Talanta Open最新文献

{"title":"Polypyrrole-based bovine serum albumin imprinted electrochemical sensor for clinical application","authors":"Mona Ebadi ,&nbsp;Saiful Amri Mazlan ,&nbsp;Mohd Aidy Faizal Johari ,&nbsp;Muhammad Rahimi Yusop","doi":"10.1016/j.talo.2025.100510","DOIUrl":"10.1016/j.talo.2025.100510","url":null,"abstract":"<div><div>The molecularly imprinted polymer (MIP), in conjunction with bovine serum albumin (BSA), plays a crucial role in identifying various health conditions, making its monitoring essential for clinical applications. This study aims to fabricate a highly sensitive biosensor based on a molecularly imprinted polymer (MIP) for the detection of a bovine serum albumin (BSA) sensing platform. The MIP was developed using BSA as the template molecule and polypyrrole (PPy) as the functional monomer via an electrochemical polymerisation process induced by cyclic voltammetry (CV) onto screen-printed carbon electrodes (SPCE). Surface morphology analysis confirmed the formation of a polymer nanofilm with surface variations. Electrochemical characterisation of the MIP sensor was carried out via cyclic voltammetry across a BSA concentration range of 10–60 mg.ml^-1. The sensor demonstrated excellent sensitivity, with a limit of detection (LOD) of 0.31 µg.ml^-1. A strong linear response was observed, with a correlation coefficient (R²) exceeding 0.99. The sensor exhibited excellent reproducibility and repeatability, with relative standard deviations (%RSD <em>n</em> = 3) &lt;1 %. The selectivity of the MIP/BSA sensor toward BSA was investigated in the presence of creatinine/urea, and the results revealed the strong recognition ability of the sensor toward the BSA protein. Owing to its reusability, fast response time, and ease of operation, this biosensor holds promise for real-time detection and monitoring of BSA and can potentially be adapted for other clinically relevant proteins.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"12 ","pages":"Article 100510"},"PeriodicalIF":4.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144563170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design and synthesis of 8-nitroquinoline azine D-π-A module chemosensors: Fluorogenic onsite detection of sarin gas mimic- DCP","authors":"Sentamil Selvi Ramasamy ,&nbsp;Kaviyarasu Adhigaman ,&nbsp;Vandana Nandakumar ,&nbsp;Akilesh Muralidharan ,&nbsp;Shankar Ramasamy ,&nbsp;Suresh Thangaraj","doi":"10.1016/j.talo.2025.100508","DOIUrl":"10.1016/j.talo.2025.100508","url":null,"abstract":"<div><div>Organophosphorus (OP) chemical warfare agents are highly toxic and directly interrupts the acetylcholine esterase (AChE) enzyme activity in the central nervous system while exposed to those lethal substances. Detection of OP agents is challenging one and existing analytical methods are also having limitations and tedious operating procedures. In this context, we designed two ICT based 8-nitro substituted quinoline unsymmetrical azine sensors (<strong>NQH</strong> and <strong>NQH-1)</strong> for the detection of sarin mimic diethylchlorophosphate (DCP) nerve agent. The developed sensors are shown significant orange region emissive responses to DCP molecule in “TURN ON” manner with reliable red shifts. The limit of detection for the probes <strong>NQH</strong> and <strong>NQH-1</strong> were in micromolar level found to be 1.5 and 3.2 µM respectively. The consequent mechanistic pathway proposed for the sensing systems are PET combined with ICT for <strong>NQH</strong>, while the <strong>NQH-1</strong> system functions through ESIPT coupled with ICT processes. The proposed mechanistic gateway further elucidated through ¹H NMR, ³¹P NMR titrations in addition to the dynamics of DFT. Notably, the proposed <span>D</span>-π-A module chemosensors have good fluorescent module for instant field level recognition of nerve agents (surrogates). The significance of the research found in the sensing platform has been achieved by the fabrication of cotton swab and paper disc kits for the real time analysis.