Case Reports in Gastroenterology最新文献_第2页

Inflammatory Bowel Disease in a Patient Returning from Colombia: Association with Dipeptidyl Peptidase 4 Inhibitor?

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-02-21 eCollection Date: 2025-01-01 DOI: 10.1159/000543680

Ahmed B Bayoumy, Gwen M C Masclee, Nanne K H de Boer, Andra Neefjes-Borst, Dirk Jan Stenvers

{"title":"Inflammatory Bowel Disease in a Patient Returning from Colombia: Association with Dipeptidyl Peptidase 4 Inhibitor?","authors":"Ahmed B Bayoumy, Gwen M C Masclee, Nanne K H de Boer, Andra Neefjes-Borst, Dirk Jan Stenvers","doi":"10.1159/000543680","DOIUrl":"10.1159/000543680","url":null,"abstract":"Introduction: Recent-onset colitis poses a diagnostic challenge, necessitating a thorough evaluation to identify potential infectious and non-infectious etiologies. We considered inflammatory bowel disease (IBD) secondary to dipeptidyl peptidase 4 (DPP-4) inhibitor-induced colitis.Case presentation: This case report details the presentation and management of a patient with persistent dysentery, refractory to conventional treatments, ultimately attributed to IBD possibly secondary to long-term DPP-4 inhibitor use. Following an episode of suspected amebiasis, the patient experienced prolonged bloody diarrhea with an endoscopic image compatible with ulcerative colitis. Extensive infectious diagnostics were negative. Ultimately, the cessation of sitagliptin therapy resulted in rapid symptom resolution and normalization of eosinophilia, as well as endoscopic improvement. However, after a few weeks, the patient was readmitted with diarrhea after continued cessation of sitagliptin.Conclusion: This case underscores the importance of considering IBD secondary to DPP-4 inhibitor use in the evaluation of patients with recent-onset IBD. Further research is needed to elucidate the pathophysiological mechanisms underlying the relationship between DPP-4 inhibitors and IBD.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"19 1","pages":"89-95"},"PeriodicalIF":0.5,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11845166/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Severe Acute Pancreatitis Complicated by Multiple Intra-Abdominal Hemorrhages.

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-02-19 eCollection Date: 2025-01-01 DOI: 10.1159/000543626

Cong-Yu Wang, Yin Gu, Rui-Peng Yan, Xin Li, Fei He, Xiang-Lan Feng, Gen Zhang, Yun-Feng Cui

{"title":"Severe Acute Pancreatitis Complicated by Multiple Intra-Abdominal Hemorrhages.","authors":"Cong-Yu Wang, Yin Gu, Rui-Peng Yan, Xin Li, Fei He, Xiang-Lan Feng, Gen Zhang, Yun-Feng Cui","doi":"10.1159/000543626","DOIUrl":"10.1159/000543626","url":null,"abstract":"Introduction: Intra-abdominal hemorrhage is a rare yet life-threatening complication of acute pancreatitis (AP), with a higher prevalence in cases of severe acute pancreatitis (SAP). This condition is primarily caused by vessel wall erosion and rupture of pseudoaneurysms (PSAs). However, SAP cases involving multiple sequential arterial hemorrhages are extremely rare. This condition is primarily brought on by the process of vessel wall degeneration and the development of PSAs. Nonetheless, SAP necessitating multiple episodes of arterial bleeding is very uncommon.Case presentation: Here is the case history of a 31-year-old man already being treated for SAP. His condition was then complicated by massive, frequent intra-abdominal bleeding. The patient initially presented to the hospital with SAP. He was transferred to the intensive care unit for proper management. Massive intra-abdominal bleeds occurred on the 31st, 45th, and 60th days during hospitalization. The maximum blood loss was 1,500 mL. In each of the instances, digital subtraction angiography (DSA) embolization was carried out after the bleeding source had been verified. In order to manage SAP, continuous percutaneous drainage and staged pancreatic necrosectomy were undertaken for 6 months. No recurrence of intra-abdominal hemorrhage was detected. Infection of the abdominal cavity was properly controlled. The patient left the hospital in good condition.Conclusion: Spontaneous bleeding in the abdominal cavity is a severe and life-threatening complication of SAP. This is often caused by vessel wall erosion. In such cases, DSA plays a crucial role in diagnosis and management. Besides precisely locating the bleeding source, one can perform a much-needed embolization immediately. Consequently, the disease is under total control, and the patient is much more likely to survive.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"19 1","pages":"79-88"},"PeriodicalIF":0.5,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11839214/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143457018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hybrid Endoscopic/Fluoroscopic Gastrostomy Tube Placement: Case Report of a Novel Technique.

