ACS Applied Polymer Materials最新文献

{"title":"The role of mitochondria in tumor metastasis and advances in mitochondria-targeted cancer therapy.","authors":"Fanglu Chen, Yucheng Xue, Wenkan Zhang, Hao Zhou, Zhiyi Zhou, Tao Chen, Eloy YinWang, Hengyuan Li, Zhaoming Ye, Junjie Gao, Shengdong Wang","doi":"10.1007/s10555-024-10211-9","DOIUrl":"10.1007/s10555-024-10211-9","url":null,"abstract":"<p><p>Mitochondria are central actors in diverse physiological phenomena ranging from energy metabolism to stress signaling and immune modulation. Accumulating scientific evidence points to the critical involvement of specific mitochondrial-associated events, including mitochondrial quality control, intercellular mitochondrial transfer, and mitochondrial genetics, in potentiating the metastatic cascade of neoplastic cells. Furthermore, numerous recent studies have consistently emphasized the highly significant role mitochondria play in coordinating the regulation of tumor-infiltrating immune cells and immunotherapeutic interventions. This review provides a comprehensive and rigorous scholarly investigation of this subject matter, exploring the intricate mechanisms by which mitochondria contribute to tumor metastasis and examining the progress of mitochondria-targeted cancer therapies.</p>","PeriodicalId":7,"journal":{"name":"ACS Applied Polymer Materials","volume":" ","pages":"1419-1443"},"PeriodicalIF":7.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11554835/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142280529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An adaptive enhanced human memory algorithm for multi-level image segmentation for pathological lung cancer images.","authors":"Mahmoud Abdel-Salam, Essam H Houssein, Marwa M Emam, Nagwan Abdel Samee, Mona M Jamjoom, Gang Hu","doi":"10.1016/j.compbiomed.2024.109272","DOIUrl":"10.1016/j.compbiomed.2024.109272","url":null,"abstract":"<p><p>Lung cancer is a critical health issue that demands swift and accurate diagnosis for effective treatment. In medical imaging, segmentation is crucial for identifying and isolating regions of interest, which is essential for precise diagnosis and treatment planning. Traditional metaheuristic-based segmentation methods often struggle with slow convergence speed, poor optimized thresholds results, balancing exploration and exploitation, leading to suboptimal performance in the multi-thresholding segmenting of lung cancer images. This study presents ASG-HMO, an enhanced variant of the Human Memory Optimization (HMO) algorithm, selected for its simplicity, versatility, and minimal parameters. Although HMO has never been applied to multi-thresholding image segmentation, its characteristics make it ideal to improve pathology lung cancer image segmentation. The ASG-HMO incorporating four innovative strategies that address key challenges in the segmentation process. Firstly, the enhanced adaptive mutualism phase is proposed to balance exploration and exploitation to accurately delineate tumor boundaries without getting trapped in suboptimal solutions. Second, the spiral motion strategy is utilized to adaptively refines segmentation solutions by focusing on both the overall lung structure and the intricate tumor details. Third, the gaussian mutation strategy introduces diversity in the search process, enabling the exploration of a broader range of segmentation thresholds to enhance the accuracy of segmented regions. Finally, the adaptive t-distribution disturbance strategy is proposed to help the algorithm avoid local optima and refine segmentation in later stages. The effectiveness of ASG-HMO is validated through rigorous testing on the IEEE CEC'17 and CEC'20 benchmark suites, followed by its application to multilevel thresholding segmentation in nine histopathology lung cancer images. In these experiments, six different segmentation thresholds were tested, and the algorithm was compared to several classical, recent, and advanced segmentation algorithms. In addition, the proposed ASG-HMO leverages 2D Renyi entropy and 2D histograms to enhance the precision of the segmentation process. Quantitative result analysis in pathological lung cancer segmentation showed that ASG-HMO achieved superior maximum Peak Signal-to-Noise Ratio (PSNR) of 31.924, Structural Similarity Index Measure (SSIM) of 0.919, Feature Similarity Index Measure (FSIM) of 0.990, and Probability Rand Index (PRI) of 0.924. These results indicate that ASG-HMO significantly outperforms existing algorithms in both convergence speed and segmentation accuracy. This demonstrates the robustness of ASG-HMO as a framework for precise segmentation of pathological lung cancer images, offering substantial potential for improving clinical diagnostic processes.