Journal of Functional Foods最新文献

Corrigendum to “Effects of high-protein rice bran fiber on intestinal microbiota composition in healthy older Chinese adults based on in vitro fermentation and a pilot intervention study” [J. Func. Food 139 (2026) 107242] “基于体外发酵和试点干预研究的高蛋白米糠纤维对中国健康老年人肠道菌群组成的影响”[J]。函数。食品139 (2026)107242]

IF 4 2区农林科学

Journal of Functional Foods Pub Date : 2026-05-01 Epub Date: 2026-03-23 DOI: 10.1016/j.jff.2026.107260

Jianqiang Li , Xinyi Lian , Zhaojun Liu , Ge Zhang , Jie Gu , Xin Wang , Jinjun Li , Xiuli Yu , Xiangyu Bian , Jian Kuang , Fangshu Shi , Yuling Li , Zhengxiang Hu , Xiaoqiong Li

引用次数: 0

Molecular docking-guided caffeic acid phenethyl ester/hydroxypropyl-β-cyclodextrin host-guest complexes: Alleviating of colonic inflammation and insights into their synergistic mechanism 分子对接引导的咖啡酸苯乙酯/羟丙基-β-环糊精主客体复合物：减轻结肠炎症及其协同机制的见解

IF 4 2区农林科学

Journal of Functional Foods Pub Date : 2026-03-01 Epub Date: 2026-02-13 DOI: 10.1016/j.jff.2026.107200

Jiayu Li , Qin Huang , Can Li , Dan Wu , Miao Li , Yukun Huang , Xiao Yang , Xianggui Chen , Pengfei Chen , Guangping Luo

{"title":"Molecular docking-guided caffeic acid phenethyl ester/hydroxypropyl-β-cyclodextrin host-guest complexes: Alleviating of colonic inflammation and insights into their synergistic mechanism","authors":"Jiayu Li , Qin Huang , Can Li , Dan Wu , Miao Li , Yukun Huang , Xiao Yang , Xianggui Chen , Pengfei Chen , Guangping Luo","doi":"10.1016/j.jff.2026.107200","DOIUrl":"10.1016/j.jff.2026.107200","url":null,"abstract":"<div><div>Caffeic acid phenethyl ester (CAPE), a prominent polyphenolic compound in propolis, faces limited nutritional application due to its hydrophobicity and low bioavailability. By molecular docking, CAPE/hydroxypropyl-β-cyclodextrin (HP-β-CD) host-guest complexes exhibiting the lowest binding energy were identified and synthesized using saturated aqueous solution-freeze-drying methods, achieving an inclusion efficiency of 96.13% and enhanced storage stability. In vivo studies demonstrated that CAPE/HP-β-CD complexes effectively alleviated colonic inflammation by suppressing NF-κB pathway, restoring mucosal integrity and levels of short-chain fatty acids (SCFAs). Imaging flow cytometry revealed that HP-β-CD enhances cellular uptake of CAPE through an endocytosis-mediated mechanism, surpassing passive diffusion, thereby increasing intracellular CAPE accumulation in Caco-2 cells from 4.63 mg/g to 44.54 mg/g. Bioinformatic analyses further indicated that these complexes exhibited superior efficacy compared to CAPE in ameliorating gut microbial dysbiosis and promoting the proliferation of several bacterial genera within the <em>Lachnospiraceae</em> family, which contribute to maintaining intestinal homeostasis and producing SCFAs. Additionally, the majority of microbiota exhibited negative correlations with key inflammatory markers, including the beneficial genus <em>Bifidobacterium</em>, which is associated with butyric acid production. This study highlights the utility of molecular docking in the rational high-throughput screening of cyclodextrin-based carriers and elucidates the multifaceted mechanisms by which CAPE/HP-β-CD complexation enhances the efficacy of nutritional interventions against colonic inflammation.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"138 ","pages":"Article 107200"},"PeriodicalIF":4.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146171575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Citrus polyphenols for bone health: A systematic review of experimental and human studies 柑橘多酚对骨骼健康：实验和人体研究的系统综述

IF 4 2区农林科学

Journal of Functional Foods Pub Date : 2026-03-01 Epub Date: 2026-02-05 DOI: 10.1016/j.jff.2026.107177

Simone Perna , Nora Cornelli , Asmita Acharya , Eleonora Patta , Giuseppe Mazzola , Mariangela Rondanelli , Patrizia Riso

