Journal of Food and Drug Analysis最新文献

An optical fiber caffeine sensor using a molecularly imprinted polymethacrylic acid membrane coated on optical fiber surface as a transducer. 一种采用分子印迹聚甲基丙烯酸膜包覆在光纤表面作为传感器的光纤咖啡因传感器。

IF 3.3 3区农林科学

Journal of Food and Drug Analysis Pub Date : 2026-09-01 DOI: 10.38212/2224-6614.3562

Josiah W Miller, Jason D McCaslin, Shiquan Tao

引用次数: 0

Benefits and risks of consuming Cannabis sativa L. in food. 食用食物中的大麻的益处和风险。

IF 3.3 3区农林科学

Journal of Food and Drug Analysis Pub Date : 2026-09-01 DOI: 10.38212/2224-6614.3578

Ewa Matyjaszczyk, Maria Śmiechowska

{"title":"Benefits and risks of consuming Cannabis sativa L. in food.","authors":"Ewa Matyjaszczyk, Maria Śmiechowska","doi":"10.38212/2224-6614.3578","DOIUrl":"10.38212/2224-6614.3578","url":null,"abstract":"Cannabis sativa L. or hemp is a cosmopolitan, multi-purpose plant and area of its cultivation has been growing in recent years. Its public perception is influenced by potential to produce narcotic substances. However, hemp seed can be a valuable source of nutrients for humans and may be of particular interest in more sustainable food consumption patterns, including vegetarian and flexitarian diets. The paper presents benefits and risks of hemp seeds in case of their consumption in food. Low cannabinoids varieties are considered only. The biological activity of cannabinoids and related effects are considered out of scope of the study. Nutritional value of hemp seeds regarding content of amino acids is comparable to the value of egg whites and soya. Oil is a source of two essential fatty acids: linoleic acid and alpha-linolenic acid in a desirable ratio of 3:1. Hemp seeds are also a source of minerals, vitamins and carbohydrates, including fiber. The most characteristic hazardous properties of hemp are ability to accumulate toxic heavy metals and produce anti-nutritional substances. Breeding hemp to reduce the anti-nutritional compounds content may be promising in view of its growing popularity as a food source.","PeriodicalId":358,"journal":{"name":"Journal of Food and Drug Analysis","volume":"34 3","pages":"299-310"},"PeriodicalIF":3.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13592844/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149056757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluating the potential of Cajanus cajan (L.) Millsp. Root to improve atopic dermatitis with different anti-inflammatory models and active compounds. 菜豆（Cajanus cajan）潜力评价Millsp。根治特应性皮炎用不同的抗炎模型和活性化合物。

IF 3.3 3区农林科学

Journal of Food and Drug Analysis Pub Date : 2026-09-01 DOI: 10.38212/2224-6614.3591

Shu-Er Yang, Xiang-Ming Cai, Yu-Wen Chu, Jen-Chieh Tsai, Mey-Fann Lee, Tuzz-Ying Song

引用次数: 0

Gut microbiota-mediated modulation of circadian rhythms: Physiological and molecular impacts of dietary composition and feeding time. 肠道微生物群介导的昼夜节律调节：饮食组成和喂养时间的生理和分子影响。

IF 3.3 3区农林科学

Journal of Food and Drug Analysis Pub Date : 2026-09-01 DOI: 10.38212/2224-6614.3596

