Talanta Open最新文献

Eco-friendly molecularly imprinted polymer-based sensing platforms towards pharmaceuticals: recent advances and future prospects

IF 4.1

Talanta Open Pub Date : 2025-03-29 DOI: 10.1016/j.talo.2025.100446

Rüstem Keçili , Ghazanfar Hussain , Chaudhery Mustansar Hussain , Adil Denizli

引用次数: 0

Sensitive and selective detection of cancer biomarkers with molecularly imprinted biosensors

IF 4.1

Talanta Open Pub Date : 2025-03-25 DOI: 10.1016/j.talo.2025.100444

Sibel Büyüktiryaki

引用次数: 0

Emerging Trends in Fluorescent and Quenching Nanomaterials for Viral detection: Innovations in Biological and Chemical sensing

IF 4.1

Talanta Open Pub Date : 2025-03-25 DOI: 10.1016/j.talo.2025.100430

Deeksha Nautiyal, Utkarsh Jain

{"title":"Emerging Trends in Fluorescent and Quenching Nanomaterials for Viral detection: Innovations in Biological and Chemical sensing","authors":"Deeksha Nautiyal, Utkarsh Jain","doi":"10.1016/j.talo.2025.100430","DOIUrl":"10.1016/j.talo.2025.100430","url":null,"abstract":"<div><div>Optical biosensors doped with nanomaterials are the most technologically advanced in viral diagnostics, showing higher sensitivity, specificity, and speed of detection. This review describes the role of fluorescent and quenching nanomaterials in the development of optical biosensing techniques. These sensors enable real-time, non-invasive viral detection with minimal preparation of samples by exploiting unique optical properties of nanomaterials, such as increased fluorescence, efficient energy transfer, and significant signal amplification. It is worth noting that the material's application in point-of-care settings effectively bridges laboratory accuracy with the practical applicability of real-world applications. Moreover, these aspects were put into review, along with the latest advancements in the emerging dual-functional nanocomposites able to integrate the fluorescence and quenching mechanisms for multimodal detection, with emphasis on what has been recently achieved and how these efforts have been developed to tackle stability, reproducibility, and scalability concerns. This will enable optical biosensing through advances in nanotechnology and pave the way for designing next-generation diagnostic platforms capable of addressing current and emerging viral threats.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"11 ","pages":"Article 100430"},"PeriodicalIF":4.1,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143704833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Scotch tape method like modification of electrode stickers: Bismuth-modified copper-based paper device for simultaneous electrochemical detection of Pb(II) and Cd(II)

IF 4.1

Talanta Open Pub Date : 2025-03-25 DOI: 10.1016/j.talo.2025.100442

Rashmi M, Samrat Devaramani

{"title":"Scotch tape method like modification of electrode stickers: Bismuth-modified copper-based paper device for simultaneous electrochemical detection of Pb(II) and Cd(II)","authors":"Rashmi M, Samrat Devaramani","doi":"10.1016/j.talo.2025.100442","DOIUrl":"10.1016/j.talo.2025.100442","url":null,"abstract":"<div><div>Herein we report a simple one-step strategy for surface modification of copper electrode stickers for the fabrication of copper-based paper electrochemical sensing device (Cu-PESD). Taking advantage of conducting adhesive on the copper tape, the scotch tape method is adopted to modify the adhesive surface. Pristine copper electrode stickers fabricated PESD can sense trace metal ions, but the modification of electrodes further improved sensitivity for simultaneous electroanalysis. Bi is selected as a modifier to demonstrate the simple scotch-tape modification strategy. The modified copper electrode stickers with Bi enabled the device to achieve peak resolution, sensitivity, and simultaneous electrochemical detection of Pb(II) and Cd(II). The bismuth-modified copper-based PESD (Bi-Cu-PESD) exhibited the linear range from 0.2 to 12 mg <em>L</em><sup>−1</sup> for simultaneous detection of Pb(II) and Cd(II) ions. The limit of detection was 0.078 mg <em>L</em><sup>−1</sup> and 0.183 mg <em>L</em><sup>−1</sup> for Pb(II) and Cd(II) respectively. Modified electrode stickers were characterized to study the electrode crystallinity, surface morphology, and elemental composition using XRD, SEM, and EDS respectively. The potential of the fabricated PESD was tested by quantifying Pb(II) and Cd(II) ions in the water samples. The electrochemical results were in agreement with the standard AAS method.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"11 ","pages":"Article 100442"},"PeriodicalIF":4.1,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143760427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

3D-printed electrochemical sensor based on graphite-alumina composites: A sensitive and reusable platform for self-sampling and detection of 2,4,6-trinitrotoluene residues in environmental and forensic applications

