{"title":"Seroprevalence of infectious bursal disease and its associated risk factors in Ethiopia: a systematic review and meta-analysis.","authors":"Solomon Lulie Abey, Gashaw Getaneh Dagnaw, Anmaw Shite Abat, Asnakew Mulaw Berihun, Zewdu Seyoum Tarekegn, Takele Adugna, Abebe Belete Bitew","doi":"10.1080/03079457.2024.2393613","DOIUrl":"10.1080/03079457.2024.2393613","url":null,"abstract":"<p><p>The poultry population is an integral part of Ethiopia's Gross Domestic Product (GDP) but, due to various infectious diseases such as infectious bursal disease (IBD), the expected economic impact in the country remains limited. The status of the disease in Ethiopia is obscured; thus, a systematic review and meta-analysis were employed to estimate the overall pooled prevalence of IBD in Ethiopia. Meta-analysis was conducted to determine the effects of each identified risk factor, while meta-regression and sub-group analysis were employed to assess the relationship between study-level covariates and effect size. The pooled prevalence of IBD in Ethiopia was 69.4% (95% CI 30.7-96.2), while the pooled logit prevalence was 0.94 (95% CI: 0.68-1.20) with significant inter-study variance (<i>Q</i> test = 948.28, df = 43, <i>P</i> < 0.001; <i>τ</i><sup>2</sup> = 0.71, <i>I</i><sup>2 </sup>= 95.47%). A small-study effect was detected in the regression-based Egger test (Prob > |<i>z</i>| < 0.0001). Significant variation was observed among different groups such as sex, age, breed, and type of farm of the chickens. The effect size for the study period from 2018 to 2021 was significantly lower by -0.204 compared to the study period from 2009 to 2015 (<i>P</i> < 0.0001. In conclusion, the IBD pooled prevalence estimate is high, even though the number of studies in the country is insufficient. The high prevalence of the disease requires prompt attention from all stakeholders in the sector to bring it under control through comprehensive disease prevention and control intervention strategies.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":" ","pages":"108-119"},"PeriodicalIF":2.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141999318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Avian PathologyPub Date : 2025-02-01Epub Date: 2024-09-18DOI: 10.1080/03079457.2024.2398028
Mohammad Ali Shamshirgaran, Mehdi Golchin
{"title":"Necrotic enteritis in chickens: a comprehensive review of vaccine advancements over the last two decades.","authors":"Mohammad Ali Shamshirgaran, Mehdi Golchin","doi":"10.1080/03079457.2024.2398028","DOIUrl":"10.1080/03079457.2024.2398028","url":null,"abstract":"<p><p><b>ABSTRACT</b>Necrotic enteritis (NE) is a severe gastrointestinal disease that poses a significant threat to poultry, leading to progressive deterioration of the small intestine, reduced performance, and increased mortality rates, causing economic losses in the poultry industry. The elimination of antimicrobial agents from chicken feed has imposed a need to explore alternative approaches for NE control, with vaccination emerging as a promising strategy to counteract the detrimental consequences associated with NE. This comprehensive review presents an overview of the extensive efforts made in NE vaccination from 2004 to 2023. The review focuses on the development and evaluation of vaccine candidates designed to combat NE. Rigorous evaluations were conducted in both experimental chickens and broiler chickens, the target population, to assess the vaccines' capacity to elicit an immune response and provide substantial protection against toxin challenges and experimental NE infections. The review encompasses the design of vaccine candidates, the antigens employed, <i>in vivo</i> immune responses, and the efficacy of these vaccines in protecting birds from experimental NE infection. This review contributes to the existing knowledge of NE vaccination strategies, offering valuable insights for future research and development in this field.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":" ","pages":"1-26"},"PeriodicalIF":2.