ACS Materials Letters最新文献_第10页

Genetically Encoded Incorporation of IFN-α into Collagen-like Protein–Hyaluronic Acid Hydrogels for Diabetic Chronic Wound Healing 通过基因编码将 IFN-α 加入胶原样蛋白-透明质酸水凝胶，促进糖尿病慢性伤口愈合

IF 11.4 1区化学

ACS Materials Letters Pub Date : 2024-08-12 DOI: 10.1021/acsmaterialslett.4c01170

Jie Wang, Jiaqi Li, Yinan Sun, Xing Liu, Liping Wang, Yan Xia, Jinxia Huang, Jian Feng, Shuang Jia, Yimiao Li, Zhao Guo, Yuxin Dong, Liyao Wang, Xinyu Li

{"title":"Genetically Encoded Incorporation of IFN-α into Collagen-like Protein–Hyaluronic Acid Hydrogels for Diabetic Chronic Wound Healing","authors":"Jie Wang, Jiaqi Li, Yinan Sun, Xing Liu, Liping Wang, Yan Xia, Jinxia Huang, Jian Feng, Shuang Jia, Yimiao Li, Zhao Guo, Yuxin Dong, Liyao Wang, Xinyu Li","doi":"10.1021/acsmaterialslett.4c01170","DOIUrl":"https://doi.org/10.1021/acsmaterialslett.4c01170","url":null,"abstract":"The role of interferon-alpha is critical in modulating immune responses and the wound healing process. However, the rapid degradation and short lifespan of IFN-α in the body limit its therapeutic efficacy in wound management. This study presents an innovative approach to enhancing diabetic wound repair through the incorporation of IFN-α into double network hydrogels composed of hyaluronic acid and collagen-like protein (CLP). Two incorporation methods were evaluated: genetic fusion and spy-chemistry ligation. Our results demonstrate that IFN-α incorporated via spy-chemistry significantly outperformed genetic fusion in terms of cell viability, migration, and protein expression. In vivo studies further confirmed that spy-chemistry ligated IFN-α HA-CLP hydrogels markedly improved wound healing, as evidenced by elevated levels of COL-1α, CK-14, and α-SMA, compared to blank HA-CLP hydrogels and saline-treated controls. These findings underscore the potential of spy-chemistry ligated IFN-α-HA-CLP hydrogels as a promising therapeutic strategy for promoting effective wound healing in diabetic patients.","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":null,"pages":null},"PeriodicalIF":11.4,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141935174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetically Encoded Incorporation of IFN-α into Collagen-like Protein–Hyaluronic Acid Hydrogels for Diabetic Chronic Wound Healing 通过基因编码将 IFN-α 加入胶原样蛋白-透明质酸水凝胶，促进糖尿病慢性伤口愈合

IF 9.6 1区化学

ACS Materials Letters Pub Date : 2024-08-12 DOI: 10.1021/acsmaterialslett.4c0117010.1021/acsmaterialslett.4c01170

Jie Wang, Jiaqi Li, Yinan Sun, Xing Liu, Liping Wang, Yan Xia, Jinxia Huang, Jian Feng, Shuang Jia, Yimiao Li, Zhao Guo, Yuxin Dong, Liyao Wang and Xinyu Li*,

{"title":"Genetically Encoded Incorporation of IFN-α into Collagen-like Protein–Hyaluronic Acid Hydrogels for Diabetic Chronic Wound Healing","authors":"Jie Wang, Jiaqi Li, Yinan Sun, Xing Liu, Liping Wang, Yan Xia, Jinxia Huang, Jian Feng, Shuang Jia, Yimiao Li, Zhao Guo, Yuxin Dong, Liyao Wang and Xinyu Li*, ","doi":"10.1021/acsmaterialslett.4c0117010.1021/acsmaterialslett.4c01170","DOIUrl":"https://doi.org/10.1021/acsmaterialslett.4c01170https://doi.org/10.1021/acsmaterialslett.4c01170","url":null,"abstract":"The role of interferon-alpha is critical in modulating immune responses and the wound healing process. However, the rapid degradation and short lifespan of IFN-α in the body limit its therapeutic efficacy in wound management. This study presents an innovative approach to enhancing diabetic wound repair through the incorporation of IFN-α into double network hydrogels composed of hyaluronic acid and collagen-like protein (CLP). Two incorporation methods were evaluated: genetic fusion and spy-chemistry ligation. Our results demonstrate that IFN-α incorporated via spy-chemistry significantly outperformed genetic fusion in terms of cell viability, migration, and protein expression. In vivo studies further confirmed that spy-chemistry ligated IFN-α HA-CLP hydrogels markedly improved wound healing, as evidenced by elevated levels of COL-1α, CK-14, and α-SMA, compared to blank HA-CLP hydrogels and saline-treated controls. These findings underscore the potential of spy-chemistry ligated IFN-α-HA-CLP hydrogels as a promising therapeutic strategy for promoting effective wound healing in diabetic patients.","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":null,"pages":null},"PeriodicalIF":9.6,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142117186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multifunctional Ternary Oxide for Efficient CsPbBr3 Perovskite Solar Cells on Rigid and Flexible Substrate via All-Low-Temperature Process 通过全低温工艺在刚性和柔性基底上实现高效碲化镉硼三元包光体太阳能电池的多功能三元氧化物

