Jeffrey J Aalberg, Marc D Kimball, Timothy R McIntire, Geoffrey M McCullen
{"title":"Long-term Outcomes of Persistent Postoperative Opioid Use: A Retrospective Cohort Study.","authors":"Jeffrey J Aalberg, Marc D Kimball, Timothy R McIntire, Geoffrey M McCullen","doi":"10.1097/SLA.0000000000005372","DOIUrl":"10.1097/SLA.0000000000005372","url":null,"abstract":"<p><strong>Objective: </strong>To determine the association between PPOU and the long-term risk of OUD and opioid overdose.</p><p><strong>Summary background data: </strong>PPOU is a commonly used outcome in the surgical literature; its incidence and risk factors have been well described. However, its association to long term outcomes, including OUD and opioid overdose, is unknown.</p><p><strong>Methods: </strong>A retrospective cohort study utilizing the Veterans Health Administration corporate data warehouse. Patients undergoing any surgery between January 1, 2008 and December 31, 2018 were included and followed until December 31, 2020. Univariate and multivariate survival analysis were used to determine the association between PPOU and OUD and overdose. Sensitivity analyses were conducted to determine the impact of different definitions of persistent opioid use and the effect of preoperative opioid use.</p><p><strong>Results: </strong>A total of 344,745 patients undergoing surgery were included and followed for a median of 6.18 years (IQR 3.53-9.12). PPOU was associated with an increased hazard of developing both OUD (HR = 1.88, CI: 1.81-1.95, P < 0.001) and overdose (HR = 1.83, CI: 1.72-1.94, P < 0.001). This association remained consistent after adjustment for comorbidities and across all sensitivity analyses.</p><p><strong>Conclusions: </strong>Surgical patients who develop PPOU are at increased risk of both OUD and overdose as compared to surgical patients who do not develop persistent use.</p>","PeriodicalId":7,"journal":{"name":"ACS Applied Polymer Materials","volume":" ","pages":"116-123"},"PeriodicalIF":4.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39951145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ACS Applied Materials & Interfaces Family Early Career Forum 2024","authors":"Xing Yi Ling, ","doi":"10.1021/acsapm.4c0371410.1021/acsapm.4c03714","DOIUrl":"https://doi.org/10.1021/acsapm.4c03714https://doi.org/10.1021/acsapm.4c03714","url":null,"abstract":"","PeriodicalId":7,"journal":{"name":"ACS Applied Polymer Materials","volume":"6 23","pages":"14023–14025 14023–14025"},"PeriodicalIF":4.4,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142842616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuntong Li, Jiayi Wan, Yan Sui, Wentong Chen, Dongsheng Liu, Wei Huang, Xiaodan Li, Wei Wang, Hong Zhong* and Cheng Liu*,
{"title":"Thiophene Functionalized Linear Conjugated Polymer toward High-Performance Photocatalytic H2O2 Production","authors":"Yuntong Li, Jiayi Wan, Yan Sui, Wentong Chen, Dongsheng Liu, Wei Huang, Xiaodan Li, Wei Wang, Hong Zhong* and Cheng Liu*, ","doi":"10.1021/acsapm.4c0319710.1021/acsapm.4c03197","DOIUrl":"https://doi.org/10.1021/acsapm.4c03197https://doi.org/10.1021/acsapm.4c03197","url":null,"abstract":"<p >Metal-free polymeric photocatalysts with tunable building blocks, ample redox-active centers, and exceptional light-harvesting capability have emerged as promising candidates for generating hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) through the oxygen reduction reaction (ORR) and water oxidation reaction (WOR). The slow kinetics of the WOR process coupled with rapid charge recombination nevertheless impedes the efficient generation of H<sub>2</sub>O<sub>2</sub>. Herein, a thiophene functionalized linear conjugated polymer (DEB-Tp-S<sub>2</sub>) was fabricated for effective overall H<sub>2</sub>O<sub>2</sub> photoproduction. DEB-Tp-S<sub>2</sub> exhibits a high initial photocatalytic H<sub>2</sub>O<sub>2</sub> yield rate of 2762 μmol g<sup>–1</sup> h<sup>–1</sup> in the absence of sacrificial additives and possesses outstanding cycling stability. Experimental and density functional theory (DFT) results exhibit that thiophene moieties can reduce the strength of the O–H bond in H<sub>2</sub>O, which promotes the 4e<sup>–</sup> WOR process, thereby suppressing charge recombination and improving proton supply. This work reveals the indispensable role of chemical structure engineering in polymer photocatalysts for optimizing their H<sub>2</sub>O<sub>2</sub> yield and offers fresh insights into the polymer design for achieving efficient H<sub>2</sub>O<sub>2</sub> production.