Anais da Academia Brasileira de Ciencias最新文献

Immunological and Hepatic Responses to ChAdOx1-S/nCoV-19 Vaccination in Brazilian Academic Volunteers. 巴西学术志愿者对ChAdOx1-S/nCoV-19疫苗的免疫和肝脏反应

IF 1.2 4区综合性期刊

Anais da Academia Brasileira de Ciencias Pub Date : 2026-08-28 eCollection Date: 2026-01-01 DOI: 10.1590/0001-3765202620251157

Viktória Aparecida G S Coelho, Graziele F DE Sousa, Amanda Cristina V F DA Silva, Flávia B Mury, Cintia M DE Barros

引用次数: 0

How do abiotic stresses influence the seed germination and vigor of tree species from the Pampa biome? 非生物胁迫如何影响潘帕草原生物群系树种的种子萌发和活力？

IF 1.2 4区综合性期刊

Anais da Academia Brasileira de Ciencias Pub Date : 2026-08-28 eCollection Date: 2026-01-01 DOI: 10.1590/0001-3765202620250073

Júlia Luiza Stahl, Jocimar C Milagre, Lucas José Mendes, Max Vinícios R DE Sousa, Jana S Noronha, Regina Pase, Matheus D Gazzola, Suelen C Aimi, Ezequiel Gasparin, Maristela M Araujo

{"title":"How do abiotic stresses influence the seed germination and vigor of tree species from the Pampa biome?","authors":"Júlia Luiza Stahl, Jocimar C Milagre, Lucas José Mendes, Max Vinícios R DE Sousa, Jana S Noronha, Regina Pase, Matheus D Gazzola, Suelen C Aimi, Ezequiel Gasparin, Maristela M Araujo","doi":"10.1590/0001-3765202620250073","DOIUrl":"https://doi.org/10.1590/0001-3765202620250073","url":null,"abstract":"The Pampa biome is increasingly threatened by anthropogenic pressure and climate change, which intensify thermal extremes, water scarcity, and soil salinity, negatively affecting seed production and dispersal. This study evaluated the effects of thermal, water, and salinity stresses on the germination and vigor of Neltuma affinis and Vachellia caven, two ecologically and economically important Fabaceae species native to the Pampa parklands. The seeds were subjected to different temperatures (15, 25, 30, and 35 °C), polyethylene glycol (PEG) concentrations (0.0, -0.41, -0.58, and -0.79 MPa), and NaCl concentrations (0.0, -0.46, -0.92, and -1.37 MPa). Germination of N. affinis was not observed at 15 or 35 °C, whereas V. caven failed to germinate only at 15 °C. Under water stress, both species showed reduced germination and germination speed index (GSI). While V. caven demonstrated tolerance to salinity, N. affinis germination and GSI were inversely proportional to salinity. Overall, V. caven showed tolerance to thermal and saline stress, whereas N. affinis was significantly more sensitive to abiotic stresses. Given the limited distribution of N. affinis in Brazil, together with ongoing anthropogenic pressure and increasing climatic extremes, this species may be at risk of extinction due to reduced germination capacity and seed vigor.","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"98 3","pages":"e20250073"},"PeriodicalIF":1.2,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148886146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Regional Inequalities in Basic Sanitation and Public Health Impacts in Brazil's capitals. 巴西首都基本卫生和公共卫生影响方面的区域不平等。

IF 1.2 4区综合性期刊

Anais da Academia Brasileira de Ciencias Pub Date : 2026-08-28 eCollection Date: 2026-01-01 DOI: 10.1590/0001-3765202620241531

Daniela P Vaiss, Livia S Freitas, Fernanda B DE Miranda, Denise S Brião, Stálin S Damasceno, Gabriella M G V DE Azevedo, Fabiana Finger-Jardim, Flavio Manoel R DA Silva Júnior