IF 9.6 1区化学

ACS Materials Letters Pub Date : 2024-08-08 DOI: 10.1021/acsmaterialslett.4c0125510.1021/acsmaterialslett.4c01255

Bo Xiao, Zijun Yi, Yuchen Xiong, Yihuai Huang, Wenguang Zhang, Qinghui Jiang, Abdul Basit, Guibin Shen, Yubo Luo, Xin Li* and Junyou Yang*,

{"title":"Multifunctional Ternary Oxide for Efficient CsPbBr3 Perovskite Solar Cells on Rigid and Flexible Substrate via All-Low-Temperature Process","authors":"Bo Xiao, Zijun Yi, Yuchen Xiong, Yihuai Huang, Wenguang Zhang, Qinghui Jiang, Abdul Basit, Guibin Shen, Yubo Luo, Xin Li* and Junyou Yang*, ","doi":"10.1021/acsmaterialslett.4c0125510.1021/acsmaterialslett.4c01255","DOIUrl":"https://doi.org/10.1021/acsmaterialslett.4c01255https://doi.org/10.1021/acsmaterialslett.4c01255","url":null,"abstract":"Efficient CsPbBr3 perovskite films and the low-temperature fabrication of electron transport layers (ETLs) are crucial for the commercial viability of CsPbBr3 perovskite solar cells (PSCs). We present a vapor-assisted solution technique that produces high-quality CsPbBr3 perovskite films without annealing. Doping ZnO with trivalent metals such as yttrium (Y), antimony (Sb), and iron (Fe) improves the electrical properties and energy alignment with CsPbBr3. Our experiments show that Sb doping enhances charge extraction and reduces interface carrier recombination to achieve a power conversion efficiency (PCE) of 9.55% in the inorganic CsPbBr3 PSCs. The optimized device maintains over 90% of its original PCE after 90 days under 65% relative humidity and 65 °C. Additionally, flexible CsPbBr3 PSCs with an Sb-ZnO ETL achieve a record 6.06% efficiency with remarkable mechanical durability to retain 91.8% of initial PCE after 1000 bending cycles at a 3 mm curvature radius.","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":null,"pages":null},"PeriodicalIF":9.6,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142117319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multifunctional Ternary Oxide for Efficient CsPbBr3 Perovskite Solar Cells on Rigid and Flexible Substrate via All-Low-Temperature Process 通过全低温工艺在刚性和柔性基底上实现高效碲化镉硼三元包光体太阳能电池的多功能三元氧化物

IF 9.6 1区化学

ACS Materials Letters Pub Date : 2024-08-08 DOI: 10.1021/acsmaterialslett.4c01255

B. Xiao, Zijun Yi, Yuchen Xiong, Yihuai Huang, Wenguang Zhang, Q. Jiang, Abdul Basit, Guibin Shen, Yubo Luo, Xin Li, Junyou Yang

引用次数: 0

Strongly-Confined CsPbI3 Quantum Dots by Surface Cleaning-Induced Ligand Exchange for Spectrally Stable Pure-Red Light-Emitting Diodes with Efficiency Exceeding 26% 通过表面清洁诱导配体交换实现强致密 CsPbI3 量子点，从而生产出光谱稳定、效率超过 26% 的纯红光发光二极管

IF 9.6 1区化学

ACS Materials Letters Pub Date : 2024-08-07 DOI: 10.1021/acsmaterialslett.4c0091210.1021/acsmaterialslett.4c00912

Ke Ren, Jingcong Hu, Chenghao Bi*, Shibo Wei, Xingyu Wang, Nora H. de Leeuw, Yue Lu*, Manling Sui* and Wenxin Wang*,

