ACS Materials Letters最新文献

Hydrogel System with Independent Tailoring of Mechanics, CT, and US Contrasts for Affordable Medical Phantoms 水凝胶系统可独立调整力学、CT 和 US 对比度，实现经济实惠的医学模型

IF 9.6 1区化学

ACS Materials Letters Pub Date : 2024-09-26 DOI: 10.1021/acsmaterialslett.4c0166010.1021/acsmaterialslett.4c01660

Haoyi Qiu, Jakob Nazarenus, Bernhard Egeler, Tom Thode, Firdaws Osman, Daniar Osmonov, Jörg Bahr, Sören Kaps, Frank-Andre Siebert, Reinhard Koch, Ulf Lützen, Rainer Adelung* and Leonard Siebert*,

{"title":"Hydrogel System with Independent Tailoring of Mechanics, CT, and US Contrasts for Affordable Medical Phantoms","authors":"Haoyi Qiu, Jakob Nazarenus, Bernhard Egeler, Tom Thode, Firdaws Osman, Daniar Osmonov, Jörg Bahr, Sören Kaps, Frank-Andre Siebert, Reinhard Koch, Ulf Lützen, Rainer Adelung* and Leonard Siebert*, ","doi":"10.1021/acsmaterialslett.4c0166010.1021/acsmaterialslett.4c01660","DOIUrl":"https://doi.org/10.1021/acsmaterialslett.4c01660https://doi.org/10.1021/acsmaterialslett.4c01660","url":null,"abstract":"Medical phantoms mimic aspects of procedures like computed tomography (CT), ultrasound (US) imaging, and surgical practices. However, the materials for current commercial phantoms are expensive and the fabrication with these is complex and lacks versatility. Therefore, existing material solutions are not suitable for creating patient-specific phantoms. We present a novel and cost-effective material system (utilizing ubiquitous sodium alginate hydrogel and coconut fat) with independently and accurately tailorable CT, US, and mechanical properties. By varying the concentration of alginate, cross-linker, and coconut fat, the radiological parameters and the elastic modulus were adjusted independently in a wide range. The independence was demonstrated by creating phantoms with features hidden in US, while visible in CT imaging and vice versa. This system is particularly beneficial in resource-scarce areas since the materials are cheap (<$ 1 USD/kg) and easy to obtain, offering realistic and versatile phantoms to practice surgeries and ultimately enhance patient care.","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":null,"pages":null},"PeriodicalIF":9.6,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsmaterialslett.4c01660","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142408514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Charge-Conversion-Induced Complexation Toughening of Adaptive and Degradable Protein Optical Fibers for Interventional Cancer Therapy 电荷转换诱导络合增韧自适应可降解蛋白质光纤，用于癌症介入治疗

IF 9.6 1区化学

ACS Materials Letters Pub Date : 2024-09-26 DOI: 10.1021/acsmaterialslett.4c0141410.1021/acsmaterialslett.4c01414

Zhe Lu, Hanyue Xue, Xiang He, Bowen Qiao, Kan Li, Ping Zhang, Hongqiu Wei, Lingyan Gao, Jianjian Zhang, Baolin Guo and You Yu*,

