Science BulletinPub Date : 2025-03-24DOI: 10.1016/j.scib.2025.03.050
Yetang Wang, Petra Heil, Elizabeth R Thomas
{"title":"A network of precipitation observations to improve Antarctic climate and ice sheet projections.","authors":"Yetang Wang, Petra Heil, Elizabeth R Thomas","doi":"10.1016/j.scib.2025.03.050","DOIUrl":"https://doi.org/10.1016/j.scib.2025.03.050","url":null,"abstract":"","PeriodicalId":421,"journal":{"name":"Science Bulletin","volume":" ","pages":""},"PeriodicalIF":18.8,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143770798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intrinsic ion migration-induced susceptible two-dimensional phase-transition memristor with ultralow power consumption.","authors":"Lanhao Qin, Yimeng Yu, Cheng Fang, Yujie Liu, Kaichen Zhu, Decai Ouyang, Shenghong Liu, Bailing Song, Ruochen Zhou, Mario Lanza, Wenhua Hu, Jinsong Wu, Yuan Li, Tianyou Zhai","doi":"10.1016/j.scib.2025.03.051","DOIUrl":"https://doi.org/10.1016/j.scib.2025.03.051","url":null,"abstract":"<p><p>Two-dimensional (2D) phase-transition memristors have demonstrated transformative potential for neuromorphic computing, yet challenges like high power consumption, limited endurance, and crystal damage from external ion intercalation persist. Here, we introduce a novel 2D phase-transition memristor leveraging a paradigm-shifting mechanism by exploiting the ultrafast intrinsic Cu<sup>+</sup> ion migration within Cu<sub>2</sub>S. This approach eliminates the need for external ion insertion, significantly reducing crystal damage and enabling exceptional cycling stability with over 400 DC cycles and 500 pulse cycles. The susceptible monoclinic-tetragonal phase-transition induced by intrinsic Cu<sup>+</sup> migration achieves an unprecedented SET power consumption of 1 μW at 100 mV, significantly lower in currently reported phase-transition memristors. To further demonstrate the potential of intrinsic ion migration-induced (IIM) memristor, we simulated an IIM memristor crossbar array for image preprocessing in gesture recognition with a high SSIM value of 0.94, showcasing its potential for scalable neuromorphic hardware. This work establishes a new paradigm in low-power, high-performance phase-transition memristors, advancing their practical application in next-generation computing.</p>","PeriodicalId":421,"journal":{"name":"Science Bulletin","volume":" ","pages":""},"PeriodicalIF":18.8,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143770820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An automatic annotation tool and reference database for T cell subtypes and states at single-cell resolution.","authors":"Wen-Kang Shen, Chu-Yu Zhang, Yi-Min Gu, Tao Luo, Si-Yi Chen, Tao Yue, Gui-Yan Xie, Yu Liao, Yong Yuan, Qian Lei, An-Yuan Guo","doi":"10.1016/j.scib.2025.02.043","DOIUrl":"https://doi.org/10.1016/j.scib.2025.02.043","url":null,"abstract":"<p><p>T cells have various subtypes and states with different functions. However, a reference list and automated annotation tool for T cell subtypes and states are lacking, which is critical for analyzing and comparing T cells under various conditions. We constructed the largest human T cell reference, containing 1,348,268 T cells from 35 conditions and 16 tissues. We classified T cells into 33 subtypes and further stratified them into 68 categories according to subtype and state. Based on this reference, we developed a tool named STCAT to automatically annotate T cells from scRNA-seq data by hierarchical models and marker correction. The accuracy of STCAT was 28% higher than that of existing tools validated on six independent datasets, including cancer and healthy samples. Using STCAT, we consistently discovered that CD4<sup>+</sup> Th17 cells were enriched in late-stage lung cancer patients in multiple datasets, whereas MAIT cells were prevalent in milder-stage COVID-19 patients. We also confirmed a decrease in Treg cytotoxicity in post-treatment ovarian cancer. Systematic landscape analyses of CD4<sup>+</sup> and CD8<sup>+</sup> T cell references revealed that CD4<sup>+</sup> Treg cells were enriched in tumor samples and that CD8<sup>+</sup> naive-related cells were abundant in healthy individuals. Finally, we deposited all the T cell references and annotations into a TCellAtlas (https://guolab.wchscu.cn/TCellAtlas) database, which allows users to browse T cell expression profiles and analyze customized scRNA-seq data by STCAT. In conclusion, comprehensive human T cell subtypes and states reference, automated annotation tool, and database will greatly facilitate research on T cell immunity and tumor immunology.