化学•材料最新文献

{"title":"Corrigendum to 'Multifunctional composite soluble microneedle patch based on \"one stone, three birds\" strategy for promoting the healing of infectious wounds' [Colloids Surf. B: Biointerfaces, vol. 241 (2024) 114049].","authors":"Weili Yang, Min Cao, Wenxin Wang, Ningning Diao, Xiaowei Liu, Yue Hu, Xinxin Wang, Tianying Sun, Chunjing Guo, Daquan Chen","doi":"10.1016/j.colsurfb.2024.114467","DOIUrl":"10.1016/j.colsurfb.2024.114467","url":null,"abstract":"","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"248 ","pages":"114467"},"PeriodicalIF":5.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142875660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cascade of phase transitions in a dipeptide supramolecular assembly triggered by a single fatty acid.","authors":"Kaifeng Guo, Liang Gao, Jinbo Fei","doi":"10.1016/j.colsurfb.2024.114480","DOIUrl":"10.1016/j.colsurfb.2024.114480","url":null,"abstract":"<p><p>Significant progress has been achieved with diversity of short peptide supramolecular assemblies. However, their programmable phase modulation by single stimulus remains a great challenge. Herein, we demonstrate a dipeptide supramolecular system undergoes sequentially coupled phase transitions upon hydrogen bonding association and dissociation triggered by a single fatty acid. To be specific, fatty acid at a low specific ratio mediates gel-crystal transformation of the dipeptide supramolecular assembly by rearrangement of hydrogen bonding interactions. Moreover, fatty acid at a high specific ratio induces crystal-sol transition by protonation of the dipeptide, generating strong electrostatic repulsion to cleave hydrogen bonding interactions. Remarkably, the cascade of phase transitions enables spontaneous solid-liquid separation of the dipeptide from one dispersion phase and further dissolution in another in a capture and release fashion. In contrast, it is not facilitated by individual phase transition. Our work creates competitive pathways to achieve integration of phase transitions in a simple dipeptide supramolecular system. It is useful to deeply understand the dynamic and complex biomolecular condensates in nature and with important implications for efficient collection of biomolecules.</p>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"248 ","pages":"114480"},"PeriodicalIF":5.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142908899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Zeolite-like algal biochar nanoparticles for enhanced antibiotics removal: Sorption mechanisms and theoretical calculations.","authors":"Jiaxing Sun, Lili Ji, Jiaxin Liu, Hao Yang, Teng Dong, Tongxin Liu","doi":"10.1016/j.colsurfb.2024.114475","DOIUrl":"10.1016/j.colsurfb.2024.114475","url":null,"abstract":"<p><p>In the study, Sargassum horneri (S. horneri) was used to create a novel zeolite-like algal biochar (KSBC). KSBC with doping of N, O, S, Al, and Si, displayed zeolite-like properties, including well-developed porosity, a high specific surface area (1137.60 m²/g), and a large number of oxygen-containing functional groups. According to bath adsorption experiments, ciprofloxacin (CIP) and tetracycline (TC) had maximum adsorption capacities of 352.936 and 265.385 mg/g, respectively, on KSBC. The adsorption behavior of the two antibiotics on KSBC was consistent with the Freundlich isotherm model and the pseudo-first-order kinetic model. According to the density functional theory calculations, the -OH, Si, N, and Al in KOH could change the electronic structure and increase absorbability. Additionally, pore adsorption, hydrogen bonding, complexation, electrostatic interaction, and π-π electron-donor-acceptor (EDA) interaction were the adsorption mechanisms of CIP and TC via KSBC. S. horneri algal biochar demonstrated encouraging promise as an adsorbent for eliminating antibiotics from wastewater.</p>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"248 ","pages":"114475"},"PeriodicalIF":5.