Anais da Academia Brasileira de Ciencias最新文献_第10页

The intermodal transport tactical planning: A literature review on the use of transportation modes for cargo delivery. 多式联运战术规划：关于使用运输模式运送货物的文献综述。

IF 1.1 4区综合性期刊

Anais da Academia Brasileira de Ciencias Pub Date : 2024-10-28 eCollection Date: 2024-01-01 DOI: 10.1590/0001-3765202420240081

Jonathan Vieira, Alvaro Neuenfeldt Júnior, Vanessa Alves, Marina Bouzon, Matheus Francescatto

{"title":"The intermodal transport tactical planning: A literature review on the use of transportation modes for cargo delivery.","authors":"Jonathan Vieira, Alvaro Neuenfeldt Júnior, Vanessa Alves, Marina Bouzon, Matheus Francescatto","doi":"10.1590/0001-3765202420240081","DOIUrl":"10.1590/0001-3765202420240081","url":null,"abstract":"Effective freight transportation planning through different modes drives countries economic growth by ensuring the delivery of goods safely and sustainably. This article provides a systematic literature review focused on intermodal transport tactical planning, addressing logistical technical factors for efficient transportation modes management in cargo delivery. The methodology is based on the research questions definition, search process, and article selection criteria, exploring the network structures evolution to verify technical factors influencing network structures, including mode combinations, geographical distribution, and mathematical models' decision variables and constraints. According to the research question proposed, the most relevant technical factors for intermodal planning network structures are flow cargo, transport modal activation, flow conservation, delivery time, and vehicle management, generally found in countries with extensive road infrastructure and a high modal integration capacity, as China, Europe, and USA. Considering the decision variables and constraints, flow conservation is a common element observed in intermodal transport mathematical models. Thus, a balance between transportation costs and transportation modes utilization was verified, and insights into the relation between technical logistics factors application and network structures for cargo delivery efficiency were revealed. Finally, the systematic literature review contributes to understanding the main intermodal transportation planning evolving landscape, offering valuable insights for future research and practical implementations.","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"96 4","pages":"e20240081"},"PeriodicalIF":1.1,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142543198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recovery of chemical components from Spondias mombin L. leaves using pressurized hot water, ultrasound and turbo-extraction techniques. 利用加压热水、超声波和涡轮萃取技术从Spondias mombin L.叶片中提取化学成分。

IF 1.1 4区综合性期刊

Anais da Academia Brasileira de Ciencias Pub Date : 2024-10-25 eCollection Date: 2024-01-01 DOI: 10.1590/0001-3765202420240177

Victor DE S Pereira, Diego Márlon Ferro, Janaína Carla B Machado, Magda Rhayanny A Ferreira, Luiz Alberto L Soares, Luiz Stragevitch, Leandro Danielski

{"title":"Recovery of chemical components from Spondias mombin L. leaves using pressurized hot water, ultrasound and turbo-extraction techniques.","authors":"Victor DE S Pereira, Diego Márlon Ferro, Janaína Carla B Machado, Magda Rhayanny A Ferreira, Luiz Alberto L Soares, Luiz Stragevitch, Leandro Danielski","doi":"10.1590/0001-3765202420240177","DOIUrl":"https://doi.org/10.1590/0001-3765202420240177","url":null,"abstract":"The fruit of Spondias mombin (cajazeira) is widely consumed in the northeast region of Brazil. In this work, three different extraction methods, namely ultrasound-assisted extraction (UAE), turbo-extraction (TE) and pressurized hot water extraction (PHWE), were evaluated in order to investigate the potential of cajazeira leaves as an alternative source of bioactive compounds. The extraction methods were compared in terms of yield, chemical composition and total phenolic content (TPC) of the extracts. The highest yields and TPC values were obtained by TE with a mixture ethanol: water (70:30%, v/v) as the solvent. PHWE has not yet been applied for the extraction of cajazeira leaves. Thus, it was evaluated as one alternative for the recovery of phenolic compounds under conditions of 80, 100 and 120 °C and 100 and 120 bar. A modeling study of PHWE kinetics was investigated at 80 °C and 200 bar. Furthermore, a biorefinery approach considering integrated processes to recover bioactive compounds was investigated and the results showed that combining processes may enhance the valorization of agricultural waste.","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"96 4","pages":"e20240177"},"PeriodicalIF":1.1,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142543197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Citizen complaints in local media as source of mosquito data: the case of Aedes albifasciatus in an intermediate city of temperate Argentina. 作为蚊虫数据来源的当地媒体上的市民投诉：阿根廷温带中等城市白纹伊蚊的案例。