{"title":"Citrus polyphenols for bone health: A systematic review of experimental and human studies","authors":"Simone Perna , Nora Cornelli , Asmita Acharya , Eleonora Patta , Giuseppe Mazzola , Mariangela Rondanelli , Patrizia Riso","doi":"10.1016/j.jff.2026.107177","DOIUrl":"10.1016/j.jff.2026.107177","url":null,"abstract":"<div><div>Citrus fruits are rich in flavanones hesperidin, naringenin, neohesperidin, and neoeriocitrin with emerging osteoprotective potential. This PRISMA-compliant systematic review integrated evidence from in vitro, in vivo, and human studies identified across PubMed, Scopus, and Google Scholar (2014–2025). Fifteen studies met eligibility (8 in vitro, 6 in vivo, 1 randomized human trial). Preclinical findings indicate enhanced osteoblastogenesis via ERK/Smad and Wnt/β-catenin signalling and suppression of osteoclastogenesis through RANKL–NF-κB/NFATc1, alongside reduced oxidative and inflammatory stress. Animal models demonstrated improved trabecular microarchitecture and accelerated fracture healing. In the only human trial found, hesperidin plus calcium improved calcium retention by ∼5.5% versus calcium alone. Overall citrus flavanones seem to exhibit convergent anabolic and anti-resorptive effects; however, long-duration, well-powered clinical trials with standardized formulations are required to establish efficacy for osteoporosis prevention.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"138 ","pages":"Article 107177"},"PeriodicalIF":4.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146171577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A novel antitumor peptide from silkworm pupae (Bombyx mori): Purification, characterization, and mechanism 一种从家蚕蛹中提取的新型抗肿瘤肽：纯化、表征及作用机制

IF 4 2区农林科学

Journal of Functional Foods Pub Date : 2026-03-01 Epub Date: 2026-02-03 DOI: 10.1016/j.jff.2026.107176

Guanyu Jiang, Yingfei Su, Liqing Tang, Yue Zhang, Xueping Jiang, Jianglong He, Ping Wu, Sitong Chen, Hao Li, Ran Zhang, Zhongzheng Gui

{"title":"A novel antitumor peptide from silkworm pupae (Bombyx mori): Purification, characterization, and mechanism","authors":"Guanyu Jiang, Yingfei Su, Liqing Tang, Yue Zhang, Xueping Jiang, Jianglong He, Ping Wu, Sitong Chen, Hao Li, Ran Zhang, Zhongzheng Gui","doi":"10.1016/j.jff.2026.107176","DOIUrl":"10.1016/j.jff.2026.107176","url":null,"abstract":"<div><div>Bioactive peptide Tyr-Ala-Ser-Pro-Val-His (YASPVH) was purified from silkworm pupa protein enzymatic hydrolysates, and exhibited potent antiproliferative activity against breast cancer HCC-1937 cells. Besides, YASPVH induced G1 phase cell cycle arrest and suppressed HCC-1937 cell migration and invasion. YASPVH also triggered mitochondrial dysfunction, characterized by membrane potential depolarization and reactive oxygen species (ROS) accumulation, ultimately inducing mitochondrial apoptosis via the Bcl-2/Bax/caspase-3 pathway. Additionally, YASPVH promoted excessive intracellular ROS accumulation, leading to endoplasmic reticulum (ER) stress. This was evidenced by significantly elevated cytosolic Ca<sup>2+</sup> levels and upregulation of ER stress markers PERK, ATF4, and CHOP. YASPVH furthermore inhibited the epithelial-mesenchymal transition process (EMT) by promoting E-cadherin expression while suppressing Vimentin and N-cadherin expression. Collectively, these results demonstrate that YASPVH exerts its antitumor effect by inhibiting proliferation and metastasis, and inducing apoptosis in HCC-1937 cells. This study identifies YASPVH as a promising candidate and provides a novel strategy for breast cancer treatment.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"138 ","pages":"Article 107176"},"PeriodicalIF":4.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146171643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Structural characterization and hypolipidemic activity of polysaccharides from finger citron 佛手柑多糖的结构表征及降血脂活性

IF 4 2区农林科学

Journal of Functional Foods Pub Date : 2026-03-01 Epub Date: 2026-02-05 DOI: 10.1016/j.jff.2026.107185