</p>","PeriodicalId":7,"journal":{"name":"ACS Applied Polymer Materials","volume":"183 ","pages":"109272"},"PeriodicalIF":4.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The efficient classification of breast cancer on low-power IoT devices: A study on genetically evolved U-Net.","authors":"Mohit Agarwal, Amit Kumar Dwivedi, Dibyanarayan Hazra, Preeti Sharma, Suneet Kumar Gupta, Deepak Garg","doi":"10.1016/j.compbiomed.2024.109296","DOIUrl":"10.1016/j.compbiomed.2024.109296","url":null,"abstract":"<p><p>Breast cancer is the most common cancer among women, and in some cases, it also affects men. Since early detection allows for proper treatment, automated data classification is essential. Although such classifications provide timely results, the resource requirements for such models, i.e., computation and storage, are high. As a result, these models are not suitable for resource-constrained devices (for example, IOT). In this work, we highlight the U-Net model, and to deploy it to IOT devices, we compress the same model using a genetic algorithm. We assess the proposed method using a publicly accessible, bench-marked dataset. To verify the efficacy of the suggested methodology, we conducted experiments on two more datasets, specifically CamVid and Potato leaf disease. In addition, we used the suggested method to shrink the MiniSegNet and FCN 32 models, which shows that the compressed U-Net approach works for classifying breast cancer. The results of the study indicate a significant decrease in the storage capacity of UNet with 96.12% compression for the breast cancer dataset with 1.97x enhancement in inference time. However, after compression of the model, there is a drop in accuracy of only 1.33%.</p>","PeriodicalId":7,"journal":{"name":"ACS Applied Polymer Materials","volume":"183 ","pages":"109296"},"PeriodicalIF":4.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142581370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the exposure to <i>Phlebotomus perniciosus</i> and the presence of anti-<i>Leishmania infantum</i> antibodies in stray cats in an endemic region of Spain, and their potential correlation with environmental factors.","authors":"Diana Marteles, María Victoria Martínez, Antonio Fernández, Cristina Riera, Roser Fisa, Xavier Roca-Geronès, Sarah Chavez-Fisa, Sergio Castañeda, Juan David Ramírez, Janine Elizabeth Davis, Petra Sumova, Petr Volf, Maite Verde, Ana González, María Magdalena Alcover, Sergio Villanueva-Saz","doi":"10.1080/01652176.2024.2421308","DOIUrl":"10.1080/01652176.2024.2421308","url":null,"abstract":"<p><p><i>Phlebotomus perniciosus</i> is a major vector of <i>Leishmania infantum</i> in the Mediterranean. While the seroprevalence of leishmaniosis in Spanish dogs and cats has been studied, data on the exposure of cats to <i>P. perniciosus</i> bites under natural conditions without repellents is limited. Stray cats could serve as sentinels for <i>L. infantum</i> and <i>P. perniciosus</i> exposure. This study analyzed sera from 204 apparently healthy stray cats, collected from January 2021 to January 2022, for antibodies against <i>P. perniciosus</i> saliva and <i>L. infantum</i> parasites. Anti-sand fly antibodies were detected in 40.69% of cats using an ELISA with the recombinant salivary protein SP03B of <i>P. perniciosus</i>. Seroprevalence of <i>L. infantum</i> infection was 23.52% by Western blot and 27.41% by ELISA, with an overall seroprevalence of 40.69% (95% CI 34.18-47.54%). This is the first assessment of antibody response to <i>P. perniciosus</i> saliva and <i>L. infantum</i> in naturally exposed stray cats in Spain. Further research is needed to examine the salivary antigens recognized by cats and to explore the relationship between <i>P. perniciosus</i> exposure and <i>L. infantum</i> infection severity in cats.</p>","PeriodicalId":7,"journal":{"name":"ACS Applied Polymer Materials","volume":"44 1","pages":"1-8"},"PeriodicalIF":7.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11544736/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142592146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Growth performance, nutrients digestibility, intestinal microbiota and histology altered in broilers fed maize- or sorghum-based diets.","authors":"Aaqil Ahmad, Asad Sultan, Shabana Naz, Naila Chand, Ziaul Islam, Ibrahim A Alhidary, Rifat Ullah Khan, Samia H Abdelrahman, Sifa Dai","doi":"10.1080/01652176.2024.2373295","DOIUrl":"10.1080/01652176.2024.2373295","url":null,"abstract":"<p><p>This study aimed to evaluate the effect of varying levels of sorghum-based diets as an alternative to maize in broiler nutrition. A total of 320 one-day-old male Ross 708 broiler