Nanotechnologies in Russia最新文献

{"title":"Comparative Metagenomics for Monitoring the Hidden Dynamics of the Algal-Bacterial Wastewater Community under the Influence of Drugs","authors":"P. A. Zaytsev,&nbsp;B. M. Shurygin,&nbsp;V. A. Rodin,&nbsp;T. V. Panova,&nbsp;M. I. Zvereva,&nbsp;E. V. Skripnikova,&nbsp;A. E. Solovchenko","doi":"10.1134/S2635167624600470","DOIUrl":"10.1134/S2635167624600470","url":null,"abstract":"<p>Modern methods of metagenomics, including those based on long reads of nanopore sequencing, are especially relevant for environmental-monitoring tasks, in particular, for assessing the anthropogenic impact on natural communities of microorganisms. These include algal-bacterial communities that live in water-treatment plants and participate in the biological treatment of wastewater from excess organic waste and nutrients (phosphorus and nitrogen). Metagenomic analysis shows changes in the taxonomic composition and functional profile of the algal-bacterial community when simulating the release of drugs into wastewater: broad-spectrum antibiotics (for example, ceftriaxone) and nonsteroidal anti-inflammatory drugs (for example, diclofenac). The results of metagenomic analysis based on long reads of nanopore sequencing and classical methods of environmental monitoring, including metabarcoding based on short reads on a second-generation sequencing platform, are compared. Nanopore sequencing of the entire metagenome shows a greater biodiversity of samples compared to the DNA metabarcoding of short reads, makes it possible to determine the taxonomic affiliation of particular organisms more accurately, identify groups of eukaryotic oxygenic phototrophs, and also reveal the presence of antibiotic-resistance genes in the community. It is shown that under the influence of medicinal substances, the algal-bacterial community is enriched with antibiotic-resistant bacteria. At the same time, despite maintaining the rate of phosphorus removal, the community’s potential for the removal of nutrients is reduced, which is expressed in a two-order reduction in the relative representation of inorganic-nutrient metabolism genes. Simultaneous exposure to ceftriaxone and excess nutrients in the wastewater leads to the maximum enrichment of antibiotic-resistant organisms, as well as the replacement of cyanobacteria originally present in the community with eukaryotic microalga.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"19 3","pages":"393 - 407"},"PeriodicalIF":0.8,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142540731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dendritic Silver Structures for the SERS Diagnostics of Liquids","authors":"M. Yu. Tsvetkov,&nbsp;A. P. Sviridov","doi":"10.1134/S2635167624601608","DOIUrl":"10.1134/S2635167624601608","url":null,"abstract":"<div><p>The diagnostics and monitoring of trace amounts of technogenic and biological substances are becoming increasingly relevant in the modern world. One approach to solving them is surface-enhanced Raman scattering (SERS). In this work, we propose a variant of manufacturing SERS substrates in the form of dendritic silver nanostructures with the spatial modulation of wettability, which ensures concentration of the analyte upon drying. The proposed technical solutions are tested using rhodamine 6G and 4-aminothiophenol as analytes. The SERS surfaces used for this purpose provide a high measurement sensitivity and are easy and affordable to manufacture.</p></div>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"19 3","pages":"351 - 357"},"PeriodicalIF":0.8,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142540652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toxicity Study of Biogenic Silver Nanoparticles Using Paramecium Caudatum Ciliates","authors":"M. A. Kryuchkova,&nbsp;A. O. Rozhin,&nbsp;E. V. Rozhina","doi":"10.1134/S2635167624601256","DOIUrl":"10.1134/S2635167624601256","url":null,"abstract":"<p>Currently, silver nanoparticles (AgNPs) are increasingly used as biocides, but when released into the environment, they can affect nontarget organisms. In this regard, there is an increasing need to develop the synthesis of AgNPs using biological agents. However, the toxic effect of biogenic AgNPs on aquatic organisms has not been studied in detail. A model is proposed for using the freshwater ciliate <i>Paramecium caudatum</i> as a test organism to assess the toxic effect of AgNPs synthesized using sphagnum moss. The effect of different concentrations of biogenic AgNPs is studied based on the biological responses of paramecia on survival, growth rate, chemotaxis, phagocytosis, and macronucleus morphology. The results show that AgNPs stabilized with sphagnum extract is toxic to ciliates, demonstrating a pronounced dose-dependent effect.