Talanta Open最新文献

{"title":"Development of engineered Zn-MOF/g-C3N4 based photoelectrochemical system for real-time sensors and removal of naproxen in wastewater","authors":"Abera D. Ambaye ,&nbsp;Sithembela A. Zikalala ,&nbsp;Karabo C. Mashiloane ,&nbsp;Jemal F. Nure ,&nbsp;Mesfin A. Kebede ,&nbsp;Touhami Mokrani ,&nbsp;Edward N. Nxumalo","doi":"10.1016/j.talo.2024.100371","DOIUrl":"10.1016/j.talo.2024.100371","url":null,"abstract":"<div><div>Naproxen-contaminated water may lead to the accumulation of the drug in aquatic organisms and can pose high risks to an aquatic environment and human beings. Therefore, this work aimed to develop photoelectrochemical sensing and degradation of naproxen (NPX) using zinc-metal organic framework /graphitic carbon nitride thin film-based fluorine-doped tin oxide (Zn-MOF/g-C₃N₄/FTO) as anode material for the sensing and degradation of naproxen (NPX). The surface morphology, structure, surface property, surface area, optical property, photocurrent, and charge transfer kinetics abilities were studied using different techniques. The nanocomposites showed a superior photocurrent response (0.815 mA cm^-2) compared to the original g-C₃N₄ (0.328 mA cm^-2). The photo-anode made of Zn-MOF@g-C₃N₄/FTO displayed the highest photocurrent value, indicating that the alignment of the two semiconductor bands prevented the quick recombination of electron-hole pairs. Owing to these attractive features, the Zn-MOF/g-C₃N₄/FTO electrode was applied for photoelectrochemical detection of NPX using chronoamperometry. Interestingly, the nanocomposites-based FTO ascribed a lower detection limit (2.3 ng <span>l</span>^-1) with a wide linear range concentration of NPX (0.5 to 200 µg <span>l</span>^-1). Additionally, the analytical assessment of repeatability and reproducibility demonstrated robust performance, with commendable relative standard deviations (RSD%) of 2.54 % and 2.40 %, respectively. On the other hand, a remarkable degradation efficiency of 97.52 % was attained when employing a bias potential of 0.1 V during a 2 h photoelectrocatalytic oxidation of NPX. The degradation process was primarily driven by the active participation of holes and hydroxyl radicals in ring opening and subsequent cleavage of by-products. The notable effectiveness of this degradation can be attributed to the combined and synergistic effects of both electrochemical and photocatalytic degradation techniques. The current state demonstrates its effectiveness in the photoelectrochemical sensing and removal of NPX using MOF/g-C₃N₄ nanocomposites-based electrode materials in wastewater.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"10 ","pages":"Article 100371"},"PeriodicalIF":4.1,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142662698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Continuous-flow analysis of nitrogen compounds in environmental water using a copper–zinc reduction coil","authors":"Satoshi Morikubo ,&nbsp;Nodoka Takahashi ,&nbsp;Yorihiro Kumazawa ,&nbsp;Yasuhiko Takuma ,&nbsp;Daisuke Enomoto ,&nbsp;Takashi Nishimura ,&nbsp;Ryosei Kanno ,&nbsp;Suguru Okunishi ,&nbsp;Hiroto Maeda","doi":"10.1016/j.talo.2024.100378","DOIUrl":"10.1016/j.talo.2024.100378","url":null,"abstract":"<div><div>The copper–cadmium reduction method has been applied to determine nitrogen compounds in heavily contaminated environmental water. However, there is an international demand to reduce the use of cadmium because it is harmful to humans and environment. Hence, a copper–zinc reduction continuous flow analysis system without using cadmium was developed for nitrogen-compound determination. However, the effects of seawater contaminants on this analytical method remains unknown. Therefore, in this study, the effects of contaminants on the developed method are investigated, and the applicability of the method to environmental water analysis is examined. Resultantly, interference due to magnesium precipitation is confirmed; however, this could be prevented by adjusting the concentration of the analytical reagent, i.e.,. ethylenediaminetetraacetic acid disodium. The measurement of certified reference materials under the new conditions, with precipitation countermeasures, show good results, with an accuracy of over 96 %. Additionally, a recovery study using actual environmental water afforded good results, with recovery of &gt;95 % for all samples. These results indicate that the proposed method is an excellent, cadmium-free analytical method capable of analyzing environmental water as effectively as conventional methods.