Anais da Academia Brasileira de Ciencias最新文献

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Lectin-carbohydrate analysis by molecular dynamics: Parkia lectins case study. 分子动力学分析凝集素-碳水化合物:Parkia凝集素案例研究。
IF 1.1 4区 综合性期刊
Anais da Academia Brasileira de Ciencias Pub Date : 2024-12-13 eCollection Date: 2024-01-01 DOI: 10.1590/0001-3765202420230677
Kyria S Nascimento, Vinicius J S Osterne, Messias V Oliveira, Jorge L C Domingos, Wandemberg P Ferreira, Els J M VAN Damme, Benildo S Cavada, Vanir R Pinto-Junior
{"title":"Lectin-carbohydrate analysis by molecular dynamics: Parkia lectins case study.","authors":"Kyria S Nascimento, Vinicius J S Osterne, Messias V Oliveira, Jorge L C Domingos, Wandemberg P Ferreira, Els J M VAN Damme, Benildo S Cavada, Vanir R Pinto-Junior","doi":"10.1590/0001-3765202420230677","DOIUrl":"https://doi.org/10.1590/0001-3765202420230677","url":null,"abstract":"<p><p>Understanding lectin-carbohydrate interactions at the structural and molecular levels is crucial to the field of lectins, as the diverse roles and biological activities exhibited by these proteins are fundamentally linked to their specific binding to target glycoconjugates. This study aimed to apply molecular dynamics to analyze the structure and binding properties of Parkia lectins. 3D structures of Parkia platycephala and P. biglobosa lectins, both unliganded and in complex with D-mannose, were used as inputs for simulations. The trajectories data enabled the study of stability, carbohydrate-binding interactions, and intermonomeric contacts for both proteins. The results revealed stable binding of D-mannose within the lectin domains and their binding mode at each of the three domains, displaying consistent binding motifs across the sites, with slight variations between the lectins and other Jacalin-related lectins. Despite these variations, the binding energies of the lectins with the ligand, as estimated using MM/GBSA, demonstrated favorable interactions in all cases. The dimeric interfaces of both lectins could be identified, and the main contacts have been mapped. These findings enhance our understanding of lectin-carbohydrate interactions and provide insights into the structural properties of Parkia lectins for potential biological and therapeutic applications.</p>","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"96 suppl 3","pages":"e20230677"},"PeriodicalIF":1.1,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142852208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes and collapse in lacustrine system in Antarctic Peninsula ice-free area: Boeckella and Buenos Aires lakes. 南极半岛无冰区湖泊系统的变化和崩塌:Boeckella和Buenos Aires湖泊。
IF 1.1 4区 综合性期刊
Anais da Academia Brasileira de Ciencias Pub Date : 2024-12-13 eCollection Date: 2024-01-01 DOI: 10.1590/0001-3765202420240578
Rosemary Vieira, Priscila Cardoso, Kátia K DA Rosa, Carina Petsch, Juan Manuel Lirio
{"title":"Changes and collapse in lacustrine system in Antarctic Peninsula ice-free area: Boeckella and Buenos Aires lakes.","authors":"Rosemary Vieira, Priscila Cardoso, Kátia K DA Rosa, Carina Petsch, Juan Manuel Lirio","doi":"10.1590/0001-3765202420240578","DOIUrl":"https://doi.org/10.1590/0001-3765202420240578","url":null,"abstract":"<p><p>Some Antarctic ice-free areas have been affected by changes in lacustrine zones and permafrost thawing due to rising air temperatures over the last 60 years Temperature time-series were analyzed to understand the processes leading to the changes of Boeckella and Buenos Aires lakes, north Antarctic Peninsula. Statistical calculations were applied to average, maximum, and minimum temperatures, as well as to indexes such as Positive Degrees Day, Freezing/Thaw Day, and days with temperatures ≥ 0 °C and ≥ 10 °C. Changes in the region over recent decades were observed in mean and maximum temperatures and an increase in minimum temperature since the mid-1990s. In addition, the Normalized Difference Water Index was extracted from Landsat images from 2003, 2016, 2020, and 2021. These images were used to calculate changes in the areas of Boeckella and Buenos Aires lakes. These data revealed an 87% decrease in the area (m²) of Boeckella Lake and a 60% increase in Buenos Aires Lake´s area (m²). Concern has been raised about the modifying lake areas in the Antarctic Peninsula, where the collapse of Boeckella Lake could be the first case recorded in ice-free areas of Antarctica continent.