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"19 3","pages":"452 - 460"},"PeriodicalIF":0.8,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142540691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resistive Memory in 2T1R Architecture Based on Si MOSFETs and Nanocomposite Memristors","authors":"I. A. Surazhevsky,&nbsp;K. Yu. Chernoglazov,&nbsp;I. V. Alyaev,&nbsp;Yu. V. Grischenko,&nbsp;D. V. Ichyotkin,&nbsp;A. V. Emelyanov,&nbsp;T. E. Grigoriev,&nbsp;A. D. Kalyonov,&nbsp;A. I. Iliasov,&nbsp;V. A. Demin,&nbsp;V. V. Rylkov","doi":"10.1134/S2635167624601657","DOIUrl":"10.1134/S2635167624601657","url":null,"abstract":"<div><p>A manufacturing sequence for the formation of controlled memory in the 2T1R architecture using Si MOSFETs (metal-oxide-semiconductor field-effect transistor) and memristor crossbars based on thin layers of CoFeB-LiNbO₃ nanocomposite and a-LiNbO₃ is developed. It is shown that when using Cu top electrodes in memristors, relatively small resistive-switching voltages and currents (2.5 V and 0.4 mA) are achieved, which are suitable for creating a memory microchip within the MPW technology service (https://mpw.miet.ru/).</p></div>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"19 3","pages":"468 - 474"},"PeriodicalIF":0.8,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142540696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genomic and Genetic Studies of Cultivated Actinidia (Actinidia spp.)","authors":"M. V. Gladysheva-Azgari,&nbsp;N. V. Slobodova,&nbsp;S. V. Tsygankova,&nbsp;I. V. Mitrofanova","doi":"10.1134/S2635167624601141","DOIUrl":"10.1134/S2635167624601141","url":null,"abstract":"<p><i>Actinidia</i> Lindl. is a genus of plants, some species of which are of great economic importance. Varieties of large-fruited <i>Actinidia</i>, known as kiwi (<i>A. deliciosa</i> and <i>A. chinensis</i>), are widely distributed on the world market, however, recently attempts have been made to domesticate small-fruited <i>Actinidia</i>, which in Russia are represented by several far-eastern species. The genomics and genetics of <i>Actinidia</i> are developing in different directions, often in accordance with the needs of breeders. The review describes genomic and genetic studies related to the most important agricultural traits of <i>Actinidia</i>: genetic diversity, chemical composition of fruits, sex coding, response to frost, storage, and transportation of crops.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"19 3","pages":"342 - 350"},"PeriodicalIF":0.8,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142540734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selection of Yeast Strains for the Production of Dry Wines from the Indigenous Grape Variety Kokur White","authors":"A. A. Kolosova,&nbsp;D. Yu. Fedosov,&nbsp;Z. B. Namsaraev,&nbsp;A. A. Korzhenkov,&nbsp;K. O. Petrova,&nbsp;V. M. Pozhidaev,&nbsp;A. V. Kamaev,&nbsp;S. A. Kolosov","doi":"10.1134/S2635167624601128","DOIUrl":"10.1134/S2635167624601128","url":null,"abstract":"<p>The results of studying 55 <i>Saccharomyces cerevisiae</i> yeast strains, intended for the production of dry white wines from the Crimean autochthonous Kokur White variety, are presented. The study involved 49 strains isolated from spontaneously fermented grape must of various grape varieties grown on the Crimean Peninsula, and six strains of yeast obtained from the All-Russian Collection of Industrial Microorganisms of the National Research Center “Kurchatov Institute” and the Magarach Collection of Winemaking Microorganisms of the Magarach All-Russian National Research Institute of Viticulture and Winemaking, Russian Academy of Sciences. As a result, two yeast strains are selected: Su-48 and Y-693. These are the most promising for the production of wines from the Kokur White variety. These strains contributed to the production of oxidation-resistant wines, as well as the preservation of acidity and the development of intense, bright varietal aromas.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"19 3","pages":"416 - 422"},"PeriodicalIF":0.8,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142540728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of New Biocidal Complexes for Antifouling Marine Coatings","authors":"O. A. Zhuravliova,&nbsp;T. A. Voeikova,&nbsp;A. Yu. Vlasova,&nbsp;A. I. Kilochek,&nbsp;E. A. Nikulina,&nbsp;N. V. Tsirulnikova,&nbsp;A. S. Egorov,&nbsp;V. G. Debabov","doi":"10.1134/S2635167623601432","DOIUrl":"10.1134/S2635167623601432","url":null,"abstract":"<p>Biogenic silver nanoparticles (AgNPs) obtained using metal-reducing bacteria <i>Shewanella oneidensis</i> MR-1 and silver-nitrate salts are included in liquid and dry formulations in the composition of such polymeric materials as acrylic paint, epoxy glue, and chelate compounds of copper and zinc with different types of ligands. The preservation of a high level of biocidal activity of AgNPs in the composition of nanocomposite materials in relation to microorganisms of various systematic groups is shown. It is established that the contribution of biogenic AgNPs to the activity level of biocidal metal chelates is 20–25%. For the first time, an assessment of the antimicrobial properties of the original polymer materials is carried out and the different sensitivity of strains to their effects is revealed, which indicates the need to take into account strain specificity when selecting components of a biocidal nanocomposite material.