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Journal of Materials Chemistry B最新文献

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3D structured capillary cell suspensions aided by aqueous two-phase systems† 水基两相系统辅助下的三维结构毛细管细胞悬浮液。
IF 6.1 3区 医学
Journal of Materials Chemistry B Pub Date : 2024-10-08 DOI: 10.1039/D4TB01296H
Amro K. F. Dyab and Vesselin N. Paunov
{"title":"3D structured capillary cell suspensions aided by aqueous two-phase systems†","authors":"Amro K. F. Dyab and Vesselin N. Paunov","doi":"10.1039/D4TB01296H","DOIUrl":"10.1039/D4TB01296H","url":null,"abstract":"<p >We report a facile technique for 3D structuring of living cells by forming capillary cell suspensions based on an aqueous two-phase system (ATPS) of polyethylene glycol (PEG) and dextran (DEX) solutions. We demonstrate the formation of water-in-water (DEX-in-PEG) capillary bridges using concentrated suspensions of yeast cells which show enhanced rheological properties and distinctive 3D patterns. Capillary structured cell suspensions can potentially find applications in novel ways of 3D cell culturing, instant tissue engineering and many biomedical investigations.</p>","PeriodicalId":83,"journal":{"name":"Journal of Materials Chemistry B","volume":null,"pages":null},"PeriodicalIF":6.1,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/tb/d4tb01296h?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: Selenium nanoparticle-functionalized injectable chitosan/collagen hydrogels as a novel therapeutic strategy to enhance stem cell osteoblastic differentiation for bone regeneration 更正：硒纳米粒子功能化可注射壳聚糖/胶原蛋白水凝胶作为一种新型治疗策略，可增强干细胞成骨细胞分化，促进骨再生。
IF 6.1 3区 医学
Journal of Materials Chemistry B Pub Date : 2024-10-03 DOI: 10.1039/D4TB90161D
Khaled Alajmi, Matthew Hartford, Nakka Sharmila Roy, Anamitra Bhattacharya, Santanu Kaity, Brenton L. Cavanagh, Subhadeep Roy, Ciara M. Murphy and Kulwinder Kaur
{"title":"Correction: Selenium nanoparticle-functionalized injectable chitosan/collagen hydrogels as a novel therapeutic strategy to enhance stem cell osteoblastic differentiation for bone regeneration","authors":"Khaled Alajmi, Matthew Hartford, Nakka Sharmila Roy, Anamitra Bhattacharya, Santanu Kaity, Brenton L. Cavanagh, Subhadeep Roy, Ciara M. Murphy and Kulwinder Kaur","doi":"10.1039/D4TB90161D","DOIUrl":"10.1039/D4TB90161D","url":null,"abstract":"<p >Correction for ‘Selenium nanoparticle-functionalized injectable chitosan/collagen hydrogels as a novel therapeutic strategy to enhance stem cell osteoblastic differentiation for bone regeneration’ by Khaled Alajmi <em>et al.</em>, <em>J. Mater. Chem. B</em>, 2024, <strong>12</strong>, 9268–9282, https://doi.org/10.1039/D4TB00984C.</p>","PeriodicalId":83,"journal":{"name":"Journal of Materials Chemistry B","volume":null,"pages":null},"PeriodicalIF":6.1,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/tb/d4tb90161d?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142368054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: Surface modification of medical grade biomaterials by using a low-temperature-processed dual functional Ag–TiO2 coating for preventing biofilm formation 更正：使用低温加工的 Ag-TiO2 双功能涂层对医用生物材料进行表面改性，以防止生物膜的形成。
IF 6.1 3区 医学
Journal of Materials Chemistry B Pub Date : 2024-10-01 DOI: 10.1039/D4TB90157F
Lipi Pradhan, Sobhan Hazra, Satya Veer Singh, Bajrang, Anjali Upadhyay, Bhola Nath Pal and Sudip Mukherjee
{"title":"Correction: Surface modification of medical grade biomaterials by using a low-temperature-processed dual functional Ag–TiO2 coating for preventing biofilm formation","authors":"Lipi Pradhan, Sobhan Hazra, Satya Veer Singh, Bajrang, Anjali Upadhyay, Bhola Nath Pal and Sudip Mukherjee","doi":"10.1039/D4TB90157F","DOIUrl":"10.1039/D4TB90157F","url":null,"abstract":"<p >Correction for ‘Surface modification of medical grade biomaterials by using a low-temperature-processed dual functional Ag–TiO<small><sub>2</sub></small> coating for preventing biofilm formation’ by Lipi Pradhan <em>et al.</em>, <em>J. Mater. Chem. B</em>, 2024, https://doi.org/10.1039/D4TB00701H.</p>","PeriodicalId":83,"journal":{"name":"Journal of Materials Chemistry B","volume":null,"pages":null},"PeriodicalIF":6.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/tb/d4tb90157f?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contributors to the Journal of Materials Chemistry B Emerging Investigators 2024 collection 材料化学杂志》B 版《2024 年新兴研究者》文集的撰稿人。
