ACS Applied Nano Materials最新文献

{"title":"Near-Infrared-Responsive Semiconductor Quantum Dots for Solar Photocatalysis","authors":"Jen-An Shih,&nbsp;Shan-Jen Yang,&nbsp;Chun-Yi Chen*,&nbsp;Masato Sone,&nbsp;Tso-Fu Mark Chang,&nbsp;Ying-Chih Pu* and Yung-Jung Hsu*,&nbsp;","doi":"10.1021/acsanm.5c0062910.1021/acsanm.5c00629","DOIUrl":"https://doi.org/10.1021/acsanm.5c00629https://doi.org/10.1021/acsanm.5c00629","url":null,"abstract":"<p >The development of semiconductor quantum dots (QDs) as near-infrared (NIR)-responsive photocatalysts represents a promising strategy for advancing solar energy conversion and environmental remediation. Unlike conventional photocatalysts, NIR-responsive QDs possess notable optical properties, including tunable bandgap excitations, localized surface plasmon resonance (LSPR), and upconversion capabilities, which enable efficient photon absorption beyond the visible spectrum. This review explores the transformative potential of NIR-responsive QDs in photocatalytic applications, emphasizing mechanistic strategies to exploit the largely untapped NIR segment of the solar spectrum for advanced photocatalytic processes. Recent advances in small-bandgap semiconductors and self-doped plasmonic semiconductors QDs are discussed, highlighting their role in enhancing photocatalytic efficiency through synergistic electronic, plasmonic and photothermal effects. Furthermore, the application of up-conversion processes in extending the photoactive range of QDs is examined, demonstrating their potential for sustainable photocatalysis under NIR irradiation. Finally, we address current challenges in achieving performance optimization, establishing veritable working mechanism, and demonstrating pilot-scale applications, while providing insights into future directions for harnessing NIR-responsive QDs as next-generation photocatalysts. By leveraging these advanced nanomaterials, this review aims to inspire innovative strategies for harnessing the full solar spectrum, ultimately contributing to the realization of a carbon-neutral energy future.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 16","pages":"8154–8166 8154–8166"},"PeriodicalIF":5.3,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143867566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hierarchically Porous Graphitic Aerogels via Thermal Morphogenesis of Proteins for Environmental Remediation","authors":"M. Shaharyar Wani,&nbsp;Bridget Denzer,&nbsp;Nicholas J. Caggiano,&nbsp;Robert K. Prud’homme and Craig B. Arnold*,&nbsp;","doi":"10.1021/acsanm.5c0115610.1021/acsanm.5c01156","DOIUrl":"https://doi.org/10.1021/acsanm.5c01156https://doi.org/10.1021/acsanm.5c01156","url":null,"abstract":"<p >Hierarchically porous monolithic graphitic sheet-based aerogels (HGA) with high surface area and ultralow density have drawn massive attention for applications in catalysis, energy storage/conversion, water purification, and beyond. However, syntheses of these materials rely on harsh and nonsustainable chemical reagents and/or template-based methods, while the resulting structures generally lack covalent integration, compromising their properties. Herein, we demonstrate a self-foaming mechanism for green and scalable synthesis of HGA using protein precursors. Rather than creating a solid composite and exchanging the sacrificial component with a gas phase, we create a gas phase first and then convert the liquid into a solid phase. The controlled heating of protein induces intrinsic foaming via softening, gas evolution, and carbonization/graphitization, resulting in an HGA composed of a sheet and fiber-like framework. Our investigation of processing-structure–property relationships elucidates the interplay between synthesis variables and aerogel structure/properties, enabling deliberate control over microstructural features. Notably, we demonstrate more than an order-of-magnitude variation in density and over a 7-fold increase in compressive strength by controlling the synthesis protocol. This study opens doors to a green and scalable approach to synthesizing HGAs with customizable microstructures and properties, making them promising for a broad spectrum of applications such as environmental remediation and energy storage.