Heliyon最新文献

{"title":"Advancements in integral inequalities of Ostrowski type via modified Atangana-Baleanu fractional integral operator.","authors":"Gauhar Rahman, Muhammad Samraiz, Kamal Shah, Thabet Abdeljawad, Yasser Elmasry","doi":"10.1016/j.heliyon.2024.e41525","DOIUrl":"10.1016/j.heliyon.2024.e41525","url":null,"abstract":"<p><p>Convexity and fractional integral operators are closely related due to their fascinating properties in the mathematical sciences. In this article, we first establish an identity for the modified Atangana-Baleanu (MAB) fractional integral operators. Using this identity, we then apply Jensen integral inequality, Young's inequality, power-mean inequality, and Hölder inequality to prove several new generalizations of Ostrowski type inequality for the convexity of <math><mo>|</mo> <mi>ℵ</mi> <mo>|</mo></math> . From the primary findings, we also deduced a few new special cases. The results of this investigation are expected to indicate new advances in the study of fractional integral inequalities.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"11 1","pages":"e41525"},"PeriodicalIF":3.4,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11755054/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dog demography and ecology with reference to rabies in the Amhara region, Ethiopia.","authors":"Liuel Yizengaw Adnie, Wudu Temesgen Jemberu, Adane Bahiru Woreta, Adugna Berju, Araya Mengistu, Zeleke Tesema Wondie, Wassie Molla, Sefinew Alemu Mekonnen","doi":"10.1016/j.heliyon.2024.e41582","DOIUrl":"10.1016/j.heliyon.2024.e41582","url":null,"abstract":"<p><p>Knowledge of domestic dog ecology and demography has been recognized as central to the design of an effective rabies control program. The study was conducted to assess owned dogs' ecology and demography and to identify predictors associated with dog ownership and rabies occurrence in the Amhara region, Ethiopia.</p><p><strong>Method: </strong>ology: The study employed dog census and questionnaire surveys of 907 households selected using a multistage sampling technique from six rural and six urban districts of the Amhara region, Ethiopia. The ecology and demography of owned dogs in the selected areas were recorded and described using descriptive statistics. Mixed-effect logistic regression models were used to identify factors associated with dog ownership and rabies occurrence.</p><p><strong>Results: </strong>A total of 6609 dogs were estimated from 42 kebeles in the 12 study districts. The male-to-female ratio of dogs was 1.7:1.0, and the mean age of dogs was 3.2 years. The proportion of households who owned at least one dog was 5.9 %. The average number of dogs per dog-owned household was 1.3. Dog to household ratio was 1.0:13.0, and dog to human ratio was 1.0:48.5. The majority of the dog owners (97 %) keep dogs for home guard and livestock herding. Only 57 % of the dogs were confined, and 16 % of them were vaccinated. Ninety-one percent of the dog owners did not practice neutering and spaying for dog population control. Religion, livestock ownership pattern, and occupation were associated with dog ownership (p < 0.05). Community residence and age of respondents were associated with rabies occurrence (p < 0.05), while zone was associated with both dog ownership and rabies occurrence at p-value <0.05.</p><p><strong>Conclusions: </strong>The study indicated a low dog population relative to humans, which might make dog-based rabies control manageable. But at the same time, most dogs were not properly managed (confined and vaccinated), which calls for more awareness about responsible dog ownership to reduce zoonotic disease risk, including rabies. Generally, the study provides useful information about the demography and ecology of owned dogs in relation to rabies for making proper and effective rabies control strategies and is important to design the spatial distribution of rabies vaccination in dogs. However, as the study did not include stray dogs, which have great contributions to the spread of rabies, the information should be used with this caveat into consideration.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"11 1","pages":"e41582"},"PeriodicalIF":3.