V. V. Butova, T. V. Bauer, V. A. Polyakov, M. A. Gritsai, T. M. Minkina, Z. B. Namsaraev
{"title":"Synthesis of a Capsule for the Targeted Delivery of Active Compounds Based on Metal-Organic Frameworks with a Modified Surface","authors":"V. V. Butova, T. V. Bauer, V. A. Polyakov, M. A. Gritsai, T. M. Minkina, Z. B. Namsaraev","doi":"10.1134/S2635167624602845","DOIUrl":null,"url":null,"abstract":"<p>The aim of this study is to develop nanomaterials based on porous frameworks for the targeted delivery of active compounds. Three metal-organic frameworks (MOFs) ZIF-8, UiO-66-NH<sub>2</sub>, and MIL-100(Fe) are coated with surfactants (SAs) to enhance their bioavailability. The stability of MOFs during modification with SA solutions is studied. Based on data from powder X-ray diffraction and IR spectroscopy, the optimal MOF–SA pairs are identified. The adsorption and desorption dynamics of cationic (methylene blue) and anionic dyes (methyl orange) by the most promising composites are investigated. The obtained results and proposed patterns can be further used for loading active components, such as phytohormones, into MOF pores, considering the specifics of electrostatic interactions and potential binding via functional groups.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"19 1 supplement","pages":"S128 - S137"},"PeriodicalIF":0.8000,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nanotechnologies in Russia","FirstCategoryId":"1085","ListUrlMain":"https://link.springer.com/article/10.1134/S2635167624602845","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Engineering","Score":null,"Total":0}
引用次数: 0
Abstract
The aim of this study is to develop nanomaterials based on porous frameworks for the targeted delivery of active compounds. Three metal-organic frameworks (MOFs) ZIF-8, UiO-66-NH2, and MIL-100(Fe) are coated with surfactants (SAs) to enhance their bioavailability. The stability of MOFs during modification with SA solutions is studied. Based on data from powder X-ray diffraction and IR spectroscopy, the optimal MOF–SA pairs are identified. The adsorption and desorption dynamics of cationic (methylene blue) and anionic dyes (methyl orange) by the most promising composites are investigated. The obtained results and proposed patterns can be further used for loading active components, such as phytohormones, into MOF pores, considering the specifics of electrostatic interactions and potential binding via functional groups.
期刊介绍：
Nanobiotechnology Reports publishes interdisciplinary research articles on fundamental aspects of the structure and properties of nanoscale objects and nanomaterials, polymeric and bioorganic molecules, and supramolecular and biohybrid complexes, as well as articles that discuss technologies for their preparation and processing, and practical implementation of products, devices, and nature-like systems based on them. The journal publishes original articles and reviews that meet the highest scientific quality standards in the following areas of science and technology studies: self-organizing structures and nanoassemblies; nanostructures, including nanotubes; functional and structural nanomaterials; polymeric, bioorganic, and hybrid nanomaterials; devices and products based on nanomaterials and nanotechnology; nanobiology and genetics, and omics technologies; nanobiomedicine and nanopharmaceutics; nanoelectronics and neuromorphic computing systems; neurocognitive systems and technologies; nanophotonics; natural science methods in a study of cultural heritage items; metrology, standardization, and monitoring in nanotechnology.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