</p>","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"96 suppl 2","pages":"e20240578"},"PeriodicalIF":1.1,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142852071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retreat of Greenwich, Livingston, Robert and Snow Islands glaciers, Antarctica, between 1956 and 2023. 1956年至2023年间,南极洲的格林尼治、利文斯顿、罗伯特和雪岛冰川的撤退。
IF 1.1 4区 综合性期刊
Anais da Academia Brasileira de Ciencias Pub Date : 2024-12-09 eCollection Date: 2024-01-01 DOI: 10.1590/0001-3765202420240555
Danielle D Soffiatti, Kátia K Rosa, Júlia L Lorenz, Filipe Lindau, Carina Petsch, Francisco E Aquino, Jefferson C Simões
{"title":"Retreat of Greenwich, Livingston, Robert and Snow Islands glaciers, Antarctica, between 1956 and 2023.","authors":"Danielle D Soffiatti, Kátia K Rosa, Júlia L Lorenz, Filipe Lindau, Carina Petsch, Francisco E Aquino, Jefferson C Simões","doi":"10.1590/0001-3765202420240555","DOIUrl":"https://doi.org/10.1590/0001-3765202420240555","url":null,"abstract":"<p><p>Glaciers are sensitive to environmental climatic conditions and show their variability over time. This study investigates the environmental characteristics and variation in glacial cover of the Greenwich, Livingston, Robert and Snow islands, Antarctica, between 1956 and 2023. The glacier extension mapping was based on visual interpretation of the Landsat 4, 7 and 8 optical images and normalised difference indexes combination. The REMA 8 digital elevation model was applied to the islands' geomorphometric analysis. Results were compared to climatic series and environmental characteristics. The glacial coverage decreased by 16.9% from 1956 to 2023, equivalent to 209.95 ± 0.113 km². Snow Island, with shallow bathymetry near glacial margins and land-terminating ice-fronts, exhibited the smallest retreat rate values. The glacial coverage of Livingston Island decreased significantly (18%, equivalent to 153.2 ± 0.113 km²) from 1956-2021, representing the highest values in the study. The changes in glacial coverage of the Robert and Greenwich islands were more substantial in the 1989-2023 period than in 1956-1989. Sectors with marine-terminating glaciers, associated with high bathymetric amplitudes, exhibited more significant variations compared to other sectors, contributing to the evolution of fjord-type bays. Glacial coverage has been lost in recent decades due to regional atmospheric and oceanic warming.</p>","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"96 suppl 2","pages":"e20240555"},"PeriodicalIF":1.1,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142811858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Short-term high-fat diet alters behavior, peripheral metabolism, and brain mitochondrial function in Swiss mice. 短期高脂肪饮食改变瑞士小鼠的行为、外周代谢和脑线粒体功能。
IF 1.1 4区 综合性期刊
Anais da Academia Brasileira de Ciencias Pub Date : 2024-12-09 eCollection Date: 2024-01-01 DOI: 10.1590/0001-3765202420240880
Adriano Emanuel Machado, Peterson Rezer, Gianni Mancini, Alexandra Latini, Eduardo Luiz G Moreira
