Nanotechnologies in Russia最新文献

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Effect of Copper(II) Oxide Nanoparticles on the Growth and Development of Sugar Beet Microclones 纳米氧化铜对甜菜微无性系生长发育的影响
IF 0.8
Nanotechnologies in Russia Pub Date : 2026-04-03 DOI: 10.1134/S2635167625602074
O. V. Zakharova, E. N. Vasilchenko, T. P. Fedulova, N. N. Cherkasova, G. V. Grigoriev, E. Yu. Koiava, N. S. Strekalova, A. A. Gusev
{"title":"Effect of Copper(II) Oxide Nanoparticles on the Growth and Development of Sugar Beet Microclones","authors":"O. V. Zakharova,&nbsp;E. N. Vasilchenko,&nbsp;T. P. Fedulova,&nbsp;N. N. Cherkasova,&nbsp;G. V. Grigoriev,&nbsp;E. Yu. Koiava,&nbsp;N. S. Strekalova,&nbsp;A. A. Gusev","doi":"10.1134/S2635167625602074","DOIUrl":"10.1134/S2635167625602074","url":null,"abstract":"<p>We studied the effect of copper oxide nanoparticles (CuO NPs) of elliptical shape, 80–100 nm in size (CuO 1) and flake-shaped, 100–500 nm in cross-sectional size and 10–20 nm in thickness (CuO 2), on sugar beet (<i>Beta vulgaris</i> L.) micro-sprouts of male-sterile (MS forms) and Owen-type sterility fixers (O-type) under tissue culture conditions in vitro. NPs were added to the nutrient growth medium at concentrations of 10 and 100 mg/L. We found a decrease in the growth indices of regenerants under the influence of NPs, regardless of the type of plants and particles. At the same time, the addition of 10 mg/L NPs significantly increased the multiplication coefficient. For MS-form plants, the maximum multiplication rate (+77% to the control) was observed with the introduction of CuO 1, while for O-type plants, an increase in the rate by 96% was noted in the variant with CuO 2. Analysis of copper bioaccumulation showed an increase in the element content in sugar beet microclones, and if a two-fold increase was noted for CuO 1, then in the case of CuO 2, the copper content increased 4 times for MS-form plants and 5 times for O-type plants. Thus, we have shown for the first time the prospects of using CuO NPs to increase the efficiency of the clonal micropropagation procedure of sugar beet plants. However, further studies of the safety of their use are required, which is associated with the identified accumulation of copper in regenerated plants.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"20 1","pages":"S97 - S106"},"PeriodicalIF":0.8,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147606663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Use of Suspensions Based on Metal Oxide Nanoparticles and Abies Sibirica Oil for the Anticorrosive Treatment of Metals 基于金属氧化物纳米颗粒和西伯利亚冷杉油的悬浮液在金属防腐处理中的应用
IF 0.8
Nanotechnologies in Russia Pub Date : 2026-04-03 DOI: 10.1134/S2635167625602098
G. V. Lyamina, I. N. Shevchenko, L. Pen, X. Chen, Ya Liu, I. A. Bozhko
{"title":"The Use of Suspensions Based on Metal Oxide Nanoparticles and Abies Sibirica Oil for the Anticorrosive Treatment of Metals","authors":"G. V. Lyamina,&nbsp;I. N. Shevchenko,&nbsp;L. Pen,&nbsp;X. Chen,&nbsp;Ya Liu,&nbsp;I. A. Bozhko","doi":"10.1134/S2635167625602098","DOIUrl":"10.1134/S2635167625602098","url":null,"abstract":"<p>Siberian fir oil, also known as <i>Abies sibirica</i>, is used as a dispersion medium for suspensions containing titanium oxide and zinc oxide nanoparticles. Corrosion tests were conducted on bronze and St3 (S235JR) steel samples using accelerated tests in a solution of concentrated acids, including optical microscopy, gravimetric analysis, and X-ray diffraction. Additionally, dilute acid solutions were used for Tafel diagram analysis and impedance spectroscopy. Based on the results of the corrosion studies, it was determined that fir oil significantly improves the corrosion protection of St3 steel in a 0.1 M HCl solution by 74.2%. The addition of zinc oxide nanoparticles further enhances this protection to 90.4%. For bronze, fir oil alone provides a corrosion protection of 47.9% in a 0.1 M H<sub>2</sub>SO<sub>4</sub> solution, while the addition of titanium oxide nanoparticles increases this protection to an impressive 98.6%.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"20 1","pages":"S157 - S162"},"PeriodicalIF":0.8,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147606866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biosensing as an Important Direction for Development of the Bioeconomy in Russia 生物传感是俄罗斯生物经济发展的重要方向