Juan-Juan Ma , Xi Xie , Lu-Kai Ma , Qin Wang , Geng-Sheng Xiao , Hui-Fan Liu

{"title":"Structural characterization and hypolipidemic activity of polysaccharides from finger citron","authors":"Juan-Juan Ma , Xi Xie , Lu-Kai Ma , Qin Wang , Geng-Sheng Xiao , Hui-Fan Liu","doi":"10.1016/j.jff.2026.107185","DOIUrl":"10.1016/j.jff.2026.107185","url":null,"abstract":"<div><div>In this study, the structural characterization and hypolipidemic activity in vivo of finger citron polysaccharide (FCP) were investigated. The FCP consisted of [→t)-Ara(f)-(1→], [→5)-Ara(f)-(1→], and [→4)-Gal(p)-UA-(1→] with the molecular weight of 46.35 KDa. FCP significantly decreased the levels of total cholesterol (TC), triglyceride (TG), low density cholesterol (LDL-C), phenylpropionate aminotransferase (ALT), and aspartate aminotransferase (AST) and increased the level of high density cholesterol (HDL<img>C) in the serum of mice (<em>P</em> < 0.05). Besides, FCP could significantly improve the antioxidant enzymes activities and decreased the liver lipid metabolism indexes (<em>P</em> < 0.05). AMPK/ACC and PPARα/LXRα were used to investigate the hypolipidemic mechanism of FCP, which indicated that FCP could up-regulate the protein and gene levels of AMPK, acetyl-CoA carboxylase(ACC), PPARα and LXRα. This study provides an important basis of FCP for inhibiting the occurrence of metabolic disorders such as hyperlipemia and complications.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"138 ","pages":"Article 107185"},"PeriodicalIF":4.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146171644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Folate-producing Lactiplantibacillus plantarum TXZ 2–26 attenuates H-type hypertension by reshaping gut microbiota and metabolic profiles 产生叶酸的植物乳杆菌txz2 - 26通过重塑肠道微生物群和代谢谱来减轻h型高血压

IF 4 2区农林科学

Journal of Functional Foods Pub Date : 2026-03-01 Epub Date: 2026-02-12 DOI: 10.1016/j.jff.2026.107201

Pu Li , Luyao Liu , Dandan Han , Yuhan Liu , Buke Shi , Huan Liu , Yujie Chen , Yanglei Yi , Yali Cui

{"title":"Folate-producing Lactiplantibacillus plantarum TXZ 2–26 attenuates H-type hypertension by reshaping gut microbiota and metabolic profiles","authors":"Pu Li , Luyao Liu , Dandan Han , Yuhan Liu , Buke Shi , Huan Liu , Yujie Chen , Yanglei Yi , Yali Cui","doi":"10.1016/j.jff.2026.107201","DOIUrl":"10.1016/j.jff.2026.107201","url":null,"abstract":"<div><div>H-type hypertension, characterized by hyperhomocysteinemia and folate deficiency, is influenced by gut microbiota dysbiosis. Supplementation with folate-producing probiotics may offer a therapeutic strategy, but its mechanisms require clarification. Using a hypertensive mouse model induced by L-NAME/high-salt, we evaluated the effects of two <em>Lactiplantibacillus plantarum</em> strains: the high folate-producer TXZ 2–26 and a low-producer control, F4–1. Only TXZ 2–26 significantly attenuated elevations in systolic and diastolic blood pressure, reduced renal inflammation and fibrosis, and improved metabolic parameters. This was accompanied by a reversal of hypertension-associated gut dysbiosis—specifically, a decrease in pro-inflammatory taxa (e.g., <em>Porphyromonadaceae</em>) and an increase in beneficial microbes (e.g., <em>Muribaculaceae</em>).Metabolomic analysis revealed that TXZ 2–26 restored host metabolic pathways related to amino acid and lipid metabolism. Crucially, TXZ 2–26 treatment significantly increased folate levels and decreased homocysteine (HCY) in both feces and serum, establishing a strong inverse correlation between them. HCY levels were, in turn, positively correlated with blood pressure. Our findings demonstrate that the antihypertensive effect of <em>L. plantarum</em> TXZ 2–26 is specifically dependent on its high folate-producing capacity, which modulates the gut microbiota, reprograms host metabolism, and corrects the folate-HCY axis imbalance.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"138 ","pages":"Article 107201"},"PeriodicalIF":4.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146171652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Siraitia grosvenorii extract (Sweet Mogrosides) alleviates LPS-induced depressive-like behaviors through modulating neuroinflammation-pyroptosis axis 罗汉果提取物（甜罗汉果苷）通过调节神经炎症-焦死轴减轻lps诱导的抑郁样行为

IF 4 2区农林科学

Journal of Functional Foods Pub Date : 2026-03-01 Epub Date: 2026-01-29 DOI: 10.1016/j.jff.2026.107170

Yuan-yu Yang , Li-guo Li , Shang Li , Ya Su , Li-ming Liu , Quan Tang , Rui Qiu , Yong-Biao Li , Yong Cheng , Hui Zhou

