综合性期刊最新文献

{"title":"Enantioselective sp3-sp3 cross-coupling of oxygen-containing heterocycles with cyclopropanols","authors":"Yang Ke,Huiyao Liu,Gaoyuan Yu,Yuanyuan Ping,Wangqing Kong","doi":"10.1038/s41467-026-78834-w","DOIUrl":"https://doi.org/10.1038/s41467-026-78834-w","url":null,"abstract":"","PeriodicalId":19066,"journal":{"name":"Nature Communications","volume":"16 1","pages":""},"PeriodicalIF":16.6,"publicationDate":"2026-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149210210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adma and Ackr3a regulate cardiac lymphatic vessel formation and function during heart development and regeneration","authors":"Xidi Feng,Hui-Yu Chen,Yuhan Sun,Fei Sun,Sean Yan,Subir Kapuria,Raquel Rodriguez,Laurent Gamba,J. Gage Crump,Young-Kwon Hong,Kenneth D. Poss,Ching-Ling Lien","doi":"10.1038/s41467-026-78353-8","DOIUrl":"https://doi.org/10.1038/s41467-026-78353-8","url":null,"abstract":"","PeriodicalId":19066,"journal":{"name":"Nature Communications","volume":"53 1","pages":""},"PeriodicalIF":16.6,"publicationDate":"2026-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149210213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optical-handedness-driven enantioselective synthesis and programmable chirality encoding of covalent organic frameworks","authors":"Taewoong Kim,Jaewon Kim,Joohee Oh,Seungyoon Kang,Song Gyun Kim,Jee Hyeon Kim,Min Su Han,Young Yong Kim,Chanho Pak,Jeong-Eun Park,Hyunseob Lim","doi":"10.1038/s41467-026-78524-7","DOIUrl":"https://doi.org/10.1038/s41467-026-78524-7","url":null,"abstract":"","PeriodicalId":19066,"journal":{"name":"Nature Communications","volume":"37 1","pages":""},"PeriodicalIF":16.6,"publicationDate":"2026-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149210221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A dataset on radical and extremist attitudes in Europe.","authors":"Sebastian Jungkunz, Nina Fadarkhan Osenbrügge, Marc Helbling","doi":"10.1038/s41597-026-08455-x","DOIUrl":"https://doi.org/10.1038/s41597-026-08455-x","url":null,"abstract":"<p><p>This dataset introduces the first cross-nationally validated measurement scales for left-wing and right-wing radicalism, and general political extremism, along with an implicit association test (IAT) for implicit political extremism in the Western world. It includes data from more than 18,000 participants collected through ten surveys conducted between 2022 and 2024 in France, Germany, Great Britain, Greece, Hungary, the Netherlands, and the United States. The dataset facilitates comparative analyses of the origins and consequences of radical and extremist attitudes across different political systems. Moreover, by linking attitudinal measures with behavioral indicators such as party support, it provides a foundation for examining how latent forms of extremism are translated into political action. Beyond extremism research, the dataset contributes to the broader study of democratic resilience, political polarization, and ideological belief structures.</p>","PeriodicalId":21597,"journal":{"name":"Scientific Data","volume":"13 1","pages":""},"PeriodicalIF":7.2,"publicationDate":"2026-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149216809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breaking water-structure constraints by Hofmeister effects in interfacial polymerization for polyamide membranes","authors":"Qingchen Tang,Hao Chen,Yu Chen,Hanyu Wu,Xingwang Meng,Wu Jin,Panjia Jiang,Yizhou Zhang,Xunda Feng","doi":"10.1038/s41467-026-78649-9","DOIUrl":"https://doi.org/10.1038/s41467-026-78649-9","url":null,"abstract":"Abstract Hydration critically governs the physicochemical behavior of solutes in both the aqueous bulk and interfacial environments. As typical chaotropic Hofmeister ions, weakly hydrated anions (WHAs) can reshape hydration structures and accumulate at water–hydrophobe interfaces. Notably, WHAs paradoxically suppress the solubility of certain small-molecule monomers in water while enhancing that of chemically analogous polymers. Here, we exploit WHA-mediated Hofmeister hydration control to regulate polyamide-forming interfacial polymerization (IP), using the piperazine (PIP) and trimesoyl chloride (TMC) nanofiltration system as the primary model. Introducing WHAs into the aqueous phase reduces the affinity of amine monomers for water and accelerates partitioning into the reaction front in the oil phase, remarkably reinforcing IP self-limitation. Simultaneously, interfacial WHA enrichment lowers interfacial tension and, together with accelerated amine delivery, potentially intensifies transport-driven interfacial instabilities. WHAs also lower interfacial water availability, attenuating acyl chloride hydrolysis. These synergistic effects yield hollow-ridged polyamide selective layers with reduced thickness and high crosslinking density, delivering enhanced water permeance and salt rejection. Crucially, module-scale fabrication of high-performance membranes demonstrates that WHA-mediated Hofmeister hydration control is directly compatible with established desalination pipelines.","PeriodicalId":19066,"journal":{"name":"Nature Communications","volume":"26 1","pages":""},"PeriodicalIF":16.6,"publicationDate":"2026-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149210215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coordinated control of both