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142071859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nobiletin, an activator of the pyruvate kinase isozyme M1/M2 protein, upregulated the glycolytic signalling pathway and alleviated depressive-like behaviour caused by artificial light exposure at night in zebrafish.","authors":"Meng-Ling Zhang, Xiao-Peng Li, Li-Fang Gao, Jian Liu, Zi-Jun Bi, Yu-Han Miao, Yang Shan, Huan-Ling Yu","doi":"10.1016/j.foodchem.2024.141328","DOIUrl":"10.1016/j.foodchem.2024.141328","url":null,"abstract":"<p><p>We established a zebrafish model of depression-like behaviour induced by exposure to artificial light at night (ALAN) and found that nobiletin (NOB) alleviated depression-like behaviour. Subsequently, based on the results of a 24-h free movement assay, clock gene expression and brain tissue transcriptome sequencing, the glycolysis signalling pathway was identified as a potential target through which NOB exerted antidepressant effects. Using the ALAN zebrafish model, we found that supplementation with exogenous L-lactic acid alleviated depressive-like behaviour. Molecular docking and molecular dynamics simulations revealed an inter-molecular interaction between NOB and the pyruvate kinase isozyme M1/M2 (PKM2) protein. We then used compound 3 k to construct a zebrafish model in which PKM2 was inhibited. Our analysis of this model suggested that NOB alleviated depression-like behaviour via inhibition of PKM2. In summary, NOB alleviated depressive-like behaviour induced by ALAN in zebrafish via targeting of PKM2 and activation of the glycolytic signalling pathway.</p>","PeriodicalId":318,"journal":{"name":"Food Chemistry","volume":"463 Pt 2","pages":"141328"},"PeriodicalIF":8.5,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142277864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Insights into the molecular mechanisms of lipid metabolism of air-dried goose on the formation of flavor substances by co-inoculation of lactic acid bacteria and staphylococcus based on GC-MS and lipidomics.","authors":"Qiongfang Cao, Xiankang Fan, Jue Xu, Zihang Shi, Wei Wang, Zhaoshan Wang, Yangying Sun, Qiang Xia, Changyu Zhou, Daodong Pan","doi":"10.1016/j.foodchem.2024.141388","DOIUrl":"10.1016/j.foodchem.2024.141388","url":null,"abstract":"<p><p>Microorganisms and lipids always interact in a complex way in the meat matrix, which affects the flavor of meat products. This study aimed to examine the impact of complex fermentation with distinct microorganisms on fat oxidation, lipid profile, and the biochemical pathways involved in flavor substance formation. GC-MS analysis revealed that 12 key volatile substances including hexanal, heptanal, benzeneacetaldehyde, decanal, 1-nonanol, 1-hexanol, 1-octen-3-ol were responsible for the flavor variations in geese. Lipidomics analysis of three groups identified 440 lipid molecules, with triglycerides and glycerophospholipids being the most abundant categories. Spearman correlation analysis showed that 4 key volatile substances exhibited positive correlations with lysophosphatidylethanolamines, lysophosphatidycholines, phosphatidylcholines, phosphatidylethanolamines. The data presented herein facilitate an understanding of the lipid dynamics during fermentation and provide insights into the potential for controlling the flavor quality of fermented air-dried meat products.</p>","PeriodicalId":318,"journal":{"name":"Food Chemistry","volume":"463 Pt 2","pages":"141388"},"PeriodicalIF":8.5,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142338220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Food ChemistryPub Date : 2025-01-15Epub Date: 2024-09-17DOI: 10.1016/j.foodchem.2024.141290
Sihan Ma, Aiqian Ye, Harjinder Singh, Alejandra Acevedo-Fani
{"title":"Heat-induced interactions between microfluidized hemp protein particles and caseins or whey proteins.","authors":"Sihan Ma, Aiqian Ye, Harjinder Singh, Alejandra Acevedo-Fani","doi":"10.1016/j.foodchem.2024.141290","DOIUrl":"10.1016/j.foodchem.2024.141290","url":null,"abstract":"<p><p>The rising demand for sustainable proteins leads to increased interest in plant proteins like hemp protein (HP). However, commercial HP's poor functionality, including heat aggregation, limit its use. This study explored the heat-induced interactions of hemp protein particles (HPPs) with milk proteins, specifically whey proteins and caseins. Using various analysis techniques-static light scattering, TEM, SDS electrophoresis, surface hydrophobicity, and free sulfhydryl content-results showed that co-heating HPPs with whey protein isolate (WPI) or sodium caseinate (NaCN) at 95 °C for 20 min reduced HPPs aggregation. HPPs/WPI particles had a d<sub>4,3</sub> of ∼3.8 μm, while HPPs/NaCN were ∼1.9 μm, compared to ∼27.5 μm for HPPs alone. SDS-PAGE indicated that whey proteins irreversibly bound to HPPs, through disulfide bonds, whereas casein bound reversibly, possibly involving the chaperone-like property of casein. This study proposes possible mechanisms by which HPPs interact with milk proteins and impact protein aggregation. This may provide opportunities for developing hybrid protein microparticles.