{"title":"Siraitia grosvenorii extract (Sweet Mogrosides) alleviates LPS-induced depressive-like behaviors through modulating neuroinflammation-pyroptosis axis","authors":"Yuan-yu Yang , Li-guo Li , Shang Li , Ya Su , Li-ming Liu , Quan Tang , Rui Qiu , Yong-Biao Li , Yong Cheng , Hui Zhou","doi":"10.1016/j.jff.2026.107170","DOIUrl":"10.1016/j.jff.2026.107170","url":null,"abstract":"<div><div>This study investigates the antidepressant effects of Sweet Mogrosides (SMG) derived from <em>Siraitia grosvenorii</em> (SG), focusing on the outcomes of its oral administration and its novel dual-axis modulation of the neuroinflammation-pyroptosis pathway in an LPS-induced depression model. Behaviorally, oral SMG treatment significantly alleviated depressive-like behaviors in mice. Mechanistically, our results demonstrate that orally administered SMG not only rebalanced hippocampal pro- and anti-inflammatory cytokines (suppressing TNF-α while upregulating IL-10) but also significantly inhibited the NLRP3 inflammasome-mediated pyroptotic pathway, as evidenced by reduced IL-1β expression and decreased expression of GSDMD and microglial activation markers (CD68/CD86). Immunofluorescence analysis confirmed that oral SMG suppressed IBA1+ microglial activation and attenuated pro-inflammatory phenotypic shifts. By systematically elucidating that oral SMG can concurrently target both neuroinflammatory and pyroptosis cascades, this study highlights a novel mechanism of action and provides strong evidence for developing SMG as a dietary-based or orally active neuroprotective agent for inflammation-related depression.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"138 ","pages":"Article 107170"},"PeriodicalIF":4.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146057408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular and microstructural cues for starch digestive heterogeneity in Indian pearl millet (Pennisetum Glaucum) 印度珍珠粟（Pennisetum Glaucum）淀粉消化异质性的分子和微观结构线索

IF 4 2区农林科学

Journal of Functional Foods Pub Date : 2026-03-01 Epub Date: 2026-02-17 DOI: 10.1016/j.jff.2026.107208

Sneha Pandey , Deepanyeta Goswami , T. Vinutha , Suneha Goswami , Ranjeet Ranjan Kumar , Sumer Pal Singh , Shalini Gaur Rudra , Manish Kumar Singh , Tara Satyavathi , Aiswarya Girija , Sijo Joseph Thandapilly , Veda Krishnan

{"title":"Molecular and microstructural cues for starch digestive heterogeneity in Indian pearl millet (Pennisetum Glaucum)","authors":"Sneha Pandey , Deepanyeta Goswami , T. Vinutha , Suneha Goswami , Ranjeet Ranjan Kumar , Sumer Pal Singh , Shalini Gaur Rudra , Manish Kumar Singh , Tara Satyavathi , Aiswarya Girija , Sijo Joseph Thandapilly , Veda Krishnan","doi":"10.1016/j.jff.2026.107208","DOIUrl":"10.1016/j.jff.2026.107208","url":null,"abstract":"<div><div>Pearl millet (PM) is a nutrient-rich, climate-resilient cereal with potential for low-glycemic food applications. This study examined molecular and microstructural determinants of <em>in vitro</em> starch digestibility in 11 PM genotypes. Variation in starch composition (amylose: 18.27–27.68%; amylopectin: 30.62–51.12%) influenced the distribution of digestible fractions. Rapidly digestible starch ranged from 26.32% (HHB-67 Improved) to 44.74% (PC-701), while slowly digestible starch varied from 14.65% (Pusa-1803) to 27.44% (Chanana Bajri) and was negatively correlated with predicted glycemic index (pGI: 54.63–58.87; <em>r</em> = −0.633). Rheological analysis showed an inverse relationship between peak viscosity and pGI (<em>r</em> = −0.828), suggesting restricted starch gelatinization reduces enzymatic accessibility. X-ray diffraction revealed that higher crystallinity (18.44–26.97%) was also associated with lower pGI (<em>r</em> = −0.788). The Principal Component Analysis grouped Chanana Bajri, PC-701 and 86M94 as structurally compact, slowly digestible types, while Dhodsar Local and Pusa-1803 aligned with higher RDS and pGI, confirming microstructure-governed digestibility variation.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"138 ","pages":"Article 107208"},"PeriodicalIF":4.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147385555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Polysaccharides from perilla (Perilla frutescens L.) seed induce mitochondrial apoptosis in HCT-116 cells via BID - BAX axis 紫苏多糖通过BID - BAX轴诱导HCT-116细胞线粒体凋亡