{"title":"Short-term high-fat diet alters behavior, peripheral metabolism, and brain mitochondrial function in Swiss mice.","authors":"Adriano Emanuel Machado, Peterson Rezer, Gianni Mancini, Alexandra Latini, Eduardo Luiz G Moreira","doi":"10.1590/0001-3765202420240880","DOIUrl":"10.1590/0001-3765202420240880","url":null,"abstract":"<p><p>Understanding the temporal dynamics of high-fat diets (HFD) effects on behavior and metabolism is crucial for comprehending their negative impact on organisms. This study investigated the short-term effects (15, 25, and 35 days) of HFD in Swiss mice. Our findings revealed distinct behavioral and metabolic changes throughout the treatment. After 15 days of HFD, mice exhibited impaired exploratory habituation and significant increases in visceral adipose mass, fasting glucose levels, and glucose intolerance. Extending the diet to 25 days intensified the metabolic effects, resulting in compromised acquisition of recognition memory, increased body mass gain, and elevated plasma total cholesterol and triglyceride levels. After 35 days of HFD, these effects were further intensified and accompanied by anxiogenic-like responses in the open field test. Additionally, we observed a positive correlation between metabolic changes and behavioral impairments alongside prefrontal cortex mitochondrial dysfunction. In conclusion, our study reveals the temporal dynamics of behavioral and metabolic changes induced by short-term HFD in Swiss mice, highlighting the relationship between metabolic dysfunction and behavioral impairments. These findings pave the way for future research to unravel the underlying mechanisms and develop strategies to counteract the detrimental effects of HFD on behavior and metabolism.</p>","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"96 suppl 3","pages":"e20240880"},"PeriodicalIF":1.1,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142811923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Drivers and fluxes of dissolved organic carbon along the northern Antarctic Peninsula during late summer. 夏末南极半岛北部溶解有机碳的驱动因素和通量。
IF 1.1 4区 综合性期刊
Anais da Academia Brasileira de Ciencias Pub Date : 2024-12-09 eCollection Date: 2024-01-01 DOI: 10.1590/0001-3765202420240573
Raquel Avelina, Leticia C DA Cunha, Rodrigo Kerr, Cássia O Farias, Claudia Hamacher, Mauricio M Mata
{"title":"Drivers and fluxes of dissolved organic carbon along the northern Antarctic Peninsula during late summer.","authors":"Raquel Avelina, Leticia C DA Cunha, Rodrigo Kerr, Cássia O Farias, Claudia Hamacher, Mauricio M Mata","doi":"10.1590/0001-3765202420240573","DOIUrl":"https://doi.org/10.1590/0001-3765202420240573","url":null,"abstract":"<p><p>Dissolved organic carbon (DOC) is a key component of the biogeochemical carbon cycle in the Southern Ocean. However, there are still significant gaps in understanding the role of DOC in polar environments, due to the limitations of spatiotemporal sampling. In this study, we investigated the regional aspects controlling the distribution and diffusive and advective fluxes of DOC along the northern Antarctic Peninsula (NAP) during austral late summers of 1995 and between 2015 and 2019. DOC concentrations ranged from 33.1 to 157.6 μmol kg-1. The NAP showed regional differences in both its hydrographic conditions and DOC distribution. The regional variability reflected the main biogeochemical sources and fates of DOC associated with the Antarctic Circumpolar Current inflows, the Weddell Gyre transport and the meltwater input. The intensity of the advective fluxes of DOC was 106 times greater than the diffusive fluxes. However, ocean fronts along NAP environments are mesoscale structures for observations of downward and upward diffusive fluxes of DOC. This study adds insights on the role of DOC as a proxy for a better understanding of the coupling between physical and biogeochemical processes over time in an environment sensitive to climate change.</p>","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"96 suppl 2","pages":"e20240573"},"PeriodicalIF":1.1,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142811740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Valorization of agro-industrial wastes of sugarcane bagasse and rice husk for biosorption of Yellow Tartrazine dye. 蔗渣、稻壳等工农业废弃物生物吸附柠檬黄染料的研究。
IF 1.1 4区 综合性期刊