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"10 ","pages":"Article 100378"},"PeriodicalIF":4.1,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142662613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing isomer specificity in mass spectrometry by combining silver ion adduction and ion mobility","authors":"Varun V. Sharma ,&nbsp;Danjo De Chavez ,&nbsp;Susan E. Slade ,&nbsp;Ingela Lanekoff","doi":"10.1016/j.talo.2024.100373","DOIUrl":"10.1016/j.talo.2024.100373","url":null,"abstract":"<div><h3>Background</h3><div>Identification and characterization of steroids from complex mixtures with isomeric precision is key to studying endocrine-related metabolism and disorders. Whereas the golden standard chromatography, including liquid chromatography and gas chromatography, can be coupled with mass spectrometry to separate steroids prior to ionization, this separation is time-consuming. Contrarily, direct infusion techniques can offer increased throughput; however, these are often hampered by limited structural specificity. Thus, it is important to develop new analytical tools for direct infusion mass spectrometry that will provide isomeric specificity.</div></div><div><h3>Results</h3><div>Herein, we show that direct infusion with electrospray ionization in combination with silver adduction and cyclic ion mobility mass spectrometry (cIMS) enables mobility separation and improves the detectability of steroid isomers. Specifically, silver ion adduction of steroids increases instrumental response up to 14 times and enables almost baseline mobility separation of closely related structural steroid isomers even at low cIMS resolution. By combining experimental and theoretical data, we show that the silver interacts with the steroid isomer at single or multiple sites, which introduces conformational changes that enable mobility separation. Moreover, we show that the combination of cIMS and silver adduct fragmentation in tandem mass spectrometry provides an additional dimension for annotation of steroid isomers. Thus, the simple introduction of silver ions into the electrospray solvent provides a great gain in the analytical discernment of steroid isomers.</div></div><div><h3>Significance</h3><div>For the first time, we show that the use of silver adduction introduces a conformational change in steroids that allows for them to be separated with low-resolution ion mobility spectrometry without any prior derivatization, chromatographic separation, or instrumental modification. This is a new and important tool for analyzing steroid isomers that can unravel their importance in biological systems.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"10 ","pages":"Article 100373"},"PeriodicalIF":4.1,"publicationDate":"2024-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142662699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metal organic frameworks for bacterial detection in environmental samples","authors":"Hadeer M. Bedair ,&nbsp;Alaa Bedair ,&nbsp;Mahmoud Hamed ,&nbsp;Marcello Locatelli ,&nbsp;Fotouh R. Mansour","doi":"10.1016/j.talo.2024.100374","DOIUrl":"10.1016/j.talo.2024.100374","url":null,"abstract":"<div><div>Pathogenic bacteria pose significant threats to public health. Early and accurate detection of bacteria is crucial for infection control and prevention of outbreaks. This paper reviews recent advances in metal organic framework (MOF)-based methods for bacterial detection. MOFs are promising materials for biosensing due to their large surface areas, customizable properties, and ability to integrate various sensing capabilities. Several colorimetric and electrochemical detection techniques that utilize MOFs are discussed. Colorimetric assays combining MOFs with gold nanoparticles, peroxidase-mimicking activity, and aptamer recognition have achieved sensitive and specific detection of bacteria such as <em>E. coli</em> and <em>S. aureus</em>. Electrochemical biosensors integrating MOFs, antibodies, aptamers and quantum dots have also demonstrated low detection limits for various bacteria. Notably, techniques using MOF peroxidase-like activity coupled with magnetic separation or competitive binding assays show potential for point-of-care pathogen detection. Furthermore, optimization of MOF properties and integration within microfluidic platforms may lead to portable, low-cost and rapid methods suitable for on-site bacterial analysis in diverse settings. Continued exploration of MOF-based sensing strategies holds promise for improved bacteria monitoring and control of infectious diseases.