IF 6.1 3区 医学
Journal of Materials Chemistry B Pub Date : 2024-09-30 DOI: 10.1039/D4TB90147A
{"title":"Contributors to the Journal of Materials Chemistry B Emerging Investigators 2024 collection","authors":"","doi":"10.1039/D4TB90147A","DOIUrl":"10.1039/D4TB90147A","url":null,"abstract":"<p >Our 2024 Emerging Investigators themed collections gather some of the best research being conducted by scientists in the early stages of their independent career. Each contributor was recommended as carrying out work with the potential to influence future directions in materials chemistry. Congratulations to all of the researchers featured, we hope you enjoy reading this collection.</p>","PeriodicalId":83,"journal":{"name":"Journal of Materials Chemistry B","volume":null,"pages":null},"PeriodicalIF":6.1,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: Bioreducible and acid-labile polydiethylenetriamines with sequential degradability for efficient transgelin-2 siRNA delivery 更正：可生物再现的酸性可降解聚二乙烯三胺，用于高效递送转胰岛素-2 siRNA。
IF 6.1 3区 医学
Journal of Materials Chemistry B Pub Date : 2024-09-24 DOI: 10.1039/D3TB90091F
Pengchong Wang, Yan Yan, Ying Sun, Rui Zhang, Chuanchuan Huo, Lu Li, Ke Wang, Yalin Dong and Jianfeng Xing
{"title":"Correction: Bioreducible and acid-labile polydiethylenetriamines with sequential degradability for efficient transgelin-2 siRNA delivery","authors":"Pengchong Wang, Yan Yan, Ying Sun, Rui Zhang, Chuanchuan Huo, Lu Li, Ke Wang, Yalin Dong and Jianfeng Xing","doi":"10.1039/D3TB90091F","DOIUrl":"10.1039/D3TB90091F","url":null,"abstract":"<p >Correction for ‘Bioreducible and acid-labile polydiethylenetriamines with sequential degradability for efficient transgelin-2 siRNA delivery’ by Pengchong Wang <em>et al.</em>, <em>J. Mater. Chem. B</em>, 2019, <strong>7</strong>, 6994–7005, https://doi.org/10.1039/C9TB01183H.</p>","PeriodicalId":83,"journal":{"name":"Journal of Materials Chemistry B","volume":null,"pages":null},"PeriodicalIF":6.1,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/tb/d3tb90091f?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142309499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: Development and characterization of a novel poly(N-isopropylacrylamide)-based thermoresponsive photoink and its applications in DLP bioprinting 更正：新型聚(N-异丙基丙烯酰胺)热致伸缩性光墨水的开发和表征及其在 DLP 生物打印中的应用。
IF 6.1 3区 医学
Journal of Materials Chemistry B Pub Date : 2024-09-24 DOI: 10.1039/D4TB90152E
Kalindu D. C. Perera, Sophia M. Boiani, Alexandra K. Vasta, Katherine J. Messenger, Sabrina Delva and Jyothi U. Menon
{"title":"Correction: Development and characterization of a novel poly(N-isopropylacrylamide)-based thermoresponsive photoink and its applications in DLP bioprinting","authors":"Kalindu D. C. Perera, Sophia M. Boiani, Alexandra K. Vasta, Katherine J. Messenger, Sabrina Delva and Jyothi U. Menon","doi":"10.1039/D4TB90152E","DOIUrl":"10.1039/D4TB90152E","url":null,"abstract":"<p >Correction for ‘Development and characterization of a novel poly(<em>N</em>-isopropylacrylamide)-based thermoresponsive photoink and its applications in DLP bioprinting’ by Kalindu D. C. Perera <em>et al.</em>, <em>J. Mater. Chem. B</em>, 2024, https://doi.org/10.1039/D4TB00682H.</p>","PeriodicalId":83,"journal":{"name":"Journal of Materials Chemistry B","volume":null,"pages":null},"PeriodicalIF":6.1,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11420647/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142309500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tissue adhesives based on chitosan for biomedical applications 基于壳聚糖的组织粘合剂在生物医学中的应用
IF 6.331 3区 医学