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"12 ","pages":"Article 100508"},"PeriodicalIF":4.1,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144523084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Graphene oxide and molecularly imprinted polymer-based sensor for the electrochemical detection of benzene: A novel tactic in early diagnosis of lung cancer","authors":"Warren Rosario ,&nbsp;Devesh K. Avasthi ,&nbsp;Nidhi Chauhan","doi":"10.1016/j.talo.2025.100506","DOIUrl":"10.1016/j.talo.2025.100506","url":null,"abstract":"<div><div>Early cancer detection significantly enhances survival rates, making widespread diagnostic screening essential. However, the high cost and limited accessibility of diagnostic tools pose major challenges. Nanomaterial-based sensors offer a promising solution due to their portability, user-friendly design, and cost-effective manufacturing. Volatile organic compounds (VOCs) emitted by the human body are closely linked to the presence of life-threatening diseases, with benzene emerging as a significant biomarker in the breath and blood of individuals at risk of developing lung cancer. Leveraging this correlation, we have developed a sensor capable of detecting benzene with high reliability. This study details the fabrication of an electrochemical sensor on a screen-printed electrode (SPE), modified with graphene oxide (GO) followed by molecularly imprinted polymer (MIP). SPE promotes the development of a miniaturized and user-friendly sensing platform. The incorporation of GO is responsible for improving the sensor's response due to its excellent electrochemical properties. The MIP is synthesized using benzene as a template, which creates imprints of benzene on the polymer. Integration of this MIP significantly improves the sensor’s selectivity. This approach addresses the key limitation of low selectivity in VOC sensors for medical applications. The sensor demonstrated a broad linear range of 0.1–1000 ppb with a sensitivity of 15.5 µA/ppb and exhibited excellent selectivity toward benzene. By enhancing both sensitivity and selectivity, the developed sensor offers a promising solution toward effective, accessible, and early lung cancer diagnosis.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"12 ","pages":"Article 100506"},"PeriodicalIF":4.1,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144549660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecularly imprinted polymer-based sensors: Design and advances in the analysis of DNA and protein","authors":"Arzum Erdem,&nbsp;Huseyin Senturk,&nbsp;Mehmet Karakus","doi":"10.1016/j.talo.2025.100507","DOIUrl":"10.1016/j.talo.2025.100507","url":null,"abstract":"<div><div>Molecularly imprinted polymers (MIPs) have emerged in recent years as highly promising materials for sensor design, owing to their high selectivity, stability, and reusability toward target analytes. This review specifically focuses on MIP-based sensor applications aimed at detecting critically important biomolecules such as proteins and DNA, which play essential roles especially in the biomedical field. Although antibody-based immunoassays for protein detection and PCR-based methods for DNA analysis provide high specificity and sensitivity, these conventional approaches have significant limitations, including high costs, limited stability, complex instrumentation, and the necessity of highly skilled personnel. MIPs have recently gained attention as synthetic recognition elements capable of overcoming these limitations. The rationale behind jointly addressing protein and DNA analysis lies primarily in the shared challenges presented by these biomolecules, such as molecular size, structural complexity, and specificity of binding. Furthermore, similar analytical approaches and transduction mechanisms employed in the sensor designs for these two groups allow for a more comprehensive and integrated evaluation. This review thoroughly examines MIP structures integrated into electrochemical, optical, quartz crystal microbalance (QCM), and other sensor platforms. Current limitations such as heterogeneity of binding sites and incomplete removal of template molecules are critically discussed, alongside proposed solutions like incorporation of nanomaterials, computational modeling, and novel polymerization strategies. In conclusion, this review provides an extensive evaluation of recent advances in protein and DNA detection using MIP-based sensors, clearly outlining the current state, encountered challenges, and future perspectives within the field.