{"title":"Regional Inequalities in Basic Sanitation and Public Health Impacts in Brazil's capitals.","authors":"Daniela P Vaiss, Livia S Freitas, Fernanda B DE Miranda, Denise S Brião, Stálin S Damasceno, Gabriella M G V DE Azevedo, Fabiana Finger-Jardim, Flavio Manoel R DA Silva Júnior","doi":"10.1590/0001-3765202620241531","DOIUrl":"https://doi.org/10.1590/0001-3765202620241531","url":null,"abstract":"Regional inequalities in basic sanitation remain a major public health challenge in Brazil. This study assessed the relationship between sanitation indicators and health outcomes related to Diseases Related to Inadequate Environmental Sanitation (DRSAI) in Brazilian capitals from 2010 to 2019. Mortality and hospitalization data were obtained from DATASUS, and water and sewerage coverage indicators from the National Sanitation Information System (SNIS). Pearson correlations and hierarchical cluster analyses were used to explore spatial patterns and associations. Pronounced regional disparities were observed. Northern and Northeastern capitals, including Macapá, Recife, and Salvador, had the highest DRSAI mortality and hospitalization rates, coinciding with the lowest sewerage coverage (<30%) and limited potable water access (<60%). In contrast, Southern and Southeastern capitals, including Curitiba, Porto Alegre, and São Paulo, showed better sanitation and health indicators. Sewage coverage was significantly and negatively correlated with hospitalization and mortality rates (p<0.05), indicating an inverse association between sanitation coverage and DRSAI outcomes. The findings highlight the central role of sanitation in reducing inequalities in DRSAI-related hospitalizations and mortality. Despite progress, universal access remains distant and requires targeted investments and integrated public policies to improve sanitation and public health outcomes in Brazil, particularly in the country's most socially vulnerable urban areas.","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"98 suppl 1","pages":"e20241531"},"PeriodicalIF":1.2,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148886116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Alkaline lignin from Crataeva tapia leaves: in vitro antimicrobial, antibiofilm, cytotoxic evaluation and potential application in pharmaceutical tablets. 山楂叶碱性木质素：体外抗菌、抗生物膜、细胞毒性评价及在片剂中的潜在应用。

IF 1.2 4区综合性期刊

Anais da Academia Brasileira de Ciencias Pub Date : 2026-08-28 eCollection Date: 2026-01-01 DOI: 10.1590/0001-3765202620240855

Lisandra S Lima, Diego S C Marques, Rejane P Neves, Maria Daniela S Buonafina-Paz, Andressa Nathally R Leal, Mary Angela A DE Souza, Maria Carmo A DE Lima, Iranildo José DA Cruz Filho

{"title":"Alkaline lignin from Crataeva tapia leaves: in vitro antimicrobial, antibiofilm, cytotoxic evaluation and potential application in pharmaceutical tablets.","authors":"Lisandra S Lima, Diego S C Marques, Rejane P Neves, Maria Daniela S Buonafina-Paz, Andressa Nathally R Leal, Mary Angela A DE Souza, Maria Carmo A DE Lima, Iranildo José DA Cruz Filho","doi":"10.1590/0001-3765202620240855","DOIUrl":"https://doi.org/10.1590/0001-3765202620240855","url":null,"abstract":"The lignin extracted from the leaves of Crataeva tapia was investigated for its antimicrobial activity and potential use in solid pharmaceutical formulations. The leaves contained 35% cellulose, 23.4% hemicellulose, 17.3% lignin, 19.1% extractives, and 4.7% ash. The extraction yield after acid precipitation was 67.8%. Cytotoxicity assays in RAW 264.7, J774, Vero, V79, and HepG2 cells showed low toxicity (IC50 >1000 µg/mL) and no hemolytic activity (<10%). Lignin exhibited MIC values ranging from 512 to >1024 µg/mL, with no MBC or MFC detected. The best antibacterial result was observed against Staphylococcus aureus UFPEDA-709 (MIC 512 µg/mL), comparable to oxacillin. Among Candida strains, notable results were obtained for HAM11 (128 µg/mL; fluconazole 0.5 µg/mL) and HAM13 (128 µg/mL; fluconazole 4 µg/mL). No synergism was observed against bacteria, but additive and synergistic effects were detected in HAM11 and HAM13, respectively. Lignin reduced HAM13 biofilm formation by 16%. Ergosterol assays suggested its action on fungal cell walls and membranes. Tablets containing lignin showed hardness of 5.5 Kgf/cm², friability of 0.93%, and disintegration in 36.2 min, while those without lignin showed 4.6 Kgf/cm², 0.15%, and 31 min, respectively. These findings highlight C. tapia lignin as a versatile and promising biomaterial for sustainable fluconazole-based formulations and adjuvant therapies.","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"98 suppl 1","pages":"e20240855"},"PeriodicalIF":1.2,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148886077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In Vivo Assessment of Cardiotoxicity Induced by Difenoconazole and Prothioconazole in a Rodent Model. 二苯醚康唑和原硫康唑对啮齿动物模型心脏毒性的体内评价。

