ACS Materials Letters最新文献_第2页

Edge-Plane-Selective Formation of Mn Vacancies in β-Na0.7MnO2+y for Air-Stable Cathode Materials in Sodium-Ion Batteries

IF 9.6 1区化学

ACS Materials Letters Pub Date : 2025-02-14 DOI: 10.1021/acsmaterialslett.4c0264210.1021/acsmaterialslett.4c02642

Hyeongi Kim, Chang-Eui Yang, Sukhyung Lee, Byunghyun Yun, Taehun Kim, Suyeon Lee, Joon Ha Chang, Beom Tak Na, Hochun Lee, Youngjin Kim* and Kyu Tae Lee*,

{"title":"Edge-Plane-Selective Formation of Mn Vacancies in β-Na0.7MnO2+y for Air-Stable Cathode Materials in Sodium-Ion Batteries","authors":"Hyeongi Kim, Chang-Eui Yang, Sukhyung Lee, Byunghyun Yun, Taehun Kim, Suyeon Lee, Joon Ha Chang, Beom Tak Na, Hochun Lee, Youngjin Kim* and Kyu Tae Lee*, ","doi":"10.1021/acsmaterialslett.4c0264210.1021/acsmaterialslett.4c02642","DOIUrl":"https://doi.org/10.1021/acsmaterialslett.4c02642https://doi.org/10.1021/acsmaterialslett.4c02642","url":null,"abstract":"Manganese-based P2-type NaxMnO2+y, particularly β-Na0.7MnO2+y, exhibit high reversible capacity but are prone to stability issues, especially hydration-induced degradation when exposed to air. Herein, a significant improvement in the air stability of β-Na0.7MnO2+y cathodes is achieved through a selective transition of their edge planes to α-Na0.7MnO2+z. When β-Na0.7MnO2+y particles are oxidized at a relatively low temperature (350 °C), oxygen is selectively inserted at the edge planes due to the higher energy barrier for oxygen insertion at the basal planes compared with the edge planes. This mild oxidation selectively locally creates manganese vacancies near the edge plane surface, promoting the exclusive formation of α-Na0.7MnO2+z on the edge surface. The α-Na0.7MnO2+z nanolayers on the edge planes effectively suppress H2O insertion during air exposure, eventually mitigating the phase transition of β-Na0.7MnO2+y to NaγMnO2·δH2O birnessite during storage. Moreover, this plane-selective formation of α-Na0.7MnO2+z enhances the electrochemical performance of β-Na0.7MnO2+y, such as stable capacity retention.","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":"7 3","pages":"1003–1011 1003–1011"},"PeriodicalIF":9.6,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143528535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Remarkable Piezochromism and Pressure-Induced Blue Emission Enhancement in Complex-Unit Copper Halides

IF 9.6 1区化学

ACS Materials Letters Pub Date : 2025-02-14 DOI: 10.1021/acsmaterialslett.4c0255610.1021/acsmaterialslett.4c02556

Ming Cong, Qiushuang Li, Xuchen Wang, Jiayi Yang, Yongguang Li, Le Ye, Guanjun Xiao* and Bo Zou,

{"title":"Remarkable Piezochromism and Pressure-Induced Blue Emission Enhancement in Complex-Unit Copper Halides","authors":"Ming Cong, Qiushuang Li, Xuchen Wang, Jiayi Yang, Yongguang Li, Le Ye, Guanjun Xiao* and Bo Zou, ","doi":"10.1021/acsmaterialslett.4c0255610.1021/acsmaterialslett.4c02556","DOIUrl":"https://doi.org/10.1021/acsmaterialslett.4c02556https://doi.org/10.1021/acsmaterialslett.4c02556","url":null,"abstract":"Piezochromic luminescent materials (PLMs) exhibit potential applications in pressure sensing, anticounterfeiting, and optical memory. However, balancing a wide range of emission shifts with high pressure-sensitivity remains a challenge. Here, we achieved a considerable blue-shift piezochromism of 187 nm in zero-dimensional (0D) copper halide (TPA)2Cu4Br6 (TPA = Tetrapropylammonium), with a pressure coefficient over 80 nm/GPa below 10 kbar. Structural analysis confirmed that increased pressure deepened the high-energy self-trapped excitons (STEs) and disrupted the orderly arrangement of the [Cu4Br6]2– clusters. These two factors collectively diminished the interaction between STEs and depressed the formation of low-energy STEs, resulting in a significant blue shift in emission. Moreover, the decreased energy loss resulting from depressed phonon–phonon interaction led to a high photoluminescence quantum yield (PLQY) which remained over 70% during the blue-shift process and enabled the enhanced display performance as PLMs. This study demonstrated a highly sensitive PLM and revealed photophysical mechanism regarding the configuration and arrangement of complex clusters.","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":"7 3","pages":"996–1002 996–1002"},"PeriodicalIF":9.6,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143528536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhanced Exciton Utilization through Multichannel High-Lying Reverse Intersystem Crossing Enabled by Degenerate Strategy for High-Performance Ultraviolet OLED