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142908908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Super hydrophilic and super oleophobic carbon nanotube/TiO₂ composite membranes for efficient separation of algal-derived oil/water emulsions.","authors":"Ali Ahmadi, Soheila Shokrollahzadeh, Abdolreza Samimi, Alireza Ashori","doi":"10.1016/j.colsurfb.2024.114491","DOIUrl":"10.1016/j.colsurfb.2024.114491","url":null,"abstract":"<p><p>The separation of oil from microalgae aqueous emulsions is a critical step in producing algal-derived biofuels and nutraceuticals. This study presents the development of super hydrophilic and super oleophobic composite membranes to efficiently separate algal oil from oil/water emulsions. Carbon nanotubes (CNTs) were functionalized with polydopamine (PDA), polyethylene glycol (PEG), and titanium dioxide (TiO₂) nanoparticles and coated onto a mixed cellulose ester (MCE) substrate to fabricate the composite membranes. Two distinct incorporation methods were employed for TiO_2; direct nanoparticle incorporation and surface coating onto the CNT/PDA network. The membranes were comprehensively characterized using FTIR, SEM, EDS, contact angle measurements, and AFM analysis. The synthesized MCE@CNT/PDA/NP-TiO₂ membrane exhibited super hydrophilicity with a water contact angle of 6.3° and underwater super oleophobicity with oil contact angles up to 172°. Membrane performance evaluation using a Nannochloropsis salina microalgae oil/water emulsion revealed excellent flux up to 9238 L m^-2 h^-1 bar^-1 and oil rejection as high as 98.6 % for the TiO₂-incorporated membranes. Additionally, these membranes demonstrated superior antifouling properties, maintaining over 90 % of initial flux even after five separation cycles. Incorporating TiO₂ nanoparticles significantly enhanced the membrane's hydrophilicity, oleophobicity, antifouling capability, and stability under extreme pH conditions. The developed composite membranes show great potential for efficient and cost-effective separation of algal oil from microalgae cultivation systems.</p>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"248 ","pages":"114491"},"PeriodicalIF":5.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A multifunctional graphene oxide-based nanodrug delivery system for tumor targeted diagnosis and treatment under chemotherapy-photothermal-photodynamic synergy.","authors":"Huirui Zhu, Ruolan Feng, Dongkun Li, Meijuan Shi, Nan Wang, Yijie Wang, Yumeng Guo, Xiaoning Li, Tao Gong, Rui Guo","doi":"10.1016/j.colsurfb.2024.114479","DOIUrl":"10.1016/j.colsurfb.2024.114479","url":null,"abstract":"<p><p>Traditional cancer therapies, such as chemotherapy, often lack specificity, resulting in severe toxic side effects and limited therapeutic efficacy. There is an urgent need to develop innovative multifunctional nanomedicine carriers that integrate precise diagnosis, targeted therapy, real-time monitoring, and the synergistic effects of multiple therapeutic approaches. In this study, a composite nanodrug delivery system (GO-HA-Ce6-GNRs) based on graphene oxide (GO) was innovatively prepared, which was functionalized with the targeting molecule hyaluronic acid (HA), the photosensitizer chlorin e6 (Ce6), and the photothermal material gold nanorods (GNRs). In vitro and in vivo experiments demonstrated that GO-HA-Ce6-GNRs exhibited excellent biocompatibility, remarkable photothermal and photodynamic properties, high drug-loading capacity for the anticancer drug doxorubicin hydrochloride (DOX), and a dual pH/near-infrared (NIR) light-responsive drug release profile. Additionally, GO-HA-Ce6-GNRs displayed enhanced tumor targeting and efficient fluorescence imaging capabilities. Notably, GO-HA-Ce6-GNRs@DOX manifested highly effective chemotherapy-photothermal-photodynamic synergistic anti-tumor effects in both MCF-7 and HeLa cancer cells as well as U14 tumor-bearing mice. Therefore, GO-HA-Ce6-GNRs@DOX represents a promising nanoplatform for tumor diagnosis and therapy, significantly improving the safety and efficacy of chemotherapy. This work provides a solid foundation and theoretical basis for the development of new targeted nano drug delivery systems that integrate both diagnosis and treatment.</p>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"248 ","pages":"114479"},"PeriodicalIF":5.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142908896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robust visualization of membrane protein by aptamer mediated proximity ligation assay and Förster resonance energy transfer.","authors":"Ying Li, Meiqi Qian, Yuping Cheng, Xue Qiu","doi":"10.1016/j.colsurfb.2024.114486","DOIUrl":"10.1016/j.colsurfb.2024.114486","url":null,"abstract":"<p><p>In situ cell imaging plays a crucial role in studying physiological and pathological processes of cells. Proximity ligation assay (PLA) and rolling circle amplification (RCA) are commonly used to study the abundance and interactions of biological macromolecules. The most frequently applied strategy to visualize the RCA products is with single-fluorophore probe, however, cellular auto-fluorescence