IF 4 2区农林科学

Journal of Functional Foods Pub Date : 2026-03-01 Epub Date: 2026-02-14 DOI: 10.1016/j.jff.2026.107209

Yan-Ling Zhang , Qi-Cong Chen , Wei-Le Liu , Shou-Bin Huang , Yu-Tai Li , Wen Zhong , Qiang Liu , Huo-Ji Chen , Cui-Ping Jiang , Shao-Wei Zheng , Chun-Yan Shen

{"title":"Polysaccharides from perilla (Perilla frutescens L.) seed induce mitochondrial apoptosis in HCT-116 cells via BID - BAX axis","authors":"Yan-Ling Zhang , Qi-Cong Chen , Wei-Le Liu , Shou-Bin Huang , Yu-Tai Li , Wen Zhong , Qiang Liu , Huo-Ji Chen , Cui-Ping Jiang , Shao-Wei Zheng , Chun-Yan Shen","doi":"10.1016/j.jff.2026.107209","DOIUrl":"10.1016/j.jff.2026.107209","url":null,"abstract":"<div><div>Two homogeneous polysaccharides, PFSP-1 and PFSP-3, were isolated from perilla (<em>Perilla frutescens</em> L.) seeds (PFSP) and exhibited significant structural differences. Molecular weights of PFSP-1 and PFSP-3 were 3.58 × 10<sup>4</sup> Da and 1.04 × 10<sup>7</sup> Da, respectively. Monosaccharide composition analysis indicated that PFSP-1 consisted of fucose, glucose, and galactose in a molar ratio of 1.36:1.94:1, whereas PFSP-3 was composed of fucose, xylose, glucose, and galactose at a ratio of 3.63:1.21:19.62:1. Morphological observations revealed that PFSP-1 displayed irregular flocculent formations with smooth surfaces, while PFSP-3 showed continuous sheet-like structures. A comparison of bioactivity revealed that PFSP-1, but not PFSP-3, significantly inhibited the proliferation of HCT-116 colon cancer cells. PFSP-1 potently induced apoptosis as evidenced by increased TUNEL positivity, caspase-9/3 activation, and mitochondrial membrane potential collapse. Transcriptomics and validation identified BID and BAX as key mediators. Further validation confirmed that PFSP-1 promoted BID expression, facilitated BAX activation, and triggered mitochondrial dysfunction, ultimately leading to the execution of apoptosis via the caspase-9/caspase-3 cascade. These findings collectively demonstrate that structural variations, particularly in monosaccharide composition and molecular architecture, critically govern the differential anti-colon cancer activity of perilla seed polysaccharides.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"138 ","pages":"Article 107209"},"PeriodicalIF":4.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147385623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Plant-based functional foods for healthy aging: current trends, bioactive compounds, and future perspectives 健康衰老的植物性功能食品：当前趋势、生物活性化合物和未来展望

IF 4 2区农林科学

Journal of Functional Foods Pub Date : 2026-03-01 Epub Date: 2026-02-03 DOI: 10.1016/j.jff.2026.107155

Mangalambika Balaji , Rahul Vashishth , Utpal Das

{"title":"Plant-based functional foods for healthy aging: current trends, bioactive compounds, and future perspectives","authors":"Mangalambika Balaji , Rahul Vashishth , Utpal Das","doi":"10.1016/j.jff.2026.107155","DOIUrl":"10.1016/j.jff.2026.107155","url":null,"abstract":"<div><div>Plant-based functional foods are gaining recognition for promoting healthy aging, enhancing skin and cognitive health, and addressing modern dietary needs through bioactive compounds. Rich in antioxidants, polyphenols, and dietary fibers, these foods help prevent chronic diseases, improve digestive health, and support overall wellness. Consumer interest is driven by growing health awareness and personalized nutrition goals. Key plant-derived ingredients such as phenolic compounds, dietary fibers, plant proteins, phytosterols, and omega-3 fatty acids confer diverse functional benefits. Bioactive compounds with anti-aging potential such as carotenoids, polyphenols, and probiotics, have been shown to support skin integrity and cognitive function. However, challenges such as sensory acceptance, nutrient bioavailability, and regulatory barrier remain. This review examines current consumer trends, key bioactive ingredients, and technological advancements in plant-based functional foods. It emphasizes the need for continued research to enhance efficacy and acceptance, highlights their potential as essential contributors to sustainable health and future nutrition strategies.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"138 ","pages":"Article 107155"},"PeriodicalIF":4.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146171611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0