IF 9.6 1区化学

ACS Materials Letters Pub Date : 2025-02-14 DOI: 10.1021/acsmaterialslett.4c0233610.1021/acsmaterialslett.4c02336

Haoyuan Qi, Hao Huang, Shuyao He, Shengnan Wang, Ling Peng, Yuchao Liu, Shanfeng Xue, Dongge Ma, Shian Ying* and Shouke Yan*,

{"title":"Enhanced Exciton Utilization through Multichannel High-Lying Reverse Intersystem Crossing Enabled by Degenerate Strategy for High-Performance Ultraviolet OLED","authors":"Haoyuan Qi, Hao Huang, Shuyao He, Shengnan Wang, Ling Peng, Yuchao Liu, Shanfeng Xue, Dongge Ma, Shian Ying* and Shouke Yan*, ","doi":"10.1021/acsmaterialslett.4c0233610.1021/acsmaterialslett.4c02336","DOIUrl":"https://doi.org/10.1021/acsmaterialslett.4c02336https://doi.org/10.1021/acsmaterialslett.4c02336","url":null,"abstract":"Ultraviolet (UV) organic light-emitting diodes (OLEDs) utilizing hybridized local and charge transfer (HLCT) emitters exhibit significant potential, where a favorable high-lying reverse intersystem crossing process is pivotal for attaining both triplet exciton utilization and low efficiency roll-off. Herein, a degenerate strategy induced by multiple donor moieties is proposed to design and synthesize a highly efficient UV HLCT fluorophore, namely 3,6-mCPCNC3. Comparatively, it not only demonstrates exceptional morphological stability and a rapid radiative decay rate but also enriches the reverse intersystem crossing channels from high-lying triplet to singlet states. Consequently, the 3,6-mCPCNC3-based device exhibits an astonishing external quantum efficiency (EQE) of 8.73% coupled with an impressive exciton utilization efficiency of 86.3%. Even at a luminance of 1000 cd m–2, the EQE still maintains a remarkable value of 8.29%, showcasing an exceptionally low efficiency roll-off. Remarkably, the device emits stable UV light with a peak wavelength at 389 nm and a narrow full-width half-maximum of 41 nm, corresponding to the color coordinates (0.161, 0.021). The record-high EQE achieved at 1000 cd m–2 represents the state-of-the-art efficiency among the currently reported UV-OLEDs operating at high luminance levels.","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":"7 3","pages":"1019–1027 1019–1027"},"PeriodicalIF":9.6,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143528571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lead-Doped Cesium Manganese Halide Perovskite Nanocrystals for Light-Emitting Diodes: Room-Temperature Synthesis, Energy Transfer, and Phase Modulating 用于发光二极管的铅掺杂卤化铯锰过氧化物纳米晶体：室温合成、能量转移和相位调制

IF 9.6 1区化学

ACS Materials Letters Pub Date : 2025-02-14 DOI: 10.1021/acsmaterialslett.4c0222410.1021/acsmaterialslett.4c02224

Jiejun Ren*, Longyun Liu, Huiping Liu, Xiaopeng Zhou, Jiale Li, Fan Liu*, Liangjun Chen, Guoping Yan and Yuhua Wang*,

