Annals of the New York Academy of Sciences最新文献

The critical role of melody and harmony in sleep induction: Direct evidence from electroencephalogram-based analysis. 旋律和和声在睡眠诱导中的关键作用：来自脑电图分析的直接证据。

IF 5.2 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-05-06 DOI: 10.1111/nyas.15334

Yuncheng Ge,Zengyao Yang,Hechong Su,Jie Miu,Jieren Xie,Ran Zhao,Shuang Liu,Chengcheng Han,Sicong Zhang,Guanghua Xu

{"title":"The critical role of melody and harmony in sleep induction: Direct evidence from electroencephalogram-based analysis.","authors":"Yuncheng Ge,Zengyao Yang,Hechong Su,Jie Miu,Jieren Xie,Ran Zhao,Shuang Liu,Chengcheng Han,Sicong Zhang,Guanghua Xu","doi":"10.1111/nyas.15334","DOIUrl":"https://doi.org/10.1111/nyas.15334","url":null,"abstract":"Insomnia, prevalent in contemporary society, is characterized by difficulties in sleep initiation and maintenance, leading to fatigue, depression, and impaired cognitive function. Although research has demonstrated the sleep induction effects of certain musical genres, the neurophysiological mechanisms through which musical constituents, namely, melody, harmony, and rhythm, induce sleep remain inconclusive. To elucidate how musical constituents influence sleep onset, we used both subjective and objective measures, including the Pittsburgh Sleep Quality Index and Karolinska Sleepiness Scale as the former and electroencephalography (EEG) analysis as the latter. The EEG data showed that melody and harmony significantly enhance sleep quality, particularly impacting the theta band and the dispersion entropy in the temporal lobes. Conversely, the effect of rhythm in sleep induction appeared less significant, with minimal activity observed in the frontal and parietal lobes. We believe the data provide a foundation for innovative approaches to music composition that emphasize melody and harmony to enhance the therapeutic potential of music in sleep management, while de-emphasizing the role of rhythm. The findings also support adapting traditional musical forms, such as classical music, for sleep induction purposes and the development of sleep aid music composition rooted in Western music theory.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"21 1","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143915058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Designing social media content recommendation algorithms for societal good 为社会利益设计社交媒体内容推荐算法

IF 5.2 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-05-05 DOI: 10.1111/nyas.15359

Jana Lasser, Nikolaus Poechhacker

引用次数: 0

Engineering artificial microbial consortia for personalized gut microbiome modulation and disease treatment 用于个性化肠道微生物组调节和疾病治疗的工程人工微生物联合体

IF 5.2 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-05-05 DOI: 10.1111/nyas.15352

Timoth Mkilima

{"title":"Engineering artificial microbial consortia for personalized gut microbiome modulation and disease treatment","authors":"Timoth Mkilima","doi":"10.1111/nyas.15352","DOIUrl":"https://doi.org/10.1111/nyas.15352","url":null,"abstract":"The human gut microbiome is a complex ecosystem that plays a vital role in maintaining health and contributing to the pathogenesis of various diseases. This review proposes a transformative approach that involves engineering artificial microbial consortia—precisely designed communities of microorganisms—for personalized modulation of the gut microbiome and targeted therapeutic interventions. By integrating synthetic biology, systems biology, and advanced culturing techniques, tailored microbial consortia can be developed to perform specific functions within the gut, including the production of therapeutic molecules, modulation of immune responses, and competition against pathogenic bacteria. In vitro and in vivo studies indicate that these engineered consortia can effectively restore microbial balance and enhance host resilience. This personalized approach holds immense potential to revolutionize healthcare by addressing the root causes of diseases such as metabolic disorders, inflammatory conditions, and gastrointestinal infections through precise manipulation of the gut microbiome. Future research should focus on rigorous clinical trials to evaluate the safety, efficacy, and long‐term impacts of these engineered consortia in diverse human populations, paving the way for innovative microbial therapies that promote overall health and well‐being.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"94 1","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143905817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The need for scientific leadership and collaboration to enhance social connection: A call to action 需要科学领导和合作以加强社会联系：行动呼吁

IF 5.2 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-05-02 DOI: 10.1111/nyas.15343

Julianne Holt‐Lunstad, Thomas K. M. Cudjoe, Dani Dumitriu, Nicole B. Ellison, Ashwin A. Kotwal, Matthew S. Pantell, Carla M. Perissinotto, Matthew Lee Smith