</p>","PeriodicalId":7,"journal":{"name":"ACS Applied Polymer Materials","volume":"6 23","pages":"14885–14894 14885–14894"},"PeriodicalIF":4.4,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142849936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Synergistically Regulating the Conjugation Length and Side Chain on Oligothiophene-Based Fully Nonfused Ring Electron Acceptors for Efficient Organic Solar Cells","authors":"Renshuang Wu, Xianglin Meng, Qian Yang, Wenjun Zhang, Shuaishuai Shen, Lisi Yang, Miao Li, Yu Chen, Yuanyuan Zhou* and Jinsheng Song*, ","doi":"10.1021/acsapm.4c0282610.1021/acsapm.4c02826","DOIUrl":"https://doi.org/10.1021/acsapm.4c02826https://doi.org/10.1021/acsapm.4c02826","url":null,"abstract":"<p >Fully nonfused ring electron acceptors (FNEAs) have become a research hotspot due to their simple skeletons and reduced synthetic complexity. In this work, with the assistance of a noncovalent conformational lock, we synthesized four FNEAs based on an oligothiophene unit via synergistically regulating the conjugation length and side-chain engineering, which could effectively tune the molecular conformations, absorption spectra, energy levels, intermolecular interactions, and miscibility with polymer. The blend film PBDB-T:<b>4TO</b>-<i>in</i> forms clear bicontinuous interpenetrating networks and more clear phase separation feature due to the balance between crystallization and miscibility. Hence, PBDB-T:<b>4TO</b>-<i>in</i> devices achieved the highest PCE of 10.38%, while an enhanced power conversion efficiency of 11.63% was obtained with the polymer donor replaced by JD40. Overall, this work provides an effective route for oligothiophene-based FNEA design through fine-tuning the molecular skeleton.</p>","PeriodicalId":7,"journal":{"name":"ACS Applied Polymer Materials","volume":"6 23","pages":"14668–14675 14668–14675"},"PeriodicalIF":4.4,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142842256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Isabel Arias Ponce, Rahul Sujanani, Joshua D. Moon, Juan Manuel Urueña, Craig J. Hawker* and Rachel A. Segalman*,
{"title":"3D Printing of Functional Hydrogel Devices for Screenings of Membrane Permeability and Selectivity","authors":"Isabel Arias Ponce, Rahul Sujanani, Joshua D. Moon, Juan Manuel Urueña, Craig J. Hawker* and Rachel A. Segalman*, ","doi":"10.1021/acsapm.4c0273210.1021/acsapm.4c02732","DOIUrl":"https://doi.org/10.1021/acsapm.4c02732https://doi.org/10.1021/acsapm.4c02732","url":null,"abstract":"<p >Developing a fundamental understanding of the effects of varying ligand chemistries on mass transport rates is key to designing membranes with solute-specific selectivity. While permeation cells offer a robust method to characterize membrane performance, they are limited to assessing a single membrane chemistry or salt solution per test. As a result, investigating the effects of varying ligand chemistries on membrane performance can be a tedious process, involving both the preparation of multiple samples and numerous, time-consuming permeation tests. This study uses digital light processing (DLP) 3D printing to fabricate a millifluidic flow-based permeation device made from a hydrogel active ester network that can be easily functionalized with ion-selective ligands. Without the need for bonding or assembly steps, ligands can be introduced and tested in the permeation device by simply injecting a small volume of a ligand solution. Various salt concentrations and molecular species can be cycled through a single