{"title":"Charge-Conversion-Induced Complexation Toughening of Adaptive and Degradable Protein Optical Fibers for Interventional Cancer Therapy","authors":"Zhe Lu, Hanyue Xue, Xiang He, Bowen Qiao, Kan Li, Ping Zhang, Hongqiu Wei, Lingyan Gao, Jianjian Zhang, Baolin Guo and You Yu*, ","doi":"10.1021/acsmaterialslett.4c0141410.1021/acsmaterialslett.4c01414","DOIUrl":"https://doi.org/10.1021/acsmaterialslett.4c01414https://doi.org/10.1021/acsmaterialslett.4c01414","url":null,"abstract":"Protein hydrogel fibers hold great promise for diverse applications. However, the challenge lies in developing rapid and straightforward methods for the one-step fabrication of high-performance protein-based hydrogel optical fibers. Here, we present a general charge-conversion-induced complexation toughening (CCICT) strategy for preparing protein hydrogel fibers in 15 s. The in situ introduction of polyelectrolyte–micelle complexes enhances the fibers’ mechanical, antiswelling, and antibacterial properties. The protein components confer biocompatibility, enzymatic degradability, and strong tissue adhesion to the hydrogel fibers. Furthermore, the as-prepared fibers demonstrate excellent optical transmission with minimal attenuation of 0.15–0.50 dB cm–1 across various wavelengths. The hierarchical multinetwork structure imparts outstanding adaptability and stability in mechanical and optical performance. Also, the protein fibers effectively deliver light for interventional photothermal cancer therapy beneath the skin of mice. Their rapid degradation in physiological environments promotes efficient wound healing. Therefore, this developed CCICT approach and these high-performance protein fibers are anticipated to have broad applications.","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":null,"pages":null},"PeriodicalIF":9.6,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142408180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Viologen Unlocks Photogenerated Carrier Confinement in Low-Dimensional Perovskites for High-Stability and High-Gain X-ray Detection Viologen 开启低维包晶石中的光生载流子禁锢，实现高稳定性和高增益 X 射线探测

IF 9.6 1区化学

ACS Materials Letters Pub Date : 2024-09-26 DOI: 10.1021/acsmaterialslett.4c0175310.1021/acsmaterialslett.4c01753

De Lin Hu, Jing Yuan Guo, Mei-Juan Xie, Ming-Sheng Wang*, Fa-Kun Zheng and Guo-Cong Guo*,

{"title":"Viologen Unlocks Photogenerated Carrier Confinement in Low-Dimensional Perovskites for High-Stability and High-Gain X-ray Detection","authors":"De Lin Hu, Jing Yuan Guo, Mei-Juan Xie, Ming-Sheng Wang*, Fa-Kun Zheng and Guo-Cong Guo*, ","doi":"10.1021/acsmaterialslett.4c0175310.1021/acsmaterialslett.4c01753","DOIUrl":"https://doi.org/10.1021/acsmaterialslett.4c01753https://doi.org/10.1021/acsmaterialslett.4c01753","url":null,"abstract":"The simultaneous attainment of high-photoelectric performance and stability has long been a challenge for hybrid perovskites, which are typically characterized by the low stability of three-dimensional perovskites and the poor photoelectric performance of low-dimensional perovskites. Here, we present a novel perovskite assembly strategy aimed at enhancing both the photoelectric gain and stability for X-ray detection. This strategy employs a viologen as a cation, leveraging its strong electrostatic interaction, low LUMO, and capability for photogenerated charge separation and transport to enhance stability, reduce the band gap, and unlock photogenerated carrier barriers while integrating the benefits of low-dimensional perovskites. The obtained zero-dimensional viologen perovskite exhibits exceptional comprehensive performance, including high X-ray detection performance (in vacuum), low X-ray dose rate resolution, inhibited ion migration, low dark current drift and noise current, and remarkable chemical and long-term stability (sustained in air with 50–75% relative humidity for 1 year, followed by 60 h of UV irradiation at 80 °C).","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":null,"pages":null},"PeriodicalIF":9.6,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsmaterialslett.4c01753","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142408186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hydrogel System with Independent Tailoring of Mechanics, CT, and US Contrasts for Affordable Medical Phantoms. 水凝胶系统可独立调整力学、CT 和 US 对比度，实现经济实惠的医学模型。

IF 9.6 1区化学

ACS Materials Letters Pub Date : 2024-09-26 eCollection Date: 2024-10-07 DOI: 10.1021/acsmaterialslett.4c01660

Haoyi Qiu, Jakob Nazarenus, Bernhard Egeler, Tom Thode, Firdaws Osman, Daniar Osmonov, Jörg Bahr, Sören Kaps, Frank-Andre Siebert, Reinhard Koch, Ulf Lützen, Rainer Adelung, Leonard Siebert

