Analysis of the antimicrobial activity of propolis: A narrative review of in-vitro studies.

IF 1.1 4区 综合性期刊 Q3 MULTIDISCIPLINARY SCIENCES
Anais da Academia Brasileira de Ciencias Pub Date : 2025-06-20 eCollection Date: 2025-01-01 DOI:10.1590/0001-3765202520241302
Glenda L Lazo, Danieli Cristina Lemes, Patrícia M Pauletti, Jairo K Bastos, Sérgio Ricardo Ambrósio, Rodrigo Cassio S Veneziani, Regina Helena Pires
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引用次数: 0

Abstract

Propolis, harvested by bees from local and seasonal flora, exhibits a diverse chemical composition renowned for its antimicrobial, antioxidant, and anti-inflammatory attributes. This positions it as a promising ally in combatting antimicrobial resistance. This narrative review aims to provide a comprehensive investigation of in vitro studies investigating propolis' antimicrobial efficacy. Employing the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) methodology, we conducted searches in PubMed, SciELO, and Lilacs databases. Articles published between 2011 and 2023, in English, Spanish, or Portuguese, and focusing on propolis' in vitro antimicrobial activity against human pathogens were included using descriptors. Out of 291 initially identified articles, 34 were meticulously chosen post-application of exclusion criteria. Despite originating from diverse regions, propolis consistently demonstrates a rich profile abundant in fundamental phenolic compounds and flavonoids. The synergy of its constituent elements' leads to significant antibacterial significant antibacterial and antifungal effects via distinct mechanisms. Appreciating the varied chemical compositions of propolis is imperative for optimizing its therapeutic potential. Its remarkable antibacterial and antifungal attributes, alongside standardized testing methodologies and exploration of synergistic combinations with conventional antibiotics or essential oils, present compelling strategies for effectively addressing antimicrobial resistance.

蜂胶抗菌活性分析:体外研究述评。
蜂胶是由蜜蜂从当地和季节性植物群中收获的,具有多种化学成分,以其抗菌、抗氧化和抗炎特性而闻名。这使它成为抗击抗菌素耐药性的一个有希望的盟友。本文综述了蜂胶抗菌功效的体外研究进展。采用系统评价和荟萃分析首选报告项目(PRISMA)方法,我们在PubMed、SciELO和Lilacs数据库中进行了搜索。2011年至2023年间以英语、西班牙语或葡萄牙语发表的文章,重点关注蜂胶对人类病原体的体外抗菌活性,并使用描述符纳入其中。在最初确定的291项条款中,有34项是在适用排除标准后精心挑选的。尽管蜂胶起源于不同的地区,但蜂胶始终显示出丰富的基本酚类化合物和类黄酮。其组成元素的协同作用通过不同的机制导致显著的抗菌和抗真菌作用。了解蜂胶的不同化学成分是优化其治疗潜力的必要条件。其显著的抗菌和抗真菌特性,以及标准化测试方法和探索与传统抗生素或精油的协同组合,为有效解决抗菌素耐药性提供了令人信服的战略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Anais da Academia Brasileira de Ciencias
Anais da Academia Brasileira de Ciencias 综合性期刊-综合性期刊
CiteScore
2.20
自引率
0.00%
发文量
347
审稿时长
1 months
期刊介绍: The Brazilian Academy of Sciences (BAS) publishes its journal, Annals of the Brazilian Academy of Sciences (AABC, in its Brazilianportuguese acronym ), every 3 months, being the oldest journal in Brazil with conkinuous distribukion, daking back to 1929. This scienkihic journal aims to publish the advances in scienkihic research from both Brazilian and foreigner scienkists, who work in the main research centers in the whole world, always looking for excellence. Essenkially a mulkidisciplinary journal, the AABC cover, with both reviews and original researches, the diverse areas represented in the Academy, such as Biology, Physics, Biomedical Sciences, Chemistry, Agrarian Sciences, Engineering, Mathemakics, Social, Health and Earth Sciences.
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