</p>","PeriodicalId":318,"journal":{"name":"Food Chemistry","volume":"463 Pt 2","pages":"141290"},"PeriodicalIF":8.5,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142277861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An environmentally benign process to synthesize vanillin and other substituted phenyl aldehydes using natural phenylpropenes.","authors":"Sarita Singh, Swati Singh, Asha Budakoti, Neha Kumari, Ram Swaroop Verma, Arvind Singh Negi, Karuna Shanker, Sudeep Tandon, Alok Kalra, Atul Gupta","doi":"10.1016/j.foodchem.2024.141320","DOIUrl":"10.1016/j.foodchem.2024.141320","url":null,"abstract":"<p><p>The limited vanillin (3a) production from plant sources requires identifying some renewable and sustainable approaches for its synthesis. This study aimed to develop an efficient, eco-friendly process for synthesizing vanillin (3a) from eugenol (1a) and eugenol-rich essential oils. The chemical methodology for vanillin (3a) synthesis involved base-mediated isomerization of eugenol (1a) to isoeugenol (2a), followed by OsO<sub>4</sub>/NaIO<sub>4</sub> mediated oxidation of isoeugenol to vanillin (3a) using different additives such 1,4-diazabicyclo[2.2.2]octane (DABCO) and substituted pyridines in reusable environment-friendly solvents. Use of 2,6-dimethylpyridine and 2,6-dimethylpyridine N-oxide as additives in the oxidation step offered a significantly higher product yield (vanillin 3a, 70 %). The process synthesized vanillin (3a) irrespective of the cis/ trans stereochemistry of isoeugenol (2a). The peculiarity of the method relates to converting eugenol (1a) to vanillin (3a) without phenolic group protection, which offers step economy. Besides efficient vanillin (3a) synthesis, the process's general implications involve converting other naturally occurring phenylpropenes or phenylpropenes-enriched oils to the corresponding phenyl aldehydes (59-82 % yield).</p>","PeriodicalId":318,"journal":{"name":"Food Chemistry","volume":"463 Pt 3","pages":"141320"},"PeriodicalIF":8.5,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142338223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Food ChemistryPub Date : 2025-01-15Epub Date: 2024-09-17DOI: 10.1016/j.foodchem.2024.141331
Qiuhui Xu, Jie Wang, Dan Wang, Xin Lv, Li Fu, Ping He, Desheng Mei, Hong Chen, Fang Wei
{"title":"Comprehensive physicochemical indicators analysis and quality evaluation model construction for the post-harvest ripening rapeseeds.","authors":"Qiuhui Xu, Jie Wang, Dan Wang, Xin Lv, Li Fu, Ping He, Desheng Mei, Hong Chen, Fang Wei","doi":"10.1016/j.foodchem.2024.141331","DOIUrl":"10.1016/j.foodchem.2024.141331","url":null,"abstract":"<p><p>Rapeseed (Brassica napus L.) is the second largest globally cultivated oil crop, but the effects of post-harvested ripening on rapeseed quality is unclear and unpredictable. This study reveals the relationship between post-harvest ripening periods (PHR) and physicochemical quality of different rapeseed cultivars using comprehensive physicochemical indicators analysis. The results indicate that PHR led to a gradual decrease in chlorophyll, carotenoid and moisture content but continually increased oil and total phenol content (TPC). Besides, 295 lipid molecules from 13 lipid subclasses were identified, revealing that the relative content of triacylglycerol (TG) was progressively increased while diacylglycerol (DG) demonstrated a consistent decline throughout the PHR. Correlation analysis, hierarchical cluster analysis (HCA) and principal component analysis (PCA) were employed to construct and verify the comprehensive quality evaluation model for rapeseeds in PHR. This paper develops a comprehensive quality evaluation model for post-harvest ripening rapeseeds and advances the development of agricultural products.</p>","PeriodicalId":318,"journal":{"name":"Food Chemistry","volume":"463 Pt 2","pages":"141331"},"PeriodicalIF":8.5,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142277856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Food ChemistryPub Date : 2025-01-15Epub Date: 2024-09-16DOI: 10.1016/j.foodchem.2024.141289