device by switching the solution feeding into the salt reservoir, thereby reducing the number of samples needed for permeability and selectivity screenings. This research sets the groundwork for formulation development and postprocessing methods to 3D-print functional millifluidic devices capable of assessing solute selectivity in membranes and polymer adsorbents for aqueous separations. In this work, comparable salt permeability trends were observed with both 3D-printed devices and traditional assays. Devices were functionalized with an imidazole ligand to investigate salt permeability and selectivity of monovalent and divalent salts. Measurements showed increasing permeability for monovalent salts (NaCl) relative to divalent salts (MgCl<sub>2</sub>, CuCl<sub>2</sub>) in functionalized membranes, with higher monovalent/divalent selectivity at increasing imidazole grafting densities. The methods and findings described here represent a step toward developing higher-throughput methods with 3D-printed devices for screening the effects of ligand chemistry on mass transport rates in membrane materials.</p>","PeriodicalId":7,"journal":{"name":"ACS Applied Polymer Materials","volume":"6 23","pages":"14629–14637 14629–14637"},"PeriodicalIF":4.4,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142842197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Long Yu, Fan Wu, Jiarong Zhang, Ya’nan Zhao, Yi’na Yang, Tianran Zhao, Chunna Yu, Chang Zhao and Guangjian Xing*,
{"title":"A Self-Healing, Adhesive, and Anti-Freezing PAA/PEDOT:PSS/Nb2CTX Hydrogel for Flexible Pressure Sensors and Photothermal Therapy","authors":"Long Yu, Fan Wu, Jiarong Zhang, Ya’nan Zhao, Yi’na Yang, Tianran Zhao, Chunna Yu, Chang Zhao and Guangjian Xing*, ","doi":"10.1021/acsapm.4c0331410.1021/acsapm.4c03314","DOIUrl":"https://doi.org/10.1021/acsapm.4c03314https://doi.org/10.1021/acsapm.4c03314","url":null,"abstract":"<p >The conductive hydrogels used for fabricating flexible piezoresistive sensors encounter challenges related to diminished sensing performance due to limited mechanical properties. This study presents the development of a PAA/PEDOT:PSS/Nb<sub>2</sub>CT<sub>X</sub> hydrogel through a straightforward polymerization method. The hydrogel features a cross-linked dual network structure abundant in hydrogen bonds, which imparts exceptional mechanical properties, including stable stretchability, good compressibility, strong adhesion, superior self-healing capabilities, and antifreezing characteristics. With a high conductivity of 165.54 S m<sup>–1</sup>, the piezoresistive sensor based on this hydrogel demonstrates remarkable compressive sensing capabilities, including a low detection limit, a high sensitivity of 9.81, a rapid response/recovery time of merely 200 ms, a wide sensing range, and cyclic stability exceeding 2000 cycles. This sensor effectively detects a variety of human physiological activities, ranging from large joint movements to subtle finger bending and swallowing. Notably, the integration of Nb<sub>2</sub>CT<sub>X</sub> nanosheets, which possess photothermal conversion characteristics, allows the hydrogel to heat up quickly in response to near-infrared light, rendering it suitable for photothermal therapy. The combination of enhanced sensing performance and photothermal treatment potential in this sensor indicates promising applications in human health monitoring and adjunct therapy.</p>","PeriodicalId":7,"journal":{"name":"ACS Applied Polymer Materials","volume":"6 23","pages":"14916–14927 14916–14927"},"PeriodicalIF":4.4,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142850324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Compressible CNT Ink-Wrapped Thermoplastic Polyurethane Sponge for Piezoresistive Sensing and Solar Steam Generation","authors":"Bingqiang Yan, Xia Chen, Ruisi Yao, Yinyin Wang, Zhaoxing Lin, Lihong Xu, Zhenzeng Wu*, Xiangfang Peng* and Tingjie Chen*, ","doi":"10.1021/acsapm.4c0248410.1021/acsapm.4c02484","DOIUrl":"https://doi.org/10.1021/acsapm.4c02484https://doi.org/10.1021/acsapm.4c02484","url":null,"abstract":"<p >The rapid development of wearable flexible electronic devices has brought the demand for supporting functional devices and energy storage devices. Filling conductive materials into elastomeric polymer or rubber films have been proven to be suitable sensing materials to fabricate flexible piezoresistive sensors (PRSs), but they are still confronted with low sensitivity and poor stability. Herein, a porous thermoplastic polyurethane (TPU) sponge is constructed by a simple sacrificial sugar-template strategy. An aqueous printable carbon nanotube (CNT) ink is prepared by a physical ball milling process to improve the conductivity of the TPU sponge. After coating a thin CNT ink layer, a highly compressible and conductive p-TPU@CNT sponge with a 3D porous structure is fabricated. It exhibits a large compressibility (up to 80% compression strain), good structural stability (over 6000 cycles), high piezoresistive sensitivity (7.85 kPa<sup>–1</sup>), and fast response time (54 ms), which can be directly used as a flexible PRS device to monitor and collect joint movements and physiological signals and can be assembled into a compressible supercapacitor with stable electrochemical performance. Furthermore, the hydrophilic p-TPU@CNT sponge with good mechanical and photothermal conversion properties can also be used for solar steam generation with a high efficiency of 92% under 1 sun irradiation.</p>","PeriodicalId":7,"journal":{"name":"ACS Applied Polymer Materials","volume":"6 23","pages":"14436–14446 14436–14446"},"PeriodicalIF":4.4,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142842347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Confinement-Assisted Specific Fluorescence Detection of Fe3+ in Aqueous Solution by Styrylpyrene-Based Microgels","authors":"Wei Huang, Ruijie Hou, Zehui Jiao, Jiefeng Zhu, Xianjing Zhou* and Xinping Wang*, ","doi":"10.1021/acsapm.4c0304410.1021/acsapm.4c03044","DOIUrl":"https://doi.org/10.1021/acsapm.4c03044https://doi.org/10.1021/acsapm.4c03044","url":null,"abstract":"<p >In recent years, fluorescent sensors have played a compelling role in the precise detection of metal ions. However, most fluorophores are hydrophobic and cannot be used to detect aqueous samples directly. Researchers have thus addressed this problem by combining fluorophores with hydrophilic polymer carriers. Nevertheless, most studies have focused only on the role of fluorophores in the recognition of metal ions, ignoring the effect of polymers and their aggregation states on the detection. In this work, microgels with pyrene-based fluorescent cross-linked structures were prepared using a post-cross-linking strategy and were found to specifically detect Fe<sup>3+</sup> directly in aqueous solutions without interference from other metal ions (i.e., Al<sup>3+</sup>, Ba<sup>2+</sup>, Cd<sup>2+</sup>, Co<sup>2+</sup>, Cr<sup>3+</sup>, Cu<sup>2+</sup>, Ni<sup>2+</sup>, Pb<sup>2+</sup>, Zn<sup>2+</sup>, Fe<sup>2+</sup>, Hg<sup>2+</sup>, Na<sup>+</sup>, K<sup>+</sup>, Ca<sup>2+</sup>, or Mg<sup>2+</sup>). The detection limit is 2.3 μM, which is lower than the U.S. Environmental Protection Agency’s safety limit for drinking water. The fluorescence quenching of microgels by Fe<sup>3+</sup> was effective by both mechanisms (dynamic and static), mainly the static one. Nanoscale microgels allow Fe<sup>3+</sup> to be confined around the pyrene of their fluorescent cross-linked structures, which induces nonradiative energy transfer and leads to fluorescence quenching of the microgels. Such a detection method utilizing the confinement effect of microgels to synergize fluorescence quenching provides an idea for the development of fluorescent sensors.</p>","PeriodicalId":7,"journal":{"name":"ACS Applied Polymer Materials","volume":"6 23","pages":"14843–14852 14843–14852"},"PeriodicalIF":4.4,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142850328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Qiang Ding, Tian Chen, Chaoxi Wu* and Shunqing Tang*,