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11755056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Repair effects of offcut-carbon-fiber-powder-modified PU-PMMA copolymer on flexure-after-impact behaviors of composite laminate.","authors":"Shang-Nan Tsai, Hsin-Ting Chiang","doi":"10.1016/j.heliyon.2024.e41476","DOIUrl":"10.1016/j.heliyon.2024.e41476","url":null,"abstract":"<p><p>Polymer matrix composites are popular for their lightweight and high strength. Poly (methyl methacrylate) (PMMA), known for its transparency, can be toughened with polyurethane (PU) to expand its applications. This study further strengthened PU-PMMA by adding carbon fiber powder from offcut fabrics (oCFP), enhancing mechanical and adhesion properties. Tensile, flexural, and lap-shear tests were conducted to investigate the effects of the oCFP on the mechanical and adhesion properties of the PU-PMMA resin. The oCFP-modified PU-PMMA was then used in scarf repair to assess its effectiveness on the impacted composite laminates. Tensile and flexural tests showed that 1 wt% oCFP improved tensile strength from 38 MPa to 43.31 MPa and flexural strength from 56.02 MPa to 82.21 MPa, while further addition of oCFP led to reductions in these strengths. Although oCFP-modified PU-PMMA did not significantly restore the impacted laminates' flexural strength, the repairing effect was still more pronounced than that of a commercial epoxy adhesive, demonstrating potential as a repair or structural adhesive.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"11 1","pages":"e41476"},"PeriodicalIF":3.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11754172/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Energy consumption prediction using modified deep CNN-Bi LSTM with attention mechanism.","authors":"Adel Binbusayyis, Mohemmed Sha","doi":"10.1016/j.heliyon.2024.e41507","DOIUrl":"10.1016/j.heliyon.2024.e41507","url":null,"abstract":"<p><p>The prediction of energy consumption in households is essential due to the reliance on electrical appliances for daily activities. Accurate assessment of energy demand is crucial for effective energy generation, preventing overloads and optimizing energy storage. Traditional techniques have limitations in accuracy and error rates, necessitating advancements in prediction techniques. To enhance prediction accuracy, a proposed smart city system utilizes the Household Energy Consumption dataset, employing deep learning algorithms. In the beginning, data pre-processing addresses missing values and performs feature scaling for normalizing independent variables. Followed by that, Modified Deep CNN-Bi-LSTM (Convolutional Neural Network and Bi-directional Long Short Term Memory) with attention mechanism is utilized for regression which extracts temporal and spatial complex features. Deep CNN extracts features impacting energy consumption whereas Bi-LSTM with attention layer finds suitability for regression as it is capable of modelling irregular trends in the time-series components, where the attention mechanism is implemented to enhance the decoder's ability to selectively focus on the most relevant segments of the input sequence. This is achieved through a weighted integration of all encoded input trajectories, allowing the model to dynamically emphasize the vectors that carry the highest significance for accurate predictions. Based on regression outcomes from analysis taken in hourly, daily and monthly time intervals, enhanced prediction accuracy is estimated through evaluation metrics such as MSE (Mean Square Error), MAPE (Mean Absolute Percentage Error) and RMSE (Root Mean Square Error) which determines the efficacy of the system, where Specifically, the proposed model achieves MSE of 0.123, MAE of 0.22, and MAPE of 324.12. Furthermore, this model demonstrates a training time of 692.12 s and a prediction time of just 1.87 s. Therefore, present research highlights the critical need for accurate energy consumption prediction in households, driven by the increasing reliance on electrical appliances in daily life.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"11 1","pages":"e41507"},"PeriodicalIF":3.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11755059/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of transcutaneous electric nerve stimulation on pain after episiotomy. A systematic review and meta-analysis.","authors":"Elisa López-Campos, Mercedes Soto-González, Alejandra Alonso-Calvete, Iria Da Cuña-Carrera","doi":"10.1016/j.heliyon.2024.e41577","DOIUrl":"10.1016/j.heliyon.2024.e41577","url":null,"abstract":"<p><strong>Background: </strong>Episiotomy is a surgical intervention performed during the second stage of labor to facilitate the baby's exit through the birth canal. There are different reasons that lead <b>to an</b> episiotomy; however, it is recommended <b>to be</b> performed occasionally and not systematically, since it may produce negative effects such as pain. Different therapies have been described to reduce this pain, including transcutaneous electrical nerve stimulation (TENS).