Journal of Medical Ethics最新文献

Reflections on AI use declarations in JME manuscripts. 对JME手稿中AI使用声明的思考。

IF 4.4 2区哲学

Journal of Medical Ethics Pub Date : 2026-10-12 DOI: 10.1136/jme-2026-112675

Joshua Parker

引用次数: 0

Staging disease without illness: ethical issues of the Huntington's Disease Integrated Staging System (HD-ISS). 没有疾病的疾病分期：亨廷顿病综合分期系统（HD-ISS）的伦理问题。

IF 4.4 2区哲学

Journal of Medical Ethics Pub Date : 2026-10-09 DOI: 10.1136/jme-2025-111586

Max J Rensink, Bjørn M Hofmann

引用次数: 0

Ethics of opportunistic genomic screening in paediatrics: rethinking the risk-benefit ratio. 儿科机会性基因组筛查的伦理：重新思考风险-收益比。

IF 4.4 2区哲学

Journal of Medical Ethics Pub Date : 2026-10-05 DOI: 10.1136/jme-2026-111946

Emily Wheeler, Wayne Shelton, Gina Geis

{"title":"Ethics of opportunistic genomic screening in paediatrics: rethinking the risk-benefit ratio.","authors":"Emily Wheeler, Wayne Shelton, Gina Geis","doi":"10.1136/jme-2026-111946","DOIUrl":"https://doi.org/10.1136/jme-2026-111946","url":null,"abstract":"Genome-wide sequencing (GWS) has become an important tool in paediatric medicine, but it may uncover secondary findings (SFs) through opportunistic screening. The disclosure of adult-onset SFs in children, who cannot consent, raises ethical concerns regarding potential psychosocial harm and future autonomy. This paper examines whether parents should have the option to consent to opportunistic screening for actionable adult-onset conditions in their young children. Although there is consensus on disclosing actionable childhood-onset conditions, international guidelines remain divided on the return of adult-onset findings in paediatric populations. Drawing on existing literature, this paper argues for greater consensus around a risk-benefit framework centred on medical actionability. Emerging evidence suggests that the psychological harms associated with predictive testing may be less severe than previously assumed, while actionable findings may provide meaningful benefits to both the child and family. This paper further argues that upholding parental authority through shared decision-making and the concept of family benefit further supports offering parents the option to receive actionable adult-onset findings. In contrast, the disclosure of non-actionable adult-onset conditions is more difficult to justify given the absence of meaningful clinical benefit. In the absence of clear evidence of harm, a more family-centred approach that incorporates pretest counselling and ongoing support offers a practical framework for moving towards greater consensus on this long-debated issue.","PeriodicalId":16317,"journal":{"name":"Journal of Medical Ethics","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149109848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

MacIntyrean bioethics: reappraisal and outline of a research programme. 麦金太尔的生命伦理学：一个研究计划的重新评价和大纲。

IF 4.4 2区哲学

Journal of Medical Ethics Pub Date : 2026-10-05 DOI: 10.1136/jme-2026-112142

Morten Magelssen, Søren Holm, Eilev Hegstad, Skylar Christoffersen

引用次数: 0

What does AI health resource allocation make visible? AI健康资源分配使什么变得可见？

IF 4.4 2区哲学

Journal of Medical Ethics Pub Date : 2026-09-29 DOI: 10.1136/jme-2026-112504

Daniel Weissglass, Yantong Ou, Jiaming Li, Yawen Sun, Hollie Wright, Wenrui Wu, Xinwei Xu, Rui Yu, Hanting Zhang, Yihe Zhang

引用次数: 0

Beochaoineadh: grieving but not bereaved. Beochaoineadh：悲伤但不是失去亲人。

IF 4.4 2区哲学

Journal of Medical Ethics Pub Date : 2026-09-22 DOI: 10.1136/jme-2024-110610

Martha Finnegan

引用次数: 0

Germline genomic testing to assess the suitability of stem cell donors in the treatment of haematological malignancy: clinical ethics commentary. 生殖系基因组检测评估干细胞供体在血液恶性肿瘤治疗中的适用性：临床伦理评论。

IF 4.4 2区哲学

Journal of Medical Ethics Pub Date : 2026-09-22 DOI: 10.1136/jme-2025-111111

Helena Carley, Kate Sahan, Helen Hanson, Katie Snape, Sarah Westbury, Michael J Parker, Anneke M Lucassen