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"10 ","pages":"Article 100374"},"PeriodicalIF":4.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142662612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Facile electrostatic incorporation of the food dye, Dianthine B, for an ultrasensitive tracking and quantification of fexofenadine drug employing an ''on-on++ fluorescence'' strategy","authors":"Ahmed Abdulhafez Hamad ,&nbsp;Afnan S. Batubara","doi":"10.1016/j.talo.2023.100217","DOIUrl":"https://doi.org/10.1016/j.talo.2023.100217","url":null,"abstract":"<div><p>This research presents a facile spectrofluorimetric technique for detecting fexofenadine (FXD) drug based on the idea of Dianthine B's Resonance Rayleigh Scattering response augmentation. A food dye, Dianthine B (DB), is a fluoresine base-structured pigment used as a food additive, flavor, bio-stainer, and for a medicational prognosis purpose. Interest in employing food additives for tagging and tracking has increased because of their safety, elevated quantum outputs, and propensity to biomaterials labeling. The planned method validated and evaluated the target drug quickly and efficiently using a direct, facile, simple, and single-pot-single-step spectrofluorimetric approach, making it more favorable to the environment. Facile coupling between FXD and Dianthine B occurred rapidly in an acidic environment. A correlation was established between the increased responsiveness of the food dye to Resonance Rayleigh Scattering signals as a result of FXD and the molecular size of the coupled product formed at 361 nm. The linear range was determined to be from 50 to 1500 ng mL⁻¹, while the sensitivity limits were 15 ng mL⁻¹ for LOD and 46 ng mL⁻¹ for LOQ. Analyte-dye coupled products were studied to establish the optimal settings for the system's tunable variables. Additionally, there were no problems with the system meeting the International Council for harmonisation ICH requirements. Plus, enough of the material was retrieved for medicinal applications. The coupled product's quantum yield was evaluated. Additionally, the environmental evaluation of the proposed system was done using ecological metrics, including an eco-scale (95/100), the National Environmental Methods Index, NEMI (full green pictograms), the Green Analytical Procedure Index (GAPI), and the Analytical GREEnness Measure, AGREE (0.8/1). These results indicated that the planned method's significant level of greenness was achieved.</p></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"7 ","pages":"Article 100217"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"3451922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel bulk optode for ultra-trace detection of antimony coupled with spectrophotometry in food and environmental samples","authors":"Islam M.I. Moustafa ,&nbsp;Alaa S. Amin ,&nbsp;Eman Darwish","doi":"10.1016/j.talo.2023.100197","DOIUrl":"https://doi.org/10.1016/j.talo.2023.100197","url":null,"abstract":"<div><p>A novel bulk optode was modified for ultra-trace detection of antimony. The optode was synthesized by incorporating fabricated ionophore, 6-{4-(2,4-di-hydroxyphenyl)diazenyl)phenyl}-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbo-nitrile (DDPODC), 3-octadecanoylimino-7-(diethyl‑amino)-1,2-benzophenoxa-zine (ETH5294) as a chromoionophore, sodium tetraphenyl borate (NaTPB) as an anionic additive, and dioctyladipate (DOA) as a plasticizer in a poly vinyl chloride (PVC) membrane. In determining Sb³⁺, various parameters were implemented. Spectrophotometric procedure (λ_max of 661 nm) was applied to define Sb³⁺ within optimal conditions. The optode has a wide range of 2.5 × 10⁻⁸ to 4.0 × 10⁻⁵ M Sb³⁺ with the detection and quantification limits as low as 7.0 × 10⁻⁹ and 2.4 × 10⁻⁸ M, respectively. The response time of optode was 3.0 min, with a RSD% of 1.75% (for 2.0 × 10⁻⁵ M, <em>n</em>=6). A 0.15 M HCl solution could be used to regenerate the optode. The interfering ions were studied. It was revealed that the optode was highly selective to Sb³⁺ ions and had no significant response to common cations and anions. It can be appealed that the optode can specifically detect Sb³⁺ ions. The optode was favorable applied to assess total antimony ions after reduction of Sb⁵⁺ to Sb³⁺ using potassium iodide and ascorbic acid as reducing agents in various water, food and biological samples.