Case Reports in Gastroenterology最新文献

Spinal Cord Stimulation for Diffuse Visceral Hyperalgesia in the Abdomen: A Case Report and Literature Review. 脊髓刺激治疗腹部弥漫性内脏痛觉过敏1例报告及文献复习。

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-06-18 eCollection Date: 2025-01-01 DOI: 10.1159/000546229

James Mamaril-Davis, Ryan Palsma, Martin Weinand

{"title":"Spinal Cord Stimulation for Diffuse Visceral Hyperalgesia in the Abdomen: A Case Report and Literature Review.","authors":"James Mamaril-Davis, Ryan Palsma, Martin Weinand","doi":"10.1159/000546229","DOIUrl":"10.1159/000546229","url":null,"abstract":"Introduction: Spinal cord stimulation (SCS) for chronic abdominal pain is not novel. However, this has been explored only when the pain has a clear dermatomal association such as the right upper quadrant for sphincter of Oddi dysfunction or the left upper quadrant for post-traumatic splenectomy. The present report thereby discusses the utility of SCS when the visceral pain is diffusely distributed across all four quadrants of the abdomen.Case presentation: A patient in their 70s presented with a 30-year history of chronic abdominal pain diffusely located in all four quadrants. The patient had a pancreatic cyst removed via pancreaticoduodenectomy in 1991 complicated by chronic pancreatitis and visceral hyperalgesia. After failed pharmacological management and various outpatient nerve blocks and trigger point injections, the patient underwent SCS placement via five 4-contact paddle leads at the mid- to superior thoracic 7 level. At 1-month follow-up, the patient's visual analog scale score decreased from 8/10 (prior to implantation) to 0/10. The patient also discontinued his chronic opioid regimen post-SCS placement but continued duloxetine. Device settings remained the same throughout the postoperative period: pulse width of 500 microseconds (inter-burst) and 1,000 microseconds, frequency of 40 Hertz, and current of 1.7 milliamperes. At 12-month follow-up, the patient continued to report >90% pain relief at nearly the same SCS settings as the initial programming.Conclusion: SCS may be a reliable treatment option for chronic abdominal, visceral hyperalgesia when the pain is diffusely located in all 4 quadrants and without a clear dermatomal pattern.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"19 1","pages":"461-466"},"PeriodicalIF":0.5,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12176363/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144324495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Neuromuscular Electrical Stimulation on Chronic Dysphagia in a Single Subject after Anterior Cervical Discectomy and Fusion Surgery: A Case Report. 神经肌肉电刺激对颈椎前路椎间盘切除术和融合手术后慢性吞咽困难的影响：1例报告。

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-06-17 eCollection Date: 2025-01-01 DOI: 10.1159/000546013

Anna Munson, Matthew Dumican, Katherine Rigley

{"title":"Effects of Neuromuscular Electrical Stimulation on Chronic Dysphagia in a Single Subject after Anterior Cervical Discectomy and Fusion Surgery: A Case Report.","authors":"Anna Munson, Matthew Dumican, Katherine Rigley","doi":"10.1159/000546013","DOIUrl":"10.1159/000546013","url":null,"abstract":"Introduction: The purpose of this single subject study was to describe the dysphagia presentation, treatment course, and post-treatment swallowing function in a patient with chronic dysphagia after anterior cervical discectomy and fusion (ACDF) surgery.Case presentation: An 83-year-old male experienced dysphagia >2 months post-ACDF. The patient presented with a narrowed pharyngoesophageal segment due to cervical hardware and reduced epiglottic inversion due to pharyngeal narrowing on videofluoroscopic swallow study (VFSS). He completed dysphagia therapy using neuromuscular electrical stimulation (NMES). Structural alterations and a complicated medical course after treatment impacted therapeutic outcomes. Reductions in penetration or aspiration and improved hyoid excursion were found post-treatment, though impairment persisted. The patient ended therapy after the post-treatment VFSS and began to experience odynophagia and submental pain. The patient experienced a complicated post-treatment course including bilateral cancerous masses at the base of tongue with subsequent surgery and chemoradiation.Conclusions: While considered rare, these findings present a post-operative course of chronic dysphagia post-ACDF surgery where morphological changes to the pharynx significantly altered swallowing function. Swallowing function should be tracked routinely and longitudinally in post-ACDF surgery patients. NMES may be a potential dysphagia therapy modality to explore.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"19 1","pages":"445-454"},"PeriodicalIF":0.5,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12173443/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144315957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Post-Pancreatitis Splenic Artery Pseudoaneurysm as a Luring Danger: A Case Report. 胰腺炎后脾动脉假性动脉瘤的危险：1例报告。

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-06-17 eCollection Date: 2025-01-01 DOI: 10.1159/000546314