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"12 ","pages":"Article 100507"},"PeriodicalIF":4.1,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144549661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"3D printed hardware for automation of proteomics sample preparation at the Meso-Scale","authors":"Sadie R. Schultz ,&nbsp;Matthew M. Champion","doi":"10.1016/j.talo.2025.100505","DOIUrl":"10.1016/j.talo.2025.100505","url":null,"abstract":"<div><div>Mass spectrometry-based proteomics is the dominant method for measuring peptides and proteins from complex mixtures. In bottom-up approaches, proteins are digested or proteolyzed prior to LC-MS/MS analysis. Peptides are fragmented, and proteins are inferred <em>via</em> peptide spectral matching (PSM). The throughput of this process is surprisingly low; a proteomics core facility might analyse &lt;20 samples/day per instrument using UHPLC-MS/MS. Because of this, automation in proteomics is rare, and virtually all preparation is performed by hand. We developed 3D printed hardware and automated sample preparation modules for a lower-cost Andrew Alliance pipetting robot. The robot operates on simple principles, using traditional pipettes and follows protocols closely resembling manual preparation. Here, we present modular protocols for the major techniques in proteomics preparation: in-solution and S-Trap digestion; Tip and solid-phase extraction (SPE) based desalting. Both approaches yield dense protein identifications from complex proteomes. Automated samples had high reproducibility: ∼60 % of proteins identified from in-solution and S-Trap digested samples had a measured CV of ≤20 %. In contrast, 52 % of in-solution digested and 63 % of S-Trap digested of proteins identified from manually prepared samples had CVs ≤20 %. Automated sample digestion and tip-based desalting had reduced ≅ 70 % and 40 % quantitative yield respectively compared to manual preparation according to the protein label-free quantification (LFQ). Increasing injection amount to normalize the yield restored protein and peptide identifications which demonstrates the differences between manual and automated methods were predominantly due to reduced recovery. Overall, automation of bottom-up proteomics sample preparation at the meso‑scale offers increased reproducibility in non sample-limited applications.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"12 ","pages":"Article 100505"},"PeriodicalIF":4.1,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144480821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of atmospheric pressure DBD plasma treatment on the biodegradability, hydrophilicity, and mechanical properties of PVA/PEG/Chitosan/HA nanofibers for bone tissue engineering","authors":"Hartatiek ,&nbsp;M.I. Wuriantika ,&nbsp;Yudyanto ,&nbsp;A. Taufiq ,&nbsp;M. Diantoro ,&nbsp;Y. Yusuf ,&nbsp;M. Taufik ,&nbsp;J.F. Fatriansyah","doi":"10.1016/j.talo.2025.100501","DOIUrl":"10.1016/j.talo.2025.100501","url":null,"abstract":"<div><div>The effectiveness of scaffolds in supporting bone tissue regeneration is highly dependent on surface modification. Atmospheric pressure dielectric barrier (DBD) plasma treatment offers a practical method that offers simplicity, time efficiency, cost effectiveness, and reliable results. In this study, nanofiber scaffolds composed of PVA, PEG, chitosan, and hydroxyapatite were fabricated using electrospinning and treated with DBD plasma at varying distances. Optical emission spectroscopy (OES) confirmed the presence of reactive species such as OH radicals, nitrogen (N₂), and nitrogen ions (N₂⁺). These species caused changes in surface morphology, including an increase in fiber diameter. These surface morphological modifications were associated with mechanical properties and hydrophilicity. Furthermore, scaffolds treated at a distance of 1.5 mm showed a degradation rate of up to 70 % after three weeks. The results highlight the potential of DBD plasma treatment to optimize the performance of bone tissue engineering scaffolds.