{"title":"Lead-Doped Cesium Manganese Halide Perovskite Nanocrystals for Light-Emitting Diodes: Room-Temperature Synthesis, Energy Transfer, and Phase Modulating","authors":"Jiejun Ren*, Longyun Liu, Huiping Liu, Xiaopeng Zhou, Jiale Li, Fan Liu*, Liangjun Chen, Guoping Yan and Yuhua Wang*, ","doi":"10.1021/acsmaterialslett.4c0222410.1021/acsmaterialslett.4c02224","DOIUrl":"https://doi.org/10.1021/acsmaterialslett.4c02224https://doi.org/10.1021/acsmaterialslett.4c02224","url":null,"abstract":"Lead halide perovskite nanocrystals (NCs) have been attracting the interest of researchers due to their outstanding photophysical properties. However, their practical application is greatly hindered by lead toxicity. Despite series of lead-free NCs being investigated, they generally exhibit broadband emission and poor color tunability. Herein, we proposed a facile room temperature synthesis of highly efficient color-tunable CsMnBr3:Pb2+ NCs. Ascribing to the efficient energy transfer from [PbBr6]4– to Mn2+, the photoluminescent quantum yield (PLQY) of CsMnBr3:Pb2+ NCs reaches up to 83.6%, which is 12.5 times that of undoped CsMnBr3 NCs. More interestingly, the red-emitting CsMnBr3:Pb2+ NCs could be easily transformed to green-emitting Cs3MnBr5:Pb2+ NCs through coordination modulating. The color-tunable CsMnBr3:Pb2+ NCs and Cs3MnBr5:Pb2+ NCs possess high PLQY and high color purity, demonstrating great application potential in optoelectronic fields.","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":"7 3","pages":"1028–1034 1028–1034"},"PeriodicalIF":9.6,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143528518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

F-Doped Enhanced Dual Reduction Center Metal–Organic Framework for Aqueous Aluminum Ion Batteries

IF 9.6 1区化学

ACS Materials Letters Pub Date : 2025-02-13 DOI: 10.1021/acsmaterialslett.4c0267710.1021/acsmaterialslett.4c02677

Hanqing Gu, Zhibao Wang, Wenming Zhang* and Zhanyu Li*,

{"title":"F-Doped Enhanced Dual Reduction Center Metal–Organic Framework for Aqueous Aluminum Ion Batteries","authors":"Hanqing Gu, Zhibao Wang, Wenming Zhang* and Zhanyu Li*, ","doi":"10.1021/acsmaterialslett.4c0267710.1021/acsmaterialslett.4c02677","DOIUrl":"https://doi.org/10.1021/acsmaterialslett.4c02677https://doi.org/10.1021/acsmaterialslett.4c02677","url":null,"abstract":"Metal–organic frameworks (MOFs) with characteristics of metal ion hosts and organic ligand guests show promising applications in aqueous aluminum ion batteries (AAIBs). However, the sluggish kinetics and poor stability have detrimental effects on their practical application. Herein, an F-doped manganese-based metal–organic framework (Mn-MOF-74) was synthesized via a hydrothermal method. Mn-MOF-74 provides additional redox sites. Due to the high electronegativity of F and the high bond energy of C–F, the F-doping strategy has successfully improved the kinetics and stability. Electrochemical analysis and density functional theory (DFT) calculations jointly demonstrate the activation process of Mn-MOF-74. In addition, the energy storage mechanism has been systematically investigated by ex situ characterization. The organic linker provides additional active sites in which C═O and C–O undergo reversible changes. This work provides not only a feasible way to improve cycling stability but also a deeper understanding of the reaction mechanism related to MOFs in AAIBs.","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":"7 3","pages":"974–980 974–980"},"PeriodicalIF":9.6,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143528492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Kinetic-Enhanced Morphology Control of Covalent Organic Frameworks via a “Freezing–Thawing” Pretreatment Strategy 通过 "冻结-解冻 "预处理策略实现共价有机框架的动力学增强形态控制

IF 9.6 1区化学

ACS Materials Letters Pub Date : 2025-02-13 DOI: 10.1021/acsmaterialslett.4c0247010.1021/acsmaterialslett.4c02470

Jie Zhang, Yue Qi, Yingdan Zhang, Ningning He, Yingdi Zou, Zhiying Fan, Chan Deng, Guohong Tao, Lijian Ma and Yang Li*,