Daniel Schweckendiek, Kuno Lehmann, Vincent Van den Bosch

引用次数: 0

Ribavirin Treatment in Acute HEV-Induced Liver Injury in a Healthy US Female: A Case Report. 利巴韦林治疗美国健康女性急性hev诱导肝损伤1例

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-06-17 eCollection Date: 2025-01-01 DOI: 10.1159/000546235

Nadera Altork, Michele P Fischer, Lukman Cheraghvandi, Arul M Thomas

{"title":"Ribavirin Treatment in Acute HEV-Induced Liver Injury in a Healthy US Female: A Case Report.","authors":"Nadera Altork, Michele P Fischer, Lukman Cheraghvandi, Arul M Thomas","doi":"10.1159/000546235","DOIUrl":"10.1159/000546235","url":null,"abstract":"Introduction: Hepatitis E virus (HEV) is a global cause of acute viral hepatitis, for which there is currently no FDA-approved medication. This case report describes a unique instance of a healthy US female presenting with acute HEV, who was treated with ribavirin to address her acute liver injury.Case presentation: A 36-year-old US female, nonpregnant, without liver disease, developed nonspecific symptoms post-travel to Indonesia, leading to acute liver injury with concern for failure. Liver biopsy showed severe hepatocellular necrosis (>50%) with mixed infiltrate; HEV PCR was positive (93,700,000 IU/mL) [Am J Gastroenterol. 2024;119(10S):S2872-3]. After risk-benefit analysis, ribavirin treatment resolved symptoms and normalized biomarkers in a month, avoiding emergency transplantation.Conclusion: HEV infection should be considered in acute liver injury cases in the US, especially with exposure risks. Ribavirin's role in acute cases warrants further study, potentially averting major morbidity and mortality.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"19 1","pages":"455-460"},"PeriodicalIF":0.5,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12173439/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144315959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Opioid Withdrawal Misdiagnosed as a Crohn's Flare. 阿片类药物戒断被误诊为克罗恩病。

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-06-13 eCollection Date: 2025-01-01 DOI: 10.1159/000546335

Matthew Christopher Ryan, Marcel Jose Yibirin Wakim, Sebastian Suarez

引用次数: 0

Curcumin-QingDai Combination as Treatment for Crohn's Disease: A Case Report. 姜黄-清脉联合治疗克罗恩病1例

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-06-11 eCollection Date: 2025-01-01 DOI: 10.1159/000546012

Netanel Krugliak, Mark S Silverberg

引用次数: 0

Diarrhea, Weight Loss, and an Elevated Gastrin: A Case Report. 腹泻、体重减轻和胃泌素升高：1例报告。

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-06-11 eCollection Date: 2025-01-01 DOI: 10.1159/000545714

Ryan G Alexander, John C Cheville, Geoffrey B Thompson, Glenn L Alexander

{"title":"Diarrhea, Weight Loss, and an Elevated Gastrin: A Case Report.","authors":"Ryan G Alexander, John C Cheville, Geoffrey B Thompson, Glenn L Alexander","doi":"10.1159/000545714","DOIUrl":"10.1159/000545714","url":null,"abstract":"Introduction: Hypergastrinemia in a patient with refractory reflux, steatorrhea, or peptic ulcer disease with a gastric pH <4 is concerning for Zollinger-Ellison syndrome (ZES), but antral G-cell hyperplasia can also present in this manner and is distinguished from ZES based on negative radiographic studies and secretory stimulation testing with a typical gastrin response to a standardized test meal.Case presentation: A 51-year-old female with a history of a Nissen fundoplication for refractory reflux presented with a 3-month history of heartburn, diarrhea, and 55-pound weight loss. Evaluation included negative upper and lower endoscopies with biopsies and negative MR enterography. A 48-h fecal fat study revealed 501 g of stool and 51 g of fat per 24 h. A serum gastrin level off PPI was elevated at 589 pg/mL with a gastric pH of 2 on gastric aspirate. An EUS, DOTATATE PET scan, and secretin stimulation test were negative for ZE. A standardized test meal with serial gastrin monitoring demonstrated an 8-fold increase in serum gastrin. Open abdominal exploration and intraoperative ultrasound showed no evidence of a gastrinoma and an antrectomy and Billroth II anastomosis was performed in treatment of G-cell hyperplasia. Pathology demonstrated a moderately increased G-cell population. Postoperatively, her hypergastrinemia and steatorrhea resolved and she regained 60 pounds.Conclusion: Antral G-cell hyperplasia should be considered in patients with symptoms suggestive of gastrinoma with negative secretin stimulation testing and imaging studies. A standardized test meal demonstrates a substantial increase in serum gastrin levels and antrectomy is the treatment of choice for refractory symptoms.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"19 1","pages":"428-433"},"PeriodicalIF":0.5,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12158413/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Calculus Cholecystitis Complicated with Variations of Extrahepatic Bile Duct: Clinical Experience and Aeromedical Analysis of 3 Cases in Aviation Pilots. 航空飞行员结石性胆囊炎合并肝外胆管病变3例临床体会及航空医学分析。

