Journal of The Royal Society Interface最新文献

The suppression of ocean waves by biogenic slicks. 生物浮渣对海浪的压制。

IF 3.7 2区综合性期刊

Journal of The Royal Society Interface Pub Date : 2024-11-01 Epub Date: 2024-11-13 DOI: 10.1098/rsif.2024.0385

Nathan J M Laxague, Christopher J Zappa, Shantanu Soumya, Oliver Wurl

{"title":"The suppression of ocean waves by biogenic slicks.","authors":"Nathan J M Laxague, Christopher J Zappa, Shantanu Soumya, Oliver Wurl","doi":"10.1098/rsif.2024.0385","DOIUrl":"10.1098/rsif.2024.0385","url":null,"abstract":"Ocean waves are significantly damped by biogenic surfactants, which accumulate at the sea surface in every ocean basin. The growth, development, and breaking of short wind-driven surface waves are key mediators of the air-sea exchange of momentum, heat and trace gases. The mechanisms through which surfactants suppress waves have been studied in great detail through careful laboratory experimentation in quasi-one-dimensional wave tanks. However, the spatial scales over which this damping occurs in structurally complex surfactant slicks on the real ocean have not been resolved. Here, we present the results of field observations of the spatial response of decimetre- to millimetre-scale waves to biogenic surfactant slicks. We found that wave damping in organic material-rich coastal waters resulted in a net (spatio-temporally averaged) reduction of approximately 50% in wave slope variance relative to the open ocean for low to moderate wind speeds. This reduction of wave slope variance is understood to result in a corresponding reduction in momentum input to the wave field. This significant effect had thus far evaded quantification due in large part to the enormous range of scales required for its description-spanning the sea surface microlayer to the ocean submesoscale.","PeriodicalId":17488,"journal":{"name":"Journal of The Royal Society Interface","volume":"21 220","pages":"20240385"},"PeriodicalIF":3.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11557231/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142621268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Global and local identifiability analysis of a nonlinear biphasic constitutive model in confined compression. 约束压缩非线性双相构造模型的全局和局部可识别性分析

IF 3.7 2区综合性期刊

Journal of The Royal Society Interface Pub Date : 2024-11-01 Epub Date: 2024-11-13 DOI: 10.1098/rsif.2024.0415

John M Peloquin, Dawn M Elliott

{"title":"Global and local identifiability analysis of a nonlinear biphasic constitutive model in confined compression.","authors":"John M Peloquin, Dawn M Elliott","doi":"10.1098/rsif.2024.0415","DOIUrl":"10.1098/rsif.2024.0415","url":null,"abstract":"Application of biomechanical models relies on model parameters estimated from experimental data. Parameter non-identifiability, when the same model output can be produced by many sets of parameter values, introduces severe errors yet has received relatively little attention in biomechanics and is subtle enough to remain unnoticed in the absence of deliberate verification. The present work develops a global identifiability analysis method in which cluster analysis and singular value decomposition are applied to vectors of parameter-output variable correlation coefficients. This method provides a visual representation of which specific experimental design elements are beneficial or harmful in terms of parameter identifiability, supporting the correction of deficiencies in the test protocol prior to testing physical specimens. The method was applied to a representative nonlinear biphasic model for cartilaginous tissue, demonstrating that confined compression data does not provide identifiability for the biphasic model parameters. This result was confirmed by two independent analyses: local analysis of the Hessian of a sum-of-squares error cost function and observation of the behaviour of two optimization algorithms. Therefore, confined compression data are insufficient for the calibration of general-purpose biphasic models. Identifiability analysis by these or other methods is strongly recommended when planning future experiments.","PeriodicalId":17488,"journal":{"name":"Journal of The Royal Society Interface","volume":"21 220","pages":"20240415"},"PeriodicalIF":3.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11557236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142623197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cocoon microstructures through the lens of topological persistence. 通过拓扑持久性透视茧微结构

IF 3.7 2区综合性期刊

Journal of The Royal Society Interface Pub Date : 2024-11-01 Epub Date: 2024-11-13 DOI: 10.1098/rsif.2024.0218

Vira Raichenko, Nikolai Rosenthal, Michaela Eder, Myfanwy E Evans

引用次数: 0

Personalized in silico model for radiation-induced pulmonary fibrosis. 辐射诱发肺纤维化的个性化硅学模型。

IF 3.7 2区综合性期刊

Journal of The Royal Society Interface Pub Date : 2024-11-01 Epub Date: 2024-11-13 DOI: 10.1098/rsif.2024.0525