chickens were randomly allocated to four treatment groups (5 pens per treatment and 16 birds per pen), comprising a control group with a basal diet and groups receiving sorghum-based diets with 20%, 40%, and 100% maize replacement. The overall weight gain was significantly (<i>p</i> < 0.0001) higher in the control group, followed by 20%, 40%, and 100% sorghum replacement. Additionally, overall feed intake was significantly (<i>p</i> < 0.01) higher in the 20% sorghum replacement group compared to the control and other groups. Broilers fed sorghum-based diets exhibited a significantly (<i>p</i> < 0.01) increased feed conversion ratio. Carcass characteristics showed no significant differences between broilers fed corn and sorghum; however, the digestibility of crude protein and apparent metabolizable energy significantly (<i>p</i> < 0.01) increased in the 20% sorghum-corn replacement compared to the 40% and 100% replacement levels. Ileal villus height and width did not differ among the corn-sorghum-based diets, regardless of the replacement percentage. Furthermore, among the cecal microbiota, <i>Lactobacillus</i> count was significantly (<i>p</i> < 0.041) higher in the 20% corn-sorghum diet compared to the 40% and 100% replacement levels. These findings suggest that replacing corn up to 20% of corn with sorghum in broiler diet positively impact growth performance, gut health, nutrient digestibility, and cecal microbiota in broilers. However, larger replacements (40% and 100%) may have negative implications for broiler production and health.</p>","PeriodicalId":7,"journal":{"name":"ACS Applied Polymer Materials","volume":"44 1","pages":"1-8"},"PeriodicalIF":7.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11218579/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141472392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of antimicrobial and non-steroidal anti-inflammatory treatments for BRD on health and welfare in fattening bulls: a cross-sectional study.","authors":"Naod Thomas Masebo, Giovanna Marliani, Flavia Shannon Del Re, Laura Abram, Damiano Cavallini, Marco Di Pietro, Andrea Beltrame, Eliana Schiavon, Marilena Bolcato, Joaquin Hernandez Bermudez, Arcangelo Gentile, Joana G P Jacinto","doi":"10.1080/01652176.2024.2347928","DOIUrl":"10.1080/01652176.2024.2347928","url":null,"abstract":"<p><p>Our study aimed to evaluate the effect of different treatments for BRD on health and welfare in fattening bulls. A total of 264 bulls were enrolled. Welfare was assessed on day 2 (T0) and day 15 (T1) after arrival. A decrease in the welfare level was observed from T0 to T1. All bulls were inspected clinically at T0 and T1 revealing an increase of skin lesions and lameness in T1. In both periods, a high incidence of respiratory disease was observed. A prevalence of 79.55% and 95.45% of <i>Mycoplasma bovis</i> using RT-PCR and culture at T0 and T1 respectively was observed. Blood samples were collected for haematology at T0 and T1. At T0, 36 animals were individually treated for BRD with an antimicrobial (IT), 54 received a metaphylactic treatment with tulathromycin (M), 150 received a metaphylactic treatment with tulathromycin plus a second antimicrobial (M + IT) whereas 24 were considered healthy and therefore not treated (NT). Additionally, 128 were treated with a non-steroid anti-inflammatory (NSAID). Neutrophils of M + IT were significantly higher than groups NT and M and the lymphocytes of M + IT were significantly lower than that of IT. White blood cells, neutrophils and N/L ratio of animals treated with an NSAID was significantly higher than that not treated. Lung inspection of 172 bulls at the abattoir indicated that 92.43% presented at least one lung lesion. A statistically significant effect of the NSAID treatment on the lung lesions was observed. Our findings indicate that BRD was a major welfare and health concern and evidence the difficulties of antimicrobial treatment of <i>M. bovis</i>.</p>","PeriodicalId":7,"journal":{"name":"ACS Applied Polymer Materials","volume":"44 1","pages":"1-11"},"PeriodicalIF":6.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11078067/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140853431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A New Functional Threshold for Minimally Invasive Lobectomy.","authors":"Stijn Vanstraelen, Kay See Tan, Joe Dycoco, Prasad S Adusumilli, Manjit S Bains, Matthew J Bott, Robert J Downey, Katherine D Gray, James Huang, James M Isbell, Daniela Molena, Bernard J Park, Valerie W Rusch, Smita Sihag, David R Jones, Gaetano Rocco","doi":"10.1097/SLA.0000000000006343","DOIUrl":"10.1097/SLA.0000000000006343","url":null,"abstract":"<p><strong>Objective: </strong>To assess the performance of a lower predicted postoperative (ppo) forced expiratory volume in 1 second (FEV 1 ) or diffusion capacity of the lung for carbon monoxide (DLCO) (ppoFEV 1 /ppoDLCO) threshold to predict cardiopulmonary complications after minimally invasive surgery (MIS) lobectomy.