Journal of Materials Chemistry B Pub Date : 2024-09-18 DOI: 10.1039/d4tb01362j
Jihyun Youn, Kapil D. Patel, Adam W. Perriman, Jung-Suk Sung, Madhumita Patel, Louis-S. Bouchard, Rajkumar Patel
{"title":"Tissue adhesives based on chitosan for biomedical applications","authors":"Jihyun Youn, Kapil D. Patel, Adam W. Perriman, Jung-Suk Sung, Madhumita Patel, Louis-S. Bouchard, Rajkumar Patel","doi":"10.1039/d4tb01362j","DOIUrl":"https://doi.org/10.1039/d4tb01362j","url":null,"abstract":"Chitosan bio-adhesives bond strongly with various biological tissues, such as skin, mucosa, and internal organs. Their adhesive ability arises from amino acid and hydroxyl groups in chitosan, facilitating interactions with tissue surfaces through chemical (ionic, covalent, and hydrogen) and physical (chain entanglement) bonding. As non-toxic, biodegradable, and biocompatible materials, chitosan bio-adhesives are a safe option for medical therapies. They are particularly suitable for drug delivery, wound healing, and tissue regeneration. In this review, we address chitosan-based bio-adhesives and the mechanisms associated with them. We also discuss different chitosan composite-based bio-adhesives and their biomedical applications in wound healing, drug delivery, hemostasis, and tissue regeneration. Finally, challenges and future perspectives for the clinical use of chitosan-based bio-adhesives are discussed.","PeriodicalId":83,"journal":{"name":"Journal of Materials Chemistry B","volume":null,"pages":null},"PeriodicalIF":6.331,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142248619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development and evaluation of 3D composite scaffolds with piezoelectricity and biofactor synergy for enhanced articular cartilage regeneration† 开发和评估具有压电性和生物因子协同作用的三维复合支架，促进关节软骨再生
IF 6.1 3区 医学
Journal of Materials Chemistry B Pub Date : 2024-09-18 DOI: 10.1039/D4TB01319K
Bowen Xie, Hebin Ma, Fengyuan Yang, Hongguang Chen, Ya’nan Guo, Hongxing Zhang, Tengfei Li, Xiaogang Huang, Yantao Zhao, Xiaojie Li and Junjie Du
{"title":"Development and evaluation of 3D composite scaffolds with piezoelectricity and biofactor synergy for enhanced articular cartilage regeneration†","authors":"Bowen Xie, Hebin Ma, Fengyuan Yang, Hongguang Chen, Ya’nan Guo, Hongxing Zhang, Tengfei Li, Xiaogang Huang, Yantao Zhao, Xiaojie Li and Junjie Du","doi":"10.1039/D4TB01319K","DOIUrl":"10.1039/D4TB01319K","url":null,"abstract":"<p >The inability of articular cartilage to self-repair following injuries frequently precipitates osteoarthritis, profoundly affecting patients' quality of life. Given the limitations inherent in current clinical interventions, an urgent need exists for more effective cartilage regeneration methodologies. Previous studies have underscored the potential of electrical stimulation in cartilage repair, thus motivating the investigation of innovative strategies. The present study introduces a three-dimensional scaffold fabricated through a composite technique that leverages the synergy between piezoelectricity and biofactors to enhance cartilage repair. This scaffold is composed of polylactic acid (PLLA) and barium titanate (BT) for piezoelectric stimulation and at the bottom with a collagen-coated layer infused with fibroblast growth factor-18 (FGF-18) for biofactor delivery. Designed to emulate the properties of natural cartilage, the scaffold enables controlled generation of piezoelectric charges and the sustained release of biofactors. <em>In vitro</em> tests confirm that the scaffold promotes chondrocyte proliferation, matrix hyperplasia, cellular migration, and the expression of genes associated with cartilage formation. Moreover, <em>in vivo</em> studies on rabbits have illustrated its efficacy in catalyzing the <em>in situ</em> regeneration of articular cartilage defects and remodeling the extracellular matrix. This innovative approach offers significant potential for enhancing cartilage repair and holds profound implications for regenerative medicine.</p>","PeriodicalId":83,"journal":{"name":"Journal of Materials Chemistry B","volume":null,"pages":null},"PeriodicalIF":6.1,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/tb/d4tb01319k?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142248576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Photopatterning of conductive hydrogels which exhibit tissue-like properties† 具有类似组织特性的导电水凝胶的光图案化