{"title":"Germline genomic testing to assess the suitability of stem cell donors in the treatment of haematological malignancy: clinical ethics commentary.","authors":"Helena Carley, Kate Sahan, Helen Hanson, Katie Snape, Sarah Westbury, Michael J Parker, Anneke M Lucassen","doi":"10.1136/jme-2025-111111","DOIUrl":"10.1136/jme-2025-111111","url":null,"abstract":"The increasing integration of genomic medicine into routine medical care brings to light issues of complexity and uncertainty in the interpretation of genetic variation.We describe a fictional case study based on our experiences in the haematological malignancy setting to illustrate the complexities in using genomic testing to evaluate the suitability of relatives to act as stem cell donors. In particular, we demonstrate the ethical issues arising following the identification of a germline variant of uncertain significance (VUS) in a gene associated with inherited cancer susceptibility in a potential recipient. We discuss the factors that need to be considered, such as how this might influence donor selection, the potential for donor-derived leukaemia and the issues of offering testing to other family members.Popular discourse suggests genomics can offer clarity and transformation in healthcare. This case highlights the ethically complex nature of decision-making in genetic medicine due to the familial aspects of genomic information, the uncertain nature of many genomic results and how changes in the use of genomic information in clinical practice can call for urgent decision-making. This highlights the need for increased interdisciplinary working which takes into account the factors driving decisions for each specialty and recommends access to independent ethics support for members of the multidisciplinary team.","PeriodicalId":16317,"journal":{"name":"Journal of Medical Ethics","volume":" ","pages":"672-677"},"PeriodicalIF":4.4,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7619150/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145564235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The case for introducing a minimum NHS service requirement for UK-trained doctors. 为英国培训的医生引入最低NHS服务要求的案例。

IF 4.4 2区哲学

Journal of Medical Ethics Pub Date : 2026-09-22 DOI: 10.1136/jme-2025-111327

Richard Armitage

{"title":"The case for introducing a minimum NHS service requirement for UK-trained doctors.","authors":"Richard Armitage","doi":"10.1136/jme-2025-111327","DOIUrl":"10.1136/jme-2025-111327","url":null,"abstract":"The UK's National Health Service (NHS) faces a persistent workforce crisis, with doctor shortages exacerbated by high attrition and outward migration of UK-trained doctors. Despite extensive public subsidy of medical training-estimated at £250 000 per doctor to the point of full General Medical Council registration-there is currently no requirement for UK-trained doctors to serve a minimum number of years in the NHS. Many UK-trained doctors leave the NHS early in their career, often to practise overseas in healthcare systems that did not contribute to their training. This paper makes the case for introducing a minimum NHS service requirement for UK-trained doctors-advancing a policy proposal grounded in ethical principles-akin to obligations already established in the British Armed Forces for sponsored medical students. The analysis highlights the significant financial burden of training and replacing doctors, estimated at £350 000 per individual lost after 1 year of NHS service, as well as non-financial costs including lost expertise, disrupted continuity of care and opportunity costs arising from oversubscribed medical school places. A minimum service requirement could mitigate these inefficiencies by ensuring a greater return on public investment and encouraging self-selection among applicants more committed to long-term NHS service. Potential objections-including concerns about fairness, autonomy, unintended attrition at later stages and recruitment impacts-are considered and addressed. While further empirical research is needed to refine the optimal duration and assess behavioural impacts, the introduction of a minimum NHS service requirement represents a pragmatic strategy to strengthen workforce retention and protect taxpayer investment.","PeriodicalId":16317,"journal":{"name":"Journal of Medical Ethics","volume":" ","pages":"667-671"},"PeriodicalIF":4.4,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145368095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Why mandatory AI use declarations may be futile and self-defeating. 为什么强制性的人工智能使用声明可能是徒劳和弄巧成拙的。

IF 4.4 2区哲学

Journal of Medical Ethics Pub Date : 2026-09-22 DOI: 10.1136/jme-2026-112404

Hojjat Soofi, Narcyz Ghinea, Ainsley J Newson, Claire Hooker, Tamra Lysaght, Diego S Silva

引用次数: 0

Strengthening harm-theoretic pro-life views. 加强伤害理论的支持生命观点。

IF 4.4 2区哲学

Journal of Medical Ethics Pub Date : 2026-09-22 DOI: 10.1136/jme-2024-110222

Julian I Kanu

引用次数: 0