</p><p><strong>Background: </strong>Although MIS is associated with better postoperative outcomes than open surgery, MIS uses risk-assessment algorithms developed for open surgery. Moreover, several different definitions of cardiopulmonary complications are used for assessment.</p><p><strong>Methods: </strong>All patients who underwent MIS lobectomy for clinical stage I to II lung cancer from 2018 to 2022 at our institution were considered. The performance of a ppoFEV 1 /ppoDLCO threshold of <45% was compared against that of the current guideline threshold of <60%. Three different definitions of cardiopulmonary complications were compared: Society of Thoracic Surgeons (STS), European Society of Thoracic Surgeons (ESTS), and Berry and colleagues' study.</p><p><strong>Results: </strong>In 946 patients, the ppoFEV 1 /ppoDLCO threshold of <45% was associated with a higher proportion correctly classified [79% (95% CI, 76%-81%) vs 65% (95% CI, 62%-68%); P <0.001]. The complication with the biggest difference in incidence between ppoFEV 1 /ppoDLCO of 45% to 60% and >60% was prolonged air leak [33 (13%) vs 34 (6%); P <0.001]. The predicted probability curves for cardiopulmonary complications were higher for the STS definition than for the ESTS or Berry definitions across ppoFEV 1 and ppoDLCO values.</p><p><strong>Conclusions: </strong>The ppoFEV 1 /ppoDLCO threshold of <45% more accurately classified patients for cardiopulmonary complications after MIS lobectomy, emphasizing the need for updated risk-assessment guidelines for MIS lobectomy to optimize additional cardiopulmonary function evaluation.</p>","PeriodicalId":7,"journal":{"name":"ACS Applied Polymer Materials","volume":" ","pages":"1029-1037"},"PeriodicalIF":7.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140896965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Postoperative Outcomes Among Patients Treated by Male Versus Female Surgeons: A Systematic Review and Meta-analysis.","authors":"Natsumi Saka, Norio Yamamoto, Jun Watanabe, Christopher Wallis, Angela Jerath, Hidehiro Someko, Minoru Hayashi, Kyosuke Kamijo, Takashi Ariie, Toshiki Kuno, Hirotaka Kato, Hodan Mohamud, Ashton Chang, Raj Satkunasivam, Yusuke Tsugawa","doi":"10.1097/SLA.0000000000006339","DOIUrl":"10.1097/SLA.0000000000006339","url":null,"abstract":"<p><strong>Objective: </strong>To compare clinical outcomes of patients treated by female surgeons versus those treated by male surgeons.</p><p><strong>Background: </strong>It remains unclear as to whether surgical performance and outcomes differ between female and male surgeons.</p><p><strong>Methods: </strong>We conducted a meta-analysis to compare patients' clinical outcomes-including patients' postoperative mortality, readmission, and complication rates-between female versus male surgeons. MEDLINE, Embase, CENTRAL, ICTRP, and ClinicalTrials.gov were searched from inception to September 8, 2022. The update search was conducted on July 19, 2023. We used random-effects models to synthesize data and GRADE to evaluate the certainty.</p><p><strong>Results: </strong>A total of 15 retrospective cohort studies provided data on 5,448,121 participants. We found that patients treated by female surgeons experienced a lower postoperative mortality compared with patients treated by male surgeons [8 studies; adjusted odds ratio (aOR), 0.93; 95% CI, 0.88-0.97; I2 =27%; moderate certainty of the evidence]. We found a similar pattern for both elective and nonelective (emergent or urgent) surgeries, although the difference was larger for elective surgeries (test for subgroup difference P =0.003). We found no evidence that female and male surgeons differed for patient readmission (3 studies; aOR, 1.20; 95% CI, 0.83-1.74; I2 =92%; very low certainty of the evidence) or complication rates (8 studies; aOR, 0.94; 95% CI, 0.88-1.01; I2 =38%; very low certainty of the evidence).</p><p><strong>Conclusion: </strong>This systematic review and meta-analysis suggests that patients treated by female surgeons have a lower mortality compared with those treated by male surgeons.</p>","PeriodicalId":7,"journal":{"name":"ACS Applied Polymer Materials","volume":" ","pages":"945-953"},"PeriodicalIF":7.