IF 0.8
Nanotechnologies in Russia Pub Date : 2026-04-03 DOI: 10.1134/S2635167625602220
A. N. Reshetilov, Yu. V. Plekhanova, S. E. Tarasov, R. G. Vasilov
{"title":"Biosensing as an Important Direction for Development of the Bioeconomy in Russia","authors":"A. N. Reshetilov,&nbsp;Yu. V. Plekhanova,&nbsp;S. E. Tarasov,&nbsp;R. G. Vasilov","doi":"10.1134/S2635167625602220","DOIUrl":"10.1134/S2635167625602220","url":null,"abstract":"<p>With the ever-increasing population of the planet, the burden on natural ecosystems and the biosphere as a whole is inevitably increasing. The traditional economic paradigm based on fossil fuels has almost exhausted itself, and there is an urgent need to switch to alternative sustainable models of production and consumption. The bioeconomy, an area that combines biological, technological, and economic knowledge, should play an important role in this process. This work analyzes the key role of biosensors and biofuel cells in its development. The analysis is carried out within the context of a new national project of the Russian Federation “Bioeconomy” and its five main areas: agriculture, healthcare, high-value bioproducts, energy, and waste recycling. It is shown that biosensors and biofuel cells are cross-cutting technologies capable of greatly increasing the efficiency of each area, and the active implementation of these nature-like technologies is a strategic factor in achieving Russia’s technological sovereignty and building a circular economy.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"20 1","pages":"S3 - S12"},"PeriodicalIF":0.8,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147606658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bio-Ecovillages As an Integrated Model for Living and Territorial Development Based on Bioeconomy Principles 生物生态村:基于生物经济原理的人居与国土开发一体化模式
IF 0.8
Nanotechnologies in Russia Pub Date : 2026-04-03 DOI: 10.1134/S2635167625602281
T. N. Gaeva, R. G. Vasilov
{"title":"Bio-Ecovillages As an Integrated Model for Living and Territorial Development Based on Bioeconomy Principles","authors":"T. N. Gaeva,&nbsp;R. G. Vasilov","doi":"10.1134/S2635167625602281","DOIUrl":"10.1134/S2635167625602281","url":null,"abstract":"<p>The development of progressive models of social and natural living using key technologies of the sixth technological paradigm (biotechnology, nanotechnology, nature-based technologies, robotics, information technology, AI, etc.) will significantly contribute to overcoming the consequences of the global polycrisis caused by an imbalance in the “nature–technology–society” system. This review provides a retrospective analysis of the idea of harmonizing technosphere–biosphere contradictions by creating sustainable models of living and improving the human environment through technological and urban-planning solutions. The principle features of the bio-ecovillage concept as the most promising, innovative, and sustainable forms of organized living are considered. The foundational ideas of the concept of bio-ecovillages are presented, as well as an assessment of their role in shaping the bioeconomy sector, addressing issues of territorial and environmental security, and solving pressing problems of socio-economic and demographic development in the Russian Federation.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"20 1","pages":"S34 - S43"},"PeriodicalIF":0.8,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147606662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intermolecular Interactions of Graphene Nanosheets with Enzymes of the Danio rerio Antioxidant System 石墨烯纳米片与酶的分子间相互作用
IF 0.8
Nanotechnologies in Russia Pub Date : 2026-04-03 DOI: 10.1134/S2635167625602396
P. D. Timkin, D. D. Kotelnikov, A. A. Penzin, I. E. Pamirsky, S. M. Ugai, E. Yu. Koiava, V. V. Chaika, K. S. Golokhvast