{"title":"Strongly-Confined CsPbI3 Quantum Dots by Surface Cleaning-Induced Ligand Exchange for Spectrally Stable Pure-Red Light-Emitting Diodes with Efficiency Exceeding 26%","authors":"Ke Ren, Jingcong Hu, Chenghao Bi*, Shibo Wei, Xingyu Wang, Nora H. de Leeuw, Yue Lu*, Manling Sui* and Wenxin Wang*, ","doi":"10.1021/acsmaterialslett.4c0091210.1021/acsmaterialslett.4c00912","DOIUrl":"https://doi.org/10.1021/acsmaterialslett.4c00912https://doi.org/10.1021/acsmaterialslett.4c00912","url":null,"abstract":"The advancement of pure-red perovskite light-emitting diodes (PeLEDs) is still a challenge because of surface “wastes” (like surface vacancies and excessive insulating ligands) on quantum dots (QDs). Herein, we develop a method to synthesize single-halide pure-red CsPbI3 QDs, combining a strong quantum confinement effect and meticulous surface-cleaning-induced ligand exchange. We achieve pure-red emitting QDs by controlling the size and uniformity under iodide-rich conditions. Subsequently, vacancy defects and insulating ligands are cleared through introducing acid. Then this surface-cleaning process induces ligand exchange to further inhibit the nonradiative recombination and improve the electrical property of QDs. These QDs show a pure-red photoluminescence (PL) at 635 nm with the PL quantum yield (PLQY) of 99%. Finally, PeLEDs, which utilize these QDs, demonstrate a pure-red electroluminescence (EL) peak at 638 nm with a maximum external quantum efficiency (EQE) of 26.0% and an excellent half-lifetime (T50) of 490 min at an original luminance of 102 cd/m2.","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":null,"pages":null},"PeriodicalIF":9.6,"publicationDate":"2024-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142117252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Strongly-Confined CsPbI3 Quantum Dots by Surface Cleaning-Induced Ligand Exchange for Spectrally Stable Pure-Red Light-Emitting Diodes with Efficiency Exceeding 26% 通过表面清洁诱导配体交换实现强致密 CsPbI3 量子点，从而生产出光谱稳定、效率超过 26% 的纯红光发光二极管

IF 11.4 1区化学

ACS Materials Letters Pub Date : 2024-08-07 DOI: 10.1021/acsmaterialslett.4c00912

Ke Ren, Jingcong Hu, Chenghao Bi, Shibo Wei, Xingyu Wang, Nora H. de Leeuw, Yue Lu, Manling Sui, Wenxin Wang

{"title":"Strongly-Confined CsPbI3 Quantum Dots by Surface Cleaning-Induced Ligand Exchange for Spectrally Stable Pure-Red Light-Emitting Diodes with Efficiency Exceeding 26%","authors":"Ke Ren, Jingcong Hu, Chenghao Bi, Shibo Wei, Xingyu Wang, Nora H. de Leeuw, Yue Lu, Manling Sui, Wenxin Wang","doi":"10.1021/acsmaterialslett.4c00912","DOIUrl":"https://doi.org/10.1021/acsmaterialslett.4c00912","url":null,"abstract":"The advancement of pure-red perovskite light-emitting diodes (PeLEDs) is still a challenge because of surface “wastes” (like surface vacancies and excessive insulating ligands) on quantum dots (QDs). Herein, we develop a method to synthesize single-halide pure-red CsPbI3 QDs, combining a strong quantum confinement effect and meticulous surface-cleaning-induced ligand exchange. We achieve pure-red emitting QDs by controlling the size and uniformity under iodide-rich conditions. Subsequently, vacancy defects and insulating ligands are cleared through introducing acid. Then this surface-cleaning process induces ligand exchange to further inhibit the nonradiative recombination and improve the electrical property of QDs. These QDs show a pure-red photoluminescence (PL) at 635 nm with the PL quantum yield (PLQY) of 99%. Finally, PeLEDs, which utilize these QDs, demonstrate a pure-red electroluminescence (EL) peak at 638 nm with a maximum external quantum efficiency (EQE) of 26.0% and an excellent half-lifetime (T50) of 490 min at an original luminance of 102 cd/m2.","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":null,"pages":null},"PeriodicalIF":11.4,"publicationDate":"2024-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141935176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Capacitance Measurement for Evaluating the Initial Top-Electrode-Damage-Induced Degradation of Organic Devices 电容测量用于评估有机器件顶部电极损坏引起的初始降解

IF 9.6 1区化学

ACS Materials Letters Pub Date : 2024-08-06 DOI: 10.1021/acsmaterialslett.4c0110310.1021/acsmaterialslett.4c01103

Chunqin Zhu, Guangrui Zhu, Ya Zhao, Ruichen Yi, Xiaoyuan Hou and Jiajun Qin*,

引用次数: 0

Efficient Synaptic Emulation and Ultralow Power Digital-Analog Conversion in Cellulose-Based Neural Devices through Molecular Polarization 通过分子极化实现纤维素神经器件中的高效突触模拟和超低功耗数模转换

IF 11.4 1区化学

ACS Materials Letters Pub Date : 2024-08-06 DOI: 10.1021/acsmaterialslett.4c01002