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-02-18 eCollection Date: 2025-01-01 DOI: 10.1159/000542809

Nicholas Girardi, Benjamin Wharton, Kenneth Cicuto, Alysia Wiley, Lacey LaGrone

引用次数: 0

Management of Refractory Esophageal Variceal Bleeding when TIPSS Is Not Possible: Review of a Challenging Case.

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-02-13 eCollection Date: 2025-01-01 DOI: 10.1159/000543537

Abdulrahman Qatomah, Ali Bessissow, Yen-I Chen, Talat Bessissow, Amine Benmassaoud

引用次数: 0

Anaphylaxis to a Vedolizumab Infusion following Drug Holiday in a Patient with Ulcerative Colitis: A Case Report.

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-02-12 eCollection Date: 2025-01-01 DOI: 10.1159/000543387

Jadon Karp, Henry Shen, Thomas Goodwin, Miles P Sparrow

{"title":"Anaphylaxis to a Vedolizumab Infusion following Drug Holiday in a Patient with Ulcerative Colitis: A Case Report.","authors":"Jadon Karp, Henry Shen, Thomas Goodwin, Miles P Sparrow","doi":"10.1159/000543387","DOIUrl":"10.1159/000543387","url":null,"abstract":"Introduction: Vedolizumab is a commonly prescribed biologic agent due to its safety profile and clinical efficacy. Severe infusion-related reactions are exceedingly rare, with no previously documented cases of anaphylaxis to vedolizumab infusion following a drug holiday.Case presentation: We report the case of a 65-year-old male with ulcerative colitis who had a severe anaphylactic reaction to the first re-induction infusion of vedolizumab following a 30-month drug holiday. No pre-infusion prophylactic medication was administered. Upon commencement of the infusion, the patient developed anaphylactic symptoms including airway compromise that required intensive care unit admission and treatment with an adrenaline infusion.Conclusion: Anaphylactic reactions to vedolizumab after a drug holiday can occur. As is done for infliximab, we recommend administration of an antipyretic, antihistamine, and corticosteroid prior to vedolizumab re-induction infusions when it is given after a drug holiday.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"19 1","pages":"62-66"},"PeriodicalIF":0.5,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11820661/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful Pregnancy in a Patient with Crohn's Disease and Short Bowel Syndrome: Off Total Parenteral Nutrition and On Teduglutide, a Glucagon-Like Peptide-2 Analog - A Case Report. 克罗恩病和短肠综合征患者成功怀孕：脱离全肠外营养并服用胰高血糖素样肽-2类似物泰度鲁肽--病例报告。

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-02-04 eCollection Date: 2025-01-01 DOI: 10.1159/000543291

Maria M Dahar, MacKenzie Both, Linda M Lord, Carly Densmore, Lawrence J Saubermann

{"title":"Successful Pregnancy in a Patient with Crohn's Disease and Short Bowel Syndrome: Off Total Parenteral Nutrition and On Teduglutide, a Glucagon-Like Peptide-2 Analog - A Case Report.","authors":"Maria M Dahar, MacKenzie Both, Linda M Lord, Carly Densmore, Lawrence J Saubermann","doi":"10.1159/000543291","DOIUrl":"10.1159/000543291","url":null,"abstract":"Introduction: Patients with short bowel syndrome (SBS) on conventional oral diets often face nutritional deficiencies and dehydration, a challenge further compounded during pregnancy. This case report describes the use of a glucagon-like peptide-2 (GLP-2) analog in the nutritional management of an SBS patient dependent on total parenteral nutrition (TPN).Case presentation: A 29-year-old woman with a significant medical history of Crohn's disease leading to SBS was traditionally dependent on TPN for sustenance. During her pregnancy, she was successfully managed with a GLP-2 analog, which enabled her to wean off TPN. This successful management underscores the therapeutic potential of GLP-2 analogs in effectively altering the nutritional landscape for SBS patients, including during the physiologically demanding period of pregnancy.Conclusion: GLP-2 analogs helped with the nutritional management of patients with SBS during pregnancy and helped them wean off TPN. There is a need for further research and exploration into GLP-2 analogs as viable alternatives to conventional treatments such as TPN in the care and management of SBS patients during pregnancy.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"19 1","pages":"57-61"},"PeriodicalIF":0.5,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11793910/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143188412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Colonic Dieulafoy Lesion as a Rare Cause of Lower Gastrointestinal Bleeding.