{"title":"Intermolecular Interactions of Graphene Nanosheets with Enzymes of the Danio rerio Antioxidant System","authors":"P. D. Timkin,&nbsp;D. D. Kotelnikov,&nbsp;A. A. Penzin,&nbsp;I. E. Pamirsky,&nbsp;S. M. Ugai,&nbsp;E. Yu. Koiava,&nbsp;V. V. Chaika,&nbsp;K. S. Golokhvast","doi":"10.1134/S2635167625602396","DOIUrl":"10.1134/S2635167625602396","url":null,"abstract":"<p>This paper presents the results of a study on the physicochemical characteristics of the binding between single-layer graphene nanosheets (GNs) and typical enzymes of the antioxidant system of the fish <i>Danio rerio</i>. The enzymes chosen as target proteins were superoxide dismutase 1 (SOD1), glutathione peroxidase 8 (Gpx8) and catalase (Cat). Virtual molecular structures of the target enzyme and GN were modeled and optimized. Two GN sizes were studied: 25 × 25 and 35 × 35 Å. Using UniProt DB and PrankWeb, annotated binding amino acid residues were compared with amino acid residues associated with GN obtained from the prediction results. For all proteins except Gpx8, the topology of amino acid residues potentially involved in binding to nanosheets was precisely localized. The number of amino acid residues involved in the formation of the molecular cavity ranged from 13 to 30. Molecular interactions between enzymes, proteins and GN were predicted using the rigid molecular docking method using AutoDock software. The study showed the formation of more stable GN-enzyme complexes for 25 × 25 Å GN with fairly low binding energies. The Gibbs free energy values for each combination of GN-enzyme complexes range from –10.1 to ‒15.9 kcal/mol. The article discusses the potential biological effects of the studied carbon-based GNs on the antioxidant system of fish <i>D. rerio</i>. The presented approach seems promising for studying and predicting the cytotoxicity of pollutants based on graphene nanoparticles.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"20 1","pages":"S199 - S203"},"PeriodicalIF":0.8,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147606664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Strengthening of Freshwater Ice with Nanofibrous Cellulose and Polyvinylpyrrolidone 纳米纤维纤维素和聚乙烯吡咯烷酮对淡水冰的强化作用
IF 0.8
Nanotechnologies in Russia Pub Date : 2026-04-03 DOI: 10.1134/S2635167625602426
V. V. Rodaev, V. M. Vasyukov, A. O. Zhigachev, A. A. Samodurov, N. M. Kurkina, A. I. Tyurin
{"title":"Strengthening of Freshwater Ice with Nanofibrous Cellulose and Polyvinylpyrrolidone","authors":"V. V. Rodaev,&nbsp;V. M. Vasyukov,&nbsp;A. O. Zhigachev,&nbsp;A. A. Samodurov,&nbsp;N. M. Kurkina,&nbsp;A. I. Tyurin","doi":"10.1134/S2635167625602426","DOIUrl":"10.1134/S2635167625602426","url":null,"abstract":"<p>The effect of nanofibrous cellulose and polyvinylpyrrolidone with different molar masses in the concentration range of 0.003–3 wt % on the compressive strength and fracture behavior of fabricated ice composites in comparison with pure freshwater ice is studied. It is found that, with an increase in the mass fraction of the filler from 0.3 to 1 wt % for all ice composites, a transition from brittle to ductile fracture occurs. The maximum strengthening effect is achieved with the addition of 0.3 wt % of the filler to ice. The highest compressive strength is observed in the ice composites with cellulose nanofibers and long polyvinylpyrrolidone molecules, exceeding the compressive strength of pure ice by approximately 1.7 times.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"20 1","pages":"S163 - S167"},"PeriodicalIF":0.8,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147606867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study of Intermolecular Interactions of Enzyme of the Antioxidant System Danio rerio and CdS and ZnS Nanoparticles 抗氧化体系酶与CdS和ZnS纳米颗粒分子间相互作用的研究
IF 0.8
Nanotechnologies in Russia Pub Date : 2026-04-03 DOI: 10.1134/S2635167625602372
P. D. Timkin, D. D. Kotelnikov, A. A. Penzin, I. E. Pamirsky, S. M. Ugai, E. Yu. Koiava, V. V. Chaika, K. Yu. Kirichenko, K. S. Golokhvast