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-06-09 eCollection Date: 2025-01-01 DOI: 10.1159/000546233

Wen-Bing Li, Zeng Xue, Wei Shi, Lu-Bing Wang, Xiao-Jun He, Cheng Wang, Gang Zhao, Ling-Hong Kong, Meng Pu, Cheng-Li Liu, Ya-Lin Kong

{"title":"Calculus Cholecystitis Complicated with Variations of Extrahepatic Bile Duct: Clinical Experience and Aeromedical Analysis of 3 Cases in Aviation Pilots.","authors":"Wen-Bing Li, Zeng Xue, Wei Shi, Lu-Bing Wang, Xiao-Jun He, Cheng Wang, Gang Zhao, Ling-Hong Kong, Meng Pu, Cheng-Li Liu, Ya-Lin Kong","doi":"10.1159/000546233","DOIUrl":"10.1159/000546233","url":null,"abstract":"Introduction: For aviation personnel, calculous cholecystitis often requires surgical treatment because of the potential risks to flight safety whether symptomatic or asymptomatic. Although much effort has been put on the precaution of gallstone formation, the incidence of long-term post-cholecystectomy syndrome (PCS) seems more apparent in the limited number of cases undergoing cholecystectomy. The purpose of article was to elucidate the possible mechanism of gallstone formation and the development of long-term PCS caused by variations of bile duct, as well as choice of surgical treatments, just in this particular group of aviation personnel.Case presentation: Seven aviation pilots who underwent laparoscopic cholecystectomy in recent 5 years were reviewed, and 3 cases who developed long-term PCS because of variations of bile duct were presented. Variations of bile duct included existence of accessory extrahepatic bile, absence of common bile duct, and absence of cystic duct. Long-term PCS was characterized as epigastric dull pain and diarrhea or sparse stool, and became aggravated when resuming trainings of flight stimulations. Dietary adjustment and oral antispasmodic or cholagogic drug therapy, combined with relieving apprehensions after surgery, helped them recover well and resume flight.Conclusion: Variation of bile duct may be an important potential risk for gallstone formation and development of long-term PCS with the cause of probable decrement of bile drainage under the physiological environment of aviation.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"19 1","pages":"412-422"},"PeriodicalIF":0.5,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12148319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

First Description of Sprue-Like Enteropathy due to Azilsartan: A Case Report. 阿兹沙坦引起的云杉样肠病1例报告。

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-06-06 eCollection Date: 2025-01-01 DOI: 10.1159/000545217

Luisa Stoeckli, Markus Koster, Tugce Tuerkmen-Uthayanan, Sergio Cogliatti, Stephan Brand

{"title":"First Description of Sprue-Like Enteropathy due to Azilsartan: A Case Report.","authors":"Luisa Stoeckli, Markus Koster, Tugce Tuerkmen-Uthayanan, Sergio Cogliatti, Stephan Brand","doi":"10.1159/000545217","DOIUrl":"10.1159/000545217","url":null,"abstract":"Introduction: Sartan-induced enteropathy is an uncommon side effect of treatment with angiotensin II receptor antagonists (ARBs), which has predominantly been described for olmesartan.Case presentation: For the first time, we describe sartan-induced enteropathy as an adverse drug reaction associated with azilsartan in a 74-year-old male patient who was admitted to the hospital twice within 5 months because of excessive non-bloody diarrhea and weight loss. In this case, histopathological findings of intraepithelial lymphocytosis and intestinal villous atrophy resembled celiac disease; however, celiac disease-specific antibodies remained negative, and a gluten-free diet did not result in significant clinical recovery, while symptoms stopped rapidly after stopping azilsartan. When the patient was seen 5 months later, he was free of clinical symptoms, and histological changes disappeared after stopping azilsartan.Conclusion: This case illustrates sprue-like enteropathy as a potential side effect of azilsartan, emphasizing to consider this differential diagnosis in ARB-treated patients with chronic diarrhea. The causality of our findings was confirmed by drug de-challenge and re-challenge resulting in typical histological changes.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"19 1","pages":"403-411"},"PeriodicalIF":0.5,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12143864/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case of Recurrent Gallstone Ileus Treated with Enterolithotomy Alone. 单纯肠内取石术治疗复发性胆结石性肠梗阻1例。

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-06-05 eCollection Date: 2025-01-01 DOI: 10.1159/000545980

Kisho Noda, Hirofumi Ohno, Keiko Naito, Katsudai Shirakabe, Hirotada Muramatsu, Hiraku Funakoshi

引用次数: 0