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Not a laughing matter: revisiting nitric oxide as a potential target for glaucoma therapy. 并非笑谈：重新审视一氧化氮作为青光眼治疗的潜在靶点。
IF 3 3区 材料科学
ACS Applied Electronic Materials Pub Date : 2025-03-01 Epub Date: 2024-06-26 DOI: 10.4103/mgr.MEDGASRES-D-24-00004
Ayobami Adebayo, Eyitayo Adebayo
{"title":"Not a laughing matter: revisiting nitric oxide as a potential target for glaucoma therapy.","authors":"Ayobami Adebayo, Eyitayo Adebayo","doi":"10.4103/mgr.MEDGASRES-D-24-00004","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00004","url":null,"abstract":"","PeriodicalId":3,"journal":{"name":"ACS Applied Electronic Materials","volume":"15 1","pages":"112-113"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515057/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unveiling the link: exploring muscle oxygen saturation in fibromyalgia and its implications for symptomatology and therapeutic strategies. 揭示联系：探索纤维肌痛中的肌肉氧饱和度及其对症状学和治疗策略的影响。
IF 3 3区 材料科学
ACS Applied Electronic Materials Pub Date : 2025-03-01 Epub Date: 2024-04-21 DOI: 10.4103/mgr.MEDGASRES-D-24-00013
Alejandro Rubio-Zarapuz, Jose A Parraca, José Francisco Tornero-Aguilera, Vicente J Clemente-Suárez
{"title":"Unveiling the link: exploring muscle oxygen saturation in fibromyalgia and its implications for symptomatology and therapeutic strategies.","authors":"Alejandro Rubio-Zarapuz, Jose A Parraca, José Francisco Tornero-Aguilera, Vicente J Clemente-Suárez","doi":"10.4103/mgr.MEDGASRES-D-24-00013","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00013","url":null,"abstract":"<p><p>Fibromyalgia, characterized as a complex chronic pain syndrome, presents with symptoms of pervasive musculoskeletal pain, significant fatigue, and pronounced sensitivity at specific anatomical sites. Despite extensive research efforts, the origins of fibromyalgia remain enigmatic. This narrative review explores the intricate relationship between muscle oxygen saturation and fibromyalgia, positing that disruptions in the oxygenation processes within muscle tissues markedly influence the symptom profile of this disorder. Muscle oxygen saturation, crucial for muscle function, has been meticulously investigated in fibromyalgia patients through non-invasive techniques such as near-infrared spectroscopy and magnetic resonance imaging. The body of evidence consistently indicates substantial alterations in oxygen utilization within muscle fibers, manifesting as reduced efficiency in oxygen uptake during both rest and physical activity. These anomalies play a significant role in fibromyalgia's symptomatology, especially in terms of chronic pain and severe fatigue, potentially creating conditions that heighten pain sensitivity and accumulate metabolic byproducts. Hypothesized mechanisms for these findings encompass dysfunctions in microcirculation, mitochondrial irregularities, and autonomic nervous system disturbances, all meriting further research. Understanding the dynamics of muscle oxygen saturation in fibromyalgia is of paramount clinical importance, offering the potential for tailored therapeutic approaches to alleviate symptoms and improve the quality of life for sufferers. This investigation not only opens new avenues for innovative research but also fosters hope for more effective treatment strategies and improved outcomes for individuals with fibromyalgia.</p>","PeriodicalId":3,"journal":{"name":"ACS Applied Electronic Materials","volume":"15 1","pages":"58-72"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515064/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gas-related pathological events and therapeutic failures: a case of oxygen at the microcirculatory and lymphatic level. 与气体有关的病理事件和治疗失败：微循环和淋巴层面的氧气案例。
IF 3 3区 材料科学
ACS Applied Electronic Materials Pub Date : 2025-03-01 Epub Date: 2024-09-25 DOI: 10.4103/mgr.MEDGASRES-D-24-00047
Gerardo Tricarico, Mauro Poggialini, Valter Travagli
{"title":"Gas-related pathological events and therapeutic failures: a case of oxygen at the microcirculatory and lymphatic level.","authors":"Gerardo Tricarico, Mauro Poggialini, Valter Travagli","doi":"10.4103/mgr.MEDGASRES-D-24-00047","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00047","url":null,"abstract":"","PeriodicalId":3,"journal":{"name":"ACS Applied Electronic Materials","volume":"15 1","pages":"124-125"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515068/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hydrogen sulfide: an emerging gasotransmitter involved in the survival of pancreatic islets during diabetes therapy. 硫化氢：糖尿病治疗过程中与胰岛存活有关的一种新兴气体递质。