</p><p><strong>Objective: </strong>To conduct a systematic review and meta-analysis about the effects of Transcutaneous Electric Nerve Stimulation (TENS) on pain after episiotomy.</p><p><strong>Methods: </strong>The databases PubMed, Cochrane, Scopus, Cinhal, PEDro and Web of Science were consulted using the terms \"Episiotomy\" and \"Transcutaneous Electric Nerve Stimulation\". The methodological quality was analyzed with the PEDro scale. A random-effects model was used to carry out the meta-analysis.</p><p><strong>Findings: </strong>88 studies were obtained and after applying the selection criteria, 6 were included in the systematic review and 5 in the meta-analysis. There were significant positive effects in decreasing the pain for TENS in comparison with pre-intervention (SMD = 1.19 [95 % CI - 0.33 to 2.05]; p < 0.01; I2 = 96 %), control group (SMD = -1.07 [95 % CI - -1.53 to -0.6]; p < 0.01; I2 = 82 %) and placebo group (SMD = -1.33 [95 % CI - -2.32 to -0.34]; p < 0.01; I2 = 86 %).</p><p><strong>Conclusion: </strong>TENS appears to have a positive effect in reducing pain after 1 h of an episiotomy. The location of the electrodes does not seem to be relevant in the effects.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"11 1","pages":"e41577"},"PeriodicalIF":3.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11754501/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adherence to integrated care using the 'Atrial fibrillation Better Care' pathway in asymptomatic patients with atrial fibrillation improves clinical outcomes: A report from the prospective COOL-AF registry.","authors":"Yodying Kaolawanich, Arjbordin Winijkul, Ahthit Yindeengam, Poom Sairat, Gregory Y H Lip, Rungroj Krittayaphong","doi":"10.1016/j.heliyon.2024.e41586","DOIUrl":"10.1016/j.heliyon.2024.e41586","url":null,"abstract":"<p><strong>Background: </strong>Identifying asymptomatic patients with atrial fibrillation (AF) poses a challenge, and their optimal management is less certain, despite similar outcomes to symptomatic AF patients. The 'Atrial fibrillation Better Care' (ABC) pathway has been recently proposed as a holistic or integrated care approach for the comprehensive management of symptomatic patients with AF. We aimed to determine the use of the ABC pathway on clinical outcomes in asymptomatic patients with AF.</p><p><strong>Methods: </strong>This is a prospective multicenter registry of patients with non-valvular AF in Thailand conducted between 2014 and 2017. Patients were characterized based on AF-related symptoms at enrollment and their adherence or non-adherence to the ABC pathway. Follow-up data were collected for 3 years to examine the composite endpoint (all-cause death, ischemic stroke/transient ischemic attack [TIA]/systemic embolism [SE], and major bleeding), and the impact of adherence to the ABC pathway.</p><p><strong>Results: </strong>Of a total of 3405 patients included in the study, 785 (23 %) (mean age 69.0 years, 63.7 % male) were asymptomatic at enrollment. Among these asymptomatic patients, 346 (44 %) were adherent to the ABC pathway. Adherence to the ABC pathway was associated with a significantly lower rate of composite endpoints compared to non-adherence (hazard ratio [HR] 0.63, 95 % confidence interval [CI] 0.45-0.90, p = 0.01). Adherence to the ABC pathway was also associated with lower all-cause mortality rates (HR 0.55, 95 % CI 0.35-0.85, p = 0.007). After adjusting for age, gender, and baseline comorbidities, adherence to the ABC pathway remained significantly associated with a lower rate of composite endpoints (HR 0.69, 95 % CI 0.49-0.98, p = 0.03) and all-cause death (HR 0.58, 95 % CI 0.38-0.90, p = 0.01) compared to non-adherence. Subgroup analyses based on sex, age, AF type, risk scores, and comorbidities consistently demonstrated lower hazard ratios for the composite endpoint among patients who were adherent to the ABC pathway.</p><p><strong>Conclusions: </strong>In patients with AF who were asymptomatic, adherence to the ABC pathway was associated with a lower composite endpoint of all-cause death, ischemic stroke/TIA/SE, and major bleeding. This benefit was seen irrespective of sex, age, AF type, risk scores, and comorbidities.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"11 1","pages":"e41586"},"PeriodicalIF":3.