IF 1.1 4区综合性期刊

Anais da Academia Brasileira de Ciencias Pub Date : 2024-10-25 eCollection Date: 2024-01-01 DOI: 10.1590/0001-3765202420240477

María Alejandra Gallego, María Verónica Simoy, Darío Vezzani

{"title":"Citizen complaints in local media as source of mosquito data: the case of Aedes albifasciatus in an intermediate city of temperate Argentina.","authors":"María Alejandra Gallego, María Verónica Simoy, Darío Vezzani","doi":"10.1590/0001-3765202420240477","DOIUrl":"https://doi.org/10.1590/0001-3765202420240477","url":null,"abstract":"Floodwater mosquitoes provoke nuisance due to their mass emergence. Citizen complaints about outstanding events of mosquitoes in urban areas are usually reflected in local media and could be potentially used as data. Our objective was to build a temperature dependent function to characterize the immature development time of the floodwater mosquito Ae. albifasciatus in Tandil (Argentina), and validate it using citizen complaints in local media and field collected mosquitoes. The development time obtained ranges from 5-47 days at 30-7°C, respectively. During 2000-2021, nine mosquito abundance peaks were identified through local journalistic records. For these events, the estimated hatching date was successfully associated with a previous precipitation, with a maximum difference of two days. The precipitation identified as the trigger for egg hatching ranged from 15 to 121 mm. Then, to associate mosquito news with the target species, female mosquitoes were captured by a battery-powered aspirator in green areas of the city during September 2019-June 2021. Six mosquito abundance peaks were detected in which Ae. albifasciatus accounted for 97.3% of the captures. Among them, journalistic records were able to detect the largest two; i.e. in our study above 15 mosquitoes in a five minute collection. Citizen complaints related to nuisance or vector species could be valuable retrospective data for researchers of different fields.","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"96 4","pages":"e20240477"},"PeriodicalIF":1.1,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142543182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment with thyroid hormones and grape juice in a model of pulmonary hypertension: the response of apoptosis and inflammation. 在肺动脉高压模型中使用甲状腺激素和葡萄汁治疗：细胞凋亡和炎症的反应。

IF 1.1 4区综合性期刊

Anais da Academia Brasileira de Ciencias Pub Date : 2024-10-25 eCollection Date: 2024-01-01 DOI: 10.1590/0001-3765202420240338

Isabel Cristina T Proença, Patrick Türck, Vanessa D Ortiz, Cristina C Proença, Adriane Belló-Klein, Alexandre L DE Castro, Caroline Dani, Alex Sander R Araujo

{"title":"Treatment with thyroid hormones and grape juice in a model of pulmonary hypertension: the response of apoptosis and inflammation.","authors":"Isabel Cristina T Proença, Patrick Türck, Vanessa D Ortiz, Cristina C Proença, Adriane Belló-Klein, Alexandre L DE Castro, Caroline Dani, Alex Sander R Araujo","doi":"10.1590/0001-3765202420240338","DOIUrl":"https://doi.org/10.1590/0001-3765202420240338","url":null,"abstract":"This study explored the association of cardioprotective role of thyroid hormones (TH) and benefit effects of grape juice (GJ) on vascular function against the apoptosis and inflammation associated with monocrotaline (MCT)-induced pulmonary hypertension (PH). Wistar rats were distributed into five groups: control; PH (MCT 60mg/kg i.p.); PH+GJ (GJ-7 µL/g / day, gavage for 14 days); PH+TH (T3, 2μg/100g/day, and T4, 8μg/100g/day, by gavage for 14 days); and PH+TH+GJ. Echocardiographic, morphometric measurements and expression of proteins associated with apoptosis and inflammation were evaluated. The reduced cardiac output (35%) in PH was attenuated in the PH+GJ, PH+TH, and PH+TH+GJ groups (P<0.05). Both GJ and TH had no effect on the PH-induced hypertrophy index. The PH + TH group showed reduced BAX (~90%) and increased Bcl2 levels (~80%) as compared to PH group (P<0.05). The PH-induced increase in caspase 3 was diminished (~92%) in the PH+TH (P<0.05). Both GJ and TH, isolated and combined, reduced caspase 9 levels (~70%). PH-provoked elevated NLRP3 levels was decreased (~90%) in PH+TH (P<0.05). The therapeutic approach showed cardioprotective effects in the PH model which may be mediated by mitigation of apoptosis and inflammation.","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"96 4","pages":"e20240338"},"PeriodicalIF":1.1,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142543199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Consent for organ donation: a case study in the light of bioethics. 同意器官捐赠：从生命伦理学角度进行的个案研究。