Anais da Academia Brasileira de Ciencias Pub Date : 2024-12-09 eCollection Date: 2024-01-01 DOI: 10.1590/0001-3765202420231308
Débora H Micheletti, João Gabriel S Andrade, Carlos Eduardo Porto, Beatriz C B Barros, Silvia Luciana F Rosa, Otávio A Sakai, Vagner Roberto Batistela
{"title":"Valorization of agro-industrial wastes of sugarcane bagasse and rice husk for biosorption of Yellow Tartrazine dye.","authors":"Débora H Micheletti, João Gabriel S Andrade, Carlos Eduardo Porto, Beatriz C B Barros, Silvia Luciana F Rosa, Otávio A Sakai, Vagner Roberto Batistela","doi":"10.1590/0001-3765202420231308","DOIUrl":"https://doi.org/10.1590/0001-3765202420231308","url":null,"abstract":"<p><p>The use of agro-industrial wastes as biosorbents is a promising alternative for sustainable, economical and effective adsorption. However, few studies evaluate the use of Brazilian agro-industrial waste as biosorbents without physicochemical pre-treatment. This study explored the potential of sugarcane bagasse (SCB) and rice husk waste (RHW) as low-cost biosorbents for yellow tartrazine dye removal. Characterization of the materials were carried out using ATR-FTIR, SEM, pHPZC and lignocellulosic composition. Cellulose and hemicellulose were the major constituents of both materials. By the Box-Behnken experimental design, the response surfaces indicated maximum removal of 60.1% for SCB and 83.1% for RHW. While the qmax of SCB and RHW for tartrazine were relatively low at 2.45 ± 0.03 mg g-1 and 3.55 ± 0.02 mg g-1, respectively, the potential for achieving higher dye removals by increasing the adsorbent dosage in large-scale applications warrants further investigation. For both biosorbents, the pseudo-second-order kinetic model and Brouers-Sotolongo isotherm provided the best fit for the data, and the adsorption processes were spontaneous and exothermic. In conclusion, SCB and RHW demonstrated high tartrazine removal, promoting sustainable agro-industrial waste management.</p>","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"96 suppl 3","pages":"e20231308"},"PeriodicalIF":1.1,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142811927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization of dark septate endophytic fungi Periconia macrospinosa isolated from roots of sugarcane in São Paulo, Brazil. 巴西圣保罗甘蔗根中深隔内生真菌大棘周孢的鉴定。
IF 1.1 4区 综合性期刊
Anais da Academia Brasileira de Ciencias Pub Date : 2024-12-06 eCollection Date: 2024-01-01 DOI: 10.1590/0001-3765202420231367
Luana C Silva, Orivaldo José Saggin-Júnior, Marco Aurélio C Carneiro, Eliane Maria R DA Silva, Jerri Édson Zilli, Ricardo Luis L Berbara
{"title":"Characterization of dark septate endophytic fungi Periconia macrospinosa isolated from roots of sugarcane in São Paulo, Brazil.","authors":"Luana C Silva, Orivaldo José Saggin-Júnior, Marco Aurélio C Carneiro, Eliane Maria R DA Silva, Jerri Édson Zilli, Ricardo Luis L Berbara","doi":"10.1590/0001-3765202420231367","DOIUrl":"https://doi.org/10.1590/0001-3765202420231367","url":null,"abstract":"<p><p>Dark Septate Endophytic (DSE) fungi can benefit plants by optimizing nutrient uptake, biosynthesis of phytohormones-like compounds, and stress relief such as toxic metals. The objective was to characterize in vitro 57 strains of the DSE Periconia macrospinosa isolated from sugarcane roots, indicating the most promising in solubilizing phosphate sources, growing in different metal and vinasse contents, and producing molecules related to indoleacetic acid (IAA). The strains were from the Embrapa Agrobiology Fungi Collection. Over 35% of the strains solubilize calcium phosphate, highlighting A356 and A155. No strain solubilizes aluminum phosphate. Three strains did not grow in the presence of Cd (A333, A334, A163), but A226, A332, and A423 stand out showing high growth with Cd. All strains grew in the presence of Cu, Zn, and Vinasse. A163, A164, and A328 were even stimulated by Cu addition. A331 and A335 showed a marked growth decrease with Zn. All strains are highly adapted to grow in vinasse presence. A257 and A226 produced the highest amount of IAA. The most biotechnological potential strains are indicated by presenting high growth under Cd, Cu, Zn, and vinasse stress, associated with a high tolerance index to these pollutants, further calcium phosphate solubilization, or IAA production.