{"title":"The need for scientific leadership and collaboration to enhance social connection: A call to action","authors":"Julianne Holt‐Lunstad, Thomas K. M. Cudjoe, Dani Dumitriu, Nicole B. Ellison, Ashwin A. Kotwal, Matthew S. Pantell, Carla M. Perissinotto, Matthew Lee Smith","doi":"10.1111/nyas.15343","DOIUrl":"https://doi.org/10.1111/nyas.15343","url":null,"abstract":"The United States faces a growing crisis of social disconnection, marked by increasing rates of loneliness, social isolation, and declining social capital. This has profound implications for public health, as social connection is critical to individual well‐being and societal functioning. The “loneliness epidemic,” as described by the US Surgeon General, is intertwined with broader challenges such as mental health crises, substance abuse, and sociopolitical issues. Although evidence highlights the importance of social connection for health outcomes, efforts to address social disconnection remain fragmented. This article provides context about the status of social disconnection in America and justifies the need for science to promote social connection from the perspectives of a scientific leadership council (SLC). This call to action proposes coordinated efforts to: (1) galvanize efforts to employ scientific evidence to design solutions and policies to address social disconnection; (2) establish the role of a US‐based SLC, an interdisciplinary collaborative for evidence‐based leadership; and (3) advocate for unified efforts and harmonization to close the gap between evidence and implementation. Additionally, this article proposes setting measurable national goals aligned with the Healthy People 2030 framework to monitor progress and drive systemic change, transforming the current landscape and building a more connected future.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"38 1","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143901493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Time spent alone and loneliness in Mexican‐origin youth: The role of social relationships and personality 墨西哥裔青年的独处时间和孤独感：社会关系和个性的作用

IF 5.2 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-05-01 DOI: 10.1111/nyas.15348

Geneva M. Jost, Sally Hang, Anna C. Wysocki, Mijke Rhemtulla, Richard W. Robins, Camelia E. Hostinar

{"title":"Time spent alone and loneliness in Mexican‐origin youth: The role of social relationships and personality","authors":"Geneva M. Jost, Sally Hang, Anna C. Wysocki, Mijke Rhemtulla, Richard W. Robins, Camelia E. Hostinar","doi":"10.1111/nyas.15348","DOIUrl":"https://doi.org/10.1111/nyas.15348","url":null,"abstract":"Loneliness is a pressing public health concern, particularly among adolescents and young adults. This preregistered study examined changes in time spent alone from 7th to 12th grade, as well as relationship and personality predictors of time spent alone in adolescence and loneliness in early adulthood, using data from a longitudinal study of 674 Mexican‐origin youth in the United States, a rapidly growing yet understudied demographic. Time spent alone showed linear increases from 7th to 12th grade, with greater increases in time spent alone in high school for youth who spent a high proportion of time alone at the start of high school (9th grade). Greater time spent alone in 9th grade was significantly predicted by gender, lower peer relationship quality, parent–child support, parental warmth, higher parent–child conflict, parental hostility, and youth neuroticism. However, there were no significant predictors of change in time spent alone throughout the course of high school (from 9th to 12th grade). Lastly, loneliness in young adulthood was predicted by spending a high proportion of time alone, higher neuroticism, and lower extraversion in the 9th grade. Thus, time spent alone in adolescence may be a crucial early indicator of later loneliness.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"56 1","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143893576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mass spectrometry reveals age‐dependent collagen decline in murine atria 质谱分析显示小鼠心房年龄依赖性胶原蛋白下降

IF 5.2 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-04-29 DOI: 10.1111/nyas.15341

Nathalie Ringström, Charlotte Edling, Giovanna Nalesso, Javier Barallobre‐Barreiro, Kamalan Jeevaratnam

{"title":"Mass spectrometry reveals age‐dependent collagen decline in murine atria","authors":"Nathalie Ringström, Charlotte Edling, Giovanna Nalesso, Javier Barallobre‐Barreiro, Kamalan Jeevaratnam","doi":"10.1111/nyas.15341","DOIUrl":"https://doi.org/10.1111/nyas.15341","url":null,"abstract":"The cardiac atrial extracellular matrix (ECM) is central to age‐associated cardiac remodeling and subsequent decline in cardiac functioning. Despite this, the composition of the atrial ECM and how it changes with age is not yet known. This study utilized mass spectrometry to evaluate the composition of murine atria in young (12 weeks) and old (77 weeks) C57BL/6J mice. The tissue was decellularized, ECM and ECM‐associated proteins were extracted with GuHCl, and proteins were deglycosylated to enable identification of glycosylated peptides. Two hundred and thirty‐seven ECM and ECM‐associated proteins were found to be significantly differentially expressed with age. Some proteins (MMP9, S100A9, VWA3A, CTSD, CCL8) were more than threefold increased with age, proteoglycans were modestly decreased, while the overall collagen content was markedly decreased. STRING network mapping of physical associations predicted that both PLOD3 and PDGFA interact with the collagens that decreased with age. The results suggest that the mechanism behind age‐associated atrial stiffness is not due to an increase in collagen content as previously believed, but an increase in cross‐linking, potentially facilitated by PLOD3. Additionally, several of the significant proteins have not previously been associated with cardiac aging and thus are potential drug targets for age‐associated cardiac fibrosis and other age‐associated conditions.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"35 1","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143884602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of artificial intelligence in general, and large language models specifically, for understanding addictive behaviors 人工智能在理解成瘾行为方面的作用，特别是大型语言模型