IF 1.2 4区综合性期刊

Anais da Academia Brasileira de Ciencias Pub Date : 2026-08-28 eCollection Date: 2026-01-01 DOI: 10.1590/0001-3765202620250754

Jorge Lucas Teixeira-Fonseca, Polyana L DA Silva, Leisiane P Marques, Diego Jose B Orts, Michael Ramon L Conceição, Aline Naomi Ito, Danilo Roman-Campos

{"title":"In Vivo Assessment of Cardiotoxicity Induced by Difenoconazole and Prothioconazole in a Rodent Model.","authors":"Jorge Lucas Teixeira-Fonseca, Polyana L DA Silva, Leisiane P Marques, Diego Jose B Orts, Michael Ramon L Conceição, Aline Naomi Ito, Danilo Roman-Campos","doi":"10.1590/0001-3765202620250754","DOIUrl":"https://doi.org/10.1590/0001-3765202620250754","url":null,"abstract":"The application of triazole fungicides in agriculture has raised concerns regarding their potential deleterious effects on human health. Thus, the present study aimed to evaluate the in vivo cardiotoxicity of fungicides difenoconazole (DFZ) and prothioconazole (PRZ), in Wistar rats subjected to daily administration of 1 mg/kg/day, corresponding to the non-observed adverse effect level (NOAEL), by gavage over a period of 28 consecutive days. No significant alterations were observed in the weights of the heart, right atrium, left atrium, spleen, liver, and lungs of the animals. Histopathological analyses of the myocardium revealed no evidence of cardiac hypertrophy. Electrocardiographic assessments did not indicate significant changes in P wave duration, PR and QT intervals, QRS complex, or RR interval. Furthermore, during the cardiac stress tests induced by caffeine and dobutamine, DFZ and PRZ did not increase the likelihood of developing cardiac arrhythmias, nor did they augment the infarct area as measured by TTC/Evans Blue staining. Also, serum levels of the cardiac biomarkers CK-MB and LDH were comparable to those of the control group. Collectively, these results suggest that DFZ and PRZ, at the administered dose and time frame, do not induce structural or electrical alterations in the hearts of rats.","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"98 suppl 1","pages":"e20250754"},"PeriodicalIF":1.2,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148886112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Modulatory effects of methyl gallate on the inflammatory response in gout arthritis via P2X7 receptor. 没食子酸甲酯通过P2X7受体对痛风关节炎炎症反应的调节作用

IF 1.2 4区综合性期刊

Anais da Academia Brasileira de Ciencias Pub Date : 2026-08-28 eCollection Date: 2026-01-01 DOI: 10.1590/0001-3765202620250722

Felipe M S Pereira, Luana B Correa, Leonardo N Seito, Natalia L VON Ranke, Guilherme Eduardo M Mendes, Murilo L Bello, Luiz Eduardo B Sávio, Robson Coutinho-Silva, Robson X Faria, Maria G Henriques, Elaine C Rosas