IF 4.1

Talanta Open Pub Date : 2025-03-24 DOI: 10.1016/j.talo.2025.100441

Raíssa R.D. Brum , Lucas V. de Faria , Natalia M. Caldas , Robson P. Pereira , Diego A. Peixoto , Samuel C. Silva , Edson Nossol , Felipe S. Semaan , Wagner F. Pacheco , Diego P. Rocha , Rafael M. Dornellas

{"title":"3D-printed electrochemical sensor based on graphite-alumina composites: A sensitive and reusable platform for self-sampling and detection of 2,4,6-trinitrotoluene residues in environmental and forensic applications","authors":"Raíssa R.D. Brum , Lucas V. de Faria , Natalia M. Caldas , Robson P. Pereira , Diego A. Peixoto , Samuel C. Silva , Edson Nossol , Felipe S. Semaan , Wagner F. Pacheco , Diego P. Rocha , Rafael M. Dornellas","doi":"10.1016/j.talo.2025.100441","DOIUrl":"10.1016/j.talo.2025.100441","url":null,"abstract":"<div><div>The detection of explosives is of great importance in the forensic scenario. For this reason, we proposed a lab-made graphite/alumina/polylactic acid (G/Al<sub>2</sub>O<sub>3</sub>/PLA)-based 3D-printed electrode for 2,4,6-trinitrotoluene (TNT) electrochemical determination. The material was characterized by infrared and Raman spectroscopy, scanning electron microscopy, and energy dispersion X-ray spectra, indicating that G and Al<sub>2</sub>O<sub>3</sub> were incorporated into the PLA matrix. The proposed electrode combined with the square wave voltammetry (SWV) technique, demonstrated the ability to detect TNT residues, where the first reduction process around -0.24 V was monitored for the analyses. The developed electrochemical strategy supplied a linear range between 0.5 – 6.0 µmol L<sup>-1</sup> and a detection limit of 0.071 µmol L<sup>-1</sup>. The method's applicability was tested on real samples of tap, lagoon, and seawater by direct analysis. Recovery values in the 100 to 106% range were obtained, representing adequate accuracy. The lab-made electrode was also utilized as a sampler to collect TNT residues on different surfaces, enabling the detection of TNT levels in the nanogram range and demonstrating the electrode's exceptional ability to detect trace amounts of the compound. These results reinforce the device's potential as a viable alternative for fast, accurate, and low-cost analysis in practical situations.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"11 ","pages":"Article 100441"},"PeriodicalIF":4.1,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143761149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Castor oil-based molecularly imprinted nanoparticles for the detection of cardiac troponin I: Towards green molecularly imprinted nanoreceptors

IF 4.1

Talanta Open Pub Date : 2025-03-22 DOI: 10.1016/j.talo.2025.100439

Pinar Cakir Hatir , Alice Marinangeli , Alessandra Maria Bossi , Gokhan Cayli

{"title":"Castor oil-based molecularly imprinted nanoparticles for the detection of cardiac troponin I: Towards green molecularly imprinted nanoreceptors","authors":"Pinar Cakir Hatir , Alice Marinangeli , Alessandra Maria Bossi , Gokhan Cayli","doi":"10.1016/j.talo.2025.100439","DOIUrl":"10.1016/j.talo.2025.100439","url":null,"abstract":"<div><div>Molecularly imprinted polymers (MIPs) are synthetic materials that selectively recognize target molecules, offering cost-effective and stable alternatives to antibodies. While MIP nanoparticles are ideal for biomedical applications for their high surface area and their biomolecule-compatible size, traditional monomers used in their synthesis can pose issues in biocompatibility. This study presents a sustainable approach to MIP nanoparticle production using acrylated methyl ricinoleate (AMR), a functional monomer derived from castor oil. These \"GreenNanoMIPs\" were designed to recognize cardiac troponin I (cTnI), a key biomarker for cardiovascular events. The nanoparticles, with an average size of 81 nm, exhibited exceptional homogeneity in suspension, with a low PDI value of 0.064, and outstanding stability, as no changes in particle size distribution or PDI were observed even after one year. GreenNanoMIPs did recognize the entire cTnI protein thorough the epitope approach. Furthermore, GreenNanoMIPs were successfully used for the detection of the cTnI biomarker directly in serum. The study highlights the potential of eco-friendly, biocompatible MIPs for applications in diagnostics, drug delivery, and environmental sensing.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"11 ","pages":"Article 100439"},"PeriodicalIF":4.1,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143715735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Argon versus helium as carrier gas for LA-ICP-MS impurity mapping on ice cores