IF 3 3区 材料科学
ACS Applied Electronic Materials Pub Date : 2025-03-01 Epub Date: 2024-10-02 DOI: 10.4103/mgr.MEDGASRES-D-24-00067
Udayakumar Karunakaran
{"title":"Hydrogen sulfide: an emerging gasotransmitter involved in the survival of pancreatic islets during diabetes therapy.","authors":"Udayakumar Karunakaran","doi":"10.4103/mgr.MEDGASRES-D-24-00067","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00067","url":null,"abstract":"","PeriodicalId":3,"journal":{"name":"ACS Applied Electronic Materials","volume":"15 1","pages":"136-138"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New approach of modern pharmacology: from gasotransmitters to traditional mineral drugs. 现代药理学的新方法：从气体递质到传统矿物药。
IF 3 3区 材料科学
ACS Applied Electronic Materials Pub Date : 2025-03-01 Epub Date: 2024-06-26 DOI: 10.4103/mgr.MEDGASRES-D-24-00022
Yefan Duan, Jianfei Sun
{"title":"New approach of modern pharmacology: from gasotransmitters to traditional mineral drugs.","authors":"Yefan Duan, Jianfei Sun","doi":"10.4103/mgr.MEDGASRES-D-24-00022","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00022","url":null,"abstract":"","PeriodicalId":3,"journal":{"name":"ACS Applied Electronic Materials","volume":"15 1","pages":"139-141"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515075/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Warm alkaline hydrogen peroxide solution as an oxygen-releasing antihypoxic drug: potential benefits and applications. 温碱性过氧化氢溶液作为一种释放氧气的抗缺氧药物：潜在的益处和应用。
IF 3 3区 材料科学
ACS Applied Electronic Materials Pub Date : 2025-03-01 Epub Date: 2024-10-02 DOI: 10.4103/mgr.MEDGASRES-D-24-00058
Anatoly N Osipov, Natalya A Urakova, Aleksandr L Urakov, Petr D Shabanov
{"title":"Warm alkaline hydrogen peroxide solution as an oxygen-releasing antihypoxic drug: potential benefits and applications.","authors":"Anatoly N Osipov, Natalya A Urakova, Aleksandr L Urakov, Petr D Shabanov","doi":"10.4103/mgr.MEDGASRES-D-24-00058","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00058","url":null,"abstract":"","PeriodicalId":3,"journal":{"name":"ACS Applied Electronic Materials","volume":"15 1","pages":"134-135"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515061/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hydrogen sulfide: a rising star for cancer treatment. 硫化氢：治疗癌症的新星。
IF 3 3区 材料科学
ACS Applied Electronic Materials Pub Date : 2025-03-01 Epub Date: 2024-08-02 DOI: 10.4103/mgr.MEDGASRES-D-24-00016
Zixin Wang, Yin Wang
{"title":"Hydrogen sulfide: a rising star for cancer treatment.","authors":"Zixin Wang, Yin Wang","doi":"10.4103/mgr.MEDGASRES-D-24-00016","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00016","url":null,"abstract":"","PeriodicalId":3,"journal":{"name":"ACS Applied Electronic Materials","volume":"15 1","pages":"114-116"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515077/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular hydrogen gas and its therapeutic potential in recent disease progression. 分子氢气及其在近期疾病进展中的治疗潜力。
IF 3 3区 材料科学
ACS Applied Electronic Materials Pub Date : 2025-03-01 Epub Date: 2024-09-25 DOI: 10.4103/mgr.MEDGASRES-D-24-00012
Md Habibur Rahman, Cheol-Su Kim, Kyu-Jae Lee
{"title":"Molecular hydrogen gas and its therapeutic potential in recent disease progression.","authors":"Md Habibur Rahman, Cheol-Su Kim, Kyu-Jae Lee","doi":"10.4103/mgr.MEDGASRES-D-24-00012","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00012","url":null,"abstract":"","PeriodicalId":3,"journal":{"name":"ACS Applied Electronic Materials","volume":"15 1","pages":"120-121"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515071/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative study on the anti-inflammatory and protective effects of different oxygen therapy regimens on lipopolysaccharide-induced acute lung injury in mice. 不同氧疗方案对脂多糖诱发的小鼠急性肺损伤的抗炎和保护作用的比较研究。
IF 3 3区 材料科学
ACS Applied Electronic Materials Pub Date : 2025-03-01 Epub Date: 2024-09-25 DOI: 10.4103/mgr.MEDGASRES-D-24-00044
Xinhe Wu, Yanan Shao, Yongmei Chen, Wei Zhang, Shirong Dai, Yajun Wu, Xiaoge Jiang, Xinjian Song, Hao Shen