{"title":"Study of Intermolecular Interactions of Enzyme of the Antioxidant System Danio rerio and CdS and ZnS Nanoparticles","authors":"P. D. Timkin,&nbsp;D. D. Kotelnikov,&nbsp;A. A. Penzin,&nbsp;I. E. Pamirsky,&nbsp;S. M. Ugai,&nbsp;E. Yu. Koiava,&nbsp;V. V. Chaika,&nbsp;K. Yu. Kirichenko,&nbsp;K. S. Golokhvast","doi":"10.1134/S2635167625602372","DOIUrl":"10.1134/S2635167625602372","url":null,"abstract":"<p>The paper presents the results of studying the intermolecular interactions of enzymes of the <i>Danio rerio</i> antioxidant system (superoxide dismutase 1, glutathione peroxidase 8, and catalase) and Cds and ZnS nanoparticles. The virtual molecular structures of target enzymes and metal sulfide nanoparticles were modeled and optimized. For all proteins except glutathione peroxidase 8, the topology of amino acid residues potentially involved in binding to nanotubes was precisely localized. The number of amino acid residues involved in the formation of the molecular cavity ranged from 13 to 30. According to the results of the study, it was found that the formation of nanoparticle-enzyme complexes with average binding energy values from –3.43 to –8.24 kcal/mol is possible. All nanoparticles were characterized by the formation of electrostatic bonds in the ligand-binding sites of proteins, which in general should lead to the same scenario in the form of inhibition of protein function. The presented approach is promising for studying the eco- and cytotoxicity of such pollutants as nanoparticles of cadmium and zinc sulfides.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"20 1","pages":"S119 - S123"},"PeriodicalIF":0.8,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147606933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ecotoxicity Assessment of the Cr2GaC MAX Phase for Bacteria, Microalgae, and Plants Cr2GaC MAX相对细菌、微藻和植物的生态毒性评价
IF 0.8
Nanotechnologies in Russia Pub Date : 2026-04-03 DOI: 10.1134/S2635167625602475
O. V. Zakharova, I. A. Vasyukova, G. V. Grigoriev, L. D. Rodionova, S. M. Tatarko, E. Yu. Koiava, A. A. Gusev
{"title":"Ecotoxicity Assessment of the Cr2GaC MAX Phase for Bacteria, Microalgae, and Plants","authors":"O. V. Zakharova,&nbsp;I. A. Vasyukova,&nbsp;G. V. Grigoriev,&nbsp;L. D. Rodionova,&nbsp;S. M. Tatarko,&nbsp;E. Yu. Koiava,&nbsp;A. A. Gusev","doi":"10.1134/S2635167625602475","DOIUrl":"10.1134/S2635167625602475","url":null,"abstract":"<p>As the applications of MXenes expand, the need for research into the hazards associated with MAX phases increases. This study, for the first time, assessed the effects of the Cr<sub>2</sub>GaC MAX phase (crystal size 200–400 nm) on <i>Escherichia coli</i> bacteria, <i>Chlorella fusca</i> microalgae, and <i>Triticum aestivum</i> plants. A dose-dependent toxic effect of Cr<sub>2</sub>GaC on <i>E. coli</i> bacteria has been established. However, either no effect or a stimulating effect of the Cr<sub>2</sub>GaC MAX phase on the growth, viability, and photosynthetic parameters of <i>C. fusca</i> cultures was observed. Assessment of the effect of Cr<sub>2</sub>GaC on wheat plants also revealed no significant negative impact. These results can be used in the future development of MXene-based products and devices for biotechnology, agriculture, and environmental applications.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"20 1","pages":"S135 - S143"},"PeriodicalIF":0.8,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147606936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lipid Monolayers As a Model of the Interfacial Boundary of the Inner Mitochondrial Membrane 脂质单层作为线粒体内膜界面边界的模型
IF 0.8
Nanotechnologies in Russia Pub Date : 2026-04-03 DOI: 10.1134/S2635167625602438
M. V. Novozhden, S. V. Nesterov, Yu. N Malakhova, A. G. Rogov, R. G. Vasilov
{"title":"Lipid Monolayers As a Model of the Interfacial Boundary of the Inner Mitochondrial Membrane","authors":"M. V. Novozhden,&nbsp;S. V. Nesterov,&nbsp;Yu. N Malakhova,&nbsp;A. G. Rogov,&nbsp;R. G. Vasilov","doi":"10.1134/S2635167625602438","DOIUrl":"10.1134/S2635167625602438","url":null,"abstract":"<p>Langmuir monolayers are a convenient model system for studying some processes occurring at the interface of the inner mitochondrial membrane (IMM). This review summarizes current scientific data on the use of monolayers to model the IMM, with an emphasis on the role of cardiolipin, a unique phospholipid with four acyl chains