{"title":"Kinetic-Enhanced Morphology Control of Covalent Organic Frameworks via a “Freezing–Thawing” Pretreatment Strategy","authors":"Jie Zhang, Yue Qi, Yingdan Zhang, Ningning He, Yingdi Zou, Zhiying Fan, Chan Deng, Guohong Tao, Lijian Ma and Yang Li*, ","doi":"10.1021/acsmaterialslett.4c0247010.1021/acsmaterialslett.4c02470","DOIUrl":"https://doi.org/10.1021/acsmaterialslett.4c02470https://doi.org/10.1021/acsmaterialslett.4c02470","url":null,"abstract":"Modulating the reaction reversibility can help escape kinetic traps and effectively regulate the morphology of covalent organic frameworks (COFs). However, most current approaches focus primarily on thermodynamic factors with limited research on enhancing kinetic reaction pathways. Herein, we introduce a novel strategy that combines a “freezing–thawing” pretreatment with conventional solvothermal synthesis to enhance kinetic pathways in COF-366 synthesis. This pretreatment effectively limits the degree of monomer polymerization, facilitating structural repairs during subsequent high-temperature reactions, and slows the polymerization rate, leading to a higher yield of kinetic products. Consequently, K-COF-366 synthesized through our kinetic-enhanced method exhibits hierarchically ordered nanosheet morphology, in contrast to the irregular agglomerates produced of T-COF-366 by traditional methods. These K-COF-366 nanosheets are well-suited for developing self-supported continuous membrane materials. They were obtained through vacuum-assisted filtration and functionally modified with pyruvic acid to create K-COF-366-COOH membranes, which demonstrate excellent separation performance for uranium and thorium.","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":"7 3","pages":"981–989 981–989"},"PeriodicalIF":9.6,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143528468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Mechanical Pressure on the Ionic Conductivity of Sodium Dodecahydrido-closo-dodecaborate 机械压力对十二水合十二硼酸钠离子电导率的影响

IF 9.6 1区化学

ACS Materials Letters Pub Date : 2025-02-13 DOI: 10.1021/acsmaterialslett.4c0215310.1021/acsmaterialslett.4c02153

Lasse R. Kristensen, Gerrit J. Herrmann, Jørgen Skibsted and Torben R. Jensen*,

{"title":"Effect of Mechanical Pressure on the Ionic Conductivity of Sodium Dodecahydrido-closo-dodecaborate","authors":"Lasse R. Kristensen, Gerrit J. Herrmann, Jørgen Skibsted and Torben R. Jensen*, ","doi":"10.1021/acsmaterialslett.4c0215310.1021/acsmaterialslett.4c02153","DOIUrl":"https://doi.org/10.1021/acsmaterialslett.4c02153https://doi.org/10.1021/acsmaterialslett.4c02153","url":null,"abstract":"To optimize the performance of solid-state batteries, careful control of the material properties is essential. Solid-state batteries require significant mechanical pressure during assembly and cycling to ensure intimate contact and stability of the electrochemical cell. Here we show that mechanical pressure can induce a polymorphic transition (P21/c → Pbca) of sodium dodecahydrido-closo-dodecaborate, Na2B12H12, which increases both the boron dynamics and the ionic conductivity. Heating mechanically pressed samples above 65 °C results in full conversion back to the initial polymorph (P21/c), along with a reduction of one order of magnitude in ionic conductivity, which is consistent with the as-synthesized Na2B12H12. This work emphasizes the important role that postsynthesis treatment can have on the ionic conductivity, the activation energy, and the texture of solid electrolytes.","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":"7 3","pages":"990–995 990–995"},"PeriodicalIF":9.6,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143528469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Emerging Hydrophobized Surfaces for Rapid Fabrication of 3D Tumor Models

IF 9.6 1区化学

ACS Materials Letters Pub Date : 2025-02-11 DOI: 10.1021/acsmaterialslett.4c0228010.1021/acsmaterialslett.4c02280

Maria V. Monteiro, Mariana T. Carvalho, Beatriz S. Moura, Vítor M. Gaspar* and João F. Mano*,

{"title":"Emerging Hydrophobized Surfaces for Rapid Fabrication of 3D Tumor Models","authors":"Maria V. Monteiro, Mariana T. Carvalho, Beatriz S. Moura, Vítor M. Gaspar* and João F. Mano*, ","doi":"10.1021/acsmaterialslett.4c0228010.1021/acsmaterialslett.4c02280","DOIUrl":"https://doi.org/10.1021/acsmaterialslett.4c02280https://doi.org/10.1021/acsmaterialslett.4c02280","url":null,"abstract":"The development of hydrophobized platforms to build up tailored 3D in vitro tumor models, for screening anticancer therapies, is currently gaining remarkable momentum. Such focus is related to the unique water repellent properties of hydrophobic surfaces, which promote the production of spherically structured models and cells’ self-assembly into dense 3D agglomerates. Considering this potential, herein we showcase the most recent advances in precision engineered hydrophobized surfaces and discuss their valuable features for establishing 3D in vitro tumor models with reproducible size, morphology, and biochemical/biophysical hallmarks. An in-depth overview of disruptive studies employing hydrophobized surfaces for 3D miniaturized tumor models fabrication and preclinical drug screening is provided, along with a discussion of the benefits and drawbacks of each approach. Overall, we envision that hydrophobized platforms evolution will contribute to the generation of 3D in vitro models that more accurately recapitulate features of human tumors and that are also easily scalable for high-throughput/high-content imaging platforms.","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":"7 3","pages":"961–973 961–973"},"PeriodicalIF":9.6,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143528459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The COF Space: Materials Features, Gas Adsorption, and Separation Performances Assessed by Machine Learning COF 空间：通过机器学习评估材料特征、气体吸附和分离性能