IF 4.1

Talanta Open Pub Date : 2025-03-21 DOI: 10.1016/j.talo.2025.100437

Pascal Bohleber , Kristina Mervič , Remi Dallmayr , Ciprian Stremtan , Martin Šala

{"title":"Argon versus helium as carrier gas for LA-ICP-MS impurity mapping on ice cores","authors":"Pascal Bohleber , Kristina Mervič , Remi Dallmayr , Ciprian Stremtan , Martin Šala","doi":"10.1016/j.talo.2025.100437","DOIUrl":"10.1016/j.talo.2025.100437","url":null,"abstract":"<div><div>Impurity records in polar ice cores have provided invaluable insights into atmospheric aerosol concentrations of the past environment. The investigation of the oldest, deepest and highly thinned ice core layers is one of the most pressing tasks in today’s state-of-the-art ice core research. This calls for impurity analysis at high spatial resolution, which has to take into account post-depositional processes through the interaction of impurities with the ice matrix. To this end, mapping the impurity distribution in ice with laser ablation inductively-coupled plasma mass spectrometry (LA-ICP-MS) has great potential. Here we explore to what extent the use of Ar as a carrier gas has merits in ice core impurity mapping with LA-ICP-MS. This is motivated by the fact that a) the use of Ar is more economical over He, especially when used in conjunction with large volume sample cells, and b) an increase in sensitivity has previously been reported when adding ”wet” Ar to He as a carrier gas. We show that, albeit not fully matching the single-pulse-performance of He, it is possible to achieve mapping at up to 500 Hz with Ar in a system that is originally designed for He. In contrast to what we find on NIST glass standards and a sample of decorative murrina glass, maps obtained on ice core samples show higher intensities in Ar than in He. In an extreme case example, we show how Ar may permit to obtain signals in a deep interglacial ice sample from Antarctica with very low impurity concentrations, which was not possible when using He with the same LA-ICP-MS system.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"11 ","pages":"Article 100437"},"PeriodicalIF":4.1,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143704830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Selective dual-mode detection of doxycycline using orange carbon dots/calcium-murexide composite system: From spectroscopic analysis to smartphone-based sensing

IF 4.1

Talanta Open Pub Date : 2025-03-20 DOI: 10.1016/j.talo.2025.100438

Fatma A.M. Abdel-aal , Ashraf M. Mahmoud , Azza H. Rageh , Mohamed R. Elmasry , Yousef A. Bin Jardan , Mohamed M. El-Wekil , Al-Montaser Bellah H. Ali

{"title":"Selective dual-mode detection of doxycycline using orange carbon dots/calcium-murexide composite system: From spectroscopic analysis to smartphone-based sensing","authors":"Fatma A.M. Abdel-aal , Ashraf M. Mahmoud , Azza H. Rageh , Mohamed R. Elmasry , Yousef A. Bin Jardan , Mohamed M. El-Wekil , Al-Montaser Bellah H. Ali","doi":"10.1016/j.talo.2025.100438","DOIUrl":"10.1016/j.talo.2025.100438","url":null,"abstract":"<div><div>A novel and selective analytical method has been developed for doxycycline (DOX) determination, addressing the critical need for monitoring this widely used antibiotic in environmental samples. The method employs a hybrid sensing system combining orange-emitting carbon dots (O-CDs) with a calcium-murexide (Ca@Mu) complex, offering a unique dual-mode detection approach. Unlike conventional methods that rely on direct fluorescence quenching by DOX, which often suffer from poor selectivity, this system utilizes the competitive binding between DOX and murexide for Ca<sup>2+</sup> ions. Initially, the pink-colored Ca@Mu complex formed under alkaline conditions causes fluorescence quenching of O-CDs at 552 nm. Upon introduction of DOX, its stronger Ca<sup>2+</sup>-binding affinity leads to the formation of a calcium-DOX complex, liberating free Mu and triggering both colorimetric (pink to orange) and fluorometric (restoration of O-CDs emission) responses. Comprehensive characterization and mechanistic investigations employing different spectroscopic techniques confirmed the sensing mechanism. The method demonstrates excellent selectivity for DOX among other tetracyclines and potential interferents, along with impressive analytical performance including good linearity (1.0-35.0 μM), low detection limit (325 nM), and high precision. Additionally, a smartphone-based colorimetric platform was developed for convenient on-site analysis. The practical utility of this method was validated through successful determination of DOX in environmental water samples with excellent recovery rates, offering a reliable and user-friendly approach for environmental monitoring of this important antibiotic.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"11 ","pages":"Article 100438"},"PeriodicalIF":4.1,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143704832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigating the acetone sensing capabilities of metal-organic framework-derived SnO2/ZnO nanocomposite