{"title":"Hydrogel System with Independent Tailoring of Mechanics, CT, and US Contrasts for Affordable Medical Phantoms.","authors":"Haoyi Qiu, Jakob Nazarenus, Bernhard Egeler, Tom Thode, Firdaws Osman, Daniar Osmonov, Jörg Bahr, Sören Kaps, Frank-Andre Siebert, Reinhard Koch, Ulf Lützen, Rainer Adelung, Leonard Siebert","doi":"10.1021/acsmaterialslett.4c01660","DOIUrl":"10.1021/acsmaterialslett.4c01660","url":null,"abstract":"Medical phantoms mimic aspects of procedures like computed tomography (CT), ultrasound (US) imaging, and surgical practices. However, the materials for current commercial phantoms are expensive and the fabrication with these is complex and lacks versatility. Therefore, existing material solutions are not suitable for creating patient-specific phantoms. We present a novel and cost-effective material system (utilizing ubiquitous sodium alginate hydrogel and coconut fat) with independently and accurately tailorable CT, US, and mechanical properties. By varying the concentration of alginate, cross-linker, and coconut fat, the radiological parameters and the elastic modulus were adjusted independently in a wide range. The independence was demonstrated by creating phantoms with features hidden in US, while visible in CT imaging and vice versa. This system is particularly beneficial in resource-scarce areas since the materials are cheap (<$ 1 USD/kg) and easy to obtain, offering realistic and versatile phantoms to practice surgeries and ultimately enhance patient care.","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":null,"pages":null},"PeriodicalIF":9.6,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11463687/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142398651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Precisely Designed Calcium-Based Nanomaterials: From Regulation of Cellular Ca2+ Homeostasis to Cancer Therapy 精确设计的钙基纳米材料：从调节细胞 Ca2+ 平衡到癌症治疗

IF 9.6 1区化学

ACS Materials Letters Pub Date : 2024-09-25 DOI: 10.1021/acsmaterialslett.4c0143210.1021/acsmaterialslett.4c01432

Lin-Fei Chen, Ying-Tong Ye, Ruo-Yin Meng, Hong-Ying Xia, Biao-Qi Chen, Shi-Bin Wang, Ranjith Kumar Kankala* and Ai-Zheng Chen*,

{"title":"Precisely Designed Calcium-Based Nanomaterials: From Regulation of Cellular Ca2+ Homeostasis to Cancer Therapy","authors":"Lin-Fei Chen, Ying-Tong Ye, Ruo-Yin Meng, Hong-Ying Xia, Biao-Qi Chen, Shi-Bin Wang, Ranjith Kumar Kankala* and Ai-Zheng Chen*, ","doi":"10.1021/acsmaterialslett.4c0143210.1021/acsmaterialslett.4c01432","DOIUrl":"https://doi.org/10.1021/acsmaterialslett.4c01432https://doi.org/10.1021/acsmaterialslett.4c01432","url":null,"abstract":"Intracellular calcium ion (Ca2+) homeostasis is closely associated with the maintenance of cellular functions and even influences the process of cellular fate. Particularly, Ca2+ homeostasis directly or indirectly participates in various methods of tumor occurrence and development, including proliferation, migration, and apoptosis of tumor cells. Considering the advancements in strategies for cancer therapy based on disrupting Ca2+ homeostasis, this article provides a comprehensive review from the perspective of the relationship between Ca2+ homeostasis and tumor therapy, focusing on the common Ca2+-based nanomaterials and self-regulatory mechanisms of Ca2+ homeostasis toward diagnostic and therapeutic applications. Notably, the disruption of Ca2+ homeostasis provides exceptional possibilities for the design of Ca2+-based nanomaterials through various pathways, such as inducing Ca2+ overload to directly kill tumor cells, indirectly inhibiting tumor growth by affecting various tumor microenvironments, and promoting calcification phenomena for bioimaging in tumor diagnosis. Finally, we summarize the article with a perspective, exploring limitations and challenges in applying Ca2+-based materials mediated by disrupting Ca2+ homeostasis and providing prospects for their clinical development.","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":null,"pages":null},"PeriodicalIF":9.6,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142403504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High-Flux Hard X-ray Cs1–mRbmPbBr3 Single-Crystal Detector with Suppressed Ion Migration 抑制离子迁移的高通量硬 X 射线 Cs1-mRbmPbBr3 单晶探测器