Li Xiao, Jinxin Liu, Marti Z Hua, Xiaonan Lu
{"title":"Rapid determination of total phenolic content and antioxidant capacity of maple syrup using Raman spectroscopy and deep learning.","authors":"Li Xiao, Jinxin Liu, Marti Z Hua, Xiaonan Lu","doi":"10.1016/j.foodchem.2024.141289","DOIUrl":"10.1016/j.foodchem.2024.141289","url":null,"abstract":"<p><p>Total phenolic content (TPC) and antioxidant capacity of maple syrup were determined using Raman spectroscopy and deep learning. TPC was determined by Folin-Ciocalteu assay, while the antioxidant capacity was measured by 2,2-diphenyl-1picrylhydrazyl (DPPH) assay, oxygen radical absorbance capacity (ORAC) assay, and ferric reducing antioxidant power (FRAP) assay. A total of 360 spectra were collected from 36 maple syrup samples of different colours (dark, amber, light) by both benchtop and portable Raman spectrometers. These spectra were used to establish predictive models for assessing the antioxidant profiles of maple syrup. Deep learning models developed along with portable Raman spectroscopy exhibited comparable predictive performance to those developed along with benchtop Raman spectroscopy. Base on the spectral dataset collected using portable Raman spectroscopy, the developed deep learning models exhibited low RMSEs (root mean square errors, 7.2-17.9 % of mean reference values), low MAEs (mean absolute errors, 5.2-13.1 % of mean reference values) and high R<sup>2</sup> values (>0.88). The results showed a great goodness of fit and accuracy for predicting the antioxidant profiles of maple syrup, indicating the potential of using portable Raman spectrometer for on-site analysis of antioxidant profiles of maple syrup.</p>","PeriodicalId":318,"journal":{"name":"Food Chemistry","volume":"463 Pt 2","pages":"141289"},"PeriodicalIF":8.5,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142277865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Food ChemistryPub Date : 2025-01-15Epub Date: 2024-09-17DOI: 10.1016/j.foodchem.2024.141329
Yingxin Liu, Fangliang Li, Tao Fei, Xue Lin, Lu Wang, Zhonghua Liu
{"title":"Natural α-glucosidase inhibitors from Aquilaria sinensis leaf-tea: Targeted bio-affinity screening, identification, and inhibition mechanism.","authors":"Yingxin Liu, Fangliang Li, Tao Fei, Xue Lin, Lu Wang, Zhonghua Liu","doi":"10.1016/j.foodchem.2024.141329","DOIUrl":"10.1016/j.foodchem.2024.141329","url":null,"abstract":"<p><p>Aquilaria sinensis leaves have long been consumed as a popular replacement tea for lowering postprandial blood glucose levels, but their specific functional components remain unclear. In this study, Aquilaria sinensis leaf-tea 70 % ethanol extract (ALTE) exhibited excellent anti-α-glucosidase activity (IC<sub>50</sub> = 6.93 ± 1.91 μg/mL) and promoted glucose consumption ability in 3 T3-L1 preadipocyte cells. Subsequently phenolic compositions of ALTE were identified for the first time. After that, five potential α-glucosidase inhibitors (α-GIs) including cynaroside-3,5-diglucose, malvidin 3-glucose, epicatechin, epigallocatechin gallate, and dihydromyricetin in ALTE were screened using a targeted bio-affinity ultrafiltration-HPLC/MS method. Moreover, these five α-GIs all showed good anti-α-glucosidase effects and glucose consumption-promoting ability. Furthermore, the binding properties and inhibition mechanisms of five α-GIs to α-glucosidase were further analyzed via enzyme inhibition kinetics, molecular docking, and molecular dynamics simulation. This study confirms that Aquilaria sinensis leaf-tea is effective in preventing post-hyperglycemia in vitro models, suggesting potential for future research in human trials.</p>","PeriodicalId":318,"journal":{"name":"Food Chemistry","volume":"463 Pt 2","pages":"141329"},"PeriodicalIF":8.5,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142277862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}