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 16","pages":"8464–8472 8464–8472"},"PeriodicalIF":5.3,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143867630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aptamer-Gold Nanocluster Coupling–Decoupling for Efficient Cancer Theranostics","authors":"Huanhuan Sun,&nbsp;Yuchen Wu,&nbsp;Lamei Liu,&nbsp;Yan Zhou,&nbsp;Lin He,&nbsp;Lanlin Qi,&nbsp;Min Hou,&nbsp;Jianbo Liu*,&nbsp;Mingmin Huang* and Xiaoxiao He*,&nbsp;","doi":"10.1021/acsanm.5c0060910.1021/acsanm.5c00609","DOIUrl":"https://doi.org/10.1021/acsanm.5c00609https://doi.org/10.1021/acsanm.5c00609","url":null,"abstract":"<p >Despite noteworthy progress in biomedical applications, aptamers encounter substantial obstacles in the realm of in vivo cancer theranostics, primarily due to the susceptibility of native aptamers to degradation and the compromised affinity of engineered aptamers. Herein, an aptamer/gold nanoclusters (Apt-M/AuNCs)-based system, featuring a facile noncovalent coupling and biomarker-responsive decoupling mechanism, is developed for activated tumor imaging and integrated gene-chemotherapy. Specifically, we employed the tumor biomarker legumain as a model imaging switch and manganese superoxide dismutase (MnSOD) mRNA as a therapeutic target, respectively, facilitated by tailored peptides (bioligands of AuNCs) and the aptamer AS1411-antisense mRNA (Apt-M). Compared to monomeric Apt-M, the Apt-M/AuNCs system exhibited significant improvements in both stability and binding affinity, subsequently translating to notable enhancements in imaging contrast and therapeutic efficacy. Endowed with remarkable biostability, affinity, and specificity, our work offers a facile route for efficient aptamer functionalization and subsequently superior theranostics performance, thereby holding great potential for broadening the application of aptamers into an ever-growing array of research fields.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 16","pages":"8144–8153 8144–8153"},"PeriodicalIF":5.3,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143867287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DNA Origami-Based Lattice Actuator for Constructing Multi-Responsive, Multi-Reconfigurable Artificial Nanostructures","authors":"Yuri Kobayashi,&nbsp;Reo Toho and Yuki Suzuki*,&nbsp;","doi":"10.1021/acsanm.5c0053210.1021/acsanm.5c00532","DOIUrl":"https://doi.org/10.1021/acsanm.5c00532https://doi.org/10.1021/acsanm.5c00532","url":null,"abstract":"<p >Advancements in structural nucleic acid nanotechnology have enabled the construction of diverse stimuli-responsive nanomachines using molecular self-assembly. These efforts have expanded to include the development of multi-reconfigurable nanodevices that exhibit complex motions, requiring the combinatorial and reversible operation of multiple movable components. Here, we report a multi-reconfigurable DNA origami lattice actuator capable of transforming into distinct shapes based on combinations of external cues. The structure comprises nine frames, each constructed from a rigid 4-helix bundle connected by flexible single-stranded DNAs. Except for the central frame, each frame contains two bridge strands that form tetraplex structures, such as i-motifs or G-quadruplexes, in response to changes in pH or the presence of K⁺. By modulating tetraplex formation through chemical cues and complementary suppressor strands, the shapes of individual frames are sequentially reconfigured, enabling the lattice actuator to adopt different configurations. This simple yet modular design approach facilitates the development of intelligent biomaterials capable of specific transformations in response to combinations of external stimuli.