IF 9.6 1区化学

ACS Materials Letters Pub Date : 2024-09-25 DOI: 10.1021/acsmaterialslett.4c0155910.1021/acsmaterialslett.4c01559

Peng Zhang*, Lin Huang, Lili Li, Zhaolai Chen, Guodong Zhang and Xutang Tao*,

{"title":"High-Flux Hard X-ray Cs1–mRbmPbBr3 Single-Crystal Detector with Suppressed Ion Migration","authors":"Peng Zhang*, Lin Huang, Lili Li, Zhaolai Chen, Guodong Zhang and Xutang Tao*, ","doi":"10.1021/acsmaterialslett.4c0155910.1021/acsmaterialslett.4c01559","DOIUrl":"https://doi.org/10.1021/acsmaterialslett.4c01559https://doi.org/10.1021/acsmaterialslett.4c01559","url":null,"abstract":"All-inorganic perovskite CsPbBr3 single crystals are considered a next-generation X-ray detector owing to their excellent photoelectric properties. However, strong ion migration hinders the application of CsPbBr3 detectors, especially those irradiated under high-flux hard X-rays. Herein, we prepared Cs1–mRbmPbBr3 single crystals by partially replacing Cs atoms with Rb atoms to intensify the lattice distortion and suppress ion migration in CsPbBr3. A Cs0.7Rb0.3PbBr3 single-crystal detector operating at 120 kVp X-rays with a flux of up to 106 photons s–1 mm–2 was produced. This Cs0.7Rb0.3PbBr3 detector shows a dark current density as low as 1.01 μA cm–2, a high sensitivity of 33631 μC Gy1– cm–2, and a low detection limit of 148 nGy s–1 under 120 kVp X-rays. Furthermore, the Cs0.7Rb0.3PbBr3 detector exhibits a stable X-ray detection capability for over 30 days under ambient conditions, indicating its potential for wide-scale application in high-flux hard X-ray detection.","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":null,"pages":null},"PeriodicalIF":9.6,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142403977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chemisorption Manipulation by Adjusting the Carrier Concentration of the Adsorbent and Its Application to Adsorbate Identification 通过调整吸附剂载体浓度进行化学吸附操作及其在吸附剂鉴定中的应用

IF 9.6 1区化学

ACS Materials Letters Pub Date : 2024-09-24 DOI: 10.1021/acsmaterialslett.4c0172910.1021/acsmaterialslett.4c01729

Gyuweon Jung, Kangwook Choi, Suyeon Ju, Jaehyeon Kim, Wonjun Shin, Seongi Lee, Gyuho Yeom, Ryun-Han Koo, Young-Chang Joo, Woo Young Choi, Seungwu Han and Jong-Ho Lee*,