{"title":"Immunomodulatory Nanofibrous Membrane Based on Collagen/Curdlan Acetate for Accelerated Wound Repair","authors":"Qiang Ding, Tian Chen, Chaoxi Wu* and Shunqing Tang*, ","doi":"10.1021/acsapm.4c0296810.1021/acsapm.4c02968","DOIUrl":"https://doi.org/10.1021/acsapm.4c02968https://doi.org/10.1021/acsapm.4c02968","url":null,"abstract":"<p >Collagen is a key component in the extracellular matrix (ECM) with potent immunoregulatory and wound-healing functions. However, its limited processability and stability have hindered its application as a wound dressing. To this end, a composite nanofibrous membrane based on Curdlan acetate (CDA) and bovine type I collagen was developed to broaden the utility of collagen in wound repair. The CDA/collagen nanofibrous membrane (CDAColNM5) demonstrated an average fiber diameter of ∼100 nm, a tensile strength of ∼3.4 MPa, and a swelling degree of ∼540%. The composite membrane also supported the adhesion and proliferation of 3T3 fibroblast cells while upregulating the expression of pro-regenerative cytokines such as IL-6, IL-10, and TGF-β in macrophage models. The immunomodulatory and wound-healing activities of CDAColNM5 were also verified in an animal study. Therefore, these findings suggest that CDAColNM5 represents a promising option for wound management.</p>","PeriodicalId":7,"journal":{"name":"ACS Applied Polymer Materials","volume":"6 23","pages":"14784–14793 14784–14793"},"PeriodicalIF":4.4,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142850327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrew J. Ruba, Prashant Sharan, Michael P. Dugas, Harshul V. Thakkar, Kathryn A. Berchtold and Rajinder P. Singh*,
{"title":"Experimental and Techno-Economic Analysis of Polybenzimidazole Thin-Film Membranes for Efficient Pervaporation Desalination of Produced Water","authors":"Andrew J. Ruba, Prashant Sharan, Michael P. Dugas, Harshul V. Thakkar, Kathryn A. Berchtold and Rajinder P. Singh*, ","doi":"10.1021/acsapm.4c0244110.1021/acsapm.4c02441","DOIUrl":"https://doi.org/10.1021/acsapm.4c02441https://doi.org/10.1021/acsapm.4c02441","url":null,"abstract":"<p >Produced water is a massive wastewater source generated by hydraulic fracturing during oil and gas extraction. Due to high salinity (3000 to >300,000 mg/L) and presence of organic (≤1000 mg/L) impurities, thermal- or membrane-based separation processes of produced water are very expensive and challenging. Elevated temperature membrane desalination processes can efficiently treat high-salinity produced water containing organic impurities, provided thermo-chemical robust membrane materials are developed. Here, a highly selective and dense polybenzimidazole (<i>m</i>-PBI) thin-film membrane was extensively evaluated with a simulated brine, representative of brine produced from the San Juan basin, and a real brine obtained from the Permian Basin to demonstrate its thermo-chemical robustness for the treatment of high-salinity produced water. The membrane showed extremely high stability in the brine solutions at elevated temperatures approaching 200 °C and 99.9% salt and organic rejection, producing high-purity distillate. A detailed techno-economic analysis was carried out for a multistage PBI membrane-based pervaporation process using experimentally obtained data scaled to industrial membrane thicknesses. A minimum cost of $3.49 m<sup>–3</sup> was calculated for an 18-stage pervaporation system to treat produced water, which is 50% lower than that compared to commercial brine concentrator technology for produced water treatment. More efficient elevated temperature pervaporation desalination is achieved by higher operating temperatures enabled by the thermo-chemical durability of the PBI membranes providing opportunities for efficient heat recovery.</p>","PeriodicalId":7,"journal":{"name":"ACS Applied Polymer Materials","volume":"6 23","pages":"14421–14435 14421–14435"},"PeriodicalIF":4.4,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142842237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}