IF 6.1 3区 医学
Journal of Materials Chemistry B Pub Date : 2024-09-16 DOI: 10.1039/D4TB00807C
Léo Sifringer, Lina De Windt, Stéphane Bernhard, Giulia Amos, Blandine Clément, Jens Duru, Mark W. Tibbitt and Christina M. Tringides
{"title":"Photopatterning of conductive hydrogels which exhibit tissue-like properties†","authors":"Léo Sifringer, Lina De Windt, Stéphane Bernhard, Giulia Amos, Blandine Clément, Jens Duru, Mark W. Tibbitt and Christina M. Tringides","doi":"10.1039/D4TB00807C","DOIUrl":"10.1039/D4TB00807C","url":null,"abstract":"<p >Hydrogels are three-dimensional, highly tunable material systems that can match the properties of extracellular matrices. In addition to being widely used to grow and modulate cell behavior, hydrogels can be made conductive to further modulate electrically active cells, such as neurons, and even incorporated into multielectrode arrays to interface with tissues. To enable conductive hydrogels, graphene flakes can be mechanically suspended into a hydrogel precursor. The conductivity of the hydrogel can be increased by increasing the weight percentage of graphene flakes in the precursor while maintaining the mechanical properties of the formed gel similar to the properties of neural tissue. By using a photocrosslinkable hydrogel matrix, such as gelatin methacrylate, with a photoabsorber, the conductive precursor solutions can be crosslinked into predefined complex patterns. Finally, the formulations can be used to support the growth of sensory neurons, derived from human induced pluripotent stem cells, for more than 7 weeks while the neurons remain viable. These scaffolds can be patterned into components of multielectrode arrays, to enable ultrasoft electrodes with tissue-matched properties for further interactions, both <em>in vitro</em> and <em>in vivo</em>, with the nervous systems.</p>","PeriodicalId":83,"journal":{"name":"Journal of Materials Chemistry B","volume":null,"pages":null},"PeriodicalIF":6.1,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/tb/d4tb00807c?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142248575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In vivo safety evaluation and tracing of arginylglycylaspartic acid-engineered phage nanofiber in murine model† 精氨酰甘氨酰天冬氨酸工程噬菌体纳米纤维在小鼠模型中的体内安全性评估和追踪研究
IF 6.1 3区 医学
Journal of Materials Chemistry B Pub Date : 2024-09-16 DOI: 10.1039/D4TB00823E
Kshitiz Raj Shrestha, Sehoon Kim, Anna Jo, Murali Ragothaman and So Young Yoo
{"title":"In vivo safety evaluation and tracing of arginylglycylaspartic acid-engineered phage nanofiber in murine model†","authors":"Kshitiz Raj Shrestha, Sehoon Kim, Anna Jo, Murali Ragothaman and So Young Yoo","doi":"10.1039/D4TB00823E","DOIUrl":"10.1039/D4TB00823E","url":null,"abstract":"<p >The engineered phage YSY184, mimicking the extracellular matrix nanofiber, effectively promotes stem cell differentiation and angiogenesis. This study evaluated its safety in a mouse model, monitoring weight, immunogenicity, spleen immune responses, and macrophage infiltration. Rapid clearance of YSY184 was observed, with peak tissue presence within three hours, significantly reduced by 24 hours, and negligible after one month. No adverse physiological or pathological effects were detected post-administration, affirming YSY184's safety and underscore its potential for therapeutic use, warranting further clinical exploration.</p>","PeriodicalId":83,"journal":{"name":"Journal of Materials Chemistry B","volume":null,"pages":null},"PeriodicalIF":6.1,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142248627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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