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11755037/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of RAD51AP1 as a key gene in hepatitis B virus-associated hepatocellular carcinoma.","authors":"Meiling Wan, Yonghong Wang, Xiaoling Liu, Yaling Li, Cunliang Deng, Changfeng Sun","doi":"10.1016/j.heliyon.2024.e41594","DOIUrl":"10.1016/j.heliyon.2024.e41594","url":null,"abstract":"<p><strong>Background: </strong>Hepatocellular carcinoma (HCC) is a significant global health concern, with chronic hepatitis B virus (HBV) infection being a major contributor. Understanding the mechanisms of HBV-associated HCC is crucial to improving the prognosis and developing effective treatments.</p><p><strong>Methods: </strong>HBV-associated HCC datasets (GSE19665, GSE121248, GSE55092, GSE94660, and TCGA-LIHC) acquired from public databases were mined to identify key driver genes by differentially expressed gene analysis, weighted gene co-expression network analysis (WGCNA), followed by protein-protein interaction network analysis, Lasso-Cox regression analysis, and randomforestSRC algorithm. Then, in vitro experiments including CCK-8 assay, wound healing, and Transwell assay were performed to explore the functions and mechanisms.</p><p><strong>Results: </strong>RAD51AP1 was identified as a specific key gene linked to the progression of HBV-associated HCC. High expression of RAD51AP1 was associated with worse overall survival (OS) in patients with HBV-associated HCC, but not in patients with non-HBV-associated HCC. Mechanistically, RAD51AP1 forms a potential ceRNA axis with LINC01419 and miR-8070, where LINC01419 acts as a molecular sponge for miR-8070 to upregulate RAD51AP1. HBV infection can enhance the LINC01419/miR-8070/RAD51AP1 axis, and LINC01419 overexpression conversely promotes HBV replication. The ceRNA axis and HBV synergistically promote the proliferation and metastasis of HBV-associated HCC cells. Furthermore, LINC01419 or RAD51AP1 knockdown, and miR-8070 overexpression in HepG2.2.15 cells significantly attenuated the Wnt/β-catenin signaling.</p><p><strong>Conclusions: </strong>The LINC01419/miR-8070/RAD51AP1 axis promotes the HBV-associated HCC progression through an HBV-boosted positive feedback loop and Wnt/β-catenin signaling. These findings provide novel insights into the underlying mechanisms and may offer potential diagnostic and therapeutic targets in HBV-associated HCC.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"11 1","pages":"e41594"},"PeriodicalIF":3.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11755046/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The therapeutic potential of vitamins A, C, and D in pancreatic cancer.","authors":"Alban Piotrowsky, Markus Burkard, Hendrik Schmieder, Sascha Venturelli, Olga Renner, Luigi Marongiu","doi":"10.1016/j.heliyon.2024.e41598","DOIUrl":"10.1016/j.heliyon.2024.e41598","url":null,"abstract":"<p><p>The pancreatic ductal adenocarcinoma (PDAC) is among the deadliest tumor diseases worldwide. While treatment options have generally become more diverse, little progress has been made in the treatment of PDAC and the median survival time for patients with locally advanced PDAC is between 8.7 and 13.7 months despite treatment. The aim of this review was to explore the therapeutic potential of complementing standard therapy with natural or synthetic forms of vitamins A, C, and D. The therapeutic use of vitamins A, C, and D could be a promising addition to the treatment of PDAC. For all three vitamins and their derivatives, tumor cell-specific cytotoxicity and growth inhibition against PDAC cells has been demonstrated in vitro and in preclinical animal models. While the antitumor effect of vitamin C is probably mainly due to its pro-oxidative effect in supraphysiological concentrations, vitamin A and vitamin D exert their effect by activating nuclear receptors and influencing gene transcription. In addition, there is increasing evidence that vitamin A and vitamin D influence the tumor stroma, making the tumor tissue more accessible to other therapeutic agents. Based on these promising findings, there is a high urgency to investigate vitamins A, C, and D in a clinical context as a supplement to standard therapy in PDAC. Further studies are needed to better understand the exact mechanism of action of the individual compounds and to develop the best possible treatment regimen. This could contribute to the long-awaited progress in the treatment of this highly lethal tumor entity.