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 16","pages":"8106–8112 8106–8112"},"PeriodicalIF":5.3,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsanm.5c00532","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143867352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integration of Carbon-Doped ZnO/S Cathode and Silicon/Graphene Nanoplate Anode for Silicon–Sulfur Batteries","authors":"Navid Aslfattahi*,&nbsp;Maryam Sadat Kiai,&nbsp;Nilgun Baydogan,&nbsp;Lingenthiran Samylingam,&nbsp;Kumaran Kadirgama* and Chee Kuang Kok,&nbsp;","doi":"10.1021/acsanm.5c0056310.1021/acsanm.5c00563","DOIUrl":"https://doi.org/10.1021/acsanm.5c00563https://doi.org/10.1021/acsanm.5c00563","url":null,"abstract":"<p >The advancement of modified anodes and cathodes for the next generation of sulfur-based batteries has become a prominent focus of research. This study introduces a methodology for the design and synthesis of silicon/graphene nanoplates (Si/GNPs) through a one-step hydrothermal process. Additionally, we suggest nanocomposite carbon-doped ZnO/S as a potential cathode material through the urea-assisted thermal decomposition of zinc acetate. C/ZnO/S has the special capability to alleviate volume change and hinder sulfur dissolution of the electrolyte. Additionally, ZnO possesses a superior distribution of sulfur in the ZnO/S composite and enhanced sulfur conversion reactions. This configuration of the cell is mentioned for the first time and shows an outstanding retention capacity of 916 mAh g^–1 after 500 cycles, indicating a minimal decay rate of merely 0.047% per cycle.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 16","pages":"8113–8121 8113–8121"},"PeriodicalIF":5.3,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143867565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aqueous Hydrogenation of Rosin Catalyzed by Amphiphilic Ni–Cu Nanocatalysts","authors":"Fengli Yu,&nbsp;Minghao Bao,&nbsp;Jiahao Li,&nbsp;Bing Yuan,&nbsp;Congxia Xie* and Shitao Yu*,&nbsp;","doi":"10.1021/acsanm.5c0071410.1021/acsanm.5c00714","DOIUrl":"https://doi.org/10.1021/acsanm.5c00714https://doi.org/10.1021/acsanm.5c00714","url":null,"abstract":"<p >An amphiphilic mesoporous silica-coated N-doped hollow mesoporous carbon spherical nanomaterial (N-HMC@MS) with a large pore diameter and high nitrogen content has been successfully prepared using a typical emulsion-induced interface assembly strategy and a high-temperature limited carbonization method. To solve the problem of easy aggregation of Ni nanoparticles and improve their catalytic activity, bimetallic amphiphilic Ni-based catalysts (Ni–Cu/N-HMC@MS) were prepared by loading Ni and Cu nanoparticles on N-HMC@MS by the impregnation-hydrogen reduction method. The catalysts were fully characterized and applied to the hydrogenation of rosin macromolecules. The larger pore size of the catalysts makes mass transfer more convenient, and the doped nitrogen elements in the material can provide more coordination anchoring sites for metal nanoparticles. Amphiphilicity can not only improve the dispersion of catalysts in water but also increase the affinity for organic reaction substrates, which can realize effective green catalysis in aqueous medium. Nonprecious metal Ni as the active component greatly reduces the production cost. The influence of various reaction conditions on the catalytic reaction was investigated, and the best reaction process was selected. The catalyst Ni₅–Cu₁/N-HMC@MS shows good activity and high stability, which can be compared with precious metal catalysts Pd and Ru. This study points out an environmentally friendly direction for the further processing and exploitation of rosin resources and brings an idea for the development of aqueous catalytic hydrogenation with nonprecious metal catalysts.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 16","pages":"8199–8208 8199–8208"},"PeriodicalIF":5.3,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143867631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Printable Two-Dimensional Nanomaterials: Approaching Low-Cost Electrodes for High-Efficiency Li/Na-Ion Batteries and Photodetectors","authors":"Ruei-Hong Cyu,&nbsp;Chuan-Hsun Wang,&nbsp;Arumugam Manikandan,&nbsp;Shu-Chi Wu,&nbsp;Shin-Yi Tang,&nbsp;Po-Wen Chiu*,&nbsp;Ray-Hua Horng* and Yu-Lun Chueh*,&nbsp;","doi":"10.1021/acsanm.5c0059010.1021/acsanm.5c00590","DOIUrl":"https://doi.org/10.1021/acsanm.5c00590https://doi.org/10.1021/acsanm.5c00590","url":null,"abstract":"<p >Molybdenum disulfide (MoS₂)/graphene composites have garnered significant attention as promising materials for high-performance electrodes and optoelectronic