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-01-31 eCollection Date: 2025-01-01 DOI: 10.1159/000542790

Mohamed Farag, Yordanka Diaz, Harish Patel

{"title":"Colonic Dieulafoy Lesion as a Rare Cause of Lower Gastrointestinal Bleeding.","authors":"Mohamed Farag, Yordanka Diaz, Harish Patel","doi":"10.1159/000542790","DOIUrl":"10.1159/000542790","url":null,"abstract":"Introduction: Dieulafoy lesion is one of the most under-recognized sources of gastrointestinal (GI) bleeding (GI), typically manifesting as acute upper gastrointestinal bleeding; endoscopy is usually the first diagnostic and therapeutic modality utilized to handle these lesions by employing a variety of procedures.Case report: This is a case of an 81-year-old female who was being assessed after experiencing repeated bouts of melena with hemoglobin drop. The patient had multiple comorbidities but no history of gastrointestinal bleeding. Esophagogastroduodenoscopy (EGD) revealed only Erythematous duodenopathy without active bleeding; the initial colonoscopy revealed a large amount of blood without identifying the source of bleeding; a second colonoscopy revealed classic Dieulafoy lesions in the splenic flexure, which were injected and clipped, and the bleeding ceased.Conclusion: Dieulafoy lesions are most frequently found in the stomach and gastroesophageal junction, but they have also been documented in other parts of the gastrointestinal tract. In this particular instance, the lesions were identified in the colon, which is an unusual location for them, and they were treated endoscopically by clipping and injecting. In conclusion, colonic Dieulafoy lesions, although rare, have the potential to cause life-threatening bleeding and should be included in the differential diagnosis of lower gastrointestinal bleeding.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"19 1","pages":"52-56"},"PeriodicalIF":0.5,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11785396/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143077916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rare Encounter: A Case Report of Hepatic Perivascular Epithelioid Cell Tumor - An Uncommon Mesenchymal Tumor in the Liver.

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-01-24 eCollection Date: 2025-01-01 DOI: 10.1159/000543018

Diogo Paula, Maria João Amaral, Joana Madeira, João Simões, André Lázaro, Nuno Silva, José Guilherme Tralhão

{"title":"Rare Encounter: A Case Report of Hepatic Perivascular Epithelioid Cell Tumor - An Uncommon Mesenchymal Tumor in the Liver.","authors":"Diogo Paula, Maria João Amaral, Joana Madeira, João Simões, André Lázaro, Nuno Silva, José Guilherme Tralhão","doi":"10.1159/000543018","DOIUrl":"10.1159/000543018","url":null,"abstract":"Introduction: Perivascular epithelioid cell tumor (PEComa) is a rare neoplastic mesenchymal tumor, more frequently found in the uterus, although it can occur in different organs. Hepatic PEComa is extremely rare, with only a few cases described in the literature.Case presentation: We present a case report of a 33-year-old female patient with a history of macroprolactinoma. She was initially referred to our Department due to a 9-mm hepatic nodule incidentally diagnosed in an abdominal ultrasound in 2018. She was asymptomatic. Follow-up ultrasound showed a growth from 9 mm to 16 mm in 2019 and 30 mm in a liver magnetic resonance imaging (MRI) scan in 2022. The case was discussed in a multidisciplinary team meeting, and since malignant transformation or hepatocellular carcinoma could not be ruled out, the decision was to undergo hepatic resection. An open hepatic subsegmentectomy of segment 5 was performed, with uneventful postoperative period. The definitive diagnosis was hepatic PEComa.Conclusion: Hepatic PEComas are rare liver tumors, and their preoperative diagnosis is challenging due to the lack of specific radiological features. In most cases, the diagnosis is only confirmed through histopathological and immunohistochemical studies. Resection of the lesion appears to be the curative treatment; however, due to the rarity of the condition, there are no studies comparing surgical treatment with other options. In our case, the hypervascular lesion was initially misdiagnosed as an adenoma. PEComas should be considered as a differential diagnosis in liver nodules with well-defined margins and increased uptake in the arterial phase in computed tomography or MRI scan. Surgical resection was curative, and no recurrence was detected during the patient's follow-up.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"19 1","pages":"43-51"},"PeriodicalIF":0.5,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11759453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Colitis-Induced Pancreatic Fistula with Pancreatic Ascites.

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-01-16 eCollection Date: 2025-01-01 DOI: 10.1159/000543007

Evan Winrich, Ethan Steele, Amal Shine, Dipendra Parajuli

引用次数: 0

Jackhammer Esophagus as a Complication of Tonsillectomy and Adenoidectomy: A Case Report.

IF 0.5

Case Reports in Gastroenterology Pub Date : 2025-01-14 eCollection Date: 2025-01-01 DOI: 10.1159/000542891

W Michael McDonnell, Alison Tewnion

引用次数: 0