</p></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"7 ","pages":"Article 100197"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"1821925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Screening analysis: An alternative for real-time analysis and greener microwave-assisted persulfate decomposition of flavored beverages","authors":"Rodolfo M.M. Santana ,&nbsp;Lidio Pereira Junior ,&nbsp;Marcos Diogo S. Pereira ,&nbsp;Mauro Korn","doi":"10.1016/j.talo.2023.100229","DOIUrl":"https://doi.org/10.1016/j.talo.2023.100229","url":null,"abstract":"<div><p>The proposed procedure aims to generate information about the decomposition efficiency of organic matter before the instrumental determination of elements and real-time decision-making. In the presence of organic compounds samples, the irradiation time was consistently higher (at least 20 s or more) than that observed for the appearance of MnO₄^– in organic matter-free solutions (10±1 s, <em>n</em> = 6). Moreover, RCC values ≤14% were determined for all solutions independent of the target compound observed. Total carbon was determined in samples before and after persulfate decomposition, with a 95% reduction in the carbon content, except for grape-flavored waters (RCC = 85%). The microwave-assisted S₂O₈²⁻/Mn²⁺ system allowed a fast, clean and effortless approach leading to material, energy, and time-saving method for mineralizing beverages.</p></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"7 ","pages":"Article 100229"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"1821929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multielemental analysis of oils and animal fat by using deep eutectic solvents assisted by an aerosol phase extraction procedure","authors":"Ana Torres ,&nbsp;Ismael Romero ,&nbsp;Raquel Sánchez ,&nbsp;Ana Beltrán ,&nbsp;Gabriela Guillena ,&nbsp;José-Luis Todolí","doi":"10.1016/j.talo.2023.100234","DOIUrl":"https://doi.org/10.1016/j.talo.2023.100234","url":null,"abstract":"<div><p>In the present study, thirteen elements (Ag, Al, Ba, Cd, Cr, Cu, Fe, K, Li, Mg, Mn, Ni, Pb) have been extracted from used cooking oils, olive oils and animal fat. Either inductively coupled plasma optical emission spectrometry (ICP-OES) or tandem mass spectrometry (ICP-MS/MS) have been chosen as detection techniques. Due to the difficulty of directly introducing highly viscous organic samples into the spectrometer, a fast dispersive liquid – liquid aerosol phase extraction (DLLAPE) method has been selected to isolate the analytes from the sample matrix. The DLLAPE is based on the generation of an aerosol from the extracting phase with the help of a pneumatic nebulizer. This high velocity aerosol impacts and penetrates in the liquid sample. Consequently, the liquid – liquid exchange surface area becomes high, thus leading to high extraction yields. A hydrophilic deep eutectic solvent (DES) consisting of choline chloride and ethylene glycol (1:2 mass ratio) has been selected as the extracting solvent. Prior to undertaking the experiments, the extraction method has been evaluated in terms of precision under suitable conditions. In comparison with conventional methods based on sample digestion, sample dilution and shot analysis or extraction assisted by vortex agitation, the DLLAPE shows several advantages, because it is faster, and it provides lower limits of detection than the reference methodologies. The procedural limits of quantification for the determined elements with the DLLAPE in ICP-OES were 0.046 (Ag), 0.396 (Al), 0.013 (Cd), 0.033 (Cr), 0.040 (Cu), 0.20 (Fe), 0.026 (K), 0.026 (Li), 0.33 (Mg), 0.013 (Mn), 2.64 (Ni) and 0.53 (Pb) mg kg⁻¹. Meanwhile, pLOQ in ICP-MS/MS lowered by roughly one order of magnitude. The accuracy of the aerosol phase extraction method has been evaluated through the determination of the recoveries for four representative analytes (Ca, Cu, Mg and Ni) from spiked real samples. For these elements, recovery has taken values of (100 ± 20)%. Moreover, a comparison of the multielemental concentration obtained with conventional methods (<em>c.a.</em>, sample dilution and shot ICP analysis and liquid-liquid extraction using a vortex agitator) against that measured with the DLLAPE has been carried out. Multiemelemental concentrations have been obtained for real samples and the found levels have been similar to those encountered in previously published works.