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"11 1","pages":"e41598"},"PeriodicalIF":3.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11754517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advanced photoluminescent nanomaterials for targeted bioimaging of cancer cells.","authors":"Tooba Mohammadi, Hadi Gheybalizadeh, Elaheh Rahimpour, Jafar Soleymani, Vahid Shafiei-Irannejad","doi":"10.1016/j.heliyon.2024.e41566","DOIUrl":"10.1016/j.heliyon.2024.e41566","url":null,"abstract":"<p><p>The investigation of changes in the membrane of cancer cells holds great potential for biomedical applications. Malignant cells exhibit overexpression of receptors, which can be used for targeted drug delivery, therapy, and bioimaging. Targeted bioimaging is one the most accurate imaging methods with a non-invasive nature, allowing for localization of the malignant cell without disrupting cellular integrity. Also, bioimaging has the potential to enhance the quality of established imaging techniques like magnetic resonance imaging (MRI). The utilization of nanoparticles in targeted bioimaging enhances the imaging quality and efficiency. Biocompatible nanoparticles can easily penetrate cell membranes, while they can be readily functionalized on their surfaces toward cell receptors. This study reviews reports on the application of new advanced photoluminescent materials for targeted bioimaging using the cell membrane receptors. Also, the limitations and advantages of the application of nanoparticles have been reviewed along with the clinical consideration of their uses in bioimaging.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"11 1","pages":"e41566"},"PeriodicalIF":3.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11754178/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of ChatGPT usage on nursing students education: A cross-sectional study.","authors":"Alberto Gonzalez-Garcia, David Bermejo-Martinez, Ana Isabel Lopez-Alonso, Bibiana Trevisson-Redondo, Cristian Martín-Vázquez, Silvia Perez-Gonzalez","doi":"10.1016/j.heliyon.2024.e41559","DOIUrl":"10.1016/j.heliyon.2024.e41559","url":null,"abstract":"<p><strong>Background: </strong>The use of artificial intelligence tools, such as ChatGPT, is on the rise in nursing education. In the field of healthcare, ChatGPT can offer unique opportunities to enhance the learning and clinical practice of nursing students. However, it is still necessary to explore how this tool affects students' performance and perception in their nursing education.</p><p><strong>Objective: </strong>The objective of this study was to evaluate the impact of ChatGPT on nursing students' education and determine how it influences their learning outcomes.</p><p><strong>Design: </strong>This study employed a quantitative cross-sectional design.</p><p><strong>Setting: </strong>The study was conducted in the Bachelor of Nursing program at the University of León, Spain.</p><p><strong>Participants: </strong>Ninety-eight nursing students enrolled in the Nursing Care and Services Management course during the second semester of 2024 participated in the study.</p><p><strong>Methods: </strong>Data were collected using three validated questionnaires that assessed sociodemographic characteristics, knowledge of artificial intelligence, and perceptions of using ChatGPT as an educational tool. The data were analyzed using IBM SPSS Statistics, version 29.1.</p><p><strong>Results: </strong>Students who used ChatGPT showed a significant improvement in their academic grades (p < 0.05). Additionally, 89.5 % of the students reported significant improvements in their academic performance. Women perceived ChatGPT as especially useful for completing academic tasks (85.14 % versus 50.00 % in men, p = 0.003). A positive correlation was observed between prior use of ChatGPT and GPA (ρ = 0.240, p = 0.026).</p><p><strong>Conclusions: </strong>ChatGPT is a valuable tool that enhances the learning and satisfaction of nursing students. Its integration into nursing education programs not only boosts academic performance but also promotes the adoption of technological innovations in professional training. Continuous incorporation of AI tools in education is recommended to improve academic outcomes and prepare students for evolving healthcare environments.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"11 1","pages":"e41559"},"PeriodicalIF":3.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11755058/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}