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"12 ","pages":"Article 100501"},"PeriodicalIF":4.1,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144307332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structural isomeric aromatic diamine linkers influenced electrocatalysis of AuNPs: Efficient assessment of hydrazine in environmental water samples","authors":"Karmegam Muthukrishnan ,&nbsp;N.S.K. Gowthaman ,&nbsp;Bharathi Sinduja ,&nbsp;Mathur Gopalakrishnan Sethuraman","doi":"10.1016/j.talo.2025.100503","DOIUrl":"10.1016/j.talo.2025.100503","url":null,"abstract":"<div><div>This electrochemical research explores the conductive behaviour and sensor functionality of citrate-stabilized gold nanoparticles (AuNPs) constructed on a glassy carbon (GC) electrode. Aromatic diamines (ArDAs) with different structural isomeric forms were used as efficient linkers for the attachment of AuNPs, with particular attention given to the detection of hydrazine (HYZ). Careful analysis of three distinct ArDAs, ortho-phenylenediamine (OPD), meta-phenylenediamine (MPD), and para-phenylenediamine (PPD), revealed the formation of self-assembled monolayers (SAMs) of ArDAs on the GC electrode surface. The growth kinetics of ArDA SAMs on GC surfaces were examined using ATR-FT-IR, focusing on the -NH₂ bending vibration region (1592–1631 cm^-1), and the Langmuir adsorption kinetics described the SAM formation, specifically, faster and easier formation of PPD-SAM than OPD and MPD. The PPD SAM on the electrode surface was found to be more compact than OPD and MPD, according to the multi-method analysis. The synthesized AuNPs were anchored on the electrode surface through the free amine groups present in the SAMs and confirmed through scanning electron microscopy, X-ray photoelectron spectroscopy, and cyclic voltammetry. The AuNPs/PPD/GC electrode exhibited superior sensitivity (562 µA mM^-1 cm^-2) and a low detection limit (30 nM) towards HYZ determination. Further, the practicability of the proposed sensor is evaluated by detecting HYZ in environmental water samples and validating the results with the ultra-high-performance liquid chromatography method.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"12 ","pages":"Article 100503"},"PeriodicalIF":4.1,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144338778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Plasmonic and quantitative lateral flow assay for grayscale imaging of neutralizing antibodies SARS-CoV-2","authors":"Karla R. Castro ,&nbsp;Isabela A. Mattioli ,&nbsp;Graziela C. Sedenho ,&nbsp;Thiago Bertaglia ,&nbsp;Antônio F.A. Araújo ,&nbsp;Manoel J.A. Lima ,&nbsp;Beatriz G.R. da Silva ,&nbsp;Mona N. Oliveira ,&nbsp;Iris Todeschini ,&nbsp;Phelipe M. Vitale ,&nbsp;Erika R. Manuli ,&nbsp;Geovana M. Pereira ,&nbsp;Suzete C. Ferreira ,&nbsp;Ester C. Sabino ,&nbsp;Emanuel Carrilho ,&nbsp;Frank N. Crespilho","doi":"10.1016/j.talo.2025.100504","DOIUrl":"10.1016/j.talo.2025.100504","url":null,"abstract":"<div><div>Lateral flow immunoassays (LFIAs) have modernized decentralized mass testing and significantly impacted the healthcare system. It provides a rapid and accessible method for serological testing, which is an important tool for screening patients with past viral phases by detecting antibodies. Here, the development of a quantitative LFIA is presented, in which the receptor-binding domain of Spike protein-specific antibody (anti-S-RBD) in serum samples from previously infected with SARS-CoV-2 patients form an immune complex with the RBD protein immobilized on gold nanoparticles. For quantitative measurements, a methodology was developed based on the plasmonic behavior of gold nanoparticles and using a digital camera that processes images of the test lines in a closed chamber using the CYMK color system. The limits of detection and quantification were 0.22 and 0.70 µg mL^–1, respectively. The proposed device has a manufacturing cost of less than US$ 1 from synthesizing the bioconjugates, assembly of the LFIA strips, and 3D printing of the cassettes. The platform could detect anti-S-RBD antibodies in human serum samples and can be particularly useful in strategies for monitoring IgG levels in the population.