Eleftherios Ioannou, Myrianthi Hadjicharalambous, Anastasia Malai, Elisavet Papageorgiou, Antri Peraticou, Nicos Katodritis, Dimitrios Vomvas, Vasileios Vavourakis

{"title":"Personalized in silico model for radiation-induced pulmonary fibrosis.","authors":"Eleftherios Ioannou, Myrianthi Hadjicharalambous, Anastasia Malai, Elisavet Papageorgiou, Antri Peraticou, Nicos Katodritis, Dimitrios Vomvas, Vasileios Vavourakis","doi":"10.1098/rsif.2024.0525","DOIUrl":"10.1098/rsif.2024.0525","url":null,"abstract":"Radiation-induced pulmonary fibrosis (RIPF) is a severe late-stage complication of radiotherapy (RT) to the chest area, typically used in lung cancer treatment. This condition is characterized by the gradual and irreversible replacement of healthy lung tissue with fibrous scar tissue, leading to decreased lung function, reduced oxygen exchange and critical respiratory deficiencies. Currently, predicting and managing lung fibrosis post-RT remains challenging, with limited preventive and treatment options. Accurate prediction of fibrosis onset and progression is therefore clinically crucial. We present a personalized in silico model for pulmonary fibrosis that encompasses tumour regression, fibrosis development and lung tissue remodelling post-radiation. Our continuum-based model was developed using data from 12 RT-treated lung cancer patients and integrates computed tomography (CT) and dosimetry data to simulate the spatio-temporal evolution of fibrosis. We demonstrate the ability of the in silico model to capture the extent of fibrosis in the entire cohort with a less than 1% deviation from clinical observations, in addition to providing quantitative metrics of spatial similarity. These findings underscore the potential of the model to improve treatment planning and risk assessment, paving the way for more personalized and effective management of RIPF.","PeriodicalId":17488,"journal":{"name":"Journal of The Royal Society Interface","volume":"21 220","pages":"20240525"},"PeriodicalIF":3.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11557242/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142623215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A two-scale numerical study on the mechanobiology of abdominal aortic aneurysms. 腹主动脉瘤力学生物学的双尺度数值研究。

IF 3.7 2区综合性期刊

Journal of The Royal Society Interface Pub Date : 2023-11-01 DOI: 10.1098/rsif.2023.0472

Misael Dalbosco, Michele Terzano, Thiago A Carniel, Eduardo A Fancello, Gerhard A Holzapfel

{"title":"A two-scale numerical study on the mechanobiology of abdominal aortic aneurysms.","authors":"Misael Dalbosco, Michele Terzano, Thiago A Carniel, Eduardo A Fancello, Gerhard A Holzapfel","doi":"10.1098/rsif.2023.0472","DOIUrl":"10.1098/rsif.2023.0472","url":null,"abstract":"Abdominal aortic aneurysms (AAAs) are a serious condition whose pathophysiology is related to phenomena occurring at different length scales. To gain a better understanding of the disease, this work presents a multi-scale computational study that correlates AAA progression with microstructural and mechanical alterations in the tissue. Macro-scale geometries of a healthy aorta and idealized aneurysms with increasing diameter are developed on the basis of existing experimental data and subjected to physiological boundary conditions. Subsequently, microscopic representative volume elements of the abluminal side of each macro-model are employed to analyse the local kinematics at the cellular scale. The results suggest that the formation of the aneurysm disrupts the micromechanics of healthy tissue, which could trigger collagen growth and remodelling by mechanosensing cells. The resulting changes to the macro-mechanics and microstructure of the tissue seem to establish a new homeostatic state at the cellular scale, at least for the diameter range investigated.","PeriodicalId":17488,"journal":{"name":"Journal of The Royal Society Interface","volume":"20 208","pages":"20230472"},"PeriodicalIF":3.7,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618057/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71424677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Red edge excitation shift spectroscopy is highly sensitive to tryptophan composition. 红边激发位移光谱对色氨酸的组成非常敏感。

IF 3.9 2区综合性期刊

Journal of The Royal Society Interface Pub Date : 2023-11-01 Epub Date: 2023-11-08 DOI: 10.1098/rsif.2023.0337

Annmaree K Warrender, Jolyn Pan, Chris Pudney, Vickery L Arcus, William Kelton

引用次数: 0

Cortex-driven cytoplasmic flows in elongated cells: fluid mechanics and application to nuclear transport in Drosophila embryos. 细长细胞中皮层驱动的细胞质流动:流体力学及其在果蝇胚胎核运输中的应用。

IF 3.9 2区综合性期刊

Journal of The Royal Society Interface Pub Date : 2023-11-01 Epub Date: 2023-11-15 DOI: 10.1098/rsif.2023.0428