Yen-Chun Koh, Chun-Che Chang, Min-Hsiung Pan

{"title":"Gut microbiota-mediated modulation of circadian rhythms: Physiological and molecular impacts of dietary composition and feeding time.","authors":"Yen-Chun Koh, Chun-Che Chang, Min-Hsiung Pan","doi":"10.38212/2224-6614.3596","DOIUrl":"10.38212/2224-6614.3596","url":null,"abstract":"Circadian rhythms regulate fundamental aspects of physiology and behavior. The disruption of circadian rhythms has been associated with metabolic disorders, cardiovascular disease, obesity, and impaired immune function. Feeding behavior and gut microbiota represent two essential nodes within this regulatory network, as both are highly responsive to environmental cues such as diet composition and sleep-wake cycles. Research has shown that high-fat diets, excessive fructose, and chronic alcohol consumption perturb peripheral circadian rhythms and impair metabolic pathways, contributing to obesity and insulin resistance. Conversely, dietary interventions such as time-restricted feeding and macronutrient-specific entrainment can restore rhythmic gene expression and prevent metabolic pathologies. The gut microbiota plays a central role in mediating these effects through its diurnal oscillations in community composition and metabolite production, particularly short-chain fatty acids, which act as systemic cues for host circadian clocks. Disruption of microbial rhythmicity, whether through irregular eating schedules, jet lag, or environmental pollutants, can exacerbate circadian misalignment and metabolic dysfunction. Recent findings highlight a bidirectional relationship between the host circadian system and the microbiota, underscoring their interdependence in maintaining metabolic homeostasis and gastrointestinal integrity. Although preclinical models have produced mechanistic insights, the translation to humans remains limited by methodological variability and incomplete characterization of signaling pathways. This review synthesizes the current knowledge on diet-microbiota-circadian interactions and discusses potential therapeutic strategies, including dietary modulation and natural products, to mitigate circadian misalignment and its associated health risks.","PeriodicalId":358,"journal":{"name":"Journal of Food and Drug Analysis","volume":"34 3","pages":"311-330"},"PeriodicalIF":3.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13592840/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149056689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A target-responsive and signal-amplified DNA hydrogel biosensor for visual and quantitative detection of aflatoxin B1. 用于黄曲霉毒素B1视觉和定量检测的目标响应和信号扩增DNA水凝胶生物传感器。

IF 3.3 3区农林科学

Journal of Food and Drug Analysis Pub Date : 2026-09-01 DOI: 10.38212/2224-6614.3608

Haojie Du, Haoyue Liu, Yongshuai Li, Shiyi Wei, Xinning Wang, Yunxuan Weng, Xiaoying Zhao

{"title":"A target-responsive and signal-amplified DNA hydrogel biosensor for visual and quantitative detection of aflatoxin B1.","authors":"Haojie Du, Haoyue Liu, Yongshuai Li, Shiyi Wei, Xinning Wang, Yunxuan Weng, Xiaoying Zhao","doi":"10.38212/2224-6614.3608","DOIUrl":"10.38212/2224-6614.3608","url":null,"abstract":"Aflatoxin B1 (AFB1) poses a severe threat to food safety due to its potent carcinogenicity. To address the need for rapid and on-site detection, this study developed a colorimetric biosensor based on an AFB1-responsive DNA aptamercross-linked sodium alginate hydrogel. Gold nanoparticles (AuNPs) were encapsulated within the hydrogel as a visual signal reporter. The sensing mechanism relies on target-induced dissociation of aptamer crosslinkers, leading to hydrogel disintegration and release of AuNPs. The hydrogel formulation was optimized regarding sodium alginate concentration and crosslinking conditions. To enhance sensitivity, an Exonuclease I (Exo I)-triggered target recycling strategy was implemented, which amplifies hydrogel network disruption by cleaving the aptamer-target complex and recycling the aptamer. The sensor demonstrated a linear detection range of 0-50 μM, with a detection limit of 12.9 nM, and exhibited high selectivity towards AFB1. This work presents a sensitive, visually readable, and portable platform for mycotoxin detection in food safety applications.","PeriodicalId":358,"journal":{"name":"Journal of Food and Drug Analysis","volume":"34 3","pages":"432-439"},"PeriodicalIF":3.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13592843/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149056710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Garambullo (Myrtillocactus geometrizans) reduces cell viability via apoptosis and inhibits colony formation in HT-29 and SW480 colon cancer cell lines. Garambullo （Myrtillocactus geometrizans）通过凋亡降低HT-29和SW480结肠癌细胞系的细胞活力，抑制集落形成。

IF 3.3 3区农林科学

Journal of Food and Drug Analysis Pub Date : 2026-09-01 DOI: 10.38212/2224-6614.3599