Kuan-Chang Chang, Yihua Xu, Mingge Wang, Zehui Peng, Dar-Jen Hsieh, Lei Li

{"title":"Efficient Synaptic Emulation and Ultralow Power Digital-Analog Conversion in Cellulose-Based Neural Devices through Molecular Polarization","authors":"Kuan-Chang Chang, Yihua Xu, Mingge Wang, Zehui Peng, Dar-Jen Hsieh, Lei Li","doi":"10.1021/acsmaterialslett.4c01002","DOIUrl":"https://doi.org/10.1021/acsmaterialslett.4c01002","url":null,"abstract":"Efficient hardware–cell communication is crucial in understanding cellular states and controlling cells, serving as a crucial pathway in advancing next-generation human–machine interfaces. Here, we propose an energy-efficient neural device based on natural cellulose, addressing limitations in conventional interface communication hardware, particularly concerning material biocompatibility and biological signal matching. The cellulose-based device effectively emulates the plasticity of biological synaptic connections and exhibits learning behavior under biograde voltage as low as 10 mV. Significantly, it demonstrates exceptional digital-to-analog conversion performance with a minimal power consumption of 0.1 nJ, facilitating efficient interface biological signal matching. Furthermore, a molecular-level model is introduced to elucidate the rotation of intramolecular polar bonds in cellulose induced by electrical stimulation. This rotation alters the material’s relative dielectric constant, unveiling the digital-to-analog conversion ability and neuro-like behavior. The biocompatible cellulose-based device efficiently emulates synapses with its low-power signal conversion, holding promise for effective biological signal matching in brain–machine interfaces.","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":null,"pages":null},"PeriodicalIF":11.4,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141935177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gas Adsorption Snapshots in Metal–Organic Frameworks Unveil the Impact of Pore Geometry on Hydrogen Storage 金属有机框架中的气体吸附快照揭示了孔隙几何形状对储氢的影响

IF 9.6 1区化学

ACS Materials Letters Pub Date : 2024-08-06 DOI: 10.1021/acsmaterialslett.4c0124610.1021/acsmaterialslett.4c01246

Nan Chieh Chiu, Andrzej Gładysiak, Ankit K. Yadav, Coset Abreu-Jaureguí, Alicia Manjón-Sanz, Cheng Li, Hongliang Huang, Joaquin Silvestre-Albero and Kyriakos C. Stylianou*,

{"title":"Gas Adsorption Snapshots in Metal–Organic Frameworks Unveil the Impact of Pore Geometry on Hydrogen Storage","authors":"Nan Chieh Chiu, Andrzej Gładysiak, Ankit K. Yadav, Coset Abreu-Jaureguí, Alicia Manjón-Sanz, Cheng Li, Hongliang Huang, Joaquin Silvestre-Albero and Kyriakos C. Stylianou*, ","doi":"10.1021/acsmaterialslett.4c0124610.1021/acsmaterialslett.4c01246","DOIUrl":"https://doi.org/10.1021/acsmaterialslett.4c01246https://doi.org/10.1021/acsmaterialslett.4c01246","url":null,"abstract":"Metal–organic frameworks (MOFs) are promising candidates for hydrogen (H2) storage. However, effective H2 storage in MOFs is challenging, because of weak adsorbent–adsorbate interactions. Optimizing the pore volume, size, and functionality in porous MOFs is crucial, but it is still unclear how to maximize H2 storage capacity while minimizing loading pressure. Herein, we investigate Al-TBAPy (H4TBAPy: 1,3,6,8-tetrakis(p-benzoic acid)pyrene), a low-density MOF, for H2 storage. Al-TBAPy features three interconnected pores (A–C), possesses a pore volume of 0.51 cm3/g, and demonstrates a H2 uptake of 22.5 mmol/g at 77 K and 100 bar. In situ deuterium (D2) gas loading neutron diffraction experiments reveal molecular-level insights into pore filling. Pores B and C exhibit high H2 affinity, while pore A, with a larger volume, takes up more H2 molecules. The collective properties of all pores and their interconnection result in a high deliverable gravimetric H2 capacity of 4.3 wt % under combined temperature and pressure swing conditions.","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":null,"pages":null},"PeriodicalIF":9.6,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142117329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Capacitance Measurement for Evaluating the Initial Top-Electrode-Damage-Induced Degradation of Organic Devices 电容测量用于评估有机器件顶部电极损坏引起的初始降解

IF 11.4 1区化学

ACS Materials Letters Pub Date : 2024-08-06 DOI: 10.1021/acsmaterialslett.4c01103

Chunqin Zhu, Guangrui Zhu, Ya Zhao, Ruichen Yi, Xiaoyuan Hou, Jiajun Qin

引用次数: 0