Pyae Hein Htet, Eric Lauga

{"title":"Cortex-driven cytoplasmic flows in elongated cells: fluid mechanics and application to nuclear transport in Drosophila embryos.","authors":"Pyae Hein Htet, Eric Lauga","doi":"10.1098/rsif.2023.0428","DOIUrl":"10.1098/rsif.2023.0428","url":null,"abstract":"The Drosophila melanogaster embryo, an elongated multi-nucleated cell, is a classical model system for eukaryotic development and morphogenesis. Recent work has shown that bulk cytoplasmic flows, driven by cortical contractions along the walls of the embryo, enable the uniform spreading of nuclei along the anterior-posterior axis necessary for proper embryonic development. Here, we propose two mathematical models to characterize cytoplasmic flows driven by tangential cortical contractions in elongated cells. Assuming Newtonian fluid flow at low Reynolds number in a spheroidal cell, we first compute the flow field exactly, thereby bypassing the need for numerical computations. We then apply our results to recent experiments on nuclear transport in cell cycles 4-6 of Drosophila embryo development. By fitting the cortical contractions in our model to measurements, we reveal that experimental cortical flows enable near-optimal axial spreading of nuclei. A second mathematical approach, applicable to general elongated cell geometries, exploits a long-wavelength approximation to produce an even simpler solution, with errors below [Formula: see text] compared with the full model. An application of this long-wavelength result to transport leads to fully analytical solutions for the nuclear concentration that capture the essential physics of the system, including optimal axial spreading of nuclei.","PeriodicalId":17488,"journal":{"name":"Journal of The Royal Society Interface","volume":"20 208","pages":"20230428"},"PeriodicalIF":3.9,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645513/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"107591602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Elephants and algorithms: a review of the current and future role of AI in elephant monitoring. 大象和算法:回顾人工智能在大象监测中的当前和未来作用。

IF 3.9 2区综合性期刊

Journal of The Royal Society Interface Pub Date : 2023-11-01 Epub Date: 2023-11-15 DOI: 10.1098/rsif.2023.0367

Leandra Brickson, Libby Zhang, Fritz Vollrath, Iain Douglas-Hamilton, Alexander J Titus

引用次数: 0

Rapid flapping and fibre-reinforced membrane wings are key to high-performance bat flight. 快速扑翼和纤维增强膜翼是蝙蝠高性能飞行的关键。

IF 3.9 2区综合性期刊

Journal of The Royal Society Interface Pub Date : 2023-11-01 Epub Date: 2023-11-15 DOI: 10.1098/rsif.2023.0466

Marin Lauber, Gabriel D Weymouth, Georges Limbert

{"title":"Rapid flapping and fibre-reinforced membrane wings are key to high-performance bat flight.","authors":"Marin Lauber, Gabriel D Weymouth, Georges Limbert","doi":"10.1098/rsif.2023.0466","DOIUrl":"10.1098/rsif.2023.0466","url":null,"abstract":"Bats fly using significantly different wing motions from other fliers, stemming from the complex interplay of their membrane wings' motion and structural properties. Biological studies show that many bats fly at Strouhal numbers, the ratio of flapping to flight speed, 50-150% above the range typically associated with optimal locomotion. We use high-resolution fluid-structure interaction simulations of a bat wing to independently study the role of kinematics and material/structural properties in aerodynamic performance and show that peak propulsive and lift efficiencies for a bat-like wing motion require flapping 66% faster than for a symmetric motion, agreeing with the increased flapping frequency observed in zoological studies. In addition, we find that reduced membrane stiffness is associated with improved propulsive efficiency until the membrane flutters, but that incorporating microstructural anisotropy arising from biological fibre reinforcement enables a tenfold reduction of the flutter energy while maintaining high aerodynamic efficiency. Our results indicate that animals with specialized flapping motions may have correspondingly specialized flapping speeds, in contrast to arguments for a universally efficient Strouhal range. Additionally, our study demonstrates the significant role that the microstructural constitutive properties of the membrane wing of a bat can have in its propulsive performance.","PeriodicalId":17488,"journal":{"name":"Journal of The Royal Society Interface","volume":"20 208","pages":"20230466"},"PeriodicalIF":3.9,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645508/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"107591605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evolutionary rescue on genotypic fitness landscapes. 基因型适应度景观的进化拯救。

IF 3.9 2区综合性期刊

Journal of The Royal Society Interface Pub Date : 2023-11-01 Epub Date: 2023-11-15 DOI: 10.1098/rsif.2023.0424

L M Wahl, Paulo R A Campos

引用次数: 0