and unbound fluorescent probes could interfere with RCA products, leading to non-specific signals. Here, we present a novel approach combining aptamer mediated PLA, RCA, and Förster Resonance Energy Transfer (FRET), namely Apt-PLA-RCA-FRET, for sensitive in situ imaging and analysis of the abundances and interactions of membrane proteins such as tetraspanin CD63 and human epidermal growth factor receptor 2 (HER2). Apt-RCA-FRET was initially designed to show its ability to assess the abundance of target proteins on different cells. Dual functional oligonucleotides served as both the aptamer for recognizing specific membrane proteins and the primer of circular DNA for following RCA process, and the resulting RCA products were subsequently imaged by FRET signals from Cy3 to Cy5 probes which hybridized sequentially on them. FRET was demonstrated to show its great potential to resist the interferences of nonspecific fluorescence compared to single-fluorophore strategies. PLA was then introduced to Apt-RCA-FRET to investigate the spatial localization of different proteins on cell membrane and their interactions. Our approach utilizing aptamer as membrane proteins recognition element simply converted the abundance of proteins into nucleic acid signals and facilitated the following signal amplification, thus it serves as an important alternative to methods typically based on antibody and presents a more robust and sensitive method for analyzing the abundances of different cell membrane proteins and their spatial localization, which offers valuable insights into physiological and pathological processes of cells.</p>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"248 ","pages":"114486"},"PeriodicalIF":5.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142929995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integration of EMAP-II-targeted anti-angiogenesis and photodynamic therapy using zinc phthalocyanine nanosystem for enhanced cancer treatment.","authors":"Liyun Chen, Linlin Li, Hailong Zhao, Hao Li, Jiahui Li, Chao Li, Yang Zhou, Luxuan Yang, Jun Liang, Honglian Zhang, Juan Li, Peng Xu, Cai Yuan, Zhenhua Liu, Mingdong Huang, Longguang Jiang","doi":"10.1016/j.colsurfb.2024.114493","DOIUrl":"10.1016/j.colsurfb.2024.114493","url":null,"abstract":"<p><p>Angiogenesis provides essential nutrients and oxygen to tumors during tumorigenesis, facilitating invasion and metastasis. Consequently, inhibiting tumor angiogenesis is an established strategy in anti-cancer therapy. In this study, we engineered a dual-function nanosystem with both antiangiogenic and photodynamic properties. We transformed the hydrophobic photosensitizer zinc phthalocyanine (PS) into a hydrophilic form via protein renaturation, resulting in a novel photosensitizer: Monocyte-Activating Polypeptide-II (EMAP-II:PS@NPs). Characterization through dynamic light scattering (DLS) and UV-vis spectroscopy showed that these nanoparticles exhibited uniform size and stability, and enhanced solubility. We further demonstrated that EMAP-II:PS@NPs effectively target tumor vascular endothelia causing intracellular photodynamic cytotoxicity. Notably, EMAP-II:PS@NPs achieved effective ablation of solid tumors at significantly reduced dosages of drugs compared to conventional therapies, due to their potent apoptotic effects on light-exposed cells. This study highlights the potential of combining anti-angiogenic activity with phototherapy, paving the way for innovative cancer treatment strategies.</p>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"248 ","pages":"114493"},"PeriodicalIF":5.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142942105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experiments and modelling of pulmonary surfactant disruption by aerosolised compounds.","authors":"Hugh Barlow, Sreyoshee Roy Sengupta, Maria Teresa Baltazar, Jorid B Sørli","doi":"10.1016/j.colsurfb.2024.114482","DOIUrl":"10.1016/j.colsurfb.2024.114482","url":null,"abstract":"<p><p>Within the deep lung, pulmonary surfactant coats the air-liquid interface at the surface of the alveoli. This complex mixture of amphiphilic molecules and proteins modifies the surface tension and mechanical properties of this interface to assist with breathing. In this study, we examine the effects on pulmonary surfactant function by two industrially used compounds composing surfactants and polymers. Using an experimental method previously developed to imitate the in vivo exposure in the alveoli, we quantify the change in the dilational rheology of the pulmonary surfactant due to the introduction of two widely used chemicals; Benzalkonium Chloride (BAC) and Polyhexamethylene Biguanide (PHMB). We observe that these chemicals alter the dilational rheology of the surfactant monolayer. Using a mechanistic theory, we are able to semi-quantitatively model the changes induced by the introduction of these compounds to the pulmonary surfactant.