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"19 3","pages":"358 - 365"},"PeriodicalIF":0.8,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142540729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subglobular Structure of Photonic Crystal Nanospheres Grown Based on Amorphous Silica at Different Water/TEOS Molar Ratios in the Initial Mixtures","authors":"I. I. Yurasova,&nbsp;N. I. Yurasov,&nbsp;A. A. Veligzhanin,&nbsp;G. S. Peters,&nbsp;D. R. Strel’tsov,&nbsp;N. K. Galkin,&nbsp;A. N. Zakharov","doi":"10.1134/S2635167624600858","DOIUrl":"10.1134/S2635167624600858","url":null,"abstract":"<p>Photonic crystals obtained by the modified Stöber method with the natural sedimentation of nanospheres is investigated. The surfaces of the silica nanospheres are investigated using atomic-force microscopy. The surfaces of all samples have a cauliflower structure. The structure of the photonic crystals is studied by the method of small-angle synchrotron radiation scattering (SASRS). The SASRS curves exhibit two or three regions with different scattering intensities. Three original techniques for analyzing the data obtained are proposed. Periodicity in the dependence of the logarithm of intensity on the scattering vector at the smallest wavenumbers, related to scattering from nanospheres, is found. The influence of the water/TEOS molar ratio on the size and concentration of these particles is revealed. Particles of two types (nanospheres and subglobules) are observed at low water concentrations (6–8 mol/L), whereas at water concentrations of 13–23 mol/L the particles are of three types (nanospheres, subglobules, and grains). The morphology of the detected particles is estimated.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"19 2","pages":"188 - 196"},"PeriodicalIF":0.8,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142192833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thermoelectric Properties of Zinc Oxide Doped with Aluminum and Nickel Ions","authors":"E. V. Chernyshova,&nbsp;E. A. Kolesnikov,&nbsp;F. Yu. Bochkanov,&nbsp;E. V. Argunov,&nbsp;A. I. Voronin,&nbsp;V. V. Khovaylo","doi":"10.1134/S2635167624600937","DOIUrl":"10.1134/S2635167624600937","url":null,"abstract":"<p>In this work, a thermoelectric material with the nominal composition Zn_0.97Al_0.02Ni_0.01O is synthesized using the chemical coprecipitation method. The synthesized powder consists of the main phase of wurtzite with a small content of Ni_1–<i>z</i>Zn_<i>z</i>O; the change in the crystal-lattice parameters of the main phase indicates the replacement of Zn²⁺ with Al³⁺. The Ni_1–<i>z</i>Zn_<i>z</i>O phase is predominantly located at the grain boundaries, blocking their growth during spark-plasma sintering. The resulting morphology enhances phonon scattering processes, which leads to a decrease in thermal conductivity. The electrical conductivity exhibits activation behavior and increases significantly in comparison with undoped ZnO, because the concentration of charge carriers increases with the substitution of Zn²⁺/Al³⁺. Thus, the chemical coprecipitation method allows one to obtain doped ZnO with an increase in thermoelectric performance of more than 2 times relative to undoped ZnO.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"19 2","pages":"213 - 218"},"PeriodicalIF":0.8,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142192857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Inhibition of the Growth of Breast and Colon Tumors when Blocking VEGFR-1 with Monoclonal Antibodies","authors":"T. A. Shtam,&nbsp;A. V. Demyanov,&nbsp;L. A. Garaeva,&nbsp;S. S. Emelianova,&nbsp;A. V. Nikitina,&nbsp;E. D. Putevich,&nbsp;A. S. Potyseva,&nbsp;M. S. Bidghieva,&nbsp;A. V. Volnitskiy,&nbsp;V. V. Kvanchiani,&nbsp;L. A. Solomina,&nbsp;K. A. Shabalin,&nbsp;E. V. Sergeeva,&nbsp;A. P. Trashkov,&nbsp;Zh. Yu. Sidorova,&nbsp;A. V. Zhahov,&nbsp;V. S. Burdakov,&nbsp;N. A. Verlov,&nbsp;A. L. Konevega","doi":"10.1134/S263516762460086X","DOIUrl":"10.1134/S263516762460086X","url":null,"abstract":"<div><p>Vascular endothelial growth factor receptor-1 (VEGFR-1) plays a critical role in tumor-associated angiogenesis. VEGFR-1 is found on the surface of tumor cells and cells in the tumor microenvironment. Blocking this receptor leads to the suppression of proliferation and increased apoptosis of tumor cells, reduction of tumor vascularization, inhibition of the production of immunosuppressive cytokines by tumor-associated macrophages, and the suppression of tumor invasion and metastasis. The creation of monoclonal antibody drugs that block VEGFR-1 is an urgent task in the development of potential antitumor therapeutic drugs. Target molecules created on the basis of antibodies that bind to VEGFR-1 are a promising basis for the creation of theranostic radiopharmaceuticals for the diagnosis and treatment of malignant neoplasms. To study the therapeutic potential of VEGFR-1 inhibition in breast and colon cancers using antibodies, monoclonal antibodies against recombinant human VEGFR-1 protein are developed. The resulting monoclonal antibodies bind to the VEGFR-1 receptor on the cell surface and effectively inhibit the proliferation of breast and colon cancer cells in vitro, reduce the growth rate of the tumor node in vivo, and prolong the survival of tumor-inoculated mice.</p></div>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"19 2","pages":"291 - 298"},"PeriodicalIF":0.8,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1134/S263516762460086X.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142193180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}