TiO₂/PANI-based sensing electrode for ethanol detection in human sweat to monitor liver functioning.

IF 5.6 2区医学 Q1 BIOPHYSICS

Colloids and Surfaces B: Biointerfaces Pub Date : 2025-12-01 Epub Date: 2025-08-05 DOI:10.1016/j.colsurfb.2025.114991

Bhavya Padha, Isha Yadav, Sandeep Arya

引用次数: 0

Abstract

Wearable sensors for detecting ethanol volatile organic compounds (VOCs) in sweat offer a non-invasive approach to monitor liver health. In line with this goal, a titanium dioxide/polyaniline (TiO₂/PANI) nanocomposite-based sensor electrode was developed for real-time ethanol detection under standard conditions (300 K, 1 atm). The thin film, deposited on a conductive fabric, was characterized for phase, structure, and morphology. Electrochemical tests showed high sensitivity, with a detection limit of 23.62 ppb and quantification of 71.59 ppb. The sensor demonstrated excellent reproducibility, stability, and selectivity across various ethanol concentrations. It effectively distinguished between sweat samples from healthy and liver-affected individuals and maintained performance over 100 days under varying humidity and temperature.

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基于二氧化钛/聚苯胺的传感电极，用于人体汗液中乙醇检测以监测肝功能。

用于检测汗液中乙醇挥发性有机化合物（VOCs）的可穿戴传感器为监测肝脏健康提供了一种非侵入性方法。为此，开发了一种二氧化钛/聚苯胺（TiO2/PANI）纳米复合材料传感器电极，用于标准条件下（300 K, 1 atm）的实时乙醇检测。薄膜沉积在导电织物上，对其相、结构和形态进行了表征。电化学试验灵敏度高，检出限为23.62 ppb，定量为71.59 ppb。该传感器在不同浓度的乙醇中表现出优异的再现性、稳定性和选择性。它有效地区分了健康个体和肝脏受损个体的汗液样本，并在不同的湿度和温度下保持了100多天的表现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Colloids and Surfaces B: Biointerfaces 生物-材料科学：生物材料

CiteScore

11.10

自引率

3.40%

发文量

730

审稿时长

42 days

期刊介绍： Colloids and Surfaces B: Biointerfaces is an international journal devoted to fundamental and applied research on colloid and interfacial phenomena in relation to systems of biological origin, having particular relevance to the medical, pharmaceutical, biotechnological, food and cosmetic fields. Submissions that: (1) deal solely with biological phenomena and do not describe the physico-chemical or colloid-chemical background and/or mechanism of the phenomena, and (2) deal solely with colloid/interfacial phenomena and do not have appropriate biological content or relevance, are outside the scope of the journal and will not be considered for publication. The journal publishes regular research papers, reviews, short communications and invited perspective articles, called BioInterface Perspectives. The BioInterface Perspective provide researchers the opportunity to review their own work, as well as provide insight into the work of others that inspired and influenced the author. Regular articles should have a maximum total length of 6,000 words. In addition, a (combined) maximum of 8 normal-sized figures and/or tables is allowed (so for instance 3 tables and 5 figures). For multiple-panel figures each set of two panels equates to one figure. Short communications should not exceed half of the above. It is required to give on the article cover page a short statistical summary of the article listing the total number of words and tables/figures.