引用次数: 0

Limnological parameters, metabarcoding, infrared spectroscopy, and chemometrics for characterizing freshwater cyanobacteria communities. 湖泊参数，元条形码，红外光谱，和化学计量学表征淡水蓝藻群落。

IF 1.2 4区综合性期刊

Anais da Academia Brasileira de Ciencias Pub Date : 2026-08-28 eCollection Date: 2026-01-01 DOI: 10.1590/0001-3765202620250432

Schirley Tostes, Forrest William Lefler, Jéssica Aparecida Moretto, David Erwin Berthold, Haywood Dail Laughinghouse Iv, Alexandre Rieger, Valeriano Antonio Corbellini, Rosana DE C DE S Schneider

{"title":"Limnological parameters, metabarcoding, infrared spectroscopy, and chemometrics for characterizing freshwater cyanobacteria communities.","authors":"Schirley Tostes, Forrest William Lefler, Jéssica Aparecida Moretto, David Erwin Berthold, Haywood Dail Laughinghouse Iv, Alexandre Rieger, Valeriano Antonio Corbellini, Rosana DE C DE S Schneider","doi":"10.1590/0001-3765202620250432","DOIUrl":"https://doi.org/10.1590/0001-3765202620250432","url":null,"abstract":"Harmful cyanobacterial blooms pose risks to the environment, humans, and animals. Rapid identification of these microorganisms is essential but still relies on costly and time-consuming techniques. This study evaluates the potential of attenuated total reflectance infrared spectroscopy (ATR-FTIR) combined with chemometrics, supported by molecular methods, to detect potentially harmful cyanobacteria. Samples were collected from 14 sites in the Rio Pardo Valley, RS, Brazil, with limnological parameters measured. Spectra (4000-650 cm⁻¹) in triplicate, and 16S rRNA metabarcoding was performed using Dada2, Phyloseq, and the CyanoSeq database. PCA and OPLS analyses were applied to integrate spectral, taxonomic, and environmental data. Twelve cyanobacterial genera were identified. Sphaerospermopsis (Zapomelová et al., 2010) dominated SP14, associated with aluminum, iron, and nitrogen levels. Dolichospermum ((Bornet & Flahault) P. Wacklin, L. Hoffmann & Komárek, 2009) and Wollea (Bornet & Flahault, 1886) correlated with phosphorus and sodium. Planktothricoides (S. Suda & M. Watanabe, 2002) showed 95.15% abundance at SP01. PC1×PC2 plots revealed location-based clustering of spectral data. ATR/OPLS models showed strong correlations with relative abundances derived from metabarcoding data, with RMSECV values from 1.3×10⁻⁵ to 5.3×10⁻⁴ and R² > 0.99. These results support ATR-FTIR and chemometrics as a promising exploratory approach for the assessment of cyanobacterial community composition in freshwater systems.","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"98 3","pages":"e20250432"},"PeriodicalIF":1.2,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148886228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the Interplay of Oceanic Tides and Rainfall in Flood Susceptibility in an Exorheic Basin. 探讨海洋潮汐与降水在泛海盆地洪水易感性中的相互作用。

IF 1.2 4区综合性期刊

Anais da Academia Brasileira de Ciencias Pub Date : 2026-08-28 eCollection Date: 2026-01-01 DOI: 10.1590/0001-3765202620250083

Victor Matheus C DE Carvalho, Gabriel N Guimarães, Laura Cristina M Xavier, João Vitor M Bravo