</p></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"7 ","pages":"Article 100234"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"1821931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analyzes of β-lactam antibiotics by direct injection of environmental water samples into a functionalized graphene oxide-silica packed capillary extraction column online coupled to liquid chromatography tandem mass spectrometry","authors":"Edvaldo V.S. Maciel ,&nbsp;Deyber A. Vargas-Medina,&nbsp;Fernando M. Lancas","doi":"10.1016/j.talo.2023.100185","DOIUrl":"https://doi.org/10.1016/j.talo.2023.100185","url":null,"abstract":"<div><p>An environmentally friendly and high-throughput method for monitoring β-lactam antibiotics in environmental water samples is presented. In this study, an in-lab synthesized graphene oxide supported onto aminopropyl silica (GO@SiO₂) sorbent was packed inside a fused silica capillary to produce a miniaturized extraction column. The main goal was to develop a greener analytical method that requires low amounts of chemicals to be executed and, consequently, generates a reduced volume of toxic waste. To achieve that, the GO@SiO₂ extraction column was online coupled with a LC-MS/MS instrument to carry out an automated and miniaturized sample preparation step before analytical quantification. A chemometric optimization was performed considering the variables possibly affecting the analytical performance: sample loading flow, sample loading time, and temperature of analysis. Under optimized conditions, the method reported good analysis times (12 min) and consumed fewer reagents compared to other publications on the same topic. Important validation parameters were evaluated accordingly with the ICH Q2(R1) validation guideline. The method showed appropriate linearity between 1 – 100 μg/L (R² &gt; 0.99), as well as LODs (S/<em>N</em> = 3) in the range of 0.2 – 0.3 μg/L. Accuracy, intra- and inter-day precision (RSD%) were in acceptable ranges between 82.3 – 107.1%, and 0.8 – 20.6%, respectively. Out of ten collected environmental water samples, two reported the presence of cefalexin. Ultimately, the method was demonstrated to be fast, environmentally friendly, and reliable for monitoring the β-lactams. Therefore, it represents an excellent alternative to still widely-used and non-miniaturized methods based on time-consuming sample preparation.</p></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"7 ","pages":"Article 100185"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"2643007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Direct determination of chlorine in the glycerin by-product of biodiesel production: A green approach using energy dispersive X-ray fluorescence spectrometry","authors":"Marlin J. Pedrozo-Peñafiel,&nbsp;Adriana Doyle,&nbsp;Andréa S. Vieira,&nbsp;Joseany M.S. Almeida,&nbsp;Ricardo Q. Aucélio","doi":"10.1016/j.talo.2023.100214","DOIUrl":"https://doi.org/10.1016/j.talo.2023.100214","url":null,"abstract":"<div><p>Glycerin, by-product of biodiesel, is produced in large amounts and it contains several contaminants, including chorine (due to the neutralization stage using HCl). When using this glycerin as biomass to produce energy, the presence of alkaline chlorides may lead to the formation of corrosive fumes at high temperatures. In this sense, the knowledge of chloride content is important in order to decide the fate of this raw by-product. The direct spectrometric determination of chlorine is an analytical challenge. In this context, energy-dispersive X-ray fluorescence spectrometry provided direct and accurate determination, relying on external calibration based on sample dilution and matrix matching with mixture of pure glycerin and water and using NaCl as the analytical (primary) standard. Method limit of quantification was 50 mg kg⁻¹, with analytical curve up to 1000 mg kg⁻¹ (R² = 0.9992), and repeatability below 5% were found to be adequate for such application in such highly salty samples (original concentrations at mg g⁻¹). In addition to sample directly analysis, without any previous treatment but homogenization and dilution, not requiring chemical derivatization and the not using of toxic reagents are in consonance to the analytical green chemistry requirements, allowing direct analysis of sample with no chemical derivatization with toxic reagents.</p></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"7 ","pages":"Article 100214"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"1631708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}