{"title":"Comparative study on the anti-inflammatory and protective effects of different oxygen therapy regimens on lipopolysaccharide-induced acute lung injury in mice.","authors":"Xinhe Wu, Yanan Shao, Yongmei Chen, Wei Zhang, Shirong Dai, Yajun Wu, Xiaoge Jiang, Xinjian Song, Hao Shen","doi":"10.4103/mgr.MEDGASRES-D-24-00044","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00044","url":null,"abstract":"<p><p>Oxygen therapy after acute lung injury can regulate the inflammatory response and reduce lung tissue injury. However, the optimal exposure pressure, duration, and frequency of oxygen therapy for acute lung injury remain unclear. In the present study, after intraperitoneal injection of lipopolysaccharide in ICR mice, 1.0 atmosphere absolute (ATA) pure oxygen and 2.0 ATA hyperbaric oxygen treatment for 1 hour decreased the levels of proinflammatory factors (interleukin-1beta and interleukin-6) in peripheral blood and lung tissues. However, only 2.0 ATA hyperbaric oxygen increased the mRNA levels of anti-inflammatory factors (interleukin-10 and arginase-1) in lung tissue; 3.0 ATA hyperbaric oxygen treatment had no significant effect. We also observed that at 2.0 ATA, the anti-inflammatory effect of a single exposure to hyperbaric oxygen for 3 hours was greater than that of a single exposure to hyperbaric oxygen for 1 hour. The protective effect of two exposures for 1.5 hours was similar to that of a single exposure for 3 hours. These results suggest that hyperbaric oxygen alleviates lipopolysaccharide-induced acute lung injury by regulating the expression of inflammatory factors in an acute lung injury model and that appropriately increasing the duration and frequency of hyperbaric oxygen exposure has a better tissue-protective effect on lipopolysaccharide-induced acute lung injury. These results could guide the development of more effective oxygen therapy regimens for acute lung injury patients.</p>","PeriodicalId":3,"journal":{"name":"ACS Applied Electronic Materials","volume":" ","pages":"171-179"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515059/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142349967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A narrative review of gas separation and conservation technologies during xenon anesthesia. 氙气麻醉过程中气体分离和保存技术综述。
IF 3 3区 材料科学
ACS Applied Electronic Materials Pub Date : 2025-03-01 Epub Date: 2024-06-26 DOI: 10.4103/mgr.MEDGASRES-D-24-00002
Steven McGuigan, Brendan F Abrahams, David A Scott
{"title":"A narrative review of gas separation and conservation technologies during xenon anesthesia.","authors":"Steven McGuigan, Brendan F Abrahams, David A Scott","doi":"10.4103/mgr.MEDGASRES-D-24-00002","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00002","url":null,"abstract":"<p><p>Xenon gas has significant advantages over conventional general anesthetic agents but its use has been limited by the cost associated with its production. Xenon also has significant potential for medical use in the treatment of acquired brain injuries and for mental health disorders. As the demand for xenon gas from other industries increases, the costs associated with its medical use are only likely to increase. One solution to mitigate the significant cost of xenon use in research or medical care is the conservation of xenon gas. During delivery of xenon anesthesia, this can be achieved either by separating xenon from the other gases within the anesthetic circuit, conserving xenon and allowing other gases to be excluded from the circuit, or by selectively recapturing xenon utilized during the anesthetic episode at the conclusion of the case. Several technologies, including the pressurization and cooling of gas mixtures, the utilization of gas selective membranes and the utilization of gas selective adsorbents have been described in the literature for this purpose. These techniques are described in this narrative review along with important clinical context that informs how these technologies might be best applied. Whilst these technologies are discussed in the context of xenon general anesthesia, they could be applied in the delivery of xenon gas inhalation for other therapeutic purposes.</p>","PeriodicalId":3,"journal":{"name":"ACS Applied Electronic Materials","volume":"15 1","pages":"93-100"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515081/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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