microtubule ends regulates mitotic spindle length","authors":"Shane A. Fiorenza,Sheba Cheeran,Elena Doria,Iva M. Tolić,Patrick Meraldi,Nenad Pavin","doi":"10.1038/s41467-026-78426-8","DOIUrl":"https://doi.org/10.1038/s41467-026-78426-8","url":null,"abstract":"Abstract The mitotic spindle is a biomechanical structure whose length must be precisely controlled to ensure faithful chromosome segregation. The treadmilling of microtubules towards spindle poles, termed poleward flux, is involved in spindle length control. However, poleward flux velocity has been shown to be both inversely and directly proportional to spindle length, a contradiction that remains unexplained by current mechanisms. Here we introduce a model which demonstrates that length-dependent regulation at both microtubule ends allows plus- and minus-end dynamics to synchronize with one another, enabling pathways of poleward-flux-based spindle length control which rectify previous results. Moreover, our model predicts that spindle length and poleward flux velocity can vary independently via simultaneous perturbations at both microtubule ends, which we validate with protein depletion experiments in human cells. Finally, we provide experimental evidence for length-dependent accumulation of proteins at microtubule minus-ends. Our results thus resolve a longstanding paradox and provide mechanistic insight into the reciprocal control of spindle length and poleward flux.","PeriodicalId":19066,"journal":{"name":"Nature Communications","volume":"33 1","pages":""},"PeriodicalIF":16.6,"publicationDate":"2026-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149210220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Permeability heterogeneity controls fluid migration and microseismicity evolution in The Geysers geothermal field, California","authors":"Lei Li,Xiaobao Zeng,Ian W. McBrearty,Xin Cui,Xing Tan,Shujuan Mao,Gregory C. Beroza,Jingqiang Tan,Jianxin Liu,Paul Segall,William L. Ellsworth","doi":"10.1038/s41467-026-78210-8","DOIUrl":"https://doi.org/10.1038/s41467-026-78210-8","url":null,"abstract":"","PeriodicalId":19066,"journal":{"name":"Nature Communications","volume":"38 1","pages":""},"PeriodicalIF":16.6,"publicationDate":"2026-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149210485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"De novo design of lipopeptides with antimicrobial potency enabled by a chain-as-prompt deep learning framework","authors":"Fan Zhang,Xuchang Yu,Yuzhu Wu,Lei Li","doi":"10.1038/s41467-026-78763-8","DOIUrl":"https://doi.org/10.1038/s41467-026-78763-8","url":null,"abstract":"","PeriodicalId":19066,"journal":{"name":"Nature Communications","volume":"53 1","pages":""},"PeriodicalIF":16.6,"publicationDate":"2026-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149210202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perk mediates tumor cell fate and therapeutic outcome in response to CDK4/6 inhibition","authors":"Marganit Farago,Bartosz Mucha,Varun Samudra,Shuyuan Zhang,Dariusz Pytel,Ata Abbas,Polly Phillips-Mason,Debora Cavero,Masataka Shimonosono,Brian S. Henick,Hiroshi Nakagawa,Kwok-Kin Wong,Anil K. Rustgi,Constantinos Koumenis,Davide Ruggero,Yi Fan,Serge Y. Fuchs,J. Alan Diehl","doi":"10.1038/s41467-026-78698-0","DOIUrl":"https://doi.org/10.1038/s41467-026-78698-0","url":null,"abstract":"","PeriodicalId":19066,"journal":{"name":"Nature Communications","volume":"42 1","pages":""},"PeriodicalIF":16.6,"publicationDate":"2026-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149210209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Confining chlorine in the cation solvation sheaths towards stable and sustainable seawater electrolysis","authors":"Peng-Cheng Yu,Ye-Hua Wang,Xiao-Long Zhang,Shu-Ping Sun,Tao Fang,Xu-Ying-Nan Tao,Yu Yang,Jie Liao,Ye-Cheng Li,Zhuang-Zhuang Niu,Mei Sun,Ming-Hui Fan,Shou-Jie Liu,Fei-Yue Gao,Min-Rui Gao","doi":"10.1038/s41467-026-78207-3","DOIUrl":"https://doi.org/10.1038/s41467-026-78207-3","url":null,"abstract":"Abstract Chlorine electro-oxidation represents the primary anode side reaction during direct seawater electrolysis, causing corrosion and permanent deactivation of catalyst and thereby insufficient stability. We report that in situ segregated fluorine can actuate the desolvation of cations and Cl − ions via strong H ∙ ∙ ∙ F bonding, leading to the formation of intimate cation-Cl − contact ion pairs that make Cl − migration toward electrode surface prohibited. Meanwhile, fluorine remaining in the cobalt-based catalyst shortens the Co–Co distance, attributable to its large electronegativity, triggering an oxide path mechanism that circumvents the nonideal scaling between OH * and OOH * during oxygen-evolving reaction. Direct seawater electrolysis (with 1 M NaOH) incorporating this catalyst achieves 1 ampere per square centimeter (A cm −2 ) at 1.7 volts and maintains at 0.5 A cm −2 and 60 °C over 2,450 hours degrading at 24.9 microvolts per hour. Our catalyst even survives repeatedly switched current densities (0.25, 0.5, and 1 A cm −2 ) for more than 1,250 hours, manifesting compatibility with fluctuating renewable electricity.","PeriodicalId":19066,"journal":{"name":"Nature Communications","volume":"73 1","pages":""},"PeriodicalIF":16.6,"publicationDate":"2026-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149210201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}