</p>","PeriodicalId":421,"journal":{"name":"Science Bulletin","volume":" ","pages":""},"PeriodicalIF":18.8,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143741819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bio-inspired thermoelectric cement with interfacial selective immobilization towards self-powered buildings.","authors":"Yulin Wang, Yangzezhi Zheng, Weihuan Li, Shuai Xiao, Shengjun Chen, Jiarui Xing, Chenchen Xiong, Yang Zhou, Wei Zhang, Takehiko Hihara, Nosipho Moloto, Changwen Miao","doi":"10.1016/j.scib.2025.03.032","DOIUrl":"https://doi.org/10.1016/j.scib.2025.03.032","url":null,"abstract":"<p><p>Buildings and infrastructure significantly contribute to global energy consumption and CO<sub>2</sub> emissions. Transforming cement, the most widely used construction material, into a functional medium for heat harvesting presents a promising avenue to offset the energy demands of buildings. The disparity in diffusion rate between cations and anions within cement pore solution due to variations in interactions with pore walls, endows cement with inherent ionic thermoelectric properties. However, the isolation of pores by the dense cement matrix hinders the rapid transportation of ions with superior diffusion rates, impeding the enhancement of mobility difference between ions and limiting the enhancement of Seebeck coefficient. Inspired by the stem structure of plants, we present a cement-polyvinyl alcohol (PVA) composite (CPC) featuring aligned cement and PVA hydrogel layers. While PVA hydrogel layers provide ion diffusion highways for OH<sup>-</sup> ions, cement-PVA interfaces establish strong coordination bonds with Ca<sup>2+</sup> ions and weaker interactions with OH<sup>-</sup> ions, enabling selective immobilization, which amplifies the diffusion rate disparity between Ca<sup>2+</sup> and OH<sup>-</sup>. The CPC's multilayer structure yields abundant interfaces, providing ample interaction sites that maximize the contribution of cement ions to thermoelectric performance. The as-prepared composite achieves an impressive Seebeck coefficient of -40.5 mV/K and a figure of merit (ZT) of 6.6 × 10<sup>-2</sup>. Due to the engineered multilayer structure, the CPC also demonstrates superior mechanical strength and intrinsic energy storage potential, which has been assembled into a self-powered architecture. The biomimetic structure and interfacial selective immobilization mechanism may pave the way for the design and fabrication of high-performance ionic thermoelectric materials.</p>","PeriodicalId":421,"journal":{"name":"Science Bulletin","volume":" ","pages":""},"PeriodicalIF":18.8,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143778658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Science BulletinPub Date : 2025-03-17DOI: 10.1016/j.scib.2024.12.054
Yansui Liu, Cong Ou, Yaqun Liu, Zhi Cao, Guy M Robinson, Xunhuan Li
{"title":"Unequal impacts of global urban-rural settlement construction on cropland and production over the past three decades.","authors":"Yansui Liu, Cong Ou, Yaqun Liu, Zhi Cao, Guy M Robinson, Xunhuan Li","doi":"10.1016/j.scib.2024.12.054","DOIUrl":"https://doi.org/10.1016/j.scib.2024.12.054","url":null,"abstract":"<p><p>The world has experienced a rapid expansion of human settlements in both urban and rural areas in recent decades, yet the unequal impacts of this construction on global food security remain unclear. In this study, we delineated the global-scale expansion of urban-rural settlements at a fine resolution from 1985 to 2020 and quantified their uneven impacts on food security, focusing on the relationships between settlement types, cropland categories, and disparities in crop production. Our results showed that despite dramatic urbanization, rural settlements still constituted the majority of human settlement areas in 2020. Globally, cropland loss due to the expansion of rural settlements was 1.2 times greater than that caused by urbanization, while the associated yield loss was 1.5 times higher. Notably, urban-rural settlement expansion in Asia accounted for 61% of cropland loss and 64% of yield loss. Moreover, future scenarios predicted that Asia's urban-rural settlement expansion will continue to have the most significant impacts on the loss of cropland and yield throughout the 2030s. These results provide systematic evidence of the unequal impacts of urban-rural settlement construction on global cropland and food security.</p>","PeriodicalId":421,"journal":{"name":"Science Bulletin","volume":" ","pages":""},"PeriodicalIF":18.8,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143741909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}