (RSDs of 2.85% for 2-NP, 2.71% for 3-NP, and 1.80% for 4-NP, respectively) and stability (RSDs of 6.17% for 2-NP, 2.36% for 3-NP, and 3.89% for 4-NP, respectively) over multiple measurements. Moreover, the sensor showed excellent anti-interference capability and was successfully applied to detect NP analytes in real water samples with recoveries ranging from 91.10% to 109.00%. This study emphasizes the potential application of PI-AgNW composites for the rapid detection of NPs in the environment.","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145290355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Demonstrating the application of a liquid chromatography-mass spectrometry method for the determination of phthalate diesters in complex solid and liquid environmental samples. 演示了液相色谱-质谱法测定复杂固体和液体环境样品中邻苯二甲酸酯二酯的应用。

IF 2.6 3区化学

Analytical Methods Pub Date : 2025-10-15 DOI: 10.1039/d5ay01057h

Fiona Regan, Catherine Allen, Jenny Lawler

{"title":"Demonstrating the application of a liquid chromatography-mass spectrometry method for the determination of phthalate diesters in complex solid and liquid environmental samples.","authors":"Fiona Regan, Catherine Allen, Jenny Lawler","doi":"10.1039/d5ay01057h","DOIUrl":"https://doi.org/10.1039/d5ay01057h","url":null,"abstract":"Phthalate diesters are ubiquitous contaminants of concern, yet their reliable determination in complex environmental matrices remains analytically challenging due to low environmental concentrations, matrix interferences, and widespread background contamination. Here, we present a robust LC-MS/MS workflow for the simultaneous quantification of eleven low- and high-molecular weight phthalates across four contrasting matrices: surface water, landfill leachate, soils, and municipal solid wastes. Sample preparation was streamlined using ultrasonication or filtration followed by solid-phase extraction (SPE), providing recoveries of 70-98% without the need for derivatisation. The method delivered sub-ng L-1 detection limits (as low as 0.2 ng L-1) and high reproducibility (RSD <5%), while integrated contamination-control strategies, including delay columns and phthalate-free materials, enabled reliable trace analysis. Systematic evaluation of matrix effects confirmed robustness across diverse environmental samples. This method combines sensitivity, selectivity, and broad applicability, offering a practical platform for routine environmental monitoring of phthalates at trace levels.","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145290397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A highly sensitive electrochemiluminescence immunosensor based on Ru(bpy)₃²⁺/PAMG composite carriers and Au-Fc-MOF quenching systems for ultra-trace detection of carcinoembryonic antigen. 基于Ru(bpy)32+/PAMG复合载体和Au-Fc-MOF猝灭体系的高灵敏度电化学发光免疫传感器用于癌胚抗原超痕量检测。

IF 2.6 3区化学

Analytical Methods Pub Date : 2025-10-15 DOI: 10.1039/d5ay01289a

Baohan Wen, Haoyi Ren, Wenjing Lai, Min Wang, Mingzhe Jiang, Yingying Cheng, Yige Li, Chenglin Hong, Yu Qi

{"title":"A highly sensitive electrochemiluminescence immunosensor based on Ru(bpy)32+/PAMG composite carriers and Au-Fc-MOF quenching systems for ultra-trace detection of carcinoembryonic antigen.","authors":"Baohan Wen, Haoyi Ren, Wenjing Lai, Min Wang, Mingzhe Jiang, Yingying Cheng, Yige Li, Chenglin Hong, Yu Qi","doi":"10.1039/d5ay01289a","DOIUrl":"https://doi.org/10.1039/d5ay01289a","url":null,"abstract":"Early cancer diagnosis is crucial due to a significant increase in cancer incidence over the last three decades. A highly sensitive electrochemiluminescence technique was developed for carcinoembryonic antigen (CEA) detection. This method uses Ru(bpy)32+ as the luminescent substance and a silica and polyacrylamide gel composite as the carrier. Ru(bpy)32+ is loaded into it to prevent its leakage. At the same time, biological molecules such as antibodies or antigens are immobilized, thereby improving the stability and reaction activity of the system. Additionally, Au-Fc-MOF was synthesized to act as a quencher and secondary antibody label, absorbing the emitted energy from the ECL emitter to improve detection accuracy across various CEA concentrations. Potassium persulfate was employed as a co-reactant to generate SO4˙- radicals, intensifying the luminescence output of the system. The findings revealed that the developed immunosensor exhibited strong linearity within the concentration range of 10-5 ng mL-1 to 10 ng mL-1, with a remarkably low detection limit of 5.03 fg mL-1. This electrochemical luminescence immunosensor, characterized by its simple preparation, cost-effectiveness, and superior performance, demonstrates significant potential in advancing early CEA detection methodologies.","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145290379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A quantitative prediction strategy for UV-vis spectroscopy of nitrate in water based on a difference spectrum-hybrid prediction model. 基于差谱-混合预测模型的水中硝酸盐紫外-可见光谱定量预测策略