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"12 ","pages":"Article 100504"},"PeriodicalIF":4.1,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144322060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Label-free masterful spectrofluorimetric systems for minuscule tracking of natural antioxidant vincamine in the pharmaceutical, environmental, and biological samples: Comparative greenness, whiteness, and blueness appraisal","authors":"Eman Yosrey ,&nbsp;Heba Elmansi ,&nbsp;Shereen Shalan ,&nbsp;Jenny Jeehan Nasr","doi":"10.1016/j.talo.2025.100502","DOIUrl":"10.1016/j.talo.2025.100502","url":null,"abstract":"<div><div>In this work, we present two label-free spectrofluorimetric systems for the swift quantification of vincamine (VN) in various matrices without the need for knotty fluorescent dyes, drastic conditions, or expensive instrumentation, which are key merits of the quantifying procedures. The first method (Method I) relied on the direct mix-and-read assay for exploiting the intrinsic fluorescence of VN, adopting λ_ex/em of 272/334 nm using water as a diluting solvent. The method fitted linearity across the concentrations of 1.00 – 10.00 µg mL⁻¹. In the second method (Method II), upon turning off the photoinduced electron transfer (PET) of tertiary amine in the piperidine moiety to the indole scaffold using 0.1 M hydrochloric acid, the fluorescent signal was augmented up to 158 %. This commendable boost in the fluorescent sensitivity allowed the minute detection of VN in spiked human plasma with a standard deviation not exceeding 1.30. Using the acid-blocked PET-based probe, the fluorescent signal was linearly correlated with VN concentration across 0.25 – 6.00 µg mL⁻¹ using λ_ex/em of 277/323 nm. These streamlined procedures proficiently evaluated VN in both the sole and co-formulated capsules without any significant interference from capsule filler material or the co-formulated medication “piracetam”. In addition, the two submitted procedures were successfully executed to check VN through weight variation testing in the Brain-ox® capsules with good acceptance values. The constructed platforms ensemble estimated VN in the environmental samples (tap and river water) with acceptable percentage recoveries and standard deviations (0.95 – 1.65). The procedures' green, white, and blue fitness were appraised through a plethora of computational tools, including GAPI, AGREE, AGREEprep, the RGB 12 algorithm, and BAGI. The evaluation showed that the proposed works effectively strike a compromise between sustainability and functionality postulates. This highlighted that designed approaches are perfectly suited as ecological frameworks for minuscule assaying of VN in crucial pharmaceutical, biological, and environmental samples.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"12 ","pages":"Article 100502"},"PeriodicalIF":4.1,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144338779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Highly selective room temperature detection of NO2 enabled by vanadyl oxygen vacancies in novel bilayer V2O5","authors":"Reshma P R,&nbsp;Arun K Prasad","doi":"10.1016/j.talo.2025.100497","DOIUrl":"10.1016/j.talo.2025.100497","url":null,"abstract":"<div><div>The primary challenge in developing a gas sensor is achieving high selectivity for the target gas. Most sensor materials respond to multiple gases, making it difficult to discern between various toxic gases. The present study reports the enhancement of the selectivity towards NO₂ gas by introducing vanadyl oxygen (O_I) vacancies in novel 2D V₂O₅. The chemical exfoliation process, which is utilized in the present study to synthesize bilayer nanosheets of V₂O₅, intrinsically generates O_I vacancies. The presence of O-vacancy defects, predominantly O_I vacancies, in the sample is confirmed using X-ray photoelectron spectroscopy, photoluminescence spectroscopy, and Raman spectroscopy. The bilayer 2D V₂O₅ showed a highly selective chemiresistive response towards NO₂ gas at room temperature unlike normally observed higher temperature sensor response by V₂O₅, typically above 100 °C. Along with the effect of high surface to volume ratio, the room temperature gas sensing performance by 2D V₂O₅ stems from the presence of O_I vacancy defects and the consequent increase in the surface activity. In addition, the presence of O_I vacancies leads to highly selective response to NO₂, since NO₂ is a highly oxidizing gas with a pair of lone electrons. Hence, the present study is the first to reveal novel bilayer V₂O₅ sensor with a highly selective response to NO₂ at ambient temperature.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"12 ","pages":"Article 100497"},"PeriodicalIF":4.1,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144298367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}