IF 1.1 4区综合性期刊

Anais da Academia Brasileira de Ciencias Pub Date : 2024-10-25 eCollection Date: 2024-01-01 DOI: 10.1590/0001-3765202420240126

Kelly C B Gomes, Mary R G Esperandio, José E DE Siqueira, José R Goldim

{"title":"Consent for organ donation: a case study in the light of bioethics.","authors":"Kelly C B Gomes, Mary R G Esperandio, José E DE Siqueira, José R Goldim","doi":"10.1590/0001-3765202420240126","DOIUrl":"https://doi.org/10.1590/0001-3765202420240126","url":null,"abstract":"Fewer donations are being made in Brazil to meet the growing organ demand. Organ donation in Brazil reached an average of 53% consent. However, hospitals in Paraná have reached a level of 94.2%. What reasons could be given for these levels? Accordingly, this study aimed to understand the causes involved in decision-making to donate organs. The methodology used was qualitative based on a case study. Data was collected at a hospital in Toledo, a city in Paraná, through documentary research and semi-structured interviews with two distinct groups: professionals responsible for the family approach to donation and five families consenting to donation. The search for data was restricted to the period between 2015 and 2023. Data analysis used Bardin's content analysis. The results were organized into four categories in the first group, and two categories in the second group, suggesting that aspects linked to bioethical references present in the interview, such as beneficence and autonomy, contribute to the emergence of high rates of family consent for organ donation in the hospital studied. It is recommended for future research to test successful interview models to reverse the current organ donation rates in Brazil.","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"96 4","pages":"e20240126"},"PeriodicalIF":1.1,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142543183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Land use and occupation and pesticide contamination assessment in honey from Africanized honey bees (Hymenoptera: Apidae) using gas chromatography-mass spectrometry. 利用气相色谱-质谱法评估非洲蜜蜂（膜翅目：鳞翅目）蜂蜜中的土地利用和占用情况以及农药污染情况。

IF 1.1 4区综合性期刊

Anais da Academia Brasileira de Ciencias Pub Date : 2024-10-25 eCollection Date: 2024-01-01 DOI: 10.1590/0001-3765202420230547

Fernando DA Cunha, Emerson D Chambó, Silvia Renata M Coelho, Simone Cristina Camargo, Dráuzio C Gama, Regina C Garcia

{"title":"Land use and occupation and pesticide contamination assessment in honey from Africanized honey bees (Hymenoptera: Apidae) using gas chromatography-mass spectrometry.","authors":"Fernando DA Cunha, Emerson D Chambó, Silvia Renata M Coelho, Simone Cristina Camargo, Dráuzio C Gama, Regina C Garcia","doi":"10.1590/0001-3765202420230547","DOIUrl":"https://doi.org/10.1590/0001-3765202420230547","url":null,"abstract":"We examined pesticide contamination in honey from Africanized honey bees in two different seasons, and evaluated the concentration and incidence of these compounds in georeferenced apiaries to provide relevant information for food safety and environmental quality. The land use and occupation of the region were evaluated by selecting 15 apiaries and georeferencing three randomly selected colonies of Africanized honey bees within each apiary. Honey samples were collected during two seasons, and three organochlorine pesticides (p.p`-DDE, Mitotane and Bicyclo[2.2.1]) and four organophosphate pesticides (Ethoprophos, Methyl Parathion, Chlorpyrifos and Fenchlorphos) were analyzed in the honey using gas chromatography-mass spectrometry. 80% of the apiaries showed a predominance of agricultural land use in the foraging areas of the bees. There was a higher concentration of pesticides in samples collected during Season I compared to Season II. There were differences in the proportion of samples contaminated with pesticides between seasons. Some honey samples showed concentrations of the chlorpyrifos pesticide above the levels recommended by Brazilian legislation. Pesticide contamination of honey is not limited to specific application season, indicating the persistent presence and easy availability of pesticides, including banned pesticides not sold or prescribed by agronomists, potentially smuggled from neighboring countries.","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"96 4","pages":"e20230547"},"PeriodicalIF":1.1,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142543195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Barnadesieae, Gochnatieae, Mutisieae and Nassauvieae (Asteraceae) in the Atlantic Forest of Caparaó National Park, Brazil. 巴西卡帕拉奥国家公园大西洋森林中的 Barnadesieae、Gochnatieae、Mutisieae 和 Nassauvieae（菊科）。