{"title":"Chemisorption Manipulation by Adjusting the Carrier Concentration of the Adsorbent and Its Application to Adsorbate Identification","authors":"Gyuweon Jung, Kangwook Choi, Suyeon Ju, Jaehyeon Kim, Wonjun Shin, Seongi Lee, Gyuho Yeom, Ryun-Han Koo, Young-Chang Joo, Woo Young Choi, Seungwu Han and Jong-Ho Lee*, ","doi":"10.1021/acsmaterialslett.4c0172910.1021/acsmaterialslett.4c01729","DOIUrl":"https://doi.org/10.1021/acsmaterialslett.4c01729https://doi.org/10.1021/acsmaterialslett.4c01729","url":null,"abstract":"Progress in techniques for manipulating chemisorption has substantially advanced various applications. Herein, we present a widely applicable method to manipulate chemisorption by adjusting the carrier concentration of the adsorbent. We demonstrate that in both n- and p-type adsorbents, an increase in the electron concentration of the adsorbent enhances the chemisorption of oxidizing adsorbates. In contrast, a decrease in electron concentration promotes the chemisorption of reducing adsorbates. These findings are verified using first-principles calculations based on density functional theory. We demonstrate that the adsorption energy of the adsorbate and the energy difference between the adsorbate states and the Fermi energy can be manipulated by the proposed method. The manipulation method yields different effects for each adsorbate. Therefore, the degree of manipulation can be utilized as a unique fingerprint for adsorbate identification. The proposed method allows for repeatable manipulations and is compatible with existing techniques.","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":null,"pages":null},"PeriodicalIF":9.6,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142403622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Low-Coordinated Pd–Pb Sites in Porous Pd3Pb Metallene Aerogels Promote Polyalcohol Electrochemical Oxidation 多孔 Pd3Pb 茂金属气凝胶中的低配位 Pd-Pb 位点可促进多元醇电化学氧化

IF 9.6 1区化学

ACS Materials Letters Pub Date : 2024-09-24 DOI: 10.1021/acsmaterialslett.4c0157310.1021/acsmaterialslett.4c01573

Hui Fu, Zhen Huang, Ting Zhu*, Liheng Guan, Chih-Wen Pao, Wei-Hsiang Huang*, Nan Zhang* and Tianxi Liu*,

{"title":"Low-Coordinated Pd–Pb Sites in Porous Pd3Pb Metallene Aerogels Promote Polyalcohol Electrochemical Oxidation","authors":"Hui Fu, Zhen Huang, Ting Zhu*, Liheng Guan, Chih-Wen Pao, Wei-Hsiang Huang*, Nan Zhang* and Tianxi Liu*, ","doi":"10.1021/acsmaterialslett.4c0157310.1021/acsmaterialslett.4c01573","DOIUrl":"https://doi.org/10.1021/acsmaterialslett.4c01573https://doi.org/10.1021/acsmaterialslett.4c01573","url":null,"abstract":"Low-coordinated sites can effectively activate adsorbants and promote electrochemical reactions with slow kinetics and multielectron transfer processes, but achieving high exposure rates of low-coordinated sites on the electrocatalyst surface remains challenging. Herein, we first present the synthesis of the porous Pd3Pb metallene aerogels (MAs) with low-coordinated Pd–Pb sites through dynamic reconfiguration strategy for alcohol oxidation reaction (AOR). The porous Pd3Pb MAs possess high mass activity (1.63 A mgPd–1), specific activity (6.28 mA cm–2), and antipoisoning property in ethylene glycol oxidation reaction (EGOR), superior to other prepared catalysts. The same trend was observed in the ethanol oxidation reaction and glycerol oxidation reaction. Mechanism studies show that porous Pd3Pb MAs with low-coordinated Pd–Pb sites could provide more unsaturated sites for adsorption and activation of ethylene glycol, as well as lowering the reaction energy barriers of CH2OHCHO*, CH2OHCOO*, and COOCOO*. This work explored a novel idea for the design Pd-based catalysts in antipoisoned AOR.","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":null,"pages":null},"PeriodicalIF":9.6,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142403668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Au Nanorods Activate Zn2+/Ag+ Mediated Anti-inflammatory for Enhanced Methicillin-Resistant Wound Repair via Bionic Claw Microneedles 金纳米棒激活 Zn2+/Ag+ 介导的抗炎作用，通过仿生爪微针增强耐甲氧西林伤口修复能力

IF 9.6 1区化学

ACS Materials Letters Pub Date : 2024-09-24 DOI: 10.1021/acsmaterialslett.4c0154610.1021/acsmaterialslett.4c01546

Wang Zheng, Hui Shen, Yuanfang Cheng, Litao Liu, Jiangwei Sun, Zhaoyou Chu*, Wanni Wang* and Haisheng Qian*,