</p>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"248 ","pages":"114482"},"PeriodicalIF":5.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142982024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tumor-targeted nanosystem with hypoxia inducible factor 1α inhibition for synergistic chemo-photodynamic therapy against hypoxic tumor.","authors":"Ruifeng Zeng, Rui Zhou, Lu Zhen, Jinshuai Lan, Zhe Li, Donghao Gu, Wenlong Nie, Yi Shen, Minquan Zhang, Tong Zhang, Yue Ding","doi":"10.1016/j.colsurfb.2024.114456","DOIUrl":"10.1016/j.colsurfb.2024.114456","url":null,"abstract":"<p><p>Photodynamic therapy (PDT) holds an essential role in the therapy of tumors. However, PDT consumes tissue oxygen and diminishes its own efficacy by inducing tumor hypoxia through the HIF-1α/VEGF pathway. Therefore, overcoming the photodynamic exacerbation of tumor hypoxia could reverse tumor microenvironment and enhance PDT. In this study, BC-PDA/HA loaded with bufalin (BUF) and chlorin e6 (Ce6) were developed for synergistic cancer chemo-photodynamic therapy. BC-PDA/HA, modified with hyaluronic acid (HA), exhibited CD44-targeting capability and enhanced cellular uptake in vitro. Moreover, in the acidic tumor microenvironment, BC-PDA/HA could on-demand release Ce6 and BUF, inducing PDT upon 660 nm irradiation. Simultaneously, the released BUF not only served as a chemotherapeutic agent, but also inhibited HIF-1α expression, reversing the PDT-induced tumor hypoxia. Furthermore, compared to free Ce6, BC-PDA/HA enhanced tumor accumulation and retention in vivo. BC-PDA/HA could also effectively improve hypoxia and inhibit tumor angiogenesis to enhance PDT efficacy, demonstrating synergistic chemo-PDT activity. In conclusion, this work provided a novel strategy for synergistic chemo-photodynamic therapy against breast cancer.</p>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"248 ","pages":"114456"},"PeriodicalIF":5.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142890861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sensitive electrochemical detection of glycated hemoglobin (HbA1c) using cobalt metal-organic framework/two-dimensional molybdenum diselenide nanocomposite-based immunosensors amplified by polyoxometalate/DNA aptamer.","authors":"Siriporn Anuthum, Phakorn Papan, Arnat Pasena, Saranphong Yimklan, Chanchanok Aramrat, Padchanee Sangthong, Jaroon Jakmunee, Kontad Ounnunkad","doi":"10.1016/j.colsurfb.2024.114461","DOIUrl":"10.1016/j.colsurfb.2024.114461","url":null,"abstract":"<p><p>Clinical diagnosis and long-term diabetes management are advanced by monitoring glycated hemoglobin A1c (HbA1c) levels. New sensitive sandwich-like immunosensors for the diagnosis of early diabetes toward detecting HbA1c and hemoglobin (Hb) are demonstrated for the first time. DNA aptamers are used for signal amplification in the sensors for the detection of HbA1c and Hb. The immunosensors are constructed by coating with a cobalt-based metal-organic framework (Co-MOF)/two-dimensional molybdenum diselenide (2D MoSe₂) composite onto a working electrode of an ItalSens screen-printed electrode (SPE) inserted into a Sensit/Smart Potentiostat affixed to a smartphone. After the immobilization of the antibodies, the detection is obtained by incubating the resultant SPEs in target solutions and then detecting the response of Keggin-type polyoxometalate (POM) bound on the DNA aptamer chains. In the selected potential window, the POM (silicotungstic acid, H₄[α-SiW₁₂O₄₀]) used in this study exhibits the electron-transfer processes I and II ([α-SiW₁₂O₄₀]^4-/5- and [α-SiW₁₂O₄₀]^5-/6-, respectively) in the acidic buffer electrolyte. Our proposed device demonstrates exceptional performance in the recovery test of %HbA1c in healthy human plasma samples. The sensitivity, selectivity, and stability of this immunosensor are exceedingly outstanding, which makes it one of the potential analytical devices for diagnosing early diabetes by a %HbA1c assay.</p>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"248 ","pages":"114461"},"PeriodicalIF":5.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142870773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}