</p>","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"96 suppl 3","pages":"e20231367"},"PeriodicalIF":1.1,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142811921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bioestratinomic Classification and Genesis of Shell Beds (Coquinas) from the Santa Marta Formation (Upper Cretaceous) of James Ross Island, Antarctica. 南极洲詹姆斯罗斯岛上白垩统圣玛尔塔组壳层生物组学分类及成因。
IF 1.1 4区 综合性期刊
Anais da Academia Brasileira de Ciencias Pub Date : 2024-12-06 eCollection Date: 2024-01-01 DOI: 10.1590/0001-3765202420240692
Luiz Carlos Weinschütz, Renato P Ghilardi, Alexander W A Kellner, Juliana M Sayão
{"title":"Bioestratinomic Classification and Genesis of Shell Beds (Coquinas) from the Santa Marta Formation (Upper Cretaceous) of James Ross Island, Antarctica.","authors":"Luiz Carlos Weinschütz, Renato P Ghilardi, Alexander W A Kellner, Juliana M Sayão","doi":"10.1590/0001-3765202420240692","DOIUrl":"https://doi.org/10.1590/0001-3765202420240692","url":null,"abstract":"<p><p>Shell beds, or coquinas, have a complex origin, limiting their utility in paleoecology. However, such accumulations can serve as crucial paleoenvironmental indicators, since their bioestratinomic and diagenetic properties explain the physical-chemical and biological processes of their formation, as well as the ancient environments linked to their development. In 2016, the PALEOANTAR Project sampled coquinas from the James Ross Island (Antarctic Peninsula) in Passo São José (PSJ - San José Way) and Muro do Castelo (MDC - Castle Wall), two new localities with outcrops of the lower Lachman Crags Member, Santa Marta Formation, Marambio Group, Cretaceous of Larsen Basin. The paleontological content and sedimentary structures indicate a shallow marine depositional system. The PSJ coquina are composed by gastropods bioclasts, with predominantly dense/loose packing. The MDC presents a larger variety of bioclasts with bivalve dominance on a loose packing and conglomeratic horizons, that varies from granule to pebble. Sedimentary and biostratinomic features observed in samples from both localities indicate their genesis from high-energy events, characterized as a proximal tempestite. These descriptions allow a more accurate reconstruction of the depositional environments, highlighting the importance of these rocks in the geological record during the Cretaceous of Antarctica.</p>","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"96 suppl 2","pages":"e20240692"},"PeriodicalIF":1.1,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142811737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Toward Enhanced Antibiotic Efficacy: Exploring the Synergistic Potential of Marine-Derived Lectins Against Human Pathogenic Bacteria. 提高抗生素疗效:探索海洋来源凝集素对人类致病菌的协同作用潜力。
IF 1.1 4区 综合性期刊
Anais da Academia Brasileira de Ciencias Pub Date : 2024-12-06 eCollection Date: 2024-01-01 DOI: 10.1590/0001-3765202420240072
Rômulo F Carneiro, Pedro Arthur S Tabosa, José Gabriel S Cândido, Vinícius Paulino P Menezes, Pedro Abilio V Rocha Júnior, Alexandre L Andrade, Mayron A Vasconcelos, Edson H Teixeira, Celso S Nagano, Alexandre H Sampaio