IF 5.2 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-04-29 DOI: 10.1111/nyas.15337

Christian Montag, Haibo Yang, Anise M. S. Wu, Raian Ali, Jon D. Elhai

引用次数: 0

Correction to “Neurostimulation improves reading and alters communication within reading networks in dyslexia” 对“神经刺激提高阅读能力并改变阅读网络中的交流”的更正

IF 5.2 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-04-28 DOI: 10.1111/nyas.15361

引用次数: 0

Detecting loneliness among late adolescents: Validation and testing of a detection tool based on the UCLA Loneliness Scale 晚期青少年孤独感的检测：基于UCLA孤独感量表的检测工具的验证与测试

IF 5.2 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-04-28 DOI: 10.1111/nyas.15316

Anne Bo, Berit Kjærside Nielsen, Astrid Fyrstenborg Christensen, Julie Christiansen, Pamela Qualter, Mathilde Graulund Severinsen, Mathias Lasgaard

{"title":"Detecting loneliness among late adolescents: Validation and testing of a detection tool based on the UCLA Loneliness Scale","authors":"Anne Bo, Berit Kjærside Nielsen, Astrid Fyrstenborg Christensen, Julie Christiansen, Pamela Qualter, Mathilde Graulund Severinsen, Mathias Lasgaard","doi":"10.1111/nyas.15316","DOIUrl":"https://doi.org/10.1111/nyas.15316","url":null,"abstract":"The high prevalence of loneliness among adolescents, combined with their tendency to conceal it, highlights the need for strategies that identify and support those youth who experience loneliness. This study aimed to validate and test a detection tool for late adolescents within educational settings in Denmark. The tool, which was based on nine items from the UCLA Loneliness Scale (UCLA-9), underwent a three-stage refinement and testing process. In Stage 1, psychometric analyses and cognitive interviews investigated the reliability, validity, and usability of the tool among adolescents ages 16–20 years; potential cut-off scores for identification of cases on the three-dimensional scale were explored. Stage 2 involved a feasibility test in three educational institutions. Field observations and qualitative interviews with participants offered insights and recommendations for implementation of the tool in educational settings. Stage 3 involved 1728 students engaged in the Danish Lift program run in three municipalities. Among those youth, the refined UCLA-9 demonstrated robust psychometric properties, identifying 9% of adolescents as cases with a cut-off score of ≥10 on each subscale. The UCLA-9 showed promise in identifying adolescents experiencing loneliness, which often co-occurred with poor mental health. Challenges remain in determining appropriate cut-off scores for the identification of cases.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"9 1","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143885024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Using the process model of eco-anxiety in group work 小组工作中生态焦虑的过程模型

IF 5.2 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-04-28 DOI: 10.1111/nyas.15344

Panu Pihkala

{"title":"Using the process model of eco-anxiety in group work","authors":"Panu Pihkala","doi":"10.1111/nyas.15344","DOIUrl":"https://doi.org/10.1111/nyas.15344","url":null,"abstract":"Group work is regarded as an especially promising method for engaging with eco-anxiety and other difficult eco-emotions. This article introduces a new method for facilitated group work based on the process model of eco-anxiety and ecological grief (hereafter, the process model). The method combines elements from timeline exercises, social learning, spectrum line methods, and somatic methods. Observations and feedback from a pilot workshop are used to develop the method further. Participants explored their eco-anxiety journeys in small groups. The phases and dimensions of the process model were printed on paper, and people could move in space while they reflected on them. The participants were encouraged to experiment with somatic movements and sounds. The possible balance or imbalance between action, distancing (including self-care), and grieving (including other emotional engagement) was explored. The workshop ended with creative co-thinking about how to find more balance. This method was clearly useful for the participants, but more research is needed to explore its use with different audiences. This method can be facilitated by people other than therapists if they have suitable skills, but it also allows for in-depth use in therapy and psychological interventions. Variations of using the method or parts of it are discussed.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"40 1","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143885025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0