IF 4.1

Talanta Open Pub Date : 2025-03-20 DOI: 10.1016/j.talo.2025.100435

M. Navaneethakannan , J. Jayachandiran , C. Venkateswaran , D. Nedumaran

{"title":"Investigating the acetone sensing capabilities of metal-organic framework-derived SnO2/ZnO nanocomposite","authors":"M. Navaneethakannan , J. Jayachandiran , C. Venkateswaran , D. Nedumaran","doi":"10.1016/j.talo.2025.100435","DOIUrl":"10.1016/j.talo.2025.100435","url":null,"abstract":"<div><div>Recent advancements in the quantification of gas molecules in human breath have opened new avenues for diagnosing diseases like diabetes and cancer. These gas molecules act as biomarkers for specific diseases reflecting changes in metabolism caused by diseased cells. Acetone, in particular, is recognized as a potential biomarker for both diabetes and cancer. However, the existing acetone sensors suffer from low sensitivity, long response and recovery times, high cost, and high-power consumption owing to the factors like material property, sensing mechanism and operational conditions. This study explored the benefits of metal-organic frameworks (MOFs), including high surface area, porosity, structural tunability, and diverse signal transduction capabilities. The MOF-derived SnO<sub>2</sub>/ZnO nanocomposite was synthesized and analysed the material properties using TGA, XRD, FTIR, SEM/EDAX, HR-TEM, and XPS. These analyses confirmed the formation of the SnO<sub>2</sub>/ZnO nanocomposite with a uniform surface morphology and an average crystalline size of 14.4 nm. The sensing material was then coated by e-beam evaporation onto Cr/Au interdigitated electrode (IDE) fabricated via photolithography and a bi-layer lift-off process. The fabricated sensor demonstrated enhanced electrical conductivity at higher operating temperatures, attributed to the presence of n-n heterojunctions in the material. Notably, the sensor exhibited a remarkable response of 81.88 % towards 10 ppm of acetone at 250 °C, with excellent selectivity over other gases and a detection limit of 600 ppb. Additionally, the sensor showed a rapid response/recovery time of 17/19 s to acetone molecules. These results confirm the sensor's ability to detect and quantifying acetone molecules from human breath.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"11 ","pages":"Article 100435"},"PeriodicalIF":4.1,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143725880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Geographic determination of Pinus ponderosa using DART TOFMS, ICP-MS, and LIBS handheld analyzer

IF 4.1

Talanta Open Pub Date : 2025-03-19 DOI: 10.1016/j.talo.2025.100440

Erin R. Price , Kierra R. Cano , Caelin P. Celani , Helder V. Carneiro , Karl S. Booksh , James A. Jordan , Pamela J. McClure , Megahn H. Pinedo , Michael E. Ketterer , Kent M. Elliott , Tyler B. Coplen , Edgard O. Espinoza

{"title":"Geographic determination of Pinus ponderosa using DART TOFMS, ICP-MS, and LIBS handheld analyzer","authors":"Erin R. Price , Kierra R. Cano , Caelin P. Celani , Helder V. Carneiro , Karl S. Booksh , James A. Jordan , Pamela J. McClure , Megahn H. Pinedo , Michael E. Ketterer , Kent M. Elliott , Tyler B. Coplen , Edgard O. Espinoza","doi":"10.1016/j.talo.2025.100440","DOIUrl":"10.1016/j.talo.2025.100440","url":null,"abstract":"<div><div>Due to legal requirements on international imports, it is important for law enforcement and regulatory agencies to identify the geographical provenance of timber. Current methods for geographic identification utilize data generated by direct analysis in real time time-of-flight mass spectrometry (DART TOFMS), genetics, and isotope-ratio mass spectrometry (IRMS), but identification methods based on genetics and IRMS data require months to years to create usable databases. This study used machine learning algorithms to compare the results of DART TOFMS, inductively coupled plasma mass spectrometry (ICP-MS), and a handheld laser-induced breakdown spectroscopy (LIBS) analyzer for use in geographic identification of five populations of <em>Pinus ponderosa</em> spaced between 14 to 72 km apart. The results of the study showed comparable performances from machine learning algorithms applied to the ICP-MS and LIBS data with accuracy and kappa values over 90% while the DART TOFMS had an accuracy of 76% and a kappa value of 70%. This study demonstrated that data from the LIBS handheld analyzer is a viable and intriguing alternative to ICP-MS and DART TOFMS analyses in generating training databases and further indicates that trace elemental analysis via ICP-MS is a promising method for generating databases used to identify the origin of timber.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"11 ","pages":"Article 100440"},"PeriodicalIF":4.1,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143715696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0