{"title":"Toward Enhanced Antibiotic Efficacy: Exploring the Synergistic Potential of Marine-Derived Lectins Against Human Pathogenic Bacteria.","authors":"Rômulo F Carneiro, Pedro Arthur S Tabosa, José Gabriel S Cândido, Vinícius Paulino P Menezes, Pedro Abilio V Rocha Júnior, Alexandre L Andrade, Mayron A Vasconcelos, Edson H Teixeira, Celso S Nagano, Alexandre H Sampaio","doi":"10.1590/0001-3765202420240072","DOIUrl":"https://doi.org/10.1590/0001-3765202420240072","url":null,"abstract":"<p><p>This study aimed to assess the combined antibacterial effect of lectins and antibiotics on S. aureus ATCC 25923, multidrug-resistant E. coli ATCC 11303 and S. aureus ATCC 700698. Using the checkerboard assay, we evaluated the antibacterial effects of eight lectins isolated from marine organisms combined with two common antibiotics, oxacillin and tetracycline, on three virulent bacterial strains. Initially, none of the tested lectins exhibited antibacterial effects when used individually. However, when combined with antibiotics, the lectins exhibited synergistic, additive, antagonistic, or no interaction. Overall, the tested lectins alone had no effect on the efficacy of oxacillin. On the other hand, different lectins in combination with tetracycline potentiated its antimicrobial effect. Lectins from red algae of the Bryothamnium genus, for example, exhibited the most significant synergistic effects, reducing the minimum inhibitory concentration (MIC) of tetracycline by up to 16 times. Lectins from the Hypnea genus also reduced the MIC of tetracycline. Our findings suggest that some lectins binding to complex carbohydrates containing fucosylated cores (α1-6) are excellent candidates to boost the efficacy of some antibiotics.</p>","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"96 4","pages":"e20240072"},"PeriodicalIF":1.1,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142811916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
On the potential of glaciochemical analysis of Joinville Island firn core for the sea ice reconstruction around the northern Antarctic Peninsula. Joinville岛冰芯冰川化学分析在南极半岛北部海冰重建中的潜力
IF 1.1 4区 综合性期刊
Anais da Academia Brasileira de Ciencias Pub Date : 2024-12-06 eCollection Date: 2024-01-01 DOI: 10.1590/0001-3765202420230751
Alexandre S DE Alencar, Heitor Evangelista, Sérgio J Gonçalves, Jefferson C Simões, Israel Felzenszwalb, Alberto Setzer, Heber R Passos
{"title":"On the potential of glaciochemical analysis of Joinville Island firn core for the sea ice reconstruction around the northern Antarctic Peninsula.","authors":"Alexandre S DE Alencar, Heitor Evangelista, Sérgio J Gonçalves, Jefferson C Simões, Israel Felzenszwalb, Alberto Setzer, Heber R Passos","doi":"10.1590/0001-3765202420230751","DOIUrl":"https://doi.org/10.1590/0001-3765202420230751","url":null,"abstract":"<p><p>The Antarctic Peninsula is undergoing rapid climate changes, impacting its surrounding marine ecosystem. At that site, sea ice plays a crucial role in this ecosystem by serving as a habitat for organisms and influencing primary productivity. Studying sea ice variability and primary productivity is essential for understanding environmental changes in Antarctica. This research focused on Joinville Island, located at the tip of the Antarctic Peninsula, where meteorological data and glaciochemical analysis were conducted on snow/firn cores for Cl-, Na+, Ca2+, Mg2+, SO4 2-, NO3 -, K+, MSA, NH4 + and F- to retrieve recent past environmental variabilities. The study revealed that Joinville Island experienced a net accumulation rate of 0.40 meters per year in water equivalent between 1993 and 2005. In snow/firn cores, Na+ correlated with both wind strength and sea ice extent (r=0.59 and r=0.66, respectively) while correlations were higher for MSA and Cl- with respect to sea ice (r=0.80 and r=0.74, respectively), considering both the Weddell and Amundsen-Bellingshausen sub-sectors. This analysis contributes to our understanding of sea ice dynamics and its influence on primary productivity in the area.</p>","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"96 suppl 2","pages":"e20230751"},"PeriodicalIF":1.1,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142811755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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