IF 1.1 4区综合性期刊

Anais da Academia Brasileira de Ciencias Pub Date : 2024-10-21 eCollection Date: 2024-01-01 DOI: 10.1590/0001-3765202420231065

Polla Renon, Marcelo Monge, Jimi N Nakajima

{"title":"Barnadesieae, Gochnatieae, Mutisieae and Nassauvieae (Asteraceae) in the Atlantic Forest of Caparaó National Park, Brazil.","authors":"Polla Renon, Marcelo Monge, Jimi N Nakajima","doi":"10.1590/0001-3765202420231065","DOIUrl":"https://doi.org/10.1590/0001-3765202420231065","url":null,"abstract":"Asteraceae is highly diverse in the Atlantic Forest, especially in montane environments. The early-diverging tribes within Asteraceae are of particular interest because of their great representation in Brazil and unique features within the family. Thus, a floristic inventory and systematic treatment of these basal grade in Caparaó National Park, an important remnant of Atlantic Forest that has been highlighted for its diversity and endemism, were undertaken. The study was conducted by examining specimens from representative collections of Caparaó and a field expedition. A total of 15 species were found, representing six genera and four tribes, with Mutisieae and Nassauvieae being the most representatives. Six of the species have restricted distributions, either to Brazil (3 spp.), the Atlantic Forest (2) or Caparaó mountain (Mutisia lutzii). Three new records were documented for the park, namely Chaptalia integerrima, Moquiniastrum polymorphum and Mutisia coccinea. Floristic inventories and systematic treatments can make great contributions to science by bringing a better understanding our biodiversity and providing relevant information about flora for the conservation of priority areas.","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"96 4","pages":"e20231065"},"PeriodicalIF":1.1,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142493121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Short-Term Wind Power Interval Forecasting Based on Hybrid Modal Decomposition and Improved Optimization. 基于混合模态分解和改进优化的短期风电间隔预测

IF 1.1 4区综合性期刊

Anais da Academia Brasileira de Ciencias Pub Date : 2024-10-21 eCollection Date: 2024-01-01 DOI: 10.1590/0001-3765202420230891

Jixuan Wang, Yifan Tang, Zengfu Xi, Yujing Wen, Kegui Wu, Yichao Li

{"title":"Short-Term Wind Power Interval Forecasting Based on Hybrid Modal Decomposition and Improved Optimization.","authors":"Jixuan Wang, Yifan Tang, Zengfu Xi, Yujing Wen, Kegui Wu, Yichao Li","doi":"10.1590/0001-3765202420230891","DOIUrl":"https://doi.org/10.1590/0001-3765202420230891","url":null,"abstract":"Accurate wind power prediction can effectively alleviate the pressure of the power system peak frequency regulation, and is more conducive to the economic dispatch of the power system. To enhance wind power forecasting accuracy, a hybrid approach for wind power interval prediction is proposes in this study. Firstly, an Improved Complete Ensemble Empirical Mode Decomposition with Adaptive Noise (ICEEMDAN) is applied to decompose the initial wind power sequence into multiple modes, and Variational Mode Decomposition is used to further decompose the high-frequency non-stationary components. Next, Fuzzy Entropy (FE) is utilized to assess the complexity of the post-decomposed Intrinsic Mode Functions (IMFs), and different forecasting methods are employed accordingly, the point predictions were obtained by linearly summing the component predictions.Additionally, an improved sparrow search algorithm (ISSA) is used to seek the optimal hyperparameters of the prediction algorithm. Finally, the prediction intervals are constructed using the point prediction results based on kernel density estimation (KDE). The root mean square errors (RMSE) of deterministic predictions are 2.8458 MW and 1.8605 MW, with uncertainty coverage rates of 95.83% and 97.92% at a 95% confidence level.","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"96 4","pages":"e20230891"},"PeriodicalIF":1.1,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142493124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Methods to protein and peptide extraction from microalgae: a systematic review. 从微藻中提取蛋白质和肽的方法：系统综述。