devices owing to their exceptional electrochemical and photodetection properties. However, the fabrication of these composite electrodes remains challenging, primarily due to the low yield, suboptimal quality, and structural stability of MoS₂ and graphene, which pose significant barriers to their practical applications. Here, a high-performance inkjet-printed flexible electrode based on a MoS₂-graphene heterostructure is demonstrated. The process parameters during ejection and the adhesion force between inkjet-printed film and the substrate have been systematically studied. As a result, it allows the rapid and cost-effective production of robust anodes for lithium-ion batteries (LIBs), sodium-ion batteries (SIBs), and high-performance photodetectors. The graphene-MoS₂ NF anodes demonstrate remarkable specific capacities of 856 mAh g^–1 after 450 cycles for LIBs and 505 mAh g^–1 after 650 cycles for SIBs at 0.6 A g^–1, exhibiting superior cycling stability and rate capability compared to doctor-blade-coated anodes. The enhanced stability is attributed to the inkjet printing’s precise layer-by-layer deposition, leading to better interfacial adhesion and reduced structural degradation during cycling. Moreover, the photodetectors, featuring MoS₂ nanosheets (NSs) as the channel and graphene as the electrode, achieve enhanced photocurrents and high on/off ratios with the flexible devices maintaining excellent performance after over 500 bending cycles. These findings underscore the potential of inkjet-printed graphene-MoS₂ heterostructures for scalable, durable, and multifunctional applications in energy storage and optoelectronics, showcasing the advantages of high uniformity and rapid low-cost fabrication.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 16","pages":"8133–8143 8133–8143"},"PeriodicalIF":5.3,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsanm.5c00590","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143867580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vacancy-Enhanced Biotite Nanosheets for Optical Limiters","authors":"Dipanwita Mitra,&nbsp;Md. Nur Hasan,&nbsp;Chinmayee Chowde Gowda,&nbsp;Gelu Costin,&nbsp;Chandra Sekhar Tiwary*,&nbsp;Debjani Karmakar* and Prasanta Kumar Datta*,&nbsp;","doi":"10.1021/acsanm.5c0045410.1021/acsanm.5c00454","DOIUrl":"https://doi.org/10.1021/acsanm.5c00454https://doi.org/10.1021/acsanm.5c00454","url":null,"abstract":"<p >The advancement of high-power lasers necessitates the development of effective optical limiting materials to prevent the radiation damage of both sensors and optical vision. Atomically thin two-dimensional (2D) silicates, by virtue of their unique optical properties, have enabled several applications, including optical limiting. This study demonstrates the thickness-dependent nonlinear absorption and optical limiting capabilities of 2D biotite, a silicate mineral, by using femtosecond laser pulses. With decreasing thickness from a few layers to a monolayer, both the third-order nonlinear susceptibility and the two-photon absorption coefficient of this material manifest an increase by 2 orders of magnitude. Monolayer biotite exhibits an optical limiting threshold of 1.51 mJ/cm², surpassing the respective values for other conventional two-dimensional systems like graphene and transition metal dichalcogenides. The enhancement of the two-photon absorption is intimately tied up with the quantum confinement of the 2D system and its underlying intrinsic lattice defects. An elaborate first-principles investigation of the layer-dependent electronic structure of 2D biotite with various possible defect geometries indicates the presence of highly localized midgap levels primarily associated with Si and O-p orbitals, which may result in improved two-photon absorption in this system. DFT analyses indicate that disruption of the potassium layer (K-layer) and generation of the oxygen vacancies as a result of the liquid-phase exfoliation process may account for the generation of midgap states leading to an enhanced two-photon absorption in systems subjected to prolonged exfoliation periods. Our findings can be extremely beneficial for the development of highly efficient optical limiters utilizing 2D silicates at relatively much lower fluences.