IF 2.6 3区化学

Analytical Methods Pub Date : 2025-10-14 DOI: 10.1039/d5ay01268f

Xin Wang, Qiaoling Du, Hongmei Wang

{"title":"A quantitative prediction strategy for UV-vis spectroscopy of nitrate in water based on a difference spectrum-hybrid prediction model.","authors":"Xin Wang, Qiaoling Du, Hongmei Wang","doi":"10.1039/d5ay01268f","DOIUrl":"https://doi.org/10.1039/d5ay01268f","url":null,"abstract":"Due to spectral influence caused by turbidity, the accuracy of nitrate quantification using UV-vis spectroscopy remains challenging. This study proposes an integrated method combining UV-vis spectroscopy, difference spectrum analysis, and a hybrid prediction model to address this issue. By analyzing the linear relationship between the difference spectrum and turbidity, a novel turbidity compensation strategy-the Mixed Difference Nitrate Method (MDNM)-was developed. Subsequently, a hybrid prediction framework integrating linear regression and threshold-based waveband selection was employed to enhance modeling accuracy. Experimental results on both standard and natural water samples demonstrate that the method achieves high accuracy and generalization ability, with an R2 of 0.9982 and an RMSE of 0.2629 mg L-1 for standard samples, and an R2 of 0.9663 and an RMSE of 0.7835 mg L-1 for natural water samples. The proposed method offers a simple, effective, and low-cost strategy for nitrate detection in turbid water, with significant potential for practical environmental monitoring and water quality assessment.","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145285100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent advances in the application of ion resonance methods in ion trap mass spectrometers. 离子共振方法在离子阱质谱中的应用进展。

IF 2.6 3区化学

Analytical Methods Pub Date : 2025-10-14 DOI: 10.1039/d5ay01078k

Gangnan Chen, Zhiwei Wang, Haoqiang Yan, Ang Li, Renbiao Xie, Dayu Li

{"title":"Recent advances in the application of ion resonance methods in ion trap mass spectrometers.","authors":"Gangnan Chen, Zhiwei Wang, Haoqiang Yan, Ang Li, Renbiao Xie, Dayu Li","doi":"10.1039/d5ay01078k","DOIUrl":"https://doi.org/10.1039/d5ay01078k","url":null,"abstract":"Recent years have witnessed remarkable advances in ion resonance method design for ion trap mass spectrometers, especially in the context of instrument miniaturization. These developments aim to enhance ion selectivity, fragmentation efficiency, and scanning performance without altering the mechanical structure of the device. In the field of ion isolation, a series of waveform innovations-such as Grid-SWIFT, SWIFTSIN, and SAM-SFM-have been introduced to improve resolution, sensitivity, and computational efficiency. Real-time waveform synthesis strategies have further simplified implementation on portable platforms. For collision-induced dissociation (CID), techniques such as orthogonal excitation and repetitive frequency sweeps have enabled two-dimensional mass spectrometry on compact systems, allowing correlation between precursor and product ions and enriching the dimensionality of dissociation information in both time and frequency domains. In terms of ion scanning, innovations in voltage and frequency scan methods have significantly expanded the detectable mass range and improved mass resolution. Furthermore, the integration of ion mobility analysis with resonance excitation has enabled ultra-high-resolution separation of isomers and chiral compounds. These advancements collectively demonstrate the crucial role of ion resonance methods in overcoming the performance limitations of miniature ion trap mass spectrometers and open up new possibilities for their future development.","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145285039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of portable equipment based on computer vision and colorimetric assays to measure the biodiesel content in BX diesel. 基于计算机视觉和比色法测定BX柴油中生物柴油含量的便携式设备的研制。