and two phosphate groups, which plays a key role in IMM structure formation and in the function of oxidative phosphorylation enzymes, and possibly in stabilizing protons at the interface and in their transfer from proton pumps to ATP synthase. The review discusses the advantages of monolayer systems over classical models: the ability to control the degree of lipid compression, the larger interfacial area, and compatibility with almost all detection methods. The key features of cardiolipin in monolayers are described in detail: conical molecular geometry, pH-dependent phase transitions, sensitivity to divalent cations (in particular, calcium), domain formation, and interactions with other components of the membrane/monolayer. Despite the good applicability of monolayer systems, limitations arise because the one-dimensional structure of a monolayer cannot fully reproduce IMM properties. A strategy for further development of monolayer model systems is proposed, including the use of lyso-forms of cardiolipin to optimize molecular geometry, the control of oxidative damage to polyunsaturated lipids, experiments at low pH and physiological ion concentrations, and the application of modern methods for proton generation at the interface (photoacids, or molecules that release protons upon illumination).</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"20 1","pages":"S44 - S54"},"PeriodicalIF":0.8,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147606362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Structural Features of Binding of Single Wall Carbon Nanotubes with Enzymes of Antioxidant System Danio rerio 单壁碳纳米管与抗氧化体系酶结合的结构特征
IF 0.8
Nanotechnologies in Russia Pub Date : 2026-04-03 DOI: 10.1134/S2635167625602360
P. D. Timkin, D. D. Kotelnikov, A. A. Penzin, I. E. Pamirsky, S. M. Ugai, E. Yu. Koiava, V. V. Chaika, K. S. Golokhvast
{"title":"Structural Features of Binding of Single Wall Carbon Nanotubes with Enzymes of Antioxidant System Danio rerio","authors":"P. D. Timkin,&nbsp;D. D. Kotelnikov,&nbsp;A. A. Penzin,&nbsp;I. E. Pamirsky,&nbsp;S. M. Ugai,&nbsp;E. Yu. Koiava,&nbsp;V. V. Chaika,&nbsp;K. S. Golokhvast","doi":"10.1134/S2635167625602360","DOIUrl":"10.1134/S2635167625602360","url":null,"abstract":"<p>The paper presents the results of a study of the physical and chemical characteristics of the binding of single-walled carbon nanotubes (SWNT) with typical enzymes of the antioxidant system of the fish <i>Danio rerio</i>. The enzymes chosen as target proteins were superoxide dismutase 1 (SOD1), glutathione peroxidase 8 (Gpx8) and catalase (CAT). Virtual molecular structures of target enzymes and SWNT were modeled and optimized. Three main types of SWCNTs have been studied: chair conformation (chirality <i>n</i> = <i>m</i> = 7, repeats =9, length ≈22 Å); “zigzag” conformation (chirality <i>n</i> = 7, <i>m</i> = 0, repeats =6, length ≈21 Å; “chiral” conformation (chirality <i>n</i> = 7, <i>m</i> = 3, repeats =1, length ≈37 Å. Comparisons of annotated amino acid residues binding with the prediction of the molecular cavity with amino acid residues conjugated with SWNTs was carried out using UniProt DB and PrankWeb. For all proteins except Gpx8, the topology of amino acid residues potentially involved in binding to nanotubes was accurately localized, ranged from 13 to 30. Molecular interactions between proteins and SWNT s were predicted using the molecular docking method using AutoDock software. The study showed that the formation of generally stable SWNT–enzyme complexes with fairly low binding energy values for each. Combinations of SWNT–enzyme complexes range from –13.41 to ‒18.09 kcal/mol. The potential biological effects of the studied carbon nanotubes on the biochemical and physiological systems of <i>D. rerio</i> fish are discussed. The presented approach is promising for studying pathophysiological models of cytotoxicity.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"20 1","pages":"S114 - S118"},"PeriodicalIF":0.8,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147606367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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