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 16","pages":"8187–8198 8187–8198"},"PeriodicalIF":5.3,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143867577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic Photothermal and Photodynamic Therapy against Bacterial Infections Using Carbon Quantum Dots Modified Molybdenum Disulfide","authors":"Yayu Chen,&nbsp;Pengcheng Huang,&nbsp;Wenting Hong,&nbsp;Wanqing Xu,&nbsp;Xiaoping Chen,&nbsp;Shuxian Li,&nbsp;Chaojin Liu,&nbsp;Yuansheng Wang,&nbsp;Xiaoyan Zhang*,&nbsp;Yuqiong Wu* and Fangchuan Chen*,&nbsp;","doi":"10.1021/acsanm.5c0149110.1021/acsanm.5c01491","DOIUrl":"https://doi.org/10.1021/acsanm.5c01491https://doi.org/10.1021/acsanm.5c01491","url":null,"abstract":"<p >Oral and maxillofacial infections are primarily caused by pyogenic bacterial infections, with common pathogens including <i>Staphylococcus aureus</i> and <i>Escherichia coli</i>. In this study, we developed a nonantibiotic antibacterial material, carbon quantum dots (CQDs) modified molybdenum disulfide (MoS₂), through a well-designed fabrication process. CQDs were used as highly efficient cocatalysts to enhance the near-infrared absorption capacity of the composite. Under near-infrared light (NIR) irradiation (1.5 W/cm² for 5 min), the 18.75% CQDs/MoS₂ composite, with CQDs concentration reaching 18.75%, exhibited complete antibacterial activity, demonstrating 100% efficacy against both <i>S. aureus</i> and <i>E. coli</i>. In addition, under NIR irradiation, the obtained CQDs/MoS₂ displayed remarkable wound healing performance, as well as antioxidative and anti-inflammatory capabilities. The improved antibacterial and wound healing performance were attributed to the synergistic effects of hyperthermia-mediated photothermal therapy (PTT) and reactive oxygen species (ROS)-mediated photodynamic therapy (PDT). This study offers a promising approach for managing maxillofacial wound infections.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 16","pages":"8499–8510 8499–8510"},"PeriodicalIF":5.3,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143867438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Construction of pH-Responsive Copper Sulfide Nanocomposites and Their Photothermal/Chemodynamic Synergistic Antibacterial Studies","authors":"Zexing Yang,&nbsp;Yu Liu,&nbsp;Jun Wang,&nbsp;Wanzhen Li,&nbsp;Ping Song,&nbsp;Longbao Zhu,&nbsp;Weiwei Zhang,&nbsp;Lin Gui and Fei Ge*,&nbsp;","doi":"10.1021/acsanm.5c0033510.1021/acsanm.5c00335","DOIUrl":"https://doi.org/10.1021/acsanm.5c00335https://doi.org/10.1021/acsanm.5c00335","url":null,"abstract":"<p >Drug-resistant bacterial biofilm infections represent a significant danger to global public health. The efficacy of conventional antibiotics is not satisfactory enough, photothermal therapy (PTT) in combination with chemodynamic therapy (CDT) is an effective antimicrobial strategy. To reduce bacterial resistance performance and enhance antibacterial ability, this project proposes to construct a nanocomposite CuS-CaO₂–Res@ZIF-8 formed by photothermite CuS nanoparticles as the core and mesoporous organometallic framework ZIF-8 as the shell. This nanocomposite synergized with the group-sensing inhibitor resveratrol for the acid-induced release of antibacterial components. Ultimately, the targeted disruption of biocoated membranes was achieved by the synergistic action of PTT and CDT. The in vitro/in vivo antimicrobial and antibiofilm activity assays of CuS-CaO₂–Res@ZIF-8 were performed to explore its antimicrobial properties. The results indicate that CuS-CaO₂–Res@ZIF-8 can effectively achieve bacterial inhibition while avoiding antibiotics. As a powerful agent against biofilm infections, CuS-CaO₂–Res@ZIF-8 offers a promising strategy for designing antimicrobial nanomaterials tailored to the unique characteristics of the biofilm microenvironment, demonstrating significant potential for future clinical applications.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 16","pages":"8037–8053 8037–8053"},"PeriodicalIF":5.3,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143867441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}