{"title":"Exploring the Interplay of Oceanic Tides and Rainfall in Flood Susceptibility in an Exorheic Basin.","authors":"Victor Matheus C DE Carvalho, Gabriel N Guimarães, Laura Cristina M Xavier, João Vitor M Bravo","doi":"10.1590/0001-3765202620250083","DOIUrl":"https://doi.org/10.1590/0001-3765202620250083","url":null,"abstract":"Floods are among the most harmful natural disasters for humans, and rising global temperatures tend to make them more frequent. This paper aims to model flood susceptibility in Rio de Janeiro, Brazil, based on the 2019 and 2020 floods. The methodology used in the paper is based on the Analytical Hierarchy Process. The contribution of variables to extreme flood events was calculated to assess the influence of oceanic tides in conjunction with the extreme rainfall. The methodological procedures were mainly based on acquiring data referring to rainfall records, ocean tide oscillations, and other natural-anthropogenic variables. The results showed that ocean tidal oscillation in that region has played a secondary but essential role in flood events. Furthermore, observing ocean tide dynamics and extreme rainfall events is the key combination for explaining, preventing, and forecasting extreme flood events. For future research, it is recommended that the improvement of quality data (geodetic and meteorological) is essential to model flood susceptibility in coastal areas.","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"98 suppl 1","pages":"e20250083"},"PeriodicalIF":1.2,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148886084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A new species of Malanea Aubl. (Rubiaceae, Guettardeae) from the Atlantic Forest of Espírito Santo, Brazil. 标题马兰属一新种。（Rubiaceae, guettardae）产自巴西Espírito Santo的大西洋森林。

IF 1.2 4区综合性期刊

Anais da Academia Brasileira de Ciencias Pub Date : 2026-08-28 eCollection Date: 2026-01-01 DOI: 10.1590/0001-3765202620251282

Rafaela S P Roxo, Maria Regina V Barbosa

引用次数: 0

Assessing trace metal concentration in urban soils: a study of urban parks and unforested urban areas. 评估城市土壤中痕量金属浓度：对城市公园和未森林城市地区的研究。

IF 1.2 4区综合性期刊

Anais da Academia Brasileira de Ciencias Pub Date : 2026-08-28 eCollection Date: 2026-01-01 DOI: 10.1590/0001-3765202620250560

Priscila B Penteado, Danilo C Nogarotto, Bruno Elias S Costa, Vanessa N Alves, Bruna Fernanda F Oliveira, Simone A Pozza, Felippe B Canteras

{"title":"Assessing trace metal concentration in urban soils: a study of urban parks and unforested urban areas.","authors":"Priscila B Penteado, Danilo C Nogarotto, Bruno Elias S Costa, Vanessa N Alves, Bruna Fernanda F Oliveira, Simone A Pozza, Felippe B Canteras","doi":"10.1590/0001-3765202620250560","DOIUrl":"https://doi.org/10.1590/0001-3765202620250560","url":null,"abstract":"Urban soils act as long-term reservoirs for trace metals, yet how soil physicochemical properties and anthropogenic pressure interact over time remains poorly understood in medium-sized cities of the Global South. This study evaluates the spatiotemporal dynamics and ecological risks of Ba, Cu, Zn, Pb, Cr, Ni, Mo, Co, and Cd in urban topsoils, through a 33-week monitoring campaign. Linear Mixed Models (LMM) and Positive Matrix Factorization (PMF) were combined to identify retention controls and source contributions. No significant temporal variability was observed (p > 0.05), confirming soil as a stationary reservoir, whereas marked spatial heterogeneity occurred (p < 0.001), driven by localized soil properties. LMM results highlighted soil organic matter (SOM) as a key enhancer of Cu (β = 6.15) and Zn (β = 17.9) retention, while pH exerted a strong negative control on Pb mobility (β = -23.9 x 104). PMF identified three major contributors: geogenic sources (35.9%), industrial/traffic emissions (32.4%), and mixed anthropogenic-lithogenic inputs (30.7%). Although metal concentrations remained below intervention thresholds, localized Cd-driven ecological risks persist in densely populated areas. This study highlights that vegetation and SOM function as vital geochemical sinks for metal immobilization, offering effective pathways for sustainable urban risk mitigation.","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"98 suppl 1","pages":"e20250560"},"PeriodicalIF":1.2,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148886061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0