IF 1.1 4区综合性期刊

Anais da Academia Brasileira de Ciencias Pub Date : 2024-10-21 eCollection Date: 2024-01-01 DOI: 10.1590/0001-3765202420240113

Ariadne Tennyle V DE Souza, Karoline Mirella S DE Souza, Andreza P DE Amorim, Raquel P Bezerra, Ana Lucia F Porto

{"title":"Methods to protein and peptide extraction from microalgae: a systematic review.","authors":"Ariadne Tennyle V DE Souza, Karoline Mirella S DE Souza, Andreza P DE Amorim, Raquel P Bezerra, Ana Lucia F Porto","doi":"10.1590/0001-3765202420240113","DOIUrl":"https://doi.org/10.1590/0001-3765202420240113","url":null,"abstract":"Currently, there is a demand for protein sources that do not use soil management or animal breeding. Among these sources we highlight the microorganisms, such cyanobacteria and microalgae, which have a simple growth using light, CO2, water and some mineral salts to generate high protein production. The extraction of these proteins depends on the method used. The most used methods for extracting bio-functional proteins are mechanical, chemical and enzymatic. The aim of this work is to analyze the protein extraction methods in microalgae using Scielo, ScienceDirect and NCBI (PubMed) electronic databases that made it possible to select original studies published in the last five years (2018-2023). A total of 2707 articles, 25 of which were selected for further analysis and subjected to risk of bias assessment. The genera Chlorella, Scenedesmus and Nannochloropsis were the most studied due to their high protein content. Mechanical methods and chemical hydrolysis are the most used methods, achieving an extraction yield of 46.0 % and 64.0 %, respectively. The best extraction results are obtained with a combination of methods, reaching up to 80.0 % yield. However, some aspects need to be observed to choose an ideal protein extraction method.","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"96 4","pages":"e20240113"},"PeriodicalIF":1.1,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142493123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Melatonin Administration on Nerve Regeneration after Recurrent Laryngeal Nerve Injury. 褪黑素对复发性喉神经损伤后神经再生的影响

IF 1.1 4区综合性期刊

Anais da Academia Brasileira de Ciencias Pub Date : 2024-10-21 eCollection Date: 2024-01-01 DOI: 10.1590/0001-3765202420231149

Bilgehan Celik, Ahmet Kara, Mehmet Guven, Songül Doganay, Özcan Budak, Ebru M Guven, Tuncay Colak, Ahmet F Erdem, Mahmut S Yilmaz

{"title":"Effect of Melatonin Administration on Nerve Regeneration after Recurrent Laryngeal Nerve Injury.","authors":"Bilgehan Celik, Ahmet Kara, Mehmet Guven, Songül Doganay, Özcan Budak, Ebru M Guven, Tuncay Colak, Ahmet F Erdem, Mahmut S Yilmaz","doi":"10.1590/0001-3765202420231149","DOIUrl":"https://doi.org/10.1590/0001-3765202420231149","url":null,"abstract":"Recurrent Laryngeal Nerve (RLN) injury is a complication in neck surgery. The aim of this study is to evaluate the effect of primary suture repair with melatonin treatment on nerve regeneration after RLN damage. After the RLN damage, nerve repair was performed in the first and fourth groups. The third and fourth groups were given intraperitoneal melatonin therapy daily for six weeks. EMG was applied to all subjects and vocal cord movements were evaluated endoscopically. At the end of the sixth week, all subjects were sacrificed, and their larynx were examinedhistologically. Vocal cord paralysis (VCP) was observed in all subjects after RLN damage. In the sixth week, improvement was observed in the first and fourth group who underwent nerve repair, whereas none in the second and third group, who did not undergo nerve repair, improved. With EMG, the highest MUP was in the fourth group. Histologically, an increase in Schwann cells, a decrease in axon damage, and cytoplasmic vacuolization were in the fourth group. Myelin protein zero and Ki-67 staining were the most in the fourth group. In our study, laryngoscopic, electrophysiological and histopathological findings show that melatonin contributes to nerve healing but this could not translate into functional recovery.","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"96 4","pages":"e20231149"},"PeriodicalIF":1.1,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142493122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0