IF 2.6 3区化学

Analytical Methods Pub Date : 2025-10-13 DOI: 10.1039/d5ay01251a

Rafael S Xavier, Thiago S Dias, Débora F de Andrade, Daniella L Vale, Cristiane G de Souza, Luiz Antonio d'Avila

{"title":"Development of portable equipment based on computer vision and colorimetric assays to measure the biodiesel content in BX diesel.","authors":"Rafael S Xavier, Thiago S Dias, Débora F de Andrade, Daniella L Vale, Cristiane G de Souza, Luiz Antonio d'Avila","doi":"10.1039/d5ay01251a","DOIUrl":"https://doi.org/10.1039/d5ay01251a","url":null,"abstract":"This study presents a low-cost, 3D-printed portable device that integrates computer vision and an artificial neural network (ANN) to quantify biodiesel content (1-30% v/v) in fossil diesel blends using a solvatochromic assay with Reichardt's dye. A total of 105 samples (35 biodiesel blend levels in triplicate) were analyzed with both the proposed method and the official Brazilian standard ABNT NBR 15568/2008 (FT-IR). While the standard method requires laboratory infrastructure and specialized equipment, the proposed system provides comparable accuracy directly at the point of fuel distribution. It achieved a mean absolute error (MAE) of 1.5% (R2 = 0.969) for training data and 0.5% (R2 = 0.995) for independent test data. Robust cross-validation confirmed model stability and absence of overfitting, and a paired Student's t-test showed no statistically significant difference between the two methods (p > 0.05), confirming statistical equivalence. Beyond analytical performance, the device offers practical advantages: controlled lighting and webcam-based image acquisition coupled with ANN processing enable rapid, on-site biodiesel determination without specialized training. This contrasts with the official method, which is restricted to laboratory settings. By combining portability, low operational complexity, and real-time analysis capability, this system represents a significant advancement for fuel quality monitoring, allowing reliable control of BX diesel blends directly at fueling stations and other non-laboratory environments. BX diesel, dye solution, and ethanol.","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145278503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extraction, recovery, and biological activity evaluation of triterpenoids from Prunella vulgaris L. using ultrasound-assisted green solvents. 超声波辅助绿色溶剂提取、回收夏枯草中三萜及其生物活性评价。

IF 2.6 3区化学

Analytical Methods Pub Date : 2025-10-13 DOI: 10.1039/d5ay00433k

Nhan Trong Le, Vi Thuy Thi Nguyen, Khan Viet Nguyen, Duc Viet Ho, Huong Thanh Phung, Hoai Thi Nguyen

{"title":"Extraction, recovery, and biological activity evaluation of triterpenoids from Prunella vulgaris L. using ultrasound-assisted green solvents.","authors":"Nhan Trong Le, Vi Thuy Thi Nguyen, Khan Viet Nguyen, Duc Viet Ho, Huong Thanh Phung, Hoai Thi Nguyen","doi":"10.1039/d5ay00433k","DOIUrl":"https://doi.org/10.1039/d5ay00433k","url":null,"abstract":"Using green solvents to extract bioactives from medicinal herbs is a sustainable development trend. This research sought to extract and assess the bioactivities of triterpenoids from Prunella vulgaris using green solvents with ultrasound assistance. The green solvents were carefully selected, and the betaine-lactic acid solvent provided the best extraction efficiency. The extraction procedure was meticulously optimized using a combination of Plackett-Burman and Box-Behnken designs. Triterpenoids were recovered by solid-liquid extraction with macroporous resins, with D-101 and AB-8 resins being the two resins that provided the best recovery efficiency. Both green solvents and resins were successfully reused for at least three cycles of extraction and recovery. Triterpenoids extracted using green solvents exhibited superior cytotoxic, α-glucosidase inhibitory, and antimicrobial activities compared to those extracted with organic solvents. The comprehensive results of this study confirm the significant role of green solvents in extracting high-value compounds from biomass, promoting further large-scale studies toward sustainable development.","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145278510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0