IF 9.6 1区化学

ACS Materials Letters Pub Date : 2025-02-11 DOI: 10.1021/acsmaterialslett.4c0259410.1021/acsmaterialslett.4c02594

Gokhan Onder Aksu, and , Seda Keskin*,

{"title":"The COF Space: Materials Features, Gas Adsorption, and Separation Performances Assessed by Machine Learning","authors":"Gokhan Onder Aksu,  and , Seda Keskin*, ","doi":"10.1021/acsmaterialslett.4c0259410.1021/acsmaterialslett.4c02594","DOIUrl":"https://doi.org/10.1021/acsmaterialslett.4c02594https://doi.org/10.1021/acsmaterialslett.4c02594","url":null,"abstract":"Covalent organic frameworks (COFs) are promising materials for gas adsorption; however, only a small number of COFs has been studied for a few types of gas separations to date. To unlock the full potential of the COF space, composed of 69 784 different types of materials, we studied the adsorption of five important gas molecules, CO2, CH4, H2, N2, and O2 in COFs at various pressures combining high-throughput molecular simulations and machine learning. Adsorbent performances of COFs were then explored for industrially critical separations, such as CO2/CH4, CO2/H2, CO2/N2, CH4/H2, CH4/N2, and O2/N2. The key structural and chemical properties of the most promising adsorbents were revealed. Our work offers the most extensive dataset produced for COFs in the literature composed of ∼4.3 million data points for all synthesized and hypothetical COFs’ structural, chemical, and energetic features; gas adsorption properties; and selectivities to facilitate the materials discovery.","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":"7 3","pages":"954–960 954–960"},"PeriodicalIF":9.6,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsmaterialslett.4c02594","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143528460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Telomerase Triggered Strand Displacement Cycles at DNA Tetrahedron Layer for Highly Sensitive Electrochemical Biosensing

IF 9.6 1区化学

ACS Materials Letters Pub Date : 2025-02-10 DOI: 10.1021/acsmaterialslett.4c0241410.1021/acsmaterialslett.4c02414

Xifeng Chen, Jiarong Guo, Hua Chai, Yuguo Tang and Peng Miao*,

{"title":"Telomerase Triggered Strand Displacement Cycles at DNA Tetrahedron Layer for Highly Sensitive Electrochemical Biosensing","authors":"Xifeng Chen, Jiarong Guo, Hua Chai, Yuguo Tang and Peng Miao*, ","doi":"10.1021/acsmaterialslett.4c0241410.1021/acsmaterialslett.4c02414","DOIUrl":"https://doi.org/10.1021/acsmaterialslett.4c02414https://doi.org/10.1021/acsmaterialslett.4c02414","url":null,"abstract":"Accurate analysis of human telomerase is of great significance for the early diagnosis and therapy of cancers. In this study, we have designed a novel toehold-mediated strand displacement amplification strategy for the electrochemical detection of telomerase. A one-pot reaction is involved at the top of tetrahedral DNA nanostructures, which were previously immobilized at the electrode interface. Telomerase extended product first initiates strand displacement cycles, which further lead to the localization of electrochemical species. The level of target telomerase can thus be determined by measurement of the electrochemical response with high sensitivity. Furthermore, this approach is applicable for the screening of inhibitors and successfully distinguishes relative telomerase activities among different cells. It circumvents the drawbacks of traditional telomerase assays and exhibits appealing features like convenient operation, high sensitivity, and selectivity. It is demonstrated to be a promising tool for applications in telomerase-associated early diagnosis and antitumor drug screening.","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":"7 3","pages":"947–953 947–953"},"PeriodicalIF":9.6,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143528457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0