López-Alvarez Guadalupe Soledad, Gutierrez-Silerio Gloria Yareli, García-Solís Pablo, Morales-Bárcenas Rocio, Sánchez-Pérez Yesennia, Hernández-Puga Ana Gabriela, Vergara-Castañeda Haydé Azeneth

{"title":"Garambullo (Myrtillocactus geometrizans) reduces cell viability via apoptosis and inhibits colony formation in HT-29 and SW480 colon cancer cell lines.","authors":"López-Alvarez Guadalupe Soledad, Gutierrez-Silerio Gloria Yareli, García-Solís Pablo, Morales-Bárcenas Rocio, Sánchez-Pérez Yesennia, Hernández-Puga Ana Gabriela, Vergara-Castañeda Haydé Azeneth","doi":"10.38212/2224-6614.3599","DOIUrl":"10.38212/2224-6614.3599","url":null,"abstract":"Garambullo (Myrtillocactus geometrizans) is a Mexican wild fruit rich in phytochemicals. In this study, freeze-dried garambullo was subjected to in vitro gastrointestinal digestion and fermentation. The resulting fermented extract of garambullo (FEG) was evaluated for its effects on cell viability in HT-29 and SW480 CRC cell lines using MTT assays. After 24 h of treatment, FEG exhibited IC50 values of 2985 μg/mL and 3200 μg/mL in HT-29 and SW480 cells, respectively, indicating a significant reduction in cell viability compared to the control group. This reduction was further confirmed by flow cytometry, which revealed increased late apoptosis and necrosis in HT-29 cells, and a pronounced increase of necrosis in SW480 cells treated with FEG. Molecular docking simulations further supported these findings, demonstrating that butyric acid, a metabolite identified in FEG, demonstrates energetically favorable interactions with Caspase-3 (ΔG: -5.41 kcal/mol) and RIPK1 (ΔG: -5.18 kcal/mol), suggesting potential multi-pathway involvement in apoptotic and necrosis-associated cell death. Furthermore, the colony-forming ability of these CRC cell lines was assessed using 3D culture assays. After 14 days, FEG reduced colony formation in SW480 cells, with complete suppression observed at 149 μg/mL. Notably, HT-29 cells exhibited greater sensitivity, as no colonies were detected at any of the tested concentrations (≥37 μg/mL). These findings indicate that FEG exerts significant anti-proliferative, proapoptotic, and anti-clonogenic effects in CRC cell lines, supporting its potential as a candidate for further investigation in therapeutic or preventive strategies.","PeriodicalId":358,"journal":{"name":"Journal of Food and Drug Analysis","volume":"34 3","pages":"331-343"},"PeriodicalIF":3.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13592839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149056705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimization of gemifloxacin immediate-release tablets using quality by design. 设计优化吉氟沙星速释片质量。

IF 3.3 3区农林科学

Journal of Food and Drug Analysis Pub Date : 2026-09-01 DOI: 10.38212/2224-6614.3600

