{"title":"Downward movement of nitrate stimulates losses of soil organic carbon in deeper soil layers.","authors":"Xiaotang Ju, Chong Zhang, Xue Tian","doi":"10.1073/pnas.2510350122","DOIUrl":"https://doi.org/10.1073/pnas.2510350122","url":null,"abstract":"","PeriodicalId":20548,"journal":{"name":"Proceedings of the National Academy of Sciences of the United States of America","volume":"122 27","pages":"e2510350122"},"PeriodicalIF":9.4,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144289669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reply to Ju et al.: Mechanisms of deeper soil organic carbon loss.","authors":"Zhenghu Zhoua, Minggang Xu, Andong Cai","doi":"10.1073/pnas.2510690122","DOIUrl":"https://doi.org/10.1073/pnas.2510690122","url":null,"abstract":"","PeriodicalId":20548,"journal":{"name":"Proceedings of the National Academy of Sciences of the United States of America","volume":"122 27","pages":"e2510690122"},"PeriodicalIF":9.4,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144289670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to Supporting Information for Bardy et al., Neuronal medium that supports basic synaptic functions and activity of human neurons in vitro.","authors":"","doi":"10.1073/pnas.2512898122","DOIUrl":"https://doi.org/10.1073/pnas.2512898122","url":null,"abstract":"","PeriodicalId":20548,"journal":{"name":"Proceedings of the National Academy of Sciences of the United States of America","volume":"122 26","pages":"e2512898122"},"PeriodicalIF":9.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144289664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jibril B Hirbo, Martin C Were, Celestial R Jones-Paris
{"title":"On the relationship between genes and environment.","authors":"Jibril B Hirbo, Martin C Were, Celestial R Jones-Paris","doi":"10.1073/pnas.2510804122","DOIUrl":"https://doi.org/10.1073/pnas.2510804122","url":null,"abstract":"","PeriodicalId":20548,"journal":{"name":"Proceedings of the National Academy of Sciences of the United States of America","volume":"122 26","pages":"e2510804122"},"PeriodicalIF":9.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144289665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marcus Clauss, Marco Roller, Mads F Bertelsen, Claudia Rudolf von Rohr, Dennis W H Müller, Christian Schiffmann, Maya Kummrow, Dag Encke, Sam Ferreira, Ethan S Duvall, Celesté Maré, Andrew J Abraham
{"title":"Reply to Ferraro et al.: Breed-and-feed reflects inevitable trade-offs between individual longevity and population sustainability.","authors":"Marcus Clauss, Marco Roller, Mads F Bertelsen, Claudia Rudolf von Rohr, Dennis W H Müller, Christian Schiffmann, Maya Kummrow, Dag Encke, Sam Ferreira, Ethan S Duvall, Celesté Maré, Andrew J Abraham","doi":"10.1073/pnas.2509145122","DOIUrl":"https://doi.org/10.1073/pnas.2509145122","url":null,"abstract":"","PeriodicalId":20548,"journal":{"name":"Proceedings of the National Academy of Sciences of the United States of America","volume":"122 26","pages":"e2509145122"},"PeriodicalIF":9.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144289667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kristy M Ferraro, Anthony L Ferraro, Julia D Monk, Elizabeth S Forbes
{"title":"Outdated reproductive norms, the naturalistic fallacy, and misunderstandings of welfare in recent call for zoo breed-and-feed programs.","authors":"Kristy M Ferraro, Anthony L Ferraro, Julia D Monk, Elizabeth S Forbes","doi":"10.1073/pnas.2504225122","DOIUrl":"https://doi.org/10.1073/pnas.2504225122","url":null,"abstract":"","PeriodicalId":20548,"journal":{"name":"Proceedings of the National Academy of Sciences of the United States of America","volume":"122 26","pages":"e2504225122"},"PeriodicalIF":9.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144289666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xin-Rui Wu, Liu Yang, Bang-Sheng Wu, Wei Cheng, Jin-Tai Yu
{"title":"Reply to Hirbo et al.: The need for large-scale family cohorts and robust analytical frameworks of postexome study.","authors":"Xin-Rui Wu, Liu Yang, Bang-Sheng Wu, Wei Cheng, Jin-Tai Yu","doi":"10.1073/pnas.2511041122","DOIUrl":"https://doi.org/10.1073/pnas.2511041122","url":null,"abstract":"","PeriodicalId":20548,"journal":{"name":"Proceedings of the National Academy of Sciences of the United States of America","volume":"122 26","pages":"e2511041122"},"PeriodicalIF":9.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144289668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction for Ewart et al., Relaxation to universal non-Maxwellian equilibria in a collisionless plasma.","authors":"","doi":"10.1073/pnas.2512776122","DOIUrl":"https://doi.org/10.1073/pnas.2512776122","url":null,"abstract":"","PeriodicalId":20548,"journal":{"name":"Proceedings of the National Academy of Sciences of the United States of America","volume":"122 26","pages":"e2512776122"},"PeriodicalIF":9.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144289663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction for Luo and Yu, NBS1 facilitates preribosomal RNA biogenesis.","authors":"","doi":"10.1073/pnas.2512482122","DOIUrl":"https://doi.org/10.1073/pnas.2512482122","url":null,"abstract":"","PeriodicalId":20548,"journal":{"name":"Proceedings of the National Academy of Sciences of the United States of America","volume":"122 25","pages":"e2512482122"},"PeriodicalIF":9.4,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144289657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vaishally, Sourajyoti Pal, Kedhar R Thyagarajan, Shantanu P Shukla
{"title":"An endosymbiotic origin of the crimson pigment from the lac insect.","authors":"Vaishally, Sourajyoti Pal, Kedhar R Thyagarajan, Shantanu P Shukla","doi":"10.1073/pnas.2501623122","DOIUrl":"https://doi.org/10.1073/pnas.2501623122","url":null,"abstract":"<p><p>Symbioses with microorganisms expand the genetic and metabolic repertoire of many insects. The lac insect <i>Kerria lacca</i> (Hemiptera: Sternorrhyncha) is a phloem-feeding scale insect that is brightly colored due to the presence of natural polyhydroxy-anthraquinone pigments called laccaic acids. The deep red pigments possibly provide defense against pathogens and predators and are commercially important as dyes in textiles, lacquerware, and cosmetics. Laccaic acids are categorized as polyketides comprising an anthraquinone backbone decorated with tyrosine or its derivatives. However, the genetic basis of these pigments remains unknown, as insects are not known to produce aromatic polyketides or tyrosine de novo. Here, we sequence the genome of the lac insect and its two endosymbionts-<i>Wolbachia</i> and a hitherto unidentified, transovarially transmitted yeast-like symbiont (YLS). We found no evidence for the host or <i>Wolbachia</i> to be able to synthesize the pigments. The pigments and their precursors were also not detected in the host plant. Genomic, transcriptomic, and metabolomic analyses combined with fluorescence microscopy identified and characterized YLS as the sole producer of the pigment's polyketide backbone and tyrosine moiety, demonstrating an endosymbiotic origin of the lac pigments. A nonreducing polyketide synthase gene cluster encoding the laccaic acid backbone was identified. Furthermore, the YLS genome encoded essential amino acids and vitamins that are deficient in the insect's phloem diet. Experimental fungicide-treated insects exhibited reduced concentrations of laccaic acids and tyrosine, along with decreased body size and weight, indicating a mutualistic association between the lac insect and its YLS.</p>","PeriodicalId":20548,"journal":{"name":"Proceedings of the National Academy of Sciences of the United States of America","volume":"122 25","pages":"e2501623122"},"PeriodicalIF":9.4,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144310409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}