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11542977/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140896967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative toxicity of oral exposure to paraquat: Survival rates and gene expression in two honey bees species; Apis mellifera and Apis cerana.","authors":"Patcharin Phokasem, Terd Disayathanoowat, Thunyarat Chantaphanwattana, Chainarong Sinpoo, Yan Ping Chen, Jay D Evans, Ji-Ho Lee, Sasiprapa Krongdang","doi":"10.1016/j.envpol.2024.125026","DOIUrl":"10.1016/j.envpol.2024.125026","url":null,"abstract":"<p><p>Honey bees provide vital pollination services to agricultural crops and wild plants worldwide. Unfortunately, the misuse and overuse of pesticides in agricultural production have led to an increase in incidents harming honey bees in recent years. Among the commonly utilized bee species in beekeeping are Apis cerana and Apis mellifera, with wild A. cerana populations widely dispersed in forests, contributing substantially to ecosystem balance. Yet, the impact of paraquat, a toxic herbicide, on A. cerana remains largely unexplored. This study aims to address this gap by examining acute exposure endpoints based on mortality represented by median lethal doses (LD₅₀ values) of paraquat, survival rates, and gene expression patterns between the A. cerana and A. mellifera. The findings revealed that A. cerana exhibits greater sensitivity to paraquat compared to A. mellifera. The acute oral LD₅₀ values for A. cerana were 5.85, 1.74, and 1.21 μg/bee at 24, 48, and 72 h, respectively, whereas the corresponding values for A. mellifera were 104.00, 11.00, and 6.41 μg/bee. Further, the study demonstrated significant upregulation of the detoxification (antioxidative) enzymes SOD1, CAT, and LLDH-X2 in both A. mellifera and A. cerana following exposure to the lethal dose of paraquat. However, SOD2 expression was notably downregulated in both species, indicating potential mitochondrial damage. These findings suggest that while honey bees initiate activate defense mechanisms against oxidative damage, paraquat exposure may still impair mitochondrial function. Paraquat was found to be moderately toxic to A. mellifera but highly toxic to A. cerana, indicating the importance of screening multiple bee species when assessing the risks of chemical exposure. This research provides a rare comparative analysis of chemical stress effects on morbidity and gene expression in two different honey bee species, establishing a foundational framework for risk assessment and the regulation of herbicide risks to pollinating insects.</p>","PeriodicalId":7,"journal":{"name":"ACS Applied Polymer Materials","volume":" ","pages":"125026"},"PeriodicalIF":7.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142338073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of new analysis methods for simultaneous and rapid identification of five different microplastics using ATR-FTIR spectroscopy and chemometrics.","authors":"İsmail Tarhan, Hafize Merve Kestek","doi":"10.1016/j.envpol.2024.125043","DOIUrl":"10.1016/j.envpol.2024.125043","url":null,"abstract":"<p><p>Microplastic (MP) pollution in water has become one of the most important global problems of our time. The development of appropriate and rapid analysis techniques is of great importance at the beginning of the studies aimed at solving this problem. In the presented study, in order to perform the qualitative and quantitative analysis of MP forms of polyamide (PA), polyethylene (PE), polypropylene (PP), polystyrene (PS), and polyethylene terephthalate (PET), which are known to be most abundant in water, in a fast and easy way, new Attenuated Total Reflectance-Fourier Transform Infrared (ATR-FTIR) spectroscopy methods were tried to be developed by utilizing chemometric methods. While principal component analysis (PCA) was applied for qualitative analyses, partial least squares (PLS) models were created for quantitative analyses. Raw, 1st, and 2nd order derivatives of all spectra and their spectra with different levels of smoothing points were taken and 24 different chemometric models were created for each MP. In interpreting the statistical performances of the developed PCA and PLS models, different parameters were used. According to the obtained results, the qualitative discrimination of all polymer types was successfully achieved. It was determined that the PLS models developed for the quantitative determination of mixtures consisting of different concentrations of MP types could not be at the desired level. However, it was determined that the PLS models developed for PA, PE, PP, and PET, where the normal spectrum was used, could give quantitatively accurate results, albeit partially.</p>","PeriodicalId":7,"journal":{"name":"ACS Applied Polymer Materials","volume":" ","pages":"125043"},"PeriodicalIF":7.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142338080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}