{"title":"Au Nanorods Activate Zn2+/Ag+ Mediated Anti-inflammatory for Enhanced Methicillin-Resistant Wound Repair via Bionic Claw Microneedles","authors":"Wang Zheng, Hui Shen, Yuanfang Cheng, Litao Liu, Jiangwei Sun, Zhaoyou Chu*, Wanni Wang* and Haisheng Qian*, ","doi":"10.1021/acsmaterialslett.4c0154610.1021/acsmaterialslett.4c01546","DOIUrl":"https://doi.org/10.1021/acsmaterialslett.4c01546https://doi.org/10.1021/acsmaterialslett.4c01546","url":null,"abstract":"Wound infections caused by methicillin-resistant Staphylococcus aureus (MRSA) have attracted wide attention owing to acidic biofilms and the alkaline wound microenvironment, which result in hindering wound healing. In this work, we prepared an acid–base responsive bionic claw microneedle (MN) loaded with Au@ZnO/Ag (AZA) core–shell nanoparticles, which shows excellent photothermal transition and antibacterial activity. In the acidic medium of the biofilm, 97.98% of bacteria were successfully eradicated under mild thermal conditions (≤40 °C). In the alkaline wound microenvironment, inflammatory cytokines were inhibited by Ag+. Vascular endothelial growth factor expression was promoted by trace Zn2+, and the wound healing rate increased by up to 24.02% compared to the control group. The bionic claw MN loaded with AZA effectively combines the benefits of low-temperature acidic sterilization and alkaline anti-inflammatory activity. The promotion of MRSA infected wound healing through the synergistic effect of released Zn2+/Ag+ and the mild thermal impact showcases new avenues for clinical treatment.","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":null,"pages":null},"PeriodicalIF":9.6,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142403667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pore-Refined Biobased Aerogel for Gas-Sensitive Intelligent Colorimetric Tags 用于气敏智能比色标签的细孔生物气凝胶

IF 9.6 1区化学

ACS Materials Letters Pub Date : 2024-09-23 DOI: 10.1021/acsmaterialslett.4c0186810.1021/acsmaterialslett.4c01868

Xiaosen Pan, Wanlong Song, Huanyu Qian, Guohua Zhang, Ruiming Liu, Xiaojuan Wang*, Fengbao Chen*, Meng Gao* and Zhengjian Zhang,

{"title":"Pore-Refined Biobased Aerogel for Gas-Sensitive Intelligent Colorimetric Tags","authors":"Xiaosen Pan, Wanlong Song, Huanyu Qian, Guohua Zhang, Ruiming Liu, Xiaojuan Wang*, Fengbao Chen*, Meng Gao* and Zhengjian Zhang, ","doi":"10.1021/acsmaterialslett.4c0186810.1021/acsmaterialslett.4c01868","DOIUrl":"https://doi.org/10.1021/acsmaterialslett.4c01868https://doi.org/10.1021/acsmaterialslett.4c01868","url":null,"abstract":"Biobased materials with superior porosity are the preferred choice for high-performance and environmentally friendly gas sensors. Here, a pore-refined colorimetric aerogel with significant-improved porous structure and mechanical integrity is developed through the strategic incorporation of hydrophilic poly(vinyl alcohol) (PVA) in nanocellulose, evidenced by a 14.35-fold increase in surface area, a 21.24-fold improvement in pore volume, and a 16.91-fold rise in gas adsorption–desorption capacity, along with advancements in both static (5.20-fold) and dynamic (5.59-fold) compressive strengths. The enhancement in performance is attributed to the addition of PVA, which promotes uniformity in the gel network and forms hydrogen bonds with cellulose, thereby minimizing structural changes during drying and refining of the pore structure. The aerogels demonstrate sensitive, gradient, recognizable, and highly reversible color changes to ammonia stimuli (down to 10 ppm). Intelligent tags based on the enhanced aerogels demonstrate earlier identification of spoilage in monitoring different types of meat, proving their potential in smart packaging.","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":null,"pages":null},"PeriodicalIF":9.6,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142408135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0