Jong Woo Kim, Jae Seon Kang, Yeon Hee Kim, Kang Min Kim

{"title":"Optimization of gemifloxacin immediate-release tablets using quality by design.","authors":"Jong Woo Kim, Jae Seon Kang, Yeon Hee Kim, Kang Min Kim","doi":"10.38212/2224-6614.3600","DOIUrl":"10.38212/2224-6614.3600","url":null,"abstract":"The objective of this study is to determine the design space (DS) for a dissolution-enhanced gemifloxacin immediate-release (IR) tablet incorporating hydroxypropyl-β-cyclodextrin (HPCD) for improved solubility, utilizing a quality by design (QbD) approach. Based on the preliminary studies, hardness, friability, disintegration time, assay, content uniformity, and dissolution rate were identified as the critical quality attributes (CQAs) for optimization. Through the initial risk assessment, crospovidone, main compression force, and the amount of granulating fluid were identified as factors influencing the CQAs, and a 23 + 3 full factorial design of experiments (DoE) was conducted for optimization. According to the analysis of variance (ANOVA), both main compression force (p = 0.004) and the amount of granulating fluid (p = 0.001) significantly affected hardness. While the amount of granulating fluid was established as a primary factor influencing disintegration time (p = 0.001) and dissolution rate (p = 0.006). The other factors did not show a statistically significant impact on the remaining CQAs. The optimized ranges obtained from this study were as follows: crospovidone, 5.72-7.99%; main compression force, 1707.5-2372.3 kgf; and amount of granulating fluid, 5.36-6.12 mL. A 23 + 3 full-factorial design of experiments (DoE) was applied to determine the relationship between independent and dependent variables, and a high-quality IR tablet meeting all predefined CQA criteria [hardness (18.0-22.0 kp), friability (≤0.5%), disintegration time (16.0-20.0 min), assay (95.0-105.0%), content uniformity (AV ≤ 5), and dissolution similarity (f2 ≥ 50)] was developed through the systematic optimization of formulation and manufacturing processes.","PeriodicalId":358,"journal":{"name":"Journal of Food and Drug Analysis","volume":"34 3","pages":"290-298"},"PeriodicalIF":3.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13592848/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149056696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Soybean fermentation broth alleviates indomethacin-induced gastric mucosal injury. 大豆发酵液减轻吲哚美辛所致胃黏膜损伤。

IF 3.3 3区农林科学

Journal of Food and Drug Analysis Pub Date : 2026-09-01 DOI: 10.38212/2224-6614.3601

Hsiao-Chi Wang, Yue-Jhu Chen, Hui-Yun Tsai, Jue-Liang Hsu, Yu-Kuo Chen

{"title":"Soybean fermentation broth alleviates indomethacin-induced gastric mucosal injury.","authors":"Hsiao-Chi Wang, Yue-Jhu Chen, Hui-Yun Tsai, Jue-Liang Hsu, Yu-Kuo Chen","doi":"10.38212/2224-6614.3601","DOIUrl":"10.38212/2224-6614.3601","url":null,"abstract":"Dietary strategies and plant-based fermented foods have attracted increasing interest for supporting gastrointestinal health, particularly under conditions of drug-induced mucosal stress. Soybean fermentation broth (SFB), a fermented soybean-derived product, may possess enhanced nutritional and functional properties through fermentation-associated generation of bioactive peptides and antioxidant metabolites. This study evaluated the gastroprotective effects of SFB in an indomethacin-induced gastric injury model in rats and investigated the underlying mechanisms. Indomethacin markedly induced gastric ulcer formation (16.61 ± 1.38 mm2), whereas SFB pretreatment significantly attenuated ulcer development in a dose-dependent manner, reducing ulcer area to 6.66 ± 0.98, 3.89 ± 0.63, and 1.46 ± 0.32 mm2 in low-, medium-, and high-dose groups, respectively (p < 0.05 vs. Vehicle). Histopathological examination revealed that SFB preserved epithelial integrity and reduced submucosal edema. SFB pretreatment significantly decreased lipid peroxidation, restored gastric glutathione content, and enhanced antioxidant enzyme activities, including glutathione peroxidase (GPx), glutathione reductase (GRd), superoxide dismutase (SOD), and catalase (CAT). Furthermore, SFB suppressed pro-inflammatory mediator expression and favorably modulated cyclooxygenase-1 (COX-1) and COX-2 expression, accompanied by restoration of prostaglandin E2 (PGE2) production. These findings indicate that SFB protects gastric mucosa against indomethacin-induced injury through coordinated regulation of oxidative stress, inflammatory signaling, and prostaglandin-mediated mucosal defense, supporting its potential as a functional fermented soybean product.","PeriodicalId":358,"journal":{"name":"Journal of Food and Drug Analysis","volume":"34 3","pages":"344-361"},"PeriodicalIF":3.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13592851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149056723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Plant by-products as a valuble source of natural antiglycemic compounds: Economic aspects and alternative raw material sources. 植物副产品作为天然降糖化合物的宝贵来源：经济方面和替代原料来源。

IF 3.3 3区农林科学

Journal of Food and Drug Analysis Pub Date : 2026-09-01 DOI: 10.38212/2224-6614.3587

Tatjana Đorđević, Jelena Vujetić, Isidora Dickov, Diandra Pintać Šarac

{"title":"Plant by-products as a valuble source of natural antiglycemic compounds: Economic aspects and alternative raw material sources.","authors":"Tatjana Đorđević, Jelena Vujetić, Isidora Dickov, Diandra Pintać Šarac","doi":"10.38212/2224-6614.3587","DOIUrl":"10.38212/2224-6614.3587","url":null,"abstract":"Plant by-products, often considered as waste in various agricultural and food processing industries, have emerged as a valuable source of natural antidiabetic or antihyperglycemic compounds. These compounds, derived from plant materials that would otherwise be discarded, have the potential to mitigate the global burden of diabetes and offer sustainable solutions for glycemic control. Prominent groups of natural antidiabetic compounds found in plant by-products are polyphenols, as well as bioactive proteins and peptides. In addition, agro-industrial residues such as wheat bran, oat husks, and fruit peels are excellent sources of carbohydrates that can be incorporated into functional foods to help manage diabetes. In addition to their antidiabetic potential, plant by-products contribute to sustainability and waste reduction by turning materials that would otherwise be discarded into valuable resources. Furthermore, the utilization of natural antidiabetic compounds from waste materials promises to improve diabetes management and promote a more sustainable food industry. The paper will address the valorization of agro-industrial by-products as natural sources of antiglycemic compounds, including an economic analysis and exploration of different raw material sources. It will present both the advantages and the key challenges associated with the biological activity, metabolism, bioavailability, and toxicological profiles of these compounds, as well as their economic and environmental implications. Furthermore, the review will highlight the prospects for automating this process through the application of artificial intelligence (AI), which may facilitate greater standardization and efficiency in future development.","PeriodicalId":358,"journal":{"name":"Journal of Food and Drug Analysis","volume":"34 3","pages":"235-252"},"PeriodicalIF":3.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13592847/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149056753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Emerging antifungal strategies against Candida albicans using metal-organic frameworks and novel therapeutics: Opportunities and challenges. 利用金属有机框架和新疗法对抗白色念珠菌的新兴抗真菌策略：机遇和挑战。

IF 3.3 3区农林科学

Journal of Food and Drug Analysis Pub Date : 2026-09-01 DOI: 10.38212/2224-6614.3585

Amanpreet Singh, Sandeep Kumar, Sehrabpreet Singh, Jeewanjot Singh

{"title":"Emerging antifungal strategies against Candida albicans using metal-organic frameworks and novel therapeutics: Opportunities and challenges.","authors":"Amanpreet Singh, Sandeep Kumar, Sehrabpreet Singh, Jeewanjot Singh","doi":"10.38212/2224-6614.3585","DOIUrl":"10.38212/2224-6614.3585","url":null,"abstract":"Candida albicans is an opportunistic fungal pathogen responsible for infections ranging from superficial mucosal disease to life-threatening systemic candidiasis, particularly in immunocompromised hosts. Its pathogenicity is enhanced by morphological plasticity, biofilm formation, and immune evasion, contributing to antifungal resistance. Limitations of existing antifungals have driven interest in emerging therapeutics. This review highlights strategies including metal-organic frameworks (MOFs), host-directed therapies (HDTs), CRISPR-Cas9 gene editing, and phytochemicals. MOFs offer high drug-loading capacity, controlled release, and enhanced penetration into biofilms, showing promise against drug-resistant strains. Selected phytochemicals demonstrate inhibitory effects on virulence traits such as hyphal formation and enzyme secretion. CRISPR-Cas9 enables functional genomic studies to identify and disrupt key pathogenicity genes, while HDTs aim to boost host immune responses. Additionally, the potential role of gut microbiota modulation in controlling C. albicans colonization is discussed. By integrating mechanistic insights with translational perspectives, this review provides a concise overview of emerging antifungal strategies, opportunities, and challenges with the potential to overcome current therapeutic limitations.","PeriodicalId":358,"journal":{"name":"Journal of Food and